| Year |
Citation |
Score |
| 2024 |
Morgenstern TJ, Darko-Boateng A, Afriyie E, Shanmugam SK, Zhou X, Choudhury P, Desai M, Kass RS, Clarke OB, Colecraft HM. Ion channel inhibition by targeted recruitment of NEDD4-2 with divalent nanobodies. Biorxiv : the Preprint Server For Biology. PMID 38854018 DOI: 10.1101/2024.05.28.596281 |
0.321 |
|
| 2023 |
Zou X, Shanmugam SK, Kanner SA, Sampson KJ, Kass RS, Colecraft HM. Divergent regulation of KCNQ1/E1 by targeted recruitment of protein kinase A to distinct sites on the channel complex. Elife. 12. PMID 37650513 DOI: 10.7554/eLife.83466 |
0.407 |
|
| 2022 |
Zou X, Wu X, Sampson KJ, Colecraft HM, Larsson HP, Kass RS. Pharmacological rescue of specific long QT variants of KCNQ1/KCNE1 channels. Frontiers in Physiology. 13: 902224. PMID 36505078 DOI: 10.3389/fphys.2022.902224 |
0.484 |
|
| 2022 |
Redel-Traub G, Sampson KJ, Kass RS, Bohnen MS. Potassium Channels as Therapeutic Targets in Pulmonary Arterial Hypertension. Biomolecules. 12. PMID 36291551 DOI: 10.3390/biom12101341 |
0.393 |
|
| 2022 |
Chen L, Peng G, Comollo TW, Zou X, Sampson KJ, Larsson HP, Kass RS. Two small-molecule activators share similar effector sites in the KCNQ1 channel pore but have distinct effects on voltage sensor movements. Frontiers in Physiology. 13: 903050. PMID 35957984 DOI: 10.3389/fphys.2022.903050 |
0.847 |
|
| 2022 |
Comollo TW, Zou X, Zhang C, Kesters D, Hof T, Sampson KJ, Kass RS. Exploring mutation specific beta blocker pharmacology of the pathogenic late sodium channel current from patient-specific pluripotent stem cell myocytes derived from long QT syndrome mutation carriers. Channels (Austin, Tex.). 16: 173-184. PMID 35949058 DOI: 10.1080/19336950.2022.2106025 |
0.856 |
|
| 2021 |
Johnson M, Gomez-Galeno J, Ryan D, Okolotowicz K, McKeithan WL, Sampson KJ, Kass RS, Mercola M, Cashman JR. Human iPSC-derived Cardiomyocytes and Pyridyl-Phenyl Mexiletine Analogs. Bioorganic & Medicinal Chemistry Letters. 128162. PMID 34062251 DOI: 10.1016/j.bmcl.2021.128162 |
0.38 |
|
| 2021 |
Cashman JR, Ryan D, McKeithan WL, Okolotowicz K, Gomez-Galeno J, Johnson M, Sampson KJ, Kass RS, Pezhouman A, Karagueuzian HS, Mercola M. Antiarrhythmic Hit to Lead Refinement in a Dish Using Patient-Derived iPSC Cardiomyocytes. Journal of Medicinal Chemistry. PMID 33942619 DOI: 10.1021/acs.jmedchem.0c01545 |
0.386 |
|
| 2020 |
McKeithan WL, Feyen DAM, Bruyneel AAN, Okolotowicz KJ, Ryan DA, Sampson KJ, Potet F, Savchenko A, Gómez-Galeno J, Vu M, Serrano R, George AL, Kass RS, Cashman JR, Mercola M. Reengineering an Antiarrhythmic Drug Using Patient hiPSC Cardiomyocytes to Improve Therapeutic Potential and Reduce Toxicity. Cell Stem Cell. PMID 32931730 DOI: 10.1016/J.Stem.2020.08.003 |
0.45 |
|
| 2019 |
Shandell MA, Quejada JR, Yazawa M, Cornish VW, Kass RS. Detection of Na1.5 Conformational Change in Mammalian Cells Using the Noncanonical Amino Acid ANAP. Biophysical Journal. PMID 31521331 DOI: 10.1016/J.Bpj.2019.08.028 |
0.477 |
|
| 2019 |
Li Y, Hof T, Baldwin TA, Chen L, Kass RS, Dessauer CW. Regulation of I Potassium Current by Isoproterenol in Adult Cardiomyocytes Requires Type 9 Adenylyl Cyclase. Cells. 8. PMID 31461851 DOI: 10.3390/Cells8090981 |
0.376 |
|
| 2019 |
Wu X, Perez ME, Sampson KJ, Kass RS, Larsson PH. Determining Functional KCNQ1/KCNE1 Subunit Interactions in the KCNQ1/KCNE1 Channel Biophysical Journal. 116: 539a. DOI: 10.1016/J.Bpj.2018.11.2900 |
0.54 |
|
| 2017 |
Bohnen MS, Roman-Campos D, Terrenoire C, Jnani J, Sampson KJ, Chung WK, Kass RS. The Impact of Heterozygous KCNK3 Mutations Associated With Pulmonary Arterial Hypertension on Channel Function and Pharmacological Recovery. Journal of the American Heart Association. 6. PMID 28889099 DOI: 10.1161/Jaha.117.006465 |
0.456 |
|
| 2017 |
Barro-Soria R, Ramentol R, Liin SI, Perez ME, Kass RS, Larsson HP. KCNE1 and KCNE3 modulate KCNQ1 channels by affecting different gating transitions. Proceedings of the National Academy of Sciences of the United States of America. PMID 28808020 DOI: 10.1073/Pnas.1710335114 |
0.599 |
|
| 2017 |
Peng G, Barro-Soria R, Sampson KJ, Larsson HP, Kass RS. Gating mechanisms underlying deactivation slowing by two KCNQ1 atrial fibrillation mutations. Scientific Reports. 7: 45911. PMID 28383569 DOI: 10.1038/Srep45911 |
0.568 |
|
| 2017 |
Bohnen MS, Peng G, Robey SH, Terrenoire C, Iyer V, Sampson KJ, Kass RS. Molecular Pathophysiology of Congenital Long QT Syndrome. Physiological Reviews. 97: 89-134. PMID 27807201 DOI: 10.1152/Physrev.00008.2016 |
0.452 |
|
| 2016 |
Chen L, Sampson KJ, Kass RS. Cardiac Delayed Rectifier Potassium Channels in Health and Disease. Cardiac Electrophysiology Clinics. 8: 307-22. PMID 27261823 DOI: 10.1016/J.Ccep.2016.01.004 |
0.576 |
|
| 2016 |
Lorberbaum T, Sampson KJ, Woosley RL, Kass RS, Tatonetti NP. An Integrative Data Science Pipeline to Identify Novel Drug Interactions that Prolong the QT Interval. Drug Safety. PMID 26860921 DOI: 10.1007/S40264-016-0393-1 |
0.32 |
|
| 2015 |
Iyer V, Roman-Campos D, Sampson KJ, Kang G, Fishman GI, Kass RS. Purkinje Cells as Sources of Arrhythmias in Long QT Syndrome Type 3. Scientific Reports. 5: 13287. PMID 26289036 DOI: 10.1038/Srep13287 |
0.401 |
|
| 2015 |
Bohnen MS, Iyer V, Sampson KJ, Kass RS. Novel mechanism of transient outward potassium channel current regulation in the heart: implications for cardiac electrophysiology in health and disease. Circulation Research. 116: 1633-5. PMID 25953919 DOI: 10.1161/Circresaha.115.306438 |
0.551 |
|
| 2015 |
Clancy CE, Chen-Izu Y, Bers DM, Belardinelli L, Boyden PA, Csernoch L, Despa S, Fermini B, Hool LC, Izu L, Kass RS, Lederer WJ, Louch WE, Maack C, Matiazzi A, et al. Deranged sodium to sudden death. The Journal of Physiology. 593: 1331-45. PMID 25772289 DOI: 10.1113/Jphysiol.2014.281204 |
0.678 |
|
| 2015 |
Robey SH, Sampson KJ, Kass RS. Single-Channel Analysis of the Molecular Pharmacology of the Long QT Syndrome Variant 3 Biophysical Journal. 108: 584a-585a. DOI: 10.1016/J.Bpj.2014.11.3190 |
0.654 |
|
| 2015 |
Peng G, Sampson KJ, Barro-Soria R, Larsson HP, Kass RS. Two KCNQ1 Mutations Associated with Familial Atrial Fibrillation, S140G and V141M, Demonstrate Distinct Voltage Sensor Phenotypes Biophysical Journal. 108: 427a. DOI: 10.1016/J.Bpj.2014.11.2335 |
0.523 |
|
| 2015 |
Barro-Soria R, Peng G, Sampson KJ, Kass RS, Larsson HP. KCNE3 Stabilizes the Voltage Sensor S4 of KCNQ1 Channel, KCNE1 Uncouples S4 and the Gate Biophysical Journal. 108: 276a. DOI: 10.1016/J.Bpj.2014.11.1511 |
0.63 |
|
| 2014 |
Dvir M, Strulovich R, Sachyani D, Ben-Tal Cohen I, Haitin Y, Dessauer C, Pongs O, Kass R, Hirsch JA, Attali B. Long QT mutations at the interface between KCNQ1 helix C and KCNE1 disrupt I(KS) regulation by PKA and PIP₂. Journal of Cell Science. 127: 3943-55. PMID 25037568 DOI: 10.1242/Jcs.147033 |
0.551 |
|
| 2014 |
Iyer V, Sampson KJ, Kass RS. Modeling tissue- and mutation- specific electrophysiological effects in the long QT syndrome: role of the Purkinje fiber. Plos One. 9: e97720. PMID 24892747 DOI: 10.1371/Journal.Pone.0097720 |
0.458 |
|
| 2014 |
