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Alexander Kleschevnikov - Publications

Affiliations: 
Neurosciences University of California, San Diego, La Jolla, CA 
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21/50 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Egawa J, Zemljic-Harpf A, Mandyam CD, Niesman IR, Lysenko LV, Kleschevnikov AM, Roth DM, Patel HH, Patel PM, Head BP. Neuron-Targeted Caveolin-1 Promotes Ultrastructural and Functional Hippocampal Synaptic Plasticity. Cerebral Cortex (New York, N.Y. : 1991). 1-12. PMID 28981594 DOI: 10.1093/Cercor/Bhx196  0.318
2017 Kleschevnikov AM, Yu J, Kim J, Lysenko LV, Zhen Z, Eugene Yu Y, Mobley WC. Evidence that increased Kcnj6 gene dose is necessary for deficits in behavior and dentate gyrus synaptic plasticity in the Ts65Dn mouse model of Down syndrome. Neurobiology of Disease. PMID 28342823 DOI: 10.1016/J.Nbd.2017.03.009  0.348
2016 Mojabi FS, Fahimi A, Moghadam S, Moghadam S, McNerneny MW, Ponnusamy R, Kleschevnikov A, Mobley WC, Salehi A. GABAergic Hyperinnervation of Dentate Granule Cells in the Ts65Dn Mouse Model of Down Syndrome Exploring the Role of App. Hippocampus. PMID 27701794 DOI: 10.1002/Hipo.22664  0.346
2015 Belichenko PV, Kleschevnikov AM, Becker A, Wagner GE, Lysenko LV, Yu YE, Mobley WC. Down Syndrome Cognitive Phenotypes Modeled in Mice Trisomic for All HSA 21 Homologues. Plos One. 10: e0134861. PMID 26230397 DOI: 10.1371/Journal.Pone.0134861  0.34
2015 Schilling J, Mandyam C, Kellerhals S, Egawa J, Risbrough V, Niesman I, Posadas E, Kleschevnikov A, Roth D, Patel H, Patel P, Head B. Neuron-Targeted Caveolin-1 Improves Cognition and Enhances Hippocampal Plasticity The Faseb Journal. 29. DOI: 10.1096/Fasebj.29.1_Supplement.837.1  0.339
2014 Lysenko LV, Kim J, Henry C, Tyrtyshnaia A, Kohnz RA, Madamba F, Simon GM, Kleschevnikova NE, Nomura DK, Ezekowitz RA, Kleschevnikov AM. Monoacylglycerol lipase inhibitor JZL184 improves behavior and neural properties in Ts65Dn mice, a model of down syndrome. Plos One. 9: e114521. PMID 25474204 DOI: 10.1371/Journal.Pone.0114521  0.345
2014 Zhang L, Meng K, Jiang X, Liu C, Pao A, Belichenko PV, Kleschevnikov AM, Josselyn S, Liang P, Ye P, Mobley WC, Yu YE. Human chromosome 21 orthologous region on mouse chromosome 17 is a major determinant of Down syndrome-related developmental cognitive deficits. Human Molecular Genetics. 23: 578-89. PMID 24041763 DOI: 10.1093/Hmg/Ddt446  0.315
2012 Kleschevnikov AM, Belichenko PV, Faizi M, Jacobs LF, Htun K, Shamloo M, Mobley WC. Deficits in cognition and synaptic plasticity in a mouse model of Down syndrome ameliorated by GABAB receptor antagonists. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 9217-27. PMID 22764230 DOI: 10.1523/Jneurosci.1673-12.2012  0.343
2012 Kleschevnikov AM, Belichenko PV, Salehi A, Wu C. Discoveries in Down syndrome: moving basic science to clinical care. Progress in Brain Research. 197: 199-221. PMID 22541294 DOI: 10.1016/B978-0-444-54299-1.00010-8  0.302
2012 Kleschevnikov AM, Belichenko PV, Gall J, George L, Nosheny R, Maloney MT, Salehi A, Mobley WC. Increased efficiency of the GABAA and GABAB receptor-mediated neurotransmission in the Ts65Dn mouse model of Down syndrome. Neurobiology of Disease. 45: 683-91. PMID 22062771 DOI: 10.1016/J.Nbd.2011.10.009  0.356
2011 Faizi M, Bader PL, Tun C, Encarnacion A, Kleschevnikov A, Belichenko P, Saw N, Priestley M, Tsien RW, Mobley WC, Shamloo M. Comprehensive behavioral phenotyping of Ts65Dn mouse model of Down syndrome: activation of β1-adrenergic receptor by xamoterol as a potential cognitive enhancer. Neurobiology of Disease. 43: 397-413. PMID 21527343 DOI: 10.1016/J.Nbd.2011.04.011  0.359
