George R. Uhl - Publications

Affiliations: 
National Institute on Drug Abuse 
Area:
Human genetics, Drug abuse

265 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Musci RJ, Uhl G, Maher B, Ialongo NS. Testing gene × environment moderation of tobacco and marijuana use trajectories in adolescence and young adulthood. Journal of Consulting and Clinical Psychology. 83: 866-74. PMID 26214541 DOI: 10.1037/a0039537  1
2015 Drgonova J, Walther D, Singhal S, Johnson K, Kessler B, Troncoso J, Uhl GR. Altered CSMD1 Expression Alters Cocaine-Conditioned Place Preference: Mutual Support for a Complex Locus from Human and Mouse Models. Plos One. 10: e0120908. PMID 26171607 DOI: 10.1371/journal.pone.0120908  1
2015 Zhong X, Drgonova J, Li CY, Uhl GR. Human cell adhesion molecules: annotated functional subtypes and overrepresentation of addiction-associated genes. Annals of the New York Academy of Sciences. 1349: 83-95. PMID 25988664 DOI: 10.1111/nyas.12776  1
2015 Kitanaka J, Kitanaka N, Hall FS, Fujii M, Goto A, Kanda Y, Koizumi A, Kuroiwa H, Mibayashi S, Muranishi Y, Otaki S, Sumikawa M, Tanaka K, Nishiyama N, Uhl GR, et al. Memory impairment and reduced exploratory behavior in mice after administration of systemic morphine. Journal of Experimental Neuroscience. 9: 27-35. PMID 25987850 DOI: 10.4137/JEN.S25057  1
2015 Musci RJ, Masyn KE, Benke K, Maher B, Uhl G, Ialongo NS. The effects of the interplay of genetics and early environmental risk on the course of internalizing symptoms from late childhood through adolescence. Development and Psychopathology. 1-13. PMID 25936925 DOI: 10.1017/S0954579415000401  1
2015 Kasahara Y, Arime Y, Hall FS, Uhl GR, Sora I. Region-specific dendritic spine loss of pyramidal neurons in dopamine transporter knockout mice. Current Molecular Medicine. 15: 237-44. PMID 25817859  1
2015 Takamatsu Y, Hagino Y, Sato A, Takahashi T, Nagasawa SY, Kubo Y, Mizuguchi M, Uhl GR, Sora I, Ikeda K. Improvement of learning and increase in dopamine level in the frontal cortex by methylphenidate in mice lacking dopamine transporter. Current Molecular Medicine. 15: 245-52. PMID 25817856  1
2015 Piao YS, Hall FS, Moriya Y, Ito M, Ohara A, Kikura-Hanajiri R, Goda Y, Lesch KP, Murphy DL, Uhl GR, Sora I. Methylone-induced hyperthermia and lethal toxicity: role of the dopamine and serotonin transporters. Behavioural Pharmacology. 26: 345-52. PMID 25794333 DOI: 10.1097/FBP.0000000000000135  1
2015 Lee CT, Bendriem RM, Kindberg AA, Worden LT, Williams MP, Drgon T, Mallon BS, Harvey BK, Richie CT, Hamilton RS, Chen J, Errico SL, Tsai SY, Uhl GR, Freed WJ. Functional consequences of 17q21.31/WNT3-WNT9B amplification in hPSCs with respect to neural differentiation. Cell Reports. 10: 616-32. PMID 25640183 DOI: 10.1016/j.celrep.2014.12.050  1
2015 Igari M, Shen HW, Hagino Y, Fukushima S, Kasahara Y, Lesch KP, Murphy DL, Hall FS, Uhl GR, Ikeda K, Yaegashi N, Sora I. Attenuated methamphetamine-induced locomotor sensitization in serotonin transporter knockout mice is restored by serotonin 1B receptor antagonist treatment. Behavioural Pharmacology. 26: 167-79. PMID 25485646 DOI: 10.1097/FBP.0000000000000120  1
2015 Moriya Y, Kasahara Y, Hall FS, Sakakibara Y, Uhl GR, Tomita H, Sora I. Sex differences in the effects of adolescent social deprivation on alcohol consumption in μ-opioid receptor knockout mice. Psychopharmacology. 232: 1471-82. PMID 25363463 DOI: 10.1007/s00213-014-3784-y  1
2015 Sasaki K, Sumiyoshi A, Nonaka H, Kasahara Y, Ikeda K, Hall FS, Uhl GR, Watanabe M, Kawashima R, Sora I. Specific regions display altered grey matter volume in μ-opioid receptor knockout mice: MRI voxel-based morphometry. British Journal of Pharmacology. 172: 654-67. PMID 24913308 DOI: 10.1111/bph.12807  1
2014 Uhl GR. Preface for Addiction Reviews. Annals of the New York Academy of Sciences. 1327: v. PMID 25336391 DOI: 10.1111/nyas.12563  1
2014 Sakakibara Y, Kasahara Y, Hall FS, Lesch KP, Murphy DL, Uhl GR, Sora I. Developmental alterations in anxiety and cognitive behavior in serotonin transporter mutant mice. Psychopharmacology. 231: 4119-33. PMID 24728652 DOI: 10.1007/s00213-014-3554-x  1
2014 Kitanaka N, Kitanaka J, Hall FS, Uhl GR, Watabe K, Kubo H, Takahashi H, Tanaka K, Nishiyama N, Takemura M. Agmatine attenuates methamphetamine-induced hyperlocomotion and stereotyped behavior in mice. Behavioural Pharmacology. 25: 158-65. PMID 24557322 DOI: 10.1097/FBP.0000000000000030  1
2014 Uhl GR, Drgonova J. Cell adhesion molecules: druggable targets for modulating the connectome and brain disorders? Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 39: 235. PMID 24317312 DOI: 10.1038/npp.2013.240  1
2014 Uhl GR, Drgonova J, Hall FS. Curious cases: Altered dose-response relationships in addiction genetics. Pharmacology & Therapeutics. 141: 335-46. PMID 24189489 DOI: 10.1016/j.pharmthera.2013.10.013  1
2014 Musci RJ, Bradshaw CP, Maher B, Uhl GR, Kellam SG, Ialongo NS. Reducing aggression and impulsivity through school-based prevention programs: a gene by intervention interaction. Prevention Science : the Official Journal of the Society For Prevention Research. 15: 831-40. PMID 24178584 DOI: 10.1007/s11121-013-0441-3  1
2014 Hall FS, Itokawa K, Schmitt A, Moessner R, Sora I, Lesch KP, Uhl GR. Decreased vesicular monoamine transporter 2 (VMAT2) and dopamine transporter (DAT) function in knockout mice affects aging of dopaminergic systems. Neuropharmacology. 76: 146-55. PMID 23978383 DOI: 10.1016/j.neuropharm.2013.07.031  1
2014 Uhl GR, Walther D, Musci R, Fisher C, Anthony JC, Storr CL, Behm FM, Eaton WW, Ialongo N, Rose JE. Smoking quit success genotype score predicts quit success and distinct patterns of developmental involvement with common addictive substances. Molecular Psychiatry. 19: 50-4. PMID 23128154 DOI: 10.1038/mp.2012.155  1
2014 Ishiguro H, Hall FS, Horiuchi Y, Sakurai T, Hishimoto A, Grumet M, Uhl GR, Onaivi ES, Arinami T. NrCAM-regulating neural systems and addiction-related behaviors. Addiction Biology. 19: 343-53. PMID 22780223 DOI: 10.1111/j.1369-1600.2012.00469.x  1
2013 Drgonova J, Jacobsson JA, Han JC, Yanovski JA, Fredriksson R, Marcus C, Schiöth HB, Uhl GR. Involvement of the neutral amino acid transporter SLC6A15 and leucine in obesity-related phenotypes. Plos One. 8: e68245. PMID 24023709 DOI: 10.1371/journal.pone.0068245  1
2013 Hall FS, Drgonova J, Jain S, Uhl GR. Implications of genome wide association studies for addiction: are our a priori assumptions all wrong? Pharmacology & Therapeutics. 140: 267-79. PMID 23872493 DOI: 10.1016/j.pharmthera.2013.07.006  1
2013 Kitanaka J, Kitanaka N, Hall FS, Uhl GR, Fukushima Y, Sawai T, Watabe K, Kubo H, Takahashi H, Tanaka K, Nishiyama N, Tatsuta T, Morita Y, Takemura M. The selective μ opioid receptor antagonist β-funaltrexamine attenuates methamphetamine-induced stereotypical biting in mice. Brain Research. 1522: 88-98. PMID 23727404 DOI: 10.1016/j.brainres.2013.05.027  1
2013 Bough KJ, Lerman C, Rose JE, McClernon FJ, Kenny PJ, Tyndale RF, David SP, Stein EA, Uhl GR, Conti DV, Green C, Amur S. Biomarkers for smoking cessation. Clinical Pharmacology and Therapeutics. 93: 526-38. PMID 23588313 DOI: 10.1038/clpt.2013.57  1
2013 Hägglund MG, Roshanbin S, Löfqvist E, Hellsten SV, Nilsson VC, Todkar A, Zhu Y, Stephansson O, Drgonova J, Uhl GR, Schiöth HB, Fredriksson R. B(0)AT2 (SLC6A15) is localized to neurons and astrocytes, and is involved in mediating the effect of leucine in the brain. Plos One. 8: e58651. PMID 23505546 DOI: 10.1371/journal.pone.0058651  1
2013 Gallagher JJ, Zhang X, Hall FS, Uhl GR, Bearer EL, Jacobs RE. Altered reward circuitry in the norepinephrine transporter knockout mouse. Plos One. 8: e57597. PMID 23469209 DOI: 10.1371/journal.pone.0057597  1
2013 Fox MA, Panessiti MG, Hall FS, Uhl GR, Murphy DL. An evaluation of the serotonin system and perseverative, compulsive, stereotypical, and hyperactive behaviors in dopamine transporter (DAT) knockout mice. Psychopharmacology. 227: 685-95. PMID 23417514 DOI: 10.1007/s00213-013-2988-x  1
2013 Ohara A, Kasahara Y, Yamamoto H, Hata H, Kobayashi H, Numachi Y, Miyoshi I, Hall FS, Uhl GR, Ikeda K, Sora I. Exclusive expression of VMAT2 in noradrenergic neurons increases viability of homozygous VMAT2 knockout mice. Biochemical and Biophysical Research Communications. 432: 526-32. PMID 23410751 DOI: 10.1016/j.bbrc.2013.02.014  1
2013 Yamashita M, Sakakibara Y, Hall FS, Numachi Y, Yoshida S, Kobayashi H, Uchiumi O, Uhl GR, Kasahara Y, Sora I. Impaired cliff avoidance reaction in dopamine transporter knockout mice. Psychopharmacology. 227: 741-9. PMID 23397052 DOI: 10.1007/s00213-013-3009-9  1
2013 Bruehl S, Apkarian AV, Ballantyne JC, Berger A, Borsook D, Chen WG, Farrar JT, Haythornthwaite JA, Horn SD, Iadarola MJ, Inturrisi CE, Lao L, Mackey S, Mao J, Sawczuk A, ... Uhl GR, et al. Personalized medicine and opioid analgesic prescribing for chronic pain: opportunities and challenges. The Journal of Pain : Official Journal of the American Pain Society. 14: 103-13. PMID 23374939 DOI: 10.1016/j.jpain.2012.10.016  1
