| Year |
Citation |
Score |
| 2024 |
Shay TF, Jang S, Brittain TJ, Chen X, Walker B, Tebbutt C, Fan Y, Wolfe DA, Arokiaraj CM, Sullivan EE, Ding X, Wang TY, Lei Y, Chuapoco MR, Chou TF, ... Gradinaru V, et al. Human cell surface-AAV interactomes identify LRP6 as blood-brain barrier transcytosis receptor and immune cytokine IL3 as AAV9 binder. Nature Communications. 15: 7853. PMID 39245720 DOI: 10.1038/s41467-024-52149-0 |
0.795 |
|
| 2024 |
Ding X, Chen X, Sullivan EE, Shay TF, Gradinaru V. Fast, accurate ranking of engineered proteins by target binding propensity using structure modeling. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 38582966 DOI: 10.1016/j.ymthe.2024.04.003 |
0.766 |
|
| 2024 |
Griffiths JA, Yoo BB, Thuy-Boun P, Cantu VJ, Weldon KC, Challis C, Sweredoski MJ, Chan KY, Thron TM, Sharon G, Moradian A, Humphrey G, Zhu Q, Shaffer JP, Wolan DW, ... ... Gradinaru V, et al. Peripheral neuronal activation shapes the microbiome and alters gut physiology. Cell Reports. 43: 113953. PMID 38517896 DOI: 10.1016/j.celrep.2024.113953 |
0.537 |
|
| 2023 |
Coughlin GM, Borsos M, Appling N, Barcelona BH, Mayfield AMH, Mackey ED, Eser RA, Chen X, Kumar SR, Gradinaru V. Spatial genomics of AAVs reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo. Biorxiv : the Preprint Server For Biology. PMID 38187707 DOI: 10.1101/2023.12.23.573214 |
0.631 |
|
| 2023 |
Henrickson A, Ding X, Seal AG, Qu Z, Tomlinson L, Forsey J, Gradinaru V, Oka K, Demeler B. Characterization and quantification of adeno-associated virus capsid-loading states by multi-wavelength analytical ultracentrifugation with UltraScan. Nanomedicine (London, England). 18: 1519-1534. PMID 37877696 DOI: 10.2217/nnm-2023-0156 |
0.724 |
|
| 2023 |
Chuapoco MR, Flytzanis NC, Goeden N, Christopher Octeau J, Roxas KM, Chan KY, Scherrer J, Winchester J, Blackburn RJ, Campos LJ, Man KNM, Sun J, Chen X, Lefevre A, Singh VP, ... ... Gradinaru V, et al. Adeno-associated viral vectors for functional intravenous gene transfer throughout the non-human primate brain. Nature Nanotechnology. PMID 37430038 DOI: 10.1038/s41565-023-01419-x |
0.764 |
|
| 2023 |
Campos LJ, Arokiaraj CM, Chuapoco MR, Chen X, Goeden N, Gradinaru V, Fox AS. Advances in AAV technology for delivering genetically encoded cargo to the nonhuman primate nervous system. Current Research in Neurobiology. 4: 100086. PMID 37397806 DOI: 10.1016/j.crneur.2023.100086 |
0.646 |
|
| 2023 |
Chen X, Wolfe DA, Bindu DS, Zhang M, Taskin N, Goertsen D, Shay TF, Sullivan EE, Huang SF, Ravindra Kumar S, Arokiaraj CM, Plattner VM, Campos LJ, Mich JK, Monet D, ... ... Gradinaru V, et al. Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates. Nature Communications. 14: 3345. PMID 37291094 DOI: 10.1038/s41467-023-38582-7 |
0.795 |
|
| 2023 |
Shay TF, Sullivan EE, Ding X, Chen X, Ravindra Kumar S, Goertsen D, Brown D, Crosby A, Vielmetter J, Borsos M, Wolfe DA, Lam AW, Gradinaru V. Primate-conserved carbonic anhydrase IV and murine-restricted LY6C1 enable blood-brain barrier crossing by engineered viral vectors. Science Advances. 9: eadg6618. PMID 37075114 DOI: 10.1126/sciadv.adg6618 |
