Carlos G. Dotti - Publications

Katholieke Universiteit Leuven, Leuven, Vlaanderen, Belgium 

144 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Martín-Segura A, Ahmed T, Casadomé-Perales Á, Palomares-Perez I, Palomer E, Kerstens A, Munck S, Balschun D, Dotti CG. Age-associated cholesterol reduction triggers brain insulin resistance by facilitating ligand-independent receptor activation and pathway desensitization. Aging Cell. e12932. PMID 30884121 DOI: 10.1111/acel.12932  0.32
2016 Knafo S, Sánchez-Puelles C, Palomer E, Delgado I, Draffin JE, Mingo J, Wahle T, Kaleka K, Mou L, Pereda-Perez I, Klosi E, Faber EB, Chapman HM, Lozano-Montes L, Ortega-Molina A, ... ... Dotti CG, et al. PTEN recruitment controls synaptic and cognitive function in Alzheimer's models. Nature Neuroscience. PMID 26780512 DOI: 10.1038/nn.4225  1
2015 Pasciuto E, Ahmed T, Wahle T, Gardoni F, D'Andrea L, Pacini L, Jacquemont S, Tassone F, Balschun D, Dotti CG, Callaerts-Vegh Z, D'Hooge R, Müller UC, Di Luca M, De Strooper B, et al. Dysregulated ADAM10-Mediated Processing of APP during a Critical Time Window Leads to Synaptic Deficits in Fragile X Syndrome. Neuron. 87: 382-98. PMID 26182420 DOI: 10.1016/j.neuron.2015.06.032  1
2015 Brachet A, Norwood S, Brouwers JF, Palomer E, Helms JB, Dotti CG, Esteban JA. LTP-triggered cholesterol redistribution activates Cdc42 and drives AMPA receptor synaptic delivery. The Journal of Cell Biology. 208: 791-806. PMID 25753037 DOI: 10.1083/jcb.201407122  1
2015 Schulz JG, Laranjeira A, Van Huffel L, Gärtner A, Vilain S, Bastianen J, Van Veldhoven PP, Dotti CG. Glial β-oxidation regulates Drosophila energy metabolism. Scientific Reports. 5: 7805. PMID 25588812 DOI: 10.1038/srep07805  1
2015 Gärtner A, Fornasiero EF, Dotti CG. Cadherins as regulators of neuronal polarity. Cell Adhesion & Migration. 9: 175-82. PMID 25482615 DOI: 10.4161/19336918.2014.983808  1
2015 Trovò L, Stroobants S, D'Hooge R, Ledesma MD, Dotti CG. Improvement of biochemical and behavioral defects in the Niemann-Pick type A mouse by intraventricular infusion of MARCKS. Neurobiology of Disease. 73: 319-26. PMID 25251606 DOI: 10.1016/j.nbd.2014.09.008  1
2015 Pasciuto E, Ahmed T, Wahle T, Gardoni F, D'Andrea L, Pacini L, Jacquemont S, Tassone F, Balschun D, Dotti CG, Callaerts-Vegh Z, D'Hooge R, Müller UC, Di Luca M, De Strooper B, et al. Errata to Dysregulated ADAM10-Mediated Processing of APP during a Critical Time Window Leads to SynapticDeficits in Fragile X Syndrome [Neuron, 87, (2015), 382-398] Neuron. 87: 908. DOI: 10.1016/j.neuron.2015.08.010  1
2014 La Fata G, Gärtner A, Domínguez-Iturza N, Dresselaers T, Dawitz J, Poorthuis RB, Averna M, Himmelreich U, Meredith RM, Achsel T, Dotti CG, Bagni C. FMRP regulates multipolar to bipolar transition affecting neuronal migration and cortical circuitry. Nature Neuroscience. 17: 1693-700. PMID 25402856 DOI: 10.1038/nn.3870  1
2014 Martín MG, Pfrieger F, Dotti CG. Cholesterol in brain disease: sometimes determinant and frequently implicated. Embo Reports. 15: 1036-52. PMID 25223281 DOI: 10.15252/embr.201439225  1
2014 Dotti CG, Esteban JA, Ledesma MD. Lipid dynamics at dendritic spines. Frontiers in Neuroanatomy. 8: 76. PMID 25152717 DOI: 10.3389/fnana.2014.00076  1
2014 Gärtner A, Fornasiero EF, Valtorta F, Dotti CG. Distinct temporal hierarchies in membrane and cytoskeleton dynamics precede the morphological polarization of developing neurons. Journal of Cell Science. 127: 4409-19. PMID 25128563 DOI: 10.1242/jcs.149815  1
2014 Martin MG, Ahmed T, Korovaichuk A, Venero C, Menchón SA, Salas I, Munck S, Herreras O, Balschun D, Dotti CG. Constitutive hippocampal cholesterol loss underlies poor cognition in old rodents. Embo Molecular Medicine. 6: 902-17. PMID 24878762 DOI: 10.15252/emmm.201303711  1
2014 Berto GE, Iobbi C, Camera P, Scarpa E, Iampietro C, Bianchi F, Gai M, Sgrò F, Cristofani F, Gärtner A, Dotti CG, Di Cunto F. The DCR protein TTC3 affects differentiation and Golgi compactness in neurons through specific actin-regulating pathways. Plos One. 9: e93721. PMID 24695496 DOI: 10.1371/journal.pone.0093721  1
2014 Kappagantula S, Andrews MR, Cheah M, Abad-Rodriguez J, Dotti CG, Fawcett JW. Neu3 sialidase-mediated ganglioside conversion is necessary for axon regeneration and is blocked in CNS axons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2477-92. PMID 24523539 DOI: 10.1523/JNEUROSCI.4432-13.2014  1
