Year |
Citation |
Score |
2024 |
Shantaraman A, Dammer EB, Ugochukwu O, Duong DM, Yin L, Carter EK, Gearing M, Chen-Plotkin A, Lee EB, Trojanowski JQ, Bennett DA, Lah JJ, Levey AI, Seyfried NT, Higginbotham L. Correction: Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer's disease. Molecular Neurodegeneration. 19: 71. PMID 39394136 DOI: 10.1186/s13024-024-00765-1 |
0.694 |
|
2024 |
Chen-Plotkin A, Kannarkat G, Zack R, Skrinak RT, Morley J, Davila-Rivera R, Arezoumandan S, Luk K, Wolk D, Weintraub D, Tropea T, Lee E, Xie S, Chandrasekaran G, Lee V, et al. Alpha-Synuclein Conformations in Plasma Distinguish Parkinson's Disease from Dementia with Lewy Bodies. Research Square. PMID 39372921 DOI: 10.21203/rs.3.rs-5033901/v1 |
0.672 |
|
2024 |
Kovacs GG, Grinberg LT, Halliday G, Alafuzoff I, Dugger BN, Murayama S, Forrest SL, Martinez-Valbuena I, Tanaka H, Kon T, Yoshida K, Jaunmuktane Z, Spina S, Nelson PT, Gentleman S, ... ... Lee EB, et al. Biomarker-Based Approach to α-Synucleinopathies: Lessons from Neuropathology. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 39360851 DOI: 10.1002/mds.30028 |
0.544 |
|
2024 |
Khandelwal P, Duong MT, Sadaghiani S, Lim S, Denning AE, Chung E, Ravikumar S, Arezoumandan S, Peterson C, Bedard M, Capp N, Ittyerah R, Migdal E, Choi G, Kopp E, ... ... Lee EB, et al. Automated deep learning segmentation of high-resolution 7 Tesla postmortem MRI for quantitative analysis of structure-pathology correlations in neurodegenerative diseases. Imaging Neuroscience (Cambridge, Mass.). 2: 1-30. PMID 39301426 DOI: 10.1162/imag_a_00171 |
0.474 |
|
2024 |
Rexach JE, Cheng Y, Chen L, Polioudakis D, Lin LC, Mitri V, Elkins A, Han X, Yamakawa M, Yin A, Calini D, Kawaguchi R, Ou J, Huang J, Williams C, ... ... Lee EB, et al. Cross-disorder and disease-specific pathways in dementia revealed by single-cell genomics. Cell. PMID 39265576 DOI: 10.1016/j.cell.2024.08.019 |
0.57 |
|
2024 |
Denning AE, Ittyerah R, Levorse LM, Sadeghpour N, Athalye C, Chung E, Ravikumar S, Dong M, Duong MT, Li Y, Ilesanmi A, Sreepada LP, Sabatini P, Lowe M, Bahena A, ... ... Lee EB, et al. Association of quantitative histopathology measurements with antemortem medial temporal lobe cortical thickness in the Alzheimer's disease continuum. Acta Neuropathologica. 148: 37. PMID 39227502 DOI: 10.1007/s00401-024-02789-9 |
0.774 |
|
2024 |
Reddy JS, Heath L, Linden AV, Allen M, Lopes KP, Seifar F, Wang E, Ma Y, Poehlman WL, Quicksall ZS, Runnels A, Wang Y, Duong DM, Yin L, Xu K, ... ... Lee EB, et al. Bridging the gap: Multi-omics profiling of brain tissue in Alzheimer's disease and older controls in multi-ethnic populations. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 39215503 DOI: 10.1002/alz.14208 |
0.665 |
|
2024 |
Duan P, Dregni AJ, Xu H, Changolkar L, Lee VM, Lee EB, Hong M. Alzheimer's Disease Seeded Tau Forms Paired Helical Filaments Yet Lacks Seeding Potential. The Journal of Biological Chemistry. 107730. PMID 39214304 DOI: 10.1016/j.jbc.2024.107730 |
0.653 |
|
2024 |
Ohm DT, Xie SX, Capp N, Arezoumandan S, Cousins KAQ, Rascovsky K, Wolk DA, Van Deerlin VM, Lee EB, McMillan CT, Irwin DJ. Cytoarchitectonic gradients of laminar degeneration in behavioural variant frontotemporal dementia. Brain : a Journal of Neurology. PMID 39119853 DOI: 10.1093/brain/awae263 |
0.763 |
|
2024 |
Shantaraman A, Dammer EB, Ugochukwu O, Duong DM, Yin L, Carter EK, Gearing M, Chen-Plotkin A, Lee EB, Trojanowski JQ, Bennett DA, Lah JJ, Levey AI, Seyfried NT, Higginbotham L. Network proteomics of the Lewy body dementia brain reveals presynaptic signatures distinct from Alzheimer's disease. Molecular Neurodegeneration. 19: 60. PMID 39107789 DOI: 10.1186/s13024-024-00749-1 |
0.727 |
|
2024 |
Pottier C, Küçükali F, Baker M, Batzler A, Jenkins GD, van Blitterswijk M, Vicente CT, De Coster W, Wynants S, Van de Walle P, Ross OA, Murray ME, Faura J, Haggarty SJ, van Rooij JG, ... ... Lee EB, et al. Deciphering Distinct Genetic Risk Factors for FTLD-TDP Pathological Subtypes via Whole-Genome Sequencing. Medrxiv : the Preprint Server For Health Sciences. PMID 38978643 DOI: 10.1101/2024.06.24.24309088 |
0.479 |
|
2024 |
Ravikumar S, Denning AE, Lim S, Chung E, Sadeghpour N, Ittyerah R, Wisse LEM, Das SR, Xie L, Robinson JL, Schuck T, Lee EB, Detre JA, Tisdall MD, Prabhakaran K, et al. Postmortem imaging reveals patterns of medial temporal lobe vulnerability to tau pathology in Alzheimer's disease. Nature Communications. 15: 4803. PMID 38839876 DOI: 10.1038/s41467-024-49205-0 |
0.359 |
|
2024 |
Phan JM, Creekmore BC, Nguyen AT, Bershadskaya DD, Darwich NF, Mann CN, Lee EB. VCP activator reverses nuclear proteostasis defects and enhances TDP-43 aggregate clearance in multisystem proteinopathy models. The Journal of Clinical Investigation. PMID 38787785 DOI: 10.1172/JCI169039 |
0.703 |
|
2024 |
Tosun D, Hausle Z, Iwaki H, Thropp P, Lamoureux J, Lee EB, MacLeod K, McEvoy S, Nalls M, Perrin RJ, Saykin AJ, Shaw LM, Singleton AB, Lebovitz R, Weiner MW, et al. A cross-sectional study of α-synuclein seed amplification assay in Alzheimer's disease neuroimaging initiative: Prevalence and associations with Alzheimer's disease biomarkers and cognitive function. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38770829 DOI: 10.1002/alz.13858 |
0.404 |
|
2024 |
Kannarkat GT, Zack R, Skrinak RT, Morley JF, Davila-Rivera R, Arezoumandan S, Dorfmann K, Luk K, Wolk DA, Weintraub D, Tropea TF, Lee EB, Xie SX, Chandrasekaran G, Lee VM, et al. α-Synuclein Conformations in Plasma Distinguish Parkinson's Disease from Dementia with Lewy Bodies. Biorxiv : the Preprint Server For Biology. PMID 38765963 DOI: 10.1101/2024.05.07.593056 |
0.687 |
|
2024 |
Wojtas AM, Dammer EB, Guo Q, Ping L, Shantaraman A, Duong DM, Yin L, Fox EJ, Seifar F, Lee EB, Johnson ECB, Lah JJ, Levey AI, Levites Y, Rangaraju S, et al. Proteomic changes in the human cerebrovasculature in Alzheimer's disease and related tauopathies linked to peripheral biomarkers in plasma and cerebrospinal fluid. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38713744 DOI: 10.1002/alz.13821 |
0.337 |
|
2024 |
Santiago-Ruiz AN, Hugelier S, Bond CR, Lee EB, Lakadamyali M. Super-Resolution Imaging Uncovers Nanoscale Tau Aggregate Hyperphosphorylation Patterns in Human Alzheimer's Disease Brain Tissue. Biorxiv : the Preprint Server For Biology. PMID 38712162 DOI: 10.1101/2024.04.24.590893 |
0.373 |
|
2024 |
Seifar F, Fox EJ, Shantaraman A, Liu Y, Dammer EB, Modeste E, Duong DM, Yin L, Trautwig AN, Guo Q, Xu K, Ping L, Reddy JS, Allen M, Quicksall Z, ... ... Lee EB, et al. Large-scale Deep Proteomic Analysis in Alzheimer's Disease Brain Regions Across Race and Ethnicity. Biorxiv : the Preprint Server For Biology. PMID 38712030 DOI: 10.1101/2024.04.22.590547 |
0.674 |
|
2024 |
Reddy JS, Heath L, Linden AV, Allen M, de Paiva Lopes K, Seifar F, Wang E, Ma Y, Poehlman WL, Quicksall ZS, Runnels A, Wang Y, Duong DM, Yin L, Xu K, ... ... Lee EB, et al. Bridging the Gap: Multi-Omics Profiling of Brain Tissue in Alzheimer's Disease and Older Controls in Multi-Ethnic Populations. Biorxiv : the Preprint Server For Biology. PMID 38659743 DOI: 10.1101/2024.04.16.589592 |
0.666 |
|
2024 |
Ohm DT, Xie SX, Capp N, Arezoumandan S, Cousins KAQ, Rascovsky K, Wolk DA, Van Deerlin VM, Lee EB, McMillan CT, Irwin DJ. Cytoarchitectonic gradients of laminar degeneration in behavioral variant frontotemporal dementia. Biorxiv : the Preprint Server For Biology. PMID 38644997 DOI: 10.1101/2024.04.05.588259 |
0.762 |
|
2024 |
Cousins KAQ, Phillips JS, Das SR, O'Brien K, Tropea TF, Chen-Plotkin A, Shaw LM, Nasrallah IM, Mechanic-Hamilton D, McMillan CT, Irwin DJ, Lee EB, Wolk DA. Pathologic and cognitive correlates of plasma biomarkers in neurodegenerative disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38644682 DOI: 10.1002/alz.13777 |
0.721 |
|
2024 |
Parra Bravo C, Giani AM, Perez JM, Zhao Z, Wan Y, Samelson AJ, Wong MY, Evangelisti A, Cordes E, Fan L, Ye P, Zhu D, Pozner T, Mercedes M, Patel T, ... ... Lee EB, et al. Human iPSC 4R tauopathy model uncovers modifiers of tau propagation. Cell. PMID 38582079 DOI: 10.1016/j.cell.2024.03.015 |
0.342 |
|
2024 |
Nazeen S, Wang X, Zielinski D, Lam I, Hallacli E, Xu P, Ethier E, Strom R, Zanella CA, Nithianandam V, Ritter D, Henderson A, Saurat N, Afroz J, Nutter-Upham A, ... ... Lee EB, et al. Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies. Biorxiv : the Preprint Server For Biology. PMID 38496508 DOI: 10.1101/2024.03.03.583145 |
0.542 |
|
2024 |
Xu H, Qiu Q, Hu P, Hoxha K, Jang E, O'Reilly M, Kim C, He Z, Marotta N, Changolkar L, Zhang B, Wu H, Schellenberg GD, Kraemer B, Luk KC, ... Lee EB, et al. MSUT2 regulates tau spreading via adenosinergic signaling mediated ASAP1 pathway in neurons. Acta Neuropathologica. 147: 55. PMID 38472475 DOI: 10.1007/s00401-024-02703-3 |
0.835 |
|
2024 |
Shantaraman A, Dammer EB, Ugochukwu O, Duong DM, Yin L, Carter EK, Gearing M, Chen-Plotkin A, Lee EB, Trojanowski JQ, Bennett DA, Lah JJ, Levey AI, Seyfried NT, Higginbotham L. Network Proteomics of the Lewy Body Dementia Brain Reveals Presynaptic Signatures Distinct from Alzheimer's Disease. Biorxiv : the Preprint Server For Biology. PMID 38328211 DOI: 10.1101/2024.01.23.576728 |
0.727 |
|
2024 |
