Neil A. Shneider - Publications

Affiliations: 
Neurobiology and Behavior Columbia University, New York, NY 
Area:
Neuroscience Biology

33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Korobeynikov VA, Lyashchenko AK, Blanco-Redondo B, Jafar-Nejad P, Shneider NA. Antisense oligonucleotide silencing of FUS expression as a therapeutic approach in amyotrophic lateral sclerosis. Nature Medicine. 28: 104-116. PMID 35075293 DOI: 10.1038/s41591-021-01615-z  0.628
2020 Garcia-Diaz A, Efe G, Kabra K, Patel A, Lowry ER, Shneider N, Corneo B, Wichterle H. Standardized reporter systems for purification and imaging of human pluripotent stem cell-derived motor neurons and other cholinergic cells. Neuroscience. PMID 32615233 DOI: 10.1016/J.Neuroscience.2020.06.028  0.388
2020 Tsai YL, Coady TH, Lu L, Zheng D, Alland I, Tian B, Shneider NA, Manley JL. ALS/FTD-associated protein FUS induces mitochondrial dysfunction by preferentially sequestering respiratory chain complex mRNAs. Genes & Development. PMID 32381627 DOI: 10.1101/Gad.335836.119  0.34
2020 Kankel MW, Sen A, Lu L, Theodorou M, Dimlich DN, McCampbell A, Henderson CE, Shneider NA, Artavanis-Tsakonas S. Amyotrophic Lateral Sclerosis Modifiers in Reveal the Phospholipase D Pathway as a Potential Therapeutic Target. Genetics. PMID 32345615 DOI: 10.1534/Genetics.119.302985  0.397
2019 Nwabuobi L, Tomishon D, Shneider NA, Fahn S, Vonsattel JP, Cortes E. Multiple System Atrophy With Predominant Striatonigral Degeneration and TAR DNA-Binding Protein of 43 kDa Pathology: An Unusual Variant of Multiple System Atrophy. Movement Disorders Clinical Practice. 6: 661-666. PMID 31745474 DOI: 10.1002/Mdc3.12823  0.323
2019 Gelfman S, Dugger SA, Araujo Martins Moreno C, Ren Z, Wolock CJ, Shneider N, Phatnani H, Cirulli ET, Lasseigne BN, Harris T, Maniatis T, Rouleau G, Brown RH, Gitler AD, Myers RM, et al. A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS. Genome Research. PMID 30940688 DOI: 10.1101/Gr.243592.118  0.337
2019 Dermentzaki G, Politi KA, Lu L, Mishra V, Pérez-Torres EJ, Sosunov AA, McKhann GM, Lotti F, Shneider NA, Przedborski S. Deletion of Prevents Motor Neuron Death but not . Eneuro. 6. PMID 30815534 DOI: 10.1523/ENEURO.0308-18.2018  0.356
2019 Ebstein SY, Yagudayeva I, Shneider NA. Mutant TDP-43 Causes Early-Stage Dose-Dependent Motor Neuron Degeneration in a TARDBP Knockin Mouse Model of ALS. Cell Reports. 26: 364-373.e4. PMID 30625319 DOI: 10.1016/J.Celrep.2018.12.045  0.469
2018 Conlon EG, Fagegaltier D, Agius P, Davis-Porada J, Gregory J, Hubbard I, Kang K, Kim D, Phatnani H, Shneider NA, Manley JL. Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism. Elife. 7. PMID 30003873 DOI: 10.7554/Elife.37754  0.375
2018 Martinez-Silva ML, Imhoff-Manuel RD, Sharma A, Heckman CJ, Shneider NA, Roselli F, Zytnicki D, Manuel M. Hypoexcitability precedes denervation in the large fast-contracting motor units in two unrelated mouse models of ALS. Elife. 7. PMID 29580378 DOI: 10.7554/Elife.30955  0.438
2018 Biscarini S, Capauto D, Peruzzi G, Lu L, Colantoni A, Santini T, Shneider NA, Caffarelli E, Laneve P, Bozzoni I. Characterization of the lncRNA transcriptome in mESC-derived motor neurons: Implications for FUS-ALS. Stem Cell Research. PMID 29449089 DOI: 10.1016/J.Scr.2018.01.037  0.405
