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William C. Mobley

Affiliations: 
Neurology University of California, San Diego, La Jolla, CA 
Area:
neurodegneration, Down syndrome
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"William Mobley"
Bio:

William C. Mobley, MD, PhD is a clinician and researcher who is internationally known for his work on degenerative diseases of the central nervous system and the neurobiology of Down syndrome.

Mean distance: 15.07 (cluster 40)
 
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Parents

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Eric M. Shooter grad student Stanford Medical School/Palo Alto VA

Children

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Charles L. Howe grad student 2000 UCSF
April M. Weissmiller grad student 2013 UCSD
David M. Holtzman post-doc UCSF
Ahmad Salehi post-doc Stanford Medical School/Palo Alto VA

Collaborators

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Ahmad Salehi collaborator 1999-2010 Stanford Medical School/Palo Alto VA
BETA: Related publications

Publications

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Sawa M, Overk C, Becker A, et al. (2021) Impact of increased APP gene dose in Down syndrome and the Dp16 mouse model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Chen XQ, Salehi A, Pearn ML, et al. (2020) Targeting increased levels of APP in Down syndrome: Posiphen-mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Johnstone A, Mobley W. (2020) Local TrkB signaling: themes in development and neural plasticity. Cell and Tissue Research. 382: 101-111
Qian H, Kang X, Hu J, et al. (2020) Author Correction: Reversing a model of Parkinson's disease with in situ converted nigral neurons. Nature
Stupack J, Xiong XP, Jiang LL, et al. (2020) Soluble SORLA enhances neurite outgrowth and regeneration through activation of the EGF Receptor/ERK signaling axis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience
Qian H, Kang X, Hu J, et al. (2020) Reversing a model of Parkinson's disease with in situ converted nigral neurons. Nature. 582: 550-556
Snyder HM, Bain LJ, Brickman AM, et al. (2020) Further understanding the connection between Alzheimer's disease and Down syndrome. Alzheimer's & Dementia : the Journal of the Alzheimer's Association
Kaplan DR, Mobley WC. (2020) (H)Elping nerve growth factor: Elp1 inhibits TrkA's phosphatase to maintain retrograde signaling. The Journal of Clinical Investigation
Decourt B, Mobley W, Reiman E, et al. (2020) Recent Perspectives on APP, Secretases, Endosomal Pathways and How they Influence Alzheimer's Related Pathological Changes in Down Syndrome. Journal of Alzheimer's Disease & Parkinsonism. 002
Chen XQ, Mobley WC. (2019) Alzheimer Disease Pathogenesis: Insights From Molecular and Cellular Biology Studies of Oligomeric Aβ and Tau Species. Frontiers in Neuroscience. 13: 659
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