William Pu - Publications

Affiliations: 
Cardiology Harvard - Boston Children's Hospital 

85 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Guo C, Jardin BD, Lin J, Ambroise RL, Wang Z, Yang L, Mazumdar N, Lu F, Ma Q, Cao Y, Liu C, Liu X, Lan F, Zhao M, Xiao H, ... ... Pu WT, et al. In vivo proximity proteomics uncovers palmdelphin (PALMD) as a Z-line-associated mitigator of isoproterenol-induced cardiac injury. Biorxiv : the Preprint Server For Biology. PMID 38106146 DOI: 10.1101/2023.12.06.570334  0.413
2023 Sweat ME, Cao Y, Zhang X, Burnicka-Turek O, Perez-Cervantes C, Akerberg BN, Ma Q, Wakimoto H, Gorham JM, Song MK, Trembley MA, Wang P, Lu F, Gianeselli M, Prondzynski M, ... ... Pu WT, et al. maintains atrial identity by regulating an atrial enhancer network. Biorxiv : the Preprint Server For Biology. PMID 37131696 DOI: 10.1101/2023.04.21.537535  0.457
2023 Zhou P, VanDusen NJ, Zhang Y, Cao Y, Sethi I, Hu R, Zhang S, Wang G, Ye L, Mazumdar N, Chen J, Zhang X, Guo Y, Li B, Ma Q, ... ... Pu WT, et al. Dynamic changes in P300 enhancers and enhancer-promoter contacts control mouse cardiomyocyte maturation. Developmental Cell. PMID 37071996 DOI: 10.1016/j.devcel.2023.03.020  0.757
2023 Cao Y, Zhang X, Akerberg BN, Yuan H, Sakamoto T, Xiao F, VanDusen NJ, Zhou P, Sweat ME, Wang Y, Prondzynski M, Chen J, Zhang Y, Wang P, Kelly DP, ... Pu WT, et al. In Vivo Dissection of Chamber-Selective Enhancers Reveals Estrogen-Related Receptor as a Regulator of Ventricular Cardiomyocyte Identity. Circulation. PMID 36705030 DOI: 10.1161/CIRCULATIONAHA.122.061955  0.752
2022 Akerberg AA, Trembley M, Butty V, Schwertner A, Zhao L, Beerens M, Liu X, Mahamdeh M, Yuan S, Boyer L, MacRae C, Nguyen C, Pu WT, Burns CE, Burns CG. RBPMS2 Is a Myocardial-Enriched Splicing Regulator Required for Cardiac Function. Circulation Research. PMID 36367103 DOI: 10.1161/CIRCRESAHA.122.321728  0.494
2022 Yue P, Zhang Y, Liu L, Zhou K, Xia S, Peng M, Yan H, Tang X, Chen Z, Zhang D, Guo J, Pu WT, Guo Y, Hua Y, Li Y. Yap1 modulates cardiomyocyte hypertrophy via impaired mitochondrial biogenesis in response to chronic mechanical stress overload. Theranostics. 12: 7009-7031. PMID 36276651 DOI: 10.7150/thno.74563  0.447
2022 Zhou P, Zhang Y, Sethi I, Ye L, Trembley MA, Cao Y, Akerberg BN, Xiao F, Zhang X, Li K, Jardin BD, Mazumdar N, Ma Q, He A, Zhou B, ... Pu WT, et al. GATA4 Regulates Developing Endocardium Through Interaction With ETS1. Circulation Research. PMID 36263775 DOI: 10.1161/CIRCRESAHA.120.318102  0.467
2022 Huang M, Akerberg AA, Zhang X, Yoon H, Joshi S, Hallinan C, Nguyen C, Pu WT, Haigis MC, Burns CG, Burns CE. Intrinsic myocardial defects underlie an Rbfox-deficient zebrafish model of hypoplastic left heart syndrome. Nature Communications. 13: 5877. PMID 36198703 DOI: 10.1038/s41467-022-32982-x  0.326
2022 Sheldon C, Farley A, Ma Q, Pu WT, Lin Z. Depletion of VGLL4 Causes Perinatal Lethality without Affecting Myocardial Development. Cells. 11. PMID 36139407 DOI: 10.3390/cells11182832  0.384
