| Year |
Citation |
Score |
| 2024 |
Crocetti L, Guerrini G, Melani F, Mascia MP, Giovannoni MP. 3,8-Disubstituted Pyrazolo[1,5-a]quinazoline as GABA Receptor Modulators: Synthesis, Electrophysiological Assays, and Molecular Modelling Studies. International Journal of Molecular Sciences. 25. PMID 39409169 DOI: 10.3390/ijms251910840 |
0.367 |
|
| 2022 |
Crocetti L, Guerrini G, Melani F, Vergelli C, Mascia MP, Giovannoni MP. GABA Receptor Modulators with a Pyrazolo[1,5-a]quinazoline Core: Synthesis, Molecular Modelling Studies and Electrophysiological Assays. International Journal of Molecular Sciences. 23. PMID 36361842 DOI: 10.3390/ijms232113032 |
0.395 |
|
| 2021 |
Crocetti L, Guerrini G, Cantini N, Vergelli C, Melani F, Mascia MP, Giovannoni MP. 'Proximity frequencies' a new parameter to evaluate the profile of GABAR modulators. Bioorganic & Medicinal Chemistry Letters. 34: 127755. PMID 33359444 DOI: 10.1016/j.bmcl.2020.127755 |
0.347 |
|
| 2019 |
Guerrini G, Vergelli C, Cantini N, Giovannoni MP, Daniele S, Mascia MP, Martini C, Crocetti L. Synthesis of New GABAA Receptor Modulator with Pyrazolo[1,5-a]quinazoline (PQ) Scaffold. International Journal of Molecular Sciences. 20: 1438. PMID 30901916 DOI: 10.3390/Ijms20061438 |
0.427 |
|
| 2016 |
Cappelli A, Anzini M, Castriconi F, Grisci G, Paolino M, Braile C, Valenti S, Giuliani G, Vomero S, Di Capua A, Betti L, Giannaccini G, Lucacchini A, Ghelardini C, Di Cesare Mannelli L, ... ... Mascia MP, et al. Design, Synthesis, and Biological Evaluation of Imidazo[1,5-a]quinoline as Highly Potent Ligands of Central Benzodiazepine Receptors. Journal of Medicinal Chemistry. PMID 26982523 DOI: 10.1021/Acs.Jmedchem.6B00034 |
0.384 |
|
| 2014 |
Mascia MP, Ledda G, Orrù A, Marongiu A, Loriga G, Maciocco E, Biggio G, Ruiu S. Differential modulation of GABA(A) receptor function by aryl pyrazoles. European Journal of Pharmacology. 733: 1-6. PMID 24704372 DOI: 10.1016/J.Ejphar.2014.03.039 |
0.484 |
|
| 2011 |
Anzini M, Valenti S, Braile C, Cappelli A, Vomero S, Alcaro S, Ortuso F, Marinelli L, Limongelli V, Novellino E, Betti L, Giannaccini G, Lucacchini A, Daniele S, Martini C, ... ... Mascia MP, et al. New insight into the central benzodiazepine receptor-ligand interactions: design, synthesis, biological evaluation, and molecular modeling of 3-substituted 6-phenyl-4H-imidazo[1,5-a][1,4]benzodiazepines and related compounds. Journal of Medicinal Chemistry. 54: 5694-711. PMID 21751815 DOI: 10.1021/Jm2001597 |
0.406 |
|
| 2011 |
Sanna E, Talani G, Obili N, Mascia MP, Mostallino MC, Secci PP, Pisu MG, Biggio F, Utzeri C, Olla P, Biggio G, Follesa P. Voluntary Ethanol Consumption Induced by Social Isolation Reverses the Increase of α(4)/δ GABA(A) Receptor Gene Expression and Function in the Hippocampus of C57BL/6J Mice. Frontiers in Neuroscience. 5: 15. PMID 21347217 DOI: 10.3389/Fnins.2011.00015 |
0.598 |
|
| 2007 |
Mascia MP, Bachis E, Obili N, Maciocco E, Cocco GA, Sechi GP, Biggio G. Thiocolchicoside inhibits the activity of various subtypes of recombinant GABA(A) receptors expressed in Xenopus laevis oocytes. European Journal of Pharmacology. 558: 37-42. PMID 17234181 DOI: 10.1016/J.Ejphar.2006.11.076 |