0.795 |
|
| 2023 |
Chuapoco M, Flytzanis N, Goeden N, Octeau J, Roxas K, Chan K, Scherrer J, Winchester J, Blackburn R, Campos L, Man KN, Sun J, Chen X, Lefevre A, Singh V, ... ... Gradinaru V, et al. Intravenous functional gene transfer throughout the brain of non-human primates using AAV. Research Square. PMID 36789432 DOI: 10.21203/rs.3.rs-1370972/v1 |
0.651 |
|
| 2023 |
Chen X, Wolfe DA, Sivadasan Bindu D, Zhang M, Taskin N, Goertsen D, Shay TF, Sullivan E, Huang SF, Ravindra Kumar S, Arokiaraj CM, Plattner V, Campos LJ, Mich J, Monet D, ... ... Gradinaru V, et al. Functional gene delivery to and across brain vasculature of systemic AAVs with endothelial-specific tropism in rodents and broad tropism in primates. Biorxiv : the Preprint Server For Biology. PMID 36711773 DOI: 10.1101/2023.01.12.523844 |
0.794 |
|
| 2023 |
Jang MJ, Coughlin GM, Jackson CR, Chen X, Chuapoco MR, Vendemiatti JL, Wang AZ, Gradinaru V. Spatial transcriptomics for profiling the tropism of viral vectors in tissues. Nature Biotechnology. PMID 36702899 DOI: 10.1038/s41587-022-01648-w |
0.663 |
|
| 2022 |
Jang S, Shen HK, Ding X, Miles TF, Gradinaru V. Structural basis of receptor usage by the engineered capsid AAV-PHP.eB. Molecular Therapy. Methods & Clinical Development. 26: 343-354. PMID 36034770 DOI: 10.1016/j.omtm.2022.07.011 |
0.741 |
|
| 2022 |
Chen X, Ravindra Kumar S, Adams CD, Yang D, Wang T, Wolfe DA, Arokiaraj CM, Ngo V, Campos LJ, Griffiths JA, Ichiki T, Mazmanian SK, Osborne PB, Keast JR, Miller CT, ... ... Gradinaru V, et al. Engineered AAVs for non-invasive gene delivery to rodent and non-human primate nervous systems. Neuron. PMID 35643078 DOI: 10.1016/j.neuron.2022.05.003 |
0.63 |
|
| 2022 |
Challis RC, Ravindra Kumar S, Chen X, Goertsen D, Coughlin GM, Hori AM, Chuapoco MR, Otis TS, Miles TF, Gradinaru V. Adeno-Associated Virus Toolkit to Target Diverse Brain Cells. Annual Review of Neuroscience. PMID 35440143 DOI: 10.1146/annurev-neuro-111020-100834 |
0.799 |
|
| 2021 |
Cui L, Guo J, Cranfill SL, Gautam M, Bhattarai J, Olson W, Beattie K, Challis RC, Wu Q, Song X, Raabe T, Gradinaru V, Ma M, Liu Q, Luo W. Glutamate in primary afferents is required for itch transmission. Neuron. PMID 34986325 DOI: 10.1016/j.neuron.2021.12.007 |
0.756 |
|
| 2021 |
Goertsen D, Flytzanis NC, Goeden N, Chuapoco MR, Cummins A, Chen Y, Fan Y, Zhang Q, Sharma J, Duan Y, Wang L, Feng G, Chen Y, Ip NY, Pickel J, ... Gradinaru V, et al. AAV capsid variants with brain-wide transgene expression and decreased liver targeting after intravenous delivery in mouse and marmoset. Nature Neuroscience. PMID 34887588 DOI: 10.1038/s41593-021-00969-4 |
0.326 |
|
| 2021 |
Kahan A, Greenbaum A, Jang MJ, Robinson JE, Cho JR, Chen X, Kassraian P, Wagenaar DA, Gradinaru V. Light-guided sectioning for precise in situ localization and tissue interface analysis for brain-implanted optical fibers and GRIN lenses. Cell Reports. 36: 109744. PMID 34592157 DOI: 10.1016/j.celrep.2021.109744 |
0.64 |
|
