Kevin Wickman - Publications

Affiliations: 
1991-1995 Pharmacology Mayo Clinc, Rochester, Rochester, MN, United States 
 1995-1997 Mayo Clinic, Phoenix, AZ 
 1997-1999 Cardiovascular Biology Harvard Medical School - Boston Children's Hospital 
 1999- Pharmacology University of Minnesota, Twin Cities, Minneapolis, MN 
Area:
Pharmacology, Neuroscience Biology

106 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Oh Y, Yoo ES, Ju SH, Kim E, Lee S, Kim S, Wickman K, Sohn JW. GIRK2 potassium channels expressed by the AgRP neurons decrease adiposity and body weight in mice. Plos Biology. 21: e3002252. PMID 37594983 DOI: 10.1371/journal.pbio.3002252  0.339
2023 Fernandez de Velasco EM, Tipps ME, Haider B, Souders A, Aguado C, Rose TR, Vo BN, DeBaker MC, Luján R, Wickman K. Ethanol-induced suppression of GIRK-dependent signaling in the basal amygdala. Biological Psychiatry. PMID 37068702 DOI: 10.1016/j.biopsych.2023.04.006  0.715
2023 DeBaker MC, Mitten EH, Rose TR, de Velasco EMF, Gao R, Lee AM, Wickman K. RGS6 negatively regulates inhibitory G protein signaling in VTA dopamine neurons and positively regulates binge-like alcohol consumption in mice. British Journal of Pharmacology. PMID 36929333 DOI: 10.1111/bph.16071  0.809
2022 Rose TR, Marron Fernandez de Velasco E, Mitten EH, Wickman K. GIRK channel activity in prelimbic pyramidal neurons regulates the extinction of cocaine conditioned place preference in male mice. Addiction Biology. 28: e13256. PMID 36577727 DOI: 10.1111/adb.13256  0.83
2022 Lin K, Chang YC, Marron Fernandez de Velasco E, Wickman K, Myers CL, Bielinsky AK. Scalable CRISPR-Cas9 chemical genetic screens in non-transformed human cells. Star Protocols. 3: 101675. PMID 36107744 DOI: 10.1016/j.xpro.2022.101675  0.649
2022 Rienecker KDA, Poston RG, Segales JS, Finholm IW, Sono MH, Munteanu SJ, Ghaninejad-Esfahani M, Rejepova A, Tejeda-Garibay S, Wickman K, Marron Fernandez de Velasco E, Thayer SA, Saha RN. Mild membrane depolarization in neurons induces immediate early gene transcription and acutely subdues responses to successive stimulus. The Journal of Biological Chemistry. 102278. PMID 35863435 DOI: 10.1016/j.jbc.2022.102278  0.726
2022 Luo H, Marron Fernandez de Velasco E, Wickman K. Neuronal G protein-gated K channels. American Journal of Physiology. Cell Physiology. PMID 35704701 DOI: 10.1152/ajpcell.00102.2022  0.81
2022 Taylor EL, Weaver SR, Lorang IM, Arnold KM, Bradley EW, Marron Fernandez de Velasco E, Wickman K, Westendorf JJ. GIRK3 deletion facilitates kappa opioid signaling in chondrocytes, delays vascularization and promotes bone lengthening in mice. Bone. 159: 116391. PMID 35314385 DOI: 10.1016/j.bone.2022.116391  0.713
2021 Anderson A, Vo BN, Marron Fernandez de Velasco E, Hopkins CR, Weaver CD, Wickman K. . Molecular Pharmacology. PMID 34503975 DOI: 10.1124/molpharm.121.000311  0.842
2021 Vo BN, Marron Fernandez de Velasco E, Rose TR, Oberle H, Luo H, Hopkins CR, Wickman K. Bidirectional influence of limbic GIRK channel activation on innate avoidance behavior. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34039657 DOI: 10.1523/JNEUROSCI.2787-20.2021  0.764
2021 DeBaker MC, Marron Fernandez de Velasco E, McCall NM, Lee AM, Wickman K. Differential impact of inhibitory G protein signaling pathways in ventral tegmental area dopamine neurons on behavioral sensitivity to cocaine and morphine. Eneuro. PMID 33707203 DOI: 10.1523/ENEURO.0081-21.2021  0.822
2021 Rose TR, Marron Fernandez de Velasco E, Vo BN, Tipps ME, Wickman K. Impact of acute and persistent excitation of prelimbic pyramidal neurons on motor activity and trace fear learning. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33402420 DOI: 10.1523/JNEUROSCI.2606-20.2020  0.829
