Year |
Citation |
Score |
2024 |
Chakraborty P, Ibáñez de Opakua A, Purslow JA, Fromm SA, Chatterjee D, Zachrdla M, Zhuang S, Puri S, Wolozin B, Zweckstetter M. GSK3β phosphorylation catalyzes the aggregation of tau into Alzheimer's disease-like filaments. Proceedings of the National Academy of Sciences of the United States of America. 121: e2414176121. PMID 39693350 DOI: 10.1073/pnas.2414176121 |
0.303 |
|
2024 |
Jiang L, Roberts R, Wong M, Zhang L, Webber CJ, Libera J, Wang Z, Kilci A, Jenkins M, Ortiz AR, Dorrian L, Sun J, Sun G, Rashad S, Kornbrek C, ... ... Wolozin B, et al. β-amyloid accumulation enhances microtubule associated protein tau pathology in an APP/MAPT mouse model of Alzheimer's disease. Frontiers in Neuroscience. 18: 1372297. PMID 38572146 DOI: 10.3389/fnins.2024.1372297 |
0.321 |
|
2021 |
Jiang L, Lin W, Zhang C, Ash PEA, Verma M, Kwan J, van Vliet E, Yang Z, Cruz AL, Boudeau S, Maziuk BF, Lei S, Song J, Alvarez VE, Hovde S, ... ... Wolozin B, et al. Interaction of tau with HNRNPA2B1 and N-methyladenosine RNA mediates the progression of tauopathy. Molecular Cell. PMID 34453888 DOI: 10.1016/j.molcel.2021.07.038 |
0.301 |
|
2020 |
Webber CJ, Lei SE, Wolozin B. The pathophysiology of neurodegenerative disease: Disturbing the balance between phase separation and irreversible aggregation. Progress in Molecular Biology and Translational Science. 174: 187-223. PMID 32828466 DOI: 10.1016/Bs.Pmbts.2020.04.021 |
0.404 |
|
2020 |
Reiss AB, Glass AD, Wisniewski T, Wolozin B, Gomolin IH, Pinkhasov A, De Leon J, Stecker MM. Alzheimer's disease: many failed trials, so where do we go from here? Journal of Investigative Medicine : the Official Publication of the American Federation For Clinical Research. 68: 1135-1140. PMID 32699179 DOI: 10.1136/Jim-2020-001297 |
0.392 |
|
2020 |
LeBlang CJ, Medalla M, Nicoletti NW, Hays EC, Zhao J, Shattuck J, Cruz AL, Wolozin B, Luebke JI. Reduction of the RNA Binding Protein TIA1 Exacerbates Neuroinflammation in Tauopathy. Frontiers in Neuroscience. 14: 285. PMID 32327969 DOI: 10.3389/Fnins.2020.00285 |
0.396 |
|
2020 |
Pourhaghighi R, Ash PEA, Phanse S, Goebels F, Hu LZM, Chen S, Zhang Y, Wierbowski SD, Boudeau S, Moutaoufik MT, Malty RH, Malolepsza E, Tsafou K, Nathan A, Cromar G, ... ... Wolozin B, et al. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Systems. 10: 333-350.e14. PMID 32325033 DOI: 10.1016/J.Cels.2020.03.003 |
0.314 |
|
2020 |
Li M, Reisman J, Morris-Eppolito B, Qian SX, Kazis LE, Wolozin B, Goldstein LE, Xia W. Beneficial association of angiotensin-converting enzyme inhibitors and statins on the occurrence of possible Alzheimer's disease after traumatic brain injury. Alzheimer's Research & Therapy. 12: 33. PMID 32220235 DOI: 10.1186/S13195-020-00589-3 |
0.338 |
|
2019 |
Cruz A, Verma M, Wolozin B. The Pathophysiology of Tau and Stress Granules in Disease. Advances in Experimental Medicine and Biology. 1184: 359-372. PMID 32096049 DOI: 10.1007/978-981-32-9358-8_26 |
0.376 |
|
2019 |
Apicco DJ, Zhang C, Maziuk B, Jiang L, Ballance HI, Boudeau S, Ung C, Li H, Wolozin B. Dysregulation of RNA Splicing in Tauopathies. Cell Reports. 29: 4377-4388.e4. PMID 31875547 DOI: 10.1016/J.Celrep.2019.11.093 |
0.371 |
|
2019 |
Wolozin B, Ivanov P. Stress granules and neurodegeneration Nature Reviews Neuroscience. 20: 649-666. PMID 31582840 DOI: 10.1038/S41583-019-0222-5 |
0.398 |
|
2019 |
Gan Q, Yao H, Na H, Ballance H, Tao Q, Leung L, Tian H, Zhu H, Wolozin B, Qiu WQ. Effects of Amylin Against Amyloid-β-Induced Tauopathy and Synapse Loss in Primary Neurons. Journal of Alzheimer's Disease : Jad. PMID 31306122 DOI: 10.3233/Jad-190161 |
0.369 |
|
2019 |
Wolozin B. The Evolution of Phase-Separated TDP-43 in Stress. Neuron. 102: 265-267. PMID 30998893 DOI: 10.1016/J.Neuron.2019.03.041 |
0.305 |
|
2019 |
Sotiropoulos I, Silva J, Rodrigues S, Gomes P, Dioli C, Soares-Cunha C, Takashima A, Wolozin B, Sousa N. Novel Insights Of Tau Rna-Protein Biology In The Precipitating Role Of Chronic Stress On Alzheimer’S Disease Brain Pathology Alzheimers & Dementia. 15: 1643. DOI: 10.1016/J.Jalz.2019.06.4892 |