2013 Uchiumi O, Kasahara Y, Fukui A, Hall FS, Uhl GR, Sora I. Serotonergic involvement in the amelioration of behavioral abnormalities in dopamine transporter knockout mice by nicotine. Neuropharmacology. 64: 348-56. PMID 22809709 DOI: 10.1016/j.neuropharm.2012.07.016  1
2013 Berrocoso E, Ikeda K, Sora I, Uhl GR, Sánchez-Blázquez P, Mico JA. Active behaviours produced by antidepressants and opioids in the mouse tail suspension test. The International Journal of Neuropsychopharmacology / Official Scientific Journal of the Collegium Internationale Neuropsychopharmacologicum (Cinp). 16: 151-62. PMID 22217458 DOI: 10.1017/S1461145711001842  1
2013 Uhl GR. Preface to Addiction Reviews Annals of the New York Academy of Sciences. 1282: iv. DOI: 10.1111/nyas.12100  1
2013 Uhl GR, Walther D, Drgon T. Genetics of Substance Use, Abuse, Cessation, and Addiction. Novel Data Implicate Copy Number Variants The Effects of Drug Abuse On the Human Nervous System. 37-50. DOI: 10.1016/B978-0-12-418679-8.00002-2  1
2012 Kitanaka J, Kitanaka N, Hall FS, Uhl GR, Tanaka K, Nishiyama N, Takemura M. Straub tail reaction in mice treated with σ(1) receptor antagonist in combination with methamphetamine. Brain Research. 1482: 40-6. PMID 22981417 DOI: 10.1016/j.brainres.2012.09.001  1
2012 Arime Y, Kasahara Y, Hall FS, Uhl GR, Sora I. Cortico-subcortical neuromodulation involved in the amelioration of prepulse inhibition deficits in dopamine transporter knockout mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 37: 2522-30. PMID 22781838 DOI: 10.1038/npp.2012.114  1
2012 Munafò MR, Timofeeva MN, Morris RW, Prieto-Merino D, Sattar N, Brennan P, Johnstone EC, Relton C, Johnson PC, Walther D, Whincup PH, Casas JP, Uhl GR, Vineis P, Padmanabhan S, et al. Association between genetic variants on chromosome 15q25 locus and objective measures of tobacco exposure. Journal of the National Cancer Institute. 104: 740-8. PMID 22534784 DOI: 10.1093/jnci/djs191  1
2012 Ramadan E, Chang L, Chen M, Ma K, Hall FS, Uhl GR, Rapoport SI, Basselin M. Knocking out the dopamine reuptake transporter (DAT) does not change the baseline brain arachidonic acid signal in the mouse. The International Journal of Neuroscience. 122: 373-80. PMID 22376027 DOI: 10.3109/00207454.2012.665972  1
2012 Hall FS, Markou A, Levin ED, Uhl GR. Mouse models for studying genetic influences on factors determining smoking cessation success in humans. Annals of the New York Academy of Sciences. 1248: 39-70. PMID 22304675 DOI: 10.1111/j.1749-6632.2011.06415.x  1
2012 Kitanaka J, Kitanaka N, Hall FS, Uhl GR, Asano H, Chatani R, Hayata S, Yokoyama H, Tanaka K, Nishiyama N, Takemura M. Pretreatment with nomifensine or nomifensine analogue 4-phenyl-1,2,3,4-tetrahydroisoquinoline augments methamphetamine-induced stereotypical behavior in mice. Brain Research. 1439: 15-26. PMID 22265332 DOI: 10.1016/j.brainres.2011.12.043  1
2012 Kitanaka N, Kitanaka J, Hall FS, Uhl GR, Watabe K, Kubo H, Takahashi H, Tatsuta T, Morita Y, Takemura M. A single administration of methamphetamine to mice early in the light period decreases running wheel activity observed during the dark period. Brain Research. 1429: 155-63. PMID 22079320 DOI: 10.1016/j.brainres.2011.10.037  1
2012 Hall FS, Centeno M, Perona MT, Adair J, Dobner PR, Uhl GR. Effects of neurotensin gene knockout in mice on the behavioral effects of cocaine. Psychopharmacology. 219: 35-45. PMID 21720755 DOI: 10.1007/s00213-011-2370-9  1
2012 Leventhal AM, David SP, Brightman M, Strong D, McGeary JE, Brown RA, Lloyd-Richardson EE, Munafò M, Uhl GR, Niaura R. Dopamine D4 receptor gene variation moderates the efficacy of bupropion for smoking cessation. The Pharmacogenomics Journal. 12: 86-92. PMID 20661272 DOI: 10.1038/tpj.2010.64  1
2012 Kitanaka N, Kitanaka J, Hall SS, Uhl GR, Watabe K, Kubo H, Takahashi H, Takemura M. Attenuation of methamphetamine-induced conditioned place preference in mice after a drug-free period and facilitation of this effect by exposure to a running wheel Journal of Experimental Neuroscience. 6: 11-19. DOI: 10.4137/JEN.S10046  1
2012 Uhl GR, Drgon T. Genetic contributions to individual differences in vulnerability to addiction and abilities to quit Drug Abuse and Addiction in Medical Illness: Causes, Consequences and Treatment. 2147483647: 95-105. DOI: 10.1007/978-1-4614-3375-0_7  1
2011 Li CY, Zhou WZ, Zhang PW, Johnson C, Wei L, Uhl GR. Meta-analysis and genome-wide interpretation of genetic susceptibility to drug addiction. Bmc Genomics. 12: 508. PMID 21999673 DOI: 10.1186/1471-2164-12-508  1
2011 Kasai S, Yamamoto H, Kamegaya E, Uhl GR, Sora I, Watanabe M, Ikeda K. Quantitative Detection of µ Opioid Receptor: Western Blot Analyses Using µ Opioid Receptor Knockout Mice. Current Neuropharmacology. 9: 219-22. PMID 21886594 DOI: 10.2174/157015911795016921  1
2011 Hagino Y, Takamatsu Y, Yamamoto H, Iwamura T, Murphy DL, Uhl GR, Sora I, Ikeda K. Effects of MDMA on Extracellular Dopamine and Serotonin Levels in Mice Lacking Dopamine and/or Serotonin Transporters. Current Neuropharmacology. 9: 91-5. PMID 21886569 DOI: 10.2174/157015911795017254  1
2011 Johnson C, Drgon T, Walther D, Uhl GR. Genomic regions identified by overlapping clusters of nominally-positive SNPs from genome-wide studies of alcohol and illegal substance dependence. Plos One. 6: e19210. PMID 21818250 DOI: 10.1371/journal.pone.0019210  1
2011 Uhl GR, Walther D, Behm FM, Rose JE. Menthol preference among smokers: association with TRPA1 variants. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 13: 1311-5. PMID 21719896 DOI: 10.1093/ntr/ntr119  1
2011 Komatsu H, Ohara A, Sasaki K, Abe H, Hattori H, Hall FS, Uhl GR, Sora I. Decreased response to social defeat stress in μ-opioid-receptor knockout mice. Pharmacology, Biochemistry, and Behavior. 99: 676-82. PMID 21703297 DOI: 10.1016/j.pbb.2011.06.008  1
2011 Munafò MR, Johnstone EC, Walther D, Uhl GR, Murphy MF, Aveyard P. CHRNA3 rs1051730 genotype and short-term smoking cessation. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 13: 982-8. PMID 21690317 DOI: 10.1093/ntr/ntr106  1
2011 Kitanaka J, Kitanaka N, Hall FS, Uhl GR, Tatsuta T, Morita Y, Tanaka K, Nishiyama N, Takemura M. Histamine H3 receptor agonists decrease hypothalamic histamine levels and increase stereotypical biting in mice challenged with methamphetamine. Neurochemical Research. 36: 1824-33. PMID 21573995 DOI: 10.1007/s11064-011-0500-8  1
2011 Ide S, Minami M, Uhl GR, Satoh M, Sora I, Ikeda K. (-)-Pentazocine induces visceral chemical antinociception, but not thermal, mechanical, or somatic chemical antinociception, in μ-opioid receptor knockout mice. Molecular Pain. 7: 23. PMID 21477373 DOI: 10.1186/1744-8069-7-23  1
2011 Drgon T, Johnson CA, Nino M, Drgonova J, Walther DM, Uhl GR. "Replicated" genome wide association for dependence on illegal substances: genomic regions identified by overlapping clusters of nominally positive SNPs. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 156: 125-38. PMID 21302341 DOI: 10.1002/ajmg.b.31143  1
2011 Ramachandra V, Kang F, Kim C, Nova AS, Bajaj A, Hall FS, Uhl GR, Gonzales RA. The μ opioid receptor is not involved in ethanol-stimulated dopamine release in the ventral striatum of C57BL/6J mice. Alcoholism, Clinical and Experimental Research. 35: 929-38. PMID 21294756 DOI: 10.1111/j.1530-0277.2010.01423.x  1
2011 Perles-Barbacaru TA, Procissi D, Demyanenko AV, Hall FS, Uhl GR, Jacobs RE. Quantitative pharmacologic MRI: mapping the cerebral blood volume response to cocaine in dopamine transporter knockout mice. Neuroimage. 55: 622-8. PMID 21185387 DOI: 10.1016/j.neuroimage.2010.12.048  1
2011 Hall FS, Schwarzbaum JM, Perona MT, Templin JS, Caron MG, Lesch KP, Murphy DL, Uhl GR. A greater role for the norepinephrine transporter than the serotonin transporter in murine nociception. Neuroscience. 175: 315-27. PMID 21129446 DOI: 10.1016/j.neuroscience.2010.11.057  1
2011 Uhl GR, Rose JE. Individualized smoking cessation treatment: Roles for sets of genomic markers Personalized Medicine. 8: 119-121. DOI: 10.2217/pme.11.4  1
2010 Uhl GR, Drgon T, Johnson C, Ramoni MF, Behm FM, Rose JE. Genome-wide association for smoking cessation success in a trial of precessation nicotine replacement. Molecular Medicine (Cambridge, Mass.). 16: 513-26. PMID 20811658 DOI: 10.2119/molmed.2010.00052  1
2010 Ide S, Fujiwara S, Fujiwara M, Sora I, Ikeda K, Minami M, Uhl GR, Ishihara K. Antidepressant-like effect of venlafaxine is abolished in μ-opioid receptor-knockout mice. Journal of Pharmacological Sciences. 114: 107-10. PMID 20703010 DOI: JST.JSTAGE/jphs/10136SC  1
2010 Zhang X, Bearer EL, Boulat B, Hall FS, Uhl GR, Jacobs RE. Altered neurocircuitry in the dopamine transporter knockout mouse brain. Plos One. 5: e11506. PMID 20634895 DOI: 10.1371/journal.pone.0011506  1
2010 Chiocco MJ, Zhu X, Walther D, Pletnikova O, Troncoso JC, Uhl GR, Liu QR. Fine mapping of calcineurin (PPP3CA) gene reveals novel alternative splicing patterns, association of 5'UTR trinucleotide repeat with addiction vulnerability, and differential isoform expression in Alzheimer's disease. Substance Use & Misuse. 45: 1809-26. PMID 20590401 DOI: 10.3109/10826084.2010.482449  1
