Hisashi Umemori - Publications

Harvard Medical School, Boston, MA, United States 
Synapse formation

75 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Yasuda M, Nagappan-Chettiar S, Umemori H. intraocular AAV injection for early gene expression in the developing rodent retina. Star Protocols. 2: 100742. PMID 34430915 DOI: 10.1016/j.xpro.2021.100742  1
2021 Hoshina N, Johnson-Venkatesh EM, Hoshina M, Umemori H. Female-specific synaptic dysfunction and cognitive impairment in a mouse model of disorder. Science (New York, N.Y.). 372. PMID 33859005 DOI: 10.1126/science.aaz3893  1
2021 Yasuda M, Nagappan-Chettiar S, Johnson-Venkatesh EM, Umemori H. An activity-dependent determinant of synapse elimination in the mammalian brain. Neuron. PMID 33770504 DOI: 10.1016/j.neuron.2021.03.006  1
2020 Li T, Chiou B, Gilman CK, Luo R, Koshi T, Yu D, Oak HC, Giera S, Johnson-Venkatesh E, Muthukumar AK, Stevens B, Umemori H, Piao X. A splicing isoform of GPR56 mediates microglial synaptic refinement via phosphatidylserine binding. The Embo Journal. e104136. PMID 32452062 DOI: 10.15252/Embj.2019104136  0.04
2020 Luo L, Ambrozkiewicz MC, Benseler F, Chen C, Dumontier E, Falkner S, Furlanis E, Gomez AM, Hoshina N, Huang WH, Hutchison MA, Itoh-Maruoka Y, Lavery LA, Li W, Maruo T, ... ... Umemori H, et al. Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors. Neuron. PMID 32027825 DOI: 10.1016/J.Neuron.2020.01.008  1
2019 Terauchi A, Durlacher E, Pitino J, Umemori H. Neuronal fibroblast growth factor 22 signaling during development, but not in adults, is involved in anhedonia. Neuroreport. PMID 31895747 DOI: 10.1097/WNR.0000000000001399  1
2018 Lehrman EK, Wilton DK, Litvina EY, Welsh CA, Chang ST, Frouin A, Walker AJ, Heller MD, Umemori H, Chen C, Stevens B. CD47 Protects Synapses from Excess Microglia-Mediated Pruning during Development. Neuron. 100: 120-134.e6. PMID 30308165 DOI: 10.1016/J.Neuron.2018.09.017  0.01
2018 Nagappan-Chettiar S, Johnson-Venkatesh EM, Umemori H. Tyrosine phosphorylation of the transmembrane protein SIRPα: Sensing synaptic activity and regulating ectodomain cleavage for synapse maturation. The Journal of Biological Chemistry. PMID 29914984 DOI: 10.1074/jbc.RA117.001488  1
2017 Terauchi A, Gavin E, Wilson J, Umemori H. Selective Inactivation of Fibroblast Growth Factor 22 (FGF22) in CA3 Pyramidal Neurons Impairs Local Synaptogenesis and Affective Behavior Without Affecting Dentate Neurogenesis. Frontiers in Synaptic Neuroscience. 9: 17. PMID 29311892 DOI: 10.3389/fnsyn.2017.00017  1
2016 Mathew RS, Tatarakis A, Rudenko A, Johnson-Venkatesh EM, Yang YJ, Murphy EA, Todd TP, Schepers SP, Siuti N, Martorell AJ, Falls WA, Hammack SE, Walsh CA, Tsai LH, Umemori H, et al. Inhibition of memory by a microRNA negative feedback loop that downregulates SNARE-mediated vesicle transport. Elife. 5. PMID 28001126 DOI: 10.7554/Elife.22467  1
2016 Chettiar SN, Johnson-Venkatesh EM, Umemori H. Activity-dependent proteolytic cleavage of cell adhesion molecules regulates excitatory synaptic development and function. Neuroscience Research. PMID 27965136 DOI: 10.1016/j.neures.2016.12.003  1