0.568 |
|
| 2005 |
Mascia MP, Asproni B, Busonero F, Talani G, Maciocco E, Pau A, Cerri R, Sanna E, Biggio G. Ethyl 2-(4-bromophenyl)-1-(2,4-dichlorophenyl)-1H-4-imidazolecarboxylate is a novel positive modulator of GABAA receptors. European Journal of Pharmacology. 516: 204-11. PMID 15967425 DOI: 10.1016/J.Ejphar.2005.05.006 |
0.677 |
|
| 2005 |
Ferlin MG, Chiarelotto G, Dall'Acqua S, Maciocco E, Mascia MP, Pisu MG, Biggio G. Novel anellated pyrazoloquinolin-3-ones: synthesis and in vitro BZR activity. Bioorganic & Medicinal Chemistry. 13: 3531-41. PMID 15848766 DOI: 10.1016/J.Bmc.2005.02.042 |
0.366 |
|
| 2005 |
Asproni B, Talani G, Busonero F, Pau A, Sanna S, Cerri R, Mascia MP, Sanna E, Biggio G. Synthesis, structure-activity relationships at the GABA(A) receptor in rat brain, and differential electrophysiological profile at the recombinant human GABA(A) receptor of a series of substituted 1,2-diphenylimidazoles. Journal of Medicinal Chemistry. 48: 2638-45. PMID 15801854 DOI: 10.1021/Jm049120Y |
0.655 |
|
| 2004 |
Mostallino MC, Mascia MP, Pisu MG, Busonero F, Talani G, Biggio G. Inhibition by miltirone of up-regulation of GABAA receptor alpha4 subunit mRNA by ethanol withdrawal in hippocampal neurons. European Journal of Pharmacology. 494: 83-90. PMID 15212961 DOI: 10.1016/J.Ejphar.2004.04.021 |
0.588 |
|
| 2004 |
Lobo IA, Mascia MP, Trudell JR, Harris RA. Channel gating of the glycine receptor changes accessibility to residues implicated in receptor potentiation by alcohols and anesthetics. The Journal of Biological Chemistry. 279: 33919-27. PMID 15169788 DOI: 10.1074/Jbc.M313941200 |
0.761 |
|
| 2003 |
Carotti A, Altomare C, Savini L, Chiasserini L, Pellerano C, Mascia MP, Maciocco E, Busonero F, Mameli M, Biggio G, Sanna E. High affinity central benzodiazepine receptor ligands. Part 3: insights into the pharmacophore and pattern recognition study of intrinsic activities of pyrazolo[4,3-c]quinolin-3-ones. Bioorganic & Medicinal Chemistry. 11: 5259-72. PMID 14604690 DOI: 10.1016/S0968-0896(03)00527-3 |
0.642 |
|
| 2003 |
Follesa P, Mancuso L, Biggio F, Mostallino MC, Manca A, Mascia MP, Busonero F, Talani G, Sanna E, Biggio G. Gamma-hydroxybutyric acid and diazepam antagonize a rapid increase in GABA(A) receptors alpha(4) subunit mRNA abundance induced by ethanol withdrawal in cerebellar granule cells. Molecular Pharmacology. 63: 896-907. PMID 12644591 DOI: 10.1124/Mol.63.4.896 |
0.679 |
|
| 2003 |
Campagna F, Palluotto F, Mascia MP, Maciocco E, Marra C, Carotti A, Carrieri A. Synthesis and biological evaluation of pyridazino[4,3-b]indoles and indeno[1,2-c]pyridazines as new ligands of central and peripheral benzodiazepine receptors. Farmaco (Societã Chimica Italiana : 1989). 58: 129-40. PMID 12581779 DOI: 10.1016/S0014-827X(02)00017-4 |
0.336 |
|
| 2002 |
Mascia MP, Biggio F, Mancuso L, Cabras S, Cocco PL, Gorini G, Manca A, Marra C, Purdy RH, Follesa P, Biggio G. Changes in GABA(A) receptor gene expression induced by withdrawal of, but not by long-term exposure to, ganaxolone in cultured rat cerebellar granule cells. The Journal of Pharmacology and Experimental Therapeutics. 303: 1014-20. PMID 12438522 DOI: 10.1124/Jpet.102.040063 |