2020 Rose TR, Wickman K. Mechanisms and Regulation of Neuronal GABA Receptor-Dependent Signaling. Current Topics in Behavioral Neurosciences. PMID 32808092 DOI: 10.1007/7854_2020_129  0.465
2020 Moen JK, DeBaker MC, Myjak JE, Wickman K, Lee AM. Bidirectional sex-dependent regulation of α6 and β3 nicotinic acetylcholine receptors by protein kinase Cε. Addiction Biology. e12954. PMID 32776643 DOI: 10.1111/Adb.12954  0.31
2020 Bidaud I, Chong ACY, Carcouet A, Waard S, Charpentier F, Ronjat M, Waard M, Isbrandt D, Wickman K, Vincent A, Mangoni ME, Mesirca P. Inhibition of G protein-gated K channels by tertiapin-Q rescues sinus node dysfunction and atrioventricular conduction in mouse models of primary bradycardia. Scientific Reports. 10: 9835. PMID 32555258 DOI: 10.1038/S41598-020-66673-8  0.363
2020 Anderson A, Masuho I, Marron Fernandez de Velasco E, Nakano A, Birnbaumer L, Martemyanov KA, Wickman K. GPCR-dependent biasing of GIRK channel signaling dynamics by RGS6 in mouse sinoatrial nodal cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 32513692 DOI: 10.1073/Pnas.2001270117  0.813
2020 Chao OY, de Velasco EMF, Pathak SS, Maitra S, Zhang H, Duvick L, Wickman K, Orr HT, Hirai H, Yang YM. Targeting inhibitory cerebellar circuitry to alleviate behavioral deficits in a mouse model for studying idiopathic autism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32179875 DOI: 10.1038/S41386-020-0656-5  0.384
2020 Anderson A, Masuho I, Marron E, Martemyanov K, Wickman K. Influence of RGS6 on Inhibitory G Protein Signaling in Mouse Sinoatrial Nodal Cells The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.05399  0.669
2019 Vo BN, Abney KK, Anderson A, Marron Fernandez de Velasco E, Benneyworth MA, Daniels JS, Morrison RD, Hopkins CR, Weaver CD, Wickman K. VU0810464, a non-urea GIRK channel activator, exhibits enhanced selectivity for neuronal GIRK channels and reduces stress-induced hyperthermia in mice. British Journal of Pharmacology. PMID 30924523 DOI: 10.1111/Bph.14671  0.847
2019 McCall NM, Fernandez de Velasco EM, Wickman K. GIRK channel activity in dopamine neurons of the ventral tegmental area bi-directionally regulates behavioral sensitivity to cocaine. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30837265 DOI: 10.1523/Jneurosci.3101-18.2019  0.827
2018 Abney KK, Bubser M, Du Y, Kozek KA, Bridges TM, Lindsley CW, Daniels JS, Morrison RD, Wickman K, Hopkins CR, Jones CK, Weaver CD. Analgesic effects of the GIRK Activator, VU0466551, alone and in combination with morphine in acute and persistent pain models. Acs Chemical Neuroscience. PMID 30474955 DOI: 10.1021/Acschemneuro.8B00370  0.481
2018 Tipps M, Marron Fernandez de Velasco E, Schaeffer A, Wickman K. Inhibition of Pyramidal Neurons in the Basal Amygdala Promotes Fear Learning. Eneuro. 5. PMID 30406197 DOI: 10.1523/ENEURO.0272-18.2018  0.798
2018 Lee SW, Anderson A, Guzman PA, Nakano A, Tolkacheva EG, Wickman K. Atrial GIRK Channels Mediate the Effects of Vagus Nerve Stimulation on Heart Rate Dynamics and Arrhythmogenesis. Frontiers in Physiology. 9: 943. PMID 30072916 DOI: 10.3389/Fphys.2018.00943  0.733
2018 Kulkarni K, Xie X, Marron Fernandez de Velasco E, Anderson A, Martemyanov KA, Wickman K, Tolkacheva EG. Correction: The influences of the M2R-GIRK4-RGS6 dependent parasympathetic pathway on electrophysiological properties of the mouse heart. Plos One. 13: e0200553. PMID 29979785 DOI: 10.1371/Journal.Pone.0200553  0.766
2018 Kulkarni K, Xie X, Fernandez de Velasco EM, Anderson A, Martemyanov KA, Wickman K, Tolkacheva EG. The influences of the M2R-GIRK4-RGS6 dependent parasympathetic pathway on electrophysiological properties of the mouse heart. Plos One. 13: e0193798. PMID 29668674 DOI: 10.1371/Journal.Pone.0193798  0.689