2016 Hu HT, Umemori H, Hsueh YP. Postsynaptic SDC2 induces transsynaptic signaling via FGF22 for bidirectional synaptic formation. Scientific Reports. 6: 33592. PMID 27627962 DOI: 10.1038/srep33592  1
2016 Dabrowski A, Umemori H. Buttressing a balanced brain: Target-derived FGF signaling regulates excitatory/inhibitory tone and adult neurogenesis within the maturating hippocampal network. Neurogenesis (Austin, Tex.). 3: e1168504. PMID 27605441 DOI: 10.1080/23262133.2016.1168504  1
2016 Terauchi A, Johnson-Venkatesh EM, Bullock B, Lehtinen M, Umemori H. Retrograde fibroblast growth factor 22 (FGF22) signaling regulates insulin-like growth factor 2 (IGF2) expression for activity-dependent synapse stabilization in the mammalian brain. Elife. 5. PMID 27083047 DOI: 10.7554/Elife.12151  1
2016 Williams AJ, Yee P, Smith MC, Murphy GG, Umemori H. Deletion of Fibroblast Growth Factor 22 (FGF22) causes a depression-like phenotype in adult mice. Behavioural Brain Research. PMID 27036645 DOI: 10.1016/j.bbr.2016.03.047  1
2016 Mathew RS, Tatarakis A, Rudenko A, Johnson-Venkatesh EM, Yang YJ, Murphy EA, Todd TP, Schepers ST, Siuti N, Martorell AJ, Falls WA, Hammack SE, Walsh CA, Tsai L, Umemori H, et al. Author response: A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory Elife. DOI: 10.7554/Elife.22467.030  1
2015 Johnson-Venkatesh EM, Khan MN, Murphy GG, Sutton MA, Umemori H. Excitability governs neural development in a hippocampal region specific manner. Development (Cambridge, England). PMID 26417041 DOI: 10.1242/dev.121202  1
2015 Dabrowski A, Terauchi A, Strong C, Umemori H. Distinct sets of FGF receptors sculpt excitatory and inhibitory synaptogenesis. Development (Cambridge, England). 142: 1818-30. PMID 25926357 DOI: 10.1242/dev.115568  1
2015 Jacobi A, Loy K, Schmalz AM, Hellsten M, Umemori H, Kerschensteiner M, Bareyre FM. FGF22 signaling regulates synapse formation during post-injury remodeling of the spinal cord. The Embo Journal. 34: 1231-43. PMID 25766255 DOI: 10.15252/Embj.201490578  1
2015 Terauchi A, Timmons KM, Kikuma K, Pechmann Y, Kneussel M, Umemori H. Selective synaptic targeting of the excitatory and inhibitory presynaptic organizers FGF22 and FGF7. Journal of Cell Science. 128: 281-92. PMID 25431136 DOI: 10.1242/jcs.158337  1
2015 Dabrowski A, Terauchi A, Strong C, Umemori H. Distinct sets of FGF receptors sculpt excitatory and inhibitory synaptogenesis Development (Cambridge). 142: 1818-1830. DOI: 10.1242/dev.115568  1
2014 Wang Q, Terauchi A, Yee CH, Umemori H, Traynor JR. 5-HT1A receptor-mediated phosphorylation of extracellular signal-regulated kinases (ERK1/2) is modulated by regulator of G protein signaling protein 19. Cellular Signalling. 26: 1846-52. PMID 24793302 DOI: 10.1016/j.cellsig.2014.04.017  1
2014 Williams AJ, Umemori H. The best-laid plans go oft awry: synaptogenic growth factor signaling in neuropsychiatric disease. Frontiers in Synaptic Neuroscience. 6: 4. PMID 24672476 DOI: 10.3389/fnsyn.2014.00004  1
2013 Toth AB, Terauchi A, Zhang LY, Johnson-Venkatesh EM, Larsen DJ, Sutton MA, Umemori H. Synapse maturation by activity-dependent ectodomain shedding of SIRPα. Nature Neuroscience. 16: 1417-25. PMID 24036914 DOI: 10.1038/nn.3516  1