| 2021 |
Smith EJ, Farshim PP, Flomen R, Jones ST, McAteer SJ, Deverman BE, Gradinaru V, Bates GP. Use of high-content imaging to quantify transduction of AAV-PHP viruses in the brain following systemic delivery. Brain Communications. 3: fcab105. PMID 34131644 DOI: 10.1093/braincomms/fcab105 |
0.307 |
|
| 2021 |
Mich JK, Graybuck LT, Hess EE, Mahoney JT, Kojima Y, Ding Y, Somasundaram S, Miller JA, Kalmbach BE, Radaelli C, Gore BB, Weed N, Omstead V, Bishaw Y, Shapovalova NV, ... ... Gradinaru V, et al. Functional enhancer elements drive subclass-selective expression from mouse to primate neocortex. Cell Reports. 34: 108754. PMID 33789096 DOI: 10.1016/j.celrep.2021.108754 |
0.656 |
|
| 2021 |
Graybuck LT, Daigle TL, Sedeño-Cortés AE, Walker M, Kalmbach B, Lenz GH, Morin E, Nguyen TN, Garren E, Bendrick JL, Kim TK, Zhou T, Mortrud M, Yao S, Siverts LA, ... ... Gradinaru V, et al. Enhancer viruses for combinatorial cell-subclass-specific labeling. Neuron. PMID 33789083 DOI: 10.1016/j.neuron.2021.03.011 |
0.675 |
|
| 2021 |
Cho JR, Chen X, Kahan A, Robinson JE, Wagenaar DA, Gradinaru V. Dorsal raphe dopamine neurons signal motivational salience dependent on internal state, expectation, and behavioral context. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33563725 DOI: 10.1523/JNEUROSCI.2690-20.2021 |
0.639 |
|
| 2020 |
Badimon A, Strasburger HJ, Ayata P, Chen X, Nair A, Ikegami A, Hwang P, Chan AT, Graves SM, Uweru JO, Ledderose C, Kutlu MG, Wheeler MA, Kahan A, Ishikawa M, ... ... Gradinaru V, et al. Negative feedback control of neuronal activity by microglia. Nature. PMID 32999463 DOI: 10.1038/s41586-020-2777-8 |
0.763 |
|
| 2020 |
Gradinaru V. Expanding the brain researcher's toolkit. Science (New York, N.Y.). 369: 637. PMID 32764063 DOI: 10.1126/science.abd2660 |
0.303 |
|
| 2020 |
Seo JW, Ingham ES, Mahakian L, Tumbale S, Wu B, Aghevlian S, Shams S, Baikoghli M, Jain P, Ding X, Goeden N, Dobreva T, Flytzanis NC, Chavez M, Singhal K, ... ... Gradinaru V, et al. Positron emission tomography imaging of novel AAV capsids maps rapid brain accumulation. Nature Communications. 11: 2102. PMID 32355221 DOI: 10.1038/S41467-020-15818-4 |
0.772 |
|
| 2020 |
Ravindra Kumar S, Miles TF, Chen X, Brown D, Dobreva T, Huang Q, Ding X, Luo Y, Einarsson PH, Greenbaum A, Jang MJ, Deverman BE, Gradinaru V. Multiplexed Cre-dependent selection yields systemic AAVs for targeting distinct brain cell types. Nature Methods. PMID 32313222 DOI: 10.1038/S41592-020-0799-7 |
0.798 |
|
| 2020 |
Rauch JN, Luna G, Guzman E, Audouard M, Challis C, Sibih YE, Leshuk C, Hernandez I, Wegmann S, Hyman BT, Gradinaru V, Kampmann M, Kosik KS. LRP1 is a master regulator of tau uptake and spread. Nature. 580: 381-385. PMID 32296178 DOI: 10.1038/S41586-020-2156-5 |
0.558 |
|
| 2020 |
Yao S, Yuan P, Ouellette B, Zhou T, Mortrud M, Balaram P, Chatterjee S, Wang Y, Daigle TL, Tasic B, Kuang X, Gong H, Luo Q, Zeng S, Curtright A, ... ... Gradinaru V, et al. RecV recombinase system for in vivo targeted optogenomic modifications of single cells or cell populations. Nature Methods. PMID 32203389 DOI: 10.1038/S41592-020-0774-3 |