Arezoumandan S, Cousins KAQ, Ohm DT, Lowe M, Chen M, Gee J, Phillips JS, McMillan CT, Luk KC, Deik A, Spindler MA, Tropea TF, Weintraub D, Wolk DA, Grossman M, ... ... Lee EB, et al. Tau maturation in the clinicopathological spectrum of Lewy body and Alzheimer's disease. Annals of Clinical and Translational Neurology. PMID 38263854 DOI: 10.1002/acn3.51988 |
0.84 |
|
2024 |
Wojtas AM, Dammer EB, Guo Q, Ping L, Shantaraman A, Duong DM, Yin L, Fox EJ, Seifar F, Lee EB, Johnson ECB, Lah JJ, Levey AI, Levites Y, Rangaraju S, et al. Proteomic Changes in the Human Cerebrovasculature in Alzheimer's Disease and Related Tauopathies Linked to Peripheral Biomarkers in Plasma and Cerebrospinal Fluid. Medrxiv : the Preprint Server For Health Sciences. PMID 38260316 DOI: 10.1101/2024.01.10.24301099 |
0.364 |
|
2023 |
Lyu X, Duong MT, Xie L, de Flores R, Richardson H, Hwang G, Wisse LEM, DiCalogero M, McMillan CT, Robinson JL, Xie SX, Lee EB, Irwin DJ, Dickerson BC, Davatzikos C, et al. Tau-neurodegeneration mismatch reveals vulnerability and resilience to comorbidities in Alzheimer's continuum. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38050662 DOI: 10.1002/alz.13559 |
0.659 |
|
2023 |
Phillips JS, Robinson JL, Cousins KAQ, Wolk DA, Lee EB, McMillan CT, Trojanowski JQ, Grossman M, Irwin DJ. Polypathologic associations with grey matter atrophy in neurodegenerative disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 38050082 DOI: 10.1523/JNEUROSCI.0808-23.2023 |
0.607 |
|
2023 |
Ohm DT, Rhodes E, Bahena A, Capp N, Lowe M, Sabatini P, Trotman W, Olm CA, Phillips J, Prabhakaran K, Rascovsky K, Massimo L, McMillan C, Gee J, Tisdall MD, ... ... Lee EB, et al. Neuroanatomical and cellular degeneration associated with a social disorder characterized by new ritualistic belief systems in a TDP-C patient vs. a Pick patient. Frontiers in Neurology. 14: 1245886. PMID 37900607 DOI: 10.3389/fneur.2023.1245886 |
0.752 |
|
2023 |
Stewart W, Buckland ME, Abdolmohammadi B, Affleck AJ, Alvarez VE, Gilchrist S, Huber BR, Lee EB, Lyall DM, Nowinski CJ, Russell ER, Stein TD, Suter CM, McKee AC. Risk of chronic traumatic encephalopathy in rugby union is associated with length of playing career. Acta Neuropathologica. PMID 37872234 DOI: 10.1007/s00401-023-02644-3 |
0.387 |
|
2023 |
Creekmore BC, Watanabe R, Lee EB. Neurodegenerative Disease Tauopathies. Annual Review of Pathology. PMID 37832941 DOI: 10.1146/annurev-pathmechdis-051222-120750 |
0.36 |
|
2023 |
Rexach JE, Cheng Y, Chen L, Polioudakis D, Lin LC, Mitri V, Elkins A, Yin A, Calini D, Kawaguchi R, Ou J, Huang J, Williams C, Robinson J, Gaus SE, ... ... Lee EB, et al. Disease-specific selective vulnerability and neuroimmune pathways in dementia revealed by single cell genomics. Biorxiv : the Preprint Server For Biology. PMID 37808727 DOI: 10.1101/2023.09.29.560245 |
0.568 |
|
2023 |
Kang JH, Korecka M, Lee EB, Cousins KAQ, Tropea TF, Chen-Plotkin AA, Irwin DJ, Wolk D, Brylska M, Wan Y, Shaw LM. Alzheimer Disease Biomarkers: Moving from CSF to Plasma for Reliable Detection of Amyloid and tau Pathology. Clinical Chemistry. PMID 37725909 DOI: 10.1093/clinchem/hvad139 |
0.638 |
|
2023 |
Nguyen AT, Wang K, Hu G, Wang X, Miao Z, Azevedo JA, Suh E, Van Deerlin VM, Choi D, Roeder K, Li M, Lee EB. Correction: APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer's disease. Acta Neuropathologica. PMID 37589745 DOI: 10.1007/s00401-023-02620-x |
0.725 |
|
2023 |
Ash S, Nevler N, Irwin DJ, Shellikeri S, Rascovsky K, Shaw L, Lee EB, Trojanowski JQ, Grossman M. Apraxia of Speech in the Spontaneous Speech of Nonfluent/Agrammatic Primary Progressive Aphasia. Journal of Alzheimer's Disease Reports. 7: 589-604. PMID 37313492 DOI: 10.3233/ADR-220089 |
0.373 |
|
2023 |
Quintin S, Lloyd GM, Paterno G, Xia Y, Sorrentino Z, Bell BM, Gorion KM, Lee EB, Prokop S, Giasson BI. Cellular processing of α-synuclein fibrils results in distinct physiological C-terminal truncations with a major cleavage site at residue Glu 114. The Journal of Biological Chemistry. 104912. PMID 37307916 DOI: 10.1016/j.jbc.2023.104912 |
0.738 |
|
2023 |
Chen M, Burke S, Olm CA, Irwin DJ, Massimo L, Lee EB, Trojanowski JQ, Gee JC, Grossman M. Antemortem network analysis of spreading pathology in autopsy-confirmed frontotemporal degeneration. Brain Communications. 5: fcad147. PMID 37223129 DOI: 10.1093/braincomms/fcad147 |
0.561 |
|
2023 |
Valentino RR, Scotton WJ, Roemer SF, Lashley T, Heckman MG, Shoai M, Martinez-Carrasco A, Tamvaka N, Walton RL, Baker MC, Macpherson HL, Real R, Soto-Beasley AI, Mok K, Revesz T, ... ... Lee EB, et al. Creating the Pick's disease International Consortium: Association study of H2 haplotype with risk of Pick's disease. Medrxiv : the Preprint Server For Health Sciences. PMID 37163045 DOI: 10.1101/2023.04.17.23288471 |
0.732 |
|
2023 |
Young AL, Vogel JW, Robinson JL, McMillan CT, Ossenkoppele R, Wolk DA, Irwin DJ, Elman L, Grossman M, Lee VM, Lee EB, Hansson O. Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies. Brain : a Journal of Neurology. PMID 37150879 DOI: 10.1093/brain/awad145 |
0.575 |
|
2023 |
Cousins KAQ, Irwin DJ, Chen-Plotkin A, Shaw LM, Arezoumandan S, Lee EB, Wolk DA, Weintraub D, Spindler M, Deik A, Grossman M, Tropea TF. Plasma GFAP associates with secondary Alzheimer's pathology in Lewy body disease. Annals of Clinical and Translational Neurology. PMID 37000892 DOI: 10.1002/acn3.51768 |
0.65 |
|
2023 |
Phan JM, Creekmore BC, Nguyen AT, Bershadskaya DD, Darwich NF, Lee EB. Novel VCP activator reverses multisystem proteinopathy nuclear proteostasis defects and enhances TDP-43 aggregate clearance. Biorxiv : the Preprint Server For Biology. PMID 36993559 DOI: 10.1101/2023.03.15.532082 |
0.701 |
|
2023 |
Giannini LAA, Ohm DT, Rozemuller AJM, Dratch L, Suh E, van Deerlin VM, Trojanowski JQ, Lee EB, van Swieten JC, Grossman M, Seelaar H, Irwin DJ. Correction to: Isoform-specific patterns of tau burden and neuronal degeneration in MAPT-associated frontotemporal lobar degeneration. Acta Neuropathologica. PMID 36930297 DOI: 10.1007/s00401-023-02556-2 |
0.782 |
|
2023 |
Neel DV, Basu H, Gunner G, Bergstresser MD, Giadone RM, Chung H, Miao R, Chou V, Brody E, Jiang X, Lee E, Watts ME, Marques C, Held A, Wainger B, et al. Gasdermin-E mediates mitochondrial damage in axons and neurodegeneration. Neuron. PMID 36917977 DOI: 10.1016/j.neuron.2023.02.019 |
0.53 |
|
2023 |
Tropea TF, Albuja I, Cousins KAQ, Irwin DJ, Lee EB, Chen-Plotkin AS. Concomitant Alzheimer's Disease Pathology in Parkinson's Disease Dementia. Annals of Neurology. PMID 36892304 DOI: 10.1002/ana.26635 |
0.625 |
|
2023 |
Robinson JL, Xie SX, Baer DR, Suh E, Van Deerlin VM, Loh NJ, Irwin D, McMillan CT, Wolk D, Chen-Plotkin A, Weintraub D, Schuck T, Lee VM, Trojanowski JQ, Lee EB. Pathological combinations in neurodegenerative disease are heterogeneous and disease-associated. Brain : a Journal of Neurology. PMID 36864661 DOI: 10.1093/brain/awad059 |
0.772 |
|
2023 |
Kim BJ, Grossman M, Aleman TS, Song D, Cousins KAQ, McMillan CT, Saludades A, Yu Y, Lee EB, Wolk D, Van Deerlin VM, Shaw LM, Ying GS, Irwin DJ. Retinal photoreceptor layer thickness has disease specificity and distinguishes predicted FTLD-Tau from biomarker-determined Alzheimer's disease. Neurobiology of Aging. 125: 74-82. PMID 36857870 DOI: 10.1016/j.neurobiolaging.2023.01.015 |
0.345 |
|
2023 |
Lyu X, Duong MT, Xie L, de Flores R, Richardson H, Hwang G, Wisse LEM, DiCalogero M, McMillan CT, Robinson JL, Xie SX, Grossman M, Lee EB, Irwin DJ, Dickerson BC, et al. Tau-Neurodegeneration reveals vulnerability and resilience to comorbidities in Alzheimer's continuum. Medrxiv : the Preprint Server For Health Sciences. PMID 36824762 DOI: 10.1101/2023.02.12.23285594 |
0.629 |
|
2023 |
Young AL, Vogel JW, Robinson JL, McMillan CT, Ossenkoppele R, Wolk DA, Irwin DJ, Elman L, Grossman M, Lee VM, Lee EB, Hansson O. Data-driven neuropathological staging and subtyping of TDP-43 proteinopathies. Medrxiv : the Preprint Server For Health Sciences. PMID 36778217 DOI: 10.1101/2023.01.31.23285242 |
0.57 |
|
2022 |
Robinson JL, Richardson H, Xie SX, Alfaro B, Loh N, Lee VM, Lee EB, Trojanowski JQ. Cerebrovascular disease lesions are additive and tied to vascular risk factors and cognitive impairment. Free Neuropathology. 3. PMID 37250748 DOI: 10.17879/freeneuropathology-2022-3792 |
0.671 |
|
2022 |
Tropea TF, Waligorska T, Xie SX, Nasrallah IM, Cousins KAQ, Trojanowski JQ, Grossman M, Irwin DJ, Weintraub D, Lee EB, Wolk DA, Chen-Plotkin AS, Shaw LM. Plasma phosphorylated tau181 predicts cognitive and functional decline. Annals of Clinical and Translational Neurology. PMID 36518085 DOI: 10.1002/acn3.51695 |
0.771 |
|
2022 |
Nelson PT, Lee EB, Cykowski MD, Alafuzoff I, Arfanakis K, Attems J, Brayne C, Corrada MM, Dugger BN, Flanagan ME, Ghetti B, Grinberg LT, Grossman M, Grothe MJ, Halliday GM, et al. LATE-NC staging in routine neuropathologic diagnosis: an update. Acta Neuropathologica. PMID 36512061 DOI: 10.1007/s00401-022-02524-2 |
0.488 |
|
2022 |
Olm CA, Burke SE, Peterson C, Lee EB, Trojanowski JQ, Massimo L, Irwin DJ, Grossman M, Gee JC. Event-based modeling of T1-weighted MRI is related to pathology in frontotemporal lobar degeneration due to tau and TDP. Neuroimage. Clinical. 37: 103285. PMID 36508888 DOI: 10.1016/j.nicl.2022.103285 |
0.528 |
|
2022 |
Sadaghiani S, Trotman W, Lim SA, Chung E, Ittyerah R, Ravikumar S, Khandelwal P, Prabhakaran K, Lavery ML, Ohm DT, Gabrielyan M, Das SR, Schuck T, Capp N, Peterson CS, ... ... Lee EB, et al. Associations of phosphorylated tau pathology with whole-hemisphere ex vivo morphometry in 7 tesla MRI. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36464907 DOI: 10.1002/alz.12884 |
