Philipp J. Keller - Publications

Affiliations: 
2011- Janelia Farm Research Campus - HHMI, Ashburn, VA, United States 

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Keller JP, Marvin JS, Lacin H, Lemon WC, Shea J, Kim S, Lee RT, Koyama M, Keller PJ, Looger LL. In vivo glucose imaging in multiple model organisms with an engineered single-wavelength sensor. Cell Reports. 35: 109284. PMID 34161775 DOI: 10.1016/j.celrep.2021.109284  1
2021 Tyser RCV, Ibarra-Soria X, McDole K, A Jayaram S, Godwin J, van den Brand TAH, Miranda AMA, Scialdone A, Keller PJ, Marioni JC, Srinivas S. Characterization of a common progenitor pool of the epicardium and myocardium. Science (New York, N.Y.). PMID 33414188 DOI: 10.1126/science.abb2986  0.4
2020 Azizi A, Herrmann A, Wan Y, Buse SJ, Keller PJ, Goldstein RE, Harris WA. Nuclear crowding and nonlinear diffusion during interkinetic nuclear migration in the zebrafish retina. Elife. 9. PMID 33021471 DOI: 10.7554/eLife.58635  0.52
2019 Sato Y, Hilbert L, Oda H, Wan Y, Heddleston JM, Chew TL, Zaburdaev V, Keller P, Lionnet T, Vastenhouw N, Kimura H. Histone H3K27 acetylation precedes active transcription during zebrafish zygotic genome activation as revealed by live-cell analysis. Development (Cambridge, England). 146. PMID 31570370 DOI: 10.1242/Dev.179127  0.44
2019 Wan Y, Wei Z, Looger LL, Koyama M, Druckmann S, Keller PJ. Single-Cell Reconstruction of Emerging Population Activity in an Entire Developing Circuit. Cell. PMID 31564455 DOI: 10.1016/J.Cell.2019.08.039  0.44
2019 Hörl D, Rojas Rusak F, Preusser F, Tillberg P, Randel N, Chhetri RK, Cardona A, Keller PJ, Harz H, Leonhardt H, Treier M, Preibisch S. BigStitcher: reconstructing high-resolution image datasets of cleared and expanded samples. Nature Methods. PMID 31384047 DOI: 10.1038/S41592-019-0501-0  0.36
2019 Wan Y, McDole K, Keller PJ. Light-Sheet Microscopy and Its Potential for Understanding Developmental Processes. Annual Review of Cell and Developmental Biology. PMID 31299171 DOI: 10.1146/Annurev-Cellbio-100818-125311  0.84
2019 Djabrayan NJ, Smits CM, Krajnc M, Stern T, Yamada S, Lemon WC, Keller PJ, Rushlow CA, Shvartsman SY. Metabolic Regulation of Developmental Cell Cycles and Zygotic Transcription. Current Biology : Cb. PMID 30880009 DOI: 10.1016/J.Cub.2019.02.028  1
2018 Vladimirov N, Wang C, Höckendorf B, Pujala A, Tanimoto M, Mu Y, Yang CT, Wittenbach JD, Freeman J, Preibisch S, Koyama M, Keller PJ, Ahrens MB. Brain-wide circuit interrogation at the cellular level guided by online analysis of neuronal function. Nature Methods. 15: 1117-1125. PMID 30504888 DOI: 10.1038/S41592-018-0221-X  0.44
2018 Royer LA, Lemon WC, Chhetri RK, Keller PJ. A practical guide to adaptive light-sheet microscopy. Nature Protocols. PMID 30367170 DOI: 10.1038/S41596-018-0043-4  1
2018 McDole K, Guignard L, Amat F, Berger A, Malandain G, Royer LA, Turaga SC, Branson K, Keller PJ. In Toto Imaging and Reconstruction of Post-Implantation Mouse Development at the Single-Cell Level. Cell. PMID 30318151 DOI: 10.1016/J.Cell.2018.09.031  0.44
2018 Khairy K, Lemon W, Amat F, Keller PJ. A Preferred Curvature-Based Continuum Mechanics Framework for Modeling Embryogenesis. Biophysical Journal. 114: 267-277. PMID 29401426 DOI: 10.1016/J.Bpj.2017.11.015  0.44
2017 Grimm JB, Muthusamy AK, Liang Y, Brown TA, Lemon WC, Patel R, Lu R, Macklin JJ, Keller PJ, Ji N, Lavis LD. A general method to fine-tune fluorophores for live-cell and in vivo imaging. Nature Methods. PMID 28869757 DOI: 10.1038/Nmeth.4403  1
2016 Royer LA, Lemon WC, Chhetri RK, Wan Y, Coleman M, Myers EW, Keller PJ. Adaptive light-sheet microscopy for long-term, high-resolution imaging in living organisms. Nature Biotechnology. PMID 27798562 DOI: 10.1038/Nbt.3708  1
