Boris Striepen - Publications

Affiliations: 
University of Pennsylvania, Philadelphia, PA, United States 

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Haskins BE, Gullicksrud JA, Wallbank BA, Dumaine JE, Guérin A, Cohn IS, O'Dea KM, Pardy RD, Merolle MI, Shallberg LA, Hunter EN, Byerly JH, Smith EJ, Buenconsejo GY, McLeod BI, ... ... Striepen B, et al. Dendritic cell-mediated responses to secreted Cryptosporidium effectors promote parasite-specific CD8+ T cell responses. Mucosal Immunology. PMID 38508522 DOI: 10.1016/j.mucimm.2024.03.003  0.591
2024 Dos Santos Pacheco N, Tell I Puig A, Guérin A, Martinez M, Maco B, Tosetti N, Delgado-Betancourt E, Lunghi M, Striepen B, Chang YW, Soldati-Favre D. Sustained rhoptry docking and discharge requires Toxoplasma gondii intraconoidal microtubule-associated proteins. Nature Communications. 15: 379. PMID 38191574 DOI: 10.1038/s41467-023-44631-y  0.321
2023 Pardy RD, Walzer KA, Wallbank BA, Byerly JH, O'Dea KM, Cohn IS, Haskins BE, Roncaioli JL, Smith EJ, Buenconsejo GY, Striepen B, Hunter CA. Analysis of intestinal epithelial cell responses to highlights the temporal effects of IFN-γ on parasite restriction. Biorxiv : the Preprint Server For Biology. PMID 38014210 DOI: 10.1101/2023.11.14.567008  0.596
2023 Cohn IS, Wallbank BA, Haskins BE, O'Dea KM, Pardy RD, Shaw S, Merolle MI, Gullicksrud JA, Christian DA, Striepen B, Hunter CA. Intestinal cDC1s provide IL-12 dependent and independent functions required for CD4 T cell-mediated resistance to . Biorxiv : the Preprint Server For Biology. PMID 38014026 DOI: 10.1101/2023.11.11.566669  0.556
2023 Pardy RD, Wallbank BA, Striepen B, Hunter CA. Immunity to Cryptosporidium: insights into principles of enteric responses to infection. Nature Reviews. Immunology. PMID 37697084 DOI: 10.1038/s41577-023-00932-3  0.601
2023 Haskins BE, Gullicksrud JA, Wallbank BA, Dumaine JE, Guérin A, Cohn IS, O'Dea KM, Pardy RD, Merolle MI, Shallberg LA, Hunter EN, Byerly JH, Smith EJ, Buenconsejo GY, McLeod BI, ... ... Striepen B, et al. Dendritic cell-mediated responses to secreted effectors are required for parasite-specific CD8 T cell responses. Biorxiv : the Preprint Server For Biology. PMID 37645924 DOI: 10.1101/2023.08.16.553566  0.589
2023 Guérin A, Strelau KM, Barylyuk K, Wallbank BA, Berry L, Crook OM, Lilley KS, Waller RF, Striepen B. Cryptosporidium uses multiple distinct secretory organelles to interact with and modify its host cell. Cell Host & Microbe. PMID 36958336 DOI: 10.1016/j.chom.2023.03.001  0.439
2023 Tandel J, Walzer KA, Byerly JH, Pinkston B, Beiting DP, Striepen B. Genetic Ablation of a Female-Specific Apetala 2 Transcription Factor Blocks Oocyst Shedding in Cryptosporidium parvum. Mbio. 14: e0326122. PMID 36786597 DOI: 10.1128/mbio.03261-22  0.334
2022 Cohn IS, Henrickson SE, Striepen B, Hunter CA. Immunity to Cryptosporidium: Lessons from Acquired and Primary Immunodeficiencies. Journal of Immunology (Baltimore, Md. : 1950). 209: 2261-2268. PMID 36469846 DOI: 10.4049/jimmunol.2200512  0.596
2022 Sparvoli D, Delabre J, Penarete-Vargas DM, Kumar Mageswaran S, Tsypin LM, Heckendorn J, Theveny L, Maynadier M, Mendonça Cova M, Berry-Sterkers L, Guérin A, Dubremetz JF, Urbach S, Striepen B, Turkewitz AP, et al. An apical membrane complex for triggering rhoptry exocytosis and invasion in Toxoplasma. The Embo Journal. e111158. PMID 36245278 DOI: 10.15252/embj.2022111158  0.369