2022 Hylind RJ, Pereira AC, Quiat D, Chandler SF, Roston TM, Pu WT, Bezzerides VJ, Seidman JG, Seidman CE, Abrams DJ. Population Prevalence of Premature Truncating Variants in Plakophilin-2 and Association With Arrhythmogenic Right Ventricular Cardiomyopathy: a UK Biobank Analysis. Circulation. Genomic and Precision Medicine. 101161CIRCGEN1210035. PMID 35536239 DOI: 10.1161/CIRCGEN.121.003507  0.658
2022 Robbe ZL, Shi W, Wasson LK, Scialdone AP, Wilczewski CM, Sheng X, Hepperla AJ, Akerberg BN, Pu WT, Cristea IM, Davis IJ, Conlon FL. CHD4 is recruited by GATA4 and NKX2-5 to repress noncardiac gene programs in the developing heart. Genes & Development. 36: 468-482. PMID 35450884 DOI: 10.1101/gad.349154.121  0.42
2022 Yan Y, Long T, Su Q, Wang Y, Chen K, Yang T, Zhao G, Ma Q, Hu X, Liu C, Liao X, Min W, Li S, Zhang D, Yang Y, ... Pu WT, et al. Cardiac ISL1-Interacting Protein, a Cardioprotective Factor, Inhibits the Transition From Cardiac Hypertrophy to Heart Failure. Frontiers in Cardiovascular Medicine. 9: 857049. PMID 35369338 DOI: 10.3389/fcvm.2022.857049  0.389
2022 Zheng Y, VanDusen NJ, Butler CE, Ma Q, King JS, Pu WT. Efficient In Vivo Homology-Directed Repair Within Cardiomyocytes. Circulation. 145: 787-789. PMID 35254919 DOI: 10.1161/CIRCULATIONAHA.120.052383  0.699
2021 VanDusen NJ, Lee JY, Gu W, Butler CE, Sethi I, Zheng Y, King JS, Zhou P, Suo S, Guo Y, Ma Q, Yuan GC, Pu WT. Author Correction: Massively parallel in vivo CRISPR screening identifies RNF20/40 as epigenetic regulators of cardiomyocyte maturation. Nature Communications. 12: 5105. PMID 34413306 DOI: 10.1038/s41467-021-25373-1  0.718
2021 He X, Liu J, Gu F, Chen J, Lu YW, Ding J, Guo H, Nie M, Kataoka M, Lin Z, Hu X, Chen H, Liao X, Dong Y, Min W, ... ... Pu WT, et al. Cardiac CIP protein regulates dystrophic cardiomyopathy. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 34400329 DOI: 10.1016/j.ymthe.2021.08.022  0.328
2021 VanDusen NJ, Lee JY, Gu W, Butler CE, Sethi I, Zheng Y, King JS, Zhou P, Suo S, Guo Y, Ma Q, Yuan GC, Pu WW. Massively parallel in vivo CRISPR screening identifies RNF20/40 as epigenetic regulators of cardiomyocyte maturation. Nature Communications. 12: 4442. PMID 34290256 DOI: 10.1038/s41467-021-24743-z  0.751
2021 Gao Y, Sun Y, Ercan-Sencicek AG, King JS, Akerberg BN, Ma Q, Kontaridis MI, Pu WT, Lin Z. YAP/TEAD1 Complex Is a Default Repressor of Cardiac Toll-Like Receptor Genes. International Journal of Molecular Sciences. 22. PMID 34206257 DOI: 10.3390/ijms22136649  0.348
2021 Liu X, Wang S, Guo X, Li Y, Ogurlu R, Lu F, Prondzynski M, de la Serna Buzon S, Ma Q, Zhang D, Wang G, Cotton J, Guo Y, Xiao L, Milan DJ, ... ... Pu WT, et al. Increased ROS-Mediated CaMKII Activation Contributes to Calcium Handling Abnormalities and Impaired Contraction in Barth Syndrome. Circulation. PMID 33793303 DOI: 10.1161/CIRCULATIONAHA.120.048698  0.682
2021 Yu H, Zhang F, Yan P, Zhang S, Lou Y, Geng Z, Li Z, Zhang Y, Xu Y, Lu Y, Chen C, Wang D, Zhu W, Hu X, Wang J, ... ... Pu WT, et al. LARP7 Protects Against Heart Failure by Enhancing Mitochondrial Biogenesis. Circulation. PMID 33663221 DOI: 10.1161/CIRCULATIONAHA.120.050812  0.362