0.381 |
|
2018 |
Jiang L, Ash PEA, Maziuk BF, Ballance HI, Boudeau S, Abdullatif AA, Orlando M, Petrucelli L, Ikezu T, Wolozin B. TIA1 regulates the generation and response to toxic tau oligomers. Acta Neuropathologica. PMID 30465259 DOI: 10.1007/S00401-018-1937-5 |
0.402 |
|
2018 |
Silva JM, Rodrigues S, Sampaio-Marques B, Gomes P, Neves-Carvalho A, Dioli C, Soares-Cunha C, Mazuik BF, Takashima A, Ludovico P, Wolozin B, Sousa N, Sotiropoulos I. Dysregulation of autophagy and stress granule-related proteins in stress-driven Tau pathology. Cell Death and Differentiation. PMID 30442948 DOI: 10.1038/S41418-018-0217-1 |
0.422 |
|
2018 |
Maziuk BF, Apicco DJ, Cruz AL, Jiang L, Ash PEA, da Rocha EL, Zhang C, Yu WH, Leszyk J, Abisambra JF, Li H, Wolozin B. RNA binding proteins co-localize with small tau inclusions in tauopathy. Acta Neuropathologica Communications. 6: 71. PMID 30068389 DOI: 10.1186/S40478-018-0574-5 |
0.431 |
|
2018 |
Apicco DJ, Ash PEA, Maziuk B, LeBlang C, Medalla M, Al Abdullatif A, Ferragud A, Botelho E, Ballance HI, Dhawan U, Boudeau S, Cruz AL, Kashy D, Wong A, Goldberg LR, ... ... Wolozin B, et al. Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo. Nature Neuroscience. 21: 72-80. PMID 29273772 DOI: 10.1038/S41593-017-0022-Z |
0.411 |
|
2017 |
Maziuk B, Ballance HI, Wolozin B. Dysregulation of RNA Binding Protein Aggregation in Neurodegenerative Disorders. Frontiers in Molecular Neuroscience. 10: 89. PMID 28420962 DOI: 10.3389/Fnmol.2017.00089 |
0.431 |
|
2017 |
Zhu H, Xue X, Wang E, Wallack M, Na H, Hooker JM, Kowall N, Tao Q, Stein TD, Wolozin B, Qiu WQ. Amylin receptor ligands reduce the pathological cascade of Alzheimer's disease. Neuropharmacology. PMID 28363773 DOI: 10.1016/J.Neuropharm.2017.03.030 |
0.389 |
|
2017 |
Wolozin B, Apicco DJ, Zhang C, Ash PEA, Maziuk B, Abdullatif AA, Ballance H, Goldberg LR, Yazdani N, Ung C, Kanaan NM, Ikezu T, Bryant CD, Li H. Tau-Induced Neurodegeneration Is Mediated By Rna Binding Proteins Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.07.157 |
0.346 |
|
2016 |
Kuwahara T, Inoue K, D'Agati VD, Fujimoto T, Eguchi T, Saha S, Wolozin B, Iwatsubo T, Abeliovich A. LRRK2 and RAB7L1 coordinately regulate axonal morphology and lysosome integrity in diverse cellular contexts. Scientific Reports. 6: 29945. PMID 27424887 DOI: 10.1038/Srep29945 |
0.35 |
|
2016 |
Ostrowski SM, Johnson K, Siefert M, Shank S, Sironi L, Wolozin B, Landreth GE, Ziady AG. Simvastatin inhibits protein isoprenylation in the brain. Neuroscience. PMID 27180285 DOI: 10.1016/J.Neuroscience.2016.04.053 |
0.373 |
|
2016 |
Vanderweyde T, Apicco DJ, Youmans-Kidder K, Ash PE, Cook C, Lummertz da Rocha E, Jansen-West K, Frame AA, Citro A, Leszyk JD, Ivanov P, Abisambra JF, Steffen M, Li H, Petrucelli L, ... Wolozin B, et al. Interaction of tau with the RNA-binding Protein TIA1 Regulates tau Pathophysiology and Toxicity. Cell Reports. PMID 27160897 DOI: 10.1016/J.Celrep.2016.04.045 |
0.409 |
|
2016 |
Meier S, Bell M, Lyons DN, Rodriguez-Rivera J, Ingram A, Fontaine SN, Mechas E, Chen J, Wolozin B, LeVine H, Zhu H, Abisambra JF. Pathological Tau Promotes Neuronal Damage by Impairing Ribosomal Function and Decreasing Protein Synthesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 1001-7. PMID 26791227 DOI: 10.1523/Jneurosci.3029-15.2016 |
0.418 |
|
2016 |
Zhou Q, Yen A, Rymarczyk G, Asai H, Trengrove C, Aziz N, Kirber MT, Mostoslavsky G, Ikezu T, Wolozin B, Bolotina VM. Impairment of PARK14-dependent Ca(2+) signalling is a novel determinant of Parkinson's disease. Nature Communications. 7: 10332. PMID 26755131 DOI: 10.1038/Ncomms10332 |
0.328 |
|
2016 |
Ikezu T, Ikezu S, Varnum M, Wolozin B, Butovsky O, Kügler S, Medalla M, Luebke J, Haydar TF. O4-04-01: Microglial Exosomes Propagate Tau Protein from the Entorhinal Cortex to the Hippocampus: An Early Pathophysiology of Alzheimer's Disease Alzheimer's & Dementia. 12: P339-P340. DOI: 10.1016/J.Jalz.2016.06.624 |