2010 Xu X, Mughal MR, Scott Hall F, Perona MT, Pistell PJ, Lathia JD, Chigurupati S, Becker KG, Ladenheim B, Niklason LE, Uhl GR, Cadet JL, Mattson MP. Dietary restriction mitigates cocaine-induced alterations of olfactory bulb cellular plasticity and gene expression, and behavior. Journal of Neurochemistry. 114: 323-34. PMID 20456017 DOI: 10.1111/j.1471-4159.2010.06782.x  1
2010 Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Molecular Medicine (Cambridge, Mass.). 16: 247-53. PMID 20379614 DOI: 10.2119/molmed.2009.00159  1
2010 Li CY, Zhang Y, Wang Z, Zhang Y, Cao C, Zhang PW, Lu SJ, Li XM, Yu Q, Zheng X, Du Q, Uhl GR, Liu QR, Wei L. A human-specific de novo protein-coding gene associated with human brain functions. Plos Computational Biology. 6: e1000734. PMID 20376170 DOI: 10.1371/journal.pcbi.1000734  1
2010 Uhl GR, Drgon T, Johnson C, Walther D, David SP, Aveyard P, Murphy M, Johnstone EC, Munafò MR. Genome-wide association for smoking cessation success: participants in the Patch in Practice trial of nicotine replacement. Pharmacogenomics. 11: 357-67. PMID 20235792 DOI: 10.2217/pgs.09.156  1
2010 Uhl GR. Introduction to Addiction Reviews 2. Annals of the New York Academy of Sciences. 1187: 1-2. PMID 20201843 DOI: 10.1111/j.1749-6632.2009.05418.x  1
2010 David SP, Mezuk B, Zandi PP, Strong D, Anthony JC, Niaura R, Uhl GR, Eaton WW. Sex differences in TTC12/ANKK1 haplotype associations with daily tobacco smoking in Black and White Americans. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. 12: 251-62. PMID 20133381 DOI: 10.1093/ntr/ntp201  1
2010 Drgon T, Zhang PW, Johnson C, Walther D, Hess J, Nino M, Uhl GR. Genome wide association for addiction: replicated results and comparisons of two analytic approaches. Plos One. 5: e8832. PMID 20098672 DOI: 10.1371/journal.pone.0008832  1
2010 Jones JD, Hall FS, Uhl GR, Riley AL. Dopamine, norepinephrine and serotonin transporter gene deletions differentially alter cocaine-induced taste aversion. Pharmacology, Biochemistry, and Behavior. 94: 580-7. PMID 19969013 DOI: 10.1016/j.pbb.2009.11.014  1
2010 Li B, Arime Y, Hall FS, Uhl GR, Sora I. Impaired spatial working memory and decreased frontal cortex BDNF protein level in dopamine transporter knockout mice. European Journal of Pharmacology. 628: 104-7. PMID 19932884 DOI: 10.1016/j.ejphar.2009.11.036  1
2010 Drgonova J, Zimonjic DB, Hall FS, Uhl GR. Effect of KEPI (Ppp1r14c) deletion on morphine analgesia and tolerance in mice of different genetic backgrounds: when a knockout is near a relevant quantitative trait locus. Neuroscience. 165: 882-95. PMID 19819304 DOI: 10.1016/j.neuroscience.2009.10.007  1
2010 Ide S, Sora I, Ikeda K, Minami M, Uhl GR, Ishihara K. Reduced emotional and corticosterone responses to stress in mu-opioid receptor knockout mice. Neuropharmacology. 58: 241-7. PMID 19596019 DOI: 10.1016/j.neuropharm.2009.07.005  1
2010 Scott Hall F, Sora I, Perona MTG, Uhl GR. The role of the serotonin transporter in reward mechanisms Experimental Models in Serotonin Transporter Research. 244-269. DOI: 10.1017/CBO9780511729935.009  1
2009 Uhl GR. Promise of pharmacogenomics in smoking cessation. Pharmacogenomics. 10: 1123-5. PMID 19604085 DOI: 10.2217/pgs.09.87  1
2009 Drgon T, Johnson C, Walther D, Albino AP, Rose JE, Uhl GR. Genome-wide association for smoking cessation success: participants in a trial with adjunctive denicotinized cigarettes. Molecular Medicine (Cambridge, Mass.). 15: 268-74. PMID 19593411 DOI: 10.2119/molmed.2009.00040  1
2009 Liu QR, Pan CH, Hishimoto A, Li CY, Xi ZX, Llorente-Berzal A, Viveros MP, Ishiguro H, Arinami T, Onaivi ES, Uhl GR. Species differences in cannabinoid receptor 2 (CNR2 gene): identification of novel human and rodent CB2 isoforms, differential tissue expression and regulation by cannabinoid receptor ligands. Genes, Brain, and Behavior. 8: 519-30. PMID 19496827 DOI: 10.1111/j.1601-183X.2009.00498.x  1
2009 Hall FS, Li XF, Randall-Thompson J, Sora I, Murphy DL, Lesch KP, Caron M, Uhl GR. Cocaine-conditioned locomotion in dopamine transporter, norepinephrine transporter and 5-HT transporter knockout mice. Neuroscience. 162: 870-80. PMID 19482066 DOI: 10.1016/j.neuroscience.2009.05.058  1
2009 Uhl GR, Drgon T, Li CY, Johnson C, Liu QR. Smoking and smoking cessation in disadvantaged women: assessing genetic contributions. Drug and Alcohol Dependence. 104: S58-63. PMID 19442458 DOI: 10.1016/j.drugalcdep.2009.03.012  1
2009 Hashimoto K, Amano T, Kasakura A, Uhl GR, Sora I, Sakai N, Kuzumaki N, Suzuki T, Narita M. mu-Opioid receptor-independent fashion of the suppression of sodium currents by mu-opioid analgesics in thalamic neurons. Neuroscience Letters. 453: 62-7. PMID 19429017 DOI: 10.1016/j.neulet.2009.01.066  1
2009 Saccone SF, Bierut LJ, Chesler EJ, Kalivas PW, Lerman C, Saccone NL, Uhl GR, Li CY, Philip VM, Edenberg HJ, Sherry ST, Feolo M, Moyzis RK, Rutter JL. Supplementing high-density SNP microarrays for additional coverage of disease-related genes: addiction as a paradigm. Plos One. 4: e5225. PMID 19381300 DOI: 10.1371/journal.pone.0005225  1
2009 Jones JD, Hall FS, Uhl GR, Rice K, Riley AL. Differential involvement of the norepinephrine, serotonin and dopamine reuptake transporter proteins in cocaine-induced taste aversion. Pharmacology, Biochemistry, and Behavior. 93: 75-81. PMID 19376154 DOI: 10.1016/j.pbb.2009.04.009  1
2009 Thomsen M, Hall FS, Uhl GR, Caine SB. Dramatically decreased cocaine self-administration in dopamine but not serotonin transporter knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1087-92. PMID 19176817 DOI: 10.1523/JNEUROSCI.4037-08.2009  1
2009 Uhl GR, Drgon T, Johnson C, Liu QR. Addiction genetics and pleiotropic effects of common haplotypes that make polygenic contributions to vulnerability to substance dependence. Journal of Neurogenetics. 23: 272-82. PMID 19152208 DOI: 10.1080/01677060802572929  1
2009 Johnson C, Drgon T, McMahon FJ, Uhl GR. Convergent genome wide association results for bipolar disorder and substance dependence. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 150: 182-90. PMID 19127564 DOI: 10.1002/ajmg.b.30900  1
2009 Kitanaka J, Kitanaka N, Tatsuta T, Hall FS, Uhl GR, Tanaka K, Nishiyama N, Morita Y, Takemura M. Sigma1 receptor antagonists determine the behavioral pattern of the methamphetamine-induced stereotypy in mice. Psychopharmacology. 203: 781-92. PMID 19052726 DOI: 10.1007/s00213-008-1425-z  1
2009 Drgon T, Montoya I, Johnson C, Liu QR, Walther D, Hamer D, Uhl GR. Genome-wide association for nicotine dependence and smoking cessation success in NIH research volunteers. Molecular Medicine (Cambridge, Mass.). 15: 21-7. PMID 19009022 DOI: 10.2119/molmed.2008.00096  1
2009 Li CY, Liu QR, Zhang PW, Li XM, Wei L, Uhl GR. OKCAM: an ontology-based, human-centered knowledgebase for cell adhesion molecules. Nucleic Acids Research. 37: D251-60. PMID 18790807 DOI: 10.1093/nar/gkn568  1
2009 Uhl GR, Drgon T, Johnson C, Rose JE. Nicotine abstinence genotyping: assessing the impact on smoking cessation clinical trials. The Pharmacogenomics Journal. 9: 111-5. PMID 18781146 DOI: 10.1038/tpj.2008.10  1
2009 Onaivi ES, Ishiguro H, Liu QR, Gong JP, Tagliaferro P, Brusco A, Arinami T, Uhl GR. CNS effects of CB2 cannabinoid receptors Open Neuropsychopharmacology Journal. 2: 45-52. DOI: 10.2174/1876523800902020045  1
2008 Johnson C, Drgon T, Liu QR, Zhang PW, Walther D, Li CY, Anthony JC, Ding Y, Eaton WW, Uhl GR. Genome wide association for substance dependence: convergent results from epidemiologic and research volunteer samples. Bmc Medical Genetics. 9: 113. PMID 19094236 DOI: 10.1186/1471-2350-9-113  1
2008 Uhl GR, Drgon T, Johnson C, Li CY, Contoreggi C, Hess J, Naiman D, Liu QR. Molecular genetics of addiction and related heritable phenotypes: genome-wide association approaches identify "connectivity constellation" and drug target genes with pleiotropic effects. Annals of the New York Academy of Sciences. 1141: 318-81. PMID 18991966 DOI: 10.1196/annals.1441.018  1
2008 Uhl GR. Addiction Reviews. Preface. Annals of the New York Academy of Sciences. 1141: ix-x. PMID 18991947 DOI: 10.1196/annals.1441.033  1
2008 Onaivi ES, Ishiguro H, Gong JP, Patel S, Meozzi PA, Myers L, Perchuk A, Mora Z, Tagliaferro PA, Gardner E, Brusco A, Akinshola BE, Liu QR, Chirwa SS, Hope B, ... ... Uhl GR, et al. Functional expression of brain neuronal CB2 cannabinoid receptors are involved in the effects of drugs of abuse and in depression. Annals of the New York Academy of Sciences. 1139: 434-49. PMID 18991891 DOI: 10.1196/annals.1432.036  1
2008 Onaivi ES, Carpio O, Ishiguro H, Schanz N, Uhl GR, Benno R. Behavioral effects of CB2 cannabinoid receptor activation and its influence on food and alcohol consumption. Annals of the New York Academy of Sciences. 1139: 426-33. PMID 18991890 DOI: 10.1196/annals.1432.035  1
2008 Han JC, Liu QR, Jones M, Levinn RL, Menzie CM, Jefferson-George KS, Adler-Wailes DC, Sanford EL, Lacbawan FL, Uhl GR, Rennert OM, Yanovski JA. Brain-derived neurotrophic factor and obesity in the WAGR syndrome. The New England Journal of Medicine. 359: 918-27. PMID 18753648 DOI: 10.1056/NEJMoa0801119  1