0.401 |
|
| 2020 |
Challis C, Hori A, Sampson TR, Yoo BB, Challis RC, Hamilton AM, Mazmanian SK, Volpicelli-Daley LA, Gradinaru V. Gut-seeded α-synuclein fibrils promote gut dysfunction and brain pathology specifically in aged mice. Nature Neuroscience. PMID 32066981 DOI: 10.1038/S41593-020-0589-7 |
0.746 |
|
| 2020 |
Sampson TR, Challis C, Jain N, Moiseyenko A, Ladinsky MS, Shastri GG, Thron T, Needham BD, Horvath I, Debelius JW, Janssen S, Knight R, Wittung-Stafshede P, Gradinaru V, Chapman M, et al. A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice. Elife. 9. PMID 32043464 DOI: 10.7554/Elife.53111 |
0.558 |
|
| 2020 |
Ueda HR, Ertürk A, Chung K, Gradinaru V, Chédotal A, Tomancak P, Keller PJ. Tissue clearing and its applications in neuroscience. Nature Reviews. Neuroscience. PMID 31896771 DOI: 10.1038/S41583-019-0250-1 |
0.319 |
|
| 2020 |
Sampson TR, Challis C, Jain N, Moiseyenko A, Ladinsky MS, Shastri GG, Thron T, Needham BD, Horvath I, Debelius JW, Janssen S, Knight R, Wittung-Stafshede P, Gradinaru V, Chapman M, et al. Author response: A gut bacterial amyloid promotes α-synuclein aggregation and motor impairment in mice Elife. DOI: 10.7554/Elife.53111.Sa2 |
0.509 |
|
| 2019 |
Patriarchi T, Cho JR, Merten K, Marley A, Broussard GJ, Liang R, Williams J, Nimmerjahn A, von Zastrow M, Gradinaru V, Tian L. Imaging neuromodulators with high spatiotemporal resolution using genetically encoded indicators. Nature Protocols. PMID 31732722 DOI: 10.1038/S41596-019-0239-2 |
0.371 |
|
| 2019 |
Bedbrook CN, Yang KK, Robinson JE, Mackey ED, Gradinaru V, Arnold FH. Machine learning-guided channelrhodopsin engineering enables minimally invasive optogenetics. Nature Methods. PMID 31611694 DOI: 10.1038/S41592-019-0583-8 |
0.431 |
|
| 2019 |
Song A, Dai W, Jang MJ, Medrano L, Li Z, Zhao H, Shao M, Tan J, Li A, Ning T, Miller MM, Armstrong B, Huss JM, Zhu Y, Liu Y, ... Gradinaru V, et al. Low- and high-thermogenic brown adipocyte subpopulations coexist in murine adipose tissue. The Journal of Clinical Investigation. PMID 31573981 DOI: 10.1172/Jci129167 |
0.726 |
|
| 2019 |
Ramirez-Zamora A, Giordano J, Boyden ES, Gradinaru V, Gunduz A, Starr PA, Sheth SA, McIntyre CC, Fox MD, Vitek J, Vedam-Mai V, Akbar U, Almeida L, Bronte-Stewart HM, Mayberg HS, et al. Proceedings of the Sixth Deep Brain Stimulation Think Tank Modulation of Brain Networks and Application of Advanced Neuroimaging, Neurophysiology, and Optogenetics. Frontiers in Neuroscience. 13: 936. PMID 31572109 DOI: 10.3389/Fnins.2019.00936 |
0.361 |
|
| 2019 |
Robinson JE, Coughlin GM, Hori AM, Cho JR, Mackey ED, Turan Z, Patriarchi T, Tian L, Gradinaru V. Optical dopamine monitoring with dLight1 reveals mesolimbic phenotypes in a mouse model of neurofibromatosis type 1. Elife. 8. PMID 31545171 DOI: 10.7554/Elife.48983 |
0.42 |
|
| 2019 |
Challis RC, Kumar SR, Chan KY, Challis C, Beadle K, Jang MJ, Kim HM, Rajendran PS, Tompkins JD, Shivkumar K, Deverman BE, Gradinaru V. Publisher Correction: Systemic AAV vectors for widespread and targeted gene delivery in rodents. Nature Protocols. PMID 31312046 DOI: 10.1038/S41596-019-0155-5 |