2018 Anderson A, Kulkarni K, Marron Fernandez de Velasco E, Carlblom N, Xia Z, Nakano A, Martemyanov KA, Tolkacheva EG, Wickman K. Expression and relevance of the G protein-gated K+ channel in the mouse ventricle. Scientific Reports. 8: 1192. PMID 29352184 DOI: 10.1038/S41598-018-19719-X  0.838
2017 Luján R, Aguado C, Ciruela F, Cózar J, Kleindienst D, de la Ossa L, Bettler B, Wickman K, Watanabe M, Shigemoto R, Fukazawa Y. Differential association of GABAB receptors with their effector ion channels in Purkinje cells. Brain Structure & Function. PMID 29177691 DOI: 10.1007/S00429-017-1568-Y  0.347
2017 Wieting JM, Vadukoot AK, Sharma SH, Abney KK, Bridges TM, Daniels JS, Morrison RD, Wickman K, Weaver CD, Hopkins CR. Discovery and characterization of 1H-pyrazol-5-yl-2-phenylacetamides as novel, non-urea containing GIRK1/2 potassium channel activators. Acs Chemical Neuroscience. PMID 28697302 DOI: 10.1021/Acschemneuro.7B00217  0.44
2017 Marron Fernandez de Velasco E, Zhang L, N Vo B, Tipps M, Farris S, Xia Z, Anderson A, Carlblom N, Weaver CD, Dudek SM, Wickman K. GIRK2 splice variants and neuronal G protein-gated K(+) channels: implications for channel function and behavior. Scientific Reports. 7: 1639. PMID 28487514 DOI: 10.1038/S41598-017-01820-2  0.83
2017 Marron Fernandez de Velasco E, Carlblom N, Xia Z, Wickman K. Suppression of inhibitory G protein signaling in forebrain pyramidal neurons triggers plasticity of glutamatergic neurotransmission in the nucleus accumbens core. Neuropharmacology. PMID 28131769 DOI: 10.1016/J.Neuropharm.2017.01.021  0.783
2016 McCall NM, Kotecki L, Dominguez-Lopez S, de Velasco EM, Carlblom N, Sharpe AL, Beckstead MJ, Wickman K. Selective Ablation of GIRK Channels in Dopamine Neurons Alters Behavioral Effects of Cocaine in Mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27468917 DOI: 10.1038/Npp.2016.138  0.818
2016 Munoz MB, Padgett CL, Rifkin R, Terunuma M, Wickman K, Contet C, Moss SJ, Slesinger PA. A Role for the GIRK3 Subunit in Methamphetamine-Induced Attenuation of GABAB Receptor-Activated GIRK Currents in VTA Dopamine Neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 3106-14. PMID 26985023 DOI: 10.1523/Jneurosci.1327-15.2016  0.47
2016 Mesirca P, Bidaud I, Briec F, Evain S, Torrente AG, Le Quang K, Leoni AL, Baudot M, Marger L, Chung You Chong A, Nargeot J, Striessnig J, Wickman K, Charpentier F, Mangoni ME. G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block. Proceedings of the National Academy of Sciences of the United States of America. PMID 26831068 DOI: 10.1073/Pnas.1517181113  0.412
2015 Montandon G, Ren J, Victoria NC, Liu H, Wickman K, Greer JJ, Horner RL. G-protein-gated Inwardly Rectifying Potassium Channels Modulate Respiratory Depression by Opioids. Anesthesiology. PMID 26675532 DOI: 10.1097/ALN.0000000000000984  0.399
2015 Victoria NC, Marron Fernandez de Velasco E, Ostrovskaya O, Metzger S, Xia Z, Kotecki L, Benneyworth MA, Zink AN, Martemyanov KA, Wickman K. G Protein-Gated K+ Channel Ablation in Forebrain Pyramidal Neurons Selectively Impairs Fear Learning. Biological Psychiatry. PMID 26612516 DOI: 10.1016/J.Biopsych.2015.10.004  0.801
2015 Marron Fernandez de Velasco E, McCall N, Wickman K. GIRK Channel Plasticity and Implications for Drug Addiction. International Review of Neurobiology. 123: 201-38. PMID 26422986 DOI: 10.1016/Bs.Irn.2015.05.011  0.836
2015 Kotecki L, Hearing M, McCall NM, Marron Fernandez de Velasco E, Pravetoni M, Arora D, Victoria NC, Munoz MB, Xia Z, Slesinger PA, Weaver CD, Wickman K. GIRK Channels Modulate Opioid-Induced Motor Activity in a Cell Type- and Subunit-Dependent Manner. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 7131-42. PMID 25948263 DOI: 10.1523/Jneurosci.5051-14.2015  0.824
2015 Marron Fernandez de Velasco E, Hearing M, Xia Z, Victoria NC, Luján R, Wickman K. Sex differences in GABABR-GIRK signaling in layer 5/6 pyramidal neurons of the mouse prelimbic cortex. Neuropharmacology. 95: 353-60. PMID 25843643 DOI: 10.1016/j.neuropharm.2015.03.029  0.813