2022 Gibson AR, Sateriale A, Dumaine JE, Engiles JB, Pardy RD, Gullicksrud JA, O'Dea KM, Doench JG, Beiting DP, Hunter CA, Striepen B. A genetic screen identifies a protective type III interferon response to Cryptosporidium that requires TLR3 dependent recognition. Plos Pathogens. 18: e1010003. PMID 35584177 DOI: 10.1371/journal.ppat.1010003  0.61
2021 Dumaine JE, Sateriale A, Gibson AR, Reddy AG, Gullicksrud JA, Hunter EN, Clark JT, Striepen B. The enteric pathogen exports proteins into the cytosol of the infected host cell. Elife. 10. PMID 34866573 DOI: 10.7554/eLife.70451  0.493
2021 Gullicksrud JA, Sateriale A, Engiles JB, Gibson AR, Shaw S, Hutchins ZA, Martin L, Christian DA, Taylor GA, Yamamoto M, Beiting DP, Striepen B, Hunter CA. Enterocyte-innate lymphoid cell crosstalk drives early IFN-γ-mediated control of Cryptosporidium. Mucosal Immunology. PMID 34750455 DOI: 10.1038/s41385-021-00468-6  0.575
2021 Mageswaran SK, Guérin A, Theveny LM, Chen WD, Martinez M, Lebrun M, Striepen B, Chang YW. In situ ultrastructures of two evolutionarily distant apicomplexan rhoptry secretion systems. Nature Communications. 12: 4983. PMID 34404783 DOI: 10.1038/s41467-021-25309-9  0.464
2021 Guérin A, Roy NH, Kugler EM, Berry L, Burkhardt JK, Shin JB, Striepen B. Cryptosporidium rhoptry effector protein ROP1 injected during invasion targets the host cytoskeletal modulator LMO7. Cell Host & Microbe. PMID 34348092 DOI: 10.1016/j.chom.2021.07.002  0.483
2021 Aquilini E, Cova MM, Mageswaran SK, Dos Santos Pacheco N, Sparvoli D, Penarete-Vargas DM, Najm R, Graindorge A, Suarez C, Maynadier M, Berry-Sterkers L, Urbach S, Fahy PR, Guérin AN, Striepen B, et al. An Alveolata secretory machinery adapted to parasite host cell invasion. Nature Microbiology. PMID 33495622 DOI: 10.1038/s41564-020-00854-z  0.419
2021 Sateriale A, Gullicksrud JA, Engiles JB, McLeod BI, Kugler EM, Henao-Mejia J, Zhou T, Ring AM, Brodsky IE, Hunter CA, Striepen B. The intestinal parasite is controlled by an enterocyte intrinsic inflammasome that depends on NLRP6. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33372132 DOI: 10.1073/pnas.2007807118  0.594
2021 Guérin A, Striepen B. The Biology of the Intestinal Intracellular Parasite Cryptosporidium. Cell Host & Microbe. 28: 509-515. PMID 33031769 DOI: 10.1016/j.chom.2020.09.007  0.4
2020 Vinayak S, Jumani RS, Miller P, Hasan MM, McLeod BI, Tandel J, Stebbins EE, Teixeira JE, Borrel J, Gonse A, Zhang M, Yu X, Wernimont A, Walpole C, Eckley S, ... ... Striepen B, et al. Bicyclic azetidines kill the diarrheal pathogen in mice by inhibiting parasite phenylalanyl-tRNA synthetase. Science Translational Medicine. 12. PMID 32998973 DOI: 10.1126/scitranslmed.aba8412  0.327
2019 Pawlowic MC, Somepalli M, Sateriale A, Herbert GT, Gibson AR, Cuny GD, Hedstrom L, Striepen B. Genetic ablation of purine salvage in reveals nucleotide uptake from the host cell. Proceedings of the National Academy of Sciences of the United States of America. PMID 31570573 DOI: 10.1073/Pnas.1908239116  0.353
2019 Suarez C, Lentini G, Ramaswamy R, Maynadier M, Aquilini E, Berry-Sterkers L, Cipriano M, Chen AL, Bradley P, Striepen B, Boulanger MJ, Lebrun M. A lipid-binding protein mediates rhoptry discharge and invasion in Plasmodium falciparum and Toxoplasma gondii parasites. Nature Communications. 10: 4041. PMID 31492901 DOI: 10.1038/S41467-019-11979-Z  0.396
2019 English ED, Striepen B. The cat is out of the bag: How parasites know their hosts. Plos Biology. 17: e3000446. PMID 31487278 DOI: 10.1371/journal.pbio.3000446  0.368