2016 Chhetri RK, Keller PJ. Imaging far and wide. Elife. 5. PMID 27661777 DOI: 10.7554/Elife.21072  0.36
2016 Paksa A, Bandemer J, Hoeckendorf B, Razin N, Tarbashevich K, Minina S, Meyen D, Biundo A, Leidel SA, Peyrieras N, Gov NS, Keller PJ, Raz E. Repulsive cues combined with physical barriers and cell-cell adhesion determine progenitor cell positioning during organogenesis. Nature Communications. 7: 11288. PMID 27088892 DOI: 10.1038/Ncomms11288  1
2016 Liu Z, Keller PJ. Emerging Imaging and Genomic Tools for Developmental Systems Biology. Developmental Cell. 36: 597-610. PMID 27003934 DOI: 10.1016/J.Devcel.2016.02.016  1
2016 Stegmaier J, Amat F, Lemon WC, McDole K, Wan Y, Teodoro G, Mikut R, Keller PJ. Real-Time Three-Dimensional Cell Segmentation in Large-Scale Microscopy Data of Developing Embryos. Developmental Cell. 36: 225-40. PMID 26812020 DOI: 10.1016/J.Devcel.2015.12.028  1
2016 Chhetri R, Amat F, Wan Y, Höckendorf B, Lemon WC, Keller PJ. Whole-animal imaging with high spatio-temporal resolution Proceedings of Spie. 9720. DOI: 10.1117/12.2212564  1
2015 Kim SY, Cho JH, Murray E, Bakh N, Choi H, Ohn K, Ruelas L, Hubbert A, McCue M, Vassallo SL, Keller PJ, Chung K. Stochastic electrotransport selectively enhances the transport of highly electromobile molecules. Proceedings of the National Academy of Sciences of the United States of America. 112: E6274-83. PMID 26578787 DOI: 10.1073/Pnas.1510133112  1
2015 Chhetri RK, Amat F, Wan Y, Höckendorf B, Lemon WC, Keller PJ. Whole-animal functional and developmental imaging with isotropic spatial resolution. Nature Methods. PMID 26501515 DOI: 10.1038/Nmeth.3632  1
2015 Amat F, Höckendorf B, Wan Y, Lemon WC, McDole K, Keller PJ. Efficient processing and analysis of large-scale light-sheet microscopy data. Nature Protocols. 10: 1679-96. PMID 26426501 DOI: 10.1038/Nprot.2015.111  1
2015 Lemon WC, Pulver SR, Höckendorf B, McDole K, Branson K, Freeman J, Keller PJ. Whole-central nervous system functional imaging in larval Drosophila. Nature Communications. 6: 7924. PMID 26263051 DOI: 10.1038/Ncomms8924  1
2015 Keller PJ, Ahrens MB. Visualizing whole-brain activity and development at the single-cell level using light-sheet microscopy. Neuron. 85: 462-83. PMID 25654253 DOI: 10.1016/J.Neuron.2014.12.039  1
2015 Keller PJ, Ahrens MB, Freeman J. Light-sheet imaging for systems neuroscience. Nature Methods. 12: 27-9. PMID 25549267 DOI: 10.1038/Nmeth.3214  1
2015 Khairy K, Lemon WC, Amat F, Keller PJ. Light sheet-based imaging and analysis of early embryogenesis in the fruit fly. Methods in Molecular Biology (Clifton, N.J.). 1189: 79-97. PMID 25245688 DOI: 10.1007/978-1-4939-1164-6_6  1
2015 Lemon WC, Keller PJ. Live imaging of nervous system development and function using light-sheet microscopy. Molecular Reproduction and Development. 82: 605-18. PMID 23996352 DOI: 10.1002/Mrd.22258  1
2015 Keller PJ. Reconstructing nervous system development and function with light-sheet microscopy Cleo: Qels - Fundamental Science, Cleo_qels 2015. 1551p. DOI: 10.1364/CLEO_AT.2015.JTu1D.2  1
2015 Li X, Zhou Z, Keller P, Zeng H, Liu T, Peng H. Interactive exemplar-based segmentation toolkit for biomedical image analysis Proceedings - International Symposium On Biomedical Imaging. 2015: 168-171. DOI: 10.1109/ISBI.2015.7163842  1
2015 Lemon WC, Pulver SR, Höckendorf B, McDole K, Branson K, Freeman J, Keller PJ. Whole-central nervous system functional imaging in larval Drosophila Nature Communications. 6. DOI: 10.1038/ncomms8924  1
2014 Höckendorf B, Lavis LD, Keller PJ. Making biology transparent. Nature Biotechnology. 32: 1104-5. PMID 25380446 DOI: 10.1038/Nbt.3061  1