0.375 |
|
2016 |
Sotiropoulos I, Rodrigues S, Silva J, Wolozin B, Sousa N. P4-081: Environmental Stress and Glucocorticoids Trigger an HDAC6-Dependent Induction of Stress Granules and TAU Aggregation: Implications For Alzheimer's Disease Alzheimer's & Dementia. 12: P1044-P1044. DOI: 10.1016/J.Jalz.2016.06.2170 |
0.368 |
|
2015 |
Wolozin B, Ikezu T. Syk and Yea Shall Find. Ebiomedicine. 2: 1590-1. PMID 26870779 DOI: 10.1016/J.Ebiom.2015.11.012 |
0.451 |
|
2015 |
Asai H, Ikezu S, Tsunoda S, Medalla M, Luebke J, Haydar T, Wolozin B, Butovsky O, Kügler S, Ikezu T. Depletion of microglia and inhibition of exosome synthesis halt tau propagation. Nature Neuroscience. 18: 1584-93. PMID 26436904 DOI: 10.1038/Nn.4132 |
0.412 |
|
2015 |
Saha S, Ash PE, Gowda V, Liu L, Shirihai O, Wolozin B. Mutations in LRRK2 potentiate age-related impairment of autophagic flux. Molecular Neurodegeneration. 10: 26. PMID 26159606 DOI: 10.1186/S13024-015-0022-Y |
0.31 |
|
2015 |
Wolozin B, Apicco D. RNA binding proteins and the genesis of neurodegenerative diseases. Advances in Experimental Medicine and Biology. 822: 11-5. PMID 25416971 DOI: 10.1007/978-3-319-08927-0_3 |
0.386 |
|
2015 |
Vanderweyde T, Youmans-Kidder K, Apicco DJ, Ash PEA, Cook C, Petrucelli L, Wolozin B. Interaction between microtubule-associated protein tau and RNA binding proteins stimulates tau misfolding and stress granule formation Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.07.417 |
0.374 |
|
2014 |
Ash PE, Vanderweyde TE, Youmans KL, Apicco DJ, Wolozin B. Pathological stress granules in Alzheimer's disease. Brain Research. 1584: 52-8. PMID 25108040 DOI: 10.1016/J.Brainres.2014.05.052 |
0.388 |
|
2014 |
Boon JY, Dusonchet J, Trengrove C, Wolozin B. Interaction of LRRK2 with kinase and GTPase signaling cascades. Frontiers in Molecular Neuroscience. 7: 64. PMID 25071441 DOI: 10.3389/Fnmol.2014.00064 |
0.357 |
|
2014 |
Dusonchet J, Li H, Guillily M, Liu M, Stafa K, Derada Troletti C, Boon JY, Saha S, Glauser L, Mamais A, Citro A, Youmans KL, Liu L, Schneider BL, Aebischer P, ... ... Wolozin B, et al. A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity. Human Molecular Genetics. 23: 4887-905. PMID 24794857 DOI: 10.1093/Hmg/Ddu202 |
0.345 |
|
2014 |
Liu-Yesucevitz L, Lin AY, Ebata A, Boon JY, Reid W, Xu YF, Kobrin K, Murphy GJ, Petrucelli L, Wolozin B. ALS-linked mutations enlarge TDP-43-enriched neuronal RNA granules in the dendritic arbor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 4167-74. PMID 24647938 DOI: 10.1523/Jneurosci.2350-13.2014 |
0.339 |
|
2014 |
Saha S, Liu-Yesucevitz L, Wolozin B. Regulation of autophagy by LRRK2 in Caenorhabditis elegans. Neuro-Degenerative Diseases. 13: 110-3. PMID 24192129 DOI: 10.1159/000355654 |
0.337 |
|
2014 |
Boyd JD, Lee-Armandt JP, Feiler MS, Zaarur N, Liu M, Kraemer B, Concannon JB, Ebata A, Wolozin B, Glicksman MA. A high-content screen identifies novel compounds that inhibit stress-induced TDP-43 cellular aggregation and associated cytotoxicity. Journal of Biomolecular Screening. 19: 44-56. PMID 24019256 DOI: 10.1177/1087057113501553 |
0.362 |
|
2013 |
Leung A, Nah SK, Reid W, Ebata A, Koch CM, Monti S, Genereux JC, Wiseman RL, Wolozin B, Connors LH, Berk JL, Seldin DC, Mostoslavsky G, Kotton DN, Murphy GJ. Induced pluripotent stem cell modeling of multisystemic, hereditary transthyretin amyloidosis. Stem Cell Reports. 1: 451-63. PMID 24286032 DOI: 10.1016/J.Stemcr.2013.10.003 |
0.343 |
|
2013 |
Vanderweyde T, Youmans K, Liu-Yesucevitz L, Wolozin B. Role of stress granules and RNA-binding proteins in neurodegeneration: a mini-review. Gerontology. 59: 524-33. PMID 24008580 DOI: 10.1159/000354170 |
0.442 |
|
2013 |
Rodriguez-Ortiz CJ, Hoshino H, Cheng D, Liu-Yescevitz L, Blurton-Jones M, Wolozin B, LaFerla FM, Kitazawa M. Neuronal-specific overexpression of a mutant valosin-containing protein associated with IBMPFD promotes aberrant ubiquitin and TDP-43 accumulation and cognitive dysfunction in transgenic mice. The American Journal of Pathology. 183: 504-15. PMID 23747512 DOI: 10.1016/J.Ajpath.2013.04.014 |