2008 Perona MT, Waters S, Hall FS, Sora I, Lesch KP, Murphy DL, Caron M, Uhl GR. Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: prominent effects of dopamine transporter deletions. Behavioural Pharmacology. 19: 566-74. PMID 18690111 DOI: 10.1097/FBP.0b013e32830cd80f  1
2008 Kitanaka N, Kitanaka J, Hall FS, Tatsuta T, Morita Y, Takemura M, Wang XB, Uhl GR. Alterations in the levels of heterotrimeric G protein subunits induced by psychostimulants, opiates, barbiturates, and ethanol: Implications for drug dependence, tolerance, and withdrawal. Synapse (New York, N.Y.). 62: 689-99. PMID 18566973 DOI: 10.1002/syn.20543  1
2008 Uhl GR, Liu QR, Drgon T, Johnson C, Walther D, Rose JE, David SP, Niaura R, Lerman C. Molecular genetics of successful smoking cessation: convergent genome-wide association study results. Archives of General Psychiatry. 65: 683-93. PMID 18519826 DOI: 10.1001/archpsyc.65.6.683  1
2008 Ide S, Minami M, Ishihara K, Uhl GR, Satoh M, Sora I, Ikeda K. Abolished thermal and mechanical antinociception but retained visceral chemical antinociception induced by butorphanol in mu-opioid receptor knockout mice. Neuropharmacology. 54: 1182-8. PMID 18417173 DOI: 10.1016/j.neuropharm.2008.03.008  1
2008 Ishiguro H, Gong JP, Hall FS, Arinami T, Uhl GR. Association of PTPRB gene polymorphism with drug addiction. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 147: 1167-72. PMID 18361428 DOI: 10.1002/ajmg.b.30742  1
2008 Uhl GR, Drgon T, Liu QR, Johnson C, Walther D, Komiyama T, Harano M, Sekine Y, Inada T, Ozaki N, Iyo M, Iwata N, Yamada M, Sora I, Chen CK, et al. Genome-wide association for methamphetamine dependence: convergent results from 2 samples. Archives of General Psychiatry. 65: 345-55. PMID 18316681 DOI: 10.1001/archpsyc.65.3.345  1
2008 Onaivi ES, Ishiguro H, Gong JP, Patel S, Meozzi PA, Myers L, Perchuk A, Mora Z, Tagliaferro PA, Gardner E, Brusco A, Akinshola BE, Hope B, Lujilde J, Inada T, ... ... Uhl GR, et al. Brain neuronal CB2 cannabinoid receptors in drug abuse and depression: from mice to human subjects. Plos One. 3: e1640. PMID 18286196 DOI: 10.1371/journal.pone.0001640  1
2008 Uhl GR, Drgon T, Johnson C, Fatusin OO, Liu QR, Contoreggi C, Li CY, Buck K, Crabbe J. "Higher order" addiction molecular genetics: convergent data from genome-wide association in humans and mice. Biochemical Pharmacology. 75: 98-111. PMID 17764662 DOI: 10.1016/j.bcp.2007.06.042  1
2007 Drgonova J, Liu QR, Hall FS, Krieger RM, Uhl GR. Deletion of v7-3 (SLC6A15) transporter allows assessment of its roles in synaptosomal proline uptake, leucine uptake and behaviors. Brain Research. 1183: 10-20. PMID 17931606 DOI: 10.1016/j.brainres.2007.09.001  1
2007 Hishimoto A, Liu QR, Drgon T, Pletnikova O, Walther D, Zhu XG, Troncoso JC, Uhl GR. Neurexin 3 polymorphisms are associated with alcohol dependence and altered expression of specific isoforms. Human Molecular Genetics. 16: 2880-91. PMID 17804423 DOI: 10.1093/hmg/ddm247  1
2007 Numachi Y, Ohara A, Yamashita M, Fukushima S, Kobayashi H, Hata H, Watanabe H, Hall FS, Lesch KP, Murphy DL, Uhl GR, Sora I. Methamphetamine-induced hyperthermia and lethal toxicity: role of the dopamine and serotonin transporters. European Journal of Pharmacology. 572: 120-8. PMID 17673199 DOI: 10.1016/j.ejphar.2007.06.022  1
2007 Yamamoto H, Kamegaya E, Hagino Y, Imai K, Fujikawa A, Tamura K, Enokiya T, Yamamoto T, Takeshima T, Koga H, Uhl GR, Ikeda K, Sora I. Genetic deletion of vesicular monoamine transporter-2 (VMAT2) reduces dopamine transporter activity in mesencephalic neurons in primary culture. Neurochemistry International. 51: 237-44. PMID 17664021 DOI: 10.1016/j.neuint.2007.06.022  1
2007 Ishiguro H, Walther D, Arinami T, Uhl GR. Variation in a bicarbonate co-transporter gene family member SLC4A7 is associated with propensity to addictions: a study using fine-mapping and three samples. Addiction (Abingdon, England). 102: 1320-5. PMID 17624982 DOI: 10.1111/j.1360-0443.2007.01877.x  1
2007 Uhl GR, Liu QR, Drgon T, Johnson C, Walther D, Rose JE. Molecular genetics of nicotine dependence and abstinence: whole genome association using 520,000 SNPs. Bmc Genetics. 8: 10. PMID 17407593 DOI: 10.1186/1471-2156-8-10  1
2007 Fukushima S, Shen H, Hata H, Ohara A, Ohmi K, Ikeda K, Numachi Y, Kobayashi H, Hall FS, Uhl GR, Sora I. Methamphetamine-induced locomotor activity and sensitization in dopamine transporter and vesicular monoamine transporter 2 double mutant mice. Psychopharmacology. 193: 55-62. PMID 17377774 DOI: 10.1007/s00213-007-0749-4  1
2007 Job MO, Tang A, Hall FS, Sora I, Uhl GR, Bergeson SE, Gonzales RA. Mu (mu) opioid receptor regulation of ethanol-induced dopamine response in the ventral striatum: evidence of genotype specific sexual dimorphic epistasis. Biological Psychiatry. 62: 627-34. PMID 17336938 DOI: 10.1016/j.biopsych.2006.11.016  1
2007 Harburg GC, Hall FS, Harrist AV, Sora I, Uhl GR, Eisch AJ. Knockout of the mu opioid receptor enhances the survival of adult-generated hippocampal granule cell neurons. Neuroscience. 144: 77-87. PMID 17055658 DOI: 10.1016/j.neuroscience.2006.09.018  1
2006 Onaivi ES, Ishiguro H, Gong JP, Patel S, Perchuk A, Meozzi PA, Myers L, Mora Z, Tagliaferro P, Gardner E, Brusco A, Akinshola BE, Liu QR, Hope B, Iwasaki S, ... ... Uhl GR, et al. Discovery of the presence and functional expression of cannabinoid CB2 receptors in brain. Annals of the New York Academy of Sciences. 1074: 514-36. PMID 17105950 DOI: 10.1196/annals.1369.052  1
2006 Liu QR, Drgon T, Johnson C, Walther D, Hess J, Uhl GR. Addiction molecular genetics: 639,401 SNP whole genome association identifies many "cell adhesion" genes. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 918-25. PMID 17099884 DOI: 10.1002/ajmg.b.30436  1
2006 Johnson C, Drgon T, Liu QR, Walther D, Edenberg H, Rice J, Foroud T, Uhl GR. Pooled association genome scanning for alcohol dependence using 104,268 SNPs: validation and use to identify alcoholism vulnerability loci in unrelated individuals from the collaborative study on the genetics of alcoholism. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 844-53. PMID 16894614 DOI: 10.1002/ajmg.b.30346  1
2006 Drgon T, D'Addario C, Uhl GR. Linkage disequilibrium, haplotype and association studies of a chromosome 4 GABA receptor gene cluster: candidate gene variants for addictions. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 141: 854-60. PMID 16894595 DOI: 10.1002/ajmg.b.30349  1
2006 Uhl GR. Molecular genetics of addiction vulnerability. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 3: 295-301. PMID 16815213 DOI: 10.1016/j.nurx.2006.05.006  1
2006 Ide S, Minami M, Ishihara K, Uhl GR, Sora I, Ikeda K. Mu opioid receptor-dependent and independent components in effects of tramadol. Neuropharmacology. 51: 651-8. PMID 16793069 DOI: 10.1016/j.neuropharm.2006.05.008  1
2006 Han W, Hata H, Imbe H, Liu QR, Takamatsu Y, Koizumi M, Murphy NP, Senba E, Uhl GR, Sora I, Ikeda K. Increased body weight in mice lacking mu-opioid receptors. Neuroreport. 17: 941-4. PMID 16738492 DOI: 10.1097/01.wnr.0000221829.87974.ad  1
2006 Drgon T, Lin Z, Wang GJ, Fowler J, Pablo J, Mash DC, Volkow N, Uhl GR. Common human 5' dopamine transporter (SLC6A3) haplotypes yield varying expression levels in vivo. Cellular and Molecular Neurobiology. 26: 875-89. PMID 16710758 DOI: 10.1007/s10571-006-9014-3  1
2006 Han W, Kasai S, Hata H, Takahashi T, Takamatsu Y, Yamamoto H, Uhl GR, Sora I, Ikeda K. Intracisternal A-particle element in the 3' noncoding region of the mu-opioid receptor gene in CXBK mice: a new genetic mechanism underlying differences in opioid sensitivity. Pharmacogenetics and Genomics. 16: 451-60. PMID 16708053 DOI: 10.1097/01.fpc.0000215072.36965.8d  1
2006 Dar DE, Metzger TG, Vandenbergh DJ, Uhl GR. Dopamine uptake and cocaine binding mechanisms: the involvement of charged amino acids from the transmembrane domains of the human dopamine transporter. European Journal of Pharmacology. 538: 43-7. PMID 16674939 DOI: 10.1016/j.ejphar.2006.03.048  1
2006 Yamada H, Shimoyama N, Sora I, Uhl GR, Fukuda Y, Moriya H, Shimoyama M. Morphine can produce analgesia via spinal kappa opioid receptors in the absence of mu opioid receptors. Brain Research. 1083: 61-9. PMID 16530171 DOI: 10.1016/j.brainres.2006.01.095  1
2006 Onaivi ES, Ishiguro H, Sejal P, Meozzi PA, Myers L, Tagliaferro P, Hope B, Leonard CM, Uhl GR, Brusco A, Gardner E. Methods to study the behavioral effects and expression of CB2 cannabinoid receptor and its gene transcripts in the chronic mild stress model of depression. Methods in Molecular Medicine. 123: 291-8. PMID 16506415  1
2006 Fride E, Perchuk A, Hall FS, Uhl GR, Onaivi ES. Behavioral methods in cannabinoid research. Methods in Molecular Medicine. 123: 269-90. PMID 16506414  1
2006 Uhl GR, Ishiguro H, Onaivi ES, Zhang PW, Akinshola BE, Lin Z, Hope B, Leonard CM, Liu QR. Molecular neurobiological methods in marijuana-cannabinoid research. Methods in Molecular Medicine. 123: 1-17. PMID 16506399  1