Barro-Soria R, Rebolledo S, Liin SI, Perez ME, Sampson KJ, Kass RS, Larsson HP. KCNE1 divides the voltage sensor movement in KCNQ1/KCNE1 channels into two steps. Nature Communications. 5: 3750. PMID 24769622 DOI: 10.1038/Ncomms4750 |
0.586 |
|
| 2014 |
Barro-Soria R, Rebolledo S, Liin SI, Perez ME, Sampson K, Kass RS, Larsson HP. KCNE1 Separates the Main Voltage Sensor Movement and Channel Opening in KCNQ1/KCNE1 Channels Biophysical Journal. 106: 142a. DOI: 10.1016/J.Bpj.2013.11.825 |
0.618 |
|
| 2013 |
Moreno JD, Yang PC, Bankston JR, Grandi E, Bers DM, Kass RS, Clancy CE. Ranolazine for congenital and acquired late INa-linked arrhythmias: in silico pharmacological screening. Circulation Research. 113: e50-61. PMID 23897695 DOI: 10.1161/Circresaha.113.301971 |
0.752 |
|
| 2013 |
Ma L, Roman-Campos D, Austin ED, Eyries M, Sampson KS, Soubrier F, Germain M, Trégouët DA, Borczuk A, Rosenzweig EB, Girerd B, Montani D, Humbert M, Loyd JE, Kass RS, et al. A novel channelopathy in pulmonary arterial hypertension. The New England Journal of Medicine. 369: 351-61. PMID 23883380 DOI: 10.1056/Nejmoa1211097 |
0.379 |
|
| 2013 |
Yu H, Lin Z, Mattmann ME, Zou B, Terrenoire C, Zhang H, Wu M, McManus OB, Kass RS, Lindsley CW, Hopkins CR, Li M. Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels. Proceedings of the National Academy of Sciences of the United States of America. 110: 8732-7. PMID 23650380 DOI: 10.1073/Pnas.1300684110 |
0.626 |
|
| 2013 |
Xiao L, Koopmann TT, Ördög B, Postema PG, Verkerk AO, Iyer V, Sampson KJ, Boink GJ, Mamarbachi MA, Varro A, Jordaens L, Res J, Kass RS, Wilde AA, Bezzina CR, et al. Unique cardiac Purkinje fiber transient outward current β-subunit composition: a potential molecular link to idiopathic ventricular fibrillation. Circulation Research. 112: 1310-22. PMID 23532596 DOI: 10.1161/Circresaha.112.300227 |
0.519 |
|
| 2013 |
Terrenoire C, Wang K, Tung KW, Chung WK, Pass RH, Lu JT, Jean JC, Omari A, Sampson KJ, Kotton DN, Keller G, Kass RS. Induced pluripotent stem cells used to reveal drug actions in a long QT syndrome family with complex genetics. The Journal of General Physiology. 141: 61-72. PMID 23277474 DOI: 10.1083/Jcb2001Oia3 |
0.568 |
|
| 2013 |
Barro-Soria R, Osteen JD, Sampson KJ, Perez ME, Kass RS, Larsson HP. Long QT Mutations and KCNE1 β-Subunit Modulate S4 Movement in KCNQ1 Channel Biophysical Journal. 104: 357a. DOI: 10.1016/J.Bpj.2012.11.1982 |
0.854 |
|
| 2013 |
Dvir M, Shaham D, Ben-Tal Cohen I, Strulovitz R, Haitin Y, Dessauer C, Kass R, Hirsch J, Attali B. The Distal Kcne1 C-Terminus is Crucial for Yotiao Mediated Pka-Dependent Phosphorylation of KCNQ1 Biophysical Journal. 104: 210a. DOI: 10.1016/J.Bpj.2012.11.1186 |
0.49 |
|
| 2013 |
Chen L, Terrenoire C, Kass RS. KCNQ1/KCNE1 Macromolecular Signaling Complex: Channel Microdomains and Human Disease Cardiac Electrophysiology: From Cell to Bedside: Sixth Edition. 115-120. DOI: 10.1016/B978-1-4557-2856-5.00011-X |
0.349 |
|
| 2012 |
Li Y, Chen L, Kass RS, Dessauer CW. The A-kinase anchoring protein Yotiao facilitates complex formation between adenylyl cyclase type 9 and the IKs potassium channel in heart. The Journal of Biological Chemistry. 287: 29815-24. PMID 22778270 DOI: 10.1074/Jbc.M112.380568 |
0.427 |
|
| 2012 |
Osteen JD, Barro-Soria R, Robey S, Sampson KJ, Kass RS, Larsson HP. Allosteric gating mechanism underlies the flexible gating of KCNQ1 potassium channels. Proceedings of the National Academy of Sciences of the United States of America. 109: 7103-8. PMID 22509038 DOI: 10.1073/Pnas.1201582109 |
0.831 |
|
| 2012 |
Glaaser IW, Osteen JD, Puckerin A, Sampson KJ, Jin X, Kass RS. Perturbation of sodium channel structure by an inherited Long QT Syndrome mutation. Nature Communications. 3: 706. PMID 22426227 DOI: 10.1038/Ncomms1717 |
0.844 |
|
| 2012 |
Wang M, Kass RS. Stoichiometry of the slow I(ks) potassium channel in human embryonic stem cell-derived myocytes. Pediatric Cardiology. 33: 938-42. PMID 22421958 DOI: 10.1007/s00246-012-0255-2 |
0.546 |
|
| 2012 |
Chan PJ, Osteen JD, Xiong D, Bohnen MS, Doshi D, Sampson KJ, Marx SO, Karlin A, Kass RS. Characterization of KCNQ1 atrial fibrillation mutations reveals distinct dependence on KCNE1. The Journal of General Physiology. 139: 135-44. PMID 22250012 DOI: 10.1085/Jgp.201110672 |
0.866 |
|
| 2012 |
Iyer V, Sampson K, Kass R. Computational Predictions of Tissue-Specific Consequences of Long QT Mutations: Role of the Purkinje Fiber Biophysical Journal. 102: 543a. DOI: 10.1016/J.Bpj.2011.11.2963 |
0.527 |
|
| 2012 |
Wang K, Terrenoire C, Sampson KJ, Lyer V, Chan Tung KW, Lu J, Chung W, Pass RH, Keller G, Kotton DN, Kass RS. Patient-Specific Inducible Pluripotent Stem Cells Reveal Mechanism of Personalized Therapy for an Inherited Cardiac Arrhythmia Biophysical Journal. 102: 539a. DOI: 10.1016/J.Bpj.2011.11.2947 |
0.512 |
|
| 2012 |
Liu M, Lardin H, Kass RS, Dudley SC. The Role of Channel PKA/PKC Sites in Metabolic Regulation of the Cardiac Na+ Channel Biophysical Journal. 102: 527a. DOI: 10.1016/J.BPJ.2011.11.2881 |
0.563 |
|
| 2012 |
Osteen JD, Robey SH, Barro R, Rebolledo S, Sampson KJ, Larsson HP, Kass RS. Allosteric Properties of KCNQ1 (Kv7.1) Channel Gating Detected by Voltage Clamp Fluorometry Biophysical Journal. 102: 332a. DOI: 10.1016/J.Bpj.2011.11.1819 |
0.836 |
|
| 2012 |
Barro-Soria R, Osteen JD, Sampson KJ, Perez ME, Kass RS, Larsson P. Activation of Voltage Sensing Domains during KCNQ1 Channel Opening: Concerted or Independent? Biophysical Journal. 102: 332a. DOI: 10.1016/J.Bpj.2011.11.1817 |
0.871 |
|
| 2012 |
Robey S, Sampson KJ, Kass RS. Ion channels as targets for drugs Cell Physiology Source Book. 525-534. DOI: 10.1016/B978-0-12-387738-3.00029-9 |
0.337 |
|
| 2011 |
Wang K, Terrenoire C, Sampson KJ, Iyer V, Osteen JD, Lu J, Keller G, Kotton DN, Kass RS. Biophysical properties of slow potassium channels in human embryonic stem cell derived cardiomyocytes implicate subunit stoichiometry. The Journal of Physiology. 589: 6093-104. PMID 22025662 DOI: 10.1113/Jphysiol.2011.220863 |
0.848 |
|
| 2011 |
Chen L, Kass RS. A-kinase anchoring protein 9 and IKs channel regulation. Journal of Cardiovascular Pharmacology. 58: 459-13. PMID 21885989 DOI: 10.1097/FJC.0b013e318232c80c |
0.564 |
|
| 2011 |
Moreno JD, Zhu ZI, Yang PC, Bankston JR, Jeng MT, Kang C, Wang L, Bayer JD, Christini DJ, Trayanova NA, Ripplinger CM, Kass RS, Clancy CE. A computational model to predict the effects of class I anti-arrhythmic drugs on ventricular rhythms. Science Translational Medicine. 3: 98ra83. PMID 21885405 DOI: 10.1126/Scitranslmed.3002588 |
0.754 |
|
| 2011 |
Quinn TA, Granite S, Allessie MA, Antzelevitch C, Bollensdorff C, Bub G, Burton RA, Cerbai E, Chen PS, Delmar M, Difrancesco D, Earm YE, Efimov IR, Egger M, Entcheva E, ... ... Kass RS, et al. Minimum Information about a Cardiac Electrophysiology Experiment (MICEE): standardised reporting for model reproducibility, interoperability, and data sharing. Progress in Biophysics and Molecular Biology. 107: 4-10. PMID 21745496 DOI: 10.1016/J.Pbiomolbio.2011.07.001 |
0.312 |
|
| 2011 |