2019 Tandel J, English ED, Sateriale A, Gullicksrud JA, Beiting DP, Sullivan MC, Pinkston B, Striepen B. Life cycle progression and sexual development of the apicomplexan parasite Cryptosporidium parvum. Nature Microbiology. PMID 31477896 DOI: 10.1038/s41564-019-0539-x  0.419
2019 Sateriale A, Šlapeta J, Baptista R, Engiles JB, Gullicksrud JA, Herbert GT, Brooks CF, Kugler EM, Kissinger JC, Hunter CA, Striepen B. A Genetically Tractable, Natural Mouse Model of Cryptosporidiosis Offers Insights into Host Protective Immunity. Cell Host & Microbe. PMID 31231045 DOI: 10.1016/J.Chom.2019.05.006  0.577
2018 Biddau M, Bouchut A, Major J, Saveria T, Tottey J, Oka O, van-Lith M, Jennings KE, Ovciarikova J, DeRocher A, Striepen B, Waller RF, Parsons M, Sheiner L. Two essential Thioredoxins mediate apicoplast biogenesis, protein import, and gene expression in Toxoplasma gondii. Plos Pathogens. 14: e1006836. PMID 29470517 DOI: 10.1371/Journal.Ppat.1006836  0.315
2017 Pawlowic MC, Vinayak S, Sateriale A, Brooks CF, Striepen B. Generating and Maintaining Transgenic Cryptosporidium parvum Parasites. Current Protocols in Microbiology. 46: 20B.2.1-20B.2.32. PMID 28800157 DOI: 10.1002/cpmc.33  0.345
2017 Manjunatha UH, Vinayak S, Zambriski JA, Chao AT, Sy T, Noble CG, Bonamy GMC, Kondreddi RR, Zou B, Gedeck P, Brooks CF, Herbert GT, Sateriale A, Tandel J, Noh S, ... ... Striepen B, et al. A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis. Nature. PMID 28562588 DOI: 10.1038/Nature22337  0.301
2015 Vinayak S, Pawlowic MC, Sateriale A, Brooks CF, Studstill CJ, Bar-Peled Y, Cipriano MJ, Striepen B. Genetic modification of the diarrhoeal pathogen Cryptosporidium parvum Nature. 523: 477-480. PMID 26176919 DOI: 10.1038/nature14651  0.308
2015 Lentini G, Kong-Hap M, El Hajj H, Francia M, Claudet C, Striepen B, Dubremetz JF, Lebrun M. Identification and characterization of Toxoplasma SIP, a conserved apicomplexan cytoskeleton protein involved in maintaining the shape, motility and virulence of the parasite. Cellular Microbiology. 17: 62-78. PMID 25088010 DOI: 10.1111/cmi.12337  0.336
2014 Francia ME, Striepen B. Cell division in apicomplexan parasites. Nature Reviews. Microbiology. 12: 125-36. PMID 24384598 DOI: 10.1038/nrmicro3184  0.359
2013 Striepen B. Parasitic infections: Time to tackle cryptosporidiosis. Nature. 503: 189-91. PMID 24236315 DOI: 10.1038/503189a  0.395
2013 Li ZH, Ramakrishnan S, Striepen B, Moreno SN. Toxoplasma gondii relies on both host and parasite isoprenoids and can be rendered sensitive to atorvastatin. Plos Pathogens. 9: e1003665. PMID 24146616 DOI: 10.1371/journal.ppat.1003665  0.435
2013 Ramakrishnan S, Serricchio M, Striepen B, Bütikofer P. Lipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexans. Progress in Lipid Research. 52: 488-512. PMID 23827884 DOI: 10.1016/j.plipres.2013.06.003  0.308
2013 van Dooren GG, Striepen B. The algal past and parasite present of the apicoplast. Annual Review of Microbiology. 67: 271-89. PMID 23808340 DOI: 10.1146/annurev-micro-092412-155741  0.466
2013 Coombes JL, Charsar BA, Han SJ, Halkias J, Chan SW, Koshy AA, Striepen B, Robey EA. Motile invaded neutrophils in the small intestine of Toxoplasma gondii-infected mice reveal a potential mechanism for parasite spread. Proceedings of the National Academy of Sciences of the United States of America. 110: E1913-22. PMID 23650399 DOI: 10.1073/pnas.1220272110  0.502
2012 Francia ME, Jordan CN, Patel JD, Sheiner L, Demerly JL, Fellows JD, de Leon JC, Morrissette NS, Dubremetz JF, Striepen B. Cell division in Apicomplexan parasites is organized by a homolog of the striated rootlet fiber of algal flagella. Plos Biology. 10: e1001444. PMID 23239939 DOI: 10.1371/Journal.Pbio.1001444  0.332