2014 Gabandé-Rodríguez E, Boya P, Labrador V, Dotti CG, Ledesma MD. High sphingomyelin levels induce lysosomal damage and autophagy dysfunction in Niemann Pick disease type A. Cell Death and Differentiation. 21: 864-75. PMID 24488099 DOI: 10.1038/cdd.2014.4  1
2014 Dotti CG, De Anda FC, Gärtner A. Control of Axon and Dendrite Identity and Structure Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.04510-4  1
2013 Agostini F, Dotti CG, Pérez-Cañamás A, Ledesma MD, Benetti F, Legname G. Prion protein accumulation in lipid rafts of mouse aging brain. Plos One. 8: e74244. PMID 24040215 DOI: 10.1371/journal.pone.0074244  1
2013 Iannilli F, Zalfa F, Gartner A, Bagni C, Dotti CG. Cytoplasmic TERT Associates to RNA Granules in Fully Mature Neurons: Role in the Translational Control of the Cell Cycle Inhibitor p15INK4B. Plos One. 8: e66602. PMID 23825548 DOI: 10.1371/journal.pone.0066602  1
2013 Micholt L, Gärtner A, Prodanov D, Braeken D, Dotti CG, Bartic C. Substrate topography determines neuronal polarization and growth in vitro. Plos One. 8: e66170. PMID 23785482 DOI: 10.1371/journal.pone.0066170  1
2013 Trovò L, Ahmed T, Callaerts-Vegh Z, Buzzi A, Bagni C, Chuah M, Vandendriessche T, D'Hooge R, Balschun D, Dotti CG. Low hippocampal PI(4,5)Pâ‚‚ contributes to reduced cognition in old mice as a result of loss of MARCKS. Nature Neuroscience. 16: 449-55. PMID 23434911 DOI: 10.1038/nn.3342  1
2013 Shariati SA, Lau P, Hassan BA, Müller U, Dotti CG, De Strooper B, Gärtner A. APLP2 regulates neuronal stem cell differentiation during cortical development. Journal of Cell Science. 126: 1268-77. PMID 23345401 DOI: 10.1242/jcs.122440  1
2012 Cáceres A, Ye B, Dotti CG. Neuronal polarity: demarcation, growth and commitment. Current Opinion in Cell Biology. 24: 547-53. PMID 22726583 DOI: 10.1016/  1
2012 Gärtner A, Fornasiero EF, Dotti CG. N-cadherin: a new player in neuronal polarity. Cell Cycle (Georgetown, Tex.). 11: 2223-4. PMID 22659798 DOI: 10.4161/cc.20797  1
2012 Totaro A, Tavano S, Filosa G, Gärtner A, Pennucci R, Santambrogio P, Bachi A, Dotti CG, de Curtis I. Biochemical and functional characterisation of αPIX, a specific regulator of axonal and dendritic branching in hippocampal neurons. Biology of the Cell / Under the Auspices of the European Cell Biology Organization. 104: 533-52. PMID 22554054 DOI: 10.1111/boc.201100060  1
2012 Guix FX, Wahle T, Vennekens K, Snellinx A, Chávez-Gutiérrez L, Ill-Raga G, Ramos-Fernandez E, Guardia-Laguarta C, Lleó A, Arimon M, Berezovska O, Muñoz FJ, Dotti CG, De Strooper B. Modification of γ-secretase by nitrosative stress links neuronal ageing to sporadic Alzheimer's disease. Embo Molecular Medicine. 4: 660-73. PMID 22488900 DOI: 10.1002/emmm.201200243  1
2012 Gärtner A, Fornasiero EF, Munck S, Vennekens K, Seuntjens E, Huttner WB, Valtorta F, Dotti CG. N-cadherin specifies first asymmetry in developing neurons. The Embo Journal. 31: 1893-903. PMID 22354041 DOI: 10.1038/emboj.2012.41  1
2012 Menchón SA, Martín MG, Dotti CG. APM_GUI: analyzing particle movement on the cell membrane and determining confinement. Bmc Biophysics. 5: 4. PMID 22348508 DOI: 10.1186/2046-1682-5-4  1
2012 Sodero AO, Vriens J, Ghosh D, Stegner D, Brachet A, Pallotto M, Sassoè-Pognetto M, Brouwers JF, Helms JB, Nieswandt B, Voets T, Dotti CG. Cholesterol loss during glutamate-mediated excitotoxicity. The Embo Journal. 31: 1764-73. PMID 22343944 DOI: 10.1038/emboj.2012.31  1
2012 Ledesma MD, Dotti CG. Peripheral cholesterol, metabolic disorders and Alzheimer's disease. Frontiers in Bioscience (Elite Edition). 4: 181-94. PMID 22201863  1
2012 Ledesma MD, Martin MG, Dotti CG. Lipid changes in the aged brain: effect on synaptic function and neuronal survival. Progress in Lipid Research. 51: 23-35. PMID 22142854 DOI: 10.1016/j.plipres.2011.11.004  1
2012 Michaki V, Guix FX, Vennekens K, Munck S, Dingwall C, Davis JB, Townsend DM, Tew KD, Feiguin F, De Strooper B, Dotti CG, Wahle T. Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-β production by altering Nicastrin maturation and intracellular localization. The Journal of Biological Chemistry. 287: 1100-11. PMID 22086926 DOI: 10.1074/jbc.M111.288258  1
2012 Nesic I, Guix FX, Vennekens K, Michaki V, Van Veldhoven PP, Feiguin F, De Strooper B, Dotti CG, Wahle T. Alterations in phosphatidylethanolamine levels affect the generation of Aβ. Aging Cell. 11: 63-72. PMID 22023223 DOI: 10.1111/j.1474-9726.2011.00760.x  1