0.732 |
|
| 2019 |
Rajendran PS, Challis RC, Fowlkes CC, Hanna P, Tompkins JD, Jordan MC, Hiyari S, Gabris-Weber BA, Greenbaum A, Chan KY, Deverman BE, Münzberg H, Ardell JL, Salama G, Gradinaru V, et al. Identification of peripheral neural circuits that regulate heart rate using optogenetic and viral vector strategies. Nature Communications. 10: 1944. PMID 31028266 DOI: 10.1038/S41467-019-09770-1 |
0.678 |
|
| 2019 |
Zeng J, Wang Y, Luo Z, Chang LC, Yoo JS, Yan H, Choi Y, Xie X, Deverman BE, Gradinaru V, Gupton SL, Zlokovic BV, Zhao Z, Jung JU. TRIM9-Mediated Resolution of Neuroinflammation Confers Neuroprotection upon Ischemic Stroke in Mice. Cell Reports. 27: 549-560.e6. PMID 30970257 DOI: 10.1016/J.Celrep.2018.12.055 |
0.329 |
|
| 2019 |
Challis RC, Ravindra Kumar S, Chan KY, Challis C, Beadle K, Jang MJ, Kim HM, Rajendran PS, Tompkins JD, Shivkumar K, Deverman BE, Gradinaru V. Systemic AAV vectors for widespread and targeted gene delivery in rodents. Nature Protocols. PMID 30626963 DOI: 10.1038/S41596-018-0097-3 |
0.765 |
|
| 2019 |
Robinson JE, Coughlin GM, Hori AM, Cho JR, Mackey ED, Turan Z, Patriarchi T, Tian L, Gradinaru V. Author response: Optical dopamine monitoring with dLight1 reveals mesolimbic phenotypes in a mouse model of neurofibromatosis type 1 Elife. DOI: 10.7554/Elife.48983.036 |
0.353 |
|
| 2018 |
Mano T, Albanese A, Dodt HU, Erturk A, Gradinaru V, Treweek JB, Miyawaki A, Chung K, Ueda HR. Whole-Brain Analysis of Cells and Circuits by Tissue Clearing and Light-Sheet Microscopy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 38: 9330-9337. PMID 30381424 DOI: 10.1523/Jneurosci.1677-18.2018 |
0.38 |
|
| 2018 |
Patriarchi T, Cho JR, Merten K, Howe MW, Marley A, Xiong WH, Folk RW, Broussard GJ, Liang R, Jang MJ, Zhong H, Dombeck D, von Zastrow M, Nimmerjahn A, Gradinaru V, et al. Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors. Science (New York, N.Y.). PMID 29853555 DOI: 10.1126/Science.Aat4422 |
0.745 |
|
| 2018 |
Gradinaru V, Treweek J, Overton K, Deisseroth K. Hydrogel-Tissue Chemistry: Principles and Applications. Annual Review of Biophysics. 47: 355-376. PMID 29792820 DOI: 10.1146/annurev-biophys-070317-032905 |
0.55 |
|
| 2018 |
Zelikowsky M, Hui M, Karigo T, Choe A, Yang B, Blanco MR, Beadle K, Gradinaru V, Deverman BE, Anderson DJ. The Neuropeptide Tac2 Controls a Distributed Brain State Induced by Chronic Social Isolation Stress. Cell. 173: 1265-1279.e19. PMID 29775595 DOI: 10.1016/J.Cell.2018.03.037 |
0.461 |
|
| 2018 |
Bedbrook CN, Deverman BE, Gradinaru V. Viral Strategies for Targeting the Central and Peripheral Nervous Systems. Annual Review of Neuroscience. PMID 29709207 DOI: 10.1146/Annurev-Neuro-080317-062048 |
0.405 |
|
| 2017 |
Ruan H, Brake J, Robinson JE, Liu Y, Jang M, Xiao C, Zhou C, Gradinaru V, Yang C. Deep tissue optical focusing and optogenetic modulation with time-reversed ultrasonically encoded light. Science Advances. 3: eaao5520. PMID 29226248 DOI: 10.1126/Sciadv.Aao5520 |