Chandrasekhar KD, Lvov A, Terrenoire C, Gao GY, Kass RS, Kobertz WR. O-glycosylation of the cardiac I(Ks) complex. The Journal of Physiology. 589: 3721-30. PMID 21669976 DOI: 10.1113/Jphysiol.2011.211284 |
0.354 |
|
| 2011 |
Christian F, Szaszák M, Friedl S, Drewianka S, Lorenz D, Goncalves A, Furkert J, Vargas C, Schmieder P, Götz F, Zühlke K, Moutty M, Göttert H, Joshi M, Reif B, ... ... Kass R, et al. Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytes. The Journal of Biological Chemistry. 286: 9079-96. PMID 21177871 DOI: 10.1074/Jbc.M110.160614 |
0.366 |
|
| 2011 |
Osteen JD, Gonzalez C, Sampson KJ, Iyer V, Rebolledo S, Larsson HP, Kass RS. A novel Beta Subunit Mechanism in a Critical Heart K Channel: KCNE1 Alters the Voltage Sensor Movements Necessary to Open the KCNQ1 Channel Gate Biophysical Journal. 100: 29a-30a. DOI: 10.1016/J.Bpj.2010.12.365 |
0.85 |
|
| 2011 |
Glaaser IW, Osteen JD, Puckerin A, Kass RS. Mapping the Structure of the Cardiac Voltage-Gated Sodium Channel (Nav1.5) C-Terminus: Implications of An Lqt3 Mutant Biophysical Journal. 100: 15a. DOI: 10.1016/J.Bpj.2010.12.293 |
0.83 |
|
| 2011 |
Wang K, Terrenoire C, Sampson KJ, Osteen JD, Lu J, Gagliardi M, Keller G, Kass RS. Biophysical Characterization of Iks Channels in Cardiomyocytes Derived from Human Embryonic Stem Cells Reveals Insights Into Stoichiometry of KCNQ1-KCNE1 Complex Biophysical Journal. 100: 439a. DOI: 10.1016/J.Bpj.2010.12.2588 |
0.839 |
|
| 2011 |
Heath B, Gingrich K, Kass RS. Ion Channels in the Heart: Cellular and Molecular Properties of Cardiac Na, Ca, and K Channels Comprehensive Physiology. DOI: 10.1002/Cphy.Cp020114 |
0.611 |
|
| 2010 |
Osteen JD, Gonzalez C, Sampson KJ, Iyer V, Rebolledo S, Larsson HP, Kass RS. KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate. Proceedings of the National Academy of Sciences of the United States of America. 107: 22710-5. PMID 21149716 DOI: 10.1073/Pnas.1016300108 |
0.854 |
|
| 2010 |
Osteen JD, Sampson KJ, Kass RS. The cardiac IKs channel, complex indeed. Proceedings of the National Academy of Sciences of the United States of America. 107: 18751-2. PMID 20974964 DOI: 10.1073/Pnas.1014150107 |
0.857 |
|
| 2010 |
Sampson KJ, Kass RS. Location, location, regulation: a novel role for β-spectrin in the heart. The Journal of Clinical Investigation. 120: 3434-7. PMID 20877007 DOI: 10.1172/Jci44810 |
0.463 |
|
| 2010 |
Sampson KJ, Iyer V, Marks AR, Kass RS. A computational model of Purkinje fibre single cell electrophysiology: implications for the long QT syndrome. The Journal of Physiology. 588: 2643-55. PMID 20498233 DOI: 10.1113/Jphysiol.2010.187328 |
0.521 |
|
| 2010 |
Lu JT, Kass RS. Recent progress in congenital long QT syndrome. Current Opinion in Cardiology. 25: 216-21. PMID 20224391 DOI: 10.1097/HCO.0b013e32833846b3 |
0.434 |
|
| 2010 |
Sampson KJ, Kass RS. Molecular mechanisms of adrenergic stimulation in the heart. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 7: 1151-3. PMID 20156590 DOI: 10.1016/J.Hrthm.2010.02.013 |
0.473 |
|
| 2010 |
Bankston JR, Kass RS. Molecular determinants of local anesthetic action of beta-blocking drugs: Implications for therapeutic management of long QT syndrome variant 3. Journal of Molecular and Cellular Cardiology. 48: 246-53. PMID 19481549 DOI: 10.1016/J.Yjmcc.2009.05.012 |
0.823 |
|
| 2010 |
Chan P, Osteen JD, Doshi D, Marx SO, Karlin A, Kass RS. Neighboring Alpha-Subunit (KCNQ1) Mutations with a Gain-of-Function IKs Phenotype Show Differential Dependence on Presence of Beta-Subunit (KCNE1) Biophysical Journal. 98: 121a. DOI: 10.1016/J.Bpj.2009.12.659 |
0.875 |
|
| 2010 |
Terrenoire C, Wang GK, Adler E, Kaplan AD, Sampson K, Lu J, Kass RS. KCNQ1/KCNE1 K+ Channels Associated with Long QT Syndrome are Expressed in Early Stage Human Embryonic Stem Cell-Derived Cardiomyocytes Biophysical Journal. 98: 335a. DOI: 10.1016/J.Bpj.2009.12.1817 |
0.603 |
|
| 2010 |
Moreno JD, Bankston JR, Kass RS, Clancy C. Cardiac Dynamics In-Silico: Pharmacological Targeting of Long QT3 Syndrome Biophysical Journal. 98: 8a. DOI: 10.1016/J.Bpj.2009.12.050 |
0.761 |
|
| 2009 |
Lindegger N, Hagen BM, Marks AR, Lederer WJ, Kass RS. Diastolic transient inward current in long QT syndrome type 3 is caused by Ca2+ overload and inhibited by ranolazine. Journal of Molecular and Cellular Cardiology. 47: 326-34. PMID 19371746 DOI: 10.1016/J.Yjmcc.2009.04.003 |
0.627 |
|
| 2009 |
Terrenoire C, Houslay MD, Baillie GS, Kass RS. The cardiac IKs potassium channel macromolecular complex includes the phosphodiesterase PDE4D3. The Journal of Biological Chemistry. 284: 9140-6. PMID 19218243 DOI: 10.1074/jbc.M805366200 |
0.566 |
|
| 2009 |
Chung DY, Chan PJ, Bankston JR, Yang L, Liu G, Marx SO, Karlin A, Kass RS. Location of KCNE1 relative to KCNQ1 in the I(KS) potassium channel by disulfide cross-linking of substituted cysteines. Proceedings of the National Academy of Sciences of the United States of America. 106: 743-8. PMID 19131515 DOI: 10.1073/Pnas.0811897106 |
0.758 |
|
| 2009 |
Kurokawa J, Bankston JR, Kaihara A, Chen L, Furukawa T, Kass RS. KCNE variants reveal a critical role of the beta subunit carboxyl terminus in PKA-dependent regulation of the IKs potassium channel. Channels (Austin, Tex.). 3: 16-24. PMID 19077539 DOI: 10.4161/Chan.3.1.7387 |
0.85 |
|
| 2008 |
Bankston JR, Kass RS. Ion channels: The voltage-sensor quartet. Nature. 456: 183-5. PMID 19005542 DOI: 10.1038/456183A |
0.796 |
|
| 2008 |
Kass RS, Lindegger N, Hagen B, Lederer WJ. Another calcium paradox in heart failure. Journal of Molecular and Cellular Cardiology. 45: 28-31. PMID 18504047 DOI: 10.1016/j.yjmcc.2008.04.001 |
0.539 |
|
| 2008 |
Lehnart SE, Mongillo M, Bellinger A, Lindegger N, Chen BX, Hsueh W, Reiken S, Wronska A, Drew LJ, Ward CW, Lederer WJ, Kass RS, Morley G, Marks AR. Leaky Ca2+ release channel/ryanodine receptor 2 causes seizures and sudden cardiac death in mice. The Journal of Clinical Investigation. 118: 2230-45. PMID 18483626 DOI: 10.1172/Jci35346 |
0.713 |
|
| 2008 |
Nicolas CS, Park KH, El Harchi A, Camonis J, Kass RS, Escande D, Mérot J, Loussouarn G, Le Bouffant F, Baró I. IKs response to protein kinase A-dependent KCNQ1 phosphorylation requires direct interaction with microtubules. Cardiovascular Research. 79: 427-35. PMID 18390900 DOI: 10.1093/cvr/cvn085 |
0.529 |
|
| 2008 |
Holland KD, Kearney JA, Glauser TA, Buck G, Keddache M, Blankston JR, Glaaser IW, Kass RS, Meisler MH. Mutation of sodium channel SCN3A in a patient with cryptogenic pediatric partial epilepsy. Neuroscience Letters. 433: 65-70. PMID 18242854 DOI: 10.1016/J.Neulet.2007.12.064 |
0.787 |
|
| 2008 |
Sampson KJ, Terrenoire C, Cervantes DO, Kaba RA, Peters NS, Kass RS. Adrenergic regulation of a key cardiac potassium channel can contribute to atrial fibrillation: evidence from an I Ks transgenic mouse. The Journal of Physiology. 586: 627-37. PMID 18006587 DOI: 10.1113/Jphysiol.2007.141333 |
0.565 |
|
| 2007 |
Bankston JR, Sampson KJ, Kateriya S, Glaaser IW, Malito DL, Chung WK, Kass RS. A novel LQT-3 mutation disrupts an inactivation gate complex with distinct rate-dependent phenotypic consequences. Channels (Austin, Tex.). 1: 273-80. PMID 18708744 DOI: 10.4161/Chan.4956 |