2011 Pollarolo G, Schulz JG, Munck S, Dotti CG. Cytokinesis remnants define first neuronal asymmetry in vivo. Nature Neuroscience. 14: 1525-33. PMID 22081156 DOI: 10.1038/nn.2976  1
2011 Menchón SA, Gärtner A, Román P, Dotti CG. Neuronal (bi)polarity as a self-organized process enhanced by growing membrane. Plos One. 6: e24190. PMID 21935383 DOI: 10.1371/journal.pone.0024190  1
2011 Bianchi FT, Camera P, Ala U, Imperiale D, Migheli A, Boda E, Tempia F, Berto G, Bosio Y, Oddo S, LaFerla FM, Taraglio S, Dotti CG, Di Cunto F. The collagen chaperone HSP47 is a new interactor of APP that affects the levels of extracellular beta-amyloid peptides. Plos One. 6: e22370. PMID 21829458 DOI: 10.1371/journal.pone.0022370  1
2011 Trovò L, Van Veldhoven PP, Martín MG, Dotti CG. Sphingomyelin upregulation in mature neurons contributes to TrkB activity by Rac1 endocytosis. Journal of Cell Science. 124: 1308-15. PMID 21444756 DOI: 10.1242/jcs.078766  1
2011 Sodero AO, Trovò L, Iannilli F, Van Veldhoven P, Dotti CG, Martin MG. Regulation of tyrosine kinase B activity by the Cyp46/cholesterol loss pathway in mature hippocampal neurons: relevance for neuronal survival under stress and in aging. Journal of Neurochemistry. 116: 747-55. PMID 21214568 DOI: 10.1111/j.1471-4159.2010.07079.x  1
2011 Sodero AO, Weissmann C, Ledesma MD, Dotti CG. Cellular stress from excitatory neurotransmission contributes to cholesterol loss in hippocampal neurons aging in vitro. Neurobiology of Aging. 32: 1043-53. PMID 20663588 DOI: 10.1016/j.neurobiolaging.2010.06.001  1
2011 Iannilli F, Sodero AO, Ledesma MD, Dotti CG. Oxidative stress activates the pro-survival TrkA pathway through membrane cholesterol loss. Neurobiology of Aging. 32: 1033-42. PMID 19679377 DOI: 10.1016/j.neurobiolaging.2009.07.006  1
2011 Martin MG, Trovò L, Perga S, Sadowska A, Rasola A, Chiara F, Dotti CG. Cyp46-mediated cholesterol loss promotes survival in stressed hippocampal neurons. Neurobiology of Aging. 32: 933-43. PMID 19497639 DOI: 10.1016/j.neurobiolaging.2009.04.022  1
2011 Bergmans BA, Dotti CG, De Strooper B. Neuronal differentiation of murine embryonic stem cells Human Mesenchymal and Embryonic Stem Cells. 175-190.  1
2010 Martin M, Dotti CG, Ledesma MD. Brain cholesterol in normal and pathological aging. Biochimica Et Biophysica Acta. 1801: 934-44. PMID 20359547 DOI: 10.1016/j.bbalip.2010.03.011  1
2010 Bergmans BA, Shariati SA, Habets RL, Verstreken P, Schoonjans L, Müller U, Dotti CG, De Strooper B. Neurons generated from APP/APLP1/APLP2 triple knockout embryonic stem cells behave normally in vitro and in vivo: lack of evidence for a cell autonomous role of the amyloid precursor protein in neuronal differentiation. Stem Cells (Dayton, Ohio). 28: 399-406. PMID 20049903 DOI: 10.1002/stem.296  1
2010 Maritzen T, Schmidt MR, Kukhtina V, Higman VA, Strauss H, Volkmer R, Oschkinat H, Dotti CG, Haucke V. A novel subtype of AP-1-binding motif within the palmitoylated trans-Golgi network/endosomal accessory protein Gadkin/gamma-BAR. The Journal of Biological Chemistry. 285: 4074-86. PMID 19965873 DOI: 10.1074/jbc.M109.049197  1
2010 Higuero AM, Sánchez-Ruiloba L, Doglio LE, Portillo F, Abad-Rodríguez J, Dotti CG, Iglesias T. Kidins220/ARMS modulates the activity of microtubule-regulating proteins and controls neuronal polarity and development. The Journal of Biological Chemistry. 285: 1343-57. PMID 19903810 DOI: 10.1074/jbc.M109.024703  1
2010 Dotti CG, Gärtner A, Calderon de Anda F. Axonal and Dendritic Identity and Structure: Control of Encyclopedia of Neuroscience. 1093-1100. DOI: 10.1016/B978-008045046-9.00717-8  1
2009 Schmidt MR, Maritzen T, Kukhtina V, Higman VA, Doglio L, Barak NN, Strauss H, Oschkinat H, Dotti CG, Haucke V. Regulation of endosomal membrane traffic by a Gadkin/AP-1/kinesin KIF5 complex. Proceedings of the National Academy of Sciences of the United States of America. 106: 15344-9. PMID 19706427 DOI: 10.1073/pnas.0904268106  1
2009 Gärtner A, Dotti CG. Neuronal polarity: consolidation for growth, growth for consolidation. The Embo Journal. 28: 173-4. PMID 19194485 DOI: 10.1038/emboj.2008.296  1
2009 Dotti CG, De Strooper B. Alzheimer's dementia by circulation disorders: when trees hide the forest. Nature Cell Biology. 11: 114-6. PMID 19188916 DOI: 10.1038/ncb0209-114  1
2009 Meloni I, Parri V, De Filippis R, Ariani F, Artuso R, Bruttini M, Katzaki E, Longo I, Mari F, Bellan C, Dotti CG, Renieri A. The XLMR gene ACSL4 plays a role in dendritic spine architecture. Neuroscience. 159: 657-69. PMID 19166906 DOI: 10.1016/j.neuroscience.2008.11.056  1