2015 Kotecki L, Hearing M, McCall NM, de Velasco EMF, Pravetoni M, Arora D, Victoria NC, Munoz MB, Xia Z, Slesinger PA, Weaver CD, Wickman K. GIRK channels modulate opioid-induced motor activity in a cell type- and subunit-dependent manner Journal of Neuroscience. 35: 7131-7142. DOI: 10.1523/JNEUROSCI.5051-14.2015  0.788
2015 de Velasco EMF, McCall N, Wickman K. GIRK Channel Plasticity and Implications for Drug Addiction International Review of Neurobiology. 123: 201-238. DOI: 10.1016/bs.irn.2015.05.011  0.775
2014 Mesirca P, Alig J, Torrente AG, Müller JC, Marger L, Rollin A, Marquilly C, Vincent A, Dubel S, Bidaud I, Fernandez A, Seniuk A, Engeland B, Singh J, Miquerol L, ... ... Wickman K, et al. Cardiac arrhythmia induced by genetic silencing of 'funny' (f) channels is rescued by GIRK4 inactivation. Nature Communications. 5: 4664. PMID 25144323 DOI: 10.1038/ncomms5664  0.34
2014 Wydeven N, Marron Fernandez de Velasco E, Du Y, Benneyworth MA, Hearing MC, Fischer RA, Thomas MJ, Weaver CD, Wickman K. Mechanisms underlying the activation of G-protein-gated inwardly rectifying K+ (GIRK) channels by the novel anxiolytic drug, ML297. Proceedings of the National Academy of Sciences of the United States of America. 111: 10755-60. PMID 25002517 DOI: 10.1073/Pnas.1405190111  0.822
2014 Ostrovskaya O, Xie K, Masuho I, Fajardo-Serrano A, Lujan R, Wickman K, Martemyanov KA. RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling. Elife. 3: e02053. PMID 24755289 DOI: 10.7554/Elife.02053  0.375
2014 Krogh KA, Wydeven N, Wickman K, Thayer SA. HIV-1 protein Tat produces biphasic changes in NMDA-evoked increases in intracellular Ca2+ concentration via activation of Src kinase and nitric oxide signaling pathways. Journal of Neurochemistry. 130: 642-56. PMID 24666322 DOI: 10.1111/Jnc.12724  0.766
2014 Wydeven N, Posokhova E, Xia Z, Martemyanov KA, Wickman K. RGS6, but not RGS4, is the dominant regulator of G protein signaling (RGS) modulator of the parasympathetic regulation of mouse heart rate. The Journal of Biological Chemistry. 289: 2440-9. PMID 24318880 DOI: 10.1074/Jbc.M113.520742  0.807
2014 Luján R, Marron Fernandez de Velasco E, Aguado C, Wickman K. New insights into the therapeutic potential of Girk channels. Trends in Neurosciences. 37: 20-9. PMID 24268819 DOI: 10.1016/j.tins.2013.10.006  0.785
2014 Liang B, Nissen JD, Laursen M, Wang X, Skibsbye L, Hearing MC, Andersen MN, Rasmussen HB, Wickman K, Grunnet M, Olesen SP, Jespersen T. G-protein-coupled inward rectifier potassium current contributes to ventricular repolarization. Cardiovascular Research. 101: 175-84. PMID 24148898 DOI: 10.1093/Cvr/Cvt240  0.748
2014 Mesirca P, Lequang K, Torrente AG, Marger L, Leoni AL, Briec F, Evain S, Nargeot J, Striessnig J, Wickman K, Charpentier F, Mangoni ME. 0257: Genetic inactivation of Kir3.4 (GIRK4) channels improves heart rate and abolishes atrial tachyarrhythmias in a mouse model of sick-sinus syndrome Archives of Cardiovascular Diseases Supplements. 6: 33. DOI: 10.1016/S1878-6480(14)71352-7  0.368
2014 Mesirca P, Alig J, Marger L, Torrente AG, Rollin A, Marquilly C, Vincent A, Dubel S, Fernandez A, Seniouk A, Engeland B, Singh J, Miquerol L, Ehmke H, Eschenhagen T, ... ... Wickman K, et al. 0252: Bradycardia and arrhythmia caused by cardiac-specific suppression of the “funny” (If) current are rescued by Girk Archives of Cardiovascular Diseases Supplements. 6: 33. DOI: 10.1016/S1878-6480(14)71351-5  0.405
2013 Posokhova E, Ng D, Opel A, Masuho I, Tinker A, Biesecker LG, Wickman K, Martemyanov KA. Essential role of the m2R-RGS6-IKACh pathway in controlling intrinsic heart rate variability. Plos One. 8: e76973. PMID 24204714 DOI: 10.1371/Journal.Pone.0076973  0.309
