| Year |
Citation |
Score |
| 2024 |
Seong M, Bak-Gordon P, Liu Z, Canoll PD, Manley JL. Splicing dysregulation in glioblastoma alters the function of cell migration-related genes. Glia. PMID 39448549 DOI: 10.1002/glia.24630 |
0.302 |
|
| 2024 |
Liu L, Manley JL. Modulation of diverse biological processes by CPSF, the master regulator of mRNA 3' ends. Rna (New York, N.Y.). PMID 38986572 DOI: 10.1261/rna.080108.124 |
0.341 |
|
| 2023 |
Feng S, Desotell A, Ross A, Jovanovic M, Manley JL. A nucleolar long "non-coding" RNA encodes a novel protein that functions in response to stress. Proceedings of the National Academy of Sciences of the United States of America. 120: e2221109120. PMID 36812203 DOI: 10.1073/pnas.2221109120 |
0.386 |
|
| 2022 |
Zhang J, Huang J, Xu K, Xing P, Huang Y, Liu Z, Tong L, Manley JL. DHX15 is involved in SUGP1-mediated RNA missplicing by mutant SF3B1 in cancer. Proceedings of the National Academy of Sciences of the United States of America. 119: e2216712119. PMID 36459648 DOI: 10.1073/pnas.2216712119 |
0.337 |
|
| 2022 |
Feng S, Manley JL. Beyond rRNA: nucleolar transcription generates a complex network of RNAs with multiple roles in maintaining cellular homeostasis. Genes & Development. 36: 876-886. PMID 36207140 DOI: 10.1101/gad.349969.122 |
0.406 |
|
| 2022 |
Tsai YL, Mu YC, Manley JL. Nuclear RNA transcript levels modulate nucleocytoplasmic distribution of ALS/FTD-associated protein FUS. Scientific Reports. 12: 8180. PMID 35581240 DOI: 10.1038/s41598-022-12098-4 |
0.396 |
|
| 2021 |
Yamazaki T, Liu L, Manley JL. Oxidative stress induces Ser 2 dephosphorylation of the RNA polymerase II CTD and premature transcription termination. Transcription. 1-17. PMID 34874799 DOI: 10.1080/21541264.2021.2009421 |
0.347 |
|
| 2021 |
Feng S, Manley JL. Replication protein A associates with nucleolar R loops and regulates rRNA transcription and nucleolar morphology. Genes & Development. PMID 34819354 DOI: 10.1101/gad.348858.121 |
0.377 |
|
| 2020 |
Wang Q, Conlon E, Manley J, Rio D. Widespread intron retention impairs protein homeostasis in C9orf72 ALS brains. Genome Research. PMID 33055097 DOI: 10.1101/gr.265298.120 |
0.308 |
|
| 2020 |
Richard P, Feng S, Tsai YL, Li W, Rinchetti P, Muhith U, Irizarry-Cole J, Stolz K, Sanz LA, Hartono S, Hoque M, Tadesse S, Seitz H, Lotti F, Hirano M, ... ... Manley JL, et al. SETX (senataxin), the helicase mutated in AOA2 and ALS4, functions in autophagy regulation. Autophagy. PMID 32686621 DOI: 10.1080/15548627.2020.1796292 |
0.428 |
|
| 2020 |
Cheng LC, Zheng D, Baljinnyam E, Sun F, Ogami K, Yeung PL, Hoque M, Lu CW, Manley JL, Tian B. Widespread transcript shortening through alternative polyadenylation in secretory cell differentiation. Nature Communications. 11: 3182. PMID 32576858 DOI: 10.1038/S41467-020-16959-2 |
0.397 |
|
| 2020 |
Yamazaki T, Liu L, Colon EG, Manley JL. Burkitt-lymphoma-related mutations alter TCF3 alternative splicing by disrupting hnRNPH1 binding. Rna Biology. PMID 32449435 DOI: 10.1080/15476286.2020.1772559 |
0.339 |
|
| 2020 |
Tsai YL, Coady TH, Lu L, Zheng D, Alland I, Tian B, Shneider NA, Manley JL. ALS/FTD-associated protein FUS induces mitochondrial dysfunction by preferentially sequestering respiratory chain complex mRNAs. Genes & Development. PMID 32381627 DOI: 10.1101/Gad.335836.119 |
0.371 |
|
| 2019 |
Zhang J, Ali AM, Lieu YK, Liu Z, Gao J, Rabadan R, Raza A, Mukherjee S, Manley JL. Disease-Causing Mutations in SF3B1 Alter Splicing by Disrupting Interaction with SUGP1. Molecular Cell. PMID 31474574 DOI: 10.1016/J.Molcel.2019.07.017 |
0.368 |
|
| 2019 |
Yamazaki T, Liu L, Manley JL. TCF3 Mutually Exclusive Alternative Splicing Is Controlled by Long Range Cooperative Actions between hnRNPH1 and PTBP1. Rna (New York, N.Y.). PMID 31391218 DOI: 10.1261/Rna.072298.119 |
0.458 |
|
| 2019 |
Wang X, Goodrich KJ, Conlon EG, Gao J, Erbse AH, Manley JL, Cech TR. C9orf72 and Triplet Repeat Disorder RNAs: G-quadruplex formation, binding to PRC2 and implications for disease mechanisms. Rna (New York, N.Y.). PMID 31048495 DOI: 10.1261/Rna.071191.119 |
0.435 |
|
| 2018 |
Fomin V, Richard P, Hoque M, Li C, Gu Z, Fissore-O'Leary M, Tian B, Prives C, Manley JL. The gene, implicated in ALS/FTD, encodes a protein that functions in control of endothelin and glutamate signaling. Molecular and Cellular Biology. PMID 30150298 DOI: 10.1128/Mcb.00155-18 |
0.341 |
|
| 2018 |
Yamazaki T, Liu L, Lazarev D, Al-Zain A, Fomin V, Yeung PL, Chambers SM, Lu CW, Studer L, Manley JL. TCF3 alternative splicing controlled by hnRNP H/F regulates E-cadherin expression and hESC pluripotency. Genes & Development. PMID 30115631 DOI: 10.1101/Gad.316984.118 |
0.305 |
|
| 2018 |
Conlon EG, Fagegaltier D, Agius P, Davis-Porada J, Gregory J, Hubbard I, Kang K, Kim D, Phatnani H, Shneider NA, Manley JL. Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism. Elife. 7. PMID 30003873 DOI: 10.7554/Elife.37754 |
0.306 |
|
| 2018 |
Richard P, Ogami K, Chen Y, Feng S, Moresco JJ, Yates JR, Manley JL. NRDE-2, the human homolog of fission yeast Nrl1, prevents DNA damage accumulation in human cells. Rna Biology. PMID 29902117 DOI: 10.1080/15476286.2018.1467180 |
0.438 |
|
| 2018 |
Ogami K, Chen Y, Manley JL. RNA surveillance by the nuclear RNA exosome: mechanisms and significance. Non-Coding Rna. 4. PMID 29629374 DOI: 10.3390/Ncrna4010008 |
0.447 |
|
| 2018 |
Conlon EG, Fagegaltier D, Agius P, Davis-Porada J, Gregory J, Hubbard I, Kang K, Kim D, Phatnani H, Kwan J, Sareen D, Broach JR, Simmons Z, Arcila-Londono X, Lee EB, ... ... Manley JL, et al. Author response: Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism Elife. DOI: 10.7554/Elife.37754.025 |
0.502 |
|
| 2017 |
Yurko N, Liu X, Yamazaki T, Hoque M, Tian B, Manley JL. MPK1/SLT2 Links Multiple Stress Responses with Gene Expression in Budding Yeast by Phosphorylating Tyr1 of the RNAP II CTD. Molecular Cell. 68: 913-925.e3. PMID 29220656 DOI: 10.1016/J.Molcel.2017.11.020 |
0.386 |
|
| 2017 |
Sun Y, Zhang Y, Hamilton K, Manley JL, Shi Y, Walz T, Tong L. Molecular basis for the recognition of the human AAUAAA polyadenylation signal. Proceedings of the National Academy of Sciences of the United States of America. PMID 29208711 DOI: 10.1073/Pnas.1718723115 |
0.353 |
|
| 2017 |
Conlon EG, Manley JL. Erratum: RNA-binding proteins in neurodegeneration: mechanisms in aggregate. Genes & Development. 31: 2015. PMID 29089423 DOI: 10.1101/Gad.308205.117 |
0.41 |
|
| 2017 |
Ogami K, Manley JL. Mtr4/ZFC3H1 protects polysomes through nuclear RNA surveillance. Cell Cycle (Georgetown, Tex.). 0. PMID 28933589 DOI: 10.1080/15384101.2017.1377501 |
0.405 |
|
| 2017 |
Liu X, Hoque M, Larochelle M, Lemay JF, Yurko N, Manley JL, Bachand F, Tian B. Comparative analysis of alternative polyadenylation in S. cerevisiae and S. pombe. Genome Research. PMID 28916539 DOI: 10.1101/Gr.222331.117 |
0.347 |
|
| 2017 |
Conlon EG, Manley JL. RNA-binding proteins in neurodegeneration: mechanisms in aggregate. Genes & Development. 31: 1509-1528. PMID 28912172 DOI: 10.1101/Gad.304055.117 |
0.385 |
|
| 2017 |
Yurko NM, Manley JL. The RNA polymerase II CTD "orphan" residues: Emerging insights into the functions of Tyr-1, Thr-4 and Ser-7. Transcription. 0. PMID 28771071 DOI: 10.1080/21541264.2017.1338176 |
0.396 |
|
| 2017 |
Ogami K, Richard P, Chen Y, Hoque M, Li W, Moresco JJ, Yates JR, Tian B, Manley JL. An Mtr4/ZFC3H1 complex facilitates turnover of unstable nuclear RNAs to prevent their cytoplasmic transport and global translational repression. Genes & Development. PMID 28733371 DOI: 10.1101/Gad.302604.117 |
0.48 |
|
| 2017 |
Richard P, Vethantham V, Manley JL. Roles of Sumoylation in mRNA Processing and Metabolism. Advances in Experimental Medicine and Biology. 963: 15-33. PMID 28197904 DOI: 10.1007/978-3-319-50044-7_2 |
0.442 |
|
| 2016 |
Shkreta L, Toutant J, Durand M, Manley JL, Chabot B. SRSF10 Connects DNA Damage to the Alternative Splicing of Transcripts Encoding Apoptosis, Cell-Cycle Control, and DNA Repair Factors. Cell Reports. 17: 1990-2003. PMID 27851963 DOI: 10.1016/J.Celrep.2016.10.071 |
0.417 |
|
| 2016 |
Tian B, Manley JL. Alternative polyadenylation of mRNA precursors. Nature Reviews. Molecular Cell Biology. PMID 27677860 DOI: 10.1038/Nrm.2016.116 |
0.511 |
|
| 2016 |
Conlon EG, Lu L, Sharma A, Yamazaki T, Tang T, Shneider NA, Manley JL. The C9ORF72 GGGGCC expansion forms RNA G-quadruplex inclusions and sequesters hnRNP H to disrupt splicing in ALS patient brains. Elife. 5. PMID 27623008 DOI: 10.7554/Elife.17820 |
0.349 |
|
| 2016 |
Richard P, Manley JL. R loops and links to human disease. Journal of Molecular Biology. PMID 27600412 DOI: 10.1016/J.Jmb.2016.08.031 |
0.328 |
|
| 2016 |
Morales JC, Richard P, Patidar PL, Motea EA, Dang TT, Manley JL, Boothman DA. XRN2 Links Transcription Termination to DNA Damage and Replication Stress. Plos Genetics. 12: e1006107. PMID 27437695 DOI: 10.1371/Journal.Pgen.1006107 |
0.361 |
|
| 2016 |
Conlon EG, Lu L, Sharma A, Yamazaki T, Tang T, Shneider NA, Manley JL. Author response: The C9ORF72 GGGGCC expansion forms RNA G-quadruplex inclusions and sequesters hnRNP H to disrupt splicing in ALS brains Elife. DOI: 10.7554/Elife.17820.030 |
0.341 |
|
| 2015 |