2008 Camera P, Schubert V, Pellegrino M, Berto G, Vercelli A, Muzzi P, Hirsch E, Altruda F, Dotti CG, Di Cunto F. The RhoA-associated protein Citron-N controls dendritic spine maintenance by interacting with spine-associated Golgi compartments. Embo Reports. 9: 384-92. PMID 18309323 DOI: 10.1038/embor.2008.21  1
2008 Martin MG, Perga S, Trovò L, Rasola A, Holm P, Rantamäki T, Harkany T, Castrén E, Chiara F, Dotti CG. Cholesterol loss enhances TrkB signaling in hippocampal neurons aging in vitro. Molecular Biology of the Cell. 19: 2101-12. PMID 18287532 DOI: 10.1091/mbc.E07-09-0897  1
2008 Calderon de Anda F, Gärtner A, Tsai LH, Dotti CG. Pyramidal neuron polarity axis is defined at the bipolar stage. Journal of Cell Science. 121: 178-85. PMID 18187450 DOI: 10.1242/jcs.023143  1
2008 Pastor MT, Kümmerer N, Schubert V, Esteras-Chopo A, Dotti CG, López de la Paz M, Serrano L. Amyloid toxicity is independent of polypeptide sequence, length and chirality. Journal of Molecular Biology. 375: 695-707. PMID 18036611 DOI: 10.1016/j.jmb.2007.08.012  1
2007 Dotti CG, Feiguin F, Fortini ME. gamma-cleavage-independent functions of presenilin, nicastrin, and Aph-1 regulate cell-junction organization and prevent tau toxicity in vivo. Neuron. 53: 463. PMID 17326324 DOI: 10.1016/j.neuron.2007.01.012  1
2007 Schubert V, Dotti CG. Transmitting on actin: synaptic control of dendritic architecture. Journal of Cell Science. 120: 205-12. PMID 17215449 DOI: 10.1242/jcs.03337  1
2006 Ledesma MD, Dotti CG. Amyloid excess in Alzheimer's disease: what is cholesterol to be blamed for? Febs Letters. 580: 5525-32. PMID 16814780 DOI: 10.1016/j.febslet.2006.06.038  1
2006 Doglio LE, Kanwar R, Jackson GR, Perez M, Avila J, Dingwall C, Dotti CG, Fortini ME, Feiguin F. gamma-cleavage-independent functions of presenilin, nicastrin, and Aph-1 regulate cell-junction organization and prevent tau toxicity in vivo. Neuron. 50: 359-75. PMID 16675392 DOI: 10.1016/j.neuron.2006.03.038  1
2006 Orioli D, Colaluca IN, Stefanini M, Riva S, Dotti CG, Peverali FA. Rac3-induced neuritogenesis requires binding to Neurabin I. Molecular Biology of the Cell. 17: 2391-400. PMID 16525025 DOI: 10.1091/mbc.E05-08-0753  1
2006 Schubert V, Da Silva JS, Dotti CG. Localized recruitment and activation of RhoA underlies dendritic spine morphology in a glutamate receptor-dependent manner. The Journal of Cell Biology. 172: 453-67. PMID 16449195 DOI: 10.1083/jcb.200506136  1
2006 Crameri A, Biondi E, Kuehnle K, Lütjohann D, Thelen KM, Perga S, Dotti CG, Nitsch RM, Ledesma MD, Mohajeri MH. The role of seladin-1/DHCR24 in cholesterol biosynthesis, APP processing and Abeta generation in vivo. The Embo Journal. 25: 432-43. PMID 16407971 DOI: 10.1038/sj.emboj.7600938  1
2005 Galvan C, Camoletto PG, Dotti CG, Aguzzi A, Ledesma MD. Proper axonal distribution of PrP(C) depends on cholesterol-sphingomyelin-enriched membrane domains and is developmentally regulated in hippocampal neurons. Molecular and Cellular Neurosciences. 30: 304-15. PMID 16139509 DOI: 10.1016/j.mcn.2005.07.003  1
2005 de Anda FC, Pollarolo G, Da Silva JS, Camoletto PG, Feiguin F, Dotti CG. Centrosome localization determines neuronal polarity. Nature. 436: 704-8. PMID 16079847 DOI: 10.1038/nature03811  1
2005 Medina MG, Ledesma MD, Domínguez JE, Medina M, Zafra D, Alameda F, Dotti CG, Navarro P. Tissue plasminogen activator mediates amyloid-induced neurotoxicity via Erk1/2 activation. The Embo Journal. 24: 1706-16. PMID 15861134 DOI: 10.1038/sj.emboj.7600650  1
2005 Da Silva JS, Hasegawa T, Miyagi T, Dotti CG, Abad-Rodriguez J. Asymmetric membrane ganglioside sialidase activity specifies axonal fate. Nature Neuroscience. 8: 606-15. PMID 15834419 DOI: 10.1038/nn1442  1
2005 Neubrand VE, Will RD, Möbius W, Poustka A, Wiemann S, Schu P, Dotti CG, Pepperkok R, Simpson JC. Gamma-BAR, a novel AP-1-interacting protein involved in post-Golgi trafficking. The Embo Journal. 24: 1122-33. PMID 15775984 DOI: 10.1038/sj.emboj.7600600  1
2005 Ledesma MD, Dotti CG. The conflicting role of brain cholesterol in Alzheimer's disease: lessons from the brain plasminogen system. Biochemical Society Symposium. 129-38. PMID 15649137  1
2004 Dotti CG, Galvan C, Ledesma MD. Plasmin deficiency in Alzheimer's disease brains: causal or casual? Neuro-Degenerative Diseases. 1: 205-12. PMID 16908991 DOI: 10.1159/000080987  1