2013 Hearing M, Kotecki L, Marron Fernandez de Velasco E, Fajardo-Serrano A, Chung HJ, Luján R, Wickman K. Repeated cocaine weakens GABA(B)-Girk signaling in layer 5/6 pyramidal neurons in the prelimbic cortex. Neuron. 80: 159-70. PMID 24094109 DOI: 10.1016/J.Neuron.2013.07.019  0.794
2013 Mesirca P, Marger L, Toyoda F, Rizzetto R, Audoubert M, Dubel S, Torrente AG, Difrancesco ML, Muller JC, Leoni AL, Couette B, Nargeot J, Clapham DE, Wickman K, Mangoni ME. The G-protein-gated K+ channel, IKACh, is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation. The Journal of General Physiology. 142: 113-26. PMID 23858001 DOI: 10.1085/Jgp.201310996  0.572
2013 Fajardo-Serrano A, Wydeven N, Young D, Watanabe M, Shigemoto R, Martemyanov KA, Wickman K, Luján R. Association of Rgs7/Gβ5 complexes with Girk channels and GABAB receptors in hippocampal CA1 pyramidal neurons. Hippocampus. 23: 1231-45. PMID 23804514 DOI: 10.1002/Hipo.22161  0.822
2013 Booker SA, Gross A, Althof D, Shigemoto R, Bettler B, Frotscher M, Hearing M, Wickman K, Watanabe M, Kulik Á, Vida I. Differential GABAB-receptor-mediated effects in perisomatic- and dendrite-targeting parvalbumin interneurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 7961-74. PMID 23637187 DOI: 10.1523/Jneurosci.1186-12.2013  0.729
2012 Wydeven N, Young D, Mirkovic K, Wickman K. Structural elements in the Girk1 subunit that potentiate G protein-gated potassium channel activity. Proceedings of the National Academy of Sciences of the United States of America. 109: 21492-7. PMID 23236146 DOI: 10.1073/Pnas.1212019110  0.832
2012 Mirkovic K, Palmersheim J, Lesage F, Wickman K. Behavioral characterization of mice lacking Trek channels. Frontiers in Behavioral Neuroscience. 6: 60. PMID 22973213 DOI: 10.3389/Fnbeh.2012.00060  0.782
2012 Hearing MC, Zink AN, Wickman K. Cocaine-induced adaptations in metabotropic inhibitory signaling in the mesocorticolimbic system. Reviews in the Neurosciences. 23: 325-51. PMID 22944653 DOI: 10.1515/revneuro-2012-0045  0.742
2011 Fernández-Alacid L, Watanabe M, Molnár E, Wickman K, Luján R. Developmental regulation of G protein-gated inwardly-rectifying K+ (GIRK/Kir3) channel subunits in the brain. The European Journal of Neuroscience. 34: 1724-36. PMID 22098295 DOI: 10.1111/J.1460-9568.2011.07886.X  0.509
2011 Arora D, Hearing M, Haluk DM, Mirkovic K, Fajardo-Serrano A, Wessendorf MW, Watanabe M, Luján R, Wickman K. Acute cocaine exposure weakens GABA(B) receptor-dependent G-protein-gated inwardly rectifying K+ signaling in dopamine neurons of the ventral tegmental area. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 12251-7. PMID 21865468 DOI: 10.1523/Jneurosci.0494-11.2011  0.816
2011 Mirkovic K, Wickman K. Identification and characterization of alternative splice variants of the mouse Trek2/Kcnk10 gene. Neuroscience. 194: 11-8. PMID 21821104 DOI: 10.1016/J.Neuroscience.2011.07.064  0.777
2011 Wickman K, Hedin KE, Perez‐Terzic CM, Krapivinsky GB, Stehno‐Bittel L, Velimirovic B, Clapham DE. Mechanisms of Transmembrane Signaling Comprehensive Physiology. 689-742. DOI: 10.1002/Cphy.Cp140118  0.519
2010 Posokhova E, Wydeven N, Allen KL, Wickman K, Martemyanov KA. RGS6/Gβ5 complex accelerates IKACh gating kinetics in atrial myocytes and modulates parasympathetic regulation of heart rate. Circulation Research. 107: 1350-4. PMID 20884879 DOI: 10.1161/Circresaha.110.224212  0.799
2010 Arora D, Haluk DM, Kourrich S, Pravetoni M, Fernández-Alacid L, Nicolau JC, Luján R, Wickman K. Altered neurotransmission in the mesolimbic reward system of Girk mice. Journal of Neurochemistry. 114: 1487-97. PMID 20557431 DOI: 10.1111/J.1471-4159.2010.06864.X  0.708
2010 Xie K, Allen KL, Kourrich S, Colón-Saez J, Thomas MJ, Wickman K, Martemyanov KA. Gbeta5 recruits R7 RGS proteins to GIRK channels to regulate the timing of neuronal inhibitory signaling. Nature Neuroscience. 13: 661-3. PMID 20453851 DOI: 10.1038/Nn.2549  0.391