2013 Lee CH, Umemori H. Suppression of epileptogenesis-associated changes in response to seizures in FGF22-deficient mice. Frontiers in Cellular Neuroscience. 7: 43. PMID 23616746 DOI: 10.3389/fncel.2013.00043  1
2012 Lee CH, Javed D, Althaus AL, Parent JM, Umemori H. Neurogenesis is enhanced and mossy fiber sprouting arises in FGF7-deficient mice during development. Molecular and Cellular Neurosciences. 51: 61-7. PMID 22889808 DOI: 10.1016/j.mcn.2012.07.010  1
2012 Singh R, Su J, Brooks J, Terauchi A, Umemori H, Fox MA. Fibroblast growth factor 22 contributes to the development of retinal nerve terminals in the dorsal lateral geniculate nucleus. Frontiers in Molecular Neuroscience. 4: 61. PMID 22363257 DOI: 10.3389/Fnmol.2011.00061  1
2012 Terauchi A, Umemori H. Specific sets of intrinsic and extrinsic factors drive excitatory and inhibitory circuit formation. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 18: 271-86. PMID 21652588 DOI: 10.1177/1073858411404228  1
2011 Yasuda M, Johnson-Venkatesh EM, Zhang H, Parent JM, Sutton MA, Umemori H. Multiple forms of activity-dependent competition refine hippocampal circuits in vivo. Neuron. 70: 1128-42. PMID 21689599 DOI: 10.1016/j.neuron.2011.04.027  1
2011 Dabrowski A, Umemori H. Orchestrating the synaptic network by tyrosine phosphorylation signalling. Journal of Biochemistry. 149: 641-53. PMID 21508038 DOI: 10.1093/jb/mvr047  1
2010 Delawary M, Tezuka T, Kiyama Y, Yokoyama K, Inoue T, Hattori S, Hashimoto R, Umemori H, Manabe T, Yamamoto T, Nakazawa T. NMDAR2B tyrosine phosphorylation regulates anxiety-like behavior and CRF expression in the amygdala. Molecular Brain. 3: 37. PMID 21118530 DOI: 10.1186/1756-6606-3-37  1
2010 Johnson-Venkatesh EM, Umemori H. Secreted factors as synaptic organizers. The European Journal of Neuroscience. 32: 181-90. PMID 20646052 DOI: 10.1111/j.1460-9568.2010.07338.x  1
2010 Terauchi A, Johnson-Venkatesh EM, Toth AB, Javed D, Sutton MA, Umemori H. Distinct FGFs promote differentiation of excitatory and inhibitory synapses. Nature. 465: 783-7. PMID 20505669 DOI: 10.1038/nature09041  1
2010 Umemori H, Miyazawa K, Baba A. Experimental study on bracing effects on SIP shear walls Aij Journal of Technology and Design. 16: 967-972. DOI: 10.3130/aijt.16.967  1
2010 Baba A, Miyazawa K, Umemori H. Experimental study on influence of multiple forces, initial deformation and loading speed to shear strength of SIP shear walls Aij Journal of Technology and Design. 16: 951-954. DOI: 10.3130/aijt.16.951  1
2009 Taniguchi S, Nakazawa T, Tanimura A, Kiyama Y, Tezuka T, Watabe AM, Katayama N, Yokoyama K, Inoue T, Izumi-Nakaseko H, Kakuta S, Sudo K, Iwakura Y, Umemori H, Inoue T, et al. Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour. The Embo Journal. 28: 3717-29. PMID 19834457 DOI: 10.1038/Emboj.2009.300  1
2009 Umemori H. Weaving the neuronal net with target-derived fibroblast growth factors. Development, Growth & Differentiation. 51: 263-70. PMID 19210540 DOI: 10.1111/j.1440-169X.2008.01079.x  1
2009 Umemori H, Tsuzuki N, Miyazawa K. A study of properties of SIP shear wall structure by static load test of three-story full-scale building Aij Journal of Technology and Design. 15: 95-98. DOI: 10.3130/aijt.15.95  1
