| Year |
Citation |
Score |
| 2024 |
Shin TW, Wang H, Zhang C, An B, Lu Y, Zhang E, Lu X, Karagiannis ED, Kang JS, Emenari A, Symvoulidis P, Asano S, Lin L, Costa EK, Marblestone AH, ... ... Tsai LH, et al. Dense, Continuous Membrane Labeling and Expansion Microscopy Visualization of Ultrastructure in Tissues. Biorxiv : the Preprint Server For Biology. PMID 38496681 DOI: 10.1101/2024.03.07.583776 |
0.426 |
|
| 2024 |
Murdock MH, Yang CY, Sun N, Pao PC, Blanco-Duque C, Kahn MC, Kim T, Lavoie NS, Victor MB, Islam MR, Galiana F, Leary N, Wang S, Bubnys A, Ma E, ... ... Tsai LH, et al. Multisensory gamma stimulation promotes glymphatic clearance of amyloid. Nature. PMID 38418876 DOI: 10.1038/s41586-024-07132-6 |
0.5 |
|
| 2023 |
Ralvenius WT, Mungenast AE, Woolf H, Huston MM, Gillingham TZ, Godin SK, Penney J, Cam HP, Gao F, Fernandez CG, Czako B, Lightfoot Y, Ray WJ, Beckmann A, Goate AM, ... ... Tsai LH, et al. A novel molecular class that recruits HDAC/MECP2 complexes to PU.1 motifs reduces neuroinflammation. The Journal of Experimental Medicine. 220. PMID 37642942 DOI: 10.1084/jem.20222105 |
0.71 |
|
| 2023 |
Suk HJ, Buie N, Xu G, Banerjee A, Boyden ES, Tsai LH. Vibrotactile stimulation at gamma frequency mitigates pathology related to neurodegeneration and improves motor function. Frontiers in Aging Neuroscience. 15: 1129510. PMID 37273653 DOI: 10.3389/fnagi.2023.1129510 |
0.479 |
|
| 2023 |
Ramamurthy E, Welch G, Cheng J, Yuan Y, Gunsalus L, Bennett DA, Tsai LH, Pfenning AR. Cell type-specific histone acetylation profiling of Alzheimer's disease subjects and integration with genetics. Frontiers in Molecular Neuroscience. 15: 948456. PMID 36683855 DOI: 10.3389/fnmol.2022.948456 |
0.795 |
|
| 2022 |
Chan D, Suk HJ, Jackson BL, Milman NP, Stark D, Klerman EB, Kitchener E, Fernandez Avalos VS, de Weck G, Banerjee A, Beach SD, Blanchard J, Stearns C, Boes AD, Uitermarkt B, ... ... Tsai LH, et al. Gamma frequency sensory stimulation in mild probable Alzheimer's dementia patients: Results of feasibility and pilot studies. Plos One. 17: e0278412. PMID 36454969 DOI: 10.1371/journal.pone.0278412 |
0.462 |
|
| 2022 |
Colombo G, Cubero RJA, Kanari L, Venturino A, Schulz R, Scolamiero M, Agerberg J, Mathys H, Tsai LH, Chachólski W, Hess K, Siegert S. A tool for mapping microglial morphology, morphOMICs, reveals brain-region and sex-dependent phenotypes. Nature Neuroscience. 25: 1379-1393. PMID 36180790 DOI: 10.1038/s41593-022-01167-6 |
0.774 |
|
| 2022 |
Welch GM, Boix CA, Schmauch E, Davila-Velderrain J, Victor MB, Dileep V, Bozzelli PL, Su Q, Cheng JD, Lee A, Leary NS, Pfenning AR, Kellis M, Tsai LH. Neurons burdened by DNA double-strand breaks incite microglia activation through antiviral-like signaling in neurodegeneration. Science Advances. 8: eabo4662. PMID 36170369 DOI: 10.1126/sciadv.abo4662 |
0.806 |
|
| 2022 |
Sarkar D, Kang J, Wassie AT, Schroeder ME, Peng Z, Tarr TB, Tang AH, Niederst ED, Young JZ, Su H, Park D, Yin P, Tsai LH, Blanpied TA, Boyden ES. Revealing nanostructures in brain tissue via protein decrowding by iterative expansion microscopy. Nature Biomedical Engineering. PMID 36038771 DOI: 10.1038/s41551-022-00912-3 |
0.636 |
|
| 2021 |
Pao PC, Tsai LH. Three decades of Cdk5. Journal of Biomedical Science. 28: 79. PMID 34814918 DOI: 10.1186/s12929-021-00774-y |
0.309 |
|
| 2021 |
Dele-Oni DO, Christianson KE, Egri SB, Vaca Jacome AS, DeRuff KC, Mullahoo J, Sharma V, Davison D, Ko T, Bula M, Blanchard J, Young JZ, Litichevskiy L, Lu X, Lam D, ... ... Tsai LH, et al. Proteomic profiling dataset of chemical perturbations in multiple biological backgrounds. Scientific Data. 8: 226. PMID 34433823 DOI: 10.1038/s41597-021-01008-4 |
0.514 |
|
| 2020 |
Marco A, Meharena HS, Dileep V, Raju RM, Davila-Velderrain J, Zhang AL, Adaikkan C, Young JZ, Gao F, Kellis M, Tsai LH. Mapping the epigenomic and transcriptomic interplay during memory formation and recall in the hippocampal engram ensemble. Nature Neuroscience. PMID 33020654 DOI: 10.1038/s41593-020-00717-0 |
0.566 |
|
| 2020 |
Wan YW, Al-Ouran R, Mangleburg CG, Perumal TM, Lee TV, Allison K, Swarup V, Funk CC, Gaiteri C, Allen M, Wang M, Neuner SM, Kaczorowski CC, Philip VM, Howell GR, ... ... Tsai LH, et al. Meta-Analysis of the Alzheimer's Disease Human Brain Transcriptome and Functional Dissection in Mouse Models. Cell Reports. 32: 107908. PMID 32668255 DOI: 10.1016/J.Celrep.2020.107908 |
0.36 |
|
| 2020 |
Blanchard JW, Bula M, Davila-Velderrain J, Akay LA, Zhu L, Frank A, Victor MB, Bonner JM, Mathys H, Lin YT, Ko T, Bennett DA, Cam HP, Kellis M, Tsai LH. Reconstruction of the human blood-brain barrier in vitro reveals a pathogenic mechanism of APOE4 in pericytes. Nature Medicine. PMID 32514169 DOI: 10.1038/S41591-020-0886-4 |
0.371 |
|
| 2020 |
Pao PC, Patnaik D, Watson LA, Gao F, Pan L, Wang J, Adaikkan C, Penney J, Cam HP, Huang WC, Pantano L, Lee A, Nott A, Phan TX, Gjoneska E, ... ... Tsai LH, et al. HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer's disease. Nature Communications. 11: 2484. PMID 32424276 DOI: 10.1038/S41467-020-16361-Y |
0.75 |
|
| 2020 |
Kiroski I, Jiang Y, Gavrilovici C, Gao F, Lee S, Scantlebury MH, Vandal M, Park SK, Tsai LH, Teskey GC, Rho JM, Nguyen MD. Reelin Improves Cognition and Extends the Lifespan of Mutant Ndel1 Mice with Postnatal CA1 Hippocampus Deterioration. Cerebral Cortex (New York, N.Y. : 1991). PMID 32328622 DOI: 10.1093/Cercor/Bhaa088 |
0.367 |
|
| 2019 |
Gail Canter R, Huang WC, Choi H, Wang J, Ashley Watson L, Yao CG, Abdurrob F, Bousleiman SM, Young JZ, Bennett DA, Delalle I, Chung K, Tsai LH. 3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice. Communications Biology. 2: 360. PMID 31925184 DOI: 10.1038/s42003-019-0599-8 |
0.556 |
|
| 2019 |
Adaikkan C, Tsai LH. Gamma Entrainment: Impact on Neurocircuits, Glia, and Therapeutic Opportunities. Trends in Neurosciences. PMID 31836315 DOI: 10.1016/j.tins.2019.11.001 |
0.336 |
|
| 2019 |
Gail Canter R, Huang WC, Choi H, Wang J, Ashley Watson L, Yao CG, Abdurrob F, Bousleiman SM, Young JZ, Bennett DA, Delalle I, Chung K, Tsai LH. 3D mapping reveals network-specific amyloid progression and subcortical susceptibility in mice. Communications Biology. 2: 360. PMID 31602409 DOI: 10.1038/s42003-019-0599-8 |
0.556 |
|
| 2019 |
Penney J, Ralvenius WT, Tsai LH. Modeling Alzheimer's disease with iPSC-derived brain cells. Molecular Psychiatry. PMID 31391546 DOI: 10.1038/s41380-019-0468-3 |
0.346 |
|
| 2019 |
Mathys H, Davila-Velderrain J, Peng Z, Gao F, Mohammadi S, Young JZ, Menon M, He L, Abdurrob F, Jiang X, Martorell AJ, Ransohoff RM, Hafler BP, Bennett DA, Kellis M, ... Tsai LH, et al. Author Correction: Single-cell transcriptomic analysis of Alzheimer's disease. Nature. PMID 31209304 DOI: 10.1038/S41586-019-1329-6 |
0.772 |
|
| 2019 |
Fan Q, Gayen M, Singh N, Gao F, He W, Hu X, Tsai LH, Yan R. The intracellular domain of CX3CL1 regulates adult neurogenesis and Alzheimer's amyloid pathology. The Journal of Experimental Medicine. PMID 31209068 DOI: 10.1084/Jem.20182238 |
0.376 |
|
| 2019 |
Pao PC, Penney J, Tsai LH. Examining the Role of HDACs in DNA Double-Strand Break Repair in Neurons. Methods in Molecular Biology (Clifton, N.J.). 1983: 225-234. PMID 31087301 DOI: 10.1007/978-1-4939-9434-2_13 |
0.305 |
|
| 2019 |
Adaikkan C, Middleton SJ, Marco A, Pao PC, Mathys H, Kim DN, Gao F, Young JZ, Suk HJ, Boyden ES, McHugh TJ, Tsai LH. Gamma Entrainment Binds Higher-Order Brain Regions and Offers Neuroprotection. Neuron. PMID 31076275 DOI: 10.1016/j.neuron.2019.04.011 |
0.723 |
|
| 2019 |