0.655 |
|
| 2002 |
Findlay GS, Wick MJ, Mascia MP, Wallace D, Miller GW, Harris RA, Blednov YA. Transgenic expression of a mutant glycine receptor decreases alcohol sensitivity of mice. The Journal of Pharmacology and Experimental Therapeutics. 300: 526-34. PMID 11805213 DOI: 10.1124/Jpet.300.2.526 |
0.585 |
|
| 2001 |
Mascia MP, Maiya R, Borghese CM, Lobo IA, Hara K, Yamakura T, Gong DH, Beckstead MJ. Does acetaldehyde mediate ethanol action in the central nervous system? Alcoholism, Clinical and Experimental Research. 25: 1570-5. PMID 11707631 DOI: 10.1111/J.1530-0277.2001.Tb02163.X |
0.736 |
|
| 2001 |
Ueno S, Harris RA, Messing RO, Sanchez-Perez AM, Hodge CW, McMahon T, Wang D, Mehmert KK, Kelley SP, Haywood A, Olive MF, Buck KJ, Hood HM, Blednov Y, Findlay G, ... Mascia MP, et al. Alcohol actions on GABA(A) receptors: from protein structure to mouse behavior. Alcoholism, Clinical and Experimental Research. 25: 76S-81S. PMID 11391054 DOI: 10.1111/J.1530-0277.2001.Tb02378.X |
0.597 |
|
| 2000 |
Zhang Y, Trudell JR, Mascia MP, Laster MJ, Gong DH, Harris RA, Eger EI. The anesthetic potencies of alkanethiols for rats: relevance to theories of narcosis. Anesthesia and Analgesia. 91: 1294-9. PMID 11049925 DOI: 10.1213/00000539-200011000-00045 |
0.35 |
|
| 2000 |
Mascia MP, Gong DH, Eger EI, Harris RA. The anesthetic potency of propanol and butanol versus propanethiol and butanethiol in alpha1 wild type and alpha1(S267Q) glycine receptors. Anesthesia and Analgesia. 91: 1289-93. PMID 11049924 |
0.555 |
|
| 2000 |
Wick MJ, Radcliffe RA, Bowers BJ, Mascia MP, Lüscher B, Harris RA, Wehner JM. Behavioural changes produced by transgenic overexpression of gamma2L and gamma2S subunits of the GABAA receptor. The European Journal of Neuroscience. 12: 2634-8. PMID 10947837 DOI: 10.1046/J.1460-9568.2000.00160.X |
0.567 |
|
| 2000 |
Mascia MP, Trudell JR, Harris RA. Specific binding sites for alcohols and anesthetics on ligand-gated ion channels. Proceedings of the National Academy of Sciences of the United States of America. 97: 9305-10. PMID 10908659 DOI: 10.1073/Pnas.160128797 |
0.597 |
|
| 2000 |
Mascia MP, Gong DH, Eger EI, Harris RA. The Anesthetic Potency of Propanol and Butanol Versus Propanethiol and Butanethiol in α1 Wild Type and α1(s267q) Glycine Receptors Anesthesia & Analgesia. 91: 1289-1293. DOI: 10.1213/00000539-200011000-00044 |
0.614 |
|
| 1998 |
Mascia MP, Wick MJ, Martinez LD, Harris RA. Enhancement of glycine receptor function by ethanol: role of phosphorylation. British Journal of Pharmacology. 125: 263-70. PMID 9786497 DOI: 10.1038/Sj.Bjp.0702054 |
0.616 |
|
| 1998 |
Wick MJ, Mihic SJ, Ueno S, Mascia MP, Trudell JR, Brozowski SJ, Ye Q, Harrison NL, Harris RA. Mutations of gamma-aminobutyric acid and glycine receptors change alcohol cutoff: evidence for an alcohol receptor? Proceedings of the National Academy of Sciences of the United States of America. 95: 6504-9. PMID 9600996 DOI: 10.1073/Pnas.95.11.6504 |
0.708 |
|
| 1998 |
Ye Q, Koltchine VV, Mihic SJ, Mascia MP, Wick MJ, Finn SE, Harrison NL, Harris RA. Enhancement of glycine receptor function by ethanol is inversely correlated with molecular volume at position alpha267. The Journal of Biological Chemistry. 273: 3314-9. PMID 9452448 DOI: 10.1074/Jbc.273.6.3314 |