0.448 |
|
| 2017 |
Greenbaum A, Jang MJ, Challis C, Gradinaru V. Q&A: How can advances in tissue clearing and optogenetics contribute to our understanding of normal and diseased biology? Bmc Biology. 15: 87. PMID 28946882 DOI: 10.1186/S12915-017-0421-3 |
0.575 |
|
| 2017 |
Robinson JE, Gradinaru V. Dopaminergic dysfunction in neurodevelopmental disorders: recent advances and synergistic technologies to aid basic research. Current Opinion in Neurobiology. 48: 17-29. PMID 28850815 DOI: 10.1016/J.Conb.2017.08.003 |
0.415 |
|
| 2017 |
Chan KY, Jang MJ, Yoo BB, Greenbaum A, Ravi N, Wu WL, Sánchez-Guardado L, Lois C, Mazmanian SK, Deverman BE, Gradinaru V. Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems. Nature Neuroscience. PMID 28671695 DOI: 10.1038/Nn.4593 |
0.393 |
|
| 2017 |
Cho JR, Treweek JB, Robinson JE, Xiao C, Bremner LR, Greenbaum A, Gradinaru V. Dorsal Raphe Dopamine Neurons Modulate Arousal and Promote Wakefulness by Salient Stimuli. Neuron. PMID 28602690 DOI: 10.1016/J.Neuron.2017.05.020 |
0.75 |
|
| 2017 |
Allen WE, Kauvar IV, Chen MZ, Richman EB, Yang SJ, Chan K, Gradinaru V, Deverman BE, Luo L, Deisseroth K. Global Representations of Goal-Directed Behavior in Distinct Cell Types of Mouse Neocortex. Neuron. 94: 891-907.e6. PMID 28521139 DOI: 10.1016/J.Neuron.2017.04.017 |
0.758 |
|
| 2017 |
Bedbrook CN, Rice AJ, Yang KK, Ding X, Chen S, LeProust EM, Gradinaru V, Arnold FH. Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins. Proceedings of the National Academy of Sciences of the United States of America. PMID 28283661 DOI: 10.1073/Pnas.1700269114 |
0.743 |
|
| 2017 |
Ruan H, Brake J, Robinson JE, Jang M, Xiao C, Zhou C, Gradinaru V, Yang C. Optogenetic Control of Neural Activity with Time-Reversed Ultrasound Encoded Light Brain. DOI: 10.1364/Brain.2017.Brm3B.3 |
0.438 |
|
| 2017 |
Gradinaru V. On Brain Circuits and Tools: Switches for Locomotion, Reward, and a Viral-based Approach to Non-invasive Whole-brain Cargo Delivery Brain. DOI: 10.1364/Brain.2017.Brm2B.2 |
0.37 |
|
| 2017 |
Gradinaru V. Switches for multiple behavioral states and a viral-based approach to non-invasive whole-brain cargo delivery (Conference Presentation) Proceedings of Spie. 10194. DOI: 10.1117/12.2264147 |
0.454 |
|
| 2016 |
Sampson TR, Debelius JW, Thron T, Janssen S, Shastri GG, Ilhan ZE, Challis C, Schretter CE, Rocha S, Gradinaru V, Chesselet MF, Keshavarzian A, Shannon KM, Krajmalnik-Brown R, Wittung-Stafshede P, et al. Gut Microbiota Regulate Motor Deficits and Neuroinflammation in a Model of Parkinson's Disease. Cell. 167: 1469-1480.e12. PMID 27912057 DOI: 10.1016/J.Cell.2016.11.018 |
0.547 |
|
| 2016 |
Treweek JB, Gradinaru V. Extracting structural and functional features of widely distributed biological circuits with single cell resolution via tissue clearing and delivery vectors. Current Opinion in Biotechnology. 40: 193-207. PMID 27393829 DOI: 10.1016/j.copbio.2016.03.012 |
0.324 |
|
| 2016 |
