| Year |
Citation |
Score |
| 2022 |
Cao M, Isaac R, Yan W, Ruan X, Jiang L, Wan Y, Wang J, Wang E, Caron C, Neben S, Drygin D, Pizzo DP, Wu X, Liu X, Chin AR, ... ... Olefsky JM, et al. Cancer-cell-secreted extracellular vesicles suppress insulin secretion through miR-122 to impair systemic glucose homeostasis and contribute to tumour growth. Nature Cell Biology. PMID 35637408 DOI: 10.1038/s41556-022-00919-7 |
0.457 |
|
| 2022 |
Rohm TV, Meier DT, Olefsky JM, Donath MY. Inflammation in obesity, diabetes, and related disorders. Immunity. 55: 31-55. PMID 35021057 DOI: 10.1016/j.immuni.2021.12.013 |
0.307 |
|
| 2021 |
Ji Y, Luo Z, Gao H, Dos Reis FCG, Bandyopadhyay G, Jin Z, Manda KA, Isaac R, Yang M, Fu W, Ying W, Olefsky JM. Hepatocyte-derived exosomes from early onset obese mice promote insulin sensitivity through miR-3075. Nature Metabolism. PMID 34489604 DOI: 10.1038/s42255-021-00444-1 |
0.42 |
|
| 2021 |
Ying W, Gao H, Dos Reis FCG, Bandyopadhyay G, Ofrecio JM, Luo Z, Ji Y, Jin Z, Ly C, Olefsky JM. MiR-690, an exosomal-derived miRNA from M2-polarized macrophages, improves insulin sensitivity in obese mice. Cell Metabolism. PMID 33450179 DOI: 10.1016/j.cmet.2020.12.019 |
0.376 |
|
| 2020 |
Paschoal VA, Walenta E, Talukdar S, Pessentheiner AR, Osborn O, Hah N, Chi TJ, Tye GL, Armando AM, Evans RM, Chi NW, Quehenberger O, Olefsky JM, Oh DY. Positive Reinforcing Mechanisms between GPR120 and PPARγ Modulate Insulin Sensitivity. Cell Metabolism. PMID 32413335 DOI: 10.1016/J.Cmet.2020.04.020 |
0.635 |
|
| 2019 |
Ying W, Fu W, Lee YS, Olefsky JM. The role of macrophages in obesity-associated islet inflammation and β-cell abnormalities. Nature Reviews. Endocrinology. PMID 31836875 DOI: 10.1038/S41574-019-0286-3 |
0.424 |
|
| 2019 |
El Ouarrat D, Isaac R, Lee YS, Oh DY, Wollam J, Lackey D, Riopel M, Bandyopadhyay G, Seo JB, Sampath-Kumar R, Olefsky JM. TAZ Is a Negative Regulator of PPARγ Activity in Adipocytes and TAZ Deletion Improves Insulin Sensitivity and Glucose Tolerance. Cell Metabolism. PMID 31708444 DOI: 10.1016/J.Cmet.2019.10.003 |
0.612 |
|
| 2019 |
Seo JB, Riopel M, Cabrales P, Huh JY, Bandyopadhyay GK, Andreyev AY, Murphy AN, Beeman SC, Smith GI, Klein S, Lee YS, Olefsky JM. Knockdown of Reduces Adipocyte Hypoxia And Improves Insulin Resistance in Obesity. Nature Metabolism. 1: 86-97. PMID 31528845 DOI: 10.1038/s42255-018-0003-x |
0.359 |
|
| 2019 |
Wollam J, Riopel M, Xu YJ, Johnson AMF, Ofrecio JM, Ying W, El Ouarrat D, Chan LS, Han AW, Mahmood NA, Ryan CN, Lee YS, Watrous JD, Chordia MD, Pan D, ... ... Olefsky JM, et al. The Microbiota-Produced -Formyl Peptide fMLF Promotes Obesity-Induced Glucose Intolerance. Diabetes. PMID 31010956 DOI: 10.2337/Db18-1307 |
0.438 |
|
| 2019 |
Rickert E, Fernandez MO, Choi I, Gorman M, Olefsky JM, Webster NJG. Neuronal SIRT1 Regulates Metabolic and Reproductive Function and the Response to Caloric Restriction. Journal of the Endocrine Society. 3: 427-445. PMID 30746504 DOI: 10.1210/Js.2018-00318 |
0.336 |
|
| 2018 |
Ying W, Lee YS, Dong Y, Seidman JS, Yang M, Isaac R, Seo JB, Yang BH, Wollam J, Riopel M, McNelis J, Glass CK, Olefsky JM, Fu W. Expansion of Islet-Resident Macrophages Leads to Inflammation Affecting β Cell Proliferation and Function in Obesity. Cell Metabolism. PMID 30595478 DOI: 10.1016/J.Cmet.2018.12.003 |