Zhang J, Lieu YK, Ali AM, Penson A, Reggio KS, Rabadan R, Raza A, Mukherjee S, Manley JL. Disease-associated mutation in SRSF2 misregulates splicing by altering RNA-binding affinities. Proceedings of the National Academy of Sciences of the United States of America. PMID 26261309 DOI: 10.1073/Pnas.1514105112 |
0.455 |
|
| 2015 |
Coady TH, Manley JL. ALS mutations in TLS/FUS disrupt target gene expression. Genes & Development. 29: 1696-706. PMID 26251528 DOI: 10.1101/Gad.267286.115 |
0.357 |
|
| 2015 |
Pfister NT, Fomin V, Regunath K, Zhou JY, Zhou W, Silwal-Pandit L, Freed-Pastor WA, Laptenko O, Neo SP, Bargonetti J, Hoque M, Tian B, Gunaratne J, Engebraaten O, Manley JL, et al. Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells. Genes & Development. 29: 1298-315. PMID 26080815 DOI: 10.1101/Gad.263202.115 |
0.363 |
|
| 2015 |
Drisaldi B, Colnaghi L, Fioriti L, Rao N, Myers C, Snyder AM, Metzger DJ, Tarasoff J, Konstantinov E, Fraser PE, Manley JL, Kandel ER. SUMOylation Is an Inhibitory Constraint that Regulates the Prion-like Aggregation and Activity of CPEB3. Cell Reports. 11: 1694-702. PMID 26074071 DOI: 10.1016/J.Celrep.2015.04.061 |
0.367 |
|
| 2015 |
Shi Y, Manley JL. The end of the message: multiple protein-RNA interactions define the mRNA polyadenylation site. Genes & Development. 29: 889-97. PMID 25934501 DOI: 10.1101/Gad.261974.115 |
0.504 |
|
| 2015 |
Li W, You B, Hoque M, Zheng D, Luo W, Ji Z, Park JY, Gunderson SI, Kalsotra A, Manley JL, Tian B. Systematic profiling of poly(A)+ transcripts modulated by core 3' end processing and splicing factors reveals regulatory rules of alternative cleavage and polyadenylation. Plos Genetics. 11: e1005166. PMID 25906188 DOI: 10.1371/Journal.Pgen.1005166 |
0.437 |
|
| 2015 |
Manley JL. A journey to the end of the message. Rna (New York, N.Y.). 21: 538-40. PMID 25780128 DOI: 10.1261/Rna.050724.115 |
0.498 |
|
| 2015 |
Ng CH, Akhter A, Yurko N, Burgener JM, Rosonina E, Manley JL. Sumoylation controls the timing of Tup1-mediated transcriptional deactivation. Nature Communications. 6: 6610. PMID 25766875 DOI: 10.1038/Ncomms7610 |
0.451 |
|
| 2014 |
Di Giammartino DC, Li W, Ogami K, Yashinskie JJ, Hoque M, Tian B, Manley JL. RBBP6 isoforms regulate the human polyadenylation machinery and modulate expression of mRNAs with AU-rich 3' UTRs. Genes & Development. 28: 2248-60. PMID 25319826 DOI: 10.1101/Gad.245787.114 |
0.508 |
|
| 2014 |
Chan SL, Huppertz I, Yao C, Weng L, Moresco JJ, Yates JR, Ule J, Manley JL, Shi Y. CPSF30 and Wdr33 directly bind to AAUAAA in mammalian mRNA 3' processing. Genes & Development. 28: 2370-80. PMID 25301780 DOI: 10.1101/Gad.250993.114 |
0.488 |
|
| 2014 |
Di Giammartino DC, Manley JL. New links between mRNA polyadenylation and diverse nuclear pathways. Molecules and Cells. 37: 644-9. PMID 25081038 DOI: 10.14348/Molcells.2014.0177 |
0.479 |
|
| 2014 |
Rosonina E, Yurko N, Li W, Hoque M, Tian B, Manley JL. Threonine-4 of the budding yeast RNAP II CTD couples transcription with Htz1-mediated chromatin remodeling. Proceedings of the National Academy of Sciences of the United States of America. 111: 11924-31. PMID 25071213 DOI: 10.1073/Pnas.1412802111 |
0.466 |
|
| 2014 |
Richard P, Manley JL. SETX sumoylation: A link between DNA damage and RNA surveillance disrupted in AOA2. Rare Diseases (Austin, Tex.). 2: e27744. PMID 25054092 DOI: 10.4161/rdis.27744 |
0.352 |
|
| 2014 |
Hsin JP, Li W, Hoque M, Tian B, Manley JL. RNAP II CTD tyrosine 1 performs diverse functions in vertebrate cells. Elife. 3: e02112. PMID 24842995 DOI: 10.7554/Elife.02112 |
0.441 |
|
| 2014 |
Hsin JP, Xiang K, Manley JL. Function and control of RNA polymerase II C-terminal domain phosphorylation in vertebrate transcription and RNA processing. Molecular and Cellular Biology. 34: 2488-98. PMID 24752900 DOI: 10.1128/Mcb.00181-14 |
0.464 |
|
| 2014 |
Xiang K, Tong L, Manley JL. Delineating the structural blueprint of the pre-mRNA 3'-end processing machinery. Molecular and Cellular Biology. 34: 1894-910. PMID 24591651 DOI: 10.1128/Mcb.00084-14 |
0.403 |
|
| 2014 |
Nagaike T, Manley JL. In vitro analysis of transcriptional activators and polyadenylation. Methods in Molecular Biology (Clifton, N.J.). 1125: 65-74. PMID 24590780 DOI: 10.1007/978-1-62703-971-0_6 |
0.447 |
|
| 2014 |
Morales JC, Richard P, Rommel A, Fattah FJ, Motea EA, Patidar PL, Xiao L, Leskov K, Wu SY, Hittelman WN, Chiang CM, Manley JL, Boothman DA. Kub5-Hera, the human Rtt103 homolog, plays dual functional roles in transcription termination and DNA repair. Nucleic Acids Research. 42: 4996-5006. PMID 24589584 DOI: 10.1093/Nar/Gku160 |
0.349 |
|
| 2014 |
Zhou X, Wu W, Li H, Cheng Y, Wei N, Zong J, Feng X, Xie Z, Chen D, Manley JL, Wang H, Feng Y. Transcriptome analysis of alternative splicing events regulated by SRSF10 reveals position-dependent splicing modulation. Nucleic Acids Research. 42: 4019-30. PMID 24442672 DOI: 10.1093/nar/gkt1387 |
0.317 |
|
| 2013 |
Zhang J, Manley JL. Misregulation of pre-mRNA alternative splicing in cancer. Cancer Discovery. 3: 1228-37. PMID 24145039 DOI: 10.1158/2159-8290.Cd-13-0253 |
0.427 |
|
| 2013 |
Richard P, Feng S, Manley JL. A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage. Genes & Development. 27: 2227-32. PMID 24105744 DOI: 10.1101/Gad.224923.113 |
0.395 |
|
| 2013 |
Richard P, Manley JL. How bidirectional becomes unidirectional. Nature Structural & Molecular Biology. 20: 1022-4. PMID 24008561 DOI: 10.1038/Nsmb.2657 |
0.48 |
|
| 2013 |
Vi SL, Trost G, Lange P, Czesnick H, Rao N, Lieber D, Laux T, Gray WM, Manley JL, Groth D, Kappel C, Lenhard M. Target specificity among canonical nuclear poly(A) polymerases in plants modulates organ growth and pathogen response. Proceedings of the National Academy of Sciences of the United States of America. 110: 13994-9. PMID 23918356 DOI: 10.1073/Pnas.1303967110 |
0.41 |
|
| 2013 |
Li H, Wang Z, Zhou X, Cheng Y, Xie Z, Manley JL, Feng Y. Far upstream element-binding protein 1 and RNA secondary structure both mediate second-step splicing repression. Proceedings of the National Academy of Sciences of the United States of America. 110: E2687-95. PMID 23818605 DOI: 10.1073/Pnas.1310607110 |
0.508 |
|
| 2013 |
Tian B, Manley JL. Alternative cleavage and polyadenylation: the long and short of it. Trends in Biochemical Sciences. 38: 312-20. PMID 23632313 DOI: 10.1016/J.Tibs.2013.03.005 |
0.409 |
|
| 2013 |
Manley JL. SELEX to identify protein-binding sites on RNA. Cold Spring Harbor Protocols. 2013: 156-63. PMID 23378656 DOI: 10.1101/Pdb.Prot072934 |
0.429 |
|
| 2013 |
Di Giammartino DC, Shi Y, Manley JL. PARP1 represses PAP and inhibits polyadenylation during heat shock. Molecular Cell. 49: 7-17. PMID 23219533 DOI: 10.1016/J.Molcel.2012.11.005 |
0.461 |
|
| 2013 |
Zhang J, Neupane R, Canoll P, Lieu Y, Mukherjee S, Rabadan R, Raza A, Manley JL. Abstract IA6: Misregulation of pre-mRNA splicing in cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Fbcr13-Ia6 |
0.456 |
|
| 2012 |
Biderman L, Manley JL, Prives C. Mdm2 and MdmX as Regulators of Gene Expression. Genes & Cancer. 3: 264-73. PMID 23150759 DOI: 10.1177/1947601912455331 |
0.425 |
|
| 2012 |
Xiang K, Manley JL, Tong L. An unexpected binding mode for a Pol II CTD peptide phosphorylated at Ser7 in the active site of the CTD phosphatase Ssu72. Genes & Development. 26: 2265-70. PMID 23070812 DOI: 10.1101/Gad.198853.112 |
0.321 |
|
| 2012 |
Hsin JP, Manley JL. The RNA polymerase II CTD coordinates transcription and RNA processing. Genes & Development. 26: 2119-37. PMID 23028141 DOI: 10.1101/Gad.200303.112 |
0.511 |
|
| 2012 |
Tan AY, Manley JL. TLS/FUS: a protein in cancer and ALS. Cell Cycle (Georgetown, Tex.). 11: 3349-50. PMID 22918236 DOI: 10.4161/Cc.21875 |
0.571 |
|
| 2012 |
Xiang K, Manley JL, Tong L. The yeast regulator of transcription protein Rtr1 lacks an active site and phosphatase activity. Nature Communications. 3: 946. PMID 22781759 DOI: 10.1038/Ncomms1947 |
0.448 |
|
| 2012 |
Tan AY, Riley TR, Coady T, Bussemaker HJ, Manley JL. TLS/FUS (translocated in liposarcoma/fused in sarcoma) regulates target gene transcription via single-stranded DNA response elements. Proceedings of the National Academy of Sciences of the United States of America. 109: 6030-5. PMID 22460799 DOI: 10.1073/Pnas.1203028109 |
0.68 |
|
| 2012 |
Rosonina E, Duncan SM, Manley JL. Sumoylation of transcription factor Gcn4 facilitates its Srb10-mediated clearance from promoters in yeast. Genes & Development. 26: 350-5. PMID 22345516 DOI: 10.1101/Gad.184689.111 |
0.493 |
|
| 2012 |
Chen M, David CJ, Manley JL. Concentration-dependent control of pyruvate kinase M mutually exclusive splicing by hnRNP proteins. Nature Structural & Molecular Biology. 19: 346-54. PMID 22307054 DOI: 10.1038/Nsmb.2219 |
0.431 |
|
| 2012 |
Biderman L, Poyurovsky MV, Assia Y, Manley JL, Prives C. MdmX is required for p53 interaction with and full induction of the Mdm2 promoter after cellular stress. Molecular and Cellular Biology. 32: 1214-25. PMID 22290440 DOI: 10.1128/Mcb.06150-11 |
0.332 |
|
| 2012 |
