Year |
Citation |
Score |
2020 |
Walsh MB, Janzen E, Wingrove E, Hosseinibarkooie S, Muela NR, Davidow L, Dimitriadi M, Norabuena EM, Rubin LL, Wirth B, Hart AC. Genetic modifiers ameliorate endocytic and neuromuscular defects in a model of spinal muscular atrophy. Bmc Biology. 18: 127. PMID 32938453 DOI: 10.1186/s12915-020-00845-w |
0.36 |
|
2020 |
Schuch KN, Govindarajan LN, Guo Y, Baskoylu SN, Kim S, Kimia B, Serre T, Hart AC. Discriminating between sleep and exercise-induced fatigue using computer vision and behavioral genetics. Journal of Neurogenetics. 1-13. PMID 32811254 DOI: 10.1080/01677063.2020.1804565 |
0.393 |
|
2019 |
Carskadon MA, Chappell KR, Barker DH, Hart AC, Dwyer K, Gredvig-Ardito C, Starr C, McGeary JE. A pilot prospective study of sleep patterns and DNA methylation-characterized epigenetic aging in young adults. Bmc Research Notes. 12: 583. PMID 31526398 DOI: 10.1186/S13104-019-4633-1 |
0.302 |
|
2019 |
Carskadon MA, Chappell KR, Barker DH, Hart AC, Dwyer K, Gredvig-Ardito C, McGeary JE. 0022 Prospective Assessment of Sleep and Epigenetic Aging: Preliminary Findings Sleep. 42: A9-A9. DOI: 10.1093/Sleep/Zsz067.021 |
0.338 |
|
2018 |
Huang H, Hayden DJ, Zhu CT, Bennett HL, Venkatachalam V, Skuja LL, Hart AC. Gap Junctions and NCA Cation Channels Are Critical for Developmentally-Timed Sleep and Arousal in . Genetics. PMID 30323068 DOI: 10.1534/Genetics.118.301551 |
0.714 |
|
2018 |
Baskoylu SN, Yersak J, O'Hern P, Grosser S, Simon J, Kim S, Schuch K, Dimitriadi M, Yanagi KS, Lins J, Hart AC. Single copy/knock-in models of ALS SOD1 in C. elegans suggest loss and gain of function have different contributions to cholinergic and glutamatergic neurodegeneration. Plos Genetics. 14: e1007682. PMID 30296255 DOI: 10.1371/journal.pgen.1007682 |
0.332 |
|
2018 |
Sorkaç A, DiIorio MA, O'Hern PJ, Baskoylu SN, Graham HK, Hart AC. LIN-12/Notch Regulates GABA Signaling at the Neuromuscular Junction. G3 (Bethesda, Md.). PMID 29950427 DOI: 10.1534/g3.118.200202 |
0.323 |
|
2018 |
Bennett HL, Khoruzhik Y, Hayden D, Huang H, Sanders J, Walsh MB, Biron D, Hart AC. Normal sleep bouts are not essential for C. elegans survival and FoxO is important for compensatory changes in sleep. Bmc Neuroscience. 19: 10. PMID 29523076 DOI: 10.1186/S12868-018-0408-1 |
0.389 |
|
2017 |
Huang H, Zhu CT, Skuja LL, Hayden DJ, Hart AC. Genome-Wide Screen for Genes Involved in Caenorhabditis elegans Developmentally Timed Sleep. G3 (Bethesda, Md.). PMID 28743807 DOI: 10.1534/G3.117.300071 |
0.719 |
|
2017 |
O'Hern PJ, do Carmo G Gonçalves I, Brecht J, López Soto EJ, Simon J, Chapkis N, Lipscombe D, Kye MJ, Hart AC. Decreased microRNA levels lead to deleterious increases in neuronal M2 muscarinic receptors in Spinal Muscular Atrophy models. Elife. 6. PMID 28463115 DOI: 10.7554/eLife.20752 |
0.358 |
|
2017 |
Huang H, Zhu Y, Eliot MN, Knopik VS, McGeary JE, Carskadon MA, Hart AC. Combining Human Epigenetics and Sleep Studies in C. elegans: A Cross-species Approach for Finding Conserved Genes Regulating Sleep. Sleep. PMID 28431118 DOI: 10.1093/Sleep/Zsx063 |
0.386 |
|
2017 |
Riessland M, Kaczmarek A, Schneider S, Swoboda KJ, Löhr H, Bradler C, Grysko V, Dimitriadi M, Hosseinibarkooie S, Torres-Benito L, Peters M, Upadhyay A, Biglari N, Kröber S, Hölker I, ... ... Hart AC, et al. Neurocalcin Delta Suppression Protects against Spinal Muscular Atrophy in Humans and across Species by Restoring Impaired Endocytosis. American Journal of Human Genetics. PMID 28132687 DOI: 10.1016/J.Ajhg.2017.01.005 |
0.381 |
|
2016 |