0.757 |
|
| 1997 |
Mihic SJ, Ye Q, Wick MJ, Koltchine VV, Krasowski MD, Finn SE, Mascia MP, Valenzuela CF, Hanson KK, Greenblatt EP, Harris RA, Harrison NL. Sites of alcohol and volatile anaesthetic action on GABA(A) and glycine receptors. Nature. 389: 385-9. PMID 9311780 DOI: 10.1038/38738 |
0.759 |
|
| 1997 |
Mascia MP, Bleck VG, Harris RA. Glycine receptors from long-sleep and short-sleep mice: genetic differences in drug sensitivity. Brain Research. Molecular Brain Research. 45: 169-72. PMID 9105687 DOI: 10.1016/S0169-328X(97)00008-9 |
0.51 |
|
| 1996 |
Mascia MP, Machu TK, Harris RA. Enhancement of homomeric glycine receptor function by long-chain alcohols and anaesthetics. British Journal of Pharmacology. 119: 1331-6. PMID 8968539 DOI: 10.1111/j.1476-5381.1996.tb16042.x |
0.544 |
|
| 1996 |
Concas A, Mascia MP, Cuccheddu T, Floris S, Mostallino MC, Perra C, Satta S, Biggio G. Chronic ethanol intoxication enhances [3H]CCPA binding and does not reduce A1 adenosine receptor function in rat cerebellum. Pharmacology, Biochemistry, and Behavior. 53: 249-55. PMID 8808128 DOI: 10.1016/0091-3057(95)00208-1 |
0.418 |
|
| 1996 |
Mascia MP, Mihic SJ, Valenzuela CF, Schofield PR, Harris RA. A single amino acid determines differences in ethanol actions on strychnine-sensitive glycine receptors. Molecular Pharmacology. 50: 402-6. PMID 8700149 |
0.72 |
|
| 1995 |
Klein RL, Mascia MP, Whiting PJ, Harris RA. GABAA receptor function and binding in stably transfected cells: chronic ethanol treatment. Alcoholism, Clinical and Experimental Research. 19: 1338-44. PMID 8561312 DOI: 10.1111/J.1530-0277.1995.Tb01622.X |
0.641 |
|
| 1995 |
Harris RA, Proctor WR, McQuilkin SJ, Klein RL, Mascia MP, Whatley V, Whiting PJ, Dunwiddie TV. Ethanol increases GABAA responses in cells stably transfected with receptor subunits. Alcoholism, Clinical and Experimental Research. 19: 226-32. PMID 7771653 DOI: 10.1111/J.1530-0277.1995.Tb01496.X |
0.625 |
|
| 1995 |
Sanna E, Mascia MP, Klein RL, Whiting PJ, Biggio G, Harris RA. Actions of the general anesthetic propofol on recombinant human GABAA receptors: influence of receptor subunits. The Journal of Pharmacology and Experimental Therapeutics. 274: 353-60. PMID 7616420 |
0.712 |
|
| 1995 |
Klein RL, Mascia MP, Harkness PC, Hadingham KL, Whiting PJ, Harris RA. Regulation of allosteric coupling and function of stably expressed gamma-aminobutyric acid (GABA)A receptors by chronic treatment with GABAA and benzodiazepine agonists. The Journal of Pharmacology and Experimental Therapeutics. 274: 1484-92. PMID 7562525 |
0.577 |
|
| 1995 |
Mascia MP, Klein RL, Whiting PJ, Harris RA. Regulation of allosteric binding and function of stably expressed GABAA receptors by chronic treatment with ethanol. GABAA and benzodiazcpine agonists Behavioural Pharmacology. 6: 108. DOI: 10.1097/00008877-199505001-00127 |
0.396 |
|
| 1994 |
Concas A, Santoro G, Mascia MP, Maciocco E, Dazzi L, Biggio G. Effects of propofol, pentobarbital and alphaxalone on t-[35S]butylbicyclophosphorothionate binding in rat cerebral cortex. European Journal of Pharmacology. 267: 207-13. PMID 8050480 DOI: 10.1016/0922-4106(94)90172-4 |