0.379 |
|
| 2018 |
Hoveyda HR, Fraser GL, Zoute L, Dutheuil G, Schils D, Brantis C, Lapin A, Parcq J, Guitard S, Lenoir F, Bousmaqui ME, Rorive S, Hospied S, Blanc S, Bernard J, ... ... Olefsky JM, et al. N-Thiazolylamide-based free fatty-acid 2 receptor agonists: Discovery, lead optimization and demonstration of off-target effect in a diabetes model. Bioorganic & Medicinal Chemistry. PMID 30253886 DOI: 10.1016/J.Bmc.2018.09.015 |
0.333 |
|
| 2018 |
Skorobogatko Y, Dragan M, Cordon C, Reilly SM, Hung CW, Xia W, Zhao P, Wallace M, Lackey DE, Chen XW, Osborn O, Bogner-Strauss JG, Theodorescu D, Metallo CM, Olefsky JM, et al. RalA controls glucose homeostasis by regulating glucose uptake in brown fat. Proceedings of the National Academy of Sciences of the United States of America. PMID 29915037 DOI: 10.1073/Pnas.1801050115 |
0.556 |
|
| 2018 |
Riopel M, Seo JB, Bandyopadhyay GK, Li P, Wollam J, Chung H, Jung SR, Murphy A, Wilson M, de Jong R, Patel S, Balakrishna D, Bilakovics J, Fanjul A, Plonowski A, ... ... Olefsky JM, et al. Chronic fractalkine administration improves glucose tolerance and pancreatic endocrine function. The Journal of Clinical Investigation. PMID 29504946 DOI: 10.1172/Jci94330 |
0.61 |
|
| 2018 |
Lee YS, Wollam J, Olefsky JM. An Integrated View of Immunometabolism. Cell. 172: 22-40. PMID 29328913 DOI: 10.1016/J.Cell.2017.12.025 |
0.502 |
|
| 2017 |
Ying W, Riopel M, Bandyopadhyay G, Dong Y, Birmingham A, Seo JB, Ofrecio JM, Wollam J, Hernandez-Carretero A, Fu W, Li P, Olefsky JM. Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity. Cell. PMID 28942920 DOI: 10.1016/J.Cell.2017.08.035 |
0.509 |
|
| 2017 |
Ying W, Wollam J, Ofrecio JM, Bandyopadhyay G, El Ouarrat D, Lee YS, Oh DY, Li P, Osborn O, Olefsky JM. Adipose tissue B2 cells promote insulin resistance through leukotriene LTB4/LTB4R1 signaling. The Journal of Clinical Investigation. PMID 28192375 DOI: 10.1172/Jci90350 |
0.558 |
|
| 2017 |
Saltiel AR, Olefsky JM. Inflammatory mechanisms linking obesity and metabolic disease. The Journal of Clinical Investigation. 127: 1-4. PMID 28045402 DOI: 10.1172/Jci92035 |
0.333 |
|
| 2016 |
Fernandez MO, Sharma S, Kim S, Rickert E, Hsueh K, Hwang V, Olefsky JM, Webster NJ. Obese neuronal PPARγ knock-out mice are leptin sensitive but show impaired glucose tolerance and fertility. Endocrinology. en20161818. PMID 27841948 DOI: 10.1210/En.2016-1818 |
0.405 |
|
| 2016 |
Li P, Liu S, Lu M, Bandyopadhyay G, Oh D, Imamura T, Johnson AM, Sears D, Shen Z, Cui B, Kong L, Hou S, Liang X, Iovino S, Watkins SM, ... ... Olefsky JM, et al. Hematopoietic-Derived Galectin-3 Causes Cellular and Systemic Insulin Resistance. Cell. 167: 973-984.e12. PMID 27814523 DOI: 10.1016/J.Cell.2016.10.025 |
0.661 |
|
| 2016 |
Oh DY, Olefsky JM. G protein-coupled receptors as targets for anti-diabetic therapeutics. Nature Reviews. Drug Discovery. PMID 26822831 DOI: 10.1038/Nrd.2015.4 |
0.478 |
|
| 2016 |
Lackey DE, Olefsky JM. Regulation of metabolism by the innate immune system. Nature Reviews. Endocrinology. 12: 15-28. PMID 26553134 DOI: 10.1038/Nrendo.2015.189 |