2009 Umemori H, Baba A, Kawakami O, Miyazawa K. Experimental study on influence of overdriven of nail to shear strength of sip shear walls Aij Journal of Technology and Design. 15: 731-734. DOI: 10.3130/aijt.15.731  1
2009 Umemori H, Miyazawa K. Experimental study on effect of wall height on SIP shear walls Aij Journal of Technology and Design. 15: 417-420. DOI: 10.3130/aijt.15.417  1
2009 Yasuda M, Umemori H. Synapse formation in the mammalian central nervous system The Sticky Synapse: Cell Adhesion Molecules and Their Role in Synapse Formation and Maintenance. 85-106. DOI: 10.1007/978-0-387-92708-4_4  1
2009 Hortsch M, Umemori H. Preface The Sticky Synapse: Cell Adhesion Molecules and Their Role in Synapse Formation and Maintenance. v. DOI: 10.1007/978-0-387-92708-4  1
2008 Umemori H, Sanes JR. Signal regulatory proteins (SIRPS) are secreted presynaptic organizing molecules. The Journal of Biological Chemistry. 283: 34053-61. PMID 18819922 DOI: 10.1074/jbc.M805729200  1
2008 Nakazawa T, Kuriu T, Tezuka T, Umemori H, Okabe S, Yamamoto T. Regulation of dendritic spine morphology by an NMDA receptor-associated Rho GTPase-activating protein, p250GAP. Journal of Neurochemistry. 105: 1384-93. PMID 18331582 DOI: 10.1111/J.1471-4159.2008.05335.X  1
2008 Okiura H, Kawai N, Isoda H, Kawai M, Umemori H, Murakami T. Full-scale shaking table tests of 3-story wood-frame construction buildings 10th World Conference On Timber Engineering 2008. 4: 1850-1857.  1
2008 Umemori H, Tsuzuki N, Miyazawa K. Shaking table test and seismic property evaluation of wooden house with various types of shear walls 10th World Conference On Timber Engineering 2008. 4: 1858-1865.  1
2007 Fox MA, Sanes JR, Borza DB, Eswarakumar VP, Fässler R, Hudson BG, John SW, Ninomiya Y, Pedchenko V, Pfaff SL, Rheault MN, Sado Y, Segal Y, Werle MJ, Umemori H. Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals. Cell. 129: 179-93. PMID 17418794 DOI: 10.1016/J.Cell.2007.02.035  1
2007 Ishida A, Noda Y, Bole DG, Umemori H, Ueda T. Coupling of glycolysis to synaptic transmission: Role of synaptic vesicle-associated pyruvate kinase in neurotransmitter uptake into synaptic vesicles Journal of Cerebral Blood Flow and Metabolism. 27: BP50-02H.  1
2006 Nakazawa T, Komai S, Watabe AM, Kiyama Y, Fukaya M, Arima-Yoshida F, Horai R, Sudo K, Ebine K, Delawary M, Goto J, Umemori H, Tezuka T, Iwakura Y, Watanabe M, et al. NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity. The Embo Journal. 25: 2867-77. PMID 16710293 DOI: 10.1038/Sj.Emboj.7601156  1
2006 Fox MA, Umemori H. Seeking long-term relationship: axon and target communicate to organize synaptic differentiation. Journal of Neurochemistry. 97: 1215-31. PMID 16638017 DOI: 10.1111/J.1471-4159.2006.03834.X  1
2006 Zhang X, Ibrahimi OA, Olsen SK, Umemori H, Mohammadi M, Ornitz DM. Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. The Journal of Biological Chemistry. 281: 15694-700. PMID 16597617 DOI: 10.1074/Jbc.M601252200  1
2004 Umemori H, Linhoff MW, Ornitz DM, Sanes JR. FGF22 and its close relatives are presynaptic organizing molecules in the mammalian brain. Cell. 118: 257-70. PMID 15260994 DOI: 10.1016/J.Cell.2004.06.025  1