Mathys H, Davila-Velderrain J, Peng Z, Gao F, Mohammadi S, Young JZ, Menon M, He L, Abdurrob F, Jiang X, Martorell AJ, Ransohoff RM, Hafler BP, Bennett DA, Kellis M, ... Tsai LH, et al. Single-cell transcriptomic analysis of Alzheimer's disease. Nature. PMID 31042697 DOI: 10.1038/S41586-019-1195-2 |
0.797 |
|
| 2019 |
Martorell AJ, Paulson AL, Suk HJ, Abdurrob F, Drummond GT, Guan W, Young JZ, Kim DN, Kritskiy O, Barker SJ, Mangena V, Prince SM, Brown EN, Chung K, Boyden ES, ... ... Tsai LH, et al. Multi-sensory Gamma Stimulation Ameliorates Alzheimer's-Associated Pathology and Improves Cognition. Cell. PMID 30879788 DOI: 10.1016/J.Cell.2019.02.014 |
0.786 |
|
| 2019 |
Blanchard JW, Tsai LH. Unraveling the Paradox of Statins with Human Neurons: New Leads in Alzheimer's Disease. Cell Stem Cell. 24: 347-349. PMID 30849361 DOI: 10.1016/j.stem.2019.02.003 |
0.333 |
|
| 2019 |
Amal H, Gong G, Gjoneska E, Lewis SM, Wishnok JS, Tsai LH, Tannenbaum SR. S-nitrosylation of E3 ubiquitin-protein ligase RNF213 alters non-canonical Wnt/Ca+2 signaling in the P301S mouse model of tauopathy. Translational Psychiatry. 9: 44. PMID 30696811 DOI: 10.1038/S41398-019-0388-7 |
0.376 |
|
| 2019 |
Klein HU, McCabe C, Gjoneska E, Sullivan SE, Kaskow BJ, Tang A, Smith RV, Xu J, Pfenning AR, Bernstein BE, Meissner A, Schneider JA, Mostafavi S, Tsai LH, Young-Pearse TL, et al. Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer's human brains. Nature Neuroscience. 22: 37-46. PMID 30559478 DOI: 10.1038/S41593-018-0291-1 |
0.357 |
|
| 2018 |
Penney J, Tsai LH. Elimination of senescent cells prevents neurodegeneration in mice. Nature. 562: 503-504. PMID 30349121 DOI: 10.1038/d41586-018-06677-7 |
0.315 |
|
| 2018 |
Singer AC, Martorell AJ, Douglas JM, Abdurrob F, Attokaren MK, Tipton J, Mathys H, Adaikkan C, Tsai LH. Noninvasive 40-Hz light flicker to recruit microglia and reduce amyloid beta load. Nature Protocols. PMID 30072722 DOI: 10.1038/S41596-018-0021-X |
0.784 |
|
| 2018 |
Singer AC, Martorell AJ, Douglas JM, Abdurrob F, Attokaren MK, Tipton J, Mathys H, Adaikkan C, Tsai LH. Noninvasive 40-Hz light flicker to recruit microglia and reduce amyloid beta load. Nature Protocols. PMID 30072722 DOI: 10.1038/S41596-018-0021-X |
0.784 |
|
| 2018 |
Iaccarino HF, Singer AC, Martorell AJ, Rudenko A, Gao F, Gillingham TZ, Mathys H, Seo J, Kritskiy O, Abdurrob F, Adaikkan C, Canter RG, Rueda R, Brown EN, Boyden ES, ... Tsai LH, et al. Author Correction: Gamma frequency entrainment attenuates amyloid load and modifies microglia. Nature. PMID 30046102 DOI: 10.1038/S41586-018-0351-4 |
0.76 |
|
| 2018 |
Lin YT, Seo J, Gao F, Feldman HM, Wen HL, Penney J, Cam HP, Gjoneska E, Raja WK, Cheng J, Rueda R, Kritskiy O, Abdurrob F, Peng Z, Milo B, ... ... Tsai LH, et al. APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types. Neuron. 98: 1294. PMID 29953873 DOI: 10.1016/j.neuron.2018.06.011 |
0.793 |
|
| 2018 |
Zhao WN, Ghosh B, Tyler M, Lalonde J, Joseph NF, Kosaric N, Fass DM, Tsai LH, Mazitschek R, Haggarty SJ. Class I Histone Deacetylase Inhibition by Tianeptinaline Modulates Neuroplasticity and Enhances Memory. Acs Chemical Neuroscience. PMID 29932631 DOI: 10.1021/Acschemneuro.8B00116 |
0.795 |
|
| 2018 |
Lin YT, Seo J, Gao F, Feldman HM, Wen HL, Penney J, Cam HP, Gjoneska E, Raja WK, Cheng J, Rueda R, Kritskiy O, Abdurrob F, Peng Z, Milo B, ... ... Tsai LH, et al. APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types. Neuron. PMID 29861287 DOI: 10.1016/J.Neuron.2018.05.008 |
0.81 |
|
| 2018 |
Litichevskiy L, Peckner R, Abelin JG, Asiedu JK, Creech AL, Davis JF, Davison D, Dunning CM, Egertson JD, Egri S, Gould J, Ko T, Johnson SA, Lahr DL, Lam D, ... ... Tsai LH, et al. A Library of Phosphoproteomic and Chromatin Signatures for Characterizing Cellular Responses to Drug Perturbations. Cell Systems. PMID 29655704 DOI: 10.1016/J.Cels.2018.03.012 |
0.764 |
|
| 2017 |
Mathys H, Adaikkan C, Gao F, Young JZ, Manet E, Hemberg M, De Jager PL, Ransohoff RM, Regev A, Tsai LH. Temporal Tracking of Microglia Activation in Neurodegeneration at Single-Cell Resolution. Cell Reports. 21: 366-380. PMID 29020624 DOI: 10.1016/J.Celrep.2017.09.039 |
0.562 |
|
| 2017 |
Seo J, Kritskiy O, Watson LA, Barker SJ, Dey D, Raja WK, Lin YT, Ko T, Cho S, Penney J, Silva MC, Sheridan SD, Lucente D, Gusella JF, Dickerson BC, ... ... Tsai LH, et al. Inhibition of p25/Cdk5 attenuates tauopathy in mouse and iPSC models of frontotemporal dementia. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 28912154 DOI: 10.1523/Jneurosci.0621-17.2017 |
0.377 |
|
| 2017 |
Penney J, Seo J, Kritskiy O, Elmsaouri S, Gao F, Pao PC, Su SC, Tsai LH. Loss of Protein Arginine Methyltransferase 8 Alters Synapse Composition and Function, Resulting in Behavioral Defects. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 37: 8655-8666. PMID 28878098 DOI: 10.1523/JNEUROSCI.0591-17.2017 |
0.399 |
|
| 2017 |
Yamakawa H, Cheng J, Penney J, Gao F, Rueda R, Wang J, Yamakawa S, Kritskiy O, Gjoneska E, Tsai LH. The Transcription Factor Sp3 Cooperates with HDAC2 to Regulate Synaptic Function and Plasticity in Neurons. Cell Reports. 20: 1319-1334. PMID 28793257 DOI: 10.1016/j.celrep.2017.07.044 |
0.806 |
|
| 2017 |
Grossman N, Bono D, Dedic N, Kodandaramaiah SB, Rudenko A, Suk HJ, Cassara AM, Neufeld E, Kuster N, Tsai LH, Pascual-Leone A, Boyden ES. Noninvasive Deep Brain Stimulation via Temporally Interfering Electric Fields. Cell. 169: 1029-1041.e16. PMID 28575667 DOI: 10.1016/j.cell.2017.05.024 |
0.482 |
|
| 2017 |
Watson LA, Tsai LH. Molecular biology: Local metabolites linked to memory. Nature. PMID 28562586 DOI: 10.1038/nature22498 |
0.38 |
|
| 2017 |
Shukla V, Seo J, Binukumar BK, Amin ND, Reddy P, Grant P, Kuntz S, Kesavapany S, Steiner J, Mishra SK, Tsai LH, Pant HC. TFP5, a Peptide Inhibitor of Aberrant and Hyperactive Cdk5/p25, Attenuates Pathological Phenotypes and Restores Synaptic Function in CK-p25Tg Mice. Journal of Alzheimer's Disease : Jad. 56: 335-349. PMID 28085018 DOI: 10.3233/Jad-160916 |
0.412 |
|
| 2017 |
Tsai L. Epigenetic Mechanisms Regulating Social Behaviors Relevant to The Autism Spectrum Disorders European Neuropsychopharmacology. 27. DOI: 10.1016/J.Euroneuro.2016.09.592 |
0.315 |
|
| 2016 |
Watson LA, Tsai LH. In the loop: how chromatin topology links genome structure to function in mechanisms underlying learning and memory. Current Opinion in Neurobiology. 43: 48-55. PMID 28024185 DOI: 10.1016/j.conb.2016.12.002 |
0.387 |
|
| 2016 |
Mathew RS, Tatarakis A, Rudenko A, Johnson-Venkatesh EM, Yang YJ, Murphy EA, Todd TP, Schepers SP, Siuti N, Martorell AJ, Falls WA, Hammack SE, Walsh CA, Tsai LH, Umemori H, et al. Inhibition of memory by a microRNA negative feedback loop that downregulates SNARE-mediated vesicle transport. Elife. 5. PMID 28001126 DOI: 10.7554/Elife.22467 |
0.787 |
|
| 2016 |
Iaccarino HF, Singer AC, Martorell AJ, Rudenko A, Gao F, Gillingham TZ, Mathys H, Seo J, Kritskiy O, Abdurrob F, Adaikkan C, Canter RG, Rueda R, Brown EN, Boyden ES, ... Tsai LH, et al. Gamma frequency entrainment attenuates amyloid load and modifies microglia. Nature. 540: 230-235. PMID 27929004 DOI: 10.1038/Nature20587 |
0.793 |
|
| 2016 |
Canter RG, Penney J, Tsai LH. The road to restoring neural circuits for the treatment of Alzheimer's disease. Nature. 539: 187-196. PMID 27830780 DOI: 10.1038/nature20412 |
0.321 |
|
| 2016 |
Durak O, Gao F, Kaeser-Woo YJ, Rueda R, Martorell AJ, Nott A, Liu CY, Watson LA, Tsai LH. Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling. Nature Neuroscience. PMID 27694995 DOI: 10.1038/Nn.4400 |