0.781 |
|
2022 |
Uemura MT, Suh ER, Robinson JL, Brunden KR, Grossman M, Irwin DJ, Lee VM, Trojanowski JQ, Lee EB, Van Deerlin VM. Abundant co-pathologies of polyglucosan bodies, frontotemporal lobar degeneration with TDP-43 inclusions, and ageing-related tau astrogliopathy in a family with a GBE1 mutation. Neuropathology and Applied Neurobiology. e12865. PMID 36456471 DOI: 10.1111/nan.12865 |
0.665 |
|
2022 |
Coughlin DG, Hiniker A, Peterson C, Kim Y, Arezoumandan S, Giannini L, Pizzo D, Weintraub D, Siderowf A, Litvan I, Rissman RA, Galasko D, Hansen L, Trojanowski JQ, Lee E, et al. Digital Histological Study of Neocortical Grey and White Matter Tau Burden Across Tauopathies. Journal of Neuropathology and Experimental Neurology. PMID 36269086 DOI: 10.1093/jnen/nlac094 |
0.568 |
|
2022 |
Cousins KAQ, Shaw LM, Chen-Plotkin A, Wolk DA, Van Deerlin VM, Lee EB, McMillan CT, Grossman M, Irwin DJ. Distinguishing Frontotemporal Lobar Degeneration Tau From TDP-43 Using Plasma Biomarkers. Jama Neurology. PMID 36215050 DOI: 10.1001/jamaneurol.2022.3265 |
0.619 |
|
2022 |
Kim B, Suh E, Nguyen AT, Prokop S, Mikytuck B, Olatunji OA, Robinson JL, Grossman M, Phillips JS, Irwin DJ, Mechanic-Hamilton D, Wolk DA, Trojanowski JQ, McMillan CT, Van Deerlin VM, ... Lee EB, et al. TREM2 risk variants are associated with atypical Alzheimer's disease. Acta Neuropathologica. PMID 36112222 DOI: 10.1007/s00401-022-02495-4 |
0.835 |
|
2022 |
Giannini LAA, Ohm DT, Rozemuller AJM, Dratch L, Suh E, van Deerlin VM, Trojanowski JQ, Lee EB, van Swieten JC, Grossman M, Seelaar H, Irwin DJ. Isoform-specific patterns of tau burden and neuronal degeneration in MAPT-associated frontotemporal lobar degeneration. Acta Neuropathologica. PMID 36066634 DOI: 10.1007/s00401-022-02487-4 |
0.77 |
|
2022 |
Quilico Cousins KA, Arezoumandan S, Shellikeri S, Ohm D, Shaw LM, Grossman M, Wolk D, McMillan CT, Chen-Plotkin A, Lee E, Trojanowski JQ, Zetterberg H, Blennow K, Irwin DJ. CSF Biomarkers of Alzheimer Disease in Patients With Concomitant α-Synuclein Pathology. Neurology. PMID 36041863 DOI: 10.1212/WNL.0000000000201202 |
0.831 |
|
2022 |
Hopfner F, Tietz AK, Ruf VC, Ross OA, Koga S, Dickson D, Aguzzi A, Attems J, Beach T, Beller A, Cheshire WP, van Deerlin V, Desplats P, Deuschl G, Duyckaerts C, ... ... Lee EB, et al. Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 35997131 DOI: 10.1002/mds.29164 |
0.527 |
|
2022 |
Shellikeri S, Cho S, Cousins KAQ, Liberman M, Howard E, Balganorth Y, Weintraub D, Spindler M, Deik A, Lee EB, Trojanowski JQ, Irwin D, Wolk D, Grossman M, Nevler N. Natural speech markers of Alzheimer's disease co-pathology in Lewy body dementias. Parkinsonism & Related Disorders. 102: 94-100. PMID 35985146 DOI: 10.1016/j.parkreldis.2022.07.023 |
0.585 |
|
2022 |
Diaz-Ortiz ME, Seo Y, Posavi M, Carceles Cordon M, Clark E, Jain N, Charan R, Gallagher MD, Unger TL, Amari N, Skrinak RT, Davila-Rivera R, Brody EM, Han N, Zack R, ... ... Lee EB, et al. GPNMB confers risk for Parkinson's disease through interaction with α-synuclein. Science (New York, N.Y.). 377: eabk0637. PMID 35981040 DOI: 10.1126/science.abk0637 |
0.537 |
|
2022 |
Roemer SF, Grinberg LT, Crary JF, Seeley WW, McKee AC, Kovacs GG, Beach TG, Duyckaerts C, Ferrer IA, Gelpi E, Lee EB, Revesz T, White CL, Yoshida M, Pereira FL, et al. Rainwater Charitable Foundation criteria for the neuropathologic diagnosis progressive supranuclear palsy. Acta Neuropathologica. PMID 35947184 DOI: 10.1007/s00401-022-02479-4 |
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2022 |
Cousins KAQ, Shaw LM, Shellikeri S, Dratch L, Rosario L, Elman LB, Quinn C, Amado DA, Wolk DA, Tropea TF, Chen-Plotkin A, Irwin DJ, Grossman M, Lee EB, Trojanowski JQ, et al. Elevated plasma phosphorylated tau 181 in amyotrophic lateral sclerosis. Annals of Neurology. PMID 35877814 DOI: 10.1002/ana.26462 |
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2022 |
Arezoumandan S, Xie SX, Cousins KAQ, Mechanic-Hamilton DJ, Peterson CS, Huang CY, Ohm DT, Ittyerah R, McMillan CT, Wolk DA, Yushkevich P, Trojanowski JQ, Lee EB, Grossman M, Phillips JS, et al. Regional distribution and maturation of tau pathology among phenotypic variants of Alzheimer's disease. Acta Neuropathologica. PMID 35871112 DOI: 10.1007/s00401-022-02472-x |
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2022 |
Walker IM, Cousins KA, Siderowf A, Duda JE, Morley JF, Dahodwala N, Tropea T, Vaishnavi S, Wolk DA, Chen-Plotkin AS, Shaw LM, Lee EB, Trojanowski JQ, Grossman M, Weintraub D, et al. Non-tremor motor dysfunction in Lewy body dementias is associated with AD biomarkers. Parkinsonism & Related Disorders. 100: 33-36. PMID 35700626 DOI: 10.1016/j.parkreldis.2022.05.022 |
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2022 |
Coughlin DG, Coslett HB, Peterson C, Phillips JS, McMillan C, Lee EB, Trojanowski JQ, Grossman M, Irwin DJ. Lateralized and pathology in a case of Lewy body disease with corticobasal syndrome. Alzheimer's & Dementia (New York, N. Y.). 8: e12294. PMID 35592691 DOI: 10.1002/trc2.12294 |
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2022 |
Ameen-Ali KE, Bretzin A, Lee EB, Folkerth R, Hazrati LN, Iacono D, Keene CD, Kofler J, Kovacs GG, Nolan A, Perl DP, Priemer DS, Smith DH, Wiebe DJ, Stewart W. Detection of astrocytic tau pathology facilitates recognition of chronic traumatic encephalopathy neuropathologic change. Acta Neuropathologica Communications. 10: 50. PMID 35410438 DOI: 10.1186/s40478-022-01353-4 |
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2022 |
Cervantes González A, Irwin DJ, Alcolea D, McMillan CT, Chen-Plotkin A, Wolk D, Sirisi S, Dols-Icardo O, Querol-Vilaseca M, Illán-Gala I, Santos-Santos MA, Fortea J, Lee EB, Trojanowski JQ, Grossman M, et al. Multimarker synaptic protein cerebrospinal fluid panels reflect TDP-43 pathology and cognitive performance in a pathological cohort of frontotemporal lobar degeneration. Molecular Neurodegeneration. 17: 29. PMID 35395770 DOI: 10.1186/s13024-022-00534-y |
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2022 |
Burke SE, Phillips JS, Olm CA, Peterson CS, Cook PA, Gee JC, Lee EB, Trojanowski JQ, Massimo L, Irwin DJ, Grossman M. Phases of volume loss in patients with known frontotemporal lobar degeneration spectrum pathology. Neurobiology of Aging. 113: 95-107. PMID 35325815 DOI: 10.1016/j.neurobiolaging.2022.02.007 |
0.53 |
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2022 |
Chen M, Ohm DT, Phillips JS, McMillan CT, Capp N, Peterson C, Xie E, Wolk DA, Trojanowski JQ, Lee EB, Gee J, Grossman M, Irwin DJ. Divergent Histopathological Networks of Frontotemporal Degeneration Proteinopathy Subytpes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 35318284 DOI: 10.1523/JNEUROSCI.2061-21.2022 |
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2022 |
Franzmeier N, Brendel M, Beyer L, Slemann L, Kovacs GG, Arzberger T, Kurz C, Respondek G, Lukic MJ, Biel D, Rubinski A, Frontzkowski L, Hummel S, Müller A, Finze A, ... ... Lee EB, et al. Tau deposition patterns are associated with functional connectivity in primary tauopathies. Nature Communications. 13: 1362. PMID 35292638 DOI: 10.1038/s41467-022-28896-3 |
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2022 |
Feng T, Luan L, Katz II, Ullah M, Van Deerlin VM, Trojanowski JQ, Lee EB, Hu F. TMEM106B deficiency impairs cerebellar myelination and synaptic integrity with Purkinje cell loss. Acta Neuropathologica Communications. 10: 33. PMID 35287730 DOI: 10.1186/s40478-022-01334-7 |
0.483 |
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2022 |
Ohm DT, Cousins KAQ, Xie SX, Peterson C, McMillan CT, Massimo L, Raskovsky K, Wolk DA, Van Deerlin VM, Elman L, Spindler M, Deik A, Trojanowski JQ, Lee EB, Grossman M, et al. Signature laminar distributions of pathology in frontotemporal lobar degeneration. Acta Neuropathologica. PMID 34997851 DOI: 10.1007/s00401-021-02402-3 |
0.785 |
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2021 |
Steinkellner T, Conrad WS, Kovacs I, Rissman RA, Lee EB, Trojanowski JQ, Freyberg Z, Roy S, Luk KC, Lee VM, Hnasko TS. Dopamine neurons exhibit emergent glutamatergic identity in Parkinson's disease. Brain : a Journal of Neurology. PMID 35258081 DOI: 10.1093/brain/awab373 |
0.743 |
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2021 |
Tisdall MD, Ohm DT, Lobrovich R, Das SR, Mizsei G, Prabhakaran K, Ittyerah R, Lim S, McMillan CT, Wolk DA, Gee J, Trojanowski JQ, Lee EB, Detre JA, Yushkevich P, et al. Ex vivo MRI and histopathology detect novel iron-rich cortical inflammation in frontotemporal lobar degeneration with tau versus TDP-43 pathology. Neuroimage. Clinical. 33: 102913. PMID 34952351 DOI: 10.1016/j.nicl.2021.102913 |
0.795 |
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2021 |
Uemura MT, Robinson JL, Cousins KAQ, Tropea TF, Kargilis DC, McBride JD, Suh E, Xie SX, Xu Y, Porta S, Uemura N, Van Deerlin VM, Wolk DA, Irwin DJ, Brunden KR, ... ... Lee EB, et al. Distinct characteristics of limbic-predominant age-related TDP-43 encephalopathy in Lewy body disease. Acta Neuropathologica. PMID 34854996 DOI: 10.1007/s00401-021-02383-3 |
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2021 |