0.41 |
|
| 1994 |
Concas A, Cuccheddu T, Floris S, Mascia MP, Biggio G. 2-Chloro-N6-cyclopentyladenosine (CCPA), an adenosine A1 receptor agonist, suppresses ethanol withdrawal syndrome in rats. Alcohol and Alcoholism (Oxford, Oxfordshire). 29: 261-4. PMID 7945566 |
0.301 |
|
| 1994 |
Concas A, Cuccheddu T, Floris S, Mascia MP, Biggio G. 2-Chloro-N6-cyclopentyladenosine (CCPA), an adenosine A1 receptor agonist, suppresses ethanol withdrawal syndrome in rats. Alcohol and Alcoholism. 29: 261-264. DOI: 10.1093/Oxfordjournals.Alcalc.A045532 |
0.415 |
|
| 1994 |
Concas A, Mascia MP, Santoro G, Maciocco E, Pinna G, Sanna E, Biggio G. Failure of GABAergic drugs to modulate [3H]propofol binding in rat brain Neuroscience Research Communications. 15: 21-29. |
0.481 |
|
| 1993 |
Concas A, Santoro G, Mascia MP, Maciocco E, Dazzi L, Ongini E, Biggio G. Anticonvulsant doses of 2-chloro-N6-cyclopentyladenosine, an adenosine A1 receptor agonist, reduce GABAergic transmission in different areas of the mouse brain. The Journal of Pharmacology and Experimental Therapeutics. 267: 844-51. PMID 8246158 |
0.428 |
|
| 1993 |
Concas A, Sanna E, Cuccheddu T, Mascia MP, Santoro G, Maciocco E, Biggio G. Carbon dioxide inhalation, stress and anxiogenic drugs reduce the function of GABAA receptor complex in the rat brain. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 17: 651-61. PMID 7689736 DOI: 10.1016/0278-5846(93)90012-H |
0.558 |
|
| 1992 |
Concas A, Serra M, Sanna E, Pepitoni S, Mascia MP, Biggio G. Involvement of GABA-dependent chloride channel in the action of anticonvulsant and convulsant drugs. Epilepsy Research. Supplement. 8: 77-85. PMID 1329830 |
0.57 |
|
| 1992 |
Concas A, Santoro G, Mascia MP, Serra M, Sanna E, Biggio G. The action of the general anesthetic propofol on GABAA receptors. Advances in Biochemical Psychopharmacology. 47: 349-63. PMID 1324582 |
0.611 |
|
| 1991 |
Concas A, Mascia MP, Sanna E, Santoro G, Serra M, Biggio G. "In vivo" administration of valproate decreases t-[35S]butylbicyclophosphorothionate binding in the rat brain. Naunyn-Schmiedeberg's Archives of Pharmacology. 343: 296-300. PMID 1650919 DOI: 10.1007/Bf00251129 |
0.542 |
|
| 1990 |
Concas A, Sanna E, Mascia MP, Serra M, Biggio G. Diazepam enhances bicuculline-induced increase of t-[35S]butylbicyclophosphorothionate binding in unwashed membrane preparations from rat cerebral cortex. Neuroscience Letters. 112: 87-91. PMID 2385368 DOI: 10.1016/0304-3940(90)90327-6 |
0.583 |
|
| 1990 |
Concas A, Santoro G, Mascia MP, Serra M, Sanna E, Biggio G. The general anesthetic propofol enhances the function of gamma-aminobutyric acid-coupled chloride channel in the rat cerebral cortex. Journal of Neurochemistry. 55: 2135-8. PMID 2172469 DOI: 10.1111/J.1471-4159.1990.Tb05807.X |
0.599 |
|
| 1990 |
Concas A, Sanna E, Serra M, Mascia MP, Santoro V, Biggio G. "Ex vivo" binding of 35S-TBPS as a tool to study the pharmacology of GABAA receptors. Advances in Biochemical Psychopharmacology. 46: 89-108. PMID 1963271 |
0.599 |
|
| Show low-probability matches. |