2003 Nakazawa T, Watabe AM, Tezuka T, Yoshida Y, Yokoyama K, Umemori H, Inoue A, Okabe S, Manabe T, Yamamoto T. p250GAP, a novel brain-enriched GTPase-activating protein for Rho family GTPases, is involved in the N-methyl-d-aspartate receptor signaling. Molecular Biology of the Cell. 14: 2921-34. PMID 12857875 DOI: 10.1091/Mbc.E02-09-0623  1
2003 Yoshida Y, von Bubnoff A, Ikematsu N, Blitz IL, Tsuzuku JK, Yoshida EH, Umemori H, Miyazono K, Yamamoto T, Cho KW. Tob proteins enhance inhibitory Smad-receptor interactions to repress BMP signaling. Mechanisms of Development. 120: 629-37. PMID 12782279 DOI: 10.1016/S0925-4773(03)00020-0  1
2003 Yoshida Y, Nakamura T, Komoda M, Satoh H, Suzuki T, Tsuzuku JK, Miyasaka T, Yoshida EH, Umemori H, Kunisaki RK, Tani K, Ishii S, Mori S, Suganuma M, Noda T, et al. Mice lacking a transcriptional corepressor Tob are predisposed to cancer. Genes & Development. 17: 1201-6. PMID 12756225 DOI: 10.1101/Gad.1088003  1
2003 Umemori H, Ogura H, Tozawa N, Mikoshiba K, Nishizumi H, Yamamoto T. Impairment of N-methyl-D-aspartate receptor-controlled motor activity in LYN-deficient mice. Neuroscience. 118: 709-13. PMID 12710978 DOI: 10.1016/S0306-4522(03)00025-3  1
2003 Kohda K, Kamiya Y, Matsuda S, Kato K, Umemori H, Yuzaki M. Heteromer formation of delta2 glutamate receptors with AMPA or kainate receptors. Brain Research. Molecular Brain Research. 110: 27-37. PMID 12573530 DOI: 10.1016/S0169-328X(02)00561-2  1
2001 Nakazawa T, Komai S, Tezuka T, Hisatsune C, Umemori H, Semba K, Mishina M, Manabe T, Yamamoto T. Characterization of Fyn-mediated tyrosine phosphorylation sites on GluR epsilon 2 (NR2B) subunit of the N-methyl-D-aspartate receptor. The Journal of Biological Chemistry. 276: 693-9. PMID 11024032 DOI: 10.1074/Jbc.M008085200  1
2000 Yoshida Y, Tanaka S, Umemori H, Minowa O, Usui M, Ikematsu N, Hosoda E, Imamura T, Kuno J, Yamashita T, Miyazono K, Noda M, Noda T, Yamamoto T. Negative regulation of BMP/Smad signaling by Tob in osteoblasts. Cell. 103: 1085-97. PMID 11163184 DOI: 10.1016/S0092-8674(00)00211-7  1
2000 Hironaka K, Umemori H, Tezuka T, Mishina M, Yamamoto T. The protein-tyrosine phosphatase PTPMEG interacts with glutamate receptor delta 2 and epsilon subunits. The Journal of Biological Chemistry. 275: 16167-73. PMID 10748123 DOI: 10.1074/Jbc.M909302199  1
1999 Hisatsune C, Umemori H, Mishina M, Yamamoto T. Phosphorylation-dependent interaction of the N-methyl-D-aspartate receptor epsilon 2 subunit with phosphatidylinositol 3-kinase. Genes to Cells : Devoted to Molecular & Cellular Mechanisms. 4: 657-66. PMID 10620012 DOI: 10.1046/J.1365-2443.1999.00287.X  1
1999 Umemori H, Hayashi T, Inoue T, Nakanishi S, Mikoshiba K, Yamamoto T. Involvement of protein tyrosine phosphatases in activation of the trimeric G protein Gq/11. Oncogene. 18: 7399-402. PMID 10602498 DOI: 10.1038/Sj.Onc.1203152  1
1999 Horikawa K, Nishizumi H, Umemori H, Aizawa S, Takatsu K, Yamamoto T. Distinctive roles of Fyn and Lyn in IgD- and IgM-mediated signaling. International Immunology. 11: 1441-9. PMID 10464165 DOI: 10.1093/Intimm/11.9.1441  1