0.791 |
|
| 2016 |
Raja WK, Mungenast AE, Lin YT, Ko T, Abdurrob F, Seo J, Tsai LH. Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer's Disease Phenotypes. Plos One. 11: e0161969. PMID 27622770 DOI: 10.1371/Journal.Pone.0161969 |
0.721 |
|
| 2016 |
Siegert S, Seo J, Kwon EJ, Rudenko A, Cho S, Wang W, Flood Z, Martorell AJ, Ericsson M, Mungenast AE, Tsai LH. Addendum: The schizophrenia risk gene product miR-137 alters presynaptic plasticity. Nature Neuroscience. 19: 1115. PMID 27459408 DOI: 10.1038/Nn0816-1115C |
0.757 |
|
| 2016 |
Nott A, Cheng J, Gao F, Lin YT, Gjoneska E, Ko T, Minhas P, Zamudio AV, Meng J, Zhang F, Jin P, Tsai LH. Histone deacetylase 3 associates with MeCP2 to regulate FOXO and social behavior. Nature Neuroscience. PMID 27428650 DOI: 10.1038/Nn.4347 |
0.807 |
|
| 2016 |
Anda FC, Madabhushi R, Rei D, Meng J, Gräff J, Durak O, Meletis K, Richter M, Schwanke B, Mungenast A, Tsai LH. Cortical neurons gradually attain a post-mitotic state. Cell Research. PMID 27325298 DOI: 10.1038/Cr.2016.76 |
0.803 |
|
| 2016 |
Zou D, Zhou Y, Liu L, Dong F, Shu T, Zhou Y, Tsai LH, Mao Y. Transient enhancement of proliferation of neural progenitors and impairment of their long-term survival in p25 transgenic mice. Oncotarget. PMID 27283769 DOI: 10.18632/oncotarget.9834 |
0.804 |
|
| 2016 |
Seneviratne U, Nott A, Bhat VB, Ravindra KC, Wishnok JS, Tsai LH, Tannenbaum SR. S-nitrosation of proteins relevant to Alzheimer's disease during early stages of neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. PMID 27035958 DOI: 10.1073/Pnas.1521318113 |
0.336 |
|
| 2016 |
Tsai LH, Siegert S. How MicroRNAs Are Involved in Splitting the Mind. Jama Psychiatry. PMID 26963490 DOI: 10.1001/jamapsychiatry.2015.3144 |
0.584 |
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| 2016 |
Ghosh B, Zhao WN, Reis SA, Patnaik D, Fass DM, Tsai LH, Mazitschek R, Haggarty SJ. Dissecting structure-activity-relationships of crebinostat: Brain penetrant HDAC inhibitors for neuroepigenetic regulation. Bioorganic & Medicinal Chemistry Letters. PMID 26804233 DOI: 10.1016/J.Bmcl.2016.01.022 |
0.409 |
|
| 2016 |
Mathew RS, Tatarakis A, Rudenko A, Johnson-Venkatesh EM, Yang YJ, Murphy EA, Todd TP, Schepers ST, Siuti N, Martorell AJ, Falls WA, Hammack SE, Walsh CA, Tsai L, Umemori H, et al. Author response: A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory Elife. DOI: 10.7554/Elife.22467.030 |
0.769 |
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| 2015 |
Penney J, Tsai LH. JAKMIP1: Translating the Message for Social Behavior. Neuron. 88: 1070-2. PMID 26687214 DOI: 10.1016/j.neuron.2015.12.003 |
0.355 |
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| 2015 |
Mungenast AE, Siegert S, Tsai LH. Modeling Alzheimer's disease with human induced pluripotent stem (iPS) cells. Molecular and Cellular Neurosciences. PMID 26657644 DOI: 10.1016/J.Mcn.2015.11.010 |
0.784 |
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| 2015 |
Sheng Y, Zhang L, Su SC, Tsai LH, Julius Zhu J. Cdk5 is a New Rapid Synaptic Homeostasis Regulator Capable of Initiating the Early Alzheimer-Like Pathology. Cerebral Cortex (New York, N.Y. : 1991). PMID 26088971 DOI: 10.1093/Cercor/Bhv032 |
0.389 |
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| 2015 |
Madabhushi R, Gao F, Pfenning AR, Pan L, Yamakawa S, Seo J, Rueda R, Phan TX, Yamakawa H, Pao PC, Stott RT, Gjoneska E, Nott A, Cho S, Kellis M, Tsai LH, et al. Activity-Induced DNA Breaks Govern the Expression of Neuronal Early-Response Genes. Cell. 161: 1592-605. PMID 26052046 DOI: 10.1016/J.Cell.2015.05.032 |
0.748 |
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| 2015 |
Siegert S, Seo J, Kwon EJ, Rudenko A, Cho S, Wang W, Flood Z, Martorell AJ, Ericsson M, Mungenast AE, Tsai LH. The schizophrenia risk gene product miR-137 alters presynaptic plasticity. Nature Neuroscience. 18: 1008-16. PMID 26005852 DOI: 10.1016/J.Euroneuro.2016.09.595 |
0.773 |
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| 2015 |
Rei D, Mason X, Seo J, Gräff J, Rudenko A, Wang J, Rueda R, Siegert S, Cho S, Canter RG, Mungenast AE, Deisseroth K, Tsai LH. Basolateral amygdala bidirectionally modulates stress-induced hippocampal learning and memory deficits through a p25/Cdk5-dependent pathway. Proceedings of the National Academy of Sciences of the United States of America. 112: 7291-6. PMID 25995364 DOI: 10.1073/Pnas.1415845112 |
0.788 |
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| 2015 |
Murn J, Zarnack K, Yang YJ, Durak O, Murphy EA, Cheloufi S, Gonzalez DM, Teplova M, Curk T, Zuber J, Patel DJ, Ule J, Luscombe NM, Tsai LH, Walsh CA, et al. Control of a neuronal morphology program by an RNA-binding zinc finger protein, Unkempt. Genes & Development. 29: 501-12. PMID 25737280 DOI: 10.1101/Gad.258483.115 |
0.78 |
|
| 2015 |
Nott A, Cho S, Seo J, Tsai LH. HDAC2 expression in parvalbumin interneurons regulates synaptic plasticity in the mouse visual cortex. Neuroepigenetics. 1: 34-40. PMID 25705589 DOI: 10.1016/j.nepig.2014.10.005 |
0.349 |
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| 2015 |
Gjoneska E, Pfenning AR, Mathys H, Quon G, Kundaje A, Tsai LH, Kellis M. Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer's disease. Nature. 518: 365-9. PMID 25693568 DOI: 10.1038/Nature14252 |
0.383 |
|
| 2015 |
Rudenko A, Seo J, Hu J, Su SC, de Anda FC, Durak O, Ericsson M, Carlén M, Tsai LH. Loss of cyclin-dependent kinase 5 from parvalbumin interneurons leads to hyperinhibition, decreased anxiety, and memory impairment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 2372-83. PMID 25673832 DOI: 10.1523/Jneurosci.0969-14.2015 |
0.808 |
|
| 2015 |
Wagner FF, Zhang YL, Fass DM, Joseph N, Gale JP, Weïwer M, McCarren P, Fisher SL, Kaya T, Zhao WN, Reis SA, Hennig KM, Thomas M, Lemercier BC, Lewis MC, ... ... Tsai LH, et al. Kinetically Selective Inhibitors of Histone Deacetylase 2 (HDAC2) as Cognition Enhancers. Chemical Science (Royal Society of Chemistry : 2010). 6: 804-815. PMID 25642316 DOI: 10.1039/C4Sc02130D |
0.798 |
|
| 2015 |
Yoshimizu T, Pan JQ, Mungenast AE, Madison JM, Su S, Ketterman J, Ongur D, McPhie D, Cohen B, Perlis R, Tsai LH. Functional implications of a psychiatric risk variant within CACNA1C in induced human neurons. Molecular Psychiatry. 20: 284. PMID 25623946 DOI: 10.1038/mp.2014.181 |
0.701 |
|
| 2015 |
Yoshimizu T, Pan JQ, Mungenast AE, Madison JM, Su S, Ketterman J, Ongur D, McPhie D, Cohen B, Perlis R, Tsai LH. Functional implications of a psychiatric risk variant within CACNA1C in induced human neurons. Molecular Psychiatry. 20: 162-9. PMID 25403839 DOI: 10.1038/Mp.2014.143 |
0.722 |
|
| 2015 |
Durak O, de Anda FC, Singh KK, Leussis MP, Petryshen TL, Sklar P, Tsai LH. Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of β-catenin. Molecular Psychiatry. 20: 388-97. PMID 24821222 DOI: 10.1038/Mp.2014.42 |
0.763 |
|
| 2014 |
Penney J, Tsai LH. Histone deacetylases in memory and cognition. Science Signaling. 7: re12. PMID 25492968 DOI: 10.1126/scisignal.aaa0069 |
0.376 |
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| 2014 |
Pan L, Penney J, Tsai LH. Chromatin regulation of DNA damage repair and genome integrity in the central nervous system. Journal of Molecular Biology. 426: 3376-88. PMID 25128619 DOI: 10.1016/j.jmb.2014.08.001 |
0.329 |
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| 2014 |
Bero AW, Meng J, Cho S, Shen AH, Canter RG, Ericsson M, Tsai LH. Early remodeling of the neocortex upon episodic memory encoding. Proceedings of the National Academy of Sciences of the United States of America. 111: 11852-7. PMID 25071187 DOI: 10.1073/Pnas.1408378111 |