2012 MacRae JI, Sheiner L, Nahid A, Tonkin C, Striepen B, McConville MJ. Mitochondrial metabolism of glucose and glutamine is required for intracellular growth of Toxoplasma gondii. Cell Host & Microbe. 12: 682-92. PMID 23159057 DOI: 10.1016/j.chom.2012.09.013  0.342
2012 Sampels V, Hartmann A, Dietrich I, Coppens I, Sheiner L, Striepen B, Herrmann A, Lucius R, Gupta N. Conditional mutagenesis of a novel choline kinase demonstrates plasticity of phosphatidylcholine biogenesis and gene expression in Toxoplasma gondii. The Journal of Biological Chemistry. 287: 16289-99. PMID 22451671 DOI: 10.1074/Jbc.M112.347138  0.336
2012 Striepen B. The apicoplast: a red alga in human parasites. Essays in Biochemistry. 51: 111-25. PMID 22023445 DOI: 10.1042/bse0510111  0.312
2011 Besteiro S, Brooks CF, Striepen B, Dubremetz JF. Autophagy protein Atg3 is essential for maintaining mitochondrial integrity and for normal intracellular development of Toxoplasma gondii tachyzoites. Plos Pathogens. 7: e1002416. PMID 22144900 DOI: 10.1371/journal.ppat.1002416  0.364
2011 Nair SC, Brooks CF, Goodman CD, Sturm A, Strurm A, McFadden GI, Sundriyal S, Anglin JL, Song Y, Moreno SN, Striepen B. Apicoplast isoprenoid precursor synthesis and the molecular basis of fosmidomycin resistance in Toxoplasma gondii. The Journal of Experimental Medicine. 208: 1547-59. PMID 21690250 DOI: 10.1084/Jem.20110039  0.417
2011 Brooks CF, Francia ME, Gissot M, Croken MM, Kim K, Striepen B. Toxoplasma gondii sequesters centromeres to a specific nuclear region throughout the cell cycle. Proceedings of the National Academy of Sciences of the United States of America. 108: 3767-72. PMID 21321216 DOI: 10.1073/Pnas.1006741108  0.356
2009 Chtanova T, Han SJ, Schaeffer M, van Dooren GG, Herzmark P, Striepen B, Robey EA. Dynamics of T cell, antigen-presenting cell, and pathogen interactions during recall responses in the lymph node. Immunity. 31: 342-55. PMID 19699173 DOI: 10.1016/j.immuni.2009.06.023  0.43
2009 Schaeffer M, Han SJ, Chtanova T, van Dooren GG, Herzmark P, Chen Y, Roysam B, Striepen B, Robey EA. Dynamic imaging of T cell-parasite interactions in the brains of mice chronically infected with Toxoplasma gondii. Journal of Immunology (Baltimore, Md. : 1950). 182: 6379-93. PMID 19414791 DOI: 10.4049/Jimmunol.0804307  0.502
2009 Breinich MS, Ferguson DJ, Foth BJ, van Dooren GG, Lebrun M, Quon DV, Striepen B, Bradley PJ, Frischknecht F, Carruthers VB, Meissner M. A dynamin is required for the biogenesis of secretory organelles in Toxoplasma gondii. Current Biology : Cb. 19: 277-86. PMID 19217293 DOI: 10.1016/j.cub.2009.01.039  0.356
2008 Denkers EY, Striepen B. Deploying parasite profilin on a mission of invasion and danger. Cell Host & Microbe. 3: 61-3. PMID 18312839 DOI: 10.1016/J.Chom.2008.01.003  0.439
2008 Gubbels MJ, Lehmann M, Muthalagi M, Jerome ME, Brooks CF, Szatanek T, Flynn J, Parrot B, Radke J, Striepen B, White MW. Forward genetic analysis of the apicomplexan cell division cycle in Toxoplasma gondii. Plos Pathogens. 4: e36. PMID 18282098 DOI: 10.1371/Journal.Ppat.0040036  0.349
2007 Striepen B, Jordan CN, Reiff S, van Dooren GG. Building the perfect parasite: cell division in apicomplexa. Plos Pathogens. 3: e78. PMID 17604449 DOI: 10.1371/journal.ppat.0030078  0.372
2006 Vaishnava S, Striepen B. The cell biology of secondary endosymbiosis--how parasites build, divide and segregate the apicoplast. Molecular Microbiology. 61: 1380-7. PMID 16968220 DOI: 10.1111/j.1365-2958.2006.05343.x  0.377