0.376 |
|
2013 |
Wolozin B, Vanderwyede T, Liu-Yesucevitz L, Dedeoglu A, Petrucelli L, Duff K. P4-034: Viewing neurodegeneration beyond the tangle: The role of RNA binding proteins in Alzheimer's disease Alzheimer's & Dementia. 9: P715-P716. DOI: 10.1016/J.Jalz.2013.05.1422 |
0.389 |
|
2012 |
Wolozin B. Regulated protein aggregation: stress granules and neurodegeneration. Molecular Neurodegeneration. 7: 56. PMID 23164372 DOI: 10.1186/1750-1326-7-56 |
0.397 |
|
2012 |
Vanderweyde T, Yu H, Varnum M, Liu-Yesucevitz L, Citro A, Ikezu T, Duff K, Wolozin B. Contrasting pathology of the stress granule proteins TIA-1 and G3BP in tauopathies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8270-83. PMID 22699908 DOI: 10.1523/Jneurosci.1592-12.2012 |
0.469 |
|
2012 |
Youmans KL, Wolozin B. TDP-43: a new player on the AD field? Experimental Neurology. 237: 90-5. PMID 22691390 DOI: 10.1016/J.Expneurol.2012.05.018 |
0.378 |
|
2012 |
Di Domenico F, Sultana R, Ferree A, Smith K, Barone E, Perluigi M, Coccia R, Pierce W, Cai J, Mancuso C, Squillace R, Wiengele M, Dalle-Donne I, Wolozin B, Butterfield DA. Redox proteomics analyses of the influence of co-expression of wild-type or mutated LRRK2 and Tau on C. elegans protein expression and oxidative modification: relevance to Parkinson disease. Antioxidants & Redox Signaling. 17: 1490-506. PMID 22315971 DOI: 10.1089/Ars.2011.4312 |
0.377 |
|
2012 |
Wolozin B. Statins and therapy of Alzheimer's disease: questions of efficacy versus trial design. Alzheimer's Research & Therapy. 4: 3. PMID 22264400 DOI: 10.1186/Alzrt101 |
0.371 |
|
2012 |
Ferree A, Guillily M, Li H, Smith K, Takashima A, Squillace R, Weigele M, Collins JJ, Wolozin B. Regulation of physiologic actions of LRRK2: focus on autophagy. Neuro-Degenerative Diseases. 10: 238-41. PMID 22204929 DOI: 10.1159/000332599 |
0.379 |
|
2011 |
Liu-Yesucevitz L, Bassell GJ, Gitler AD, Hart AC, Klann E, Richter JD, Warren ST, Wolozin B. Local RNA translation at the synapse and in disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 16086-93. PMID 22072660 DOI: 10.1523/Jneurosci.4105-11.2011 |
0.364 |
|
2011 |
Chan D, Citro A, Cordy JM, Shen GC, Wolozin B. Rac1 protein rescues neurite retraction caused by G2019S leucine-rich repeat kinase 2 (LRRK2). The Journal of Biological Chemistry. 286: 16140-9. PMID 21454543 DOI: 10.1074/Jbc.M111.234005 |
0.345 |
|
2011 |
Wolozin B, Gabel C, Ferree A, Guillily M, Ebata A. Watching worms whither: modeling neurodegeneration in C. elegans. Progress in Molecular Biology and Translational Science. 100: 499-514. PMID 21377635 DOI: 10.1016/B978-0-12-384878-9.00015-7 |
0.395 |
|
2011 |
Wolozin B, Vanderwyede T, Liu-Yesucevitz L, McKee A, Duff K. O3-05-02: Stress granules and Alzheimer's disease: Colocalization with tau pathology Alzheimer's & Dementia. 7: S507-S507. DOI: 10.1016/J.Jalz.2011.05.1417 |
0.374 |
|
2010 |
Liu-Yesucevitz L, Bilgutay A, Zhang YJ, Vanderweyde T, Vanderwyde T, Citro A, Mehta T, Zaarur N, McKee A, Bowser R, Sherman M, Petrucelli L, Wolozin B. Tar DNA binding protein-43 (TDP-43) associates with stress granules: analysis of cultured cells and pathological brain tissue. Plos One. 5: e13250. PMID 20948999 DOI: 10.1371/Journal.Pone.0013250 |
0.396 |
|
2010 |
Hsu CH, Chan D, Wolozin B. LRRK2 and the stress response: interaction with MKKs and JNK-interacting proteins. Neuro-Degenerative Diseases. 7: 68-75. PMID 20173330 DOI: 10.1159/000285509 |
0.339 |
|
2010 |
Kumar A, Greggio E, Beilina A, Kaganovich A, Chan D, Taymans JM, Wolozin B, Cookson MR. The Parkinson's disease associated LRRK2 exhibits weaker in vitro phosphorylation of 4E-BP compared to autophosphorylation. Plos One. 5: e8730. PMID 20090955 DOI: 10.1371/Journal.Pone.0008730 |
0.327 |
|
2010 |