2021 Liu J, Wen T, Dong K, He X, Zhou H, Shen J, Fu Z, Hu G, Ma W, Li J, Wang W, Wang L, Akerberg BN, Xu J, Osman I, ... ... Pu WT, et al. TEAD1 protects against necroptosis in postmitotic cardiomyocytes through regulation of nuclear DNA-encoded mitochondrial genes. Cell Death and Differentiation. PMID 33469230 DOI: 10.1038/s41418-020-00732-5  0.309
2021 Guo Y, Cao Y, Jardin BD, Sethi I, Ma Q, Moghadaszadeh B, Troiano EC, Mazumdar N, Trembley MA, Small EM, Yuan GC, Beggs AH, Pu WT. Sarcomeres regulate murine cardiomyocyte maturation through MRTF-SRF signaling. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33361330 DOI: 10.1073/pnas.2008861118  0.361
2020 Kathiriya IS, Rao KS, Iacono G, Devine WP, Blair AP, Hota SK, Lai MH, Garay BI, Thomas R, Gong HZ, Wasson LK, Goyal P, Sukonnik T, Hu KM, Akgun GA, ... ... Pu WT, et al. Modeling Human TBX5 Haploinsufficiency Predicts Regulatory Networks for Congenital Heart Disease. Developmental Cell. PMID 33321106 DOI: 10.1016/j.devcel.2020.11.020  0.371
2020 Bezzerides VJ, Pu WT. Two sides of the same coin: new insights into mechanisms of ventricular fibrillation. Cardiovascular Research. PMID 33155033 DOI: 10.1093/cvr/cvaa246  0.636
2020 Guo H, Lu YW, Lin Z, Huang ZP, Liu J, Wang Y, Seok HY, Hu X, Ma Q, Li K, Kyselovic J, Wang Q, Lin JL, Lin JJ, Cowan DB, ... ... Pu WT, et al. Intercalated disc protein Xinβ is required for Hippo-YAP signaling in the heart. Nature Communications. 11: 4666. PMID 32938943 DOI: 10.1038/S41467-020-18379-8  0.384
2020 Konstantinidis K, Bezzerides VJ, Lai L, Isbell HM, Wei AC, Wu Y, Viswanathan MC, Blum ID, Granger JM, Heims-Waldron D, Zhang D, Luczak ED, Murphy KR, Lu F, Gratz DH, ... ... Pu WT, et al. MICAL1 constrains cardiac stress responses and protects against disease by oxidizing CaMKII. The Journal of Clinical Investigation. PMID 32749237 DOI: 10.1172/Jci133181  0.675
2020 Bezzerides VJ, Prondzynski M, Carrier L, Pu WT. Gene Therapy for Inherited Arrhythmias. Cardiovascular Research. PMID 32321160 DOI: 10.1093/cvr/cvaa107  0.664
2020 Guo Y, Pu WT. Cardiomyocyte Maturation: New Phase in Development. Circulation Research. 126: 1086-1106. PMID 32271675 DOI: 10.1161/CIRCRESAHA.119.315862  0.368
2020 Wang S, Li Y, Xu Y, Ma Q, Lin Z, Schlame M, Bezzerides VJ, Strathdee D, Pu WT. AAV Gene Therapy Prevents and Reverses Heart Failure in A Murine Knockout Model of Barth Syndrome. Circulation Research. PMID 32146862 DOI: 10.1161/CIRCRESAHA.119.315956  0.712
2020 Akerberg BN, Pu WT. Genetic and Epigenetic Control of Heart Development. Cold Spring Harbor Perspectives in Biology. 12. PMID 31818853 DOI: 10.1101/cshperspect.a036756  0.394
2019 Akerberg BN, Gu F, VanDusen NJ, Zhang X, Dong R, Li K, Zhang B, Zhou B, Sethi I, Ma Q, Wasson L, Wen T, Liu J, Dong K, Conlon FL, ... ... Pu WT, et al. A reference map of murine cardiac transcription factor chromatin occupancy identifies dynamic and conserved enhancers. Nature Communications. 10: 4907. PMID 31659164 DOI: 10.1038/S41467-019-12812-3  0.76