0.334 |
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| 2014 |
Durak O, Tsai LH. Human induced pluripotent stem cells: now open to discovery. Cell Stem Cell. 15: 4-6. PMID 24996162 DOI: 10.1016/J.Stem.2014.06.014 |
0.754 |
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| 2014 |
Seo J, Tsai LH. Neuronal differentiation: 5-HT6R can do it alone. Nature Chemical Biology. 10: 488-9. PMID 24937065 DOI: 10.1038/nchembio.1557 |
0.365 |
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| 2014 |
Seo J, Giusti-RodrÃguez P, Zhou Y, Rudenko A, Cho S, Ota KT, Park C, Patzke H, Madabhushi R, Pan L, Mungenast AE, Guan JS, Delalle I, Tsai LH. Activity-dependent p25 generation regulates synaptic plasticity and Aβ-induced cognitive impairment. Cell. 157: 486-98. PMID 24725413 DOI: 10.1016/J.Cell.2014.01.065 |
0.782 |
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| 2014 |
Rudenko A, Tsai LH. Epigenetic modifications in the nervous system and their impact upon cognitive impairments. Neuropharmacology. 80: 70-82. PMID 24495398 DOI: 10.1016/j.neuropharm.2014.01.043 |
0.391 |
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| 2014 |
Gräff J, Joseph NF, Horn ME, Samiei A, Meng J, Seo J, Rei D, Bero AW, Phan TX, Wagner F, Holson E, Xu J, Sun J, Neve RL, Mach RH, ... ... Tsai LH, et al. Epigenetic priming of memory updating during reconsolidation to attenuate remote fear memories. Cell. 156: 261-76. PMID 24439381 DOI: 10.1016/J.Cell.2013.12.020 |
0.773 |
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| 2014 |
de Anda FC, Rosario AL, Durak O, Tran T, Gräff J, Meletis K, Rei D, Soda T, Madabhushi R, Ginty DD, Kolodkin AL, Tsai L. Erratum: Corrigendum: Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex Nature Neuroscience. 17: 1840-1840. DOI: 10.1038/Nn1214-1840A |
0.76 |
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| 2013 |
Chung CY, Khurana V, Auluck PK, Tardiff DF, Mazzulli JR, Soldner F, Baru V, Lou Y, Freyzon Y, Cho S, Mungenast AE, Muffat J, Mitalipova M, Pluth MD, Jui NT, ... ... Tsai LH, et al. Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons. Science (New York, N.Y.). 342: 983-7. PMID 24158904 DOI: 10.1126/Science.1245296 |
0.712 |
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| 2013 |
Pozo K, Castro-Rivera E, Tan C, Plattner F, Schwach G, Siegl V, Meyer D, Guo A, Gundara J, Mettlach G, Richer E, Guevara JA, Ning L, Gupta A, Hao G, ... Tsai LH, et al. The role of Cdk5 in neuroendocrine thyroid cancer. Cancer Cell. 24: 499-511. PMID 24135281 DOI: 10.1016/J.Ccr.2013.08.027 |
0.509 |
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| 2013 |
Bosutti A, Qi J, Pennucci R, Bolton D, Matou S, Ali K, Tsai LH, Krupinski J, Petcu EB, Montaner J, Al Baradie R, Caccuri F, Caruso A, Alessandri G, Kumar S, et al. Targeting p35/Cdk5 signalling via CIP-peptide promotes angiogenesis in hypoxia. Plos One. 8: e75538. PMID 24098701 DOI: 10.1371/journal.pone.0075538 |
0.401 |
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| 2013 |
Su SC, Rudenko A, Cho S, Tsai LH. Forebrain-specific deletion of Cdk5 in pyramidal neurons results in mania-like behavior and cognitive impairment. Neurobiology of Learning and Memory. 105: 54-62. PMID 23850563 DOI: 10.1016/j.nlm.2013.06.016 |
0.393 |
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| 2013 |
Zhang X, Hernandez I, Rei D, Mair W, Laha JK, Cornwell ME, Cuny GD, Tsai LH, Steen JA, Kosik KS. Diaminothiazoles modify Tau phosphorylation and improve the tauopathy in mouse models. The Journal of Biological Chemistry. 288: 22042-56. PMID 23737518 DOI: 10.1074/Jbc.M112.436402 |
0.349 |
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| 2013 |
Gräff J, Kahn M, Samiei A, Gao J, Ota KT, Rei D, Tsai LH. A dietary regimen of caloric restriction or pharmacological activation of SIRT1 to delay the onset of neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 8951-60. PMID 23699506 DOI: 10.1523/Jneurosci.5657-12.2013 |
0.311 |
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| 2013 |
Soda T, Frank C, Ishizuka K, Baccarella A, Park YU, Flood Z, Park SK, Sawa A, Tsai LH. DISC1-ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1. Molecular Psychiatry. 18: 898-908. PMID 23587879 DOI: 10.1038/mp.2013.38 |
0.554 |
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| 2013 |
Sirko S, Behrendt G, Johansson PA, Tripathi P, Costa M, Bek S, Heinrich C, Tiedt S, Colak D, Dichgans M, Fischer IR, Plesnila N, Staufenbiel M, Haass C, Snapyan M, ... ... Tsai LH, et al. Reactive glia in the injured brain acquire stem cell properties in response to sonic hedgehog. [corrected]. Cell Stem Cell. 12: 426-39. PMID 23561443 DOI: 10.1016/J.Stem.2013.01.019 |
0.369 |
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| 2013 |
Gräff J, Tsai LH. Histone acetylation: molecular mnemonics on the chromatin. Nature Reviews. Neuroscience. 14: 97-111. PMID 23324667 DOI: 10.1038/Nrn3427 |
0.303 |
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| 2013 |
Fass DM, Reis SA, Ghosh B, Hennig KM, Joseph NF, Zhao WN, Nieland TJ, Guan JS, Kuhnle CE, Tang W, Barker DD, Mazitschek R, Schreiber SL, Tsai LH, Haggarty SJ. Crebinostat: a novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity. Neuropharmacology. 64: 81-96. PMID 22771460 DOI: 10.1016/J.Neuropharm.2012.06.043 |
0.814 |
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| 2013 |
Soda T, Tsai L. Colocalization of PDE4D9 and DISC1 in cultured hippocampal neurons Molecular Psychiatry. 18: 845-845. DOI: 10.1038/mp.2013.88 |
0.487 |
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| 2012 |
Zhao WN, Cheng C, Theriault KM, Sheridan SD, Tsai LH, Haggarty SJ. A high-throughput screen for Wnt/β-catenin signaling pathway modulators in human iPSC-derived neural progenitors. Journal of Biomolecular Screening. 17: 1252-63. PMID 22923789 DOI: 10.1177/1087057112456876 |
0.31 |
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| 2012 |
Su SC, Seo J, Pan JQ, Samuels BA, Rudenko A, Ericsson M, Neve RL, Yue DT, Tsai LH. Regulation of N-type voltage-gated calcium channels and presynaptic function by cyclin-dependent kinase 5. Neuron. 75: 675-87. PMID 22920258 DOI: 10.1016/j.neuron.2012.06.023 |
0.622 |
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| 2012 |
de Anda FC, Rosario AL, Durak O, Tran T, Gräff J, Meletis K, Rei D, Soda T, Madabhushi R, Ginty DD, Kolodkin AL, Tsai LH. Autism spectrum disorder susceptibility gene TAOK2 affects basal dendrite formation in the neocortex. Nature Neuroscience. 15: 1022-31. PMID 22683681 DOI: 10.1038/Nn.3141 |
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| 2012 |
Gräff J, Rei D, Guan JS, Wang WY, Seo J, Hennig KM, Nieland TJ, Fass DM, Kao PF, Kahn M, Su SC, Samiei A, Joseph N, Haggarty SJ, Delalle I, ... Tsai LH, et al. An epigenetic blockade of cognitive functions in the neurodegenerating brain. Nature. 483: 222-6. PMID 22388814 DOI: 10.1038/Nature10849 |
0.8 |
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| 2012 |
Mungenast AE, Tsai LH. Cognitive function in health and disease: the role of epigenetic mechanisms. Neuro-Degenerative Diseases. 10: 191-4. PMID 22301371 DOI: 10.1159/000334602 |
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| 2012 |
Carlén M, Meletis K, Siegle JH, Cardin JA, Futai K, Vierling-Claassen D, Rühlmann C, Jones SR, Deisseroth K, Sheng M, Moore CI, Tsai LH. A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior. Molecular Psychiatry. 17: 537-48. PMID 21468034 DOI: 10.1038/Mp.2011.31 |