Kim BJ, Lee V, Lee EB, Saludades A, Trojanowski JQ, Dunaief JL, Grossman M, Irwin DJ. Retina tissue validation of optical coherence tomography determined outer nuclear layer loss in FTLD-tau. Acta Neuropathologica Communications. 9: 184. PMID 34794500 DOI: 10.1186/s40478-021-01290-8 |
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2021 |
Farrell K, Kim S, Han N, Iida MA, Gonzalez EM, Otero-Garcia M, Walker JM, Richardson TE, Renton AE, Andrews SJ, Fulton-Howard B, Humphrey J, Vialle RA, Bowles KR, de Paiva Lopes K, ... ... Lee EB, et al. Genome-wide association study and functional validation implicates JADE1 in tauopathy. Acta Neuropathologica. PMID 34719765 DOI: 10.1007/s00401-021-02379-z |
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2021 |
Ravikumar S, Wisse LEM, Lim S, Ittyerah R, Xie L, Bedard ML, Das SR, Lee EB, Tisdall MD, Prabhakaran K, Lane J, Detre JA, Mizsei G, Trojanowski JQ, Robinson JL, et al. Ex vivo MRI atlas of the human medial temporal lobe: characterizing neurodegeneration due to tau pathology. Acta Neuropathologica Communications. 9: 173. PMID 34689831 DOI: 10.1186/s40478-021-01275-7 |
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2021 |
Cousins KAQ, Bove J, Giannini LAA, Kinney NG, Balgenorth YR, Rascovsky K, Lee EB, Trojanowski JQ, Grossman M, Irwin DJ. Longitudinal naming and repetition relates to AD pathology and burden in autopsy-confirmed primary progressive aphasia. Alzheimer's & Dementia (New York, N. Y.). 7: e12188. PMID 34368417 DOI: 10.1002/trc2.12188 |
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2021 |
Iida MA, Farrell K, Walker JM, Richardson TE, Marx GA, Bryce CH, Purohit D, Ayalon G, Beach TG, Bigio EH, Cortes EP, Gearing M, Haroutunian V, McMillan CT, Lee EB, et al. Predictors of cognitive impairment in primary age-related tauopathy: an autopsy study. Acta Neuropathologica Communications. 9: 134. PMID 34353357 DOI: 10.1186/s40478-021-01233-3 |
0.677 |
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2021 |
Ho WY, Chang JC, Lim K, Cazenave-Gassiot A, Nguyen AT, Foo JC, Muralidharan S, Viera-Ortiz A, Ong SJM, Hor JH, Agrawal I, Hoon S, Arogundade OA, Rodriguez MJ, Lim SM, ... ... Lee EB, et al. TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination. The Journal of Cell Biology. 220. PMID 34347016 DOI: 10.1083/jcb.201910213 |
0.637 |
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2021 |
Yushkevich PA, López MM, Martin MMIO, Ittyerah R, Lim S, Ravikumar S, Bedard ML, Pickup S, Liu W, Wang J, Hung LY, Lasserve J, Vergnet N, Xie L, Dong M, ... ... Lee EB, et al. Three-dimensional mapping of neurofibrillary tangle burden in the human medial temporal lobe. Brain : a Journal of Neurology. PMID 34259858 DOI: 10.1093/brain/awab262 |
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2021 |
Mao F, Robinson JL, Unger T, Posavi M, Amado DA, Elman L, Grossman M, Wolk DA, Lee EB, Van Deerlin VM, Porta S, Lee VMY, Trojanowski JQ, Chen-Plotkin AS. TMEM106B modifies TDP-43 pathology in human ALS brain and cell-based models of TDP-43 proteinopathy. Acta Neuropathologica. PMID 34152475 DOI: 10.1007/s00401-021-02330-2 |
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2021 |
Lin YC, Kumar MS, Ramesh N, Anderson EN, Nguyen AT, Kim B, Cheung S, McDonough JA, Skarnes WC, Lopez-Gonzalez R, Landers JE, Fawzi NL, Mackenzie IRA, Lee EB, Nickerson JA, et al. Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway. Nature Neuroscience. PMID 34059832 DOI: 10.1038/s41593-021-00859-9 |
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2021 |
Porta S, Xu Y, Lehr T, Zhang B, Meymand E, Olufemi M, Stieber A, Lee EB, Trojanowski JQ, Lee VM. Distinct Brain-derived TDP-43 Strains from FTLD-TDP Subtypes Induce Diverse Morphological TDP-43 Aggregates and Spreading Patterns in vitro and in vivo. Neuropathology and Applied Neurobiology. PMID 33971027 DOI: 10.1111/nan.12732 |
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2021 |
Kim B, Mikytuck B, Suh E, Gibbons GS, Van Deerlin VM, Vaishnavi SN, Spindler MA, Massimo L, Grossman M, Trojanowski JQ, Irwin DJ, Lee EB. Tau immunotherapy is associated with glial responses in FTLD-tau. Acta Neuropathologica. PMID 33950293 DOI: 10.1007/s00401-021-02318-y |
0.577 |
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2021 |
Zhang JV, Irwin DJ, Blennow K, Zetterberg H, Lee EB, Shaw LM, Rascovsky K, Massimo L, McMillan CT, Chen-Plotkin A, Elman L, Lee VM, McCluskey L, Toledo JB, Weintraub D, et al. Neurofilament Light Chain Related to Longitudinal Decline in Frontotemporal Lobar Degeneration. Neurology. Clinical Practice. 11: 105-116. PMID 33842063 DOI: 10.1212/CPJ.0000000000000959 |
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2021 |
Soares AC, Ferreira A, Mariën J, Delay C, Lee E, Trojanowski JQ, Moechars D, Annaert W, De Muynck L. PIKfyve activity is required for lysosomal trafficking of tau aggregates and tau seeding. The Journal of Biological Chemistry. 100636. PMID 33831417 DOI: 10.1016/j.jbc.2021.100636 |
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2021 |
Smith DH, Dollé JP, Ameen-Ali KE, Bretzin A, Cortes E, Crary JF, Dams-O'Connor K, Diaz-Arrastia R, Edlow BL, Folkerth R, Hazrati LN, Hinds SR, Iacono D, Johnson VE, Keene CD, ... ... Lee EB, et al. COllaborative Neuropathology NEtwork Characterizing ouTcomes of TBI (CONNECT-TBI). Acta Neuropathologica Communications. 9: 32. PMID 33648593 DOI: 10.1186/s40478-021-01122-9 |
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2021 |
Giannini LAA, Peterson C, Ohm D, Xie SX, McMillan CT, Raskovsky K, Massimo L, Suh E, Van Deerlin VM, Wolk DA, Trojanowski JQ, Lee EB, Grossman M, Irwin DJ. Frontotemporal lobar degeneration proteinopathies have disparate microscopic patterns of white and grey matter pathology. Acta Neuropathologica Communications. 9: 30. PMID 33622418 DOI: 10.1186/s40478-021-01129-2 |
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2021 |
Nasrallah MP, Mourelatos Z, Lee EB. Neuropathology associated with SARS-CoV-2 infection. Lancet (London, England). 397: 277. PMID 33485446 DOI: 10.1016/S0140-6736(21)00096-9 |
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2021 |
Attems J, Toledo JB, Walker L, Gelpi E, Gentleman S, Halliday G, Hortobagyi T, Jellinger K, Kovacs GG, Lee EB, Love S, McAleese KE, Nelson PT, Neumann M, Parkkinen L, et al. Neuropathological consensus criteria for the evaluation of Lewy pathology in post-mortem brains: a multi-centre study. Acta Neuropathologica. PMID 33399945 DOI: 10.1007/s00401-020-02255-2 |
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2020 |
Robinson JL, Richardson H, Xie SX, Suh E, Van Deerlin VM, Alfaro B, Loh N, Porras-Paniagua M, Nirschl JJ, Wolk D, Lee VM, Lee EB, Trojanowski JQ. The development and convergence of co-pathologies in Alzheimer's disease. Brain : a Journal of Neurology. PMID 33449993 DOI: 10.1093/brain/awaa438 |
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2020 |
Arena JD, Johnson VE, Lee EB, Gibbons GS, Smith DH, Trojanowski JQ, Stewart W. Astroglial tau pathology alone preferentially concentrates at sulcal depths in chronic traumatic encephalopathy neuropathologic change. Brain Communications. 2: fcaa210. PMID 33426528 DOI: 10.1093/braincomms/fcaa210 |
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2020 |
Walker JM, Richardson TE, Farrell K, Iida MA, Foong C, Shang P, Attems J, Ayalon G, Beach TG, Bigio EH, Budson A, Cairns NJ, Corrada M, Cortes E, Dickson DW, ... ... Lee EB, et al. Early Selective Vulnerability of the CA2 Hippocampal Subfield in Primary Age-Related Tauopathy. Journal of Neuropathology and Experimental Neurology. PMID 33367843 DOI: 10.1093/jnen/nlaa153 |
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2020 |
Placek K, Benatar M, Wuu J, Rampersaud E, Hennessy L, Van Deerlin VM, Grossman M, Irwin DJ, Elman L, McCluskey L, Quinn C, Granit V, Statland JM, Burns TM, Ravits J, ... ... Lee EB, et al. Machine learning suggests polygenic risk for cognitive dysfunction in amyotrophic lateral sclerosis. Embo Molecular Medicine. e12595. PMID 33270986 DOI: 10.15252/emmm.202012595 |
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2020 |
Cousins KAQ, Phillips JS, Irwin DJ, Lee EB, Wolk DA, Shaw LM, Zetterberg H, Blennow K, Burke SE, Kinney NG, Gibbons GS, McMillan CT, Trojanowski JQ, Grossman M. ATN incorporating cerebrospinal fluid neurofilament light chain detects frontotemporal lobar degeneration. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33226735 DOI: 10.1002/alz.12233 |
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2020 |
Spotorno N, Coughlin DG, Olm CA, Wolk D, Vaishnavi SN, Shaw LM, Dahodwala N, Morley JF, Duda JE, Deik AF, Spindler MA, Chen-Plotkin A, Lee EB, Trojanowski JQ, McMillan CT, et al. Tau pathology associates with in vivo cortical thinning in Lewy body disorders. Annals of Clinical and Translational Neurology. PMID 33108692 DOI: 10.1002/acn3.51183 |
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2020 |
Darwich NF, Phan JM, Kim B, Suh E, Papatriantafyllou JD, Changolkar L, Nguyen AT, O'Rourke CM, He Z, Porta S, Gibbons GS, Luk KC, Papageorgiou SG, Grossman M, Massimo L, ... ... Lee EB, et al. Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau. Science (New York, N.Y.). PMID 33004675 DOI: 10.1126/science.aay8826 |
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2020 |
Coughlin DG, Phillips JS, Roll E, Peterson C, Lobrovich R, Rascovsky K, Ungrady M, Wolk DA, Das S, Weintraub D, Lee EB, Trojanowski JQ, Shaw LM, Vaishnavi S, Siderowf A, et al. Multimodal in vivo and postmortem assessments of tau in Lewy body disorders. Neurobiology of Aging. 96: 137-147. PMID 33002767 DOI: 10.1016/J.Neurobiolaging.2020.08.003 |