2004 Abad-Rodriguez J, Ledesma MD, Craessaerts K, Perga S, Medina M, Delacourte A, Dingwall C, De Strooper B, Dotti CG. Neuronal membrane cholesterol loss enhances amyloid peptide generation. The Journal of Cell Biology. 167: 953-60. PMID 15583033 DOI: 10.1083/jcb.200404149  1
2004 Kopitz J, Russwurm R, Kaltner H, André S, Dotti CG, Gabius HJ, Abad-Rodríguez J. Hippocampal neurons and recombinant galectins as tools for systematic carbohydrate structure-function studies in neuronal differentiation. Brain Research. Developmental Brain Research. 153: 189-96. PMID 15527886 DOI: 10.1016/j.devbrainres.2004.08.005  1
2004 Santos Da Silva J, Schubert V, Dotti CG. RhoA, Rac1, and cdc42 intracellular distribution shift during hippocampal neuron development. Molecular and Cellular Neurosciences. 27: 1-7. PMID 15345238 DOI: 10.1016/j.mcn.2004.03.008  1
2003 Ledesma MD, Abad-Rodriguez J, Galvan C, Biondi E, Navarro P, Delacourte A, Dingwall C, Dotti CG. Raft disorganization leads to reduced plasmin activity in Alzheimer's disease brains. Embo Reports. 4: 1190-6. PMID 14618158 DOI: 10.1038/sj.embor.7400021  1
2003 Camera P, da Silva JS, Griffiths G, Giuffrida MG, Ferrara L, Schubert V, Imarisio S, Silengo L, Dotti CG, Di Cunto F. Citron-N is a neuronal Rho-associated protein involved in Golgi organization through actin cytoskeleton regulation. Nature Cell Biology. 5: 1071-8. PMID 14595335 DOI: 10.1038/ncb1064  1
2003 Ledesma MD, Dotti CG. Membrane and cytoskeleton dynamics during axonal elongation and stabilization. International Review of Cytology. 227: 183-219. PMID 14518552 DOI: 10.1016/S0074-7696(03)01010-6  1
2003 Da Silva JS, Medina M, Zuliani C, Di Nardo A, Witke W, Dotti CG. RhoA/ROCK regulation of neuritogenesis via profilin IIa-mediated control of actin stability. The Journal of Cell Biology. 162: 1267-79. PMID 14517206 DOI: 10.1083/jcb.200304021  1
2003 Ledesma MD, Da Silva JS, Schevchenko A, Wilm M, Dotti CG. Proteomic characterisation of neuronal sphingolipid-cholesterol microdomains: role in plasminogen activation. Brain Research. 987: 107-16. PMID 14499952 DOI: 10.1016/S0006-8993(03)03296-7  1
2003 Medina M, Dotti CG. RIPped out by presenilin-dependent gamma-secretase. Cellular Signalling. 15: 829-41. PMID 12834808 DOI: 10.1016/S0898-6568(03)00041-X  1
2003 Dotti CG, Poo MM. Neuronal polarization: building fences for molecular segregation. Nature Cell Biology. 5: 591-4. PMID 12833059 DOI: 10.1038/ncb0703-591b  1
2002 Ledesma MD, Galvan C, Hellias B, Dotti C, Jensen PH. Astrocytic but not neuronal increased expression and redistribution of parkin during unfolded protein stress Journal of Neurochemistry. 83: 1431-1440. PMID 12472897 DOI: 10.1046/j.1471-4159.2002.01253.x  1
2002 da Silva JS, Dotti CG. Breaking the neuronal sphere: regulation of the actin cytoskeleton in neuritogenesis. Nature Reviews. Neuroscience. 3: 694-704. PMID 12209118 DOI: 10.1038/nrn918  1
2001 Rodriguez JA, Piddini E, Hasegawa T, Miyagi T, Dotti CG. Plasma membrane ganglioside sialidase regulates axonal growth and regeneration in hippocampal neurons in culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 8387-95. PMID 11606627  1
2001 Jun L, Frints S, Duhamel H, Herold A, Abad-Rodrigues J, Dotti C, Izaurralde E, Marynen P, Froyen G. NXF5, a novel member of the nuclear RNA export factor family, is lost in a male patient with a syndromic form of mental retardation. Current Biology : Cb. 11: 1381-91. PMID 11566096 DOI: 10.1016/S0960-9822(01)00419-5  1
2001 Piddini E, Schmid JA, de Martin R, Dotti CG. The Ras-like GTPase Gem is involved in cell shape remodelling and interacts with the novel kinesin-like protein KIF9. The Embo Journal. 20: 4076-87. PMID 11483511 DOI: 10.1093/emboj/20.15.4076  1
2001 Babià T, Ledesma MD, Saffrich R, Kok JW, Dotti CG, Egea G. Endocytosis of NBD-sphingolipids in neurons: exclusion from degradative compartments and transport to the Golgi complex. Traffic (Copenhagen, Denmark). 2: 395-405. PMID 11389767 DOI: 10.1034/j.1600-0854.2001.002006395.x  1
2000 Ledesma MD, Da Silva JS, Crassaerts K, Delacourte A, De Strooper B, Dotti CG. Brain plasmin enhances APP alpha-cleavage and Abeta degradation and is reduced in Alzheimer's disease brains. Embo Reports. 1: 530-5. PMID 11263499 DOI: 10.1093/embo-reports/kvd107  1
2000 Sánchez Martin C, Ledesma D, Dotti CG, Avila J. Microtubule-associated protein-2 located in growth regions of rat hippocampal neurons is highly phosphorylated at its proline-rich region. Neuroscience. 101: 885-93. PMID 11113337 DOI: 10.1016/S0306-4522(00)00434-6  1