0.865 |
|
| 2007 |
Chen L, Marquardt ML, Tester DJ, Sampson KJ, Ackerman MJ, Kass RS. Mutation of an A-kinase-anchoring protein causes long-QT syndrome. Proceedings of the National Academy of Sciences of the United States of America. 104: 20990-5. PMID 18093912 DOI: 10.1073/Pnas.0710527105 |
0.554 |
|
| 2007 |
Bankston JR, Yue M, Chung W, Spyres M, Pass RH, Silver E, Sampson KJ, Kass RS. A novel and lethal de novo LQT-3 mutation in a newborn with distinct molecular pharmacology and therapeutic response. Plos One. 2: e1258. PMID 18060054 DOI: 10.1371/Journal.Pone.0001258 |
0.821 |
|
| 2007 |
Bankston JR, Kass RS. Fading sodium channels in failing hearts. Circulation Research. 101: 1073-4. PMID 18040022 DOI: 10.1161/Circresaha.107.165597 |
0.786 |
|
| 2007 |
Terrenoire C, Simhaee D, Kass RS. Role of sodium channels in propagation in heart muscle: how subtle genetic alterations result in major arrhythmic disorders. Journal of Cardiovascular Electrophysiology. 18: 900-5. PMID 17504259 DOI: 10.1111/j.1540-8167.2007.00838.x |
0.549 |
|
| 2007 |
Seebohm G, Strutz-Seebohm N, Birkin R, Dell G, Bucci C, Spinosa MR, Baltaev R, Mack AF, Korniychuk G, Choudhury A, Marks D, Pagano RE, Attali B, Pfeufer A, Kass RS, et al. Regulation of endocytic recycling of KCNQ1/KCNE1 potassium channels. Circulation Research. 100: 686-92. PMID 17293474 DOI: 10.1161/01.Res.0000260250.83824.8F |
0.492 |
|
| 2007 |
Kass RS, Cormier JW, Glaaser IW. The Cardiac Sodium-Channel Carboxy Terminus: Predicted and Detected Structure Provide a Novel Target For Antiarrhythmic Drugs Development New Arrhythmia Technologies. 36-47. DOI: 10.1002/9780470988725.ch4 |
0.825 |
|
| 2006 |
Fredj S, Lindegger N, Sampson KJ, Carmeliet P, Kass RS. Altered Na+ channels promote pause-induced spontaneous diastolic activity in long QT syndrome type 3 myocytes. Circulation Research. 99: 1225-32. PMID 17082480 DOI: 10.1161/01.Res.0000251305.25604.B0 |
0.548 |
|
| 2006 |
Glaaser IW, Bankston JR, Liu H, Tateyama M, Kass RS. A carboxyl-terminal hydrophobic interface is critical to sodium channel function. Relevance to inherited disorders. The Journal of Biological Chemistry. 281: 24015-23. PMID 16798729 DOI: 10.1074/Jbc.M605473200 |
0.864 |
|
| 2006 |
Kass RS. Sodium channel inactivation in heart: a novel role of the carboxy-terminal domain. Journal of Cardiovascular Electrophysiology. 17: S21-S25. PMID 16686678 DOI: 10.1111/j.1540-8167.2006.00381.x |
0.662 |
|
| 2006 |
Lehnart SE, Terrenoire C, Reiken S, Wehrens XH, Song LS, Tillman EJ, Mancarella S, Coromilas J, Lederer WJ, Kass RS, Marks AR. Stabilization of cardiac ryanodine receptor prevents intracellular calcium leak and arrhythmias. Proceedings of the National Academy of Sciences of the United States of America. 103: 7906-10. PMID 16672364 DOI: 10.1073/Pnas.0602133103 |
0.649 |
|
| 2006 |
Chen L, Kass RS. Dual roles of the A kinase-anchoring protein Yotiao in the modulation of a cardiac potassium channel: a passive adaptor versus an active regulator. European Journal of Cell Biology. 85: 623-6. PMID 16647783 DOI: 10.1016/j.ejcb.2006.03.002 |
0.548 |
|
| 2006 |
Kass RS, Moss AJ. Mutation-specific pharmacology of the long QT syndrome. Handbook of Experimental Pharmacology. 287-304. PMID 16610349 DOI: 10.1007/3-540-29715-4-11 |
0.443 |
|
| 2006 |
Fredj S, Sampson KJ, Liu H, Kass RS. Molecular basis of ranolazine block of LQT-3 mutant sodium channels: evidence for site of action. British Journal of Pharmacology. 148: 16-24. PMID 16520744 DOI: 10.1038/Sj.Bjp.0706709 |
0.638 |
|
| 2005 |
Nerbonne JM, Kass RS. Molecular physiology of cardiac repolarization. Physiological Reviews. 85: 1205-53. PMID 16183911 DOI: 10.1152/Physrev.00002.2005 |
0.623 |
|
| 2005 |
Moss AJ, Kass RS. Long QT syndrome: from channels to cardiac arrhythmias. The Journal of Clinical Investigation. 115: 2018-24. PMID 16075042 DOI: 10.1172/JCI25537 |
0.514 |
|
| 2005 |
Kass RS. The channelopathies: novel insights into molecular and genetic mechanisms of human disease. The Journal of Clinical Investigation. 115: 1986-9. PMID 16075038 DOI: 10.1172/JCI26011 |
0.5 |
|
| 2005 |
Shushi L, Kerem B, Goldmit M, Peretz A, Attali B, Medina A, Towbin JA, Kurokawa J, Kass RS, Benhorin J. Clinical, genetic, and electrophysiologic characteristics of a new PAS-domain HERG mutation (M124R) causing Long QT syndrome. Annals of Noninvasive Electrocardiology : the Official Journal of the International Society For Holter and Noninvasive Electrocardiology, Inc. 10: 334-41. PMID 16029385 DOI: 10.1111/J.1542-474X.2005.00643.X |
0.669 |
|
| 2005 |
Chen L, Kurokawa J, Kass RS. Phosphorylation of the A-kinase-anchoring protein Yotiao contributes to protein kinase A regulation of a heart potassium channel. The Journal of Biological Chemistry. 280: 31347-52. PMID 16002409 DOI: 10.1074/Jbc.M505191200 |
0.668 |
|
| 2005 |
Abriel H, Kass RS. Regulation of the voltage-gated cardiac sodium channel Nav1.5 by interacting proteins. Trends in Cardiovascular Medicine. 15: 35-40. PMID 15795161 DOI: 10.1016/J.Tcm.2005.01.001 |
0.694 |
|
| 2005 |
Terrenoire C, Clancy CE, Cormier JW, Sampson KJ, Kass RS. Autonomic control of cardiac action potentials: role of potassium channel kinetics in response to sympathetic stimulation. Circulation Research. 96: e25-34. PMID 15731462 DOI: 10.1161/01.Res.0000160555.58046.9A |
0.811 |
|
| 2005 |
Clancy CE, Kass RS. Inherited and acquired vulnerability to ventricular arrhythmias: cardiac Na+ and K+ channels. Physiological Reviews. 85: 33-47. PMID 15618477 DOI: 10.1152/physrev.00005.2004 |
0.527 |
|
| 2005 |
Nerbonne JM, Kass RS. Molecular physiology of ion channels that control cardiac repolarization Cardiac Safety of Noncardiac Drugs: Practical Guidelines For Clinical Research and Drug Development. 13-36. DOI: 10.1007/978-1-59259-884-7_2 |
0.422 |
|
| 2004 |
Rossenbacker T, Carroll SJ, Liu H, Kuipéri C, de Ravel TJ, Devriendt K, Carmeliet P, Kass RS, Heidbüchel H. Novel pore mutation in SCN5A manifests as a spectrum of phenotypes ranging from atrial flutter, conduction disease, and Brugada syndrome to sudden cardiac death. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 1: 610-5. PMID 15851228 DOI: 10.1016/j.hrthm.2004.07.001 |
0.438 |
|
| 2004 |
Kurokawa J, Motoike HK, Rao J, Kass RS. Regulatory actions of the A-kinase anchoring protein Yotiao on a heart potassium channel downstream of PKA phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 101: 16374-8. PMID 15528278 DOI: 10.1073/Pnas.0405583101 |
0.757 |
|
| 2004 |
Kim J, Ghosh S, Liu H, Tateyama M, Kass RS, Pitt GS. Calmodulin mediates Ca2+ sensitivity of sodium channels. The Journal of Biological Chemistry. 279: 45004-12. PMID 15316014 DOI: 10.1074/jbc.M407286200 |
0.495 |
|
| 2004 |
Dilly KW, Kurokawa J, Terrenoire C, Reiken S, Lederer WJ, Marks AR, Kass RS. Overexpression of beta2-adrenergic receptors cAMP-dependent protein kinase phosphorylates and modulates slow delayed rectifier potassium channels expressed in murine heart: evidence for receptor/channel co-localization. The Journal of Biological Chemistry. 279: 40778-87. PMID 15272004 DOI: 10.1074/Jbc.M406010200 |