2006 Gong JP, Onaivi ES, Ishiguro H, Liu QR, Tagliaferro PA, Brusco A, Uhl GR. Cannabinoid CB2 receptors: immunohistochemical localization in rat brain. Brain Research. 1071: 10-23. PMID 16472786 DOI: 10.1016/j.brainres.2005.11.035  1
2006 Wu HE, Sun HS, Terashivili M, Schwasinger E, Sora I, Hall FS, Uhl GR, Tseng LF. dextro- and levo-morphine attenuate opioid delta and kappa receptor agonist produced analgesia in mu-opioid receptor knockout mice. European Journal of Pharmacology. 531: 103-7. PMID 16445907 DOI: 10.1016/j.ejphar.2005.12.012  1
2006 Yamashita M, Fukushima S, Shen HW, Hall FS, Uhl GR, Numachi Y, Kobayashi H, Sora I. Norepinephrine transporter blockade can normalize the prepulse inhibition deficits found in dopamine transporter knockout mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 2132-9. PMID 16407898 DOI: 10.1038/sj.npp.1301009  1
2006 Liu QR, Lu L, Zhu XG, Gong JP, Shaham Y, Uhl GR. Rodent BDNF genes, novel promoters, novel splice variants, and regulation by cocaine. Brain Research. 1067: 1-12. PMID 16376315 DOI: 10.1016/j.brainres.2005.10.004  1
2006 Ishiguro H, Liu QR, Gong JP, Hall FS, Ujike H, Morales M, Sakurai T, Grumet M, Uhl GR. NrCAM in addiction vulnerability: positional cloning, drug-regulation, haplotype-specific expression, and altered drug reward in knockout mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 31: 572-84. PMID 16123759 DOI: 10.1038/sj.npp.1300855  1
2006 Hall FS, Uhl GR. Transgenic mouse studies reveal substantial roles for opioid receptors in the rewarding effects of several classes of addictive drugs Current Psychiatry Reviews. 2: 27-37. DOI: 10.2174/157340006775101526  1
2005 Liu QR, Gong JP, Uhl GR. Families of protein phosphatase 1 modulators activated by protein kinases a and C: focus on brain. Progress in Nucleic Acid Research and Molecular Biology. 79: 371-404. PMID 16096033 DOI: 10.1016/S0079-6603(04)79008-X  1
2005 Liu QR, Drgon T, Walther D, Johnson C, Poleskaya O, Hess J, Uhl GR. Pooled association genome scanning: validation and use to identify addiction vulnerability loci in two samples. Proceedings of the National Academy of Sciences of the United States of America. 102: 11864-9. PMID 16091475 DOI: 10.1073/pnas.0500329102  1
2005 Dar DE, Thiruvazhi M, Abraham P, Kitayama S, Kopajtic TA, Gamliel A, Slusher BS, Carroll FI, Uhl GR. Structure-activity relationship of trihexyphenidyl analogs with respect to the dopamine transporter in the on going search for a cocaine inhibitor. European Journal of Medicinal Chemistry. 40: 1013-21. PMID 16009468 DOI: 10.1016/j.ejmech.2005.04.016  1
2005 Lin Z, Uhl GR. Proline mutations induce negative-dosage effects on uptake velocity of the dopamine transporter. Journal of Neurochemistry. 94: 276-87. PMID 15953370 DOI: 10.1111/j.1471-4159.2005.03196.x  1
2005 Dar DE, Mayo C, Uhl GR. The interaction of methylphenidate and benztropine with the dopamine transporter is different than other substrates and ligands. Biochemical Pharmacology. 70: 461-9. PMID 15950948 DOI: 10.1016/j.bcp.2005.04.032  1
2005 Ikeda K, Ide S, Han W, Hayashida M, Uhl GR, Sora I. How individual sensitivity to opiates can be predicted by gene analyses. Trends in Pharmacological Sciences. 26: 311-7. PMID 15925706 DOI: 10.1016/j.tips.2005.04.001  1
2005 Gong JP, Liu QR, Zhang PW, Wang Y, Uhl GR. Mouse brain localization of the protein kinase C-enhanced phosphatase 1 inhibitor KEPI (kinase C-enhanced PP1 inhibitor). Neuroscience. 132: 713-27. PMID 15837133 DOI: 10.1016/j.neuroscience.2004.11.052  1
2005 Lin Z, Walther D, Yu XY, Li S, Drgon T, Uhl GR. SLC18A2 promoter haplotypes and identification of a novel protective factor against alcoholism. Human Molecular Genetics. 14: 1393-404. PMID 15829504 DOI: 10.1093/hmg/ddi148  1
2005 Liu QR, Walther D, Drgon T, Polesskaya O, Lesnick TG, Strain KJ, de Andrade M, Bower JH, Maraganore DM, Uhl GR. Human brain derived neurotrophic factor (BDNF) genes, splicing patterns, and assessments of associations with substance abuse and Parkinson's Disease. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 134: 93-103. PMID 15666411 DOI: 10.1002/ajmg.b.30109  1
2004 Lin Z, Walther D, Yu XY, Drgon T, Uhl GR. The human serotonin receptor 2B: coding region polymorphisms and association with vulnerability to illegal drug abuse. Pharmacogenetics. 14: 805-11. PMID 15608559 DOI: 10.1097/00008571-200412000-00003  1
2004 Hironaka N, Ikeda K, Sora I, Uhl GR, Niki H. Food-reinforced operant behavior in dopamine transporter knockout mice: enhanced resistance to extinction. Annals of the New York Academy of Sciences. 1025: 140-5. PMID 15542711 DOI: 10.1196/annals.1316.018  1
2004 Hall FS, Sora I, Drgonova J, Li XF, Goeb M, Uhl GR. Molecular mechanisms underlying the rewarding effects of cocaine. Annals of the New York Academy of Sciences. 1025: 47-56. PMID 15542699 DOI: 10.1196/annals.1316.006  1
2004 Uhl GR. Molecular genetics of substance abuse vulnerability: remarkable recent convergence of genome scan results. Annals of the New York Academy of Sciences. 1025: 1-13. PMID 15542694 DOI: 10.1196/annals.1316.001  1
2004 Uhl GR. Molecular genetic underpinnings of human substance abuse vulnerability: likely contributions to understanding addiction as a mnemonic process. Neuropharmacology. 47: 140-7. PMID 15464133 DOI: 10.1016/j.neuropharm.2004.07.029  1
2004 Zhang PW, Ishiguro H, Ohtsuki T, Hess J, Carillo F, Walther D, Onaivi ES, Arinami T, Uhl GR. Human cannabinoid receptor 1: 5' exons, candidate regulatory regions, polymorphisms, haplotypes and association with polysubstance abuse. Molecular Psychiatry. 9: 916-31. PMID 15289816 DOI: 10.1038/sj.mp.4001560  1
2004 Shen HW, Hagino Y, Kobayashi H, Shinohara-Tanaka K, Ikeda K, Yamamoto H, Yamamoto T, Lesch KP, Murphy DL, Hall FS, Uhl GR, Sora I. Regional differences in extracellular dopamine and serotonin assessed by in vivo microdialysis in mice lacking dopamine and/or serotonin transporters. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1790-9. PMID 15226739 DOI: 10.1038/sj.npp.1300476  1
2004 Berrettini W, Bierut L, Crowley TJ, Cubells JF, Frascella J, Gelernter J, Hewitt JK, Kreek MJ, Lachman H, Leppert M, Li MD, Madden P, Miner C, Pollock JD, Pomerleau O, ... ... Uhl GR, et al. Setting priorities for genomic research. Science (New York, N.Y.). 304: 1445-7; author reply. PMID 15178784 DOI: 10.1126/science.304.5676.1445c  1
2004 Dohi T, Kitayama S, Morioka N, Kumagai K, Mitsuhata C, Morita K, Kozai K, Lin Z, Uhl GR. Regulation of dopamine and MPP+ transport by catecholamine transporters. Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. 24: 43-7. PMID 15164608  1
2004 Ide S, Minami M, Satoh M, Uhl GR, Sora I, Ikeda K. Buprenorphine antinociception is abolished, but naloxone-sensitive reward is retained, in mu-opioid receptor knockout mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1656-63. PMID 15100703 DOI: 10.1038/sj.npp.1300463  1
2004 Uhl GR, Grow RW. The burden of complex genetics in brain disorders. Archives of General Psychiatry. 61: 223-9. PMID 14993109 DOI: 10.1001/archpsyc.61.3.223  1
2004 Hall FS, Goeb M, Li XF, Sora I, Uhl GR. mu-Opioid receptor knockout mice display reduced cocaine conditioned place preference but enhanced sensitization of cocaine-induced locomotion. Brain Research. Molecular Brain Research. 121: 123-30. PMID 14969743 DOI: 10.1016/j.molbrainres.2003.10.024  1
2004 Liu QR, Zhang PW, Lin Z, Li QF, Woods AS, Troncoso J, Uhl GR. GBPI, a novel gastrointestinal- and brain-specific PP1-inhibitory protein, is activated by PKC and inactivated by PKA. The Biochemical Journal. 377: 171-81. PMID 12974676 DOI: 10.1042/BJ20030128  1
2004 Hall ES, Sora I, Uhl GR. Molecular mechanisms underlying behavioral effects of cocaine: Lessons from knockout mice Current Pharmacogenomics. 2: 185-202. DOI: 10.2174/1570160043377673  1
2003 Mizoguchi H, Wu HE, Narita M, Sora I, Hall SF, Uhl GR, Loh HH, Nagase H, Tseng LF. Lack of mu-opioid receptor-mediated G-protein activation in the spinal cord of mice lacking Exon 1 or Exons 2 and 3 of the MOR-1 gene. Journal of Pharmacological Sciences. 93: 423-9. PMID 14737012 DOI: 10.1254/jphs.93.423  1
2003 Murphy DL, Uhl GR, Holmes A, Ren-Patterson R, Hall FS, Sora I, Detera-Wadleigh S, Lesch KP. Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders. Genes, Brain, and Behavior. 2: 350-64. PMID 14653307 DOI: 10.1046/j.1601-1848.2003.00049.x  1
2003 Kitanaka N, Kitanaka J, Walther D, Wang XB, Uhl GR. Comparative inter-strain sequence analysis of the putative regulatory region of murine psychostimulant-regulated gene GNB1 (G protein beta 1 subunit gene). Dna Sequence : the Journal of Dna Sequencing and Mapping. 14: 257-63. PMID 14631649 DOI: 10.1080/1042517031000149048  1
2003 Uhl GR, Lin Z. The top 20 dopamine transporter mutants: structure-function relationships and cocaine actions. European Journal of Pharmacology. 479: 71-82. PMID 14612139 DOI: 10.1016/j.ejphar.2003.08.058  1
2003 Uhl GR. Dopamine transporter: basic science and human variation of a key molecule for dopaminergic function, locomotion, and parkinsonism. Movement Disorders : Official Journal of the Movement Disorder Society. 18: S71-80. PMID 14531049 DOI: 10.1002/mds.10578  1