2000 Bradke F, Dotti CG. Differentiated neurons retain the capacity to generate axons from dendrites. Current Biology : Cb. 10: 1467-70. PMID 11102812 DOI: 10.1016/S0960-9822(00)00807-1  1
2000 Bradke F, Dotti CG. Establishment of neuronal polarity: lessons from cultured hippocampal neurons. Current Opinion in Neurobiology. 10: 574-81. PMID 11084319 DOI: 10.1016/S0959-4388(00)00124-0  1
2000 Wilson JM, de Hoop M, Zorzi N, Toh BH, Dotti CG, Parton RG. EEA1, a tethering protein of the early sorting endosome, shows a polarized distribution in hippocampal neurons, epithelial cells, and fibroblasts. Molecular Biology of the Cell. 11: 2657-71. PMID 10930461  1
2000 Ruberti F, Dotti CG. Involvement of the proximal C terminus of the AMPA receptor subunit GluR1 in dendritic sorting. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: RC78. PMID 10807936  1
2000 Bagni C, Mannucci L, Dotti CG, Amaldi F. Chemical stimulation of synaptosomes modulates alpha -Ca2+/calmodulin-dependent protein kinase II mRNA association to polysomes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: RC76. PMID 10783400  1
2000 Kaether C, Skehel P, Dotti CG. Axonal membrane proteins are transported in distinct carriers: a two-color video microscopy study in cultured hippocampal neurons. Molecular Biology of the Cell. 11: 1213-24. PMID 10749925  1
2000 Poyatos I, Ruberti F, Martínez-Maza R, Giménez C, Dotti CG, Zafra F. Polarized distribution of glycine transporter isoforms in epithelial and neuronal cells. Molecular and Cellular Neurosciences. 15: 99-111. PMID 10662509 DOI: 10.1006/mcne.1999.0807  1
2000 Bradke F, Dotti CG. Changes in membrane trafficking and actin dynamics during axon formation in cultured hippocampal neurons. Microscopy Research and Technique. 48: 3-11. PMID 10620780 DOI: 10.1002/(SICI)1097-0029(20000101)48:1<3::AID-JEMT2>3.0.CO;2-O  1
1999 Jensen PH, Li JY, Dahlström A, Dotti CG. Axonal transport of synucleins is mediated by all rate components. The European Journal of Neuroscience. 11: 3369-76. PMID 10564344 DOI: 10.1046/j.1460-9568.1999.00754.x  1
1999 Gieffers C, Peters BH, Kramer ER, Dotti CG, Peters JM. Expression of the CDH1-associated form of the anaphase-promoting complex in postmitotic neurons. Proceedings of the National Academy of Sciences of the United States of America. 96: 11317-22. PMID 10500174 DOI: 10.1073/pnas.96.20.11317  1
1999 Köhrmann M, Luo M, Kaether C, DesGroseillers L, Dotti CG, Kiebler MA. Microtubule-dependent recruitment of Staufen-green fluorescent protein into large RNA-containing granules and subsequent dendritic transport in living hippocampal neurons. Molecular Biology of the Cell. 10: 2945-53. PMID 10473638  1
1999 Ledesma MD, Brügger B, Bünning C, Wieland FT, Dotti CG. Maturation of the axonal plasma membrane requires upregulation of sphingomyelin synthesis and formation of protein-lipid complexes. The Embo Journal. 18: 1761-71. PMID 10202140 DOI: 10.1093/emboj/18.7.1761  1
1999 Bradke F, Dotti CG. The role of local actin instability in axon formation. Science (New York, N.Y.). 283: 1931-4. PMID 10082468  1
1999 Kiebler MA, Hemraj I, Verkade P, Köhrmann M, Fortes P, Marión RM, Ortín J, Dotti CG. The mammalian staufen protein localizes to the somatodendritic domain of cultured hippocampal neurons: implications for its involvement in mRNA transport. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 19: 288-97. PMID 9870958  1
1998 Santama N, Krijnse-Locker J, Griffiths G, Noda Y, Hirokawa N, Dotti CG. KIF2beta, a new kinesin superfamily protein in non-neuronal cells, is associated with lysosomes and may be implicated in their centrifugal translocation. The Embo Journal. 17: 5855-67. PMID 9774330 DOI: 10.1093/emboj/17.20.5855  1
1998 Jensen PH, Nielsen MS, Jakes R, Dotti CG, Goedert M. Binding of alpha-synuclein to brain vesicles is abolished by familial Parkinson's disease mutation. The Journal of Biological Chemistry. 273: 26292-4. PMID 9756856 DOI: 10.1074/jbc.273.41.26292  1
1998 Bradke F, Dotti CG. Membrane traffic in polarized neurons. Biochimica Et Biophysica Acta. 1404: 245-58. PMID 9714822 DOI: 10.1016/S0167-4889(98)00060-3  1
1998 Simons M, Keller P, De Strooper B, Beyreuther K, Dotti CG, Simons K. Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 95: 6460-4. PMID 9600988 DOI: 10.1073/pnas.95.11.6460  1
1998 Ledesma MD, Simons K, Dotti CG. Neuronal polarity: essential role of protein-lipid complexes in axonal sorting. Proceedings of the National Academy of Sciences of the United States of America. 95: 3966-71. PMID 9520476 DOI: 10.1073/pnas.95.7.3966  1