0.518 |
|
| 2015 |
Baeza-Raja B, Sachs BD, Li P, Christian F, Vagena E, Davalos D, Le Moan N, Ryu JK, Sikorski SL, Chan JP, Scadeng M, Taylor SS, Houslay MD, Baillie GS, Saltiel AR, ... Olefsky JM, et al. p75 Neurotrophin Receptor Regulates Energy Balance in Obesity. Cell Reports. PMID 26748707 DOI: 10.1016/J.Celrep.2015.12.028 |
0.414 |
|
| 2015 |
McNelis JC, Lee YS, Mayoral R, van der Kant R, Johnson AM, Wollam J, Olefsky JM. GPR43 potentiates beta cell function in obesity. Diabetes. PMID 26023106 DOI: 10.2337/Db14-1938 |
0.472 |
|
| 2015 |
Mayoral R, Osborn O, McNelis J, Johnson AM, Oh da Y, Izquierdo CL, Chung H, Li P, Traves PG, Bandyopadhyay G, Pessentheiner AR, Ofrecio JM, Cook JR, Qiang L, Accili D, ... Olefsky JM, et al. Adipocyte SIRT1 knockout promotes PPARγ activity, adipogenesis and insulin sensitivity in chronic-HFD and obesity. Molecular Metabolism. 4: 378-91. PMID 25973386 DOI: 10.1016/J.Molmet.2015.02.007 |
0.448 |
|
| 2015 |
Suh JM, Jonker JW, Ahmadian M, Goetz R, Lackey D, Osborn O, Huang Z, Liu W, Yoshihara E, van Dijk TH, Havinga R, Fan W, Yin YQ, Yu RT, Liddle C, ... ... Olefsky JM, et al. Corrigendum: Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. Nature. 520: 388. PMID 25739500 DOI: 10.1038/Nature14304 |
0.405 |
|
| 2015 |
Li P, Oh da Y, Bandyopadhyay G, Lagakos WS, Talukdar S, Osborn O, Johnson A, Chung H, Mayoral R, Maris M, Ofrecio JM, Taguchi S, Lu M, Olefsky JM. LTB4 promotes insulin resistance in obese mice by acting on macrophages, hepatocytes and myocytes. Nature Medicine. 21: 239-47. PMID 25706874 DOI: 10.1038/Nm.3800 |
0.634 |
|
| 2015 |
Fang S, Suh JM, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, ... ... Olefsky JM, et al. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nature Medicine. 21: 159-65. PMID 25559344 DOI: 10.1038/Nm.3760 |
0.401 |
|
| 2015 |
Morinaga H, Mayoral R, Heinrichsdorff J, Osborn O, Franck N, Hah N, Walenta E, Bandyopadhyay G, Pessentheiner AR, Chi TJ, Chung H, Bogner-Strauss JG, Evans RM, Olefsky JM, Oh da Y. Characterization of distinct subpopulations of hepatic macrophages in HFD/obese mice. Diabetes. 64: 1120-30. PMID 25315009 DOI: 10.2337/Db14-1238 |
0.336 |
|
| 2015 |
Chung H, Lee YS, Mayoral R, Oh DY, Siu JT, Webster NJ, Sears DD, Olefsky JM, Ellies LG. Omega-3 fatty acids reduce obesity-induced tumor progression independent of GPR120 in a mouse model of postmenopausal breast cancer. Oncogene. 34: 3504-13. PMID 25220417 DOI: 10.1038/Onc.2014.283 |
0.307 |
|
| 2014 |
Suh JM, Jonker JW, Ahmadian M, Goetz R, Lackey D, Osborn O, Huang Z, Liu W, Yoshihara E, van Dijk TH, Havinga R, Fan W, Yin YQ, Yu RT, Liddle C, ... ... Olefsky JM, et al. Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer. Nature. 513: 436-9. PMID 25043058 DOI: 10.1038/Nature13540 |
0.652 |
|
| 2014 |
McNelis JC, Olefsky JM. Macrophages, immunity, and metabolic disease. Immunity. 41: 36-48. PMID 25035952 DOI: 10.1016/J.Immuni.2014.05.010 |
0.465 |
|
| 2014 |
Oh da Y, Walenta E, Akiyama TE, Lagakos WS, Lackey D, Pessentheiner AR, Sasik R, Hah N, Chi TJ, Cox JM, Powels MA, Di Salvo J, Sinz C, Watkins SM, Armando AM, ... ... Olefsky JM, et al. A Gpr120-selective agonist improves insulin resistance and chronic inflammation in obese mice. Nature Medicine. 20: 942-7. PMID 24997608 DOI: 10.1038/Nm.3614 |