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2020 |
Coughlin DG, Ittyerah R, Peterson C, Phillips JS, Miller S, Rascovsky K, Weintraub DA, Siderowf AD, Duda JE, Hurtig HI, Wolk DA, McMillan C, Yushkevich PA, Grossman M, Lee EB, et al. Hippocampal Subfield Pathologic Burden in Lewy Body Diseases versus Alzheimer's Disease. Neuropathology and Applied Neurobiology. PMID 32892355 DOI: 10.1111/Nan.12659 |
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2020 |
Nguyen AT, Wang K, Hu G, Wang X, Miao Z, Azevedo JA, Suh E, Van Deerlin VM, Choi D, Roeder K, Li M, Lee EB. APOE and TREM2 regulate amyloid-responsive microglia in Alzheimer's disease. Acta Neuropathologica. PMID 32840654 DOI: 10.1007/S00401-020-02200-3 |
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2020 |
Robinson JL, Porta S, Garrett FG, Zhang P, Xie SX, Suh E, Van Deerlin VM, Abner EL, Jicha GA, Barber JM, Lee VM, Lee EB, Trojanowski JQ, Nelson PT. Limbic-predominant age-related TDP-43 encephalopathy differs from frontotemporal lobar degeneration. Brain : a Journal of Neurology. PMID 32830216 DOI: 10.1093/Brain/Awaa219 |
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2020 |
Ohm DT, Peterson C, Lobrovich R, Cousins KAQ, Gibbons GS, McMillan CT, Wolk DA, Van Deerlin V, Elman L, Spindler M, Deik A, Siderowf A, Trojanowski JQ, Lee EB, Grossman M, et al. Degeneration of the locus coeruleus is a common feature of tauopathies and distinct from TDP-43 proteinopathies in the frontotemporal lobar degeneration spectrum. Acta Neuropathologica. PMID 32804255 DOI: 10.1007/S00401-020-02210-1 |
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2020 |
Katsumata Y, Abner EL, Karanth S, Teylan MA, Mock CN, Cykowski MD, Lee EB, Boehme KL, Mukherjee S, Kauwe JSK, Kryscio RJ, Schmitt FA, Fardo DW, Nelson PT. Distinct clinicopathologic clusters of persons with TDP-43 proteinopathy. Acta Neuropathologica. PMID 32797255 DOI: 10.1007/S00401-020-02211-0 |
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2020 |
Dai DL, Tropea TF, Robinson JL, Suh E, Hurtig H, Weintraub D, Van Deerlin V, Lee EB, Trojanowski JQ, Chen-Plotkin AS. ADNC-RS, a clinical-genetic risk score, predicts Alzheimer's pathology in autopsy-confirmed Parkinson's disease and Dementia with Lewy bodies. Acta Neuropathologica. PMID 32749525 DOI: 10.1007/S00401-020-02199-7 |
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2020 |
Cornblath EJ, Robinson JL, Irwin DJ, Lee EB, Lee VM, Trojanowski JQ, Bassett DS. Defining and predicting transdiagnostic categories of neurodegenerative disease. Nature Biomedical Engineering. PMID 32747831 DOI: 10.1038/S41551-020-0593-Y |
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2020 |
Cousins KAQ, Irwin DJ, Wolk DA, Lee EB, Shaw LMJ, Trojanowski JQ, Da Re F, Gibbons GS, Grossman M, Phillips JS. ATN status in amnestic and non-amnestic Alzheimer's disease and frontotemporal lobar degeneration. Brain : a Journal of Neurology. PMID 32666090 DOI: 10.1093/Brain/Awaa165 |
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2020 |
Arena JD, Smith DH, Lee EB, Gibbons GS, Irwin DJ, Robinson JL, Lee VM, Trojanowski JQ, Stewart W, Johnson VE. Tau immunophenotypes in chronic traumatic encephalopathy recapitulate those of ageing and Alzheimer's disease. Brain : a Journal of Neurology. PMID 32390044 DOI: 10.1093/Brain/Awaa071 |
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2020 |
Kovacs GG, Lukic MJ, Irwin DJ, Arzberger T, Respondek G, Lee EB, Coughlin D, Giese A, Grossman M, Kurz C, McMillan CT, Gelpi E, Compta Y, van Swieten JC, Laat LD, et al. Distribution patterns of tau pathology in progressive supranuclear palsy. Acta Neuropathologica. PMID 32383020 DOI: 10.1007/S00401-020-02158-2 |
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2020 |
de Flores R, Wisse LEM, Das SR, Xie L, McMillan CT, Trojanowski JQ, Robinson JL, Grossman M, Lee E, Irwin DJ, Yushkevich PA, Wolk DA. Contribution of mixed pathology to medial temporal lobe atrophy in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32323446 DOI: 10.1002/Alz.12079 |
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2020 |
Johnson ECB, Dammer EB, Duong DM, Ping L, Zhou M, Yin L, Higginbotham LA, Guajardo A, White B, Troncoso JC, Thambisetty M, Montine TJ, Lee EB, Trojanowski JQ, Beach TG, et al. Large-scale proteomic analysis of Alzheimer's disease brain and cerebrospinal fluid reveals early changes in energy metabolism associated with microglia and astrocyte activation. Nature Medicine. PMID 32284590 DOI: 10.1038/S41591-020-0815-6 |
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2019 |
Robinson JL, Yan N, Caswell C, Xie SX, Suh E, Van Deerlin VM, Gibbons G, Irwin DJ, Grossman M, Lee EB, Lee VM, Miller B, Trojanowski JQ. Primary Tau Pathology, Not Copathology, Correlates With Clinical Symptoms in PSP and CBD. Journal of Neuropathology and Experimental Neurology. PMID 31999351 DOI: 10.1093/Jnen/Nlz141 |
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2019 |
Spotorno N, Hall S, Irwin DJ, Rumetshofer T, Acosta-Cabronero J, Deik AF, Spindler MA, Lee EB, Trojanowski JQ, van Westen D, Nilsson M, Grossman M, Nestor PJ, McMillan CT, Hansson O. Diffusion Tensor MRI to Distinguish Progressive Supranuclear Palsy from α-Synucleinopathies. Radiology. 190406. PMID 31617796 DOI: 10.1148/Radiol.2019190406 |
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2019 |
Caswell C, McMillan CT, Xie SX, Van Deerlin VM, Suh E, Lee EB, Trojanowski JQ, Lee VM, Irwin DJ, Grossman M, Massimo LM. Genetic predictors of survival in behavioral variant frontotemporal degeneration. Neurology. PMID 31537715 DOI: 10.1212/Wnl.0000000000008387 |
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2019 |
Giannini LAA, Xie SX, Peterson C, Zhou C, Lee EB, Wolk DA, Grossman M, Trojanowski JQ, McMillan CT, Irwin DJ. Empiric Methods to Account for Pre-analytical Variability in Digital Histopathology in Frontotemporal Lobar Degeneration. Frontiers in Neuroscience. 13: 682. PMID 31333403 DOI: 10.3389/Fnins.2019.00682 |
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2019 |
Cali CP, Patino M, Tai YK, Ho WY, McLean CA, Morris CM, Seeley WW, Miller BL, Gaig C, Vonsattel JPG, White CL, Roeber S, Kretzschmar H, Troncoso JC, Troakes C, ... ... Lee EB, et al. C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy. Acta Neuropathologica. PMID 31327044 DOI: 10.1007/S00401-019-02045-5 |
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2019 |
Lee EB, Kinch K, Johnson VE, Trojanowski JQ, Smith DH, Stewart W. Chronic traumatic encephalopathy is a common co-morbidity, but less frequent primary dementia in former soccer and rugby players. Acta Neuropathologica. PMID 31152201 DOI: 10.1007/S00401-019-02030-Y |
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2019 |
Phillips JS, Da Re F, Irwin DJ, McMillan CT, Vaishnavi SN, Xie SX, Lee EB, Cook PA, Gee JC, Shaw LM, Trojanowski JQ, Wolk DA, Grossman M. Longitudinal progression of grey matter atrophy in non-amnestic Alzheimer's disease. Brain : a Journal of Neurology. 142: 1701-1722. PMID 31135048 DOI: 10.1093/Brain/Awz091 |
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2019 |
Viaene AN, Lee EB, Rosenbaum JN, Nasrallah IM, Nasrallah MP. Histologic, immunohistochemical, and molecular features of pituicytomas and atypical pituicytomas. Acta Neuropathologica Communications. 7: 69. PMID 31046843 DOI: 10.1186/S40478-019-0722-6 |
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2019 |
Liu EY, Russ J, Cali CP, Phan JM, Amlie-Wolf A, Lee EB. Loss of Nuclear TDP-43 Is Associated with Decondensation of LINE Retrotransposons. Cell Reports. 27: 1409-1421.e6. PMID 31042469 DOI: 10.1016/J.Celrep.2019.04.003 |
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2019 |
Giannini LA, Xie SX, McMillan CT, Liang M, Williams A, Jester C, Rascovsky K, Wolk DA, Ash S, Lee EB, Trojanowski JQ, Grossman M, Irwin DJ. Divergent Patterns of TDP-43 and Tau Pathologies in Primary Progressive Aphasia. Annals of Neurology. PMID 30851133 DOI: 10.1002/Ana.25465 |
0.619 |
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2019 |
Stewart W, Allinson K, Al-Sarraj S, Bachmeier C, Barlow K, Belli A, Burns MP, Carson A, Crawford F, Dams-O'Connor K, Diaz-Arrastia R, Dixon CE, Edlow BL, Ferguson S, Fischl B, ... ... Lee EB, et al. Primum non nocere: a call for balance when reporting on CTE. The Lancet. Neurology. 18: 231-233. PMID 30784550 DOI: 10.1016/S1474-4422(19)30020-1 |
0.448 |
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2019 |
Pottier C, Ren Y, Perkerson RB, Baker M, Jenkins GD, van Blitterswijk M, DeJesus-Hernandez M, van Rooij JGJ, Murray ME, Christopher E, McDonnell SK, Fogarty Z, Batzler A, Tian S, Vicente CT, ... ... Lee EB, et al. Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD. Acta Neuropathologica. PMID 30739198 DOI: 10.1007/S00401-019-01962-9 |
0.521 |
|
2019 |
Darwich NF, Phan JM, Suh ER, Toro C, Grossman M, Irwin D, McMillan CT, Aguirre GK, Van Deerlin VM, Lee EB. A HYPOMORPH MUTATION OF THE TAU DISAGGREGASE VCP IS ASSOCIATED WITH VACUOLAR TAUOPATHY Alzheimer's & Dementia. 15: P1603. DOI: 10.1016/J.Jalz.2019.09.071 |
0.335 |
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2018 |