Kanehiro Y, Todo K, Negishi M, Fukuoka J, Gan W, Hikasa T, Kaga Y, Takemoto M, Magari M, Li X, Manley JL, Ohmori H, Kanayama N. Activation-induced cytidine deaminase (AID)-dependent somatic hypermutation requires a splice isoform of the serine/arginine-rich (SR) protein SRSF1. Proceedings of the National Academy of Sciences of the United States of America. 109: 1216-21. PMID 22232677 DOI: 10.1073/Pnas.1120368109 |
0.436 |
|
| 2011 |
David CJ, Manley JL. The RNA polymerase C-terminal domain: a new role in spliceosome assembly. Transcription. 2: 221-5. PMID 22231118 DOI: 10.4161/trns.2.5.17272 |
0.397 |
|
| 2011 |
Hsin JP, Sheth A, Manley JL. RNAP II CTD phosphorylated on threonine-4 is required for histone mRNA 3' end processing. Science (New York, N.Y.). 334: 683-6. PMID 22053051 DOI: 10.1126/Science.1206034 |
0.465 |
|
| 2011 |
Gan W, Guan Z, Liu J, Gui T, Shen K, Manley JL, Li X. R-loop-mediated genomic instability is caused by impairment of replication fork progression. Genes & Development. 25: 2041-56. PMID 21979917 DOI: 10.1101/Gad.17010011 |
0.308 |
|
| 2011 |
Nagaike T, Manley JL. Transcriptional activators enhance polyadenylation of mRNA precursors. Rna Biology. 8: 964-7. PMID 21941122 DOI: 10.4161/Rna.8.6.17210 |
0.455 |
|
| 2011 |
Di Giammartino DC, Nishida K, Manley JL. Mechanisms and consequences of alternative polyadenylation. Molecular Cell. 43: 853-66. PMID 21925375 DOI: 10.1016/J.Molcel.2011.08.017 |
0.438 |
|
| 2011 |
David CJ, Boyne AR, Millhouse SR, Manley JL. The RNA polymerase II C-terminal domain promotes splicing activation through recruitment of a U2AF65-Prp19 complex. Genes & Development. 25: 972-83. PMID 21536736 DOI: 10.1101/Gad.2038011 |
0.504 |
|
| 2011 |
Nagaike T, Logan C, Hotta I, Rozenblatt-Rosen O, Meyerson M, Manley JL. Transcriptional activators enhance polyadenylation of mRNA precursors. Molecular Cell. 41: 409-18. PMID 21329879 DOI: 10.1016/J.Molcel.2011.01.022 |
0.511 |
|
| 2011 |
Chang JH, Xiang S, Xiang K, Manley JL, Tong L. Structural and biochemical studies of the 5'→3' exoribonuclease Xrn1. Nature Structural & Molecular Biology. 18: 270-6. PMID 21297639 DOI: 10.1038/Nsmb.1984 |
0.396 |
|
| 2011 |
Bai Y, Srivastava SK, Chang JH, Manley JL, Tong L. Structural basis for dimerization and activity of human PAPD1, a noncanonical poly(A) polymerase. Molecular Cell. 41: 311-20. PMID 21292163 DOI: 10.1016/J.Molcel.2011.01.013 |
0.407 |
|
| 2011 |
Shi Y, Nishida K, Campigli Di Giammartino D, Manley JL. Heat shock-induced SRSF10 dephosphorylation displays thermotolerance mediated by Hsp27. Molecular and Cellular Biology. 31: 458-65. PMID 21135127 DOI: 10.1128/Mcb.01123-10 |
0.746 |
|
| 2010 |
David CJ, Manley JL. Alternative pre-mRNA splicing regulation in cancer: pathways and programs unhinged. Genes & Development. 24: 2343-64. PMID 21041405 DOI: 10.1101/Gad.1973010 |
0.403 |
|
| 2010 |
Chen M, Zhang J, Manley JL. Turning on a fuel switch of cancer: hnRNP proteins regulate alternative splicing of pyruvate kinase mRNA. Cancer Research. 70: 8977-80. PMID 20978194 DOI: 10.1158/0008-5472.Can-10-2513 |
0.353 |
|
| 2010 |
Xiang K, Nagaike T, Xiang S, Kilic T, Beh MM, Manley JL, Tong L. Crystal structure of the human symplekin-Ssu72-CTD phosphopeptide complex. Nature. 467: 729-33. PMID 20861839 DOI: 10.1038/Nature09391 |
0.464 |
|
| 2010 |
GarcÃa A, Rosonina E, Manley JL, Calvo O. Sub1 globally regulates RNA polymerase II C-terminal domain phosphorylation. Molecular and Cellular Biology. 30: 5180-93. PMID 20823273 DOI: 10.1128/Mcb.00819-10 |
0.444 |
|
| 2010 |
Mutsuddi M, Mukherjee A, Shen B, Manley JL, Nambu JR. Drosophila Pelle phosphorylates Dichaete protein and influences its subcellular distribution in developing oocytes. The International Journal of Developmental Biology. 54: 1309-15. PMID 20563992 DOI: 10.1387/Ijdb.092991Mm |
0.493 |
|
| 2010 |
Manley JL, Krainer AR. A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins). Genes & Development. 24: 1073-4. PMID 20516191 DOI: 10.1101/Gad.1934910 |
0.463 |
|
| 2010 |
Chen M, David CJ, Manley JL. Tumor metabolism: hnRNP proteins get in on the act. Cell Cycle (Georgetown, Tex.). 9: 1863-4. PMID 20505328 DOI: 10.4161/Cc.9.10.11675 |
0.368 |
|
| 2010 |
Rosonina E, Duncan SM, Manley JL. SUMO functions in constitutive transcription and during activation of inducible genes in yeast. Genes & Development. 24: 1242-52. PMID 20504900 DOI: 10.1101/Gad.1917910 |
0.451 |
|
| 2010 |
Pedrotti S, Bielli P, Paronetto MP, Ciccosanti F, Fimia GM, Stamm S, Manley JL, Sette C. The splicing regulator Sam68 binds to a novel exonic splicing silencer and functions in SMN2 alternative splicing in spinal muscular atrophy. The Embo Journal. 29: 1235-47. PMID 20186123 DOI: 10.1038/Emboj.2010.19 |
0.44 |
|
| 2010 |
Rosonina E, Manley JL. Alternative polyadenylation blooms. Developmental Cell. 18: 172-4. PMID 20159589 DOI: 10.1016/J.Devcel.2010.02.001 |
0.338 |
|
| 2010 |
David CJ, Chen M, Assanah M, Canoll P, Manley JL. HnRNP proteins controlled by c-Myc deregulate pyruvate kinase mRNA splicing in cancer. Nature. 463: 364-8. PMID 20010808 DOI: 10.1038/Nature08697 |
0.416 |
|
| 2010 |
Tan AY, Manley JL. TLS inhibits RNA polymerase III transcription. Molecular and Cellular Biology. 30: 186-96. PMID 19841068 DOI: 10.1128/Mcb.00884-09 |
0.726 |
|
| 2010 |
Chen LS, Du-Cuny L, Vethantham V, Hawke DH, Manley JL, Zhang S, Gandhi V. Chain termination and inhibition of mammalian poly(A) polymerase by modified ATP analogues. Biochemical Pharmacology. 79: 669-77. PMID 19814999 DOI: 10.1016/J.Bcp.2009.09.028 |
0.405 |
|
| 2010 |
Manley J. 635 Transcription and RNA Processing: links to cancer European Journal of Cancer Supplements. 8: 161. DOI: 10.1016/S1359-6349(10)71435-X |
0.308 |
|
| 2009 |
Tan AY, Manley JL. The TET family of proteins: functions and roles in disease. Journal of Molecular Cell Biology. 1: 82-92. PMID 19783543 DOI: 10.1093/Jmcb/Mjp025 |
0.708 |
|
| 2009 |
Chen M, Manley JL. Mechanisms of alternative splicing regulation: insights from molecular and genomics approaches. Nature Reviews. Molecular Cell Biology. 10: 741-54. PMID 19773805 DOI: 10.1038/Nrm2777 |
0.44 |
|
| 2009 |
Beckerman R, Donner AJ, Mattia M, Peart MJ, Manley JL, Espinosa JM, Prives C. A role for Chk1 in blocking transcriptional elongation of p21 RNA during the S-phase checkpoint. Genes & Development. 23: 1364-77. PMID 19487575 DOI: 10.1101/Gad.1795709 |
0.423 |
|
| 2009 |
Richard P, Manley JL. Transcription termination by nuclear RNA polymerases. Genes & Development. 23: 1247-69. PMID 19487567 DOI: 10.1101/Gad.1792809 |
0.499 |
|
| 2009 |
Wachtel C, Manley JL. Splicing of mRNA precursors: the role of RNAs and proteins in catalysis. Molecular Biosystems. 5: 311-6. PMID 19396366 DOI: 10.1039/B820828J |
0.494 |
|
| 2009 |
Feng Y, Valley MT, Lazar J, Yang AL, Bronson RT, Firestein S, Coetzee WA, Manley JL. SRp38 regulates alternative splicing and is required for Ca(2+) handling in the embryonic heart. Developmental Cell. 16: 528-38. PMID 19386262 DOI: 10.1016/J.Devcel.2009.02.009 |
0.354 |
|
| 2009 |
Loomis RJ, Naoe Y, Parker JB, Savic V, Bozovsky MR, Macfarlan T, Manley JL, Chakravarti D. Chromatin binding of SRp20 and ASF/SF2 and dissociation from mitotic chromosomes is modulated by histone H3 serine 10 phosphorylation. Molecular Cell. 33: 450-61. PMID 19250906 DOI: 10.1016/J.Molcel.2009.02.003 |
0.316 |
|
| 2009 |
Shi Y, Di Giammartino DC, Taylor D, Sarkeshik A, Rice WJ, Yates JR, Frank J, Manley JL. Molecular architecture of the human pre-mRNA 3' processing complex. Molecular Cell. 33: 365-76. PMID 19217410 DOI: 10.1016/J.Molcel.2008.12.028 |
0.394 |
|
| 2009 |
Rosonina E, Willis IM, Manley JL. Sub1 functions in osmoregulation and in transcription by both RNA polymerases II and III. Molecular and Cellular Biology. 29: 2308-21. PMID 19204085 DOI: 10.1128/Mcb.01841-08 |
0.423 |
|
| 2009 |
Xiang S, Cooper-Morgan A, Jiao X, Kiledjian M, Manley JL, Tong L. Structure and function of the 5'-->3' exoribonuclease Rat1 and its activating partner Rai1. Nature. 458: 784-8. PMID 19194460 DOI: 10.1038/Nature07731 |
0.399 |
|
| 2009 |
Rozenblatt-Rosen O, Nagaike T, Francis JM, Kaneko S, Glatt KA, Hughes CM, LaFramboise T, Manley JL, Meyerson M. The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors. Proceedings of the National Academy of Sciences of the United States of America. 106: 755-60. PMID 19136632 DOI: 10.1073/Pnas.0812023106 |
0.62 |
|
| 2009 |
Valadkhan S, Manley JL. The use of simple model systems to study spliceosomal catalysis. Rna (New York, N.Y.). 15: 4-7. PMID 19029305 DOI: 10.1261/Rna.1425809 |
0.687 |
|
| 2008 |
Feng Y, Chen M, Manley JL. Phosphorylation switches the general splicing repressor SRp38 to a sequence-specific activator. Nature Structural & Molecular Biology. 15: 1040-8. PMID 18794844 DOI: 10.1038/Nsmb.1485 |
0.451 |
|
| 2008 |
Vethantham V, Rao N, Manley JL. Sumoylation regulates multiple aspects of mammalian poly(A) polymerase function. Genes & Development. 22: 499-511. PMID 18281463 DOI: 10.1101/Gad.1628208 |
0.437 |
|
| 2008 |
Mirkin N, Fonseca D, Mohammed S, Cevher MA, Manley JL, Kleiman FE. The 3' processing factor CstF functions in the DNA repair response. Nucleic Acids Research. 36: 1792-804. PMID 18252771 DOI: 10.1093/Nar/Gkn005 |
0.786 |
|
| 2008 |
David CJ, Manley JL. The search for alternative splicing regulators: new approaches offer a path to a splicing code. Genes & Development. 22: 279-85. PMID 18245441 DOI: 10.1101/Gad.1643108 |