Sorkaç A, Alcantara IC, Hart AC. In Vivo Modelling of ATP1A3 G316S-Induced Ataxia in C. elegans Using CRISPR/Cas9-Mediated Homologous Recombination Reveals Dominant Loss of Function Defects. Plos One. 11: e0167963. PMID 27936181 DOI: 10.1371/Journal.Pone.0167963 |
0.731 |
|
2016 |
Dimitriadi M, Derdowski A, Kalloo G, Maginnis MS, O'Hern P, Bliska B, Sorkaç A, Nguyen KC, Cook SJ, Poulogiannis G, Atwood WJ, Hall DH, Hart AC. Decreased function of survival motor neuron protein impairs endocytic pathways. Proceedings of the National Academy of Sciences of the United States of America. PMID 27402754 DOI: 10.1073/Pnas.1600015113 |
0.375 |
|
2016 |
Fry AL, Laboy JT, Huang H, Hart AC, Norman KR. A Conserved GEF for Rho-Family GTPases Acts in an EGF Signaling Pathway to Promote Sleep-Like Quiescence in Caenorhabditis elegans. Genetics. PMID 26801183 DOI: 10.1534/Genetics.115.183038 |
0.41 |
|
2014 |
Singh K, Ju JY, Walsh MB, DiIorio MA, Hart AC. Deep conservation of genes required for both Drosphila melanogaster and Caenorhabditis elegans sleep includes a role for dopaminergic signaling. Sleep. 37: 1439-51. PMID 25142568 DOI: 10.5665/sleep.3990 |
0.394 |
|
2013 |
Sen A, Dimlich DN, Guruharsha KG, Kankel MW, Hori K, Yokokura T, Brachat S, Richardson D, Loureiro J, Sivasankaran R, Curtis D, Davidow LS, Rubin LL, Hart AC, Van Vactor D, et al. Genetic circuitry of Survival motor neuron, the gene underlying spinal muscular atrophy. Proceedings of the National Academy of Sciences of the United States of America. 110: E2371-80. PMID 23757500 DOI: 10.1073/Pnas.1301738110 |
0.635 |
|
2013 |
Kwon DY, Dimitriadi M, Terzic B, Cable C, Hart AC, Chitnis A, Fischbeck KH, Burnett BG. The E3 ubiquitin ligase mind bomb 1 ubiquitinates and promotes the degradation of survival of motor neuron protein. Molecular Biology of the Cell. 24: 1863-71. PMID 23615451 DOI: 10.1091/Mbc.E13-01-0042 |
0.34 |
|
2013 |
Dimitriadi M, Kye MJ, Kalloo G, Yersak JM, Sahin M, Hart AC. The neuroprotective drug riluzole acts via small conductance Ca2+-activated K+ channels to ameliorate defects in spinal muscular atrophy models. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 6557-62. PMID 23575853 DOI: 10.1523/Jneurosci.1536-12.2013 |
0.353 |
|
2013 |
Singh K, Huang H, Hart AC. Do C. elegans sleep? A closer look. Sleep. 36: 307-8. PMID 23450901 DOI: 10.5665/Sleep.2436 |
0.372 |
|
2011 |
Liu-Yesucevitz L, Bassell GJ, Gitler AD, Hart AC, Klann E, Richter JD, Warren ST, Wolozin B. Local RNA translation at the synapse and in disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16086-93. PMID 22072660 DOI: 10.1523/Jneurosci.4105-11.2011 |
0.357 |
|
2011 |
Singh K, Chao MY, Somers GA, Komatsu H, Corkins ME, Larkins-Ford J, Tucey T, Dionne HM, Walsh MB, Beaumont EK, Hart DP, Lockery SR, Hart AC. C. elegans Notch signaling regulates adult chemosensory response and larval molting quiescence. Current Biology : Cb. 21: 825-34. PMID 21549604 DOI: 10.1016/j.cub.2011.04.010 |
0.339 |
|
2011 |
Hyde R, Corkins ME, Somers GA, Hart AC. PKC-1 acts with the ERK MAPK signaling pathway to regulate Caenorhabditis elegans mechanosensory response. Genes, Brain, and Behavior. 10: 286-98. PMID 21143768 DOI: 10.1111/j.1601-183X.2010.00667.x |
0.38 |
|
2010 |
Dimitriadi M, Sleigh JN, Walker A, Chang HC, Sen A, Kalloo G, Harris J, Barsby T, Walsh MB, Satterlee JS, Li C, Van Vactor D, Artavanis-Tsakonas S, Hart AC. Conserved genes act as modifiers of invertebrate SMN loss of function defects. Plos Genetics. 6: e1001172. PMID 21124729 DOI: 10.1371/Journal.Pgen.1001172 |
0.64 |
|
2010 |
Haspel G, O'Donovan MJ, Hart AC. Motoneurons dedicated to either forward or backward locomotion in the nematode Caenorhabditis elegans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11151-6. PMID 20720122 DOI: 10.1523/Jneurosci.2244-10.2010 |