0.56 |
|
| 2014 |
Inokuchi-Shimizu S, Park EJ, Roh YS, Yang L, Zhang B, Song J, Liang S, Pimienta M, Taniguchi K, Wu X, Asahina K, Lagakos W, Mackey MR, Akira S, Ellisman MH, ... ... Olefsky JM, et al. TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis. The Journal of Clinical Investigation. 124: 3566-78. PMID 24983318 DOI: 10.1172/Jci74068 |
0.308 |
|
| 2014 |
Lee YS, Kim JW, Osborne O, Oh da Y, Sasik R, Schenk S, Chen A, Chung H, Murphy A, Watkins SM, Quehenberger O, Johnson RS, Olefsky JM. Increased adipocyte O2 consumption triggers HIF-1α, causing inflammation and insulin resistance in obesity. Cell. 157: 1339-52. PMID 24906151 DOI: 10.1016/J.Cell.2014.05.012 |
0.515 |
|
| 2014 |
Lee B, Qiao L, Lu M, Yoo HS, Cheung W, Mak R, Schaack J, Feng GS, Chi NW, Olefsky JM, Shao J. C/EBPα regulates macrophage activation and systemic metabolism. American Journal of Physiology. Endocrinology and Metabolism. 306: E1144-54. PMID 24691027 DOI: 10.1152/Ajpendo.00002.2014 |
0.409 |
|
| 2014 |
Fink LN, Costford SR, Lee YS, Jensen TE, Bilan PJ, Oberbach A, Blüher M, Olefsky JM, Sams A, Klip A. Pro-inflammatory macrophages increase in skeletal muscle of high fat-fed mice and correlate with metabolic risk markers in humans. Obesity (Silver Spring, Md.). 22: 747-57. PMID 24030890 DOI: 10.1002/Oby.20615 |
0.394 |
|
| 2013 |
Li P, Spann NJ, Kaikkonen MU, Lu M, Oh da Y, Fox JN, Bandyopadhyay G, Talukdar S, Xu J, Lagakos WS, Patsouris D, Armando A, Quehenberger O, Dennis EA, Watkins SM, ... ... Olefsky JM, et al. NCoR repression of LXRs restricts macrophage biosynthesis of insulin-sensitizing omega 3 fatty acids. Cell. 155: 200-14. PMID 24074869 DOI: 10.1016/J.Cell.2013.08.054 |
0.484 |
|
| 2013 |
Ravnskjaer K, Hogan MF, Lackey D, Tora L, Dent SY, Olefsky J, Montminy M. Glucagon regulates gluconeogenesis through KAT2B- and WDR5-mediated epigenetic effects. The Journal of Clinical Investigation. 123: 4318-28. PMID 24051374 DOI: 10.1172/Jci69035 |
0.472 |
|
| 2013 |
Guo Y, Darshi M, Ma Y, Perkins GA, Shen Z, Haushalter KJ, Saito R, Chen A, Lee YS, Patel HH, Briggs SP, Ellisman MH, Olefsky JM, Taylor SS. Quantitative proteomic and functional analysis of liver mitochondria from high fat diet (HFD) diabetic mice. Molecular & Cellular Proteomics : McP. 12: 3744-58. PMID 24030101 DOI: 10.1074/Mcp.M113.027441 |
0.38 |
|
| 2013 |
Lee YS, Morinaga H, Kim JJ, Lagakos W, Taylor S, Keshwani M, Perkins G, Dong H, Kayali AG, Sweet IR, Olefsky J. The Fractalkine/CX3CR1 System Regulates β Cell Function and Insulin Secretion Cell. 153: 413-425. PMID 23582329 DOI: 10.1016/J.Cell.2013.03.001 |
0.583 |
|
| 2013 |
Sharma S, Morinaga H, Hwang V, Fan W, Fernandez MO, Varki N, Olefsky JM, Webster NJ. Free fatty acids induce Lhb mRNA but suppress Fshb mRNA in pituitary LβT2 gonadotropes and diet-induced obesity reduces FSH levels in male mice and disrupts the proestrous LH/FSH surge in female mice. Endocrinology. 154: 2188-99. PMID 23525221 DOI: 10.1210/En.2012-2218 |
0.367 |
|
| 2013 |