2011 Popov VI, Kleschevnikov AM, Klimenko OA, Stewart MG, Belichenko PV. Three-dimensional synaptic ultrastructure in the dentate gyrus and hippocampal area CA3 in the Ts65Dn mouse model of Down syndrome. The Journal of Comparative Neurology. 519: 1338-54. PMID 21452200 DOI: 10.1002/cne.22573  0.312
2010 Yu T, Liu C, Belichenko P, Clapcote SJ, Li S, Pao A, Kleschevnikov A, Bechard AR, Asrar S, Chen R, Fan N, Zhou Z, Jia Z, Chen C, Roder JC, et al. Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice. Brain Research. 1366: 162-71. PMID 20932954 DOI: 10.1016/J.Brainres.2010.09.107  0.37
2009 Salehi A, Faizi M, Colas D, Valletta J, Laguna J, Takimoto-Kimura R, Kleschevnikov A, Wagner SL, Aisen P, Shamloo M, Mobley WC. Restoration of norepinephrine-modulated contextual memory in a mouse model of Down syndrome. Science Translational Medicine. 1: 7ra17. PMID 20368182 DOI: 10.1126/Scitranslmed.3000258  0.354
2009 Belichenko NP, Belichenko PV, Kleschevnikov AM, Salehi A, Reeves RH, Mobley WC. The "Down syndrome critical region" is sufficient in the mouse model to confer behavioral, neurophysiological, and synaptic phenotypes characteristic of Down syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 5938-48. PMID 19420260 DOI: 10.1523/Jneurosci.1547-09.2009  0.358
2009 Belichenko PV, Kleschevnikov AM, Masliah E, Wu C, Takimoto-Kimura R, Salehi A, Mobley WC. Excitatory-inhibitory relationship in the fascia dentata in the Ts65Dn mouse model of Down syndrome. The Journal of Comparative Neurology. 512: 453-66. PMID 19034952 DOI: 10.1002/Cne.21895  0.329
2007 Belichenko PV, Kleschevnikov AM, Salehi A, Epstein CJ, Mobley WC. Synaptic and cognitive abnormalities in mouse models of Down syndrome: exploring genotype-phenotype relationships. The Journal of Comparative Neurology. 504: 329-45. PMID 17663443 DOI: 10.1002/Cne.21433  0.357
2004 Belichenko PV, Masliah E, Kleschevnikov AM, Villar AJ, Epstein CJ, Salehi A, Mobley WC. Synaptic structural abnormalities in the Ts65Dn mouse model of Down Syndrome. The Journal of Comparative Neurology. 480: 281-98. PMID 15515178 DOI: 10.1002/Cne.20337  0.336
2004 Kleschevnikov AM, Belichenko PV, Villar AJ, Epstein CJ, Malenka RC, Mobley WC. Hippocampal long-term potentiation suppressed by increased inhibition in the Ts65Dn mouse, a genetic model of Down syndrome. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8153-60. PMID 15371516 DOI: 10.1523/Jneurosci.1766-04.2004  0.4
2000 Bayazitov I, Kleschevnikov A. Afferent high strength tetanizations favour potentiation of the NMDA vs. AMPA receptor-mediated component of field EPSP in CA1 hippocampal slices of rats Brain Research. 866: 188-196. PMID 10825494 DOI: 10.1016/S0006-8993(00)02279-4  0.318
1995 Voronin L, Byzov A, Kleschevnikov A, Kozhemyakin M, Kuhnt U, Volgushev M. Neurophysiological analysis of long-term potentiation in mammalian brain. Behavioural Brain Research. 66: 45-52. PMID 7755898 DOI: 10.1016/0166-4328(94)00123-W  0.347
Low-probability matches (unlikely to be authored by this person)
1998 Kleschevnikov AM. Long-term potentiation of the nmda-dependent component of epsp in the hippocampus Uspekhi Fiziologicheskikh Nauk. 29: 19-23. PMID 9883495  0.287
2011 Liu C, Belichenko PV, Zhang L, Fu D, Kleschevnikov AM, Baldini A, Antonarakis SE, Mobley WC, Yu YE. Mouse models for Down syndrome-associated developmental cognitive disabilities. Developmental Neuroscience. 33: 404-13. PMID 21865664 DOI: 10.1159/000329422  0.283