2019 Park SJ, Zhang D, Qi Y, Li Y, Lee KY, Bezzerides VJ, Yang P, Xia S, Kim SL, Liu X, Lu F, Pasqualini FS, Campbell PH, Geva J, Roberts AE, ... ... Pu WT, et al. Insights into the Pathogenesis of Catecholaminergic Polymorphic Ventricular Tachycardia from Engineered Human Heart Tissue. Circulation. PMID 31311300 DOI: 10.1161/Circulationaha.119.039711  0.667
2019 Bezzerides VJ, Caballero A, Wang S, Ai Y, Hylind RJ, Lu F, Heims-Waldron DA, Chambers KD, Zhang D, Abrams DJ, Pu WT. Gene Therapy for Catecholaminergic Polymorphic Ventricular Tachycardia by Inhibition of Ca/Calmodulin-Dependent Kinase II. Circulation. PMID 31155924 DOI: 10.1161/CIRCULATIONAHA.118.038514  0.681
2018 Guo Y, Jardin BD, Zhou P, Sethi I, Akerberg BN, Toepfer CN, Ai Y, Li Y, Ma Q, Guatimosim S, Hu Y, Varuzhanyan G, VanDusen NJ, Zhang D, Chan DC, ... ... Pu WT, et al. Hierarchical and stage-specific regulation of murine cardiomyocyte maturation by serum response factor. Nature Communications. 9: 3837. PMID 30242271 DOI: 10.1038/S41467-018-06347-2  0.743
2017 Zhang D, Li Y, Heims-Waldron DA, Bezzerides VJ, Guatimosim S, Guo Y, Gu F, Zhou P, Lin Z, Ma Q, Liu J, Wang DZ, Pu WT. Mitochondrial Cardiomyopathy Caused by Elevated Reactive Oxygen Species and Impaired Cardiomyocyte Proliferation. Circulation Research. PMID 29021295 DOI: 10.1161/Circresaha.117.311349  0.66
2017 VanDusen NJ, Guo Y, Gu W, Pu WT. CASAAV: A CRISPR-Based Platform for Rapid Dissection of Gene Function In Vivo. Current Protocols in Molecular Biology. 120: 31.11.1-31.11.14. PMID 28967995 DOI: 10.1002/cpmb.46  0.729
2017 Ai S, Yu X, Li Y, Peng Y, Li C, Yue Y, Tao G, Li CY, Pu WT, He A. Divergent Requirements for EZH1 in Heart Development Versus Regeneration. Circulation Research. PMID 28512107 DOI: 10.1161/CIRCRESAHA.117.311212  0.382
2017 Ai S, Peng Y, Li C, Gu F, Yu X, Yue Y, Ma Q, Chen J, Lin Z, Zhou P, Xie H, Prendiville TW, Zheng W, Liu Y, Orkin SH, ... ... Pu WT, et al. EED orchestration of heart maturation through interaction with HDACs is H3K27me3-independent. Elife. 6. PMID 28394251 DOI: 10.7554/Elife.24570  0.353
2017 Guo Y, VanDusen NJ, Zhang L, Gu W, Sethi I, Guatimosim S, Ma Q, Jardin BD, Ai Y, Zhang D, Chen B, Guo A, Yuan GC, Song LS, Pu WT. Analysis of Cardiac Myocyte Maturation Using CASAAV, A Platform for Rapid Dissection of Cardiac Myocyte Gene Function In Vivo. Circulation Research. PMID 28356340 DOI: 10.1161/Circresaha.116.310283  0.761
2017 Galdos FX, Guo Y, Paige SL, VanDusen NJ, Wu SM, Pu WT. Cardiac Regeneration: Lessons From Development. Circulation Research. 120: 941-959. PMID 28302741 DOI: 10.1161/Circresaha.116.309040  0.743
2016 Ding J, Lin ZQ, Jiang JM, Seidman CE, Seidman JG, Pu WT, Wang DZ. Preparation of rAAV9 to Overexpress or Knockdown Genes in Mouse Hearts. Journal of Visualized Experiments : Jove. PMID 28060283 DOI: 10.3791/54787  0.38
2016 Bezzerides VJ, Zhang D, Pu WT. Modeling Inherited Arrhythmia Disorders Using Induced Pluripotent Stem Cell-Derived Cardiomyocytes. Circulation Journal : Official Journal of the Japanese Circulation Society. PMID 27916777 DOI: 10.1253/circj.CJ-16-1113  0.634