2014 Lauri A, Brunet T, Handberg-Thorsager M, Fischer AH, Simakov O, Steinmetz PR, Tomer R, Keller PJ, Arendt D. Development of the annelid axochord: insights into notochord evolution. Science (New York, N.Y.). 345: 1365-8. PMID 25214631 DOI: 10.1126/Science.1253396  1
2014 Crespo CL, Vernieri C, Keller PJ, Garrè M, Bender JR, Wittbrodt J, Pardi R. The PAR complex controls the spatiotemporal dynamics of F-actin and the MTOC in directionally migrating leukocytes. Journal of Cell Science. 127: 4381-95. PMID 25179599 DOI: 10.1242/Jcs.146217  1
2014 Vladimirov N, Mu Y, Kawashima T, Bennett DV, Yang CT, Looger LL, Keller PJ, Freeman J, Ahrens MB. Light-sheet functional imaging in fictively behaving zebrafish. Nature Methods. 11: 883-4. PMID 25068735 DOI: 10.1038/Nmeth.3040  0.32
2014 Amat F, Lemon W, Mossing DP, McDole K, Wan Y, Branson K, Myers EW, Keller PJ. Fast, accurate reconstruction of cell lineages from large-scale fluorescence microscopy data. Nature Methods. 11: 951-8. PMID 25042785 DOI: 10.1038/Nmeth.3036  1
2014 Ichikawa T, Nakazato K, Keller PJ, Kajiura-Kobayashi H, Stelzer EH, Mochizuki A, Nonaka S. Live imaging and quantitative analysis of gastrulation in mouse embryos using light-sheet microscopy and 3D tracking tools. Nature Protocols. 9: 575-85. PMID 24525751 DOI: 10.1038/Nprot.2014.035  1
2013 Ichikawa T, Nakazato K, Keller PJ, Kajiura-Kobayashi H, Stelzer EH, Mochizuki A, Nonaka S. Live imaging of whole mouse embryos during gastrulation: migration analyses of epiblast and mesodermal cells. Plos One. 8: e64506. PMID 23861733 DOI: 10.1371/Journal.Pone.0064506  1
2013 Keller PJ. Imaging morphogenesis: technological advances and biological insights. Science (New York, N.Y.). 340: 1234168. PMID 23744952 DOI: 10.1126/Science.1234168  1
2013 Amat F, Keller PJ. Towards comprehensive cell lineage reconstructions in complex organisms using light-sheet microscopy. Development, Growth & Differentiation. 55: 563-78. PMID 23621671 DOI: 10.1111/Dgd.12063  1
2013 Ahrens MB, Orger MB, Robson DN, Li JM, Keller PJ. Whole-brain functional imaging at cellular resolution using light-sheet microscopy. Nature Methods. 10: 413-20. PMID 23524393 DOI: 10.1038/Nmeth.2434  1
2013 Keller PJ. In vivo imaging of zebrafish embryogenesis. Methods (San Diego, Calif.). 62: 268-78. PMID 23523701 DOI: 10.1016/J.Ymeth.2013.03.015  1
2013 Amat F, Myers EW, Keller PJ. Fast and robust optical flow for time-lapse microscopy using super-voxels. Bioinformatics (Oxford, England). 29: 373-80. PMID 23242263 DOI: 10.1093/Bioinformatics/Bts706  1
2013 Tomer R, Khairy K, Keller PJ. Light sheet microscopy in cell biology. Methods in Molecular Biology (Clifton, N.J.). 931: 123-37. PMID 23027001 DOI: 10.1007/978-1-62703-056-4_7  1
2013 Amat F, Keller PJ. 3D Haar-like elliptical features for object classification in microscopy Proceedings - International Symposium On Biomedical Imaging. 1194-1197. DOI: 10.1109/ISBI.2013.6556694  1
2012 Khmelinskii A, Keller PJ, Bartosik A, Meurer M, Barry JD, Mardin BR, Kaufmann A, Trautmann S, Wachsmuth M, Pereira G, Huber W, Schiebel E, Knop M. Tandem fluorescent protein timers for in vivo analysis of protein dynamics. Nature Biotechnology. 30: 708-14. PMID 22729030 DOI: 10.1038/Nbt.2281  1
2012 Tomer R, Khairy K, Amat F, Keller PJ. Quantitative high-speed imaging of entire developing embryos with simultaneous multiview light-sheet microscopy. Nature Methods. 9: 755-63. PMID 22660741 DOI: 10.1038/Nmeth.2062  1
2012 Keller PJ, Dodt HU. Light sheet microscopy of living or cleared specimens. Current Opinion in Neurobiology. 22: 138-43. PMID 21925871 DOI: 10.1016/J.Conb.2011.08.003  1
2011 Kanodia JS, Kim Y, Tomer R, Khan Z, Chung K, Storey JD, Lu H, Keller PJ, Shvartsman SY. A computational statistics approach for estimating the spatial range of morphogen gradients. Development (Cambridge, England). 138: 4867-74. PMID 22007136 DOI: 10.1242/Dev.071571  1