0.396 |
|
| 2008 |
Bush SD, Richard P, Manley JL. Variations in intracellular levels of TATA binding protein can affect specific genes by different mechanisms. Molecular and Cellular Biology. 28: 83-92. PMID 17954564 DOI: 10.1128/Mcb.00809-07 |
0.433 |
|
| 2007 |
Sims RJ, Millhouse S, Chen CF, Lewis BA, Erdjument-Bromage H, Tempst P, Manley JL, Reinberg D. Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing. Molecular Cell. 28: 665-76. PMID 18042460 DOI: 10.1016/J.Molcel.2007.11.010 |
0.428 |
|
| 2007 |
Xu YX, Manley JL. Pin1 modulates RNA polymerase II activity during the transcription cycle. Genes & Development. 21: 2950-62. PMID 18006688 DOI: 10.1101/Gad.1592807 |
0.478 |
|
| 2007 |
Xu YX, Manley JL. New insights into mitotic chromosome condensation: a role for the prolyl isomerase Pin1. Cell Cycle (Georgetown, Tex.). 6: 2896-901. PMID 17993783 DOI: 10.4161/Cc.6.23.4977 |
0.307 |
|
| 2007 |
Kaneko S, Chu C, Shatkin AJ, Manley JL. Human capping enzyme promotes formation of transcriptional R loops in vitro. Proceedings of the National Academy of Sciences of the United States of America. 104: 17620-5. PMID 17978174 DOI: 10.1073/Pnas.0708866104 |
0.679 |
|
| 2007 |
Li X, Niu T, Manley JL. The RNA binding protein RNPS1 alleviates ASF/SF2 depletion-induced genomic instability. Rna (New York, N.Y.). 13: 2108-15. PMID 17959926 DOI: 10.1261/Rna.734407 |
0.492 |
|
| 2007 |
Valadkhan S, Mohammadi A, Wachtel C, Manley JL. Protein-free spliceosomal snRNAs catalyze a reaction that resembles the first step of splicing. Rna (New York, N.Y.). 13: 2300-11. PMID 17940139 DOI: 10.1261/Rna.626207 |
0.728 |
|
| 2007 |
Shi Y, Manley JL. A complex signaling pathway regulates SRp38 phosphorylation and pre-mRNA splicing in response to heat shock. Molecular Cell. 28: 79-90. PMID 17936706 DOI: 10.1016/J.Molcel.2007.08.028 |
0.436 |
|
| 2007 |
Vethantham V, Rao N, Manley JL. Sumoylation modulates the assembly and activity of the pre-mRNA 3' processing complex. Molecular and Cellular Biology. 27: 8848-58. PMID 17923699 DOI: 10.1128/Mcb.01186-07 |
0.439 |
|
| 2007 |
Kashima T, Rao N, David CJ, Manley JL. hnRNP A1 functions with specificity in repression of SMN2 exon 7 splicing. Human Molecular Genetics. 16: 3149-59. PMID 17884807 DOI: 10.1093/Hmg/Ddm276 |
0.385 |
|
| 2007 |
Kaneko S, Rozenblatt-Rosen O, Meyerson M, Manley JL. The multifunctional protein p54nrb/PSF recruits the exonuclease XRN2 to facilitate pre-mRNA 3' processing and transcription termination. Genes & Development. 21: 1779-89. PMID 17639083 DOI: 10.1101/Gad.1565207 |
0.669 |
|
| 2007 |
Lazarev D, Manley JL. Concurrent splicing and transcription are not sufficient to enhance splicing efficiency. Rna (New York, N.Y.). 13: 1546-57. PMID 17630325 DOI: 10.1261/Rna.595907 |
0.488 |
|
| 2007 |
Ali GS, Palusa SG, Golovkin M, Prasad J, Manley JL, Reddy AS. Regulation of plant developmental processes by a novel splicing factor. Plos One. 2: e471. PMID 17534421 DOI: 10.1371/Journal.Pone.0000471 |
0.416 |
|
| 2007 |
Xu YX, Manley JL. The prolyl isomerase Pin1 functions in mitotic chromosome condensation. Molecular Cell. 26: 287-300. PMID 17466629 DOI: 10.1016/J.Molcel.2007.03.020 |
0.304 |
|
| 2007 |
Bai Y, Auperin TC, Chou CY, Chang GG, Manley JL, Tong L. Crystal structure of murine CstF-77: dimeric association and implications for polyadenylation of mRNA precursors. Molecular Cell. 25: 863-75. PMID 17386263 DOI: 10.1016/J.Molcel.2007.01.034 |
0.363 |
|
| 2007 |
Kashima T, Rao N, Manley JL. An intronic element contributes to splicing repression in spinal muscular atrophy. Proceedings of the National Academy of Sciences of the United States of America. 104: 3426-31. PMID 17307868 DOI: 10.1073/Pnas.0700343104 |
0.353 |
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| 2006 |
Bush S, Manley JL. Transcription and RNA processing factors play complex roles in DT40 cells. Sub-Cellular Biochemistry. 40: 207-23. PMID 17623907 DOI: 10.1007/978-1-4020-4896-8_12 |
0.494 |
|
| 2006 |
Mandel CR, Kaneko S, Zhang H, Gebauer D, Vethantham V, Manley JL, Tong L. Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease. Nature. 444: 953-6. PMID 17128255 DOI: 10.1038/Nature05363 |
0.626 |
|
| 2006 |
Shi Y, Reddy B, Manley JL. PP1/PP2A phosphatases are required for the second step of Pre-mRNA splicing and target specific snRNP proteins. Molecular Cell. 23: 819-29. PMID 16973434 DOI: 10.1016/J.Molcel.2006.07.022 |
0.427 |
|
| 2006 |
Li X, Manley JL. Cotranscriptional processes and their influence on genome stability. Genes & Development. 20: 1838-47. PMID 16847344 DOI: 10.1101/Gad.1438306 |
0.394 |
|
| 2006 |
Li X, Manley JL. Alternative splicing and control of apoptotic DNA fragmentation. Cell Cycle (Georgetown, Tex.). 5: 1286-8. PMID 16760667 DOI: 10.4161/Cc.5.12.2832 |
0.45 |
|
| 2006 |
Rosonina E, Kaneko S, Manley JL. Terminating the transcript: breaking up is hard to do. Genes & Development. 20: 1050-6. PMID 16651651 DOI: 10.1101/Gad.1431606 |
0.595 |
|
| 2006 |
Marin-Vinader L, Shin C, Onnekink C, Manley JL, Lubsen NH. Hsp27 enhances recovery of splicing as well as rephosphorylation of SRp38 after heat shock. Molecular Biology of the Cell. 17: 886-94. PMID 16339078 DOI: 10.1091/Mbc.E05-07-0596 |
0.537 |
|
| 2005 |
Li X, Manley JL. New talents for an old acquaintance: the SR protein splicing factor ASF/SF2 functions in the maintenance of genome stability. Cell Cycle (Georgetown, Tex.). 4: 1706-8. PMID 16294036 DOI: 10.4161/Cc.4.12.2210 |
0.384 |
|
| 2005 |
Li X, Wang J, Manley JL. Loss of splicing factor ASF/SF2 induces G2 cell cycle arrest and apoptosis, but inhibits internucleosomal DNA fragmentation. Genes & Development. 19: 2705-14. PMID 16260492 DOI: 10.1101/Gad.1359305 |
0.384 |
|
| 2005 |
Rosonina E, Manley JL. From transcription to mRNA: PAF provides a new path. Molecular Cell. 20: 167-8. PMID 16246718 DOI: 10.1016/J.Molcel.2005.10.004 |
0.48 |
|
| 2005 |
Kaneko S, Manley JL. The mammalian RNA polymerase II C-terminal domain interacts with RNA to suppress transcription-coupled 3' end formation. Molecular Cell. 20: 91-103. PMID 16209948 DOI: 10.1016/J.Molcel.2005.08.033 |
0.686 |
|
| 2005 |
Shin C, Kleiman FE, Manley JL. Multiple properties of the splicing repressor SRp38 distinguish it from typical SR proteins. Molecular and Cellular Biology. 25: 8334-43. PMID 16135820 DOI: 10.1128/Mcb.25.18.8334-8343.2005 |
0.785 |
|
| 2005 |
Li X, Manley JL. Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability. Cell. 122: 365-78. PMID 16096057 DOI: 10.1016/J.Cell.2005.06.008 |
0.458 |
|
| 2005 |
Kleiman FE, Wu-Baer F, Fonseca D, Kaneko S, Baer R, Manley JL. BRCA1/BARD1 inhibition of mRNA 3' processing involves targeted degradation of RNA polymerase II. Genes & Development. 19: 1227-37. PMID 15905410 DOI: 10.1101/Gad.1309505 |
0.805 |
|
| 2005 |
Calvo O, Manley JL. The transcriptional coactivator PC4/Sub1 has multiple functions in RNA polymerase II transcription. The Embo Journal. 24: 1009-20. PMID 15692559 DOI: 10.1038/Sj.Emboj.7600575 |
0.479 |
|
| 2005 |
Xu X, Yang D, Ding JH, Wang W, Chu PH, Dalton ND, Wang HY, Bermingham JR, Ye Z, Liu F, Rosenfeld MG, Manley JL, Ross J, Chen J, Xiao RP, et al. ASF/SF2-regulated CaMKIIdelta alternative splicing temporally reprograms excitation-contraction coupling in cardiac muscle. Cell. 120: 59-72. PMID 15652482 DOI: 10.1016/J.Cell.2004.11.036 |
0.331 |
|
| 2005 |
Millhouse S, Manley JL. The C-terminal domain of RNA polymerase II functions as a phosphorylation-dependent splicing activator in a heterologous protein. Molecular and Cellular Biology. 25: 533-44. PMID 15632056 DOI: 10.1128/Mcb.25.2.533-544.2005 |
0.492 |
|
| 2004 |
Barnard DC, Ryan K, Manley JL, Richter JD. Symplekin and xGLD-2 are required for CPEB-mediated cytoplasmic polyadenylation. Cell. 119: 641-51. PMID 15550246 DOI: 10.1016/J.Cell.2004.10.029 |
0.621 |
|
| 2004 |
Shin C, Manley JL. Cell signalling and the control of pre-mRNA splicing. Nature Reviews. Molecular Cell Biology. 5: 727-38. PMID 15340380 DOI: 10.1038/Nrm1467 |
0.61 |
|
| 2004 |
Ryan K, Calvo O, Manley JL. Evidence that polyadenylation factor CPSF-73 is the mRNA 3' processing endonuclease. Rna (New York, N.Y.). 10: 565-73. PMID 15037765 DOI: 10.1261/Rna.5214404 |
0.567 |
|
| 2004 |
Shin C, Feng Y, Manley JL. Dephosphorylated SRp38 acts as a splicing repressor in response to heat shock. Nature. 427: 553-8. PMID 14765198 DOI: 10.1038/Nature02288 |
0.615 |
|
| 2004 |
Xu YX, Manley JL. Pinning down transcription: regulation of RNA polymerase II activity during the cell cycle. Cell Cycle (Georgetown, Tex.). 3: 432-5. PMID 14739776 DOI: 10.4161/Cc.3.4.769 |
0.47 |
|
| 2003 |
Xu YX, Hirose Y, Zhou XZ, Lu KP, Manley JL. Pin1 modulates the structure and function of human RNA polymerase II. Genes & Development. 17: 2765-76. PMID 14600023 DOI: 10.1101/Gad.1135503 |
0.494 |
|
| 2003 |
Poyurovsky MV, Jacq X, Ma C, Karni-Schmidt O, Parker PJ, Chalfie M, Manley JL, Prives C. Nucleotide binding by the Mdm2 RING domain facilitates Arf-independent Mdm2 nucleolar localization. Molecular Cell. 12: 875-87. PMID 14580339 DOI: 10.1016/S1097-2765(03)00400-3 |
0.342 |
|
| 2003 |