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| 2011 |
Siegle JH, Carlen M, Meletis K, Tsai LH, Moore CI, Ritt J. Chronically implanted hyperdrive for cortical recording and optogenetic control in behaving mice. Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Annual Conference. 2011: 7529-32. PMID 22256080 DOI: 10.1109/IEMBS.2011.6091856 |
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| 2011 |
Singh KK, De Rienzo G, Drane L, Mao Y, Flood Z, Madison J, Ferreira M, Bergen S, King C, Sklar P, Sive H, Tsai LH. Common DISC1 polymorphisms disrupt Wnt/GSK3β signaling and brain development. Neuron. 72: 545-58. PMID 22099458 DOI: 10.1016/J.Neuron.2011.09.030 |
0.723 |
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| 2011 |
Giusti-RodrÃguez P, Gao J, Gräff J, Rei D, Soda T, Tsai LH. Synaptic deficits are rescued in the p25/Cdk5 model of neurodegeneration by the reduction of β-secretase (BACE1). The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 15751-6. PMID 22049418 DOI: 10.1523/Jneurosci.3588-11.2011 |
0.608 |
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| 2011 |
Kim J, Su SC, Wang H, Cheng AW, Cassady JP, Lodato MA, Lengner CJ, Chung CY, Dawlaty MM, Tsai LH, Jaenisch R. Functional integration of dopaminergic neurons directly converted from mouse fibroblasts. Cell Stem Cell. 9: 413-9. PMID 22019014 DOI: 10.1016/J.Stem.2011.09.011 |
0.352 |
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| 2011 |
Guan JS, Su SC, Gao J, Joseph N, Xie Z, Zhou Y, Durak O, Zhang L, Zhu JJ, Clauser KR, Carr SA, Tsai LH. Cdk5 is required for memory function and hippocampal plasticity via the cAMP signaling pathway. Plos One. 6: e25735. PMID 21984943 DOI: 10.1371/Journal.Pone.0025735 |
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| 2011 |
de Anda FC, Tsai LH. Axon selection: From a polarized cytoplasm to a migrating neuron. Communicative & Integrative Biology. 4: 304-7. PMID 21980564 DOI: 10.4161/cib.4.3.14781 |
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| 2011 |
Buchman JJ, Durak O, Tsai LH. ASPM regulates Wnt signaling pathway activity in the developing brain. Genes & Development. 25: 1909-14. PMID 21937711 DOI: 10.1101/Gad.16830211 |
0.798 |
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| 2011 |
De Rienzo G, Bishop JA, Mao Y, Pan L, Ma TP, Moens CB, Tsai LH, Sive H. Disc1 regulates both β-catenin-mediated and noncanonical Wnt signaling during vertebrate embryogenesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 4184-97. PMID 21859895 DOI: 10.1096/Fj.11-186239 |
0.696 |
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| 2011 |
Pinheiro EM, Xie Z, Norovich AL, Vidaki M, Tsai LH, Gertler FB. Lpd depletion reveals that SRF specifies radial versus tangential migration of pyramidal neurons. Nature Cell Biology. 13: 989-95. PMID 21785421 DOI: 10.1038/Ncb2292 |
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| 2011 |
Su SC, Tsai LH. Cyclin-dependent kinases in brain development and disease. Annual Review of Cell and Developmental Biology. 27: 465-91. PMID 21740229 DOI: 10.1146/annurev-cellbio-092910-154023 |
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| 2011 |
Haggarty SJ, Tsai LH. Probing the role of HDACs and mechanisms of chromatin-mediated neuroplasticity. Neurobiology of Learning and Memory. 96: 41-52. PMID 21545841 DOI: 10.1016/J.Nlm.2011.04.009 |
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| 2011 |
Gräff J, Kim D, Dobbin MM, Tsai LH. Epigenetic regulation of gene expression in physiological and pathological brain processes. Physiological Reviews. 91: 603-49. PMID 21527733 DOI: 10.1152/Physrev.00012.2010 |
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| 2011 |
Mungenast AE, Tsai LH. Addressing the complex etiology of Alzheimers disease: The role of p25/Cdk5 Future Neurology. 6: 481-496. DOI: 10.2217/Fnl.11.22 |
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| 2010 |
Fischer A, Sananbenesi F, Mungenast A, Tsai LH. Targeting the correct HDAC(s) to treat cognitive disorders. Trends in Pharmacological Sciences. 31: 605-17. PMID 20980063 DOI: 10.1016/J.Tips.2010.09.003 |
0.744 |
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| 2010 |
Frank CL, Ge X, Xie Z, Zhou Y, Tsai LH. Control of activating transcription factor 4 (ATF4) persistence by multisite phosphorylation impacts cell cycle progression and neurogenesis. The Journal of Biological Chemistry. 285: 33324-37. PMID 20724472 DOI: 10.1074/Jbc.M110.140699 |
0.745 |
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| 2010 |
de Anda FC, Meletis K, Ge X, Rei D, Tsai LH. Centrosome motility is essential for initial axon formation in the neocortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 10391-406. PMID 20685982 DOI: 10.1523/Jneurosci.0381-10.2010 |
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| 2010 |
Singh KK, Ge X, Mao Y, Drane L, Meletis K, Samuels BA, Tsai LH. Dixdc1 is a critical regulator of DISC1 and embryonic cortical development. Neuron. 67: 33-48. PMID 20624590 DOI: 10.1016/J.Neuron.2010.06.002 |
0.81 |
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| 2010 |
Gao J, Wang WY, Mao YW, Gräff J, Guan JS, Pan L, Mak G, Kim D, Su SC, Tsai LH. A novel pathway regulates memory and plasticity via SIRT1 and miR-134. Nature. 466: 1105-9. PMID 20622856 DOI: 10.1038/Nature09271 |
0.76 |
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| 2010 |
Furuya T, Kim M, Lipinski M, Li J, Kim D, Lu T, Shen Y, Rameh L, Yankner B, Tsai LH, Yuan J. Negative regulation of Vps34 by Cdk mediated phosphorylation. Molecular Cell. 38: 500-11. PMID 20513426 DOI: 10.1016/J.Molcel.2010.05.009 |
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| 2010 |
Buchman JJ, Tseng HC, Zhou Y, Frank CL, Xie Z, Tsai LH. Cdk5rap2 interacts with pericentrin to maintain the neural progenitor pool in the developing neocortex. Neuron. 66: 386-402. PMID 20471352 DOI: 10.1016/J.Neuron.2010.03.036 |
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| 2010 |
MarÃn O, Valiente M, Ge X, Tsai LH. Guiding neuronal cell migrations. Cold Spring Harbor Perspectives in Biology. 2: a001834. PMID 20182622 DOI: 10.1101/Cshperspect.A001834 |
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| 2010 |
Ge X, Frank CL, Calderon de Anda F, Tsai LH. Hook3 interacts with PCM1 to regulate pericentriolar material assembly and the timing of neurogenesis. Neuron. 65: 191-203. PMID 20152126 DOI: 10.1016/J.Neuron.2010.01.011 |
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| 2010 |
Cardin JA, Carlén M, Meletis K, Knoblich U, Zhang F, Deisseroth K, Tsai LH, Moore CI. Targeted optogenetic stimulation and recording of neurons in vivo using cell-type-specific expression of Channelrhodopsin-2. Nature Protocols. 5: 247-54. PMID 20134425 DOI: 10.1038/Nprot.2009.228 |
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| 2010 |
Singh KK, Tsai LH. MicroTUB(B3)ules and brain development. Cell. 140: 30-2. PMID 20085703 DOI: 10.1016/j.cell.2009.12.038 |
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| 2010 |
Samuels BA, Tsai LH. Neuronal Motility and Structure: Cdk5 Pathways Encyclopedia of Neuroscience. 703-710. DOI: 10.1016/B978-008045046-9.00716-6 |
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| 2009 |
Malumbres M, Harlow E, Hunt T, Hunter T, Lahti JM, Manning G, Morgan DO, Tsai LH, Wolgemuth DJ. Cyclin-dependent kinases: a family portrait. Nature Cell Biology. 11: 1275-6. PMID 19884882 DOI: 10.1038/Ncb1109-1275 |
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| 2009 |