2001 Kleschevnikov AM, Routtenberg A. PKC activation rescues LTP from NMDA receptor blockade. Hippocampus. 11: 168-75. PMID 11345123 DOI: 10.1002/hipo.1034  0.281
2002 Kleschevnikov AM, Kuhnt U, Voronin LL. Quantal analysis of the late phase of long-term potentiation (LTP) in the guinea pig hippocampal slices: Sharp microelectrode recordings Neuroscience Research Communications. 30: 7-25. DOI: 10.1002/Nrc.10013  0.279
1998 Kleschevnikov AM. Synaptic plasticity in hippocampus induced by theta-like pattern of afferent stimulation Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I.P. Pavlova. 48: 14-18.  0.271
2022 Kleschevnikov AM. Enhanced GIRK2 channel signaling in Down syndrome: A feasible role in the development of abnormal nascent neural circuits. Frontiers in Genetics. 13: 1006068. PMID 36171878 DOI: 10.3389/fgene.2022.1006068  0.265
1995 Sokolov MV, Kleschevnikov AM. Atropine suppresses associative LTP in the CA1 region of rat hippocampal slices Brain Research. 672: 281-284. PMID 7749748 DOI: 10.1016/0006-8993(94)01376-S  0.264
2022 Kleschevnikov A. GIRK2 Channels in Down syndrome and Alzheimer's disease. Current Alzheimer Research. PMID 36567290 DOI: 10.2174/1567205020666221223122110  0.26
1993 Kleschevnikov AM, Marchbanks RM. Behavioral parameters of the spatial memory correlate with the potentiation of the population spike, but not with the population excitatory postsynaptic potential, of the CA1 region in rat hippocampal slices Neuroscience Letters. 152: 125-128. PMID 7685862 DOI: 10.1016/0304-3940(93)90499-B  0.258
2018 Savchenko A, Cherkas V, Liu C, Braun GB, Kleschevnikov A, Miller YI, Molokanova E. Graphene biointerfaces for optical stimulation of cells. Science Advances. 4: eaat0351. PMID 29795786 DOI: 10.1126/Sciadv.Aat0351  0.253
2021 Wang S, Leem JS, Podvin S, Hook V, Kleschevnikov N, Savchenko P, Dhanani M, Zhou K, Kelly IC, Zhang T, Miyanohara A, Nguyen P, Kleschevnikov A, Wagner SL, Trojanowski JQ, et al. Synapsin-caveolin-1 gene therapy preserves neuronal and synaptic morphology and prevents neurodegeneration in a mouse model of AD. Molecular Therapy. Methods & Clinical Development. 21: 434-450. PMID 33981778 DOI: 10.1016/j.omtm.2021.03.021  0.249
2018 Savtchenko A, Cherkas V, Kleschevnikov A, Braun G, Zaretski A, Lipomi DL, Wei K, Molokanova E. Graphene Biointerfaces for Optical Stimulation of Genetically Intact Cells Biophysical Journal. 114: 14a. DOI: 10.1016/J.Bpj.2017.11.122  0.245
1994 Kuhnt U, Kleschevnikov AM, Voronin LL. Long-term enhancement of synaptic transmission in the hippocampus after tetanization of single neurones by short intracellular current pulses Neuroscience Research Communications. 14: 115-123.  0.232
1998 Bazhenov AV, Kleschevnikov AM. Reciprocal suppression of AMPA and NMDA components of EPSP in the CA1 area of rat hippocampal slices in vitro Zhurnal Vysshei Nervnoi Deyatelnosti Imeni I.P. Pavlova. 48: 892-893.  0.23
1997 Kleschevnikov AM, Sokolov MV, Kuhnt U, Dawe GS, Stephenson JD, Voronin LL. Changes in paired-pulse facilitation correlate with induction of long-term potentiation in area CA1 of rat hippocampal slices. Neuroscience. 76: 829-43. PMID 9135055 DOI: 10.1016/S0306-4522(96)00342-9  0.23
2012 Zhang L, Fu D, Belichenko PV, Liu C, Kleschevnikov AM, Pao A, Liang P, Clapcote SJ, Mobley WC, Yu YE. Genetic analysis of Down syndrome facilitated by mouse chromosome engineering. Bioengineered Bugs. 3: 8-12. PMID 22126738 DOI: 10.4161/Bbug.3.1.17696  0.225