0.751 |
|
| 2004 |
Kass RS. Sodium channel inactivation goes with the flow. The Journal of General Physiology. 124: 7-8. PMID 15226362 DOI: 10.1085/jgp.200409123 |
0.519 |
|
| 2004 |
van Bemmelen MX, Rougier JS, Gavillet B, Apothéloz F, Daidié D, Tateyama M, Rivolta I, Thomas MA, Kass RS, Staub O, Abriel H. Cardiac voltage-gated sodium channel Nav1.5 is regulated by Nedd4-2 mediated ubiquitination. Circulation Research. 95: 284-91. PMID 15217910 DOI: 10.1161/01.Res.0000136816.05109.89 |
0.83 |
|
| 2004 |
Clancy CE, Kass RS. Theoretical investigation of the neuronal Na+ channel SCN1A: abnormal gating and epilepsy. Biophysical Journal. 86: 2606-14. PMID 15041696 DOI: 10.1016/S0006-3495(04)74315-5 |
0.51 |
|
| 2004 |
Tateyama M, Liu H, Yang AS, Cormier JW, Kass RS. Structural effects of an LQT-3 mutation on heart Na+ channel gating. Biophysical Journal. 86: 1843-51. PMID 14990510 DOI: 10.1016/S0006-3495(04)74251-4 |
0.833 |
|
| 2004 |
Motoike HK, Liu H, Glaaser IW, Yang AS, Tateyama M, Kass RS. The Na+ channel inactivation gate is a molecular complex: a novel role of the COOH-terminal domain. The Journal of General Physiology. 123: 155-65. PMID 14744988 DOI: 10.1085/Jgp.200308929 |
0.836 |
|
| 2004 |
Carroll SJ, Kurokawa J, Kass RS. KCNQ1/KCNE1 Macromolecular Signaling Complex: Channel Microdomains and Human Disease Cardiac Electrophysiology: Fourth Edition. 143-149. DOI: 10.1016/B0-7216-0323-8/50020-8 |
0.349 |
|
| 2003 |
Glaaser IW, Kass RS, Clancy CE. Mechanisms of genetic arrhythmias: from DNA to ECG. Progress in Cardiovascular Diseases. 46: 259-70. PMID 14685943 DOI: 10.1016/S0033-0620(03)00073-2 |
0.748 |
|
| 2003 |
Tateyama M, Rivolta I, Clancy CE, Kass RS. Modulation of cardiac sodium channel gating by protein kinase A can be altered by disease-linked mutation. The Journal of Biological Chemistry. 278: 46718-26. PMID 14500710 DOI: 10.1074/jbc.M308977200 |
0.616 |
|
| 2003 |
Kass RS, Moss AJ. Long QT syndrome: novel insights into the mechanisms of cardiac arrhythmias. The Journal of Clinical Investigation. 112: 810-5. PMID 12975462 DOI: 10.1172/JCI19844 |
0.391 |
|
| 2003 |
Liu H, Clancy CE, Cormier JW, Kass RS. Mutations in cardiac sodium channels: Clinical implications American Journal of Pharmacogenomics. 3: 173-179. PMID 12814325 DOI: 10.2165/00129785-200303030-00003 |
0.857 |
|
| 2003 |
Tateyama M, Kurokawa J, Terrenoire C, Rivolta I, Kass RS. Stimulation of protein kinase C inhibits bursting in disease-linked mutant human cardiac sodium channels. Circulation. 107: 3216-22. PMID 12796143 DOI: 10.1161/01.Cir.0000070936.65183.97 |
0.787 |
|
| 2003 |
Clancy CE, Tateyama M, Liu H, Wehrens XH, Kass RS. Non-equilibrium gating in cardiac Na+ channels: an original mechanism of arrhythmia. Circulation. 107: 2233-7. PMID 12695286 DOI: 10.1161/01.CIR.0000069273.51375.BD |
0.653 |
|
| 2003 |
Wehrens XH, Rossenbacker T, Jongbloed RJ, Gewillig M, Heidbüchel H, Doevendans PA, Vos MA, Wellens HJ, Kass RS. A novel mutation L619F in the cardiac Na+ channel SCN5A associated with long-QT syndrome (LQT3): a role for the I-II linker in inactivation gating. Human Mutation. 21: 552. PMID 12673799 DOI: 10.1002/humu.9136 |
0.623 |
|
| 2003 |
Liu H, Atkins J, Kass RS. Common molecular determinants of flecainide and lidocaine block of heart Na+ channels: evidence from experiments with neutral and quaternary flecainide analogues. The Journal of General Physiology. 121: 199-214. PMID 12601084 DOI: 10.1085/Jgp.20028723 |
0.578 |
|
| 2003 |
Kass RS, Kurokawa J, Marx SO, Marks AR. Leucine/isoleucine zipper coordination of ion channel macromolecular signaling complexes in the heart. Roles in inherited arrhythmias. Trends in Cardiovascular Medicine. 13: 52-6. PMID 12586439 DOI: 10.1016/S1050-1738(02)00211-6 |
0.746 |
|
| 2003 |
Kurokawa J, Chen L, Kass RS. Requirement of subunit expression for cAMP-mediated regulation of a heart potassium channel. Proceedings of the National Academy of Sciences of the United States of America. 100: 2122-7. PMID 12566567 DOI: 10.1073/Pnas.0434935100 |
0.736 |
|
| 2003 |
Clancy CE, Kurokawa J, Tateyama M, Wehrens XH, Kass RS. K+ channel structure-activity relationships and mechanisms of drug-induced QT prolongation. Annual Review of Pharmacology and Toxicology. 43: 441-61. PMID 12540747 DOI: 10.1146/Annurev.Pharmtox.43.100901.140245 |
0.667 |
|
| 2003 |
Chiello Tracy C, Cabo C, Coromilas J, Kurokawa J, Kass RS, Wit AL. Electrophysiological consequences of human IKs channel expression in adult murine heart. American Journal of Physiology. Heart and Circulatory Physiology. 284: H168-75. PMID 12388269 DOI: 10.1152/Ajpheart.00661.2002 |
0.737 |
|
| 2002 |
Clancy CE, Tateyama M, Kass RS. Insights into the molecular mechanisms of bradycardia-triggered arrhythmias in long QT-3 syndrome. The Journal of Clinical Investigation. 110: 1251-62. PMID 12417563 DOI: 10.1172/JCI15928 |
0.624 |
|
| 2002 |
Wilde AA, Antzelevitch C, Borggrefe M, Brugada J, Brugada R, Brugada P, Corrado D, Hauer RN, Kass RS, Nademanee K, Priori SG, Towbin JA. Proposed diagnostic criteria for the Brugada syndrome: consensus report. Circulation. 106: 2514-9. PMID 12417552 DOI: 10.1161/01.CIR.0000034169.45752.4A |
0.403 |
|
| 2002 |
Clancy CE, Kass RS. Defective cardiac ion channels: from mutations to clinical syndromes. The Journal of Clinical Investigation. 110: 1075-7. PMID 12393842 DOI: 10.1172/JCI16945 |
0.599 |
|
| 2002 |
Rivolta I, Clancy CE, Tateyama M, Liu H, Priori SG, Kass RS. A novel SCN5A mutation associated with long QT-3: altered inactivation kinetics and channel dysfunction. Physiological Genomics. 10: 191-7. PMID 12209021 DOI: 10.1152/physiolgenomics.00039.2002 |
0.652 |
|
| 2002 |
Splawski I, Timothy KW, Tateyama M, Clancy CE, Malhotra A, Beggs AH, Cappuccio FP, Sagnella GA, Kass RS, Keating MT. Variant of SCN5A sodium channel implicated in risk of cardiac arrhythmia. Science (New York, N.Y.). 297: 1333-6. PMID 12193783 DOI: 10.1126/Science.1073569 |
0.479 |
|
| 2002 |
Liu H, Tateyama M, Clancy CE, Abriel H, Kass RS. Channel openings are necessary but not sufficient for use-dependent block of cardiac Na(+) channels by flecainide: evidence from the analysis of disease-linked mutations. The Journal of General Physiology. 120: 39-51. PMID 12084774 DOI: 10.1085/Jgp.20028558 |
0.784 |
|
| 2002 |
Benhorin J, Moss AJ, Bak M, Zareba W, Kaufman ES, Kerem B, Towbin JA, Priori S, Kass RS, Attali B, Brown AM, Ficker E. Variable expression of long QT syndrome among gene carriers from families with five different HERG mutations. Annals of Noninvasive Electrocardiology : the Official Journal of the International Society For Holter and Noninvasive Electrocardiology, Inc. 7: 40-6. PMID 11844290 DOI: 10.1111/J.1542-474X.2001.Tb00137.X |
0.426 |
|
| 2002 |
Marx SO, Kurokawa J, Reiken S, Motoike H, D'Armiento J, Marks AR, Kass RS. Requirement of a macromolecular signaling complex for beta adrenergic receptor modulation of the KCNQ1-KCNE1 potassium channel. Science (New York, N.Y.). 295: 496-9. PMID 11799244 DOI: 10.1126/Science.1066843 |