Chen Z, Manley JL. Core promoter elements and TAFs contribute to the diversity of transcriptional activation in vertebrates. Molecular and Cellular Biology. 23: 7350-62. PMID 14517303 DOI: 10.1128/Mcb.23.20.7350-7362.2003 |
0.524 |
|
| 2003 |
Chen Z, Manley JL. In vivo functional analysis of the histone 3-like TAF9 and a TAF9-related factor, TAF9L. The Journal of Biological Chemistry. 278: 35172-83. PMID 12837753 DOI: 10.1074/Jbc.M304241200 |
0.551 |
|
| 2003 |
Kashima T, Manley JL. A negative element in SMN2 exon 7 inhibits splicing in spinal muscular atrophy. Nature Genetics. 34: 460-3. PMID 12833158 DOI: 10.1038/Ng1207 |
0.448 |
|
| 2003 |
Valadkhan S, Manley JL. Characterization of the catalytic activity of U2 and U6 snRNAs. Rna (New York, N.Y.). 9: 892-904. PMID 12810922 DOI: 10.1261/Rna.5440303 |
0.717 |
|
| 2003 |
Calvo O, Manley JL. Strange bedfellows: polyadenylation factors at the promoter. Genes & Development. 17: 1321-7. PMID 12782649 DOI: 10.1101/Gad.1093603 |
0.487 |
|
| 2003 |
Prasad J, Manley JL. Regulation and substrate specificity of the SR protein kinase Clk/Sty. Molecular and Cellular Biology. 23: 4139-49. PMID 12773558 DOI: 10.1128/Mcb.23.12.4139-4149.2003 |
0.336 |
|
| 2003 |
Schwerk C, Prasad J, Degenhardt K, Erdjument-Bromage H, White E, Tempst P, Kidd VJ, Manley JL, Lahti JM, Reinberg D. ASAP, a novel protein complex involved in RNA processing and apoptosis. Molecular and Cellular Biology. 23: 2981-90. PMID 12665594 DOI: 10.1128/Mcb.23.8.2981-2990.2003 |
0.434 |
|
| 2003 |
Portal D, Lobo GS, Kadener S, Prasad J, Espinosa JM, Pereira CA, Tang Z, Lin RJ, Manley JL, Kornblihtt AR, Flawiá MM, Torres HN. Trypanosoma cruzi TcSRPK, the first protozoan member of the SRPK family, is biochemically and functionally conserved with metazoan SR protein-specific kinases. Molecular and Biochemical Parasitology. 127: 9-21. PMID 12615332 DOI: 10.1016/S0166-6851(02)00299-2 |
0.364 |
|
| 2003 |
Shin C, Manley JL. Role of Alternative Splicing During the Cell Cycle and Programmed Cell Death Handbook of Cell Signaling. 3: 331-334. DOI: 10.1016/B978-012124546-7/50682-3 |
0.451 |
|
| 2002 |
Shin C, Manley JL. The SR protein SRp38 represses splicing in M phase cells. Cell. 111: 407-17. PMID 12419250 DOI: 10.1016/S0092-8674(02)01038-3 |
0.639 |
|
| 2002 |
Manley JL. Nuclear coupling: RNA processing reaches back to transcription. Nature Structural Biology. 9: 790-1. PMID 12402032 DOI: 10.1038/Nsb1102-790 |
0.466 |
|
| 2002 |
Valadkhan S, Manley JL. Intrinsic metal binding by a spliceosomal RNA. Nature Structural Biology. 9: 498-9. PMID 12080335 DOI: 10.1038/Nsb0702-498 |
0.689 |
|
| 2002 |
Shen B, Manley JL. Pelle kinase is activated by autophosphorylation during Toll signaling in Drosophila. Development (Cambridge, England). 129: 1925-33. PMID 11934858 |
0.41 |
|
| 2002 |
Chen A, Kleiman FE, Manley JL, Ouchi T, Pan ZQ. Autoubiquitination of the BRCA1*BARD1 RING ubiquitin ligase. The Journal of Biological Chemistry. 277: 22085-92. PMID 11927591 DOI: 10.1074/Jbc.M201252200 |
0.712 |
|
| 2002 |
Lemaire R, Prasad J, Kashima T, Gustafson J, Manley JL, Lafyatis R. Stability of a PKCI-1-related mRNA is controlled by the splicing factor ASF/SF2: a novel function for SR proteins. Genes & Development. 16: 594-607. PMID 11877379 DOI: 10.1101/Gad.939502 |
0.423 |
|
| 2002 |
Ryan K, Murthy KG, Kaneko S, Manley JL. Requirements of the RNA polymerase II C-terminal domain for reconstituting pre-mRNA 3' cleavage. Molecular and Cellular Biology. 22: 1684-92. PMID 11865048 DOI: 10.1128/Mcb.22.6.1684-1692.2002 |
0.702 |
|
| 2002 |
Valadkhan S, Manley JL. Erratum: Intrinsic metal binding by a spliceosomal RNA Nature Structural & Molecular Biology. 9: 711-711. DOI: 10.1038/Nsb0902-711B |
0.673 |
|
| 2001 |
Luo C, Shen B, Manley JL, Zheng L. Tehao functions in the Toll pathway in Drosophila melanogaster: possible roles in development and innate immunity. Insect Molecular Biology. 10: 457-64. PMID 11881810 DOI: 10.1046/j.0962-1075.2001.00284.x |
0.477 |
|
| 2001 |
Prives C, Manley JL. Why is p53 acetylated? Cell. 107: 815-8. PMID 11779456 DOI: 10.1016/S0092-8674(01)00619-5 |
0.344 |
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| 2001 |
Valadkhan S, Manley JL. Splicing-related catalysis by protein-free snRNAs. Nature. 413: 701-7. PMID 11607023 DOI: 10.1038/35099500 |
0.744 |
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| 2001 |
Topalian SL, Kaneko S, Gonzales MI, Bond GL, Ward Y, Manley JL. Identification and functional characterization of neo-poly(A) polymerase, an RNA processing enzyme overexpressed in human tumors. Molecular and Cellular Biology. 21: 5614-23. PMID 11463842 DOI: 10.1128/Mcb.21.16.5614-5623.2001 |
0.639 |
|
| 2001 |
Shen B, Liu H, Skolnik EY, Manley JL. Physical and functional interactions between Drosophila TRAF2 and Pelle kinase contribute to Dorsal activation. Proceedings of the National Academy of Sciences of the United States of America. 98: 8596-601. PMID 11447260 DOI: 10.1073/Pnas.141235698 |
0.52 |
|
| 2001 |
Calvo O, Manley JL. Evolutionarily conserved interaction between CstF-64 and PC4 links transcription, polyadenylation, and termination. Molecular Cell. 7: 1013-23. PMID 11389848 DOI: 10.1016/S1097-2765(01)00236-2 |
0.471 |
|
| 2001 |
Um M, Yamauchi J, Kato S, Manley JL. Heterozygous disruption of the TATA-binding protein gene in DT40 cells causes reduced cdc25B phosphatase expression and delayed mitosis. Molecular and Cellular Biology. 21: 2435-48. PMID 11259592 DOI: 10.1128/Mcb.21.7.2435-2448.2001 |
0.646 |
|
| 2001 |
Kleiman FE, Manley JL. The BARD1-CstF-50 interaction links mRNA 3' end formation to DNA damage and tumor suppression. Cell. 104: 743-53. PMID 11257228 DOI: 10.1016/S0092-8674(01)00270-7 |
0.748 |
|
| 2000 |
Um M, Manley JL. The Drosophila TATA binding protein contains a strong but masked activation domain. Gene Expression. 9: 123-32. PMID 11243409 |
0.638 |
|
| 2000 |
Mendez R, Murthy KG, Ryan K, Manley JL, Richter JD. Phosphorylation of CPEB by Eg2 mediates the recruitment of CPSF into an active cytoplasmic polyadenylation complex. Molecular Cell. 6: 1253-9. PMID 11106762 DOI: 10.1016/S1097-2765(00)00121-0 |
0.584 |
|
| 2000 |
Xu Y, Tao X, Shen B, Horng T, Medzhitov R, Manley JL, Tong L. Structural basis for signal transduction by the Toll/interleukin-1 receptor domains. Nature. 408: 111-5. PMID 11081518 DOI: 10.1038/35040600 |
0.446 |
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| 2000 |
Shatkin AJ, Manley JL. The ends of the affair: capping and polyadenylation. Nature Structural Biology. 7: 838-42. PMID 11017188 DOI: 10.1038/79583 |
0.47 |
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| 2000 |
Bond GL, Prives C, Manley JL. Poly(A) polymerase phosphorylation is dependent on novel interactions with cyclins. Molecular and Cellular Biology. 20: 5310-20. PMID 10866687 DOI: 10.1128/Mcb.20.14.5310-5320.2000 |
0.33 |
|
| 2000 |
Chen Z, Manley JL. Robust mRNA transcription in chicken DT40 cells depleted of TAF(II)31 suggests both functional degeneracy and evolutionary divergence. Molecular and Cellular Biology. 20: 5064-76. PMID 10866663 DOI: 10.1128/Mcb.20.14.5064-5076.2000 |
0.533 |
|
| 2000 |
Hirose Y, Manley JL. RNA polymerase II and the integration of nuclear events. Genes & Development. 14: 1415-29. PMID 10859161 DOI: 10.1101/Gad.14.12.1415 |
0.401 |
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| 2000 |
Koffa MD, Graham SV, Takagaki Y, Manley JL, Clements JB. The human papillomavirus type 16 negative regulatory RNA element interacts with three proteins that act at different posttranscriptional levels. Proceedings of the National Academy of Sciences of the United States of America. 97: 4677-82. PMID 10781073 DOI: 10.1073/Pnas.070049097 |
0.438 |
|
| 2000 |
Valadkhan S, Manley JL. A tertiary interaction detected in a human U2-U6 snRNA complex assembled in vitro resembles a genetically proven interaction in yeast. Rna (New York, N.Y.). 6: 206-19. PMID 10688360 DOI: 10.1017/S1355838200992197 |
0.712 |
|
| 2000 |
Takagaki Y, Manley JL. Complex protein interactions within the human polyadenylation machinery identify a novel component. Molecular and Cellular Biology. 20: 1515-25. PMID 10669729 DOI: 10.1128/Mcb.20.5.1515-1525.2000 |
0.455 |
|
| 2000 |
Hatton LS, Eloranta JJ, Figueiredo LM, Takagaki Y, Manley JL, O'Hare K. The Drosophila homologue of the 64 kDa subunit of cleavage stimulation factor interacts with the 77 kDa subunit encoded by the suppressor of forked gene. Nucleic Acids Research. 28: 520-6. PMID 10606651 DOI: 10.1093/Nar/28.2.520 |
0.486 |
|
| 1999 |
Prasad J, Colwill K, Pawson T, Manley JL. The protein kinase Clk/Sty directly modulates SR protein activity: both hyper- and hypophosphorylation inhibit splicing. Molecular and Cellular Biology. 19: 6991-7000. PMID 10490636 DOI: 10.1128/Mcb.19.10.6991 |
0.42 |
|
| 1999 |
Kleiman FE, Manley JL. Functional interaction of BRCA1-associated BARD1 with polyadenylation factor CstF-50. Science (New York, N.Y.). 285: 1576-9. PMID 10477523 DOI: 10.1126/Science.285.5433.1576 |
0.794 |
|
| 1999 |
Tacke R, Manley JL. Determinants of SR protein specificity. Current Opinion in Cell Biology. 11: 358-62. PMID 10395560 DOI: 10.1016/S0955-0674(99)80050-7 |
0.381 |
|
| 1999 |