Coughlin DG, Xie SX, Liang M, Williams A, Peterson C, Weintraub D, McMillan CT, Wolk DA, Akhtar RS, Hurtig H, Coslett HB, Hamilton R, Siderowf A, Duda JE, Rascovsky K, ... Lee EB, et al. Cognitive and Pathological Influences of Tau Pathology in Lewy Body Disorders. Annals of Neurology. PMID 30549331 DOI: 10.1002/Ana.25392 |
0.747 |
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2018 |
Placek K, Baer GM, Elman L, McCluskey L, Hennessy L, Ferraro PM, Lee EB, Lee VMY, Trojanowski JQ, Van Deerlin VM, Grossman M, Irwin DJ, McMillan CT. UNC13A polymorphism contributes to frontotemporal disease in sporadic amyotrophic lateral sclerosis. Neurobiology of Aging. 73: 190-199. PMID 30368160 DOI: 10.1016/J.Neurobiolaging.2018.09.031 |
0.539 |
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2018 |
Porta S, Xu Y, Restrepo CR, Kwong LK, Zhang B, Brown HJ, Lee EB, Trojanowski JQ, Lee VM. Patient-derived frontotemporal lobar degeneration brain extracts induce formation and spreading of TDP-43 pathology in vivo. Nature Communications. 9: 4220. PMID 30310141 DOI: 10.1038/S41467-018-06548-9 |
0.702 |
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2018 |
Alcolea D, Irwin DJ, Illán-Gala I, Muñoz L, Clarimón J, McMillan CT, Fortea J, Blesa R, Lee EB, Trojanowski JQ, Grossman M, Lleó A. Elevated YKL-40 and low sAPPβ:YKL-40 ratio in antemortem cerebrospinal fluid of patients with pathologically confirmed FTLD. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 30297518 DOI: 10.1136/Jnnp-2018-318993 |
0.557 |
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2018 |
Brettschneider J, Suh E, Robinson JL, Fang L, Lee EB, Irwin DJ, Grossman M, Van Deerlin VM, Lee VM, Trojanowski JQ. Converging Patterns of α-Synuclein Pathology in Multiple System Atrophy. Journal of Neuropathology and Experimental Neurology. PMID 30203094 DOI: 10.1093/Jnen/Nly080 |
0.695 |
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2018 |
McMillan CT, Lee EB, Jefferson-George K, Naj A, Van Deerlin VM, Trojanowski JQ, Wolk DA. Alzheimer's genetic risk is reduced in primary age-related tauopathy: a potential model of resistance? Annals of Clinical and Translational Neurology. 5: 927-934. PMID 30128317 DOI: 10.1002/Acn3.581 |
0.618 |
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2018 |
Kovacs GG, Xie SX, Robinson JL, Lee EB, Smith DH, Schuck T, Lee VM, Trojanowski JQ. Sequential stages and distribution patterns of aging-related tau astrogliopathy (ARTAG) in the human brain. Acta Neuropathologica Communications. 6: 50. PMID 29891013 DOI: 10.1186/S40478-018-0552-Y |
0.723 |
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2018 |
Robinson JL, Lee EB, Xie SX, Rennert L, Suh E, Bredenberg C, Caswell C, Van Deerlin VM, Yan N, Yousef A, Hurtig HI, Siderowf A, Grossman M, McMillan CT, Miller B, et al. Neurodegenerative disease concomitant proteinopathies are prevalent, age-related and APOE4-associated. Brain : a Journal of Neurology. PMID 29878075 DOI: 10.1093/Brain/Awy146 |
0.803 |
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2018 |
Pottier C, Zhou X, Perkerson RB, Baker M, Jenkins GD, Serie DJ, Ghidoni R, Benussi L, Binetti G, López de Munain A, Zulaica M, Moreno F, Le Ber I, Pasquier F, Hannequin D, ... ... Lee EB, et al. Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. The Lancet. Neurology. PMID 29724592 DOI: 10.1016/S1474-4422(18)30126-1 |
0.541 |
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2018 |
Shi M, Tang L, Toledo JB, Ginghina C, Wang H, Aro P, Jensen PH, Weintraub D, Chen-Plotkin AS, Irwin DJ, Grossman M, McCluskey L, Elman LB, Wolk DA, Lee EB, et al. Cerebrospinal fluid α-synuclein contributes to the differential diagnosis of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29604263 DOI: 10.1016/J.Jalz.2018.02.015 |
0.736 |
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2018 |
Lleó A, Irwin DJ, Illán-Gala I, McMillan CT, Wolk DA, Lee EB, Van Deerlin VM, Shaw LM, Trojanowski JQ, Grossman M. A 2-Step Cerebrospinal Algorithm for the Selection of Frontotemporal Lobar Degeneration Subtypes. Jama Neurology. PMID 29554190 DOI: 10.1001/Jamaneurol.2018.0118 |
0.63 |
|
2018 |
Lee EB. Integrated neurodegenerative disease autopsy diagnosis. Acta Neuropathologica. PMID 29502201 DOI: 10.1007/S00401-018-1827-X |
0.352 |
|
2018 |
Irwin DJ, Xie SX, Coughlin D, Nevler N, Akhtar RS, McMillan CT, Lee EB, Wolk DA, Weintraub D, Chen-Plotkin A, Duda JE, Spindler M, Siderowf A, Hurtig HI, Shaw LM, et al. CSF tau and amyloid-beta predict cerebral synucleinopathy in autopsied Lewy body disorders. Neurology. PMID 29467305 DOI: 10.1212/Wnl.0000000000005166 |
0.693 |
|
2018 |
Conlon EG, Fagegaltier D, Agius P, Davis-Porada J, Gregory J, Hubbard I, Kang K, Kim D, Phatnani H, Kwan J, Sareen D, Broach JR, Simmons Z, Arcila-Londono X, Lee EB, et al. Author response: Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism Elife. DOI: 10.7554/Elife.37754.025 |
0.322 |
|
2017 |
Wang L, Hubbard RA, Walker RL, Lee EB, Larson EB, Crane PK. Assessing robustness of hazard ratio estimates to outcome misclassification in longitudinal panel studies with application to Alzheimer's disease. Plos One. 12: e0190107. PMID 29272296 DOI: 10.1371/Journal.Pone.0190107 |
0.379 |
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2017 |
Irwin DJ, McMillan CT, Xie SX, Rascovsky K, Van Deerlin VM, Coslett HB, Hamilton R, Aguirre G, Lee EB, Lee VMY, Trojanowski JQ, Grossman M. Asymmetry of post-mortem neuropathology in behavioural-variant frontotemporal dementia. Brain : a Journal of Neurology. PMID 29228211 DOI: 10.1093/Brain/Awx319 |
0.6 |
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2017 |
Phillips JS, Da Re F, Dratch L, Xie SX, Irwin DJ, McMillan CT, Vaishnavi SN, Ferrarese C, Lee EB, Shaw LM, Trojanowski JQ, Wolk DA, Grossman M. Neocortical origin and progression of gray matter atrophy in nonamnestic Alzheimer's disease. Neurobiology of Aging. 63: 75-87. PMID 29223682 DOI: 10.1016/J.Neurobiolaging.2017.11.008 |
0.607 |
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2017 |
Yousef A, Robinson JL, Irwin DJ, Byrne MD, Kwong LK, Lee EB, Xu Y, Xie SX, Rennert L, Suh E, Van Deerlin VM, Grossman M, Lee VM, Trojanowski JQ. Neuron loss and degeneration in the progression of TDP-43 in frontotemporal lobar degeneration. Acta Neuropathologica Communications. 5: 68. PMID 28877758 DOI: 10.1186/S40478-017-0471-3 |
0.691 |
|
2017 |
Irwin DJ, Lleó A, Xie SX, McMillan CT, Wolk D, Lee EB, Van Deerlin VM, Shaw LM, Trojanowski JQ, Grossman M. Ante mortem CSF tau levels correlate with post mortem tau pathology in FTLD. Annals of Neurology. PMID 28719018 DOI: 10.1002/Ana.24996 |
0.627 |
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2017 |
Paolicelli RC, Jawaid A, Henstridge CM, Valeri A, Merlini M, Robinson JL, Lee EB, Rose J, Appel S, Lee VM, Trojanowski JQ, Spires-Jones T, Schulz PE, Rajendran L. TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss. Neuron. PMID 28669544 DOI: 10.1016/J.Neuron.2017.05.037 |
0.736 |
|
2017 |
Kovacs GG, Xie SX, Lee EB, Robinson JL, Caswell C, Irwin DJ, Toledo JB, Johnson VE, Smith DH, Alafuzoff I, Attems J, Bencze J, Bieniek KF, Bigio EH, Bodi I, et al. Multisite Assessment of Aging-Related Tau Astrogliopathy (ARTAG). Journal of Neuropathology and Experimental Neurology. PMID 28591867 DOI: 10.1093/Jnen/Nlx041 |
0.637 |
|
2017 |
Giannini LAA, Irwin DJ, McMillan CT, Ash S, Rascovsky K, Wolk DA, Van Deerlin VM, Lee EB, Trojanowski JQ, Grossman M. Clinical marker for Alzheimer disease pathology in logopenic primary progressive aphasia. Neurology. PMID 28515265 DOI: 10.1212/Wnl.0000000000004034 |
0.635 |
|
2017 |
Liu EY, Cali CP, Lee EB. RNA metabolism in neurodegenerative disease. Disease Models & Mechanisms. 10: 509-518. PMID 28468937 DOI: 10.1242/Dmm.028613 |
0.319 |
|
2017 |
Kovacs GG, Robinson JL, Xie SX, Lee EB, Grossman M, Wolk DA, Irwin DJ, Weintraub D, Kim CF, Schuck T, Yousef A, Wagner ST, Suh E, Van Deerlin VM, Lee VM, et al. Evaluating the Patterns of Aging-Related Tau Astrogliopathy Unravels Novel Insights Into Brain Aging and Neurodegenerative Diseases. Journal of Neuropathology and Experimental Neurology. PMID 28340083 DOI: 10.1093/Jnen/Nlx007 |
0.74 |
|
2017 |
Jefferson-George KS, Wolk DA, Lee EB, McMillan CT. Cognitive decline associated with pathological burden in primary age-related tauopathy. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28322204 DOI: 10.1016/J.Jalz.2017.01.028 |
0.398 |
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2017 |
Lee EB, Porta S, Michael Baer G, Xu Y, Suh E, Kwong LK, Elman L, Grossman M, Lee VM, Irwin DJ, Van Deerlin VM, Trojanowski JQ. Expansion of the classification of FTLD-TDP: distinct pathology associated with rapidly progressive frontotemporal degeneration. Acta Neuropathologica. PMID 28130640 DOI: 10.1007/S00401-017-1679-9 |
0.724 |
|
2017 |
Irwin DJ, Grossman M, Weintraub D, Hurtig HI, Duda JE, Xie SX, Lee EB, Van Deerlin VM, Lopez OL, Kofler JK, Nelson PT, Jicha GA, Woltjer R, Quinn JF, Kaye J, et al. Neuropathological and genetic correlates of survival and dementia onset in synucleinopathies: a retrospective analysis. The Lancet. Neurology. 16: 55-65. PMID 27979356 DOI: 10.1016/S1474-4422(16)30291-5 |
0.636 |
|
2017 |
Da Re F, Phillips JS, Dratch L, Ferrarese C, Irwin DJ, McMillan CT, Lee E, Shaw LM, Trojanowski JQ, Wolk DA, Grossman M. [P4-238]: AMNESTIC AND NON-AMNESTIC PHENOTYPES OF ALZHEIMER'S DISEASE: AN MRI-BASED PHASING ANALYSIS Alzheimer's & Dementia. 13: P1365-P1366. DOI: 10.1016/J.Jalz.2017.06.2106 |
0.572 |
|
2016 |