2010 Anderson GR, Cao Y, Davidson S, Truong HV, Pravetoni M, Thomas MJ, Wickman K, Giesler GJ, Martemyanov KA. R7BP complexes with RGS9-2 and RGS7 in the striatum differentially control motor learning and locomotor responses to cocaine. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 1040-50. PMID 20043004 DOI: 10.1038/Npp.2009.212  0.692
2009 Fernández-Alacid L, Aguado C, Ciruela F, Martín R, Colón J, Cabañero MJ, Gassmann M, Watanabe M, Shigemoto R, Wickman K, Bettler B, Sánchez-Prieto J, Luján R. Subcellular compartment-specific molecular diversity of pre- and post-synaptic GABA-activated GIRK channels in Purkinje cells. Journal of Neurochemistry. 110: 1363-76. PMID 19558451 DOI: 10.1111/J.1471-4159.2009.06229.X  0.453
2008 Torrecilla M, Quillinan N, Williams JT, Wickman K. Pre- and postsynaptic regulation of locus coeruleus neurons after chronic morphine treatment: a study of GIRK-knockout mice. The European Journal of Neuroscience. 28: 618-24. PMID 18702733 DOI: 10.1111/J.1460-9568.2008.06348.X  0.412
2008 Perry CA, Pravetoni M, Teske JA, Aguado C, Erickson DJ, Medrano JF, Luján R, Kotz CM, Wickman K. Predisposition to late-onset obesity in GIRK4 knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 8148-53. PMID 18523006 DOI: 10.1073/Pnas.0803261105  0.818
2008 Cruz HG, Berton F, Sollini M, Blanchet C, Pravetoni M, Wickman K, Lüscher C. Absence and rescue of morphine withdrawal in GIRK/Kir3 knock-out mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4069-77. PMID 18400906 DOI: 10.1523/Jneurosci.0267-08.2008  0.68
2008 Smith SB, Marker CL, Perry C, Liao G, Sotocinal SG, Austin JS, Melmed K, Clark JD, Peltz G, Wickman K, Mogil JS. Quantitative trait locus and computational mapping identifies Kcnj9 (GIRK3) as a candidate gene affecting analgesia from multiple drug classes. Pharmacogenetics and Genomics. 18: 231-41. PMID 18300945 DOI: 10.1097/Fpc.0B013E3282F55Ab2  0.783
2008 Pravetoni M, Wickman K. Behavioral characterization of mice lacking GIRK/Kir3 channel subunits. Genes, Brain, and Behavior. 7: 523-31. PMID 18194467 DOI: 10.1111/J.1601-183X.2008.00388.X  0.716
2008 Aguado C, Colón J, Ciruela F, Schlaudraff F, Cabañero MJ, Perry C, Watanabe M, Liss B, Wickman K, Luján R. Cell type-specific subunit composition of G protein-gated potassium channels in the cerebellum. Journal of Neurochemistry. 105: 497-511. PMID 18088366 DOI: 10.1111/J.1471-4159.2007.05153.X  0.785
2008 Aguado C, Colón J, Ciruela F, Schlaudraff F, Cabañero MC, Perry C, Watanabe M, Liss B, Wickman K, Luján R. Cell type-specific subunit composition of G-protein-gated potassium channels in the cerebellum (Journal of Neurochemistry (2008) 105, (497-511)) Journal of Neurochemistry. 105: 2053-2054. DOI: 10.1111/J.1471-4159.2008.05394.X  0.764
2007 Anderson GR, Lujan R, Semenov A, Pravetoni M, Posokhova EN, Song JH, Uversky V, Chen CK, Wickman K, Martemyanov KA. Expression and localization of RGS9-2/G 5/R7BP complex in vivo is set by dynamic control of its constitutive degradation by cellular cysteine proteases. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 14117-27. PMID 18094251 DOI: 10.1523/Jneurosci.3884-07.2007  0.665
2007 Labouèbe G, Lomazzi M, Cruz HG, Creton C, Luján R, Li M, Yanagawa Y, Obata K, Watanabe M, Wickman K, Boyer SB, Slesinger PA, Lüscher C. RGS2 modulates coupling between GABAB receptors and GIRK channels in dopamine neurons of the ventral tegmental area. Nature Neuroscience. 10: 1559-68. PMID 17965710 DOI: 10.1038/Nn2006  0.498
2006 Marker CL, Luján R, Colón J, Wickman K. Distinct populations of spinal cord lamina II interneurons expressing G-protein-gated potassium channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12251-9. PMID 17122050 DOI: 10.1523/Jneurosci.3693-06.2006  0.809