Hirose Y, Tacke R, Manley JL. Phosphorylated RNA polymerase II stimulates pre-mRNA splicing. Genes & Development. 13: 1234-9. PMID 10346811 DOI: 10.1101/Gad.13.10.1234 |
0.486 |
|
| 1999 |
Li C, Manley JL. Allosteric regulation of even-skipped repression activity by phosphorylation. Molecular Cell. 3: 77-86. PMID 10024881 DOI: 10.1016/S1097-2765(00)80176-8 |
0.38 |
|
| 1999 |
Tacke R, Manley JL. Functions of SR and Tra2 proteins in pre-mRNA splicing regulation. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 220: 59-63. PMID 9933499 DOI: 10.1046/J.1525-1373.1999.D01-10.X |
0.436 |
|
| 1998 |
Takagaki Y, Manley JL. Levels of polyadenylation factor CstF-64 control IgM heavy chain mRNA accumulation and other events associated with B cell differentiation. Molecular Cell. 2: 761-71. PMID 9885564 DOI: 10.1016/S1097-2765(00)80291-9 |
0.359 |
|
| 1998 |
Shen B, Manley JL. Phosphorylation modulates direct interactions between the Toll receptor, Pelle kinase and Tube. Development (Cambridge, England). 125: 4719-28. PMID 9806920 |
0.475 |
|
| 1998 |
Xiao SH, Manley JL. Phosphorylation-dephosphorylation differentially affects activities of splicing factor ASF/SF2. The Embo Journal. 17: 6359-67. PMID 9799243 DOI: 10.1093/Emboj/17.21.6359 |
0.411 |
|
| 1998 |
Hirose Y, Manley JL. RNA polymerase II is an essential mRNA polyadenylation factor. Nature. 395: 93-6. PMID 9738505 DOI: 10.1038/25786 |
0.504 |
|
| 1998 |
Moreira A, Takagaki Y, Brackenridge S, Wollerton M, Manley JL, Proudfoot NJ. The upstream sequence element of the C2 complement poly(A) signal activates mRNA 3' end formation by two distinct mechanisms. Genes & Development. 12: 2522-34. PMID 9716405 DOI: 10.1101/Gad.12.16.2522 |
0.387 |
|
| 1998 |
Zhao W, Manley JL. Deregulation of poly(A) polymerase interferes with cell growth. Molecular and Cellular Biology. 18: 5010-20. PMID 9710585 DOI: 10.1128/Mcb.18.9.5010 |
0.331 |
|
| 1998 |
Wang J, Xiao SH, Manley JL. Genetic analysis of the SR protein ASF/SF2: interchangeability of RS domains and negative control of splicing. Genes & Development. 12: 2222-33. PMID 9679066 DOI: 10.1101/Gad.12.14.2222 |
0.455 |
|
| 1998 |
Li C, Manley JL. Even-skipped represses transcription by binding TATA binding protein and blocking the TFIID-TATA box interaction. Molecular and Cellular Biology. 18: 3771-81. PMID 9632760 DOI: 10.1128/Mcb.18.7.3771 |
0.447 |
|
| 1998 |
Sun JS, Valadkhan S, Manley JL. A UV-crosslinkable interaction in human U6 snRNA. Rna (New York, N.Y.). 4: 489-97. PMID 9582092 DOI: 10.1017/S1355838298980141 |
0.686 |
|
| 1998 |
Tacke R, Tohyama M, Ogawa S, Manley JL. Human Tra2 proteins are sequence-specific activators of pre-mRNA splicing. Cell. 93: 139-48. PMID 9546399 DOI: 10.1016/S0092-8674(00)81153-8 |
0.502 |
|
| 1998 |
Jayaraman L, Moorthy NC, Murthy KG, Manley JL, Bustin M, Prives C. High mobility group protein-1 (HMG-1) is a unique activator of p53. Genes & Development. 12: 462-72. PMID 9472015 DOI: 10.1101/Gad.12.4.462 |
0.355 |
|
| 1998 |
Colgan DF, Murthy KG, Zhao W, Prives C, Manley JL. Inhibition of poly(A) polymerase requires p34cdc2/cyclin B phosphorylation of multiple consensus and non-consensus sites. The Embo Journal. 17: 1053-62. PMID 9463383 DOI: 10.1093/Emboj/17.4.1053 |
0.336 |
|
| 1997 |
Hirose Y, Manley JL. Creatine phosphate, not ATP, is required for 3' end cleavage of mammalian pre-mRNA in vitro. The Journal of Biological Chemistry. 272: 29636-42. PMID 9368030 DOI: 10.1074/Jbc.272.47.29636 |
0.421 |
|
| 1997 |
Colgan DF, Manley JL. Mechanism and regulation of mRNA polyadenylation. Genes & Development. 11: 2755-66. PMID 9353246 DOI: 10.1101/Gad.11.21.2755 |
0.362 |
|
| 1997 |
Dantonel JC, Murthy KG, Manley JL, Tora L. Transcription factor TFIID recruits factor CPSF for formation of 3' end of mRNA. Nature. 389: 399-402. PMID 9311784 DOI: 10.1038/38763 |
0.51 |
|
| 1997 |
Takagaki Y, Manley JL. RNA recognition by the human polyadenylation factor CstF. Molecular and Cellular Biology. 17: 3907-14. PMID 9199325 DOI: 10.1128/Mcb.17.7.3907 |
0.452 |
|
| 1997 |
Sun JS, Manley JL. The human U6 snRNA intramolecular helix: structural constraints and lack of sequence specificity. Rna (New York, N.Y.). 3: 514-26. PMID 9149232 |
0.324 |
|
| 1997 |
Wang J, Manley JL. Regulation of pre-mRNA splicing in metazoa. Current Opinion in Genetics & Development. 7: 205-11. PMID 9115432 DOI: 10.1016/S0959-437X(97)80130-X |
0.442 |
|
| 1997 |
Tacke R, Chen Y, Manley JL. Sequence-specific RNA binding by an SR protein requires RS domain phosphorylation: creation of an SRp40-specific splicing enhancer. Proceedings of the National Academy of Sciences of the United States of America. 94: 1148-53. PMID 9037021 DOI: 10.1073/Pnas.94.4.1148 |
0.465 |
|
| 1997 |
Xiao SH, Manley JL. Phosphorylation of the ASF/SF2 RS domain affects both protein-protein and protein-RNA interactions and is necessary for splicing. Genes & Development. 11: 334-44. PMID 9030686 DOI: 10.1101/Gad.11.3.334 |
0.416 |
|
| 1996 |
Manley JL, Takagaki Y. The end of the message--another link between yeast and mammals. Science (New York, N.Y.). 274: 1481-2. PMID 8966619 DOI: 10.1126/Science.274.5292.1481 |
0.409 |
|
| 1996 |
Takagaki Y, Seipelt RL, Peterson ML, Manley JL. The polyadenylation factor CstF-64 regulates alternative processing of IgM heavy chain pre-mRNA during B cell differentiation. Cell. 87: 941-52. PMID 8945520 DOI: 10.1016/S0092-8674(00)82000-0 |
0.355 |
|
| 1996 |
Farmer G, Friedlander P, Colgan J, Manley JL, Prives C. Transcriptional repression by p53 involves molecular interactions distinct from those with the TATA box binding protein. Nucleic Acids Research. 24: 4281-8. PMID 8932384 DOI: 10.1093/Nar/24.21.4281 |
0.408 |
|
| 1996 |
Colgan DF, Murthy KG, Prives C, Manley JL. Cell-cycle related regulation of poly(A) polymerase by phosphorylation. Nature. 384: 282-5. PMID 8918882 DOI: 10.1038/384282A0 |
0.465 |
|
| 1996 |
Wang J, Takagaki Y, Manley JL. Targeted disruption of an essential vertebrate gene: ASF/SF2 is required for cell viability. Genes & Development. 10: 2588-99. PMID 8895660 DOI: 10.1101/GAD.10.20.2588 |
0.317 |
|
| 1996 |
Norris JL, Manley JL. Functional interactions between the pelle kinase, Toll receptor, and tube suggest a mechanism for activation of dorsal. Genes & Development. 10: 862-72. PMID 8846922 DOI: 10.1101/Gad.10.7.862 |
0.364 |
|
| 1996 |
Farmer G, Colgan J, Nakatani Y, Manley JL, Prives C. Functional interaction between p53, the TATA-binding protein (TBP), andTBP-associated factors in vivo. Molecular and Cellular Biology. 16: 4295-304. PMID 8754830 DOI: 10.1128/Mcb.16.8.4295 |
0.414 |
|
| 1996 |
Manley JL, Um M, Li C, Ashali H. Mechanisms of transcriptional activation and repression can both involve TFIID. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 351: 517-26. PMID 8735274 DOI: 10.1098/Rstb.1996.0050 |
0.671 |
|
| 1996 |
Manley JL, Tacke R. SR proteins and splicing control. Genes & Development. 10: 1569-79. PMID 8682289 DOI: 10.1101/Gad.10.13.1569 |
0.32 |
|
| 1996 |
Zhao W, Manley JL. Complex alternative RNA processing generates an unexpected diversity of poly(A) polymerase isoforms. Molecular and Cellular Biology. 16: 2378-86. PMID 8628305 DOI: 10.1128/Mcb.16.5.2378 |
0.447 |
|
| 1996 |
Colwill K, Pawson T, Andrews B, Prasad J, Manley JL, Bell JC, Duncan PI. The Clk/Sty protein kinase phosphorylates SR splicing factors and regulates their intranuclear distribution. The Embo Journal. 15: 265-75. PMID 8617202 DOI: 10.1002/J.1460-2075.1996.Tb00357.X |
0.377 |
|
| 1996 |
Lutz CS, Murthy KG, Schek N, O'Connor JP, Manley JL, Alwine JC. Interaction between the U1 snRNP-A protein and the 160-kD subunit of cleavage-polyadenylation specificity factor increases polyadenylation efficiency in vitro. Genes & Development. 10: 325-37. PMID 8595883 DOI: 10.1101/Gad.10.3.325 |
0.485 |
|
| 1995 |
Colgan J, Manley JL. Cooperation between core promoter elements influences transcriptional activity in vivo. Proceedings of the National Academy of Sciences of the United States of America. 92: 1955-9. PMID 7892207 DOI: 10.1073/Pnas.92.6.1955 |
0.37 |
|
| 1995 |
Manley JL. Messenger RNA polyadenylylation: a universal modification. Proceedings of the National Academy of Sciences of the United States of America. 92: 1800-1. PMID 7892180 DOI: 10.1073/Pnas.92.6.1800 |
0.404 |
|
| 1995 |
Colgan J, Ashali H, Manley JL. A direct interaction between a glutamine-rich activator and the N terminus of TFIIB can mediate transcriptional activation in vivo. Molecular and Cellular Biology. 15: 2311-20. PMID 7891725 DOI: 10.1128/Mcb.15.4.2311 |
0.426 |
|
| 1995 |
Norris JL, Manley JL. Regulation of dorsal in cultured cells by Toll and tube: tube function involves a novel mechanism. Genes & Development. 9: 358-69. PMID 7867932 DOI: 10.1101/Gad.9.3.358 |
0.364 |
|
| 1995 |
Jamison SF, Pasman Z, Wang J, Will C, Lührmann R, Manley JL, Garcia-Blanco MA. U1 snRNP-ASF/SF2 interaction and 5' splice site recognition: characterization of required elements. Nucleic Acids Research. 23: 3260-7. PMID 7667103 DOI: 10.1093/Nar/23.16.3260 |
0.49 |
|
| 1995 |
Um M, Li C, Manley JL. The transcriptional repressor even-skipped interacts directly with TATA-binding protein. Molecular and Cellular Biology. 15: 5007-16. PMID 7651419 DOI: 10.1128/Mcb.15.9.5007 |