2006 Andrade RM, Wessendarp M, Gubbels MJ, Striepen B, Subauste CS. CD40 induces macrophage anti-Toxoplasma gondii activity by triggering autophagy-dependent fusion of pathogen-containing vacuoles and lysosomes Journal of Clinical Investigation. 116: 2366-2377. PMID 16955139 DOI: 10.1172/Jci28796  0.362
2006 Mazumdar J, Wilson EH, Masek K, Hunter CA, Striepen B. Apicoplast fatty acid synthesis is essential for organelle biogenesis and parasite survival in Toxoplasma gondii Proceedings of the National Academy of Sciences of the United States of America. 103: 13192-13197. PMID 16920791 DOI: 10.1073/Pnas.0603391103  0.324
2005 Egan CE, Dalton JE, Andrew EM, Smith JE, Gubbels MJ, Striepen B, Carding SR. A requirement for the Vgamma1+ subset of peripheral gammadelta T cells in the control of the systemic growth of Toxoplasma gondii and infection-induced pathology. Journal of Immunology (Baltimore, Md. : 1950). 175: 8191-9. PMID 16339558 DOI: 10.4049/Jimmunol.175.12.8191  0.524
2005 Vaishnava S, Morrison DP, Gaji RY, Murray JM, Entzeroth R, Howe DK, Striepen B. Plastid segregation and cell division in the apicomplexan parasite Sarcocystis neurona. Journal of Cell Science. 118: 3397-407. PMID 16079283 DOI: 10.1242/jcs.02458  0.351
2005 White MW, Jerome ME, Vaishnava S, Guerini M, Behnke M, Striepen B. Genetic rescue of a Toxoplasma gondii conditional cell cycle mutant. Molecular Microbiology. 55: 1060-71. PMID 15686554 DOI: 10.1111/j.1365-2958.2004.04471.x  0.341
2005 Gubbels MJ, Striepen B, Shastri N, Turkoz M, Robey EA. Class I major histocompatibility complex presentation of antigens that escape from the parasitophorous vacuole of Toxoplasma gondii. Infection and Immunity. 73: 703-11. PMID 15664908 DOI: 10.1128/Iai.73.2.703-711.2005  0.503
2004 Gubbels MJ, Striepen B. Studying the cell biology of apicomplexan parasites using fluorescent proteins. Microscopy and Microanalysis : the Official Journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 10: 568-79. PMID 15525431 DOI: 10.1017/S1431927604040899  0.316
2003 Gubbels MJ, Li C, Striepen B. High-throughput growth assay for Toxoplasma gondii using yellow fluorescent protein. Antimicrobial Agents and Chemotherapy. 47: 309-16. PMID 12499207 DOI: 10.1128/Aac.47.1.309-316.2003  0.304
2003 Drozdowicz YM, Shaw M, Nishi M, Striepen B, Liwinski HA, Roos DS, Rea PA. Isolation and characterization of TgVP1, a type I vacuolar H+-translocating pyrophosphatase from Toxoplasma gondii. The dynamics of its subcellular localization and the cellular effects of a diphosphonate inhibitor. The Journal of Biological Chemistry. 278: 1075-85. PMID 12411435 DOI: 10.1074/jbc.M209436200  0.322
2002 Neudeck A, Stachelhaus S, Nischik N, Striepen B, Reichmann G, Fischer HG. Expression variance, biochemical and immunological properties of Toxoplasma gondii dense granule protein GRA7. Microbes and Infection. 4: 581-90. PMID 12048027 DOI: 10.1016/s1286-4579(02)01576-9  0.463
2002 Hu K, Mann T, Striepen B, Beckers CJ, Roos DS, Murray JM. Daughter cell assembly in the protozoan parasite Toxoplasma gondii. Molecular Biology of the Cell. 13: 593-606. PMID 11854415 DOI: 10.1091/mbc.01-06-0309  0.446
2002 Roos DS, Crawford MJ, Donald RG, Fraunholz M, Harb OS, He CY, Kissinger JC, Shaw MK, Striepen B. Mining the Plasmodium genome database to define organellar function: what does the apicoplast do? Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 357: 35-46. PMID 11839180 DOI: 10.1098/rstb.2001.1047  0.335
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