2006 Kulik A, Vida I, Fukazawa Y, Guetg N, Kasugai Y, Marker CL, Rigato F, Bettler B, Wickman K, Frotscher M, Shigemoto R. Compartment-dependent colocalization of Kir3.2-containing K+ channels and GABAB receptors in hippocampal pyramidal cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4289-97. PMID 16624949 DOI: 10.1523/Jneurosci.4178-05.2006  0.828
2005 Koyrakh L, Luján R, Colón J, Karschin C, Kurachi Y, Karschin A, Wickman K. Molecular and cellular diversity of neuronal G-protein-gated potassium channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 11468-78. PMID 16339040 DOI: 10.1523/Jneurosci.3484-05.2005  0.558
2005 Marker CL, Luján R, Loh HH, Wickman K. Spinal G-protein-gated potassium channels contribute in a dose-dependent manner to the analgesic effect of mu- and delta- but not kappa-opioids. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3551-9. PMID 15814785 DOI: 10.1523/Jneurosci.4899-04.2005  0.803
2005 Koyrakh L, Roman MI, Brinkmann V, Wickman K. The heart rate decrease caused by acute FTY720 administration is mediated by the G protein-gated potassium channel I. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 5: 529-36. PMID 15707407 DOI: 10.1111/j.1600-6143.2005.00754.x  0.381
2004 Marker CL, Stoffel M, Wickman K. Spinal G-protein-gated K+ channels formed by GIRK1 and GIRK2 subunits modulate thermal nociception and contribute to morphine analgesia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2806-12. PMID 15028774 DOI: 10.1523/Jneurosci.5251-03.2004  0.832
2003 Grosse G, Eulitz D, Thiele T, Pahner I, Schröter S, Takamori S, Grosse J, Wickman K, Tapp R, Veh RW, Ottersen OP, Ahnert-Hilger G. Axonal sorting of Kir3.3 defines a GABA-containing neuron in the CA3 region of rodent hippocampus. Molecular and Cellular Neurosciences. 24: 709-24. PMID 14664820 DOI: 10.1016/S1044-7431(03)00234-3  0.398
2003 Morgan AD, Carroll ME, Loth AK, Stoffel M, Wickman K. Decreased cocaine self-administration in Kir3 potassium channel subunit knockout mice. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 28: 932-8. PMID 12637950 DOI: 10.1038/Sj.Npp.1300100  0.455
2002 Marker CL, Cintora SC, Roman MI, Stoffel M, Wickman K. Hyperalgesia and blunted morphine analgesia in G protein-gated potassium channel subunit knockout mice. Neuroreport. 13: 2509-13. PMID 12499858 DOI: 10.1097/00001756-200212200-00026  0.814
2002 Bettahi I, Marker CL, Roman MI, Wickman K. Contribution of the Kir3.1 subunit to the muscarinic-gated atrial potassium channel IKACh. The Journal of Biological Chemistry. 277: 48282-8. PMID 12374786 DOI: 10.1074/Jbc.M209599200  0.832
2002 Torrecilla M, Marker CL, Cintora SC, Stoffel M, Williams JT, Wickman K. G-protein-gated potassium channels containing Kir3.2 and Kir3.3 subunits mediate the acute inhibitory effects of opioids on locus ceruleus neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 4328-34. PMID 12040038 DOI: 10.1523/Jneurosci.22-11-04328.2002  0.842
2002 Wickman K, Pu WT, Clapham DE. Structural characterization of the mouse Girk genes. Gene. 284: 241-50. PMID 11891065 DOI: 10.1016/S0378-1119(01)00884-8  0.717
2001 Kovoor P, Wickman K, Maguire CT, Pu W, Gehrmann J, Berul CI, Clapham DE. Evaluation of the role of I(KACh) in atrial fibrillation using a mouse knockout model. Journal of the American College of Cardiology. 37: 2136-43. PMID 11419900 DOI: 10.1016/S0735-1097(01)01304-3  0.52
2000 Jelacic TM, Kennedy ME, Wickman K, Clapham DE. Functional and biochemical evidence for G-protein-gated inwardly rectifying K+ (GIRK) channels composed of GIRK2 and GIRK3. The Journal of Biological Chemistry. 275: 36211-6. PMID 10956667 DOI: 10.1074/Jbc.M007087200  0.649
2000 Wickman K, Karschin C, Karschin A, Picciotto MR, Clapham DE. Brain localization and behavioral impact of the G-protein-gated K+ channel subunit GIRK4. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 5608-15. PMID 10908597 DOI: 10.1523/Jneurosci.20-15-05608.2000  0.61