2003 Kleschevnikov AM, Routtenberg A. Long-term potentiation recruits a trisynaptic excitatory associative network within the mouse dentate gyrus. The European Journal of Neuroscience. 17: 2690-702. PMID 12823476 DOI: 10.1046/j.1460-9568.2003.02709.x  0.222
1993 Kleschevnikov AM, Marchbanks RM. Heterosynaptic short-term depression of population spike amplitude in the pyramidal layer of the CA1 hippocampal region evoked by a theta-like tetanization Brain Research. 611: 295-299. PMID 8334523 DOI: 10.1016/0006-8993(93)90516-P  0.219
1989 Voronin LL, Davietshin RN, Ivanova EM, Kleschevnikov AM, Kudryashov IE, Fedorov NB. Long-term facilitation after microstimulation in mouse hippocampal slices Doklady Biological Sciences. 305: 261-264.  0.214
2018 Lysenko LV, Kim J, Madamba F, Tyrtyshnaia AA, Ruparelia A, Kleschevnikov AM. Developmental excitatory-to-inhibitory GABA polarity switch is delayed in Ts65Dn mice, a genetic model of Down syndrome. Neurobiology of Disease. 115: 1-8. PMID 29550538 DOI: 10.1016/j.nbd.2018.03.005  0.203
1994 Kleschevnikov AM, Sinden JD, Marchbanks R. Fimbria-fornix lesions impair spatial performance and induce epileptic-like activity but do not affect long-term potentiation in the CA1 region of rat hippocampal slices. Brain Research. 656: 221-8. PMID 7820582 DOI: 10.1016/0006-8993(94)91464-8  0.19
2016 Belichenko PV, Madani R, Rey-Bellet L, Pihlgren M, Becker A, Plassard A, Vuillermot S, Giriens V, Nosheny RL, Kleschevnikov AM, Valletta JS, Bengtsson SK, Linke GR, Maloney MT, Hickman DT, et al. An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome. Plos One. 11: e0152471. PMID 27023444 DOI: 10.1371/Journal.Pone.0152471  0.18
2006 Salehi A, Delcroix JD, Belichenko PV, Zhan K, Wu C, Valletta JS, Takimoto-Kimura R, Kleschevnikov AM, Sambamurti K, Chung PP, Xia W, Villar A, Campbell WA, Kulnane LS, Nixon RA, et al. Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration. Neuron. 51: 29-42. PMID 16815330 DOI: 10.1016/J.Neuron.2006.05.022  0.161
2019 Rafii MS, Kleschevnikov AM, Sawa M, Mobley WC. Down syndrome. Handbook of Clinical Neurology. 167: 321-336. PMID 31753140 DOI: 10.1016/B978-0-12-804766-8.00017-0  0.151
2014 Niesman IR, Schilling JM, Shapiro LA, Kellerhals SE, Bonds JA, Kleschevnikov AM, Cui W, Voong A, Krajewski S, Ali SS, Roth DM, Patel HH, Patel PM, Head BP. Traumatic brain injury enhances neuroinflammation and lesion volume in caveolin deficient mice. Journal of Neuroinflammation. 11: 39. PMID 24593993 DOI: 10.1186/1742-2094-11-39  0.139
2016 Tyrtyshnaia AA, Lysenko LV, Madamba F, Manzhulo IV, Khotimchenko MY, Kleschevnikov AM. Acute neuroinflammation provokes intracellular acidification in mouse hippocampus. Journal of Neuroinflammation. 13: 283. PMID 27809864 DOI: 10.1186/s12974-016-0747-8  0.107
2020 Chen XQ, Salehi A, Pearn ML, Overk C, Nguyen PD, Kleschevnikov AM, Maccecchini M, Mobley WC. Targeting increased levels of APP in Down syndrome: Posiphen-mediated reductions in APP and its products reverse endosomal phenotypes in the Ts65Dn mouse model. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32975365 DOI: 10.1002/alz.12185  0.107
1994 Kozhemyakin MB, Kleschevnikov AM. The M1 antagonist pirenzepine suppresses heterosynaptic STD in the CA1 region. Neuroreport. 5: 1670-2. PMID 7819544  0.097
2014 Zueva OA, Bachev NL, Bulbovich RV, Kleschevnikov AM. Development of a gas turbine plant for associated petroleum gas utilization gathering electrical and thermal energy at marginal fields Neftyanoe Khozyaistvo - Oil Industry. 98-101.  0.019
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