2003 Hall FS, Li XF, Goeb M, Roff S, Hoggatt H, Sora I, Uhl GR. Congenic C57BL/6 mu opiate receptor (MOR) knockout mice: baseline and opiate effects. Genes, Brain, and Behavior. 2: 114-21. PMID 12884968 DOI: 10.1034/j.1601-183X.2003.00016.x  1
2003 Lin Z, Uhl GR. Human dopamine transporter gene variation: effects of protein coding variants V55A and V382A on expression and uptake activities. The Pharmacogenomics Journal. 3: 159-68. PMID 12815364 DOI: 10.1038/sj.tpj.6500169  1
2003 Uhl GR. Are over-simplified views of addiction neuroscience providing too simplified ethical considerations? Addiction (Abingdon, England). 98: 872-3. PMID 12814491 DOI: 10.1046/j.1360-0443.2003.00453.x  1
2003 Hall FS, Drgonova J, Goeb M, Uhl GR. Reduced behavioral effects of cocaine in heterozygous brain-derived neurotrophic factor (BDNF) knockout mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 1485-90. PMID 12784114 DOI: 10.1038/sj.npp.1300192  1
2003 Uhl GR. Needed: mouse/human cross validation of reinstatement/relapse models (and drug reward models) to model human substance abuse vulnerability allelic variants. Psychopharmacology. 168: 42-3. PMID 12719965 DOI: 10.1007/s00213-003-1499-6  1
2003 Lin Z, Zhang PW, Zhu X, Melgari JM, Huff R, Spieldoch RL, Uhl GR. Phosphatidylinositol 3-kinase, protein kinase C, and MEK1/2 kinase regulation of dopamine transporters (DAT) require N-terminal DAT phosphoacceptor sites. The Journal of Biological Chemistry. 278: 20162-70. PMID 12660249 DOI: 10.1074/jbc.M209584200  1
2003 Hall FS, Sora I, Uhl GR. Sex-dependent modulation of ethanol consumption in vesicular monoamine transporter 2 (VMAT2) and dopamine transporter (DAT) knockout mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 620-8. PMID 12655306 DOI: 10.1038/sj.npp.1300070  1
2003 Wisor JP, Wurts SW, Hall FS, Lesch KP, Murphy DL, Uhl GR, Edgar DM. Altered rapid eye movement sleep timing in serotonin transporter knockout mice. Neuroreport. 14: 233-8. PMID 12598736 DOI: 10.1097/01.wnr.0000054963.21656.bf  1
2003 Sokolov BP, Polesskaya OO, Uhl GR. Mouse brain gene expression changes after acute and chronic amphetamine. Journal of Neurochemistry. 84: 244-52. PMID 12558987 DOI: 10.1046/j.1471-4159.2003.01523.x  1
2002 Itokawa M, Lin Z, Uhl GR. Dopamine efflux via wild-type and mutant dopamine transporters: alanine substitution for proline-572 enhances efflux and reduces dependence on extracellular dopamine, sodium and chloride concentrations. Brain Research. Molecular Brain Research. 108: 71-80. PMID 12480180 DOI: 10.1016/S0169-328X(02)00515-6  1
2002 Mizoguchi H, Wu HE, Narita M, Hall FS, Sora I, Uhl GR, Nagase H, Tseng LF. Antagonistic property of buprenorphine for putative epsilon-opioid receptor-mediated G-protein activation by beta-endorphin in pons/medulla of the mu-opioid receptor knockout mouse. Neuroscience. 115: 715-21. PMID 12435410 DOI: 10.1016/S0306-4522(02)00486-4  1
2002 Hall FS, Li XF, Sora I, Xu F, Caron M, Lesch KP, Murphy DL, Uhl GR. Cocaine mechanisms: enhanced cocaine, fluoxetine and nisoxetine place preferences following monoamine transporter deletions. Neuroscience. 115: 153-61. PMID 12401330 DOI: 10.1016/S0306-4522(02)00379-2  1
2002 Kitanaka J, Kitanaka N, Takemura M, Wang XB, Hembree CM, Goodman NL, Uhl GR. Isolation and sequencing of a putative promoter region of the murine G protein beta 1 subunit (GNB1) gene. Dna Sequence : the Journal of Dna Sequencing and Mapping. 13: 39-45. PMID 12180136 DOI: 10.1080/10425170290019883  1
2002 Uhl GR, Liu QR, Naiman D. Substance abuse vulnerability loci: converging genome scanning data. Trends in Genetics : Tig. 18: 420-5. PMID 12142011 DOI: 10.1016/S0168-9525(02)02719-1  1
2002 Zhou Y, Spangler R, Schlussman SD, Yuferov VP, Sora I, Ho A, Uhl GR, Kreek MJ. Effects of acute "binge" cocaine on preprodynorphin, preproenkephalin, proopiomelanocortin, and corticotropin-releasing hormone receptor mRNA levels in the striatum and hypothalamic-pituitary-adrenal axis of mu-opioid receptor knockout mice. Synapse (New York, N.Y.). 45: 220-9. PMID 12125043 DOI: 10.1002/syn.10101  1
2002 Albin RL, Nichols TE, Frey KA. Brain imaging to assess the effects of dopamine agonists on progression of Parkinson disease. Jama. 288: 311-2; author reply . PMID 12117386  1
2002 Onaivi ES, Leonard CM, Ishiguro H, Zhang PW, Lin Z, Akinshola BE, Uhl GR. Endocannabinoids and cannabinoid receptor genetics. Progress in Neurobiology. 66: 307-44. PMID 12015198 DOI: 10.1016/S0301-0082(02)00007-2  1
2002 Lin Z, Uhl GR. Dopamine transporter mutants with cocaine resistance and normal dopamine uptake provide targets for cocaine antagonism. Molecular Pharmacology. 61: 885-91. PMID 11901228 DOI: 10.1124/mol.61.4.885  1
2002 Liu QR, Zhang PW, Zhen Q, Walther D, Wang XB, Uhl GR. KEPI, a PKC-dependent protein phosphatase 1 inhibitor regulated by morphine. The Journal of Biological Chemistry. 277: 13312-20. PMID 11812771 DOI: 10.1074/jbc.M107558200  1
2002 Uhl GR, Hall FS, Sora I. Cocaine, reward, movement and monoamine transporters. Molecular Psychiatry. 7: 21-6. PMID 11803442 DOI: 10.1038/sj/mp/4000964  1
2001 Kitanaka J, Wang XB, Kitanaka N, Hembree CM, Uhl GR. Genomic organization of the murine G protein beta subunit genes and related processed pseudogenes. Dna Sequence : the Journal of Dna Sequencing and Mapping. 12: 345-54. PMID 11913780 DOI: 10.3109/10425170109084458  1
2001 Uhl GR, Liu QR, Walther D, Hess J, Naiman D. Polysubstance abuse-vulnerability genes: genome scans for association, using 1,004 subjects and 1,494 single-nucleotide polymorphisms. American Journal of Human Genetics. 69: 1290-300. PMID 11704927 DOI: 10.1086/324467  1
2001 Persico AM, Mengual E, Moessner R, Hall FS, Revay RS, Sora I, Arellano J, DeFelipe J, Gimenez-Amaya JM, Conciatori M, Marino R, Baldi A, Cabib S, Pascucci T, Uhl GR, et al. Barrel pattern formation requires serotonin uptake by thalamocortical afferents, and not vesicular monoamine release. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6862-73. PMID 11517274  1
2001 Sora I, Elmer G, Funada M, Pieper J, Li XF, Hall FS, Uhl GR. Mu opiate receptor gene dose effects on different morphine actions: evidence for differential in vivo mu receptor reserve. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 25: 41-54. PMID 11377918 DOI: 10.1016/S0893-133X(00)00252-9  1
2001 Sora I, Hall FS, Andrews AM, Itokawa M, Li XF, Wei HB, Wichems C, Lesch KP, Murphy DL, Uhl GR. Molecular mechanisms of cocaine reward: combined dopamine and serotonin transporter knockouts eliminate cocaine place preference. Proceedings of the National Academy of Sciences of the United States of America. 98: 5300-5. PMID 11320258 DOI: 10.1073/pnas.091039298  1
2001 Hall FS, Sora I, Uhl GR. Ethanol consumption and reward are decreased in mu-opiate receptor knockout mice. Psychopharmacology. 154: 43-9. PMID 11292005 DOI: 10.1007/s002130000622  1
2000 Uhl GR, Li S, Takahashi N, Itokawa K, Lin Z, Hazama M, Sora I. The VMAT2 gene in mice and humans: amphetamine responses, locomotion, cardiac arrhythmias, aging, and vulnerability to dopaminergic toxins. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 14: 2459-65. PMID 11099463 DOI: 10.1096/fj.00-0205rev  1
2000 Lin Z, Wang W, Uhl GR. Dopamine transporter tryptophan mutants highlight candidate dopamine- and cocaine-selective domains. Molecular Pharmacology. 58: 1581-92. PMID 11093799  1
2000 Vandenbergh DJ, Rodriguez LA, Hivert E, Schiller JH, Villareal G, Pugh EW, Lachman H, Uhl GR. Long forms of the dopamine receptor (DRD4) gene VNTR are more prevalent in substance abusers: no interaction with functional alleles of the catechol-o-methyltransferase (COMT) gene. American Journal of Medical Genetics. 96: 678-83. PMID 11054777 DOI: 10.1002/1096-8628(20001009)96:5<678::AID-AJMG15>3.0.CO;2-8  1
2000 Vandenbergh DJ, Thompson MD, Cook EH, Bendahhou E, Nguyen T, Krasowski MD, Zarrabian D, Comings D, Sellers EM, Tyndale RF, George SR, O'Dowd BF, Uhl GR. Human dopamine transporter gene: coding region conservation among normal, Tourette's disorder, alcohol dependence and attention-deficit hyperactivity disorder populations. Molecular Psychiatry. 5: 283-92. PMID 10889531  1
2000 LaBuda CJ, Sora I, Uhl GR, Fuchs PN. Stress-induced analgesia in mu-opioid receptor knockout mice reveals normal function of the delta-opioid receptor system. Brain Research. 869: 1-5. PMID 10865052 DOI: 10.1016/S0006-8993(00)02196-X  1
2000 Itokawa M, Lin Z, Cai NS, Wu C, Kitayama S, Wang JB, Uhl GR. Dopamine transporter transmembrane domain polar mutants: DeltaG and DeltaDeltaG values implicate regions important for transporter functions. Molecular Pharmacology. 57: 1093-103. PMID 10825379  0.6
2000 Deng HB, Yu Y, Pak Y, O'Dowd BF, George SR, Surratt CK, Uhl GR, Wang JB. Role for the C-terminus in agonist-induced mu opioid receptor phosphorylation and desensitization. Biochemistry. 39: 5492-9. PMID 10820022 DOI: 10.1021/bi991938b  1
2000 Hosohata Y, Vanderah TW, Burkey TH, Ossipov MH, Kovelowski CJ, Sora I, Uhl GR, Zhang X, Rice KC, Roeske WR, Hruby VJ, Yamamura HI, Lai J, Porreca F. delta-Opioid receptor agonists produce antinociception and [35S]GTPgammaS binding in mu receptor knockout mice. European Journal of Pharmacology. 388: 241-8. PMID 10675732 DOI: 10.1016/S0014-2999(99)00897-3  1