Carballo-Carbajal I, Weber-Endress S, Rovelli G, Chan D, Wolozin B, Klein CL, Patenge N, Gasser T, Kahle PJ. Leucine-rich repeat kinase 2 induces alpha-synuclein expression via the extracellular signal-regulated kinase pathway. Cellular Signalling. 22: 821-7. PMID 20074637 DOI: 10.1016/J.Cellsig.2010.01.006 |
0.315 |
|
2010 |
Hsu CH, Chan D, Greggio E, Saha S, Guillily MD, Ferree A, Raghavan K, Shen GC, Segal L, Ryu H, Cookson MR, Wolozin B. MKK6 binds and regulates expression of Parkinson's disease-related protein LRRK2. Journal of Neurochemistry. 112: 1593-604. PMID 20067578 DOI: 10.1111/J.1471-4159.2010.06568.X |
0.395 |
|
2010 |
Wolozin B. C. elegans models of Alzheimer's disease and Parkinson's disease: Systems biology identifies LRRK2 shared interaction networks Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.517 |
0.341 |
|
2010 |
Wolozin B, Guillily M, Ferree A, Li H, Pyenson N, Smith K, Saha S, Ebata A, Gabel CV, Collins JJ. C. elegans models of Alzheimer's disease and Parkinson's disease: Systems biology identifies an interaction between tau and LRRK2 Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.232 |
0.375 |
|
2009 |
Saha S, Guillily MD, Ferree A, Lanceta J, Chan D, Ghosh J, Hsu CH, Segal L, Raghavan K, Matsumoto K, Hisamoto N, Kuwahara T, Iwatsubo T, Moore L, Goldstein L, ... ... Wolozin B, et al. LRRK2 modulates vulnerability to mitochondrial dysfunction in Caenorhabditis elegans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 9210-8. PMID 19625511 DOI: 10.1523/Jneurosci.2281-09.2009 |
0.315 |
|
2009 |
Tezapsidis N, Johnston JM, Smith MA, Ashford JW, Casadesus G, Robakis NK, Wolozin B, Perry G, Zhu X, Greco SJ, Sarkar S. Leptin: a novel therapeutic strategy for Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 16: 731-40. PMID 19387109 DOI: 10.3233/Jad-2009-1021 |
0.389 |
|
2008 |
Zerbinatti CV, Cordy JM, Chen CD, Guillily M, Suon S, Ray WJ, Seabrook GR, Abraham CR, Wolozin B. Oxysterol-binding protein-1 (OSBP1) modulates processing and trafficking of the amyloid precursor protein. Molecular Neurodegeneration. 3: 5. PMID 18348724 DOI: 10.1186/1750-1326-3-5 |
0.394 |
|
2008 |
Wolozin B, Saha S, Guillily M, Ferree A, Riley M. Investigating convergent actions of genes linked to familial Parkinson's disease. Neuro-Degenerative Diseases. 5: 182-5. PMID 18322385 DOI: 10.1159/000113697 |
0.307 |
|
2008 |
Wolozin B, Lee A, Lee A, Whitmer R, Kazis L. O1-05-05: Use of angiotensin receptor blockers is associated with a lower incidence and progression of Alzheimer's disease Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.251 |
0.321 |
|
2007 |
Wolozin B, Wang SW, Li NC, Lee A, Lee TA, Kazis LE. Simvastatin is associated with a reduced incidence of dementia and Parkinson's disease. Bmc Medicine. 5: 20. PMID 17640385 DOI: 10.1186/1741-7015-5-20 |
0.351 |
|
2006 |
Wolozin B, Bednar MM. Interventions for heart disease and their effects on Alzheimer's disease. Neurological Research. 28: 630-6. PMID 16945215 DOI: 10.1179/016164106X130515 |
0.369 |
|
2006 |
Wolozin B, Manger J, Bryant R, Cordy J, Green RC, McKee A. Re-assessing the relationship between cholesterol, statins and Alzheimer's disease. Acta Neurologica Scandinavica. Supplementum. 185: 63-70. PMID 16866913 DOI: 10.1111/J.1600-0404.2006.00687.X |
0.367 |
|
2006 |
Takashima A, Shimojo M, Wolozin B. The players on the gamma-secretase team. Nature Medicine. 12: 766-7; discussion 76. PMID 16829940 DOI: 10.1038/Nm0706-766 |
0.31 |
|
2006 |
Cordy JM, Zerbinatti CV, Chen C, Guillily M, Ray WJ, Seabrook GR, Abraham CR, Wolozin B. P4-077: Modulation of amyloid precursor protein-processing by oxysterol-binding protein Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1815 |
0.333 |
|
2005 |
Lee TA, Wolozin B, Weiss KB, Bednar MM. Assessment of the emergence of Alzheimer's disease following coronary artery bypass graft surgery or percutaneous transluminal coronary angioplasty. Journal of Alzheimer's Disease : Jad. 7: 319-24. PMID 16131734 DOI: 10.3233/Jad-2005-7408 |
0.307 |
|
2005 |