Davis DA, Wilson MH, Giraud J, Xie Z, Tseng HC, England C, Herscovitz H, Tsai LH, Delalle I. Capzb2 interacts with beta-tubulin to regulate growth cone morphology and neurite outgrowth. Plos Biology. 7: e1000208. PMID 19806181 DOI: 10.1371/Journal.Pbio.1000208 |
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| 2009 |
Kim D, Tsai LH. Linking cell cycle reentry and DNA damage in neurodegeneration. Annals of the New York Academy of Sciences. 1170: 674-9. PMID 19686210 DOI: 10.1111/j.1749-6632.2009.04105.x |
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| 2009 |
Orlando LR, Ayala R, Kett LR, Curley AA, Duffner J, Bragg DC, Tsai LH, Dunah AW, Young AB. Phosphorylation of the homer-binding domain of group I metabotropic glutamate receptors by cyclin-dependent kinase 5. Journal of Neurochemistry. 110: 557-69. PMID 19457112 DOI: 10.1111/J.1471-4159.2009.06139.X |
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| 2009 |
Frank CL, Tsai LH. Alternative functions of core cell cycle regulators in neuronal migration, neuronal maturation, and synaptic plasticity. Neuron. 62: 312-26. PMID 19447088 DOI: 10.1016/j.neuron.2009.03.029 |
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| 2009 |
Guan JS, Haggarty SJ, Giacometti E, Dannenberg JH, Joseph N, Gao J, Nieland TJ, Zhou Y, Wang X, Mazitschek R, Bradner JE, DePinho RA, Jaenisch R, Tsai LH. HDAC2 negatively regulates memory formation and synaptic plasticity. Nature. 459: 55-60. PMID 19424149 DOI: 10.1038/Nature07925 |
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| 2009 |
Cardin JA, Carlén M, Meletis K, Knoblich U, Zhang F, Deisseroth K, Tsai LH, Moore CI. Driving fast-spiking cells induces gamma rhythm and controls sensory responses. Nature. 459: 663-7. PMID 19396156 DOI: 10.1038/Nature08002 |
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| 2009 |
Mao Y, Ge X, Frank CL, Madison JM, Koehler AN, Doud MK, Tassa C, Berry EM, Soda T, Singh KK, Biechele T, Petryshen TL, Moon RT, Haggarty SJ, Tsai LH. Disrupted in schizophrenia 1 regulates neuronal progenitor proliferation via modulation of GSK3beta/beta-catenin signaling. Cell. 136: 1017-31. PMID 19303846 DOI: 10.1016/J.Cell.2008.12.044 |
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| 2008 |
Kim D, Frank CL, Dobbin MM, Tsunemoto RK, Tu W, Peng PL, Guan JS, Lee BH, Moy LY, Giusti P, Broodie N, Mazitschek R, Delalle I, Haggarty SJ, Neve RL, ... ... Tsai LH, et al. Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity. Neuron. 60: 803-17. PMID 19081376 DOI: 10.1016/J.Neuron.2008.10.015 |
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| 2008 |
Buchman JJ, Tsai LH. Putting a notch in our understanding of nuclear migration. Cell. 134: 912-4. PMID 18805082 DOI: 10.1016/J.Cell.2008.09.007 |
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| 2008 |
Shim SY, Samuels BA, Wang J, Neumayer G, Belzil C, Ayala R, Shi Y, Shi Y, Tsai LH, Nguyen MD. Ndel1 controls the dynein-mediated transport of vimentin during neurite outgrowth. The Journal of Biological Chemistry. 283: 12232-40. PMID 18303022 DOI: 10.1074/Jbc.M710200200 |
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| 2007 |
Samuels BA, Hsueh YP, Shu T, Liang H, Tseng HC, Hong CJ, Su SC, Volker J, Neve RL, Yue DT, Tsai LH. Cdk5 promotes synaptogenesis by regulating the subcellular distribution of the MAGUK family member CASK. Neuron. 56: 823-37. PMID 18054859 DOI: 10.1016/j.neuron.2007.09.035 |
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| 2007 |
Xie Z, Moy LY, Sanada K, Zhou Y, Buchman JJ, Tsai LH. Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool. Neuron. 56: 79-93. PMID 17920017 DOI: 10.1016/J.Neuron.2007.08.026 |
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| 2007 |
Choe EA, Liao L, Zhou JY, Cheng D, Duong DM, Jin P, Tsai LH, Peng J. Neuronal morphogenesis is regulated by the interplay between cyclin-dependent kinase 5 and the ubiquitin ligase mind bomb 1. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 9503-12. PMID 17728463 DOI: 10.1523/Jneurosci.1408-07.2007 |
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| 2007 |
Sananbenesi F, Fischer A, Wang X, Schrick C, Neve R, Radulovic J, Tsai LH. A hippocampal Cdk5 pathway regulates extinction of contextual fear. Nature Neuroscience. 10: 1012-9. PMID 17632506 DOI: 10.1038/Nn1943 |
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| 2007 |
Kim D, Nguyen MD, Dobbin MM, Fischer A, Sananbenesi F, Rodgers JT, Delalle I, Baur JA, Sui G, Armour SM, Puigserver P, Sinclair DA, Tsai LH. SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. The Embo Journal. 26: 3169-79. PMID 17581637 DOI: 10.1038/Sj.Emboj.7601758 |
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| 2007 |
Yip YP, Capriotti C, Drill E, Tsai LH, Yip JW. Cdk5 selectively affects the migration of different populations of neurons in the developing spinal cord. The Journal of Comparative Neurology. 503: 297-307. PMID 17492640 DOI: 10.1002/cne.21377 |
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| 2007 |
Fischer A, Sananbenesi F, Wang X, Dobbin M, Tsai LH. Recovery of learning and memory is associated with chromatin remodelling. Nature. 447: 178-82. PMID 17468743 DOI: 10.1038/Nature05772 |
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| 2007 |
Buchman JJ, Tsai LH. Spindle regulation in neural precursors of flies and mammals. Nature Reviews. Neuroscience. 8: 89-100. PMID 17228329 DOI: 10.1038/Nrn2058 |
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| 2007 |
Ayala R, Shu T, Tsai LH. Trekking across the brain: the journey of neuronal migration. Cell. 128: 29-43. PMID 17218253 DOI: 10.1016/j.cell.2006.12.021 |
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| 2006 |
Xie Z, Samuels BA, Tsai LH. Cyclin-dependent kinase 5 permits efficient cytoskeletal remodeling--a hypothesis on neuronal migration. Cerebral Cortex (New York, N.Y. : 1991). 16: i64-8. PMID 16766709 DOI: 10.1093/cercor/bhj170 |
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| 2006 |
Shu T, Tseng HC, Sapir T, Stern P, Zhou Y, Sanada K, Fischer A, Coquelle FM, Reiner O, Tsai LH. Doublecortin-like kinase controls neurogenesis by regulating mitotic spindles and M phase progression. Neuron. 49: 25-39. PMID 16387637 DOI: 10.1016/J.Neuron.2005.10.039 |
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| 2006 |
Kim D, Cruz JC, Moy LY, Sun X, Bronson RT, Shen J, Tsai L. P1-416: APP processing and cell cycle reentry signaling pathways are involved in p25/cdk5-mediated neurodegeneration Alzheimer's & Dementia. 2: S219-S220. DOI: 10.1016/J.Jalz.2006.05.795 |
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| 2005 |
Fischer A, Sananbenesi F, Pang PT, Lu B, Tsai LH. Opposing roles of transient and prolonged expression of p25 in synaptic plasticity and hippocampus-dependent memory. Neuron. 48: 825-38. PMID 16337919 DOI: 10.1016/J.Neuron.2005.10.033 |
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| 2005 |
Park SK, Nguyen MD, Fischer A, Luke MP, Affar el B, Dieffenbach PB, Tseng HC, Shi Y, Tsai LH. Par-4 links dopamine signaling and depression. Cell. 122: 275-87. PMID 16051151 DOI: 10.1016/J.Cell.2005.05.031 |
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| 2005 |
Sanada K, Tsai LH. G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors. Cell. 122: 119-31. PMID 16009138 DOI: 10.1016/j.cell.2005.05.009 |
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| 2005 |
Tsai LH, Gleeson JG. Nucleokinesis in neuronal migration. Neuron. 46: 383-8. PMID 15882636 DOI: 10.1016/J.Neuron.2005.04.013 |
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| 2004 |