0.747 |
|
| 2002 |
Cormier JW, Rivolta I, Tateyama M, Yang AS, Kass RS. Secondary structure of the human cardiac Na+ channel C terminus: evidence for a role of helical structures in modulation of channel inactivation. The Journal of Biological Chemistry. 277: 9233-41. PMID 11741959 DOI: 10.1074/Jbc.M110204200 |
0.853 |
|
| 2001 |
Rivolta I, Abriel H, Tateyama M, Liu H, Memmi M, Vardas P, Napolitano C, Priori SG, Kass RS. Inherited Brugada and long QT-3 syndrome mutations of a single residue of the cardiac sodium channel confer distinct channel and clinical phenotypes. The Journal of Biological Chemistry. 276: 30623-30. PMID 11410597 DOI: 10.1074/Jbc.M104471200 |
0.77 |
|
| 2001 |
Kurokawa J, Abriel H, Kass RS. Molecular basis of the delayed rectifier current I(ks)in heart. Journal of Molecular and Cellular Cardiology. 33: 873-82. PMID 11343411 DOI: 10.1006/Jmcc.2001.1377 |
0.8 |
|
| 2001 |
Abriel H, Cabo C, Wehrens XH, Rivolta I, Motoike HK, Memmi M, Napolitano C, Priori SG, Kass RS. Novel arrhythmogenic mechanism revealed by a long-QT syndrome mutation in the cardiac Na(+) channel. Circulation Research. 88: 740-5. PMID 11304498 DOI: 10.1161/Hh0701.089668 |
0.79 |
|
| 2001 |
Dhar Malhotra J, Chen C, Rivolta I, Abriel H, Malhotra R, Mattei LN, Brosius FC, Kass RS, Isom LL. Characterization of sodium channel alpha- and beta-subunits in rat and mouse cardiac myocytes. Circulation. 103: 1303-10. PMID 11238277 DOI: 10.1161/01.Cir.103.9.1303 |
0.653 |
|
| 2001 |
Kurokawa J, Motoike HK, Kass RS. TEA(+)-sensitive KCNQ1 constructs reveal pore-independent access to KCNE1 in assembled I(Ks) channels. The Journal of General Physiology. 117: 43-52. PMID 11134230 DOI: 10.1085/Jgp.117.1.43 |
0.779 |
|
| 2000 |
Kass RS, Cabo C. Channel structure and drug-induced cardiac arrhythmias. Proceedings of the National Academy of Sciences of the United States of America. 97: 11683-4. PMID 11050193 DOI: 10.1073/Pnas.97.22.11683 |
0.462 |
|
| 2000 |
Abriel H, Wehrens XH, Benhorin J, Kerem B, Kass RS. Molecular pharmacology of the sodium channel mutation D1790G linked to the long-QT syndrome. Circulation. 102: 921-5. PMID 10952963 DOI: 10.1161/01.Cir.102.8.921 |
0.766 |
|
| 2000 |
Wehrens XH, Abriel H, Cabo C, Benhorin J, Kass RS. Arrhythmogenic mechanism of an LQT-3 mutation of the human heart Na(+) channel alpha-subunit: A computational analysis. Circulation. 102: 584-90. PMID 10920073 DOI: 10.1161/01.Cir.102.5.584 |
0.788 |
|
| 2000 |
Abriel H, Motoike H, Kass RS. KChAP: a novel chaperone for specific K(+) channels key to repolarization of the cardiac action potential. Focus on "KChAP as a chaperone for specific K(+) channels". American Journal of Physiology. Cell Physiology. 278: C863-4. PMID 10794658 DOI: 10.1152/Ajpcell.2000.278.5.C863 |
0.727 |
|
| 2000 |
Doevendans PA, Kubalak SW, An RH, Becker DK, Chien KR, Kass RS. Differentiation of cardiomyocytes in floating embryoid bodies is comparable to fetal cardiomyocytes. Journal of Molecular and Cellular Cardiology. 32: 839-51. PMID 10775488 DOI: 10.1006/Jmcc.2000.1128 |
0.364 |
|
| 2000 |
Benhorin J, Taub R, Goldmit M, Kerem B, Kass RS, Windman I, Medina A. Effects of flecainide in patients with new SCN5A mutation: mutation-specific therapy for long-QT syndrome? Circulation. 101: 1698-706. PMID 10758053 DOI: 10.1161/01.Cir.101.14.1698 |
0.471 |
|
| 1999 |
Lacinová L, An RH, Xia J, Ito H, Klugbauer N, Triggle D, Hofmann F, Kass RS. Distinctions in the molecular determinants of charged and neutral dihydropyridine block of L-type calcium channels. The Journal of Pharmacology and Experimental Therapeutics. 289: 1472-9. PMID 10336541 |
0.511 |
|
| 1999 |
An R, Heath BM, Higgins JP, Koch WJ, Lefkowitz RJ, Kass RS. Beta2-adrenergic receptor overexpression in the developing mouse heart: evidence for targeted modulation of ion channels. The Journal of Physiology. 516: 19-30. PMID 10066919 DOI: 10.1111/J.1469-7793.1999.019Aa.X |
0.538 |
|
| 1999 |
An RH, Heath BM, Higgins JP, Koch WJ, Leflcowitz RJ, Kass RS. β-drenergic receptor overexpression in the developing mouse heart: Evidence for targeted modulation of ion channels Journal of Physiology. 516: 19-30. |
0.403 |
|
| 1998 |
Wang W, Xia J, Kass RS. MinK-KvLQT1 fusion proteins, evidence for multiple stoichiometries of the assembled IsK channel. The Journal of Biological Chemistry. 273: 34069-74. PMID 9852064 DOI: 10.1074/jbc.273.51.34069 |
0.622 |
|
| 1998 |
Heath BM, Xia J, Dong E, An RH, Brooks A, Liang C, Federoff HJ, Kass RS. Overexpression of nerve growth factor in the heart alters ion channel activity and beta-adrenergic signalling in an adult transgenic mouse. The Journal of Physiology. 512: 779-91. PMID 9769421 DOI: 10.1111/j.1469-7793.1998.779bd.x |
0.389 |
|
| 1998 |
An RH, Wang XL, Kerem B, Benhorin J, Medina A, Goldmit M, Kass RS. Novel LQT-3 mutation affects Na+ channel activity through interactions between alpha- and beta1-subunits. Circulation Research. 83: 141-6. PMID 9686753 DOI: 10.1161/01.RES.83.2.141 |
0.604 |
|
| 1997 |
Heath B, Xia J, Kass RS. Molecular pharmacology of UK-118, 434-05, a permanently charged amlodipine analog. International Journal of Cardiology. 62: S47-54. PMID 9488195 DOI: 10.1016/S0167-5273(97)00241-6 |
0.464 |
|
| 1997 |
Freeman LC, Pacioretty LM, Moise NS, Kass RS, Gilmour RF. Decreased density of Ito in left ventricular myocytes from German shepherd dogs with inherited arrhythmias. Journal of Cardiovascular Electrophysiology. 8: 872-83. PMID 9261713 DOI: 10.1111/J.1540-8167.1997.Tb00848.X |
0.35 |
|
| 1996 |
Bangalore R, Mehrke G, Gingrich K, Hofmann F, Kass RS. Influence of L-type Ca channel alpha 2/delta-subunit on ionic and gating current in transiently transfected HEK 293 cells. The American Journal of Physiology. 270: H1521-8. PMID 8928856 DOI: 10.1152/Ajpheart.1996.270.5.H1521 |
0.51 |
|
| 1996 |
An RH, Bangalore R, Rosero SZ, Kass RS. Lidocaine block of LQT-3 mutant human Na+ channels. Circulation Research. 79: 103-8. PMID 8925557 DOI: 10.1161/01.Res.79.1.103 |
0.652 |
|
| 1996 |
Kass RS, Davies MP. The roles of ion channels in an inherited heart disease: molecular genetics of the long QT syndrome. Cardiovascular Research. 32: 443-54. PMID 8881507 DOI: 10.1016/0008-6363(96)00122-8 |
0.362 |
|
| 1996 |
Davies MP, Freeman LC, Kass RS. Dual actions of the novel class III antiarrhythmic drug NE-10064 on delayed potassium channel currents in guinea pig ventricular and sinoatrial node cells. The Journal of Pharmacology and Experimental Therapeutics. 276: 1149-54. PMID 8786546 |
0.341 |
|
| 1996 |
Davies MP, An RH, Doevendans P, Kubalak S, Chien KR, Kass RS. Developmental changes in ionic channel activity in the embryonic murine heart. Circulation Research. 78: 15-25. PMID 8603498 DOI: 10.1161/01.Res.78.1.15 |
0.597 |
|
| 1996 |
An RH, Davies MP, Doevendans PA, Kubalak SW, Bangalore R, Chien KR, Kass RS. Developmental changes in beta-adrenergic modulation of L-type Ca2+ channels in embryonic mouse heart. Circulation Research. 78: 371-8. PMID 8593695 DOI: 10.1161/01.Res.78.3.371 |
0.44 |
|
| 1995 |