2000 Pu WT, Wickman K, Clapham DE. ICln is essential for cellular and early embryonic viability. The Journal of Biological Chemistry. 275: 12363-6. PMID 10777517 DOI: 10.1074/jbc.275.17.12363  0.419
1999 Wickman K, Krapivinsky G, Corey S, Kennedy M, Nemec J, Medina I, Clapham DE. Structure, G protein activation, and functional relevance of the cardiac G protein-gated K+ channel, IKACh. Annals of the New York Academy of Sciences. 868: 386-98. PMID 10414308 DOI: 10.1111/j.1749-6632.1999.tb11300.x  0.569
1999 Kennedy ME, Nemec J, Corey S, Wickman K, Clapham DE. GIRK4 confers appropriate processing and cell surface localization to G-protein-gated potassium channels. The Journal of Biological Chemistry. 274: 2571-82. PMID 9891030 DOI: 10.1074/Jbc.274.4.2571  0.585
1999 Nemec J, Wickman K, Clapham DE. Gbetagamma binding increases the open time of IKACh: kinetic evidence for multiple Gbetagamma binding sites. Biophysical Journal. 76: 246-52. PMID 9876138 DOI: 10.1016/S0006-3495(99)77193-6  0.578
1998 Krapivinsky G, Pu W, Wickman K, Krapivinsky L, Clapham DE. pICln binds to a mammalian homolog of a yeast protein involved in regulation of cell morphology. The Journal of Biological Chemistry. 273: 10811-4. PMID 9556550 DOI: 10.1074/Jbc.273.18.10811  0.512
1998 Wickman K, Nemec J, Gendler SJ, Clapham DE. Abnormal heart rate regulation in GIRK4 knockout mice. Neuron. 20: 103-14. PMID 9459446 DOI: 10.1016/S0896-6273(00)80438-9  0.546
1997 Wickman K, Seldin MF, James MR, Gendler SJ, Clapham DE. Partial structure, chromosome localization, and expression of the mouse Icln gene. Genomics. 40: 402-8. PMID 9073507 DOI: 10.1006/geno.1996.4600  0.496
1997 Wickman K, Seldin MF, Gendler SJ, Clapham DE. Partial structure, chromosome localization, and expression of the mouse Girk4 gene. Genomics. 40: 395-401. PMID 9073506 DOI: 10.1006/Geno.1997.4599  0.574
1995 Krapivinsky G, Gordon EA, Wickman K, Velimirović B, Krapivinsky L, Clapham DE. The G-protein-gated atrial K+ channel IKACh is a heteromultimer of two inwardly rectifying K(+)-channel proteins. Nature. 374: 135-41. PMID 7877685 DOI: 10.1038/374135A0  0.632
1995 Wickman KD, Clapham DE. G-protein regulation of ion channels. Current Opinion in Neurobiology. 5: 278-85. PMID 7580149 DOI: 10.1016/0959-4388(95)80039-5  0.573
1995 Krapivinsky G, Krapivinsky L, Velimirovic B, Wickman K, Navarro B, Clapham DE. The cardiac inward rectifier K+ channel subunit, CIR, does not comprise the ATP-sensitive K+ channel, IKATP. The Journal of Biological Chemistry. 270: 28777-9. PMID 7499400 DOI: 10.1074/Jbc.270.48.28777  0.557
1995 Krapivinsky G, Krapivinsky L, Wickman K, Clapham DE. G beta gamma binds directly to the G protein-gated K+ channel, IKACh. The Journal of Biological Chemistry. 270: 29059-62. PMID 7493925 DOI: 10.1074/Jbc.270.49.29059  0.563
1995 Wickman K, Clapham DE. Ion channel regulation by G proteins. Physiological Reviews. 75: 865-85. PMID 7480165 DOI: 10.1152/Physrev.1995.75.4.865  0.562
1994 Ackerman MJ, Wickman KD, Clapham DE. Hypotonicity activates a native chloride current in Xenopus oocytes. The Journal of General Physiology. 103: 153-79. PMID 8189203 DOI: 10.1085/Jgp.103.2.153  0.549
1994 Wickman KD, Iñiguez-Lluhl JA, Davenport PA, Taussig R, Krapivinsky GB, Linder ME, Gilman AG, Clapham DE. Recombinant G-protein beta gamma-subunits activate the muscarinic-gated atrial potassium channel. Nature. 368: 255-7. PMID 8145826 DOI: 10.1038/368255A0  0.492
1992 Paulmichl M, Li Y, Wickman K, Ackerman M, Peralta E, Clapham D. New mammalian chloride channel identified by expression cloning. Nature. 356: 238-41. PMID 1313151 DOI: 10.1038/356238A0  0.583
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