0.705 |
|
2010 |
Dimitriadi M, Hart AC. Neurodegenerative disorders: insights from the nematode Caenorhabditis elegans. Neurobiology of Disease. 40: 4-11. PMID 20493260 DOI: 10.1016/j.nbd.2010.05.012 |
0.351 |
|
2009 |
Guo ZV, Hart AC, Ramanathan S. Optical interrogation of neural circuits in Caenorhabditis elegans. Nature Methods. 6: 891-6. PMID 19898486 DOI: 10.1038/Nmeth.1397 |
0.324 |
|
2009 |
Jeong H, Then F, Melia TJ, Mazzulli JR, Cui L, Savas JN, Voisine C, Paganetti P, Tanese N, Hart AC, Yamamoto A, Krainc D. Acetylation targets mutant huntingtin to autophagosomes for degradation. Cell. 137: 60-72. PMID 19345187 DOI: 10.1016/J.Cell.2009.03.018 |
0.353 |
|
2008 |
Chang HC, Dimlich DN, Yokokura T, Mukherjee A, Kankel MW, Sen A, Sridhar V, Fulga TA, Hart AC, Van Vactor D, Artavanis-Tsakonas S. Modeling spinal muscular atrophy in Drosophila. Plos One. 3: e3209. PMID 18791638 DOI: 10.1371/Journal.Pone.0003209 |
0.662 |
|
2008 |
Komatsu H, Chao MY, Larkins-Ford J, Corkins ME, Somers GA, Tucey T, Dionne HM, White JQ, Wani K, Boxem M, Hart AC. OSM-11 facilitates LIN-12 Notch signaling during Caenorhabditis elegans vulval development. Plos Biology. 6: e196. PMID 18700817 DOI: 10.1371/journal.pbio.0060196 |
0.386 |
|
2007 |
Varma H, Cheng R, Voisine C, Hart AC, Stockwell BR. Inhibitors of metabolism rescue cell death in Huntington's disease models. Proceedings of the National Academy of Sciences of the United States of America. 104: 14525-30. PMID 17726098 DOI: 10.1073/Pnas.0704482104 |
0.336 |
|
2007 |
Ferkey DM, Hyde R, Haspel G, Dionne HM, Hess HA, Suzuki H, Schafer WR, Koelle MR, Hart AC. C. elegans G protein regulator RGS-3 controls sensitivity to sensory stimuli. Neuron. 53: 39-52. PMID 17196529 DOI: 10.1016/J.Neuron.2006.11.015 |
0.696 |
|
2007 |
Jia K, Hart AC, Levine B. Autophagy genes protect against disease caused by polyglutamine expansion proteins in Caenorhabditis elegans. Autophagy. 3: 21-5. PMID 17172799 DOI: 10.4161/Auto.3528 |
0.364 |
|
2006 |
Carre-Pierrat M, Baillie D, Johnsen R, Hyde R, Hart A, Granger L, Ségalat L. Characterization of the Caenorhabditis elegans G protein-coupled serotonin receptors. Invertebrate Neuroscience : In. 6: 189-205. PMID 17082916 DOI: 10.1007/S10158-006-0033-Z |
0.307 |
|
2006 |
Yang F, Vought BW, Satterlee JS, Walker AK, Jim Sun ZY, Watts JL, DeBeaumont R, Saito RM, Hyberts SG, Yang S, Macol C, Iyer L, Tjian R, van den Heuvel S, Hart AC, et al. An ARC/Mediator subunit required for SREBP control of cholesterol and lipid homeostasis. Nature. 442: 700-4. PMID 16799563 DOI: 10.1038/Nature04942 |
0.31 |
|
2006 |
Bates EA, Victor M, Jones AK, Shi Y, Hart AC. Differential contributions of Caenorhabditis elegans histone deacetylases to huntingtin polyglutamine toxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2830-8. PMID 16525063 DOI: 10.1523/Jneurosci.3344-05.2006 |
0.368 |
|
2005 |
Chao MY, Larkins-Ford J, Tucey TM, Hart AC. lin-12 Notch functions in the adult nervous system of C. elegans. Bmc Neuroscience. 6: 45. PMID 16011804 DOI: 10.1186/1471-2202-6-45 |
0.345 |
|
2004 |
Voisine C, Hart AC. Caenorhabditis elegans as a model system for triplet repeat diseases. Methods in Molecular Biology (Clifton, N.J.). 277: 141-60. PMID 15201454 DOI: 10.1385/1-59259-804-8:141 |
0.356 |
|
2004 |
Fukuto HS, Ferkey DM, Apicella AJ, Lans H, Sharmeen T, Chen W, Lefkowitz RJ, Jansen G, Schafer WR, Hart AC. G protein-coupled receptor kinase function is essential for chemosensation in C. elegans. Neuron. 42: 581-93. PMID 15157420 DOI: 10.1016/S0896-6273(04)00252-1 |