2018 Capauto D, Colantoni A, Lu L, Santini T, Peruzzi G, Biscarini S, Morlando M, Shneider NA, Caffarelli E, Laneve P, Bozzoni I. A Regulatory Circuitry Between Gria2, miR-409, and miR-495 Is Affected by ALS FUS Mutation in ESC-Derived Motor Neurons. Molecular Neurobiology. PMID 29430619 DOI: 10.1007/S12035-018-0884-4  0.404
2018 Conlon EG, Fagegaltier D, Agius P, Davis-Porada J, Gregory J, Hubbard I, Kang K, Kim D, Phatnani H, Kwan J, Sareen D, Broach JR, Simmons Z, Arcila-Londono X, Lee EB, ... ... Shneider NA, et al. Author response: Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism Elife. DOI: 10.7554/Elife.37754.025  0.346
2018 Martínez-Silva MdL, Imhoff-Manuel RD, Sharma A, Heckman C, Shneider NA, Roselli F, Zytnicki D, Manuel M. Author response: Hypoexcitability precedes denervation in the large fast-contracting motor units in two unrelated mouse models of ALS Elife. DOI: 10.7554/Elife.30955.019  0.389
2017 Errichelli L, Dini Modigliani S, Laneve P, Colantoni A, Legnini I, Capauto D, Rosa A, De Santis R, Scarfò R, Peruzzi G, Lu L, Caffarelli E, Shneider NA, Morlando M, Bozzoni I. FUS affects circular RNA expression in murine embryonic stem cell-derived motor neurons. Nature Communications. 8: 14741. PMID 28358055 DOI: 10.1038/Ncomms14741  0.435
2016 Lalancette-Hebert M, Sharma A, Lyashchenko AK, Shneider NA. Gamma motor neurons survive and exacerbate alpha motor neuron degeneration in ALS. Proceedings of the National Academy of Sciences of the United States of America. PMID 27930290 DOI: 10.1073/Pnas.1605210113  0.623
2016 Tian F, Yang W, Mordes DA, Wang JY, Salameh JS, Mok J, Chew J, Sharma A, Leno-Duran E, Suzuki-Uematsu S, Suzuki N, Han SS, Lu FK, Ji M, Zhang R, ... ... Shneider NA, et al. Monitoring peripheral nerve degeneration in ALS by label-free stimulated Raman scattering imaging. Nature Communications. 7: 13283. PMID 27796305 DOI: 10.1038/Ncomms13283  0.348
2016 Conlon EG, Lu L, Sharma A, Yamazaki T, Tang T, Shneider NA, Manley JL. The C9ORF72 GGGGCC expansion forms RNA G-quadruplex inclusions and sequesters hnRNP H to disrupt splicing in ALS patient brains. Elife. 5. PMID 27623008 DOI: 10.7554/Elife.17820  0.303
2016 Sharma A, Lyashchenko AK, Lu L, Nasrabady SE, Elmaleh M, Mendelsohn M, Nemes A, Tapia JC, Mentis GZ, Shneider NA. ALS-associated mutant FUS induces selective motor neuron degeneration through toxic gain of function. Nature Communications. 7: 10465. PMID 26842965 DOI: 10.1038/Ncomms10465  0.643
2015 Siembab VC, Gomez-Perez L, Rotterman TM, Shneider NA, Alvarez FJ. Role of primary afferents in the developmental regulation of motor axon synapse numbers on Renshaw cells. The Journal of Comparative Neurology. PMID 26660356 DOI: 10.1002/Cne.23946  0.325
2015 Murakami T, Qamar S, Lin JQ, Schierle GS, Rees E, Miyashita A, Costa AR, Dodd RB, Chan FT, Michel CH, Kronenberg-Versteeg D, Li Y, Yang SP, Wakutani Y, Meadows W, ... ... Shneider NA, et al. ALS/FTD Mutation-Induced Phase Transition of FUS Liquid Droplets and Reversible Hydrogels into Irreversible Hydrogels Impairs RNP Granule Function. Neuron. PMID 26526393 DOI: 10.1016/J.Neuron.2015.10.030  0.348
2015 Cirulli ET, Lasseigne BN, Petrovski S, Sapp PC, Dion PA, Leblond CS, Couthouis J, Lu YF, Wang Q, Krueger BJ, Ren Z, Keebler J, Han Y, Levy SE, Boone BE, ... ... Shneider NA, et al. Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways. Science (New York, N.Y.). 347: 1436-41. PMID 25700176 DOI: 10.1126/Science.Aaa3650  0.368