Spotorno N, McMillan CT, Irwin DJ, Clark R, Lee EB, Trojanowski JQ, Weintraub D, Grossman M. Decision-Making Deficits Associated with Amyloidosis in Lewy Body Disorders. Frontiers in Human Neuroscience. 10: 693. PMID 28123364 DOI: 10.3389/Fnhum.2016.00693 |
0.584 |
|
2016 |
Kovacs GG, Kwong LK, Grossman M, Irwin DJ, Lee EB, Robinson JL, Suh E, Van Deerlin VM, Lee VM, Trojanowski JQ. Tauopathy with hippocampal 4-repeat tau immunoreactive spherical inclusions: a report of three cases. Brain Pathology (Zurich, Switzerland). PMID 28019685 DOI: 10.1111/Bpa.12482 |
0.731 |
|
2016 |
McMillan CT, Irwin DJ, Nasrallah I, Phillips JS, Spindler M, Rascovsky K, Ternes K, Jester C, Wolk DA, Kwong LK, Lee VM, Lee EB, Trojanowski JQ, Grossman M. Multimodal evaluation demonstrates in vivo (18)F-AV-1451 uptake in autopsy-confirmed corticobasal degeneration. Acta Neuropathologica. PMID 27815633 DOI: 10.1007/S00401-016-1640-3 |
0.71 |
|
2016 |
Brettschneider J, Irwin DJ, Boluda S, Byrne MD, Fang L, Lee EB, Robinson JL, Suh E, Van Deerlin VM, Toledo JB, Grossman M, Hurtig H, Dengler R, Petri S, Lee VM, et al. Progression of alpha-synuclein pathology in multiple system atrophy of the cerebellar type. Neuropathology and Applied Neurobiology. PMID 27716988 DOI: 10.1111/Nan.12362 |
0.532 |
|
2016 |
Placek K, Massimo L, Olm C, Ternes K, Firn K, Van Deerlin V, Lee EB, Trojanowski JQ, Lee VM, Irwin D, Grossman M, McMillan CT. Cognitive reserve in frontotemporal degeneration: Neuroanatomic and neuropsychological evidence. Neurology. PMID 27683847 DOI: 10.1212/WNL.0000000000003250 |
0.643 |
|
2016 |
McMillan CT, Boyd C, Gross RG, Weinstein J, Firn K, Toledo JB, Rascovsky K, Shaw L, Wolk DA, Irwin DJ, Lee EB, Trojanowski JQ, Grossman M. Multimodal imaging evidence of pathology-mediated disease distribution in corticobasal syndrome. Neurology. PMID 27543644 DOI: 10.1212/Wnl.0000000000003119 |
0.543 |
|
2015 |
Toledo JB, Gopal P, Raible K, Irwin DJ, Brettschneider J, Sedor S, Waits K, Boluda S, Grossman M, Van Deerlin VM, Lee EB, Arnold SE, Duda JE, Hurtig H, Lee VM, et al. Pathological α-synuclein distribution in subjects with coincident Alzheimer's and Lewy body pathology. Acta Neuropathologica. PMID 26721587 DOI: 10.1007/S00401-015-1526-9 |
0.786 |
|
2015 |
Kovacs GG, Ferrer I, Grinberg LT, Alafuzoff I, Attems J, Budka H, Cairns NJ, Crary JF, Duyckaerts C, Ghetti B, Halliday GM, Ironside JW, Love S, Mackenzie IR, Munoz DG, ... ... Lee EB, et al. Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy. Acta Neuropathologica. PMID 26659578 DOI: 10.1007/S00401-015-1509-X |
0.751 |
|
2015 |
O'Rourke JG, Bogdanik L, Muhammad AK, Gendron TF, Kim KJ, Austin A, Cady J, Liu EY, Zarrow J, Grant S, Ho R, Bell S, Carmona S, Simpkinson M, Lall D, ... ... Lee EB, et al. C9orf72 BAC Transgenic Mice Display Typical Pathologic Features of ALS/FTD. Neuron. 88: 892-901. PMID 26637796 DOI: 10.1016/J.Neuron.2015.10.027 |
0.334 |
|
2015 |
Irwin DJ, Brettschneider J, McMillan CT, Cooper F, Olm C, Arnold SE, Van Deerlin VM, Seeley WW, Miller BL, Lee EB, Lee VM, Grossman M, Trojanowski JQ. Deep Clinical and Neuropathological Phenotyping of Pick's Disease. Annals of Neurology. PMID 26583316 DOI: 10.1002/Ana.24559 |
0.691 |
|
2015 |
Irwin DJ, Byrne MD, McMillan CT, Cooper F, Arnold SE, Lee EB, Van Deerlin VM, Xie SX, Lee VM, Grossman M, Trojanowski JQ. Semi-Automated Digital Image Analysis of Pick's Disease and TDP-3 Proteinopathy. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. PMID 26538548 DOI: 10.1369/0022155415614303 |
0.696 |
|
2015 |
Amlie-Wolf A, Ryvkin P, Tong R, Dragomir I, Suh E, Xu Y, Van Deerlin VM, Gregory BD, Kwong LK, Trojanowski JQ, Lee VM, Wang LS, Lee EB. Transcriptomic Changes Due to Cytoplasmic TDP-43 Expression Reveal Dysregulation of Histone Transcripts and Nuclear Chromatin. Plos One. 10: e0141836. PMID 26510133 DOI: 10.1371/Journal.Pone.0141836 |
0.656 |
|
2015 |
Montine TJ, Monsell SE, Beach TG, Bigio EH, Bu Y, Cairns NJ, Frosch M, Henriksen J, Kofler J, Kukull WA, Lee EB, Nelson PT, Schantz AM, Schneider JA, Sonnen JA, et al. Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26327235 DOI: 10.1016/J.Jalz.2015.07.492 |
0.687 |
|
2015 |
Robinson JL, Suh E, Wood EM, Lee EB, Coslett HB, Raible K, Lee VM, Trojanowski JQ, Van Deerlin VM. Common neuropathological features underlie distinct clinical presentations in three siblings with hereditary diffuse leukoencephalopathy with spheroids caused by CSF1R p.Arg782His. Acta Neuropathologica Communications. 3: 42. PMID 26141825 DOI: 10.1186/S40478-015-0219-X |
0.677 |
|
2015 |
Suh E, Lee EB, Neal D, Wood EM, Toledo JB, Rennert L, Irwin DJ, McMillan CT, Krock B, Elman LB, McCluskey LF, Grossman M, Xie SX, Trojanowski JQ, Van Deerlin VM. Semi-automated quantification of C9orf72 expansion size reveals inverse correlation between hexanucleotide repeat number and disease duration in frontotemporal degeneration. Acta Neuropathologica. PMID 26022924 DOI: 10.1007/S00401-015-1445-9 |
0.552 |
|
2015 |
Brettschneider J, Del Tredici K, Irwin DJ, Grossman M, Robinson JL, Toledo JB, Lee EB, Fang L, Van Deerlin VM, Ludolph AC, Lee VM, Braak H, Trojanowski JQ. Erratum to: Sequential distribution of pTDP-43 pathology in behavioral variant frontotemporal dementia (bvFTD). Acta Neuropathologica. 129: 929. PMID 25931052 DOI: 10.1007/S00401-015-1428-X |
0.681 |
|
2015 |
Irwin DJ, Cairns NJ, Grossman M, McMillan CT, Lee EB, Van Deerlin VM, Lee VM, Trojanowski JQ. Frontotemporal lobar degeneration: defining phenotypic diversity through personalized medicine. Acta Neuropathologica. 129: 469-91. PMID 25549971 DOI: 10.1007/S00401-014-1380-1 |
0.728 |
|
2015 |
Russ J, Liu EY, Wu K, Neal D, Suh E, Irwin DJ, McMillan CT, Harms MB, Cairns NJ, Wood EM, Xie SX, Elman L, McCluskey L, Grossman M, Van Deerlin VM, ... Lee EB, et al. Hypermethylation of repeat expanded C9orf72 is a clinical and molecular disease modifier. Acta Neuropathologica. 129: 39-52. PMID 25388784 DOI: 10.1007/S00401-014-1365-0 |
0.358 |
|
2014 |
McGurk L, Lee VM, Trojanowksi JQ, Van Deerlin VM, Lee EB, Bonini NM. Poly-A binding protein-1 localization to a subset of TDP-43 inclusions in amyotrophic lateral sclerosis occurs more frequently in patients harboring an expansion in C9orf72. Journal of Neuropathology and Experimental Neurology. 73: 837-45. PMID 25111021 DOI: 10.1097/Nen.0000000000000102 |
0.577 |
|
2014 |
Yarchoan M, Toledo JB, Lee EB, Arvanitakis Z, Kazi H, Han LY, Louneva N, Lee VM, Kim SF, Trojanowski JQ, Arnold SE. Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies. Acta Neuropathologica. 128: 679-89. PMID 25107476 DOI: 10.1007/S00401-014-1328-5 |
0.742 |
|
2014 |
Robinson JL, Molina-Porcel L, Corrada MM, Raible K, Lee EB, Lee VM, Kawas CH, Trojanowski JQ. Perforant path synaptic loss correlates with cognitive impairment and Alzheimer's disease in the oldest-old. Brain : a Journal of Neurology. 137: 2578-87. PMID 25012223 DOI: 10.1093/Brain/Awu190 |
0.702 |
|
2014 |
Boluda S, Toledo JB, Irwin DJ, Raible KM, Byrne MD, Lee EB, Lee VM, Trojanowski JQ. A comparison of Aβ amyloid pathology staging systems and correlation with clinical diagnosis. Acta Neuropathologica. 128: 543-50. PMID 24916271 DOI: 10.1007/S00401-014-1308-9 |
0.732 |
|
2014 |
Brettschneider J, Arai K, Del Tredici K, Toledo JB, Robinson JL, Lee EB, Kuwabara S, Shibuya K, Irwin DJ, Fang L, Van Deerlin VM, Elman L, McCluskey L, Ludolph AC, Lee VM, et al. TDP-43 pathology and neuronal loss in amyotrophic lateral sclerosis spinal cord. Acta Neuropathologica. 128: 423-37. PMID 24916269 DOI: 10.1007/S00401-014-1299-6 |
0.683 |
|
2014 |
Brettschneider J, Del Tredici K, Irwin DJ, Grossman M, Robinson JL, Toledo JB, Lee EB, Fang L, Van Deerlin VM, Ludolph AC, Lee VM, Braak H, Trojanowski JQ. Sequential distribution of pTDP-43 pathology in behavioral variant frontotemporal dementia (bvFTD). Acta Neuropathologica. 127: 423-39. PMID 24407427 DOI: 10.1007/S00401-013-1238-Y |
0.665 |
|
2014 |
Toledo JB, Van Deerlin VM, Lee EB, Suh E, Baek Y, Robinson JL, Xie SX, McBride J, Wood EM, Schuck T, Irwin DJ, Gross RG, Hurtig H, McCluskey L, Elman L, et al. A platform for discovery: The University of Pennsylvania Integrated Neurodegenerative Disease Biobank. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 477-84.e1. PMID 23978324 DOI: 10.1016/J.Jalz.2013.06.003 |
0.76 |
|
2013 |
Wood EM, Falcone D, Suh E, Irwin DJ, Chen-Plotkin AS, Lee EB, Xie SX, Van Deerlin VM, Grossman M. Development and validation of pedigree classification criteria for frontotemporal lobar degeneration. Jama Neurology. 70: 1411-7. PMID 24081456 DOI: 10.1001/Jamaneurol.2013.3956 |
0.575 |
|
2013 |
Lee EB, Russ J, Jung H, Elman LB, Chahine LM, Kremens D, Miller BL, Branch Coslett H, Trojanowski JQ, Van Deerlin VM, McCluskey LF. Topography of FUS pathology distinguishes late-onset BIBD from aFTLD-U. Acta Neuropathologica Communications. 1: 1-11. PMID 24027631 DOI: 10.1186/2051-5960-1-9 |
0.619 |
|
2013 |
Arnold SE, Toledo JB, Appleby DH, Xie SX, Wang LS, Baek Y, Wolk DA, Lee EB, Miller BL, Lee VM, Trojanowski JQ. Comparative survey of the topographical distribution of signature molecular lesions in major neurodegenerative diseases. The Journal of Comparative Neurology. 521: 4339-55. PMID 23881776 DOI: 10.1002/Cne.23430 |
0.723 |
|
2013 |
Brettschneider J, Del Tredici K, Toledo JB, Robinson JL, Irwin DJ, Grossman M, Suh E, Van Deerlin VM, Wood EM, Baek Y, Kwong L, Lee EB, Elman L, McCluskey L, Fang L, et al. Stages of pTDP-43 pathology in amyotrophic lateral sclerosis. Annals of Neurology. 74: 20-38. PMID 23686809 DOI: 10.1002/Ana.23937 |