0.375 |
|
2002 |
Faber PW, Voisine C, King DC, Bates EA, Hart AC. Glutamine/proline-rich PQE-1 proteins protect Caenorhabditis elegans neurons from huntingtin polyglutamine neurotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 99: 17131-6. PMID 12486229 DOI: 10.1073/Pnas.262544899 |
0.391 |
|
2001 |
Nathoo AN, Moeller RA, Westlund BA, Hart AC. Identification of neuropeptide-like protein gene families in Caenorhabditiselegans and other species. Proceedings of the National Academy of Sciences of the United States of America. 98: 14000-5. PMID 11717458 DOI: 10.1073/pnas.241231298 |
0.34 |
|
1999 |
Li C, Nelson LS, Kim K, Nathoo A, Hart AC. Neuropeptide gene families in the nematode Caenorhabditis elegans. Annals of the New York Academy of Sciences. 897: 239-52. PMID 10676452 DOI: 10.1111/j.1749-6632.1999.tb07895.x |
0.322 |
|
1999 |
Hart AC, Kass J, Shapiro JE, Kaplan JM. Distinct signaling pathways mediate touch and osmosensory responses in a polymodal sensory neuron. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 1952-8. PMID 10066248 DOI: 10.1523/Jneurosci.19-06-01952.1999 |
0.366 |
|
1999 |
Faber PW, Alter JR, MacDonald ME, Hart AC. Polyglutamine-mediated dysfunction and apoptotic death of a Caenorhabditis elegans sensory neuron. Proceedings of the National Academy of Sciences of the United States of America. 96: 179-84. PMID 9874792 DOI: 10.1073/Pnas.96.1.179 |
0.34 |
|
1999 |
Hart AC. Chapter 3.3.6 Forward genetic approaches in the analysis of Caenorhabditis elegans Techniques in the Behavioral and Neural Sciences. 13: 569-584. DOI: 10.1016/S0921-0709(99)80045-5 |
0.309 |
|
1998 |
Serra-Pagès C, Medley QG, Tang M, Hart A, Streuli M. Liptins, a family of LAR transmembrane protein-tyrosine phosphatase- interacting proteins Journal of Biological Chemistry. 273: 15611-15620. PMID 9624153 DOI: 10.1074/jbc.273.25.15611 |
0.307 |
|
1998 |
Berger AJ, Hart AC, Kaplan JM. Gαs-Induced Neurodegeneration inCaenorhabditis elegans The Journal of Neuroscience. 18: 2871-2880. DOI: 10.1523/Jneurosci.18-08-02871.1998 |
0.361 |
|
1995 |
Hart AC, Sims S, Kaplan JM. Synaptic code for sensory modalities revealed by C. elegans GLR-1 glutamate receptor. Nature. 378: 82-5. PMID 7477294 DOI: 10.1038/378082A0 |
0.308 |
|
1993 |
Hart AC, Harrison SD, Van Vactor DL, Rubin GM, Zipursky SL. The interaction of bride of sevenless with sevenless is conserved between Drosophila virilis and Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. 90: 5047-51. PMID 8506350 DOI: 10.1073/Pnas.90.11.5047 |
0.691 |
|
1993 |
Hart AC, Krämer H, Zipursky SL. Extracellular domain of the boss transmembrane ligand acts as an antagonist of the sev receptor. Nature. 361: 732-6. PMID 7680109 DOI: 10.1038/361732a0 |
0.578 |
|
1992 |
Zipursky SL, Krämer H, Cagan R, Hart A, Vactor DV. Induction of the R7 neuron in the Drosophila compound eye: the bride of sevenless and sevenless interaction. Cold Spring Harbor Symposia On Quantitative Biology. 57: 381-9. PMID 1339673 DOI: 10.1101/Sqb.1992.057.01.043 |
0.629 |
|
1992 |
Cagan RL, Krämer H, Hart AC, Zipursky SL. The bride of sevenless and sevenless interaction: internalization of a transmembrane ligand. Cell. 69: 393-9. PMID 1316239 DOI: 10.1016/0092-8674(92)90442-F |
0.651 |
|
1990 |
Hart AC, Krämer H, Van Vactor DL, Paidhungat M, Zipursky SL. Induction of cell fate in the Drosophila retina: the bride of sevenless protein is predicted to contain a large extracellular domain and seven transmembrane segments. Genes & Development. 4: 1835-47. PMID 2276620 |
0.705 |
|
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