0.66 |
|
| 1995 |
Manley JL. A complex protein assembly catalyzes polyadenylation of mRNA precursors. Current Opinion in Genetics & Development. 5: 222-8. PMID 7613093 DOI: 10.1016/0959-437X(95)80012-3 |
0.481 |
|
| 1995 |
Tacke R, Manley JL. The human splicing factors ASF/SF2 and SC35 possess distinct, functionally significant RNA binding specificities. The Embo Journal. 14: 3540-51. PMID 7543047 DOI: 10.1002/J.1460-2075.1995.Tb07360.X |
0.492 |
|
| 1995 |
Wang J, Manley JL. Overexpression of the SR proteins ASF/SF2 and SC35 influences alternative splicing in vivo in diverse ways. Rna (New York, N.Y.). 1: 335-46. PMID 7489505 |
0.36 |
|
| 1994 |
Raabe T, Murthy KG, Manley JL. Poly(A) polymerase contains multiple functional domains. Molecular and Cellular Biology. 14: 2946-57. PMID 8164653 DOI: 10.1128/Mcb.14.5.2946 |
0.467 |
|
| 1994 |
Kohtz JD, Jamison SF, Will CL, Zuo P, Lührmann R, Garcia-Blanco MA, Manley JL. Protein-protein interactions and 5'-splice-site recognition in mammalian mRNA precursors. Nature. 368: 119-24. PMID 8139654 DOI: 10.1038/368119A0 |
0.49 |
|
| 1994 |
Takagaki Y, Manley JL. A polyadenylation factor subunit is the human homologue of the Drosophila suppressor of forked protein. Nature. 372: 471-4. PMID 7984242 DOI: 10.1038/372471A0 |
0.395 |
|
| 1994 |
Zuo P, Manley JL. The human splicing factor ASF/SF2 can specifically recognize pre-mRNA 5' splice sites. Proceedings of the National Academy of Sciences of the United States of America. 91: 3363-7. PMID 7512732 DOI: 10.1073/Pnas.91.8.3363 |
0.494 |
|
| 1993 |
Colgan J, Wampler S, Manley JL. Interaction between a transcriptional activator and transcription factor IIB in vivo. Nature. 362: 549-53. PMID 8464496 DOI: 10.1038/362549A0 |
0.502 |
|
| 1993 |
Han K, Manley JL. Functional domains of the Drosophila Engrailed protein. The Embo Journal. 12: 2723-33. PMID 8334991 DOI: 10.1002/J.1460-2075.1993.Tb05934.X |
0.425 |
|
| 1993 |
Woppmann A, Will CL, Kornstädt U, Zuo P, Manley JL, Lührmann R. Identification of an snRNP-associated kinase activity that phosphorylates arginine/serine rich domains typical of splicing factors. Nucleic Acids Research. 21: 2815-22. PMID 8332490 DOI: 10.1093/Nar/21.12.2815 |
0.346 |
|
| 1993 |
Zuo P, Manley JL. Functional domains of the human splicing factor ASF/SF2. The Embo Journal. 12: 4727-37. PMID 8223481 DOI: 10.1002/J.1460-2075.1993.Tb06161.X |
0.473 |
|
| 1993 |
Han K, Manley JL. Transcriptional repression by the Drosophila even-skipped protein: definition of a minimal repression domain. Genes & Development. 7: 491-503. PMID 8095483 DOI: 10.1101/Gad.7.3.491 |
0.429 |
|
| 1992 |
Takagaki Y, MacDonald CC, Shenk T, Manley JL. The human 64-kDa polyadenylylation factor contains a ribonucleoprotein-type RNA binding domain and unusual auxiliary motifs. Proceedings of the National Academy of Sciences of the United States of America. 89: 1403-7. PMID 1741396 DOI: 10.1073/Pnas.89.4.1403 |
0.466 |
|
| 1992 |
Colgan J, Manley JL. TFIID can be rate limiting in vivo for TATA-containing, but not TATA-lacking, RNA polymerase II promoters. Genes & Development. 6: 304-15. PMID 1737620 DOI: 10.1101/Gad.6.2.304 |
0.417 |
|
| 1992 |
Harper JE, Manley JL. Multiple activities of the human splicing factor ASF. Gene Expression. 2: 19-29. PMID 1535526 |
0.32 |
|
| 1992 |
Read D, Manley JL. Transcriptional regulators of Drosophila embryogenesis. Biochimica Et Biophysica Acta. 1114: 79-93. PMID 1457465 DOI: 10.1016/0304-419X(92)90008-M |
0.384 |
|
| 1992 |
Read D, Levine M, Manley JL. Ectopic expression of the Drosophila tramtrack gene results in multiple embryonic defects, including repression of even-skipped and fushi tarazu. Mechanisms of Development. 38: 183-95. PMID 1457380 DOI: 10.1016/0925-4773(92)90052-L |
0.412 |
|
| 1992 |
Wu J, Manley JL. Multiple functional domains of human U2 small nuclear RNA: strengthening conserved stem I can block splicing. Molecular and Cellular Biology. 12: 5464-73. PMID 1448079 DOI: 10.1128/Mcb.12.12.5464 |
0.455 |
|
| 1992 |
Read D, Manley JL. Alternatively spliced transcripts of the Drosophila tramtrack gene encode zinc finger proteins with distinct DNA binding specificities. The Embo Journal. 11: 1035-44. PMID 1372245 DOI: 10.1002/J.1460-2075.1992.Tb05142.X |
0.435 |
|
| 1992 |
Kim YJ, Zuo P, Manley JL, Baker BS. The Drosophila RNA-binding protein RBP1 is localized to transcriptionally active sites of chromosomes and shows a functional similarity to human splicing factor ASF/SF2. Genes & Development. 6: 2569-79. PMID 1340470 DOI: 10.1101/Gad.6.12B.2569 |
0.427 |
|
| 1991 |
Raabe T, Bollum FJ, Manley JL. Primary structure and expression of bovine poly(A) polymerase. Nature. 353: 229-34. PMID 1896071 DOI: 10.1038/353229A0 |
0.49 |
|
| 1991 |
Ge H, Zuo P, Manley JL. Primary structure of the human splicing factor ASF reveals similarities with Drosophila regulators. Cell. 66: 373-82. PMID 1855257 DOI: 10.1016/0092-8674(91)90626-A |
0.473 |
|
| 1991 |
Wu JA, Manley JL. Base pairing between U2 and U6 snRNAs is necessary for splicing of a mammalian pre-mRNA. Nature. 352: 818-21. PMID 1831878 DOI: 10.1038/352818A0 |
0.466 |
|
| 1991 |
Zuo P, Stanojević D, Colgan J, Han K, Levine M, Manley JL. Activation and repression of transcription by the gap proteins hunchback and Krüppel in cultured Drosophila cells. Genes & Development. 5: 254-64. PMID 1671661 DOI: 10.1101/Gad.5.2.254 |
0.44 |
|
| 1991 |
Harper JE, Manley JL. A novel protein factor is required for use of distal alternative 5' splice sites in vitro. Molecular and Cellular Biology. 11: 5945-53. PMID 1658620 |
0.339 |
|
| 1990 |
Read D, Nishigaki T, Manley JL. The Drosophila even-skipped promoter is transcribed in a stage-specific manner in vitro and contains multiple, overlapping factor-binding sites. Molecular and Cellular Biology. 10: 4334-44. PMID 2370868 DOI: 10.1128/Mcb.10.8.4334 |
0.389 |
|
| 1990 |
Wilusz J, Shenk T, Takagaki Y, Manley JL. A multicomponent complex is required for the AAUAAA-dependent cross-linking of a 64-kilodalton protein to polyadenylation substrates. Molecular and Cellular Biology. 10: 1244-8. PMID 2304466 DOI: 10.1128/Mcb.10.3.1244 |
0.348 |
|
| 1990 |
Harper JE, Miceli SM, Roberts RJ, Manley JL. Sequence specificity of the human mRNA N6-adenosine methylase in vitro. Nucleic Acids Research. 18: 5735-41. PMID 2216767 DOI: 10.1093/Nar/18.19.5735 |
0.393 |
|
| 1990 |
Ge H, Manley JL. A protein factor, ASF, controls cell-specific alternative splicing of SV40 early pre-mRNA in vitro. Cell. 62: 25-34. PMID 2163768 DOI: 10.1016/0092-8674(90)90236-8 |
0.417 |
|
| 1990 |
Ge H, Noble J, Colgan J, Manley JL. Polyoma virus small tumor antigen pre-mRNA splicing requires cooperation between two 3' splice sites. Proceedings of the National Academy of Sciences of the United States of America. 87: 3338-42. PMID 2159146 DOI: 10.1073/Pnas.87.9.3338 |
0.466 |
|
| 1990 |
Takagaki Y, Manley JL, MacDonald CC, Wilusz J, Shenk T. A multisubunit factor, CstF, is required for polyadenylation of mammalian pre-mRNAs. Genes & Development. 4: 2112-20. PMID 1980119 DOI: 10.1101/Gad.4.12A.2112 |
0.498 |
|
| 1989 |
Connelly S, Manley JL. A CCAAT box sequence in the adenovirus major late promoter functions as part of an RNA polymerase II termination signal. Cell. 57: 561-71. PMID 2720783 DOI: 10.1016/0092-8674(89)90126-8 |
0.46 |
|
| 1989 |
Manley JL, Proudfoot NJ, Platt T. RNA 3'-end formation. Genes & Development. 3: 2218-22. PMID 2628168 DOI: 10.1101/Gad.3.12B.2218 |
0.406 |
|
| 1989 |
Connelly S, Manley JL. RNA polymerase II transcription termination is mediated specifically by protein binding to a CCAAT box sequence. Molecular and Cellular Biology. 9: 5254-9. PMID 2601722 DOI: 10.1128/Mcb.9.11.5254 |
0.493 |
|
| 1989 |
Rushlow CA, Han K, Manley JL, Levine M. The graded distribution of the dorsal morphogen is initiated by selective nuclear transport in Drosophila. Cell. 59: 1165-77. PMID 2598265 DOI: 10.1016/0092-8674(89)90772-1 |
0.342 |
|
| 1989 |
Levine M, Manley JL. Transcriptional repression of eukaryotic promoters. Cell. 59: 405-8. PMID 2572326 DOI: 10.1016/0092-8674(89)90024-X |
0.336 |
|
| 1989 |
Ryner LC, Takagaki Y, Manley JL. Sequences downstream of AAUAAA signals affect pre-mRNA cleavage and polyadenylation in vitro both directly and indirectly. Molecular and Cellular Biology. 9: 1759-71. PMID 2566911 DOI: 10.1128/Mcb.9.4.1759 |
0.4 |
|
| 1989 |
Han K, Levine MS, Manley JL. Synergistic activation and repression of transcription by Drosophila homeobox proteins. Cell. 56: 573-83. PMID 2563673 DOI: 10.1016/0092-8674(89)90580-1 |
0.421 |
|
| 1989 |
Wu J, Manley JL. Mammalian pre-mRNA branch site selection by U2 snRNP involves base pairing. Genes & Development. 3: 1553-61. PMID 2558966 DOI: 10.1101/Gad.3.10.1553 |
0.379 |
|
| 1989 |
Takagaki Y, Ryner LC, Manley JL. Four factors are required for 3'-end cleavage of pre-mRNAs. Genes & Development. 3: 1711-24. PMID 2558045 DOI: 10.1101/Gad.3.11.1711 |
0.44 |
|
| 1989 |
Ryner LC, Takagaki Y, Manley JL. Multiple forms of poly(A) polymerases purified from HeLa cells function in specific mRNA 3'-end formation. Molecular and Cellular Biology. 9: 4229-38. PMID 2555686 DOI: 10.1128/Mcb.9.10.4229 |