2016 DeLaughter DM, Bick AG, Wakimoto H, McKean D, Gorham JM, Kathiriya IS, Hinson JT, Homsy J, Gray J, Pu W, Bruneau BG, Seidman JG, Seidman CE. Single-Cell Resolution of Temporal Gene Expression during Heart Development. Developmental Cell. PMID 27840107 DOI: 10.1016/J.Devcel.2016.10.001  0.355
2016 Lin Z, Guo H, Cao Y, Zohrabian S, Zhou P, Ma Q, VanDusen N, Guo Y, Zhang J, Stevens SM, Liang F, Quan Q, van Gorp PR, Li A, Dos Remedios C, ... ... Pu WT, et al. Acetylation of VGLL4 Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth. Developmental Cell. PMID 27720608 DOI: 10.1016/J.Devcel.2016.09.005  0.765
2016 Stevens SM, Gise AV, VanDusen N, Zhou B, Pu WT. Epicardium is required for cardiac seeding by yolk sac macrophages, precursors of resident macrophages of the adult heart. Developmental Biology. PMID 26988120 DOI: 10.1016/j.ydbio.2016.03.014  0.741
2016 Yu W, Huang X, Tian X, Zhang H, He L, Wang Y, Nie Y, Hu S, Lin Z, Zhou B, Pu W, Lui KO, Zhou B. GATA4 regulates Fgf16 to promote heart repair after injury. Development (Cambridge, England). PMID 26893347 DOI: 10.1242/dev.130971  0.391
2015 Huang ZP, Kataoka M, Chen J, Wu G, Ding J, Nie M, Lin Z, Liu J, Hu X, Ma L, Zhou B, Wakimoto H, Zeng C, Kyselovic J, Deng ZL, ... ... Pu WT, et al. Cardiomyocyte-enriched protein CIP protects against pathophysiological stresses and regulates cardiac homeostasis. The Journal of Clinical Investigation. PMID 26436652 DOI: 10.1172/Jci82423  0.408
2015 Vicente-Steijn R, Scherptong RW, Kruithof BP, Duim SN, Goumans MJ, Wisse LJ, Zhou B, Pu WT, Poelmann RE, Schalij MJ, Tallquist MD, Gittenberger-de Groot AC, Jongbloed MR. Regional differences in WT-1 and Tcf21 expression during ventricular development: implications for myocardial compaction. Plos One. 10: e0136025. PMID 26390289 DOI: 10.1371/journal.pone.0136025  0.306
2015 Ding J, Chen J, Wang Y, Kataoka M, Ma L, Zhou P, Hu X, Lin Z, Nie M, Deng ZL, Pu WT, Wang DZ. Trbp regulates heart function through microRNA-mediated Sox6 repression. Nature Genetics. 47: 776-83. PMID 26029872 DOI: 10.1038/Ng.3324  0.368
2015 Prendiville TW, Guo H, Lin Z, Zhou P, Stevens SM, He A, VanDusen N, Chen J, Zhong L, Wang DZ, Gao G, Pu WT. Novel Roles of GATA4/6 in the Postnatal Heart Identified through Temporally Controlled, Cardiomyocyte-Specific Gene Inactivation by Adeno-Associated Virus Delivery of Cre Recombinase. Plos One. 10: e0128105. PMID 26023924 DOI: 10.1371/Journal.Pone.0128105  0.779
2014 Harvey RP, Graham RM, Pu WT. Introduction to the special issue on heart regeneration and rejuvenation. Stem Cell Research. 13: 521-2. PMID 25459518 DOI: 10.1016/j.scr.2014.10.003  0.325
2014 Prendiville T, Jay PY, Pu WT. Insights into the genetic structure of congenital heart disease from human and murine studies on monogenic disorders. Cold Spring Harbor Perspectives in Medicine. 4. PMID 25274754 DOI: 10.1101/Cshperspect.A013946  0.352