1999 Donovan DM, Miner LL, Perry MP, Revay RS, Sharpe LG, Przedborski S, Kostic V, Philpot RM, Kirstein CL, Rothman RB, Schindler CW, Uhl GR. Cocaine reward and MPTP toxicity: alteration by regional variant dopamine transporter overexpression. Brain Research. Molecular Brain Research. 73: 37-49. PMID 10581396 DOI: 10.1016/S0169-328X(99)00235-1  1
1999 Garzón M, Vaughan RA, Uhl GR, Kuhar MJ, Pickel VM. Cholinergic axon terminals in the ventral tegmental area target a subpopulation of neurons expressing low levels of the dopamine transporter. The Journal of Comparative Neurology. 410: 197-210. PMID 10414527 DOI: 10.1002/(SICI)1096-9861(19990726)410:2<197::AID-CNE3>3.0.CO;2-D  1
1998 Kitayama S, Mitsuhata C, Davis S, Wang JB, Sato T, Morita K, Uhl GR, Dohi T. MPP+ toxicity and plasma membrane dopamine transporter: study using cell lines expressing the wild-type and mutant rat dopamine transporters. Biochimica Et Biophysica Acta. 1404: 305-13. PMID 9739158  0.6
1998 Mitsuhata C, Kitayama S, Morita K, Vandenbergh D, Uhl GR, Dohi T. Tyrosine-533 of rat dopamine transporter: involvement in interactions with 1-methyl-4-phenylpyridinium and cocaine. Brain Research. Molecular Brain Research. 56: 84-8. PMID 9602072 DOI: 10.1016/S0169-328X(98)00032-1  1
1998 Persico AM, Reich S, Henningfield JE, Kuhar MJ, Uhl GR. Parkinsonian patients report blunted subjective effects of methylphenidate. Experimental and Clinical Psychopharmacology. 6: 54-63. PMID 9526146 DOI: 10.1037/1064-1297.6.1.54  1
1998 Rothman RB, Silverthorn ML, Glowa JR, Matecka D, Rice KC, Carroll FI, Partilla JS, Uhl GR, Vandenbergh DJ, Dersch CM. Studies of the biogenic amine transporters. VII. Characterization of a novel cocaine binding site identified with [125I]RTI-55 in membranes prepared from human, monkey and guinea pig caudate. Synapse (New York, N.Y.). 28: 322-38. PMID 9517841 DOI: 10.1002/(SICI)1098-2396(199804)28:4<322::AID-SYN8>3.0.CO;2-B  1
1998 Vaughan RA, Huff RA, Uhl GR, Kuhar MJ. Phosphorylation of dopamine transporters and rapid adaptation to cocaine. Advances in Pharmacology (San Diego, Calif.). 42: 1042-5. PMID 9328076 DOI: 10.1016/S1054-3589(08)60925-4  1
1998 Uhl GR, Vandenbergh DJ, Rodriguez LA, Miner L, Takahashi N. Dopaminergic genes and substance abuse. Advances in Pharmacology (San Diego, Calif.). 42: 1024-32. PMID 9328073 DOI: 10.1016/S1054-3589(08)60922-9  1
1997 Vandenbergh DJ, Zonderman AB, Wang J, Uhl GR, Costa PT. No association between novelty seeking and dopamine D4 receptor (D4DR) exon III seven repeat alleles in Baltimore Longitudinal Study of Aging participants. Molecular Psychiatry. 2: 417-9. PMID 9322238  1
1997 Wang H, Moriwaki A, Wang JB, Uhl GR, Pickel VM. Ultrastructural immunocytochemical localization of mu-opioid receptors in dendritic targets of dopaminergic terminals in the rat caudate-putamen nucleus. Neuroscience. 81: 757-71. PMID 9316027 DOI: 10.1016/S0306-4522(97)00253-4  1
1997 Nirenberg MJ, Chan J, Pohorille A, Vaughan RA, Uhl GR, Kuhar MJ, Pickel VM. The dopamine transporter: comparative ultrastructure of dopaminergic axons in limbic and motor compartments of the nucleus accumbens. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 6899-907. PMID 9278525  1
1997 Takahashi N, Miner LL, Sora I, Ujike H, Revay RS, Kostic V, Jackson-Lewis V, Przedborski S, Uhl GR. VMAT2 knockout mice: heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity. Proceedings of the National Academy of Sciences of the United States of America. 94: 9938-43. PMID 9275230 DOI: 10.1073/pnas.94.18.9938  1
1997 Wang XB, Funada M, Imai Y, Revay RS, Ujike H, Vandenbergh DJ, Uhl GR. rGbeta1: a psychostimulant-regulated gene essential for establishing cocaine sensitization. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 5993-6000. PMID 9221795  1
1997 Vaughan RA, Huff RA, Uhl GR, Kuhar MJ. Protein kinase C-mediated phosphorylation and functional regulation of dopamine transporters in striatal synaptosomes. The Journal of Biological Chemistry. 272: 15541-6. PMID 9182590 DOI: 10.1074/jbc.272.24.15541  1
1997 Nirenberg MJ, Chan J, Vaughan RA, Uhl GR, Kuhar MJ, Pickel VM. Immunogold localization of the dopamine transporter: an ultrastructural study of the rat ventral tegmental area. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 4037-44. PMID 9151720  1
1997 Uhl GR, Gold LH, Risch N. Genetic analyses of complex behavioral disorders. Proceedings of the National Academy of Sciences of the United States of America. 94: 2785-6. PMID 9096294 DOI: 10.1073/pnas.94.7.2785  1
1997 Kaddis FG, Clarkson ED, Weber MJ, Vandenbergh DJ, Donovan DM, Mallet J, Horellou P, Uhl GR, Freed CR. Intrastriatal grafting of Cos cells stably expressing human aromatic L-amino acid decarboxylase: neurochemical effects. Journal of Neurochemistry. 68: 1520-6. PMID 9084422  1
1997 Huff RA, Vaughan RA, Kuhar MJ, Uhl GR. Phorbol esters increase dopamine transporter phosphorylation and decrease transport Vmax. Journal of Neurochemistry. 68: 225-32. PMID 8978729  1
1996 Kitayama S, Morita K, Dohi T, Wang JB, Davis SC, Uhl GR. Dissection of dopamine and cocaine binding sites on the rat dopamine transporter expressed in COS cells. Annals of the New York Academy of Sciences. 801: 388-93. PMID 8959052  0.6
1996 Van Bockstaele EJ, Colago EE, Moriwaki A, Uhl GR. Mu-opioid receptor is located on the plasma membrane of dendrites that receive asymmetric synapses from axon terminals containing leucine-enkephalin in the rat nucleus locus coeruleus. The Journal of Comparative Neurology. 376: 65-74. PMID 8946284 DOI: 10.1002/(SICI)1096-9861(19961202)376:1<65::AID-CNE4>3.0.CO;2-M  1
1996 Wang H, Moriwaki A, Wang JB, Uhl GR, Pickel VM. Ultrastructural immunocytochemical localization of mu opioid receptors and Leu5-enkephalin in the patch compartment of the rat caudate-putamen nucleus. The Journal of Comparative Neurology. 375: 659-74. PMID 8930791 DOI: 10.1002/(SICI)1096-9861(19961125)375:4<659::AID-CNE7>3.0.CO;2-0  1
1996 Cheng PY, Moriwaki A, Wang JB, Uhl GR, Pickel VM. Ultrastructural localization of mu-opioid receptors in the superficial layers of the rat cervical spinal cord: extrasynaptic localization and proximity to Leu5-enkephalin. Brain Research. 731: 141-54. PMID 8883864 DOI: 10.1016/S0006-8993(96)00492-1  1
1996 Uhl GR, Vandenbergh DJ, Miner LL. Knockout mice and dirty drugs. Drug addiction. Current Biology : Cb. 6: 935-6. PMID 8805320 DOI: 10.1016/S0960-9822(02)00630-9  1
1996 Van Bockstaele EJ, Colago EE, Cheng P, Moriwaki A, Uhl GR, Pickel VM. Ultrastructural evidence for prominent distribution of the mu-opioid receptor at extrasynaptic sites on noradrenergic dendrites in the rat nucleus locus coeruleus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 5037-48. PMID 8756434  1
1996 Inoue K, Sato K, Tohyama M, Shimada S, Uhl GR. Widespread brain distribution of mRNA encoding the orphan neurotransmitter transporter v7-3. Brain Research. Molecular Brain Research. 37: 217-23. PMID 8738154  0.6
1996 Zhang L, Yu Y, Mackin S, Weight FF, Uhl GR, Wang JB. Differential mu opiate receptor phosphorylation and desensitization induced by agonists and phorbol esters. The Journal of Biological Chemistry. 271: 11449-54. PMID 8626702 DOI: 10.1074/jbc.271.19.11449  1
1996 Donovan DM, Miner LL, Sharpe L, Cho HJ, Takemura M, Unterwald E, Nyberg F, Kreek MJ, Uhl GR. Transgenic mice: preproenkephalin and the mu opiate receptor. Annals of the New York Academy of Sciences. 780: 19-28. PMID 8602733 DOI: 10.1111/j.1749-6632.1996.tb15108.x  1
1996 Nirenberg MJ, Vaughan RA, Uhl GR, Kuhar MJ, Pickel VM. The dopamine transporter is localized to dendritic and axonal plasma membranes of nigrostriatal dopaminergic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 436-47. PMID 8551328  1
1995 Unterwald EM, Rubenfeld JM, Imai Y, Wang JB, Uhl GR, Kreek MJ. Chronic opioid antagonist administration upregulates mu opioid receptor binding without altering mu opioid receptor mRNA levels. Brain Research. Molecular Brain Research. 33: 351-5. PMID 8750897 DOI: 10.1016/0169-328X(95)00143-G  1
1995 Persico AM, Schindler CW, Zaczek R, Brannock MT, Uhl GR. Brain transcription factor gene expression, neurotransmitter levels, and novelty response behaviors: alterations during rat amphetamine withdrawal and following chronic injection stress. Synapse (New York, N.Y.). 19: 212-27. PMID 7784961 DOI: 10.1002/syn.890190309  0.44
1995 Patel A, Rochelle JM, Jones JM, Sumegi J, Uhl GR, Seldin MF, Meisler MH, Gregor P. Mapping of the taurine transporter gene to mouse chromosome 6 and to the short arm of human chromosome 3. Genomics. 25: 314-7. PMID 7774940 DOI: 10.1016/0888-7543(95)80146-D  1
1995 Donovan DM, Vandenbergh DJ, Perry MP, Bird GS, Ingersoll R, Nanthakumar E, Uhl GR. Human and mouse dopamine transporter genes: conservation of 5'-flanking sequence elements and gene structures. Brain Research. Molecular Brain Research. 30: 327-35. PMID 7637582 DOI: 10.1016/0169-328X(95)00018-N  1