Samuels BA, Tsai LH. Nucleokinesis illuminated. Nature Neuroscience. 7: 1169-70. PMID 15508010 DOI: 10.1038/nn1104-1169 |
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| 2004 |
Shu T, Ayala R, Nguyen MD, Xie Z, Gleeson JG, Tsai LH. Ndel1 operates in a common pathway with LIS1 and cytoplasmic dynein to regulate cortical neuronal positioning. Neuron. 44: 263-77. PMID 15473966 DOI: 10.1016/J.Neuron.2004.09.030 |
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| 2004 |
Moy LY, Tsai LH. Cyclin-dependent kinase 5 phosphorylates serine 31 of tyrosine hydroxylase and regulates its stability. The Journal of Biological Chemistry. 279: 54487-93. PMID 15471880 DOI: 10.1074/jbc.M406636200 |
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| 2004 |
Cruz JC, Tsai LH. Cdk5 deregulation in the pathogenesis of Alzheimer's disease. Trends in Molecular Medicine. 10: 452-8. PMID 15350898 DOI: 10.1016/j.molmed.2004.07.001 |
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| 2004 |
Nguyen MD, Shu T, Sanada K, Larivière RC, Tseng HC, Park SK, Julien JP, Tsai LH. A NUDEL-dependent mechanism of neurofilament assembly regulates the integrity of CNS neurons. Nature Cell Biology. 6: 595-608. PMID 15208636 DOI: 10.1038/Ncb1139 |
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| 2004 |
Cruz JC, Tsai LH. A Jekyll and Hyde kinase: roles for Cdk5 in brain development and disease. Current Opinion in Neurobiology. 14: 390-4. PMID 15194121 DOI: 10.1016/j.conb.2004.05.002 |
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| 2004 |
Sanada K, Gupta A, Tsai LH. Disabled-1-regulated adhesion of migrating neurons to radial glial fiber contributes to neuronal positioning during early corticogenesis. Neuron. 42: 197-211. PMID 15091337 DOI: 10.1016/S0896-6273(04)00222-3 |
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| 2004 |
Tsai LH, Lee MS, Cruz J. Cdk5, a therapeutic target for Alzheimer's disease? Biochimica Et Biophysica Acta. 1697: 137-42. PMID 15023356 DOI: 10.1016/J.Bbapap.2003.11.019 |
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| 2004 |
Beffert U, Weeber EJ, Morfini G, Ko J, Brady ST, Tsai LH, Sweatt JD, Herz J. Reelin and cyclin-dependent kinase 5-dependent signals cooperate in regulating neuronal migration and synaptic transmission. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 1897-906. PMID 14985430 DOI: 10.1523/Jneurosci.4084-03.2004 |
0.615 |
|
| 2004 |
Morabito MA, Sheng M, Tsai LH. Cyclin-dependent kinase 5 phosphorylates the N-terminal domain of the postsynaptic density protein PSD-95 in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 865-76. PMID 14749431 DOI: 10.1523/JNEUROSCI.4582-03.2004 |
0.363 |
|
| 2004 |
Hammond V, Tsai LH, Tan SS. Control of cortical neuron migration and layering: cell and non cell-autonomous effects of p35. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 576-87. PMID 14724258 DOI: 10.1523/JNEUROSCI.4529-03.2004 |
0.392 |
|
| 2004 |
Xie Z, Tsai LH. Cdk5 phosphorylation of FAK regulates centrosome-associated miocrotubules and neuronal migration. Cell Cycle (Georgetown, Tex.). 3: 108-10. PMID 14712065 DOI: 10.4161/Cc.3.2.646 |
0.417 |
|
| 2004 |
Kao SC, Krichevsky AM, Kosik KS, Tsai LH. BACE1 suppression by RNA interference in primary cortical neurons. The Journal of Biological Chemistry. 279: 1942-9. PMID 14600149 DOI: 10.1074/jbc.M309219200 |
0.317 |
|
| 2004 |
Gupta A, Tsai L. Molecular Mechanisms Underlying Migration and Positioning of Neurons in the Developing Neocortex Microscopy and Microanalysis. 10: 1462-1463. DOI: 10.1017/S1431927604882606 |
0.547 |
|
| 2004 |
Cruz JC, Tsai L. P2-092 Aberrant activation of CDK5 triggers events leading to Alzheimer's pathology Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80839-X |
0.318 |
|
| 2003 |
Gupta A, Tsai LH. Cyclin-dependent kinase 5 and neuronal migration in the neocortex. Neuro-Signals. 12: 173-9. PMID 14673203 DOI: 10.1159/000074618 |
0.559 |
|
| 2003 |
Cruz JC, Tseng HC, Goldman JA, Shih H, Tsai LH. Aberrant Cdk5 activation by p25 triggers pathological events leading to neurodegeneration and neurofibrillary tangles. Neuron. 40: 471-83. PMID 14642273 DOI: 10.1016/S0896-6273(03)00627-5 |
0.392 |
|
| 2003 |
Gupta A, Sanada K, Miyamoto DT, Rovelstad S, Nadarajah B, Pearlman AL, Brunstrom J, Tsai LH. Layering defect in p35 deficiency is linked to improper neuronal-glial interaction in radial migration. Nature Neuroscience. 6: 1284-91. PMID 14608361 DOI: 10.1038/Nn1151 |
0.585 |
|
| 2003 |
Xie Z, Sanada K, Samuels BA, Shih H, Tsai LH. Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration. Cell. 114: 469-82. PMID 12941275 DOI: 10.1016/S0092-8674(03)00605-6 |
0.696 |
|
| 2003 |
Samuels BA, Tsai LH. Cdk5 is a dynamo at the synapse. Nature Cell Biology. 5: 689-90. PMID 12894171 DOI: 10.1038/ncb0803-689 |
0.681 |
|
| 2003 |
Lee MS, Tsai LH. Cdk5: one of the links between senile plaques and neurofibrillary tangles? Journal of Alzheimer's Disease : Jad. 5: 127-37. PMID 12719630 DOI: 10.3233/Jad-2003-5207 |
0.35 |
|
| 2003 |
Patzke H, Maddineni U, Ayala R, Morabito M, Volker J, Dikkes P, Ahlijanian MK, Tsai LH. Partial rescue of the p35-/- brain phenotype by low expression of a neuronal-specific enolase p25 transgene. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 2769-78. PMID 12684463 DOI: 10.1523/JNEUROSCI.23-07-02769.2003 |
0.36 |
|
| 2002 |
Dhavan R, Greer PL, Morabito MA, Orlando LR, Tsai LH. The cyclin-dependent kinase 5 activators p35 and p39 interact with the alpha-subunit of Ca2+/calmodulin-dependent protein kinase II and alpha-actinin-1 in a calcium-dependent manner. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 7879-91. PMID 12223541 |
0.8 |
|
| 2002 |
Augustinack JC, Sanders JL, Tsai LH, Hyman BT. Colocalization and fluorescence resonance energy transfer between cdk5 and AT8 suggests a close association in pre-neurofibrillary tangles and neurofibrillary tangles. Journal of Neuropathology and Experimental Neurology. 61: 557-64. PMID 12071639 DOI: 10.1093/Jnen/61.6.557 |
0.356 |
|
| 2002 |
Gupta A, Tsai LH, Wynshaw-Boris A. Life is a journey: a genetic look at neocortical development. Nature Reviews. Genetics. 3: 342-55. PMID 11988760 DOI: 10.1038/Nrg799 |
0.465 |
|
| 2002 |
Smith DS, Tsai LH. Cdk5 behind the wheel: a role in trafficking and transport? Trends in Cell Biology. 12: 28-36. PMID 11854007 DOI: 10.1016/S0962-8924(01)02181-X |
0.484 |
|
| 2002 |
Patzke H, Tsai LH. Calpain-mediated cleavage of the cyclin-dependent kinase-5 activator p39 to p29. The Journal of Biological Chemistry. 277: 8054-60. PMID 11784720 DOI: 10.1074/jbc.M109645200 |
0.357 |
|
| 2002 |
Ross S, Tienhaara A, Lee MS, Tsai LH, Gill G. GC box-binding transcription factors control the neuronal specific transcription of the cyclin-dependent kinase 5 regulator p35. The Journal of Biological Chemistry. 277: 4455-64. PMID 11724806 DOI: 10.1074/Jbc.M110771200 |
0.4 |
|
| 2002 |
Dhavan R, Greer PL, Morabito MA, Orlando LR, Tsai L. The Cyclin-Dependent Kinase 5 Activators p35 and p39 Interact with the α-Subunit of Ca2+/Calmodulin-Dependent Protein Kinase II and α-Actinin-1 in a Calcium-Dependent Manner The Journal of Neuroscience. 22: 7879-7891. DOI: 10.1523/Jneurosci.22-18-07879.2002 |
0.803 |
|
| 2001 |
Dhavan R, Tsai LH. A decade of CDK5. Nature Reviews. Molecular Cell Biology. 2: 749-59. PMID 11584302 DOI: 10.1038/35096019 |
0.809 |
|
| 2001 |
Tarricone C, Dhavan R, Peng J, Areces LB, Tsai LH, Musacchio A. Structure and regulation of the CDK5-p25(nck5a) complex. Molecular Cell. 8: 657-69. PMID 11583627 DOI: 10.1016/S1097-2765(01)00343-4 |
0.79 |
|
| 2001 |