2014 He A, Gu F, Hu Y, Ma Q, Ye LY, Akiyama JA, Visel A, Pennacchio LA, Pu WT. Dynamic GATA4 enhancers shape the chromatin landscape central to heart development and disease. Nature Communications. 5: 4907. PMID 25249388 DOI: 10.1038/ncomms5907  0.355
2014 Lin Z, Pu WT. Strategies for cardiac regeneration and repair. Science Translational Medicine. 6: 239rv1. PMID 24898748 DOI: 10.1126/scitranslmed.3006681  0.324
2014 Lin Z, von Gise A, Zhou P, Gu F, Ma Q, Jiang J, Yau AL, Buck JN, Gouin KA, van Gorp PR, Zhou B, Chen J, Seidman JG, Wang DZ, Pu WT. Cardiac-specific YAP activation improves cardiac function and survival in an experimental murine MI model. Circulation Research. 115: 354-63. PMID 24833660 DOI: 10.1161/Circresaha.115.303632  0.391
2014 Zhang H, von Gise A, Liu Q, Hu T, Tian X, He L, Pu W, Huang X, He L, Cai CL, Camargo FD, Pu WT, Zhou B. Yap1 is required for endothelial to mesenchymal transition of the atrioventricular cushion. The Journal of Biological Chemistry. 289: 18681-92. PMID 24831012 DOI: 10.1074/jbc.M114.554584  0.333
2014 Wang G, McCain ML, Yang L, He A, Pasqualini FS, Agarwal A, Yuan H, Jiang D, Zhang D, Zangi L, Geva J, Roberts AE, Ma Q, Ding J, Chen J, ... ... Pu WT, et al. Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies. Nature Medicine. 20: 616-23. PMID 24813252 DOI: 10.1038/Nm.3545  0.302
2013 Christoffels VM, Pu WT. Developing insights into cardiac regeneration Development (Cambridge). 140: 3933-3937. PMID 24046314 DOI: 10.1242/dev.096867  0.323
2013 Sah R, Mesirca P, Mason X, Gibson W, Bates-Withers C, Van den Boogert M, Chaudhuri D, Pu WT, Mangoni ME, Clapham DE. Timing of myocardial trpm7 deletion during cardiogenesis variably disrupts adult ventricular function, conduction, and repolarization. Circulation. 128: 101-14. PMID 23734001 DOI: 10.1161/Circulationaha.112.000768  0.599
2012 Smart N, Bollini S, Dubé KN, Vieira JM, Zhou B, Riegler J, Price AN, Lythgoe MF, Davidson S, Yellon D, Pu WT, Riley PR. Myocardial regeneration: expanding the repertoire of thymosin β4 in the ischemic heart. Annals of the New York Academy of Sciences. 1269: 92-101. PMID 23045976 DOI: 10.1111/j.1749-6632.2012.06708.x  0.31
2012 von Gise A, Pu WT. Endocardial and epicardial epithelial to mesenchymal transitions in heart development and disease. Circulation Research. 110: 1628-45. PMID 22679138 DOI: 10.1161/CIRCRESAHA.111.259960  0.332
2012 Misra C, Sachan N, McNally CR, Koenig SN, Nichols HA, Guggilam A, Lucchesi PA, Pu WT, Srivastava D, Garg V. Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo. Plos Genetics. 8: e1002690. PMID 22589735 DOI: 10.1371/Journal.Pgen.1002690  0.337
2012 Zhou P, He A, Pu WT. Regulation of GATA4 Transcriptional Activity in Cardiovascular Development and Disease Current Topics in Developmental Biology. 100: 143-169. PMID 22449843 DOI: 10.1016/B978-0-12-387786-4.00005-1  0.323
2012 Ounzain S, Kobayashi S, Peterson RE, He A, Motterle A, Samani NJ, Menick DR, Pu WT, Liang Q, Chong NW. Cardiac expression of ms1/STARS, a novel gene involved in cardiac development and disease, is regulated by GATA4. Molecular and Cellular Biology. 32: 1830-43. PMID 22431517 DOI: 10.1128/Mcb.06374-11  0.338