1995 Freed C, Revay R, Vaughan RA, Kriek E, Grant S, Uhl GR, Kuhar MJ. Dopamine transporter immunoreactivity in rat brain. The Journal of Comparative Neurology. 359: 340-9. PMID 7499533 DOI: 10.1002/cne.903590211  1
1994 Lossie AC, Vandenbergh DJ, Uhl GR, Camper SA. Localization of the dopamine transporter gene, Dat1, on mouse chromosome 13. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 5: 117-8. PMID 8180472 DOI: 10.1007/BF00292340  1
1994 Gonzalez AM, Uhl GR. 'Choline/orphan V8-2-1/creatine transporter' mRNA is expressed in nervous, renal and gastrointestinal systems. Brain Research. Molecular Brain Research. 23: 266-70. PMID 8057783 DOI: 10.1016/0169-328X(94)90233-X  1
1994 Gregor P, Gaston SM, Yang X, O'Regan JP, Rosen DR, Tanzi RE, Patterson D, Haines JL, Horvitz HR, Uhl GR. Genetic and physical mapping of the GLUR5 glutamate receptor gene on human chromosome 21. Human Genetics. 94: 565-70. PMID 7959697 DOI: 10.1007/BF00211029  1
1994 Kitayama S, Dohi T, Uhl GR. Phorbol esters alter functions of the expressed dopamine transporter. European Journal of Pharmacology. 268: 115-9. PMID 7957633  0.6
1994 Gonzalez AM, Walther D, Pazos A, Uhl GR. Synaptic vesicular monoamine transporter expression: distribution and pharmacologic profile. Brain Research. Molecular Brain Research. 22: 219-26. PMID 7912402 DOI: 10.1016/0169-328X(94)90050-7  1
1994 Wang JB, Johnson PS, Persico AM, Hawkins AL, Griffin CA, Uhl GR. Human mu opiate receptor. cDNA and genomic clones, pharmacologic characterization and chromosomal assignment. Febs Letters. 338: 217-22. PMID 7905839 DOI: 10.1016/0014-5793(94)80368-4  1
1993 Gregor P, Patel A, Shimada S, Lin CL, Rochelle JM, Kitayama S, Seldin MF, Uhl GR. Murine serotonin transporter: sequence and localization to chromosome 11. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 4: 283-4. PMID 8507984 DOI: 10.1007/BF00417438  1
1993 Cerruti C, Walther DM, Kuhar MJ, Uhl GR. Dopamine transporter mRNA expression is intense in rat midbrain neurons and modest outside midbrain. Brain Research. Molecular Brain Research. 18: 181-6. PMID 8479287 DOI: 10.1016/0169-328X(93)90187-T  1
1993 Gregor P, Reeves RH, Jabs EW, Yang X, Dackowski W, Rochelle JM, Brown RH, Haines JL, O'Hara BF, Uhl GR. Chromosomal localization of glutamate receptor genes: relationship to familial amyotrophic lateral sclerosis and other neurological disorders of mice and humans. Proceedings of the National Academy of Sciences of the United States of America. 90: 3053-7. PMID 8464923  1
1993 Fujita M, Shimada S, Nishimura T, Uhl GR, Tohyama M. Ontogeny of dopamine transporter mRNA expression in the rat brain. Brain Research. Molecular Brain Research. 19: 222-6. PMID 8412565  0.6
1993 Persico AM, Vandenbergh DJ, Smith SS, Uhl GR. Dopamine transporter gene polymorphisms are not associated with polysubstance abuse. Biological Psychiatry. 34: 265-7. PMID 8399824 DOI: 10.1016/0006-3223(93)90081-N  1
1993 Kusama T, Spivak CE, Whiting P, Dawson VL, Schaeffer JC, Uhl GR. Pharmacology of GABA rho 1 and GABA alpha/beta receptors expressed in Xenopus oocytes and COS cells. British Journal of Pharmacology. 109: 200-6. PMID 8388298 DOI: 10.1111/j.1476-5381.1993.tb13554.x  1
1993 Uhl GR, Kitayama S. A cloned dopamine transporter. Potential insights into Parkinson's disease pathogenesis. Advances in Neurology. 60: 321-4. PMID 8380524  0.6
1993 Kitayama S, Wang JB, Uhl GR. Dopamine transporter mutants selectively enhance MPP+ transport. Synapse (New York, N.Y.). 15: 58-62. PMID 8310426 DOI: 10.1002/syn.890150107  0.6
1993 Gregor P, O'Hara BF, Yang X, Uhl GR. Expression and novel subunit isoforms of glutamate receptor genes GluR5 and GluR6. Neuroreport. 4: 1343-6. PMID 8260617  0.32
1993 Persico AM, Schindler CW, O'Hara BF, Brannock MT, Uhl GR. Brain transcription factor expression: effects of acute and chronic amphetamine and injection stress. Brain Research. Molecular Brain Research. 20: 91-100. PMID 8255186 DOI: 10.1016/0169-328X(93)90113-4  1
1993 Wang JB, Imai Y, Eppler CM, Gregor P, Spivak CE, Uhl GR. mu opiate receptor: cDNA cloning and expression. Proceedings of the National Academy of Sciences of the United States of America. 90: 10230-4. PMID 8234282  0.32
1993 Dawson VL, Dawson TM, Uhl GR, Snyder SH. Human immunodeficiency virus type 1 coat protein neurotoxicity mediated by nitric oxide in primary cortical cultures. Proceedings of the National Academy of Sciences of the United States of America. 90: 3256-9. PMID 8097316  1
1993 Persico AM, O'Hara BF, Farmer S, Gysin R, Flanagan SD, Uhl GR. Dopamine D2 receptor gene Taq I 'A' locus map including 'A4' variant: relevance for alcoholism and drug abuse. Drug and Alcohol Dependence. 31: 229-34. PMID 8096458 DOI: 10.1016/0376-8716(93)90005-B  1
1993 Persico AM, Schindler CW, Brannock MT, Gonzalez AM, Surratt CK, Uhl GR. Dopaminergic gene expression during amphetamine withdrawal. Neuroreport. 4: 41-4. PMID 8095821  1
1993 Surratt CK, Persico AM, Yang XD, Edgar SR, Bird GS, Hawkins AL, Griffin CA, Li X, Jabs EW, Uhl GR. A human synaptic vesicle monoamine transporter cDNA predicts posttranslational modifications, reveals chromosome 10 gene localization and identifies TaqI RFLPs. Febs Letters. 318: 325-30. PMID 8095030 DOI: 10.1016/0014-5793(93)80539-7  1
1993 Surratt CK, Wang JB, Yuhasz S, Amzel M, Kwon HM, Handler JS, Uhl GR. Sodium- and chloride-dependent transporters in brain, kidney, and gut: lessons from complementary DNA cloning and structure-function studies. Current Opinion in Nephrology and Hypertension. 2: 744-60. PMID 7922216  1
1993 Dawson TM, Steiner JP, Dawson VL, Dinerman JL, Uhl GR, Snyder SH. Immunosuppressant FK506 enhances phosphorylation of nitric oxide synthase and protects against glutamate neurotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 90: 9808-12. PMID 7694293 DOI: 10.1073/pnas.90.21.9808  1
1993 Dawson VL, Dawson TM, Bartley DA, Uhl GR, Snyder SH. Mechanisms of nitric oxide-mediated neurotoxicity in primary brain cultures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 2651-61. PMID 7684776  1
1992 Kitayama S, Shimada S, Uhl GR. Parkinsonism-inducing neurotoxin MPP+: uptake and toxicity in nonneuronal COS cells expressing dopamine transporter cDNA. Annals of Neurology. 32: 109-11. PMID 1642464 DOI: 10.1002/ana.410320120  0.6
1992 Kitayama S, Shimada S, Xu H, Markham L, Donovan DM, Uhl GR. Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding. Proceedings of the National Academy of Sciences of the United States of America. 89: 7782-5. PMID 1502198  0.6
1992 Vandenbergh DJ, Persico AM, Hawkins AL, Griffin CA, Li X, Jabs EW, Uhl GR. Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR. Genomics. 14: 1104-6. PMID 1478653 DOI: 10.1016/S0888-7543(05)80138-7  1
1992 Durand GM, Gregor P, Zheng X, Bennett MV, Uhl GR, Zukin RS. Cloning of an apparent splice variant of the rat N-methyl-D-aspartate receptor NMDAR1 with altered sensitivity to polyamines and activators of protein kinase C. Proceedings of the National Academy of Sciences of the United States of America. 89: 9359-63. PMID 1409641  1
1992 Uhl GR, Kitayama S, Gregor P, Nanthakumar E, Persico A, Shimada S. Neurotransmitter transporter family cDNAs in a rat midbrain library: 'orphan transporters' suggest sizable structural variations. Brain Research. Molecular Brain Research. 16: 353-9. PMID 1363329  0.6
1992 Vandenbergh DJ, Persico AM, Uhl GR. A human dopamine transporter cDNA predicts reduced glycosylation, displays a novel repetitive element and provides racially-dimorphic TaqI RFLPs. Brain Research. Molecular Brain Research. 15: 161-6. PMID 1359373 DOI: 10.1016/0169-328X(92)90165-8  1
1992 Smith SS, O'Hara BF, Persico AM, Gorelick DA, Newlin DB, Vlahov D, Solomon L, Pickens R, Uhl GR. Genetic vulnerability to drug abuse. The D2 dopamine receptor Taq I B1 restriction fragment length polymorphism appears more frequently in polysubstance abusers. Archives of General Psychiatry. 49: 723-7. PMID 1355337 DOI: 10.1001/archpsyc.1992.01820090051009  1
1992 Gregor P, Yang X, Mano I, Takemura M, Teichberg VI, Uhl GR. Organization and expression of the gene encoding chick kainate binding protein, a member of the glutamate receptor family. Brain Research. Molecular Brain Research. 16: 179-86. PMID 1337927 DOI: 10.1016/0169-328X(92)90223-X  1
1992 Shimada S, Cutting G, Uhl GR. gamma-Aminobutyric acid A or C receptor? gamma-Aminobutyric acid rho 1 receptor RNA induces bicuculline-, barbiturate-, and benzodiazepine-insensitive gamma-aminobutyric acid responses in Xenopus oocytes. Molecular Pharmacology. 41: 683-7. PMID 1314944  0.6
1991 Uhl GR, O'Hara B, Shimada S, Zaczek R, DiGiorgianni J, Nishimori T. Dopamine transporter: expression in Xenopus oocytes. Brain Research. Molecular Brain Research. 9: 23-9. PMID 1850075 DOI: 10.1016/0169-328X(91)90126-I  1
1991 Cutting GR, Lu L, O'Hara BF, Kasch LM, Montrose-Rafizadeh C, Donovan DM, Shimada S, Antonarakis SE, Guggino WB, Uhl GR. Cloning of the gamma-aminobutyric acid (GABA) rho 1 cDNA: a GABA receptor subunit highly expressed in the retina. Proceedings of the National Academy of Sciences of the United States of America. 88: 2673-7. PMID 1849271  1
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