Shah S, Lubeck E, Schwarzkopf M, He TF, Greenbaum A, Sohn CH, Lignell A, Choi HM, Gradinaru V, Pierce NA, Cai L. Single-molecule RNA detection at depth via hybridization chain reaction and tissue hydrogel embedding and clearing. Development (Cambridge, England). PMID 27342713 DOI: 10.1242/Dev.138560 |
0.311 |
|
| 2016 |
Xiao C, Cho JR, Zhou C, Treweek JB, Chan K, McKinney SL, Yang B, Gradinaru V. Cholinergic Mesopontine Signals Govern Locomotion and Reward through Dissociable Midbrain Pathways. Neuron. 90: 333-347. PMID 27100197 DOI: 10.1016/j.neuron.2016.03.028 |
0.318 |
|
| 2016 |
Deverman BE, Pravdo PL, Simpson BP, Kumar SR, Chan KY, Banerjee A, Wu WL, Yang B, Huber N, Pasca SP, Gradinaru V. Cre-dependent selection yields AAV variants for widespread gene transfer to the adult brain. Nature Biotechnology. PMID 26829320 DOI: 10.1038/Nbt.3440 |
0.39 |
|
| 2016 |
Deverman BE, Pravdo PL, Simpson BP, Kumar SR, Luo Y, Chan KY, Banerjee A, Wu W, Yang B, Huber N, Pasca SP, Gradinaru V. 252. Using Cre-Dependent In Vivo Selection to Identify AAV Variants That Enable Efficient and Widespread Gene Transfer to the Adult Central Nervous System Molecular Therapy. 24: S99. DOI: 10.1016/S1525-0016(16)33061-1 |
0.396 |
|
| 2016 |
Rice AJ, Bedbrook CN, Yang KK, Gradinaru V, Arnold FH. Rhodopsin Engineering through Structure-Guided Recombination Biophysical Journal. 110: 170a. DOI: 10.1016/J.Bpj.2015.11.947 |
0.337 |
|
| 2016 |
Gradinaru V. Tools for Anatomical and Functional Analysis of Widely Distributed Brain Networks Biophysical Journal. 110: 364a-365a. DOI: 10.1016/J.BPJ.2015.11.1965 |
0.395 |
|
| 2014 |
Yang B, Treweek JB, Kulkarni RP, Deverman BE, Chen CK, Lubeck E, Shah S, Cai L, Gradinaru V. Single-cell phenotyping within transparent intact tissue through whole-body clearing. Cell. 158: 945-58. PMID 25088144 DOI: 10.1016/J.Cell.2014.07.017 |
0.304 |
|
| 2014 |
Birmingham K, Gradinaru V, Anikeeva P, Grill WM, Pikov V, McLaughlin B, Pasricha P, Weber D, Ludwig K, Famm K. Bioelectronic medicines: a research roadmap. Nature Reviews. Drug Discovery. 13: 399-400. PMID 24875080 DOI: 10.1038/Nrd4351 |
0.568 |
|
| 2014 |
Deisseroth K, Gradinaru V. Advances in Neurotechniques: Methods that Reveal the Structure and Function of the Brain Science. 345: 698.3-698. DOI: 10.1126/science.345.6197.698-c |
0.542 |
|
| 2013 |
Sukhotinsky I, Chan AM, Ahmed OJ, Rao VR, Gradinaru V, Ramakrishnan C, Deisseroth K, Majewska AK, Cash SS. Optogenetic delay of status epilepticus onset in an in vivo rodent epilepsy model. Plos One. 8: e62013. PMID 23637949 DOI: 10.1371/Journal.Pone.0062013 |
0.481 |
|
| 2013 |
Chung K, Wallace J, Kim SY, Kalyanasundaram S, Andalman AS, Davidson TJ, Mirzabekov JJ, Zalocusky KA, Mattis J, Denisin AK, Pak S, Bernstein H, Ramakrishnan C, Grosenick L, Gradinaru V, et al. Structural and molecular interrogation of intact biological systems. Nature. 497: 332-7. PMID 23575631 DOI: 10.1038/Nature12107 |
0.742 |
|
| 2012 |
Mattis J, Tye KM, Ferenczi EA, Ramakrishnan C, O'Shea DJ, Prakash R, Gunaydin LA, Hyun M, Fenno LE, Gradinaru V, Yizhar O, Deisseroth K. Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins. Nature Methods. 9: 159-72. PMID 22179551 DOI: 10.1038/Nmeth.1808 |