1997 Bradke F, Dotti CG. Neuronal polarity: vectorial cytoplasmic flow precedes axon formation. Neuron. 19: 1175-86. PMID 9427242 DOI: 10.1016/S0896-6273(00)80410-9  1
1997 Hémar A, Olivo JC, Williamson E, Saffrich R, Dotti CG. Dendroaxonal transcytosis of transferrin in cultured hippocampal and sympathetic neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 9026-34. PMID 9364049  1
1997 Hartmann T, Bieger SC, Brühl B, Tienari PJ, Ida N, Allsop D, Roberts GW, Masters CL, Dotti CG, Unsicker K, Beyreuther K. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nature Medicine. 3: 1016-20. PMID 9288729 DOI: 10.1038/nm0997-1016  1
1997 Tienari PJ, Ida N, Ikonen E, Simons M, Weidemann A, Multhaup G, Masters CL, Dotti CG, Beyreuther K. Intracellular and secreted Alzheimer beta-amyloid species are generated by distinct mechanisms in cultured hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 94: 4125-30. PMID 9108116 DOI: 10.1073/pnas.94.8.4125  1
1996 Tienari PJ, De Strooper B, Ikonen E, Ida N, Simons M, Masters CL, Dotti CG, Beyreuther K. Neuronal sorting and processing of amyloid precursor protein: implications for Alzheimer's disease. Cold Spring Harbor Symposia On Quantitative Biology. 61: 575-85. PMID 9246484  1
1996 Tienari PJ, De Strooper B, Ikonen E, Simons M, Weidemann A, Czech C, Hartmann T, Ida N, Multhaup G, Masters CL, Van Leuven F, Beyreuther K, Dotti CG. The beta-amyloid domain is essential for axonal sorting of amyloid precursor protein. The Embo Journal. 15: 5218-29. PMID 8895567  1
1996 Simons M, de Strooper B, Multhaup G, Tienari PJ, Dotti CG, Beyreuther K. Amyloidogenic processing of the human amyloid precursor protein in primary cultures of rat hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 899-908. PMID 8558258  1
1995 Huber LA, Dupree P, Dotti CG. Use of antisense oligonucleotides to study Rab function in vivo. Methods in Enzymology. 257: 302-12. PMID 8583934 DOI: 10.1016/S0076-6879(95)57034-9  1
1995 Krijnse-Locker J, Parton RG, Fuller SD, Griffiths G, Dotti CG. The organization of the endoplasmic reticulum and the intermediate compartment in cultured rat hippocampal neurons. Molecular Biology of the Cell. 6: 1315-32. PMID 8573789  1
1995 Huber LA, Dupree P, Dotti CG. A deficiency of the small GTPase rab8 inhibits membrane traffic in developing neurons. Molecular and Cellular Biology. 15: 918-24. PMID 7823956  1
1995 Cid-Arregui A, Parton RG, Simons K, Dotti CG. Nocodazole-dependent transport, and brefeldin A--sensitive processing and sorting, of newly synthesized membrane proteins in cultured neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 4259-69. PMID 7790910  1
1995 Simons M, Ikonen E, Tienari PJ, Cid-Arregui A, Mönning U, Beyreuther K, Dotti CG. Intracellular routing of human amyloid protein precursor: axonal delivery followed by transport to the dendrites. Journal of Neuroscience Research. 41: 121-8. PMID 7674373 DOI: 10.1002/jnr.490410114  1
1995 Simons M, Tienari PJ, Dotti CG, Beyreuther K. Two-dimensional gel mapping of the processing of the human amyloid precursor protein in rat hippocampal neurons. Febs Letters. 368: 363-6. PMID 7628638 DOI: 10.1016/0014-5793(95)00654-R  1
1995 De Strooper B, Simons M, Multhaup G, Van Leuven F, Beyreuther K, Dotti CG. Production of intracellular amyloid-containing fragments in hippocampal neurons expressing human amyloid precursor protein and protection against amyloidogenesis by subtle amino acid substitutions in the rodent sequence. The Embo Journal. 14: 4932-8. PMID 7588622  1
1995 de Hoop M, von Poser C, Lange C, Ikonen E, Hunziker W, Dotti CG. Intracellular routing of wild-type and mutated polymeric immunoglobulin receptor in hippocampal neurons in culture. The Journal of Cell Biology. 130: 1447-59. PMID 7559765 DOI: 10.1083/jcb.130.6.1447  1
1994 de Hoop MJ, Olkkonen VM, Ikonen E, Williamson E, von Poser C, Meyn L, Dotti CG. Semliki Forest virus as a tool for protein expression in cultured rat hippocampal neurons. Gene Therapy. 1: S28-31. PMID 8542389  1
1994 de Hoop MJ, Huber LA, Stenmark H, Williamson E, Zerial M, Parton RG, Dotti CG. The involvement of the small GTP-binding protein Rab5a in neuronal endocytosis. Neuron. 13: 11-22. PMID 8043272 DOI: 10.1016/0896-6273(94)90456-1  1
1993 Ikonen E, Parton RG, Hunziker W, Simons K, Dotti CG. Transcytosis of the polymeric immunoglobulin receptor in cultured hippocampal neurons. Current Biology : Cb. 3: 635-44. PMID 15335854 DOI: 10.1016/0960-9822(93)90061-R  1