Gingrich KJ, Roberts WA, Kass RS. Dependence of the GABAA receptor gating kinetics on the alpha-subunit isoform: implications for structure-function relations and synaptic transmission. The Journal of Physiology. 489: 529-43. PMID 8847645 DOI: 10.1113/Jphysiol.1995.Sp021070 |
0.313 |
|
| 1995 |
Kwan YW, Bangalore R, Lakitsh M, Glossmann H, Kass RS. Inhibition of cardiac L-type calcium channels by quaternary amlodipine: implications for pharmacokinetics and access to dihydropyridine binding site. Journal of Molecular and Cellular Cardiology. 27: 253-62. PMID 7760349 DOI: 10.1016/S0022-2828(08)80024-7 |
0.494 |
|
| 1994 |
Bangalore R, Baindur N, Rutledge A, Triggle DJ, Kass RS. L-type calcium channels: asymmetrical intramembrane binding domain revealed by variable length, permanently charged 1,4-dihydropyridines. Molecular Pharmacology. 46: 660-6. PMID 7969044 |
0.332 |
|
| 1994 |
Kwok WM, Kass RS. Inhibition of pinacidil induced IK(ATP) in heart by changes in extracellular pH. Cardiovascular Research. 28: 836-40. PMID 7923288 DOI: 10.1093/Cvr/28.6.836 |
0.614 |
|
| 1994 |
Nelson EJ, Li CC, Bangalore R, Benson T, Kass RS, Hinkle PM. Inhibition of L-type calcium-channel activity by thapsigargin and 2,5-t-butylhydroquinone, but not by cyclopiazonic acid. The Biochemical Journal. 302: 147-54. PMID 7520693 DOI: 10.1042/Bj3020147 |
0.41 |
|
| 1994 |
Kass RS, Bangalore R. Measurement of Dihydropyridine Modulation of Cardiac L-Type Calcium Channels: Molecular and Cellular Implications Methods in Neurosciences. 19: 189-204. DOI: 10.1016/B978-0-12-185287-0.50016-8 |
0.543 |
|
| 1993 |
Kass RS, Freeman LC. Potassium channels in the heart Cellular, molecular, and clinical implications. Trends in Cardiovascular Medicine. 3: 149-59. PMID 21244942 DOI: 10.1016/1050-1738(93)90016-Y |
0.537 |
|
| 1993 |
Welling A, Kwan YW, Bosse E, Flockerzi V, Hofmann F, Kass RS. Subunit-dependent modulation of recombinant L-type calcium channels. Molecular basis for dihydropyridine tissue selectivity. Circulation Research. 73: 974-80. PMID 8403267 DOI: 10.1161/01.Res.73.5.974 |
0.562 |
|
| 1993 |
Freeman LC, Kass RS. Expression of a minimal K+ channel protein in mammalian cells and immunolocalization in guinea pig heart. Circulation Research. 73: 968-73. PMID 8403266 DOI: 10.1161/01.Res.73.5.968 |
0.543 |
|
| 1993 |
Kwok WM, Kass RS. Block of cardiac ATP-sensitive K+ channels by external divalent cations is modulated by intracellular ATP. Evidence for allosteric regulation of the channel protein. The Journal of General Physiology. 102: 693-712. PMID 8270910 DOI: 10.1085/Jgp.102.4.693 |
0.666 |
|
| 1993 |
Freeman LC, Kass RS. Delayed rectifier potassium channels in ventricle and sinoatrial node of the guinea pig: molecular and regulatory properties. Cardiovascular Drugs and Therapy / Sponsored by the International Society of Cardiovascular Pharmacotherapy. 7: 627-35. PMID 8251433 DOI: 10.1007/BF00877630 |
0.539 |
|
| 1993 |
Kwan YW, Kass RS. Interactions between H+ and Ca2+ near cardiac L-type calcium channels: evidence for independent channel-associated binding sites. Biophysical Journal. 65: 1188-95. PMID 8241399 DOI: 10.1016/S0006-3495(93)81152-4 |
0.477 |
|
| 1992 |
Anumonwo JM, Freeman LC, Kwok WM, Kass RS. Delayed rectification in single cells isolated from guinea pig sinoatrial node. The American Journal of Physiology. 262: H921-5. PMID 1558202 |
0.496 |
|
| 1992 |
Freeman LC, Kass RS. Insensitivity of guinea pig ventricular delayed rectifier IK to intracellular trypsin: implications for channel structure and function. Cardiovascular Research. 26: 1131-6. PMID 1337868 DOI: 10.1093/cvrese/26.11.1131 |
0.559 |
|
| 1992 |
Haymes AA, Kwan YW, Arena JP, Kass RS, Hinkle PM. Activation of protein kinase C reduces L-type calcium channel activity of GH3 pituitary cells. The American Journal of Physiology. 262: C1211-9. PMID 1317102 DOI: 10.1152/Ajpcell.1992.262.5.C1211 |
0.461 |
|
| 1992 |
Freeman LC, Kwok WM, Kass RS. Phosphorylation-independent regulation of cardiac IK by guanine nucleotides and isoproterenol. The American Journal of Physiology. 262: H1298-302. PMID 1314511 DOI: 10.1152/Ajpheart.1992.262.4.H1298 |
0.645 |
|
| 1991 |
Walsh KB, Arena JP, Kwok WM, Freeman L, Kass RS. Delayed-rectifier potassium channel activity in isolated membrane patches of guinea pig ventricular myocytes. The American Journal of Physiology. 260: H1390-3. PMID 1849375 DOI: 10.1152/Ajpheart.1991.260.4.H1390 |
0.693 |
|
| 1991 |
Walsh KB, Kass RS. Distinct voltage-dependent regulation of a heart-delayed IK by protein kinases A and C. The American Journal of Physiology. 261: C1081-90. PMID 1662903 DOI: 10.1152/Ajpcell.1991.261.6.C1081 |
0.339 |
|
| 1991 |
Kass RS, Arena JP, Chin S. Block of L-type calcium channels by charged dihydropyridines. Sensitivity to side of application and calcium. The Journal of General Physiology. 98: 63-75. PMID 1658191 |
0.325 |
|
| 1991 |
Anumonwo JMB, Freeman LC, Kwok WM, Kass RS. Potassium channels in the heart: Electrophysiology and pharmacological regulation Cardiovascular Drug Reviews. 9: 299-316. |
0.678 |
|
| 1990 |
Arena JP, Walsh KB, Kass RS. Measurement, block, and modulation of potassium channel currents in the heart. Progress in Clinical and Biological Research. 334: 43-63. PMID 2309009 |
0.477 |
|
| 1990 |
Kass RS, Arena JP, Walsh KB. Measurement and block of potassium channel currents in the heart: Importance of channel type Drug Development Research. 19: 115-127. DOI: 10.1002/Ddr.430190203 |
0.553 |
|
| 1989 |
Arena JP, Kass RS. Enhancement of potassium-sensitive current in heart cells by pinacidil. Evidence for modulation of the ATP-sensitive potassium channel. Circulation Research. 65: 436-45. PMID 2752550 |
0.51 |
|
| 1989 |
Bennett PB, Kass R, Begenisich T. Nonstationary fluctuation analysis of the delayed rectifier K channel in cardiac Purkinje fibers. Actions of norepinephrine on single-channel current. Biophysical Journal. 55: 731-738. PMID 2720070 DOI: 10.1016/S0006-3495(89)82872-3 |
0.576 |
|
| 1989 |
Kass RS, Arena JP, Chin S. Cellular electrophysiology of amlodipine: probing the cardiac L-type calcium channel. The American Journal of Cardiology. 64: 35I-41I; discussion . PMID 2554712 DOI: 10.1016/0002-9149(89)90958-2 |
0.368 |
|
| 1989 |
Kass RS, Arena JP. Influence of pHo on calcium channel block by amlodipine, a charged dihydropyridine compound. Implications for location of the dihydropyridine receptor. The Journal of General Physiology. 93: 1109-27. PMID 2549176 |
0.399 |
|
| 1989 |
Kass RS, Arena JP, Chin S. Modulation of calcium channels by charged and neutral dihydropyridines. Annals of the New York Academy of Sciences. 560: 189-97. PMID 2545132 |
0.333 |
|
| 1989 |
Arena JP, Kass RS. Activation of ATP-sensitive K channels in heart cells by pinacidil: dependence on ATP. The American Journal of Physiology. 257: H2092-6. PMID 2513734 DOI: 10.1152/Ajpheart.1989.257.6.H2092 |
0.545 |
|
| 1989 |
Walsh KB, Begenisich TB, Kass RS. Beta-adrenergic modulation of cardiac ion channels. Differential temperature sensitivity of potassium and calcium currents. The Journal of General Physiology. 93: 841-54. PMID 2472462 |