2012 Huang ZP, Young Seok H, Zhou B, Chen J, Chen JF, Tao Y, Pu WT, Wang DZ. CIP, a cardiac Isl1-interacting protein, represses cardiomyocyte hypertrophy. Circulation Research. 110: 818-30. PMID 22343712 DOI: 10.1161/Circresaha.111.259663  0.369
2012 von Gise A, Lin Z, Schlegelmilch K, Honor LB, Pan GM, Buck JN, Ma Q, Ishiwata T, Zhou B, Camargo FD, Pu WT. YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy. Proceedings of the National Academy of Sciences of the United States of America. 109: 2394-9. PMID 22308401 DOI: 10.1073/pnas.1116136109  0.364
2012 He A, Shen X, Ma Q, Cao J, von Gise A, Zhou P, Wang G, Marquez VE, Orkin SH, Pu WT. PRC2 directly methylates GATA4 and represses its transcriptional activity. Genes & Development. 26: 37-42. PMID 22215809 DOI: 10.1101/Gad.173930.111  0.304
2012 He A, Ma Q, Cao J, von Gise A, Zhou P, Xie H, Zhang B, Hsing M, Christodoulou DC, Cahan P, Daley GQ, Kong SW, Orkin SH, Seidman CE, Seidman JG, ... Pu WT, et al. Polycomb repressive complex 2 regulates normal development of the mouse heart. Circulation Research. 110: 406-15. PMID 22158708 DOI: 10.1161/Circresaha.111.252205  0.301
2011 van Berlo JH, Elrod JW, Aronow BJ, Pu WT, Molkentin JD. Serine 105 phosphorylation of transcription factor GATA4 is necessary for stress-induced cardiac hypertrophy in vivo. Proceedings of the National Academy of Sciences of the United States of America. 108: 12331-6. PMID 21746915 DOI: 10.1073/Pnas.1104499108  0.38
2011 Zhou B, Honor LB, He H, Ma Q, Oh JH, Butterfield C, Lin RZ, Melero-Martin JM, Dolmatova E, Duffy HS, Gise Av, Zhou P, Hu YW, Wang G, Zhang B, ... ... Pu WT, et al. Adult mouse epicardium modulates myocardial injury by secreting paracrine factors. The Journal of Clinical Investigation. 121: 1894-904. PMID 21505261 DOI: 10.1172/JCI45529  0.323
2011 He A, Kong SW, Ma Q, Pu WT. Co-occupancy by multiple cardiac transcription factors identifies transcriptional enhancers active in heart. Proceedings of the National Academy of Sciences of the United States of America. 108: 5632-7. PMID 21415370 DOI: 10.1073/pnas.1016959108  0.406
2009 Pu WT. Identification of a cardiac disease modifier gene using forward genetics in the mouse Plos Genetics. 5. PMID 19763163 DOI: 10.1371/journal.pgen.1000643  0.302
2009 Zhou B, Ma Q, Kong SW, Hu Y, Campbell PH, McGowan FX, Ackerman KG, Wu B, Zhou B, Tevosian SG, Pu WT. Fog2 is critical for cardiac function and maintenance of coronary vasculature in the adult mouse heart. The Journal of Clinical Investigation. 119: 1462-76. PMID 19411759 DOI: 10.1172/JCI38723  0.362
2008 Ma Q, Zhou B, Pu WT. Reassessment of Isl1 and Nkx2-5 cardiac fate maps using a Gata4-based reporter of Cre activity. Developmental Biology. 323: 98-104. PMID 18775691 DOI: 10.1016/j.ydbio.2008.08.013  0.315
2008 Zhou B, von Gise A, Ma Q, Rivera-Feliciano J, Pu WT. Nkx2-5- and Isl1-expressing cardiac progenitors contribute to proepicardium. Biochemical and Biophysical Research Communications. 375: 450-3. PMID 18722343 DOI: 10.1016/J.Bbrc.2008.08.044  0.361