1993 Dotti CG, Kartenbeck J, Simons K. Polarized distribution of the viral glycoproteins of vesicular stomatitis, fowl plague and Semliki Forest viruses in hippocampal neurons in culture: a light and electron microscopy study. Brain Research. 610: 141-7. PMID 8390907 DOI: 10.1016/0006-8993(93)91227-J  1
1993 Olkkonen VM, Liljeström P, Garoff H, Simons K, Dotti CG. Expression of heterologous proteins in cultured rat hippocampal neurons using the Semliki Forest virus vector. Journal of Neuroscience Research. 35: 445-51. PMID 8360951 DOI: 10.1002/jnr.490350412  1
1993 Djabali K, Zissopoulou A, de Hoop MJ, Georgatos SD, Dotti CG. Peripherin expression in hippocampal neurons induced by muscle soluble factor(s). The Journal of Cell Biology. 123: 1197-206. PMID 8245126  1
1993 de Hoop MJ, Dotti CG. Membrane traffic in polarized neurons in culture. Journal of Cell Science. Supplement. 17: 85-92. PMID 8144707  1
1993 Parton RG, Dotti CG. Cell biology of neuronal endocytosis. Journal of Neuroscience Research. 36: 1-9. PMID 7693962 DOI: 10.1002/jnr.490360102  1
1992 Parton RG, Simons K, Dotti CG. Axonal and dendritic endocytic pathways in cultured neurons. The Journal of Cell Biology. 119: 123-37. PMID 1527164 DOI: 10.1016/0739-6260(92)90095-U  1
1992 Van Lookeren Campagne M, Dotti CG, Jap Tjoen San ER, Verkleij AJ, Gispen WH, Oestreicher AB. B-50/GAP43 localization in polarized hippocampal neurons in vitro: an ultrastructural quantitative study. Neuroscience. 50: 35-52. PMID 1407559 DOI: 10.1016/0306-4522(92)90380-K  1
1992 Kobayashi T, Storrie B, Simons K, Dotti CG. A functional barrier to movement of lipids in polarized neurons. Nature. 359: 647-50. PMID 1406997 DOI: 10.1038/359647a0  1
1992 Van Lookeren Campagne M, Dotti CG, Verkleij AJ, Gispen WH, Oestreicher AB. B-50/GAP43 localization on membranes of putative transport vesicles in the cell body, neurites and growth cones of cultured hippocampal neurons. Neuroscience Letters. 137: 129-32. PMID 1385647 DOI: 10.1016/0304-3940(92)90314-W  1
1992 van Lookeren Campagne M, Dotti CG, Verkleij AJ, Gispen WH, Oestreicher AB. Redistribution of B-50/growth-associated protein 43 during differentiation and maturation of rat hippocampal neurons in vitro. Neuroscience. 51: 601-19. PMID 1336822 DOI: 10.1016/0306-4522(92)90300-Q  1
1991 Parton RG, Dotti CG, Bacallao R, Kurtz I, Simons K, Prydz K. pH-induced microtubule-dependent redistribution of late endosomes in neuronal and epithelial cells. The Journal of Cell Biology. 113: 261-74. PMID 2010463  1
1991 Dotti CG, Banker G. Intracellular organization of hippocampal neurons during the development of neuronal polarity. Journal of Cell Science. Supplement. 15: 75-84. PMID 1824109  1
1991 Huttner WB, Dotti CG. Exocytotic and endocytotic membrane traffic in neurons. Current Opinion in Neurobiology. 1: 388-92. PMID 1821682 DOI: 10.1016/0959-4388(91)90058-F  1
1991 Dotti CG, Parton RG, Simons K. Polarized sorting of glypiated proteins in hippocampal neurons. Nature. 349: 158-61. PMID 1670898 DOI: 10.1038/349158a0  1
1991 Killisch I, Dotti CG, Laurie DJ, Lüddens H, Seeburg PH. Expression patterns of GABAA receptor subtypes in developing hippocampal neurons. Neuron. 7: 927-36. PMID 1662520 DOI: 10.1016/0896-6273(91)90338-Z  1
1990 Dotti CG, Simons K. Polarized sorting of viral glycoproteins to the axon and dendrites of hippocampal neurons in culture. Cell. 62: 63-72. PMID 2163770 DOI: 10.1016/0092-8674(90)90240-F  1
1988 Dotti CG, Sullivan CA, Banker GA. The establishment of polarity by hippocampal neurons in culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 8: 1454-68. PMID 3282038  1
1987 Dotti CG, Banker GA. Experimentally induced alteration in the polarity of developing neurons. Nature. 330: 254-6. PMID 3313064 DOI: 10.1038/330254a0  1
1987 Dotti CG, Banker GA, Binder LI. The expression and distribution of the microtubule-associated proteins tau and microtubule-associated protein 2 in hippocampal neurons in the rat in situ and in cell culture. Neuroscience. 23: 121-30. PMID 3120034 DOI: 10.1016/0306-4522(87)90276-4  1
1984 Dotti CG, Taleisnik S. Blockade of the release of LH induced by pharmacological suppression of adrenergic inflow into the locus coeruleus. European Journal of Pharmacology. 99: 9-14. PMID 6327337 DOI: 10.1016/0014-2999(84)90426-6  1
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