2014 Wen X, Tan W, Westergard T, Krishnamurthy K, Markandaiah SS, Shi Y, Lin S, Shneider NA, Monaghan J, Pandey UB, Pasinelli P, Ichida JK, Trotti D. Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death. Neuron. 84: 1213-25. PMID 25521377 DOI: 10.1016/J.Neuron.2014.12.010  0.47
2012 Yamazaki T, Chen S, Yu Y, Yan B, Haertlein TC, Carrasco MA, Tapia JC, Zhai B, Das R, Lalancette-Hebert M, Sharma A, Chandran S, Sullivan G, Nishimura AL, Shaw CE, ... ... Shneider NA, et al. FUS-SMN protein interactions link the motor neuron diseases ALS and SMA. Cell Reports. 2: 799-806. PMID 23022481 DOI: 10.1016/J.Celrep.2012.08.025  0.496
2012 Ashrafi S, Lalancette-Hébert M, Friese A, Sigrist M, Arber S, Shneider NA, Kaltschmidt JA. Wnt7A identifies embryonic γ-motor neurons and reveals early postnatal dependence of γ-motor neurons on a muscle spindle-derived signal. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 8725-31. PMID 22723712 DOI: 10.1523/Jneurosci.1160-12.2012  0.406
2011 Wang JW, Brent JR, Tomlinson A, Shneider NA, McCabe BD. The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span. The Journal of Clinical Investigation. 121: 4118-26. PMID 21881207 DOI: 10.1172/Jci57883  0.497
2010 Mentis GZ, Alvarez FJ, Shneider NA, Siembab VC, O'Donovan MJ. Mechanisms regulating the specificity and strength of muscle afferent inputs in the spinal cord. Annals of the New York Academy of Sciences. 1198: 220-30. PMID 20536937 DOI: 10.1111/J.1749-6632.2010.05538.X  0.385
2009 Shneider NA, Brown MN, Smith CA, Pickel J, Alvarez FJ. Gamma motor neurons express distinct genetic markers at birth and require muscle spindle-derived GDNF for postnatal survival. Neural Development. 4: 42. PMID 19954518 DOI: 10.1186/1749-8104-4-42  0.386
2009 Shneider NA, Mentis GZ, Schustak J, O'Donovan MJ. Functionally reduced sensorimotor connections form with normal specificity despite abnormal muscle spindle development: the role of spindle-derived neurotrophin 3. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 4719-35. PMID 19369542 DOI: 10.1523/Jneurosci.5790-08.2009  0.389
2006 Mentis GZ, Gravell M, Hamilton R, Shneider NA, O'Donovan MJ, Schubert M. Transduction of motor neurons and muscle fibers by intramuscular injection of HIV-1-based vectors pseudotyped with select rabies virus glycoproteins. Journal of Neuroscience Methods. 157: 208-17. PMID 16725205 DOI: 10.1016/J.Jneumeth.2006.04.011  0.387
2002 Hippenmeyer S, Shneider NA, Birchmeier C, Burden SJ, Jessell TM, Arber S. A role for neuregulin1 signaling in muscle spindle differentiation. Neuron. 36: 1035-49. PMID 12495620 DOI: 10.1016/S0896-6273(02)01101-7  0.308
1992 Nakanishi N, Axel R, Shneider NA. Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors. Proceedings of the National Academy of Sciences of the United States of America. 89: 8552-6. PMID 1388270 DOI: 10.1073/Pnas.89.18.8552  0.645
1990 Nakanishi N, Shneider NA, Axel R. A family of glutamate receptor genes: evidence for the formation of heteromultimeric receptors with distinct channel properties. Neuron. 5: 569-81. PMID 1699567 DOI: 10.1016/0896-6273(90)90212-X  0.637
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