0.418 |
|
| 1988 |
Walsh KB, Kass RS. Regulation of a heart potassium channel by protein kinase A and C. Science (New York, N.Y.). 242: 67-9. PMID 2845575 DOI: 10.1126/Science.2845575 |
0.417 |
|
| 1988 |
Kass RS, Arena JP, DiManno D. Block of heart calcium channels by amlodipine: influence of drug charge on blocking activity. Journal of Cardiovascular Pharmacology. 12: S45-9. PMID 2467128 DOI: 10.1097/00005344-198812007-00010 |
0.55 |
|
| 1988 |
Krafte DS, Kass RS. Hydrogen ion modulation of Ca channel current in cardiac ventricular cells. Evidence for multiple mechanisms. The Journal of General Physiology. 91: 641-57. PMID 2458428 DOI: 10.1085/Jgp.91.5.641 |
0.488 |
|
| 1988 |
Arena JP, Kass RS. Block of heart potassium channels by clofilium and its tertiary analogs: relationship between drug structure and type of channel blocked. Molecular Pharmacology. 34: 60-6. PMID 2455861 |
0.46 |
|
| 1988 |
Walsh KB, Begenisich TB, Kass RS. Beta-adrenergic modulation in the heart. Independent regulation of K and Ca channels. PflüGers Archiv : European Journal of Physiology. 411: 232-4. PMID 2451808 DOI: 10.1007/BF00582323 |
0.361 |
|
| 1987 |
Kass RS. Voltage-dependent modulation of cardiac calcium channel current by optical isomers of Bay K 8644: implications for channel gating. Circulation Research. 61: I1-5. PMID 2443269 |
0.451 |
|
| 1987 |
Arena JP, Kass RS. NEW PHARMACOLOGICAL PROBES FOR THE STUDY OF HEART K CHANNELS Ieee/Engineering in Medicine and Biology Society Annual Conference. 132-133. |
0.459 |
|
| 1986 |
Sanguinetti MC, Krafte DS, Kass RS. Voltage-dependent modulation of Ca channel current in heart cells by Bay K8644. The Journal of General Physiology. 88: 369-92. PMID 2428922 DOI: 10.1085/Jgp.88.3.369 |
0.52 |
|
| 1986 |
Bennett P, McKinney L, Begenisich T, Kass RS. Adrenergic modulation of the delayed rectifier potassium channel in calf cardiac Purkinje fibers. Biophysical Journal. 49: 839-48. PMID 2424513 DOI: 10.1016/S0006-3495(86)83713-4 |
0.602 |
|
| 1985 |
Bennett PB, McKinney LC, Kass RS, Begenisich T. Delayed rectification in the calf cardiac Purkinje fiber. Evidence for multiple state kinetics. Biophysical Journal. 48: 553-67. PMID 2413917 DOI: 10.1016/S0006-3495(85)83813-3 |
0.541 |
|
| 1984 |
Sanguinetti MC, Kass RS. Photoalteration of calcium channel blockade in the cardiac Purkinje fiber. Biophysical Journal. 45: 873-80. PMID 6329345 DOI: 10.1016/S0006-3495(84)84233-2 |
0.514 |
|
| 1984 |
Sanguinetti MC, Kass RS. Regulation of cardiac calcium channel current and contractile activity by the dihydropyridine Bay K 8644 is voltage-dependent. Journal of Molecular and Cellular Cardiology. 16: 667-70. PMID 6206231 DOI: 10.1016/S0022-2828(84)80631-8 |
0.57 |
|
| 1984 |
Kass RS, Sanguinetti MC. Inactivation of calcium channel current in the calf cardiac Purkinje fiber. Evidence for voltage- and calcium-mediated mechanisms. The Journal of General Physiology. 84: 705-26. PMID 6096480 DOI: 10.1085/Jgp.84.5.705 |
0.434 |
|
| 1984 |
Sanguinetti MC, Kass RS. Voltage-dependent block of calcium channel current in the calf cardiac Purkinje fiber by dihydropyridine calcium channel antagonists. Circulation Research. 55: 336-48. PMID 6088117 DOI: 10.1161/01.Res.55.3.336 |
0.542 |
|
| 1982 |
Kass RS, Tsien RW. Fluctuations in membrane current driven by intracellular calcium in cardiac Purkinje fibers. Biophysical Journal. 38: 259-69. PMID 6809065 DOI: 10.1016/S0006-3495(82)84557-8 |
0.585 |
|
| 1982 |
Kass RS, Scheuer T. Slow inactivation of calcium channels in the cardiac Purkinje fiber. Journal of Molecular and Cellular Cardiology. 14: 615-8. PMID 6296410 DOI: 10.1016/0022-2828(82)90148-1 |
0.57 |
|
| 1982 |
Kass RS, Scheuer T, Malloy KJ. Block of outward current in cardiac Purkinje fibers by injection of quaternary ammonium ions. The Journal of General Physiology. 79: 1041-63. PMID 6286842 DOI: 10.1085/Jgp.79.6.1041 |
0.498 |
|
| 1981 |
Kass RS, Blair ML. Effects of angiotensin II on membrane current in cardiac Purkinje fibers. Journal of Molecular and Cellular Cardiology. 13: 797-809. PMID 7299830 DOI: 10.1016/0022-2828(81)90237-6 |
0.349 |
|
| 1979 |
Tsien RW, Kass RS, Weingart R. Cellular and subcellular mechanisms of cardiac pacemaker oscillations. The Journal of Experimental Biology. 81: 205-15. PMID 512578 |
0.504 |
|
| 1979 |
Kass RS, Siegelbaum SA, Tsien RW. Three-micro-electrode voltage clamp experiments in calf cardiac Purkinje fibres: is slow inward current adequately measured? The Journal of Physiology. 290: 201-25. PMID 469751 DOI: 10.1113/jphysiol.1979.sp012768 |
0.701 |
|
| 1978 |
Kass RS, Tsien RW, Weingart R. Ionic basis of transient inward current induced by strophanthidin in cardiac Purkinje fibres. The Journal of Physiology. 281: 209-26. PMID 702372 DOI: 10.1113/jphysiol.1978.sp012417 |
0.645 |
|
| 1978 |
Kass RS, Lederer WJ, Tsien RW, Weingart R. Role of calcium ions in transient inward currents and aftercontractions induced by strophanthidin in cardiac Purkinje fibres. The Journal of Physiology. 281: 187-208. PMID 702368 DOI: 10.1113/jphysiol.1978.sp012416 |
0.68 |
|
| 1978 |
Weingart R, Kass RS, Tsien RW. Is digitalis inotropy associated with enhanced slow inward calcium current? Nature. 273: 389-92. PMID 661951 DOI: 10.1038/273389a0 |
0.476 |
|
| 1978 |
Tsien RW, Kass RS, Weingart R. Calcium ions and membrane current changes induced by digitals in cardiac Purkinje fibers. Annals of the New York Academy of Sciences. 307: 483-90. PMID 360946 DOI: 10.1111/J.1749-6632.1978.Tb41978.X |
0.479 |
|
| 1977 |
Siegelbaum SA, Tsien RW, Kass RS. Role of intracellular calcium in the transient outward current of calf Purkinje fibres. Nature. 269: 611-3. PMID 917108 DOI: 10.1038/269611a0 |
0.656 |
|
| 1977 |
Kass RS, Tsien RW, Weingart R. Strophanthidin can increase the slow inward current and alter its repriming kinetics Biophysical Journal. 17: 4a. |
0.498 |
|
| 1977 |
Weingart R, Kass RS, Tsien RW. Roles of calcium and sodium ions in the transient inward current induced by strophanthidin in cardiac Purkinje fibers Biophysical Journal. 17: 3a. |
0.5 |
|
| 1976 |
Kass RS, Tsien RW. Control of action potential duration by calcium ions in cardiac Purkinje fibers. The Journal of General Physiology. 67: 599-617. PMID 1271045 DOI: 10.1085/Jgp.67.5.599 |
0.58 |
|
| 1976 |
Kass RS, Siegelbaum S, Tsien RW. Incomplete inactivation of the slow inward current in cardiac Purkinje fibres [proceedings]. The Journal of Physiology. 263: 127P-128P. PMID 1011098 |
0.551 |
|
| 1976 |
Kass RS, Kederer WJ, Tsien RW. Current fluctuations in strophanthidin treated cardiac Purkinje fibers Biophysical Journal. 16. |
0.473 |
|
| 1975 |
Kass RS, Tsien RW. Multiple effects of calcium antagonists on plateau currents in cardiac Purkinje fibers. The Journal of General Physiology. 66: 169-92. PMID 1176946 DOI: 10.1085/Jgp.66.2.169 |
0.537 |
|
| 1975 |
Kass RS, Tsien RW. Analysis of the three microelectrode method as applied to inward currents in cardiac Purkinje fibers Biophysical Journal. 15. |
0.479 |
|
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