Ko J, Humbert S, Bronson RT, Takahashi S, Kulkarni AB, Li E, Tsai LH. p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6758-71. PMID 11517264 DOI: 10.1523/Jneurosci.21-17-06758.2001 |
0.608 |
|
| 2001 |
Patrick GN, Zukerberg L, Nikolic M, de La Monte S, Dikkes P, Tsai LH. reply: Neurobiologyp25 protein in neurodegeneration. Nature. 411: 764-765. PMID 11460109 DOI: 10.1038/35081149 |
0.605 |
|
| 2001 |
Patrick GN, Zukerberg L, Nikolic M, De La Monte S, Dikkes P, Tsai LH. P25 protein in neurodegeneration Nature. 411: 763-765. PMID 11459045 |
0.571 |
|
| 2001 |
Smith DS, Greer PL, Tsai LH. Cdk5 on the brain. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 12: 277-83. PMID 11432802 |
0.507 |
|
| 2001 |
Gupta A, Tsai LH. Neuroscience. A kinase to dampen the effects of cocaine? Science (New York, N.Y.). 292: 236-7. PMID 11305318 |
0.414 |
|
| 2001 |
Lee MS, Tsai LH. Cdk5 at the junction. Nature Neuroscience. 4: 340-2. PMID 11276216 DOI: 10.1038/85967 |
0.319 |
|
| 2001 |
Floyd SR, Porro EB, Slepnev VI, Ochoa GC, Tsai LH, De Camilli P. Amphiphysin 1 binds the cyclin-dependent kinase (cdk) 5 regulatory subunit p35 and is phosphorylated by cdk5 and cdc2. The Journal of Biological Chemistry. 276: 8104-10. PMID 11113134 DOI: 10.1074/Jbc.M008932200 |
0.805 |
|
| 2001 |
Gupta A, Tsai L. A Kinase to Dampen the Effects of Cocaine Science. 292: 236-237. DOI: 10.1126/Science.292.5515.236 |
0.504 |
|
| 2000 |
Niethammer M, Smith DS, Ayala R, Peng J, Ko J, Lee MS, Morabito M, Tsai LH. NUDEL is a novel Cdk5 substrate that associates with LIS1 and cytoplasmic dynein. Neuron. 28: 697-711. PMID 11163260 DOI: 10.1016/S0896-6273(00)00147-1 |
0.708 |
|
| 2000 |
Smith DS, Niethammer M, Ayala R, Zhou Y, Gambello MJ, Wynshaw-Boris A, Tsai LH. Regulation of cytoplasmic dynein behaviour and microtubule organization by mammalian Lis1. Nature Cell Biology. 2: 767-75. PMID 11056530 DOI: 10.1038/35041000 |
0.462 |
|
| 2000 |
Nikolic M, Tsai LH. Activity and regulation of p35/Cdk5 kinase complex. Methods in Enzymology. 325: 200-13. PMID 11036605 DOI: 10.1016/S0076-6879(00)25444-X |
0.39 |
|
| 2000 |
Zukerberg LR, Patrick GN, Nikolic M, Humbert S, Wu CL, Lanier LM, Gertler FB, Vidal M, Van Etten RA, Tsai LH. Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth. Neuron. 26: 633-46. PMID 10896159 DOI: 10.1016/S0896-6273(00)81200-3 |
0.701 |
|
| 2000 |
Lee MS, Kwon YT, Li M, Peng J, Friedlander RM, Tsai LH. Neurotoxicity induces cleavage of p35 to p25 by calpain. Nature. 405: 360-4. PMID 10830966 DOI: 10.1038/35012636 |
0.362 |
|
| 2000 |
Kwon YT, Gupta A, Zhou Y, Nikolic M, Tsai LH. Regulation of N-cadherin-mediated adhesion by the p35-Cdk5 kinase. Current Biology : Cb. 10: 363-72. PMID 10753743 DOI: 10.1016/S0960-9822(00)00411-5 |
0.594 |
|
| 1999 |
Bibb JA, Snyder GL, Nishi A, Yan Z, Meijer L, Fienberg AA, Tsai LH, Kwon YT, Girault JA, Czernik AJ, Huganir RL, Hemmings HC, Nairn AC, Greengard P. Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons. Nature. 402: 669-71. PMID 10604473 DOI: 10.1038/45251 |
0.353 |
|
| 1999 |
Patrick GN, Zukerberg L, Nikolic M, de la Monte S, Dikkes P, Tsai LH. Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration. Nature. 402: 615-22. PMID 10604467 DOI: 10.1038/45159 |
0.677 |
|
| 1999 |
Huang D, Patrick G, Moffat J, Tsai LH, Andrews B. Mammalian Cdk5 is a functional homologue of the budding yeast Pho85 cyclin-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America. 96: 14445-50. PMID 10588725 DOI: 10.1073/Pnas.96.25.14445 |
0.687 |
|
| 1998 |
Nikolic M, Chou MM, Lu W, Mayer BJ, Tsai LH. The p35/Cdk5 kinase is a neuron-specific Rac effector that inhibits Pak1 activity. Nature. 395: 194-8. PMID 9744280 DOI: 10.1038/26034 |
0.403 |
|
| 1998 |
Patrick GN, Zhou P, Kwon YT, Howley PM, Tsai LH. p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway. The Journal of Biological Chemistry. 273: 24057-64. PMID 9727024 DOI: 10.1074/Jbc.273.37.24057 |
0.679 |
|
| 1998 |
Kwon YT, Tsai LH. A novel disruption of cortical development in p35(-/-) mice distinct from reeler. The Journal of Comparative Neurology. 395: 510-22. PMID 9619503 DOI: 10.1002/(SICI)1096-9861(19980615)395:4<510::AID-CNE7>3.0.CO;2-4 |
0.373 |
|
| 1997 |
Philpott A, Porro EB, Kirschner MW, Tsai LH. The role of cyclin-dependent kinase 5 and a novel regulatory subunit in regulating muscle differentiation and patterning. Genes & Development. 11: 1409-21. PMID 9192869 DOI: 10.1101/Gad.11.11.1409 |
0.798 |
|
| 1997 |
Delalle I, Bhide PG, Caviness VS, Tsai LH. Temporal and spatial patterns of expression of p35, a regulatory subunit of cyclin-dependent kinase 5, in the nervous system of the mouse. Journal of Neurocytology. 26: 283-96. PMID 9192293 DOI: 10.1023/A:1018500617374 |
0.401 |
|
| 1997 |
Chae T, Kwon YT, Bronson R, Dikkes P, Li E, Tsai LH. Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality. Neuron. 18: 29-42. PMID 9010203 DOI: 10.1016/S0896-6273(01)80044-1 |
0.381 |
|
| 1996 |
Nikolic M, Dudek H, Kwon YT, Ramos YF, Tsai LH. The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation. Genes & Development. 10: 816-25. PMID 8846918 DOI: 10.1101/Gad.10.7.816 |
0.419 |
|
| 1996 |
Guidato S, Tsai LH, Woodgett J, Miller CC. Differential cellular phosphorylation of neurofilament heavy side-arms by glycogen synthase kinase-3 and cyclin-dependent kinase-5. Journal of Neurochemistry. 66: 1698-706. PMID 8627328 DOI: 10.1046/J.1471-4159.1996.66041698.X |
0.311 |
|
| 1995 |
Harper JW, Elledge SJ, Keyomarsi K, Dynlacht B, Tsai LH, Zhang P, Dobrowolski S, Bai C, Connell-Crowley L, Swindell E. Inhibition of cyclin-dependent kinases by p21. Molecular Biology of the Cell. 6: 387-400. PMID 7626805 DOI: 10.1091/Mbc.6.4.387 |
0.577 |
|
| 1994 |
Tsai LH, Delalle I, Caviness VS, Chae T, Harlow E. p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5. Nature. 371: 419-23. PMID 8090221 DOI: 10.1038/371419A0 |
0.6 |
|
| 1993 |
Tsai LH, Lees E, Faha B, Harlow E, Riabowol K. The cdk2 kinase is required for the G1-to-S transition in mammalian cells. Oncogene. 8: 1593-602. PMID 8502482 |
0.495 |
|
| 1993 |
Tsai LH, Takahashi T, Caviness VS, Harlow E. Activity and expression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system. Development (Cambridge, England). 119: 1029-40. PMID 8306873 |
0.56 |
|
| 1992 |
Meyerson M, Enders GH, Wu CL, Su LK, Gorka C, Nelson C, Harlow E, Tsai LH. A family of human cdc2-related protein kinases. The Embo Journal. 11: 2909-17. PMID 1639063 DOI: 10.1002/J.1460-2075.1992.Tb05360.X |
0.575 |
|
| 1992 |
Faha B, Ewen ME, Tsai LH, Livingston DM, Harlow E. Interaction between human cyclin A and adenovirus E1A-associated p107 protein. Science (New York, N.Y.). 255: 87-90. PMID 1532458 DOI: 10.1126/Science.1532458 |
0.575 |
|
| 1992 |
Cao L, Faha B, Dembski M, Tsai LH, Harlow E, Dyson N. Independent binding of the retinoblastoma protein and p107 to the transcription factor E2F. Nature. 355: 176-9. PMID 1530885 DOI: 10.1038/355176A0 |
0.689 |
|
| 1992 |
Meyerson M, Enders G, Wu C, Su L, Gorka C, Nelson C, Harlow E, Tsai L. A family of human cdc2-related protein kinases. The Embo Journal. 11: 2909-2917. DOI: 10.1002/j.1460-2075.1992.tb05360.x |
0.463 |
|
| 1991 |
Meyerson M, Faha B, Su LK, Harlow E, Tsai LH. The cyclin-dependent kinase family. Cold Spring Harbor Symposia On Quantitative Biology. 56: 177-86. PMID 1840251 DOI: 10.1101/Sqb.1991.056.01.023 |
0.465 |
|
| 1991 |
Tsai LH, Harlow E, Meyerson M. Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase. Nature. 353: 174-7. PMID 1653904 DOI: 10.1038/353174A0 |
0.577 |
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