2011 Keller PJ, Schmidt AD, Wittbrodt J, Stelzer EH. Digital scanned laser light-sheet fluorescence microscopy (DSLM) of zebrafish and Drosophila embryonic development. Cold Spring Harbor Protocols. 2011: 1235-43. PMID 21969622 DOI: 10.1101/Pdb.Prot065839  1
2011 Tomer R, Khairy K, Keller PJ. Shedding light on the system: studying embryonic development with light sheet microscopy. Current Opinion in Genetics & Development. 21: 558-65. PMID 21862314 DOI: 10.1016/J.Gde.2011.07.003  1
2011 Khairy K, Keller PJ. Reconstructing embryonic development. Genesis (New York, N.Y. : 2000). 49: 488-513. PMID 21140407 DOI: 10.1002/Dvg.20698  1
2010 Khmelinskii A, Keller PJ, Lorenz H, Schiebel E, Knop M. Segregation of yeast nuclear pores. Nature. 466: E1. PMID 20651645 DOI: 10.1038/Nature09255  1
2010 Keller PJ, Schmidt AD, Santella A, Khairy K, Bao Z, Wittbrodt J, Stelzer EH. Fast, high-contrast imaging of animal development with scanned light sheet-based structured-illumination microscopy. Nature Methods. 7: 637-42. PMID 20601950 DOI: 10.1038/Nmeth.1476  1
2010 Keller PJ, Stelzer EH. Digital scanned laser light sheet fluorescence microscopy. Cold Spring Harbor Protocols. 2010: pdb.top78. PMID 20439423 DOI: 10.1101/Pdb.Top78  1
2010 Brown KE, Keller PJ, Ramialison M, Rembold M, Stelzer EH, Loosli F, Wittbrodt J. Nlcam modulates midline convergence during anterior neural plate morphogenesis. Developmental Biology. 339: 14-25. PMID 20005219 DOI: 10.1016/J.Ydbio.2009.12.003  1
2009 Keller PJ, Knop M. Evolution of mutational robustness in the yeast genome: a link to essential genes and meiotic recombination hotspots. Plos Genetics. 5: e1000533. PMID 19557188 DOI: 10.1371/Journal.Pgen.1000533  1
2009 Keller PJ, Schmidt AD, Wittbrodt J, Stelzer EHK. The zebrafish digital embryo: In toto reconstruction of zebrafish early embryonic development with digital scanned laser light sheet fluorescence microscopy Progress in Biomedical Optics and Imaging - Proceedings of Spie. 7367. DOI: 10.1117/12.831496  1
2008 Keller PJ, Stelzer EH. Quantitative in vivo imaging of entire embryos with Digital Scanned Laser Light Sheet Fluorescence Microscopy. Current Opinion in Neurobiology. 18: 624-32. PMID 19375303 DOI: 10.1016/J.Conb.2009.03.008  1
2008 Keller PJ, Schmidt AD, Wittbrodt J, Stelzer EH. Reconstruction of zebrafish early embryonic development by scanned light sheet microscopy. Science (New York, N.Y.). 322: 1065-9. PMID 18845710 DOI: 10.1126/Science.1162493  1
2008 Keller PJ, Pampaloni F, Lattanzi G, Stelzer EH. Three-dimensional microtubule behavior in Xenopus egg extracts reveals four dynamic states and state-dependent elastic properties. Biophysical Journal. 95: 1474-86. PMID 18441022 DOI: 10.1529/Biophysj.107.128223  1
2007 Keller PJ, Pampaloni F, Stelzer EH. Three-dimensional preparation and imaging reveal intrinsic microtubule properties. Nature Methods. 4: 843-6. PMID 17828271 DOI: 10.1038/Nmeth1087  1
2006 Gordon O, Taxis C, Keller PJ, Benjak A, Stelzer EH, Simchen G, Knop M. Nud1p, the yeast homolog of Centriolin, regulates spindle pole body inheritance in meiosis. The Embo Journal. 25: 3856-68. PMID 16888627 DOI: 10.1038/Sj.Emboj.7601254  1
2006 Keller PJ, Pampaloni F, Stelzer EH. Life sciences require the third dimension. Current Opinion in Cell Biology. 18: 117-24. PMID 16387486 DOI: 10.1016/J.Ceb.2005.12.012  1
2005 Taxis C, Keller P, Kavagiou Z, Jensen LJ, Colombelli J, Bork P, Stelzer EH, Knop M. Spore number control and breeding in Saccharomyces cerevisiae: a key role for a self-organizing system. The Journal of Cell Biology. 171: 627-40. PMID 16286509 DOI: 10.1083/Jcb.200507168  1
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