1999 Umemori H, Kadowaki Y, Hirosawa K, Yoshida Y, Hironaka K, Okano H, Yamamoto T. Stimulation of myelin basic protein gene transcription by Fyn tyrosine kinase for myelination. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 1393-7. PMID 9952416 DOI: 10.1523/Jneurosci.19-04-01393.1999  1
1999 Tezuka T, Umemori H, Akiyama T, Nakanishi S, Yamamoto T. PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A. Proceedings of the National Academy of Sciences of the United States of America. 96: 435-40. PMID 9892651 DOI: 10.1073/Pnas.96.2.435  1
1999 Hayashi T, Umemori H, Mishina M, Yamamoto T. The AMPA receptor interacts with and signals through the protein tyrosine kinase Lyn. Nature. 397: 72-6. PMID 9892356 DOI: 10.1038/16269  1
1998 Miyatake S, Nakaseko C, Umemori H, Yamamoto T, Saito T. Src family tyrosine kinases associate with and phosphorylate CTLA-4 (CD152). Biochemical and Biophysical Research Communications. 249: 444-8. PMID 9712716 DOI: 10.1006/Bbrc.1998.9191  1
1998 Yoshida Y, Matsuda S, Ikematsu N, Kawamura-Tsuzuku J, Inazawa J, Umemori H, Yamamoto T. ANA, a novel member of Tob/BTG1 family, is expressed in the ventricular zone of the developing central nervous system. Oncogene. 16: 2687-93. PMID 9632145 DOI: 10.1038/Sj.Onc.1201805  1
1997 Hisatsune C, Umemori H, Inoue T, Michikawa T, Kohda K, Mikoshiba K, Yamamoto T. Phosphorylation-dependent regulation of N-methyl-D-aspartate receptors by calmodulin. The Journal of Biological Chemistry. 272: 20805-10. PMID 9252405 DOI: 10.1074/Jbc.272.33.20805  1
1997 Umemori H, Inoue T, Kume S, Sekiyama N, Nagao M, Itoh H, Nakanishi S, Mikoshiba K, Yamamoto T. Activation of the G protein Gq/11 through tyrosine phosphorylation of the alpha subunit. Science (New York, N.Y.). 276: 1878-81. PMID 9188537 DOI: 10.1126/Science.276.5320.1878  1
1996 Tezuka T, Umemori H, Fusaki N, Yagi T, Takata M, Kurosaki T, Yamamoto T. Physical and functional association of the cbl protooncogen product with an src-family protein tyrosine kinase, p53/56lyn, in the B cell antigen receptor-mediated signaling. The Journal of Experimental Medicine. 183: 675-80. PMID 8627181 DOI: 10.1084/Jem.183.2.675  1
1996 Fusaki N, Matsuda S, Nishizumi H, Umemori H, Yamamoto T. Physical and functional interactions of protein tyrosine kinases, p59fyn and ZAP-70, in T cell signaling. Journal of Immunology (Baltimore, Md. : 1950). 156: 1369-77. PMID 8568236  1
1994 Umemori H, Sato S, Yagi T, Aizawa S, Yamamoto T. Initial events of myelination involve Fyn tyrosine kinase signalling. Nature. 367: 572-6. PMID 7509042 DOI: 10.1038/367572a0  1
1993 Yamanashi Y, Okada M, Semba T, Yamori T, Umemori H, Tsunasawa S, Toyoshima K, Kitamura D, Watanabe T, Yamamoto T. Identification of HS1 protein as a major substrate of protein-tyrosine kinase(s) upon B-cell antigen receptor-mediated signaling. Proceedings of the National Academy of Sciences of the United States of America. 90: 3631-5. PMID 7682714 DOI: 10.1073/Pnas.90.8.3631  1
1992 Umemori H, Wanaka A, Kato H, Takeuchi M, Tohyama M, Yamamoto T. Specific expressions of Fyn and Lyn, lymphocyte antigen receptor-associated tyrosine kinases, in the central nervous system. Brain Research. Molecular Brain Research. 16: 303-10. PMID 1337939 DOI: 10.1016/0169-328X(92)90239-8  1
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