Poon HF, Frasier M, Shreve N, Calabrese V, Wolozin B, Butterfield DA. Mitochondrial associated metabolic proteins are selectively oxidized in A30P alpha-synuclein transgenic mice--a model of familial Parkinson's disease. Neurobiology of Disease. 18: 492-8. PMID 15755676 DOI: 10.1016/J.Nbd.2004.12.009 |
0.333 |
|
2005 |
Frasier M, Walzer M, McCarthy L, Magnuson D, Lee JM, Haas C, Kahle P, Wolozin B. Tau phosphorylation increases in symptomatic mice overexpressing A30P alpha-synuclein. Experimental Neurology. 192: 274-87. PMID 15755545 DOI: 10.1016/J.Expneurol.2004.07.016 |
0.367 |
|
2005 |
Snyder H, Mensah K, Hsu C, Hashimoto M, Surgucheva IG, Festoff B, Surguchov A, Masliah E, Matouschek A, Wolozin B. beta-Synuclein reduces proteasomal inhibition by alpha-synuclein but not gamma-synuclein. The Journal of Biological Chemistry. 280: 7562-9. PMID 15591046 DOI: 10.1074/Jbc.M412887200 |
0.309 |
|
2004 |
Snyder H, Wolozin B. Pathological proteins in Parkinson's disease: focus on the proteasome. Journal of Molecular Neuroscience : Mn. 24: 425-42. PMID 15655264 DOI: 10.1385/Jmn:24:3:425 |
0.331 |
|
2004 |
Wolozin B. Cholesterol, statins and dementia. Current Opinion in Lipidology. 15: 667-72. PMID 15529026 DOI: 10.1097/00041433-200412000-00007 |
0.375 |
|
2004 |
Wolozin B, Brown J, Theisler C, Silberman S. The cellular biochemistry of cholesterol and statins: insights into the pathophysiology and therapy of Alzheimer's disease. Cns Drug Reviews. 10: 127-46. PMID 15179443 DOI: 10.1111/J.1527-3458.2004.Tb00009.X |
0.368 |
|
2004 |
Brown J, Theisler C, Silberman S, Magnuson D, Gottardi-Littell N, Lee JM, Yager D, Crowley J, Sambamurti K, Rahman MM, Reiss AB, Eckman CB, Wolozin B. Differential expression of cholesterol hydroxylases in Alzheimer's disease. The Journal of Biological Chemistry. 279: 34674-81. PMID 15148325 DOI: 10.1074/Jbc.M402324200 |
0.4 |
|
2004 |
Petrucelli L, Dickson D, Kehoe K, Taylor J, Snyder H, Grover A, De Lucia M, McGowan E, Lewis J, Prihar G, Kim J, Dillmann WH, Browne SE, Hall A, Voellmy R, ... ... Wolozin B, et al. CHIP and Hsp70 regulate tau ubiquitination, degradation and aggregation. Human Molecular Genetics. 13: 703-14. PMID 14962978 DOI: 10.1093/Hmg/Ddh083 |
0.406 |
|
2004 |
Wolozin B. Cholesterol and the biology of Alzheimer's disease. Neuron. 41: 7-10. PMID 14715130 DOI: 10.1016/S0896-6273(03)00840-7 |
0.378 |
|
2004 |
Wolozin B, Brown J, Silberman S, Theisler C, Yager D, Crawley J, Magnuson D, Reiss A, Lee JM, Eckman C. P4-191 Differential expression of cholesterol 24-hydroxylase and cholesterol 27-hydroxylase in Alzheimer's disease Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)81749-4 |
0.32 |
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2004 |
Wolozin B, Lee TA, Weiss K, Bednar MM. S1-03-06 Reduced incidence of Alzheimer's disease among subjects exposed to general anesthesia in non-cardiac operations: a retrospective analysis Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80021-6 |
0.31 |
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2003 |
Choi P, Snyder H, Petrucelli L, Theisler C, Chong M, Zhang Y, Lim K, Chung KK, Kehoe K, D'Adamio L, Lee JM, Cochran E, Bowser R, Dawson TM, Wolozin B. SEPT5_v2 is a parkin-binding protein. Brain Research. Molecular Brain Research. 117: 179-89. PMID 14559152 DOI: 10.1016/S0169-328X(03)00318-8 |
0.327 |
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2003 |
Perry G, Castellani RJ, Smith MA, Harris PL, Kubat Z, Ghanbari K, Jones PK, Cordone G, Tabaton M, Wolozin B, Ghanbari H. Oxidative damage in the olfactory system in Alzheimer's disease. Acta Neuropathologica. 106: 552-6. PMID 12955399 DOI: 10.1007/S00401-003-0761-7 |
0.359 |
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2003 |
Pappolla MA, Bryant-Thomas TK, Herbert D, Pacheco J, Fabra Garcia M, Manjon M, Girones X, Henry TL, Matsubara E, Zambon D, Wolozin B, Sano M, Cruz-Sanchez FF, Thal LJ, Petanceska SS, et al. Mild hypercholesterolemia is an early risk factor for the development of Alzheimer amyloid pathology. Neurology. 61: 199-205. PMID 12874399 DOI: 10.1212/01.Wnl.0000070182.02537.84 |