0.742 |
|
| 2011 |
Domingos AI, Vaynshteyn J, Voss HU, Ren X, Gradinaru V, Zang F, Deisseroth K, de Araujo IE, Friedman J. Leptin regulates the reward value of nutrient. Nature Neuroscience. 14: 1562-8. PMID 22081158 DOI: 10.1038/nn.2977 |
0.489 |
|
| 2011 |
Goshen I, Brodsky M, Prakash R, Wallace J, Gradinaru V, Ramakrishnan C, Deisseroth K. Dynamics of retrieval strategies for remote memories. Cell. 147: 678-89. PMID 22019004 DOI: 10.1016/J.Cell.2011.09.033 |
0.442 |
|
| 2011 |
Tye KM, Prakash R, Kim SY, Fenno LE, Grosenick L, Zarabi H, Thompson KR, Gradinaru V, Ramakrishnan C, Deisseroth K. Amygdala circuitry mediating reversible and bidirectional control of anxiety. Nature. 471: 358-62. PMID 21389985 DOI: 10.1038/Nature09820 |
0.768 |
|
| 2010 |
Witten IB, Lin SC, Brodsky M, Prakash R, Diester I, Anikeeva P, Gradinaru V, Ramakrishnan C, Deisseroth K. Cholinergic interneurons control local circuit activity and cocaine conditioning. Science (New York, N.Y.). 330: 1677-81. PMID 21164015 DOI: 10.1126/Science.1193771 |
0.773 |
|
| 2010 |
Lee JH, Durand R, Gradinaru V, Zhang F, Goshen I, Kim DS, Fenno LE, Ramakrishnan C, Deisseroth K. Global and local fMRI signals driven by neurons defined optogenetically by type and wiring. Nature. 465: 788-92. PMID 20473285 DOI: 10.1038/Nature09108 |
0.742 |
|
| 2010 |
Gradinaru V, Zhang F, Ramakrishnan C, Mattis J, Prakash R, Diester I, Goshen I, Thompson KR, Deisseroth K. Molecular and cellular approaches for diversifying and extending optogenetics. Cell. 141: 154-65. PMID 20303157 DOI: 10.1016/J.Cell.2010.02.037 |
0.78 |
|
| 2010 |
Zhang F, Gradinaru V, Adamantidis AR, Durand R, Airan RD, de Lecea L, Deisseroth K. Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures. Nature Protocols. 5: 439-56. PMID 20203662 DOI: 10.1038/Nprot.2009.226 |
0.758 |
|
| 2010 |
Lee JH, Durand R, Gradinaru V, Zhang F, Goshen I, Kim DS, Fenno LE, Ramakrishnan C, Deisseroth K. Lee et al. reply Nature. 468: E4-E5. DOI: 10.1038/Nature09533 |
0.726 |
|
| 2009 |
Gradinaru V, Mogri M, Thompson KR, Henderson JM, Deisseroth K. Optical deconstruction of parkinsonian neural circuitry. Science (New York, N.Y.). 324: 354-9. PMID 19299587 DOI: 10.1126/Science.1167093 |
0.789 |
|
| 2008 |
Gradinaru V, Thompson KR, Deisseroth K. eNpHR: a Natronomonas halorhodopsin enhanced for optogenetic applications. Brain Cell Biology. 36: 129-39. PMID 18677566 DOI: 10.1007/s11068-008-9027-6 |
0.521 |
|
| 2008 |
Schneider MB, Gradinaru V, Zhang F, Deisseroth K. Controlling neuronal activity. The American Journal of Psychiatry. 165: 562. PMID 18450936 DOI: 10.1176/Appi.Ajp.2008.08030444 |
0.573 |
|
| 2007 |
Gradinaru V, Thompson KR, Zhang F, Mogri M, Kay K, Schneider MB, Deisseroth K. Targeting and readout strategies for fast optical neural control in vitro and in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 14231-8. PMID 18160630 DOI: 10.1523/Jneurosci.3578-07.2007 |
0.762 |
|
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