0.372 |
|
| 1989 |
Pan ZQ, Ge H, Fu XY, Manley JL, Prives C. Oligonucleotide-targeted degradation of U1 and U2 snRNAs reveals differential interactions of simian virus 40 pre-mRNAs with snRNPs. Nucleic Acids Research. 17: 6553-68. PMID 2550896 DOI: 10.1093/Nar/17.16.6553 |
0.433 |
|
| 1989 |
Noble JC, Ge H, Chaudhuri M, Manley JL. Factor interactions with the simian virus 40 early pre-mRNA influence branch site selection and alternative splicing. Molecular and Cellular Biology. 9: 2007-17. PMID 2546057 DOI: 10.1128/mcb.9.5.2007-2017.1989 |
0.418 |
|
| 1988 |
Manley JL. Polyadenylation of mRNA precursors. Biochimica Et Biophysica Acta. 950: 1-12. PMID 2896017 DOI: 10.1016/0167-4781(88)90067-X |
0.343 |
|
| 1988 |
Fu XY, Colgan JD, Manley JL. Multiple cis-acting sequence elements are required for efficient splicing of simian virus 40 small-t antigen pre-mRNA. Molecular and Cellular Biology. 8: 3582-90. PMID 2851720 DOI: 10.1128/Mcb.8.9.3582 |
0.339 |
|
| 1988 |
Noble JC, Prives C, Manley JL. Alternative splicing of SV40 early pre-mRNA is determined by branch site selection. Genes & Development. 2: 1460-75. PMID 2850262 DOI: 10.1101/Gad.2.11.1460 |
0.432 |
|
| 1988 |
Fu XY, Ge H, Manley JL. The role of the polypyrimidine stretch at the SV40 early pre-mRNA 3' splice site in alternative splicing. The Embo Journal. 7: 809-17. PMID 2840286 DOI: 10.1002/J.1460-2075.1988.Tb02879.X |
0.405 |
|
| 1988 |
Connelly S, Manley JL. A functional mRNA polyadenylation signal is required for transcription termination by RNA polymerase II. Genes & Development. 2: 440-52. PMID 2836265 |
0.407 |
|
| 1988 |
Takagaki Y, Ryner LC, Manley JL. Separation and characterization of a poly(A) polymerase and a cleavage/specificity factor required for pre-mRNA polyadenylation. Cell. 52: 731-42. PMID 2830992 DOI: 10.1016/0092-8674(88)90411-4 |
0.434 |
|
| 1987 |
Noble JC, Pan ZQ, Prives C, Manley JL. Splicing of SV40 early pre-mRNA to large T and small t mRNAs utilizes different patterns of lariat branch sites. Cell. 50: 227-36. PMID 3036371 DOI: 10.1016/0092-8674(87)90218-2 |
0.365 |
|
| 1987 |
Grass DS, Jove R, Manley JL. RNA polymerase II terminates transcription in vitro in the SV40 origin region. Nucleic Acids Research. 15: 4417-36. PMID 3035493 DOI: 10.1093/Nar/15.11.4417 |
0.509 |
|
| 1987 |
Ryner LC, Manley JL. Requirements for accurate and efficient mRNA 3' end cleavage and polyadenylation of a simian virus 40 early pre-RNA in vitro. Molecular and Cellular Biology. 7: 495-503. PMID 3031477 |
0.374 |
|
| 1987 |
Fu XY, Manley JL. Factors influencing alternative splice site utilization in vivo. Molecular and Cellular Biology. 7: 738-48. PMID 3029566 DOI: 10.1128/Mcb.7.2.738 |
0.395 |
|
| 1987 |
Grass DS, Read D, Lewis ED, Manley JL. Cell- and promoter-specific activation of transcription by DNA replication. Genes & Development. 1: 1065-74. PMID 2828163 DOI: 10.1101/Gad.1.10.1065 |
0.414 |
|
| 1986 |
Yu YT, Manley JL. Structure and function of the S1 nuclease-sensitive site in the adenovirus late promoter. Cell. 45: 743-51. PMID 3011277 DOI: 10.1016/0092-8674(86)90788-9 |
0.378 |
|
| 1986 |
Noble JC, Prives C, Manley JL. In vitro splicing of simian virus 40 early pre mRNA. Nucleic Acids Research. 14: 1219-35. PMID 3005968 DOI: 10.1093/Nar/14.3.1219 |
0.396 |
|
| 1986 |
Lewis ED, Manley JL. Polyadenylylation of an mRNA precursor occurs independently of transcription by RNA polymerase II in vivo. Proceedings of the National Academy of Sciences of the United States of America. 83: 8555-9. PMID 2877459 |
0.418 |
|
| 1985 |
Lewis ED, Manley JL. Repression of simian virus 40 early transcription by viral DNA replication in human 293 cells. Nature. 317: 172-5. PMID 2993922 DOI: 10.1038/317172A0 |
0.326 |
|
| 1985 |
Manley JL, Yu H, Ryner L. RNA sequence containing hexanucleotide AAUAAA directs efficient mRNA polyadenylation in vitro. Molecular and Cellular Biology. 5: 373-9. PMID 2579321 |
0.379 |
|
| 1984 |
Jove R, Manley JL. In vitro transcription from the adenovirus 2 major late promoter utilizing templates truncated at promoter-proximal sites. The Journal of Biological Chemistry. 259: 8513-21. PMID 6736040 |
0.404 |
|
| 1984 |
Yu YT, Manley JL. Generation and functional analyses for base-substitution mutants of the adenovirus 2 major late promoter. Nucleic Acids Research. 12: 9309-21. PMID 6514578 DOI: 10.1093/Nar/12.24.9309 |
0.409 |
|
| 1984 |
Jove R, Sperber DE, Manley JL. Transcription of methylated eukaryotic viral genes in a soluble in vitro system. Nucleic Acids Research. 12: 4715-30. PMID 6330681 DOI: 10.1093/Nar/12.11.4715 |
0.388 |
|
| 1984 |
Fradin A, Jove R, Hemenway C, Keiser HD, Manley JL, Prives C. Splicing pathways of SV40 mRNAs in X. laevis oocytes differ in their requirements for snRNPs. Cell. 37: 927-36. PMID 6086149 DOI: 10.1016/0092-8674(84)90427-6 |
0.456 |
|
| 1983 |
Mitsialis SA, Manley JL, Guntaka RV. Localization of active promoters for eucaryotic RNA polymerase II in the long terminal repeat of avian sarcoma virus DNA. Molecular and Cellular Biology. 3: 811-8. PMID 6306447 |
0.394 |
|
| 1983 |
Manley JL. Analysis of the expression of genes encoding animal mRNA by in vitro techniques. Progress in Nucleic Acid Research and Molecular Biology. 30: 195-244. PMID 6198693 DOI: 10.1016/S0079-6603(08)60687-X |
0.457 |
|
| 1983 |
Manley JL, Fire A, Samuels M, Sharp PA. In vitro transcription: whole-cell extract. Methods in Enzymology. 101: 568-82. PMID 6193397 DOI: 10.1016/0076-6879(83)01038-1 |
0.421 |
|
| 1983 |
Manley JL. Accurate and specific polyadenylation of mRNA precursors in a soluble whole-cell lysate. Cell. 33: 595-605. PMID 6134588 DOI: 10.1016/0092-8674(83)90440-3 |
0.455 |
|
| 1982 |
Manley JL, Colozzo MT. Synthesis in vitro of an exceptionally long RNA transcript promoted by an AluI sequence. Nature. 300: 376-9. PMID 7144892 DOI: 10.1038/300376A0 |
0.492 |
|
| 1982 |
Jove R, Manley JL. Transcription initiation by RNA polymerase II is inhibited by S-adenosylhomocysteine. Proceedings of the National Academy of Sciences of the United States of America. 79: 5842-6. PMID 6964391 DOI: 10.1073/Pnas.79.19.5842 |
0.492 |
|
| 1982 |
Hough PV, Mastrangelo IA, Wall JS, Hainfeld JF, Simon MN, Manley JL. DNA-protein complexes spread on N2-discharged carbon film and characterized by molecular weight and its projected distribution. Journal of Molecular Biology. 160: 375-86. PMID 6757448 DOI: 10.1016/0022-2836(82)90183-8 |
0.399 |
|
| 1982 |
Fradin A, Manley JL, Prives CL. Methylation of simian virus 40 Hpa II site affects late, but not early, viral gene expression. Proceedings of the National Academy of Sciences of the United States of America. 79: 5142-6. PMID 6291026 DOI: 10.1073/Pnas.79.17.5142 |
0.343 |
|
| 1982 |
Manley JL, Sharp PA, Gefter ML. Rna synthesis in isolated nuclei processing of adenovirus serotype 2 late messenger rna precursors. Journal of Molecular Biology. 159: 581-99. PMID 6183434 DOI: 10.1016/0022-2836(82)90102-4 |
0.643 |
|
| 1981 |
Sharp PA, Manley J, Fire A, Gefter M. Regulation of adenovirus mRNA synthesis. Annals of the New York Academy of Sciences. 354: 1-15. PMID 7013617 DOI: 10.1111/J.1749-6632.1980.Tb27954.X |
0.658 |
|
| 1981 |
Spritz RA, Jagadeeswaran P, Choudary PV, Biro PA, Elder JT, deRiel JK, Manley JL, Gefter ML, Forget BG, Weissman SM. Base substitution in an intervening sequence of a beta+-thalassemic human globin gene. Proceedings of the National Academy of Sciences of the United States of America. 78: 2455-9. PMID 6264477 DOI: 10.1073/Pnas.78.4.2455 |
0.544 |
|
| 1981 |
Manley JL, Gefter ML. Transcription of mammalian genes in vitro. Gene Amplification and Analysis. 2: 369-82. PMID 6101055 |
0.588 |
|
| 1980 |
Manley JL, Fire A, Cano A, Sharp PA, Gefter ML. DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract. Proceedings of the National Academy of Sciences of the United States of America. 77: 3855-9. PMID 6933441 DOI: 10.1073/Pnas.77.7.3855 |
0.698 |
|
| 1980 |
Proudfoot NJ, Shander MH, Manley JL, Gefter ML, Maniatis T. Structure and in vitro transcription of human globin genes. Science (New York, N.Y.). 209: 1329-36. PMID 6158093 DOI: 10.1126/Science.6158093 |
0.547 |
|
| 1979 |
Manley JL, Sharp PA, Gefter ML. RNA synthesis in isolated nuclei: identification and comparison of adenovirus 2 encoded transcripts synthesized in vitro and vivo. Journal of Molecular Biology. 135: 171-97. PMID 529286 DOI: 10.1016/0022-2836(79)90346-2 |
0.655 |
|
| 1979 |
Manley JL, Sharp PA, Gefter ML. RNA synthesis in isolated nuclei: in vitro initiation of adenovirus 2 major late mRNA precursor. Proceedings of the National Academy of Sciences of the United States of America. 76: 160-4. PMID 284328 DOI: 10.1073/Pnas.76.1.160 |
0.644 |
|
| 1978 |
Manley JL, Gesteland RF. Suppression of amber mutants in vitro induced by low temperature. Journal of Molecular Biology. 125: 433-47. PMID 105144 DOI: 10.1016/0022-2836(78)90309-1 |
0.516 |
|
| 1973 |
Manley J, Reiness G, Zubay G, Gefter ML. Cell-free synthesis of SU+ III tyrosyl transfer RNA: Characterization of the 4S product Archives of Biochemistry and Biophysics. 157: 50-54. PMID 4716962 DOI: 10.1016/0003-9861(73)90388-3 |
0.795 |
|
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