0.356 |
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2003 |
Snyder H, Mensah K, Theisler C, Lee J, Matouschek A, Wolozin B. Aggregated and monomeric alpha-synuclein bind to the S6' proteasomal protein and inhibit proteasomal function. The Journal of Biological Chemistry. 278: 11753-9. PMID 12551928 DOI: 10.1074/Jbc.M208641200 |
0.317 |
|
2003 |
Wolozin B. Cyp46 (24S-cholesterol hydroxylase): a genetic risk factor for Alzheimer disease. Archives of Neurology. 60: 16-8. PMID 12533083 DOI: 10.1001/Archneur.60.1.16 |
0.309 |
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2002 |
Egashira N, Iwasaki K, Ishibashi M, Hatip-Al-Khatib I, Wolozin B, Mishima K, Irie K, Fujiwara M. Hypoxia enhances beta-amyloid-induced apoptosis in rat cultured hippocampal neurons. Japanese Journal of Pharmacology. 90: 321-7. PMID 12501008 DOI: 10.1254/Jjp.90.321 |
0.329 |
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2002 |
Petrucelli L, O'Farrell C, Lockhart PJ, Baptista M, Kehoe K, Vink L, Choi P, Wolozin B, Farrer M, Hardy J, Cookson MR. Parkin protects against the toxicity associated with mutant alpha-synuclein: proteasome dysfunction selectively affects catecholaminergic neurons. Neuron. 36: 1007-19. PMID 12495618 DOI: 10.1016/S0896-6273(02)01125-X |
0.335 |
|
2002 |
Wolozin B. Cholesterol and Alzheimer's disease. Biochemical Society Transactions. 30: 525-9. PMID 12196129 DOI: 10.1042/Bst0300525 |
0.347 |
|
2002 |
Ahn BH, Rhim H, Kim SY, Sung YM, Lee MY, Choi JY, Wolozin B, Chang JS, Lee YH, Kwon TK, Chung KC, Yoon SH, Hahn SJ, Kim MS, Jo YH, et al. alpha-Synuclein interacts with phospholipase D isozymes and inhibits pervanadate-induced phospholipase D activation in human embryonic kidney-293 cells. The Journal of Biological Chemistry. 277: 12334-42. PMID 11821392 DOI: 10.1074/Jbc.M110414200 |
0.338 |
|
2001 |
Wolozin B. Peering into proteolysis with presenilins. Journal of Alzheimer's Disease : Jad. 3: 191-193. PMID 12214060 DOI: 10.3233/Jad-2001-3204 |
0.387 |
|
2001 |
Wolozin B. A fluid connection: cholesterol and Abeta. Proceedings of the National Academy of Sciences of the United States of America. 98: 5371-3. PMID 11344276 DOI: 10.1073/Pnas.101123198 |
0.369 |
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2000 |
Wolozin B, Kellman W, Ruosseau P, Celesia GG, Siegel G. Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors. Archives of Neurology. 57: 1439-43. PMID 11030795 DOI: 10.1001/Archneur.57.10.1439 |
0.332 |
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2000 |
Choi P, Ostrerova-Golts N, Sparkman D, Cochran E, Lee JM, Wolozin B. Parkin is metabolized by the ubiquitin/proteosome system. Neuroreport. 11: 2635-8. PMID 10976934 DOI: 10.1097/00001756-200008210-00006 |
0.307 |
|
2000 |
Wolozin B, Behl C. Mechanisms of neurodegenerative disorders: Part 2: control of cell death. Archives of Neurology. 57: 801-4. PMID 10867776 DOI: 10.1001/Archneur.57.6.801 |
0.358 |
|
2000 |
Wolozin B, Behl C. Mechanisms of neurodegenerative disorders: Part 1: protein aggregates. Archives of Neurology. 57: 793-6. PMID 10867775 DOI: 10.1001/Archneur.57.6.793 |
0.345 |
|
2000 |
Palacino JJ, Berechid BE, Alexander P, Eckman C, Younkin S, Nye JS, Wolozin B. Regulation of amyloid precursor protein processing by presenilin 1 (PS1) and PS2 in PS1 knockout cells. The Journal of Biological Chemistry. 275: 215-22. PMID 10617607 DOI: 10.1074/Jbc.275.1.215 |
0.345 |
|
2000 |
Ostrerova-Golts N, Petrucelli L, Hardy J, Lee JM, Farer M, Wolozin B. The A53T α-Synuclein Mutation Increases Iron-Dependent Aggregation and Toxicity The Journal of Neuroscience. 20: 6048-6054. DOI: 10.1523/Jneurosci.20-16-06048.2000 |
0.31 |
|
2000 |
Wolozin B. The physiology and pathophysiology of α-synuclein: A protein chaperone that aggregates Neurobiology of Aging. 21: 283. DOI: 10.1016/S0197-4580(00)83224-8 |
0.315 |
|
1999 |