0.648 |
|
2013 |
Toledo J, Arnold S, Brettschneider J, Lee E, Irwin D, Xie S, Grossman M, Monsell S, Kukull W, Trojanowski J. O2-10-02: Importance of coincident neurodegenerative diseases Alzheimer's & Dementia. 9: P334-P334. DOI: 10.1016/J.Jalz.2013.04.190 |
0.513 |
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2012 |
Yarchoan M, Xie SX, Kling MA, Toledo JB, Wolk DA, Lee EB, Van Deerlin V, Lee VM, Trojanowski JQ, Arnold SE. Cerebrovascular atherosclerosis correlates with Alzheimer pathology in neurodegenerative dementias. Brain : a Journal of Neurology. 135: 3749-56. PMID 23204143 DOI: 10.1093/Brain/Aws271 |
0.749 |
|
2012 |
Patel S, Lee EB, Xie SX, Law A, Jackson EM, Arnold SE, Clark CM, Shaw LM, Grady MS, Trojanowski JQ, Hamilton RH. Phosphorylated tau/amyloid beta 1-42 ratio in ventricular cerebrospinal fluid reflects outcome in idiopathic normal pressure hydrocephalus. Fluids and Barriers of the Cns. 9: 7. PMID 22444461 DOI: 10.1186/2045-8118-9-7 |
0.598 |
|
2012 |
Brettschneider J, Van Deerlin VM, Robinson JL, Kwong L, Lee EB, Ali YO, Safren N, Monteiro MJ, Toledo JB, Elman L, McCluskey L, Irwin DJ, Grossman M, Molina-Porcel L, Lee VM, et al. Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion. Acta Neuropathologica. 123: 825-39. PMID 22426854 DOI: 10.1007/S00401-012-0970-Z |
0.704 |
|
2012 |
Lee EB, Lee VM, Trojanowski JQ. Gains or losses: molecular mechanisms of TDP43-mediated neurodegeneration. Nature Reviews. Neuroscience. 13: 38-50. PMID 22127299 DOI: 10.1038/Nrn3121 |
0.674 |
|
2012 |
Yarchoan M, Xie SX, Kling MA, Toledo JB, Wolk DA, Lee EB, Van Deerlin VM, Virginia ML, Trojanowski JQ, Arnold SE. S5-02-04: Relationships of cerebrovascular atherosclerosis with amyloid, tau, α-synuclein and TDP-43 pathologies in neurodegenerative disease dementias Alzheimer's & Dementia. 8: P725-P725. DOI: 10.1016/J.Jalz.2012.05.1951 |
0.642 |
|
2011 |
Lee EB. Obesity, leptin, and Alzheimer's disease. Annals of the New York Academy of Sciences. 1243: 15-29. PMID 22211890 DOI: 10.1111/J.1749-6632.2011.06274.X |
0.36 |
|
2011 |
Lim Y, Kehm VM, Lee EB, Soper JH, Li C, Trojanowski JQ, Lee VM. α-Syn suppression reverses synaptic and memory defects in a mouse model of dementia with Lewy bodies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 10076-87. PMID 21734300 DOI: 10.1523/Jneurosci.0618-11.2011 |
0.796 |
|
2011 |
Winton MJ, Lee EB, Sun E, Wong MM, Leight S, Zhang B, Trojanowski JQ, Lee VM. Intraneuronal APP, not free Aβ peptides in 3xTg-AD mice: implications for tau versus Aβ-mediated Alzheimer neurodegeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7691-9. PMID 21613482 DOI: 10.1523/Jneurosci.6637-10.2011 |
0.711 |
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2011 |
Igaz LM, Kwong LK, Lee EB, Chen-Plotkin A, Swanson E, Unger T, Malunda J, Xu Y, Winton MJ, Trojanowski JQ, Lee VM. Dysregulation of the ALS-associated gene TDP-43 leads to neuronal death and degeneration in mice. The Journal of Clinical Investigation. 121: 726-38. PMID 21206091 DOI: 10.1172/Jci44867 |
0.79 |
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2010 |
Hamilton R, Patel S, Lee EB, Jackson EM, Lopinto J, Arnold SE, Clark CM, Basil A, Shaw LM, Xie SX, Grady MS, Trojanowski JQ. Lack of shunt response in suspected idiopathic normal pressure hydrocephalus with Alzheimer disease pathology. Annals of Neurology. 68: 535-40. PMID 20687117 DOI: 10.1002/Ana.22015 |
0.609 |
|
2010 |
Prasad S, Lee EB, Woo JH, Alavi A, Galetta SL. Photo essay. MRI and positron emission tomography findings in Heidenhain variant Creutzfeldt-Jakob disease. Journal of Neuro-Ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society. 30: 260-2. PMID 20581692 DOI: 10.1097/Wno.0B013E3181E2Aef7 |
0.331 |
|
2010 |
Arnold SE, Lee EB, Moberg PJ, Stutzbach L, Kazi H, Han LY, Lee VM, Trojanowski JQ. Olfactory epithelium amyloid-beta and paired helical filament-tau pathology in Alzheimer disease. Annals of Neurology. 67: 462-9. PMID 20437581 DOI: 10.1002/Ana.21910 |
0.742 |
|
2009 |
Turkeltaub PE, Guzman MA, Lee EB, Galetta SL. Idiopathic eosinophilic meningoencephalomyelitis following Well syndrome. Neurology. 73: 2037-9. PMID 19996079 DOI: 10.1212/Wnl.0B013E3181C55Ee7 |
0.517 |
|
2009 |
Lee EB, Tihan T, Scheithauer BW, Zhang PJ, Gonatas NK. Thyroid transcription factor 1 expression in sellar tumors: a histogenetic marker? Journal of Neuropathology and Experimental Neurology. 68: 482-8. PMID 19525896 DOI: 10.1097/Nen.0B013E3181A13Fca |
0.628 |
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2009 |
Ko MW, Turkeltaub PE, Lee EB, Gonatas NK, Volpe NJ, Moster ML, Galetta SL. Primary diffuse leptomeningeal gliomatosis mimicking a chronic inflammatory meningitis. Journal of the Neurological Sciences. 278: 127-31. PMID 19135216 DOI: 10.1016/J.Jns.2008.11.026 |
0.644 |
|
2009 |
Neumann M, Kwong LK, Lee EB, Kremmer E, Flatley A, Xu Y, Forman MS, Troost D, Kretzschmar HA, Trojanowski JQ, Lee VM. Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies. Acta Neuropathologica. 117: 137-49. PMID 19125255 DOI: 10.1007/S00401-008-0477-9 |
0.81 |
|
2008 |
Lee EB, Lee VM, Trojanowski JQ, Neumann M. TDP-43 immunoreactivity in anoxic, ischemic and neoplastic lesions of the central nervous system. Acta Neuropathologica. 115: 305-11. PMID 18087705 DOI: 10.1007/S00401-007-0331-5 |
0.711 |
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2007 |
Prasad S, Ko MW, Lee EB, Gonatas NK, Stern MB, Galetta S. Supranuclear vertical gaze abnormalities in sporadic Creutzfeldt-Jakob disease. Journal of the Neurological Sciences. 253: 69-72. PMID 17234215 DOI: 10.1016/J.Jns.2006.11.010 |
0.672 |
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2006 |
Lee EB, Leng LZ, Zhang B, Kwong L, Trojanowski JQ, Abel T, Lee VM. Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice. The Journal of Biological Chemistry. 281: 4292-9. PMID 16361260 DOI: 10.1074/Jbc.M511018200 |
0.691 |
|
2005 |
Lee EB, Leng LZ, Lee VM, Trojanowski JQ. Meningoencephalitis associated with passive immunization of a transgenic murine model of Alzheimer's amyloidosis. Febs Letters. 579: 2564-8. PMID 15862291 DOI: 10.1016/J.Febslet.2005.03.070 |
0.688 |
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2005 |
Lazarov O, Morfini GA, Lee EB, Farah MH, Szodorai A, DeBoer SR, Koliatsos VE, Kins S, Lee VM, Wong PC, Price DL, Brady ST, Sisodia SS. Axonal transport, amyloid precursor protein, kinesin-1, and the processing apparatus: revisited. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2386-95. PMID 15745965 DOI: 10.1523/Jneurosci.3089-04.2005 |
0.581 |
|
2005 |
Lee EB, Zhang B, Liu K, Greenbaum EA, Doms RW, Trojanowski JQ, Lee VM. BACE overexpression alters the subcellular processing of APP and inhibits Abeta deposition in vivo. The Journal of Cell Biology. 168: 291-302. PMID 15642747 DOI: 10.1083/Jcb.200407070 |
0.743 |
|
2005 |
Zhang B, Maiti A, Shively S, Lakhani F, McDonald-Jones G, Bruce J, Lee EB, Xie SX, Joyce S, Li C, Toleikis PM, Lee VM, Trojanowski JQ. Microtubule-binding drugs offset tau sequestration by stabilizing microtubules and reversing fast axonal transport deficits in a tauopathy model. Proceedings of the National Academy of Sciences of the United States of America. 102: 227-31. PMID 15615853 DOI: 10.1073/Pnas.0406361102 |
0.669 |
|
2004 |
Sung S, Yang H, Uryu K, Lee EB, Zhao L, Shineman D, Trojanowski JQ, Lee VM, Praticò D. Modulation of nuclear factor-kappa B activity by indomethacin influences A beta levels but not A beta precursor protein metabolism in a model of Alzheimer's disease. The American Journal of Pathology. 165: 2197-206. PMID 15579461 DOI: 10.1016/S0002-9440(10)63269-5 |
0.792 |
|
2004 |
Yang H, Yao Y, Uryu K, Lee EB, Zhao L, Funk C, Trojanowski JQ, Lee VM, Pratico D. P2-112 Selective suppression of NF-κB by indomethacin modulates Aβlevels and deposition but not metabolism in a model of Alzheimer disease Neurobiology of Aging. 25: S256. DOI: 10.1016/S0197-4580(04)80859-5 |
0.679 |
|
2003 |
Watson DJ, Longhi L, Lee EB, Fulp CT, Fujimoto S, Royo NC, Passini MA, Trojanowski JQ, Lee VM, McIntosh TK, Wolfe JH. Genetically modified NT2N human neuronal cells mediate long-term gene expression as CNS grafts in vivo and improve functional cognitive outcome following experimental traumatic brain injury. Journal of Neuropathology and Experimental Neurology. 62: 368-80. PMID 12722829 DOI: 10.1093/Jnen/62.4.368 |
0.652 |
|
2003 |
Lee EB, Skovronsky DM, Abtahian F, Doms RW, Lee VM. Secretion and intracellular generation of truncated Abeta in beta-site amyloid-beta precursor protein-cleaving enzyme expressing human neurons. The Journal of Biological Chemistry. 278: 4458-66. PMID 12480937 DOI: 10.1074/Jbc.M210105200 |
0.803 |
|
2001 |
Raben N, Danon M, Lu N, Lee E, Shliselfeld L, Skurat AV, Roach PJ, Lawrence JC, Musumeci O, Shanske S, DiMauro S, Plotz P. Surprises of genetic engineering: a possible model of polyglucosan body disease. Neurology. 56: 1739-45. PMID 11425943 DOI: 10.1212/Wnl.56.12.1739 |
0.341 |
|
1998 |
Lindstrom J, Peng X, Kuryatov A, Lee E, Anand R, Gerzanich V, Wang F, Wells G, Nelson M. Molecular and antigenic structure of nicotinic acetylcholine receptors Annals of the New York Academy of Sciences. 841: 71-86. PMID 9668222 DOI: 10.1111/J.1749-6632.1998.Tb10910.X |
0.58 |
|
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