2008 Rojas A, Kong SW, Agarwal P, Gilliss B, Pu WT, Black BL. GATA4 is a direct transcriptional activator of cyclin D2 and Cdk4 and is required for cardiomyocyte proliferation in anterior heart field-derived myocardium. Molecular and Cellular Biology. 28: 5420-31. PMID 18591257 DOI: 10.1128/Mcb.00717-08  0.396
2008 Zhou B, Ma Q, Rajagopal S, Wu SM, Domian I, Rivera-Feliciano J, Jiang D, von Gise A, Ikeda S, Chien KR, Pu WT. Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart. Nature. 454: 109-13. PMID 18568026 DOI: 10.1038/Nature07060  0.364
2007 Ikeda S, Kong SW, Lu J, Bisping E, Zhang H, Allen PD, Golub TR, Pieske B, Pu WT. Altered microRNA expression in human heart disease. Physiological Genomics. 31: 367-73. PMID 17712037 DOI: 10.1152/Physiolgenomics.00144.2007  0.315
2007 Jay PY, Bielinska M, Erlich JM, Mannisto S, Pu WT, Heikinheimo M, Wilson DB. Impaired mesenchymal cell function in Gata4 mutant mice leads to diaphragmatic hernias and primary lung defects. Developmental Biology. 301: 602-14. PMID 17069789 DOI: 10.1016/J.Ydbio.2006.09.050  0.303
2006 Bisping E, Ikeda S, Kong SW, Tarnavski O, Bodyak N, McMullen JR, Rajagopal S, Son JK, Ma Q, Springer Z, Kang PM, Izumo S, Pu WT. Gata4 is required for maintenance of postnatal cardiac function and protection from pressure overload-induced heart failure. Proceedings of the National Academy of Sciences of the United States of America. 103: 14471-6. PMID 16983087 DOI: 10.1073/pnas.0602543103  0.3
2006 Rivera-Feliciano J, Lee KH, Kong SW, Rajagopal S, Ma Q, Springer Z, Izumo S, Tabin CJ, Pu WT. Development of heart valves requires Gata4 expression in endothelial-derived cells. Development (Cambridge, England). 133: 3607-18. PMID 16914500 DOI: 10.1242/Dev.02519  0.335
2006 Kobayashi S, Lackey T, Huang Y, Bisping E, Pu WT, Boxer LM, Liang Q. Transcription factor gata4 regulates cardiac BCL2 gene expression in vitro and in vivo. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 800-2. PMID 16469847 DOI: 10.1096/Fj.05-5426Fje  0.381
2004 Pu WT, Ishiwata T, Juraszek AL, Ma Q, Izumo S. GATA4 is a dosage-sensitive regulator of cardiac morphogenesis. Developmental Biology. 275: 235-44. PMID 15464586 DOI: 10.1016/j.ydbio.2004.08.008  0.4
2003 Ishiwata T, Nakazawa M, Pu WT, Tevosian SG, Izumo S. Developmental changes in ventricular diastolic function correlate with changes in ventricular myoarchitecture in normal mouse embryos. Circulation Research. 93: 857-65. PMID 14551244 DOI: 10.1161/01.RES.0000100389.57520.1A  0.305
2003 Pu WT, Ma Q, Izumo S. NFAT transcription factors are critical survival factors that inhibit cardiomyocyte apoptosis during phenylephrine stimulation in vitro. Circulation Research. 92: 725-31. PMID 12663489 DOI: 10.1161/01.RES.0000069211.82346.46  0.304
2002 Wickman K, Pu WT, Clapham DE. Structural characterization of the mouse Girk genes. Gene. 284: 241-50. PMID 11891065 DOI: 10.1016/S0378-1119(01)00884-8  0.631
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