Sunderland T, Wolozin B, Galasko D, Levy J, Dukoff R, Bahro M, Lasser R, Motter R, Lehtimäki T, Seubert P. Longitudinal stability of CSF tau levels in Alzheimer patients. Biological Psychiatry. 46: 750-5. PMID 10494442 DOI: 10.1016/S0006-3223(99)00143-2 |
0.343 |
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1999 |
Ostrerova N, Petrucelli L, Farrer M, Mehta N, Choi P, Hardy J, Wolozin B. α-Synuclein Shares Physical and Functional Homology with 14-3-3 Proteins The Journal of Neuroscience. 19: 5782-5791. DOI: 10.1523/Jneurosci.19-14-05782.1999 |
0.35 |
|
1998 |
Wolozin B, Maheshwari S, Jones C, Dukoff R, Wallace W, Racchi M, Nagula S, Shulman NR, Sunderland T, Bush A. Beta-amyloid augments platelet aggregation: reduced activity of familial angiopathy-associated mutants. Molecular Psychiatry. 3: 500-7. PMID 9857975 DOI: 10.1038/Sj.Mp.4000451 |
0.329 |
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1998 |
Murayama M, Tanaka S, Palacino J, Murayama O, Honda T, Sun X, Yasutake K, Nihonmatsu N, Wolozin B, Takashima A. Direct association of presenilin-1 with beta-catenin. Febs Letters. 433: 73-7. PMID 9738936 DOI: 10.1016/S0014-5793(98)00886-2 |
0.316 |
|
1998 |
Takashima A, Murayama M, Murayama O, Kohno T, Honda T, Yasutake K, Nihonmatsu N, Mercken M, Yamaguchi H, Sugihara S, Wolozin B. Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau. Proceedings of the National Academy of Sciences of the United States of America. 95: 9637-41. PMID 9689133 DOI: 10.1073/Pnas.95.16.9637 |
0.361 |
|
1998 |
Wolozin B, Alexander P, Palacino J. Regulation of apoptosis by presenilin 1. Neurobiology of Aging. 19: S23-7. PMID 9562463 DOI: 10.1016/S0197-4580(98)00041-4 |
0.312 |
|
1997 |
Luo Y, Hawver DB, Iwasaki K, Sunderland T, Roth GS, Wolozin B. Physiological levels of beta-amyloid peptide stimulate protein kinase C in PC12 cells. Brain Research. 769: 287-95. PMID 9374197 DOI: 10.1016/S0006-8993(97)00718-X |
0.36 |
|
1996 |
Vito P, Wolozin B, Ganjei JK, Iwasaki K, Lacanà E, D'Adamio L. Requirement of the familial Alzheimer's disease gene PS2 for apoptosis. Opposing effect of ALG-3. The Journal of Biological Chemistry. 271: 31025-8. PMID 8940094 DOI: 10.1074/Jbc.271.49.31025 |
0.304 |
|
1996 |
Wolozin B, Iwasaki K, Vito P, Ganjei JK, Lacanà E, Sunderland T, Zhao B, Kusiak JW, Wasco W, D'Adamio L. Participation of presenilin 2 in apoptosis: enhanced basal activity conferred by an Alzheimer mutation. Science (New York, N.Y.). 274: 1710-3. PMID 8939861 DOI: 10.1126/Science.274.5293.1710 |
0.403 |
|
1996 |
Luo Y, Sunderland T, Roth GS, Wolozin B. Physiological levels of beta-amyloid peptide promote PC12 cell proliferation. Neuroscience Letters. 217: 125-8. PMID 8916088 DOI: 10.1016/0304-3940(96)13087-1 |
0.347 |
|
1994 |
Johnson GS, Basaric-Keys J, Ghanbari HA, Lebovics RS, Lesch KP, Merril CR, Sunderland T, Wolozin B. Protein alterations in olfactory neuroblasts from Alzheimer donors. Neurobiology of Aging. 15: 675-80. PMID 7891821 DOI: 10.1016/0197-4580(94)90048-5 |
0.38 |
|
1993 |
Wolozin B, Lesch P, Lebovics R, Sunderland T. Olfactory neuroblasts from Alzheimer donors: Studies on APP processing and cell regulation Biological Psychiatry. 34: 824-838. PMID 8110910 DOI: 10.1016/0006-3223(93)90051-E |
0.387 |
|
1992 |
Wolozin B, Bacic M, Merrill MJ, Lesch KP, Chen C, Lebovics RS, Sunderland T. Differential expression of carboxyl terminal derivatives of amyloid precursor protein among cell lines. Journal of Neuroscience Research. 33: 163-9. PMID 1453480 DOI: 10.1002/Jnr.490330121 |
0.38 |
|
1988 |
Wolozin B, Scicutella A, Davies P. Reexpression of a developmentally regulated antigen in Down syndrome and Alzheimer disease Proceedings of the National Academy of Sciences of the United States of America. 85: 6202-6206. PMID 2970636 DOI: 10.1073/Pnas.85.16.6202 |
0.341 |
|
1987 |
Wolozin B, Davies P. Alzheimer-related neuronal protein A68: Specificity and distribution Annals of Neurology. 22: 521-526. PMID 3435070 DOI: 10.1002/Ana.410220412 |
0.364 |
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