Lu M, Sarruf DA, Li P, Osborn O, Sanchez-Alavez M, Talukdar S, Chen A, Bandyopadhyay G, Xu J, Morinaga H, Dines K, Watkins S, Kaiyala K, Schwartz MW, Olefsky JM. Neuronal Sirt1 deficiency increases insulin sensitivity in both brain and peripheral tissues. The Journal of Biological Chemistry. 288: 10722-35. PMID 23457303 DOI: 10.1074/Jbc.M112.443606 |
0.628 |
|
| 2013 |
Johnson AM, Olefsky JM. The origins and drivers of insulin resistance. Cell. 152: 673-84. PMID 23415219 DOI: 10.1016/J.Cell.2013.01.041 |
0.557 |
|
| 2013 |
Reilly SM, Chiang SH, Decker SJ, Chang L, Uhm M, Larsen MJ, Rubin JR, Mowers J, White NM, Hochberg I, Downes M, Yu RT, Liddle C, Evans RM, Oh D, ... ... Olefsky JM, et al. An inhibitor of the protein kinases TBK1 and IKK-É› improves obesity-related metabolic dysfunctions in mice. Nature Medicine. 19: 313-21. PMID 23396211 DOI: 10.1038/Nm.3082 |
0.43 |
|
| 2013 |
Jiao J, Bae EJ, Bandyopadhyay G, Oliver J, Marathe C, Chen M, Hsu JY, Chen Y, Tian H, Olefsky JM, Saberi M. Restoration of euglycemia after duodenal bypass surgery is reliant on central and peripheral inputs in Zucker fa/fa rats Diabetes. 62: 1074-1083. PMID 23248171 DOI: 10.2337/Db12-0681 |
0.58 |
|
| 2013 |
Qatanani M, Tan Y, Dobrin R, Greenawalt DM, Hu G, Zhao W, Olefsky JM, Sears DD, Kaplan LM, Kemp DM. Inverse regulation of inflammation and mitochondrial function in adipose tissue defines extreme insulin sensitivity in morbidly obese patients. Diabetes. 62: 855-63. PMID 23223024 DOI: 10.2337/Db12-0399 |
0.566 |
|
| 2013 |
Xu J, Morinaga H, Oh D, Li P, Chen A, Talukdar S, Lazarowski E, Olefsky JM, Kim JJ. Correction: GPR105 Ablation Prevents Inflammation and Improves Insulin Sensitivity in Mice with Diet-Induced Obesity The Journal of Immunology. 190: 1380-1380. DOI: 10.4049/Jimmunol.1290082 |
0.484 |
|
| 2012 |
Lee JH, Budanov AV, Talukdar S, Park EJ, Park HL, Park HW, Bandyopadhyay G, Li N, Aghajan M, Jang I, Wolfe AM, Perkins GA, Ellisman MH, Bier E, Scadeng M, ... ... Olefsky J, et al. Maintenance of metabolic homeostasis by Sestrin2 and Sestrin3. Cell Metabolism. 16: 311-21. PMID 22958918 DOI: 10.1016/J.Cmet.2012.08.004 |
0.513 |
|
| 2012 |
Heinrichsdorff J, Olefsky JM. Fetuin-A: the missing link in lipid-induced inflammation. Nature Medicine. 18: 1182-3. PMID 22869185 DOI: 10.1038/Nm.2869 |
0.448 |
|
| 2012 |
Talukdar S, Oh da Y, Bandyopadhyay G, Li D, Xu J, McNelis J, Lu M, Li P, Yan Q, Zhu Y, Ofrecio J, Lin M, Brenner MB, Olefsky JM. Neutrophils mediate insulin resistance in mice fed a high-fat diet through secreted elastase. Nature Medicine. 18: 1407-12. PMID 22863787 DOI: 10.1038/Nm.2885 |
0.536 |
|
| 2012 |
Xu J, Morinaga H, Oh D, Li P, Chen A, Talukdar S, Mamane Y, Mancini JA, Nawrocki AR, Lazarowski E, Olefsky JM, Kim JJ. GPR105 ablation prevents inflammation and improves insulin sensitivity in mice with diet-induced obesity. Journal of Immunology (Baltimore, Md. : 1950). 189: 1992-9. PMID 22778393 DOI: 10.4049/Jimmunol.1103207 |
0.542 |
|
| 2012 |
Osborn O, Oh DY, McNelis J, Sanchez-Alavez M, Talukdar S, Lu M, Li P, Thiede L, Morinaga H, Kim JJ, Heinrichsdorff J, Nalbandian S, Ofrecio JM, Scadeng M, Schenk S, ... ... Olefsky JM, et al. G protein-coupled receptor 21 deletion improves insulin sensitivity in diet-induced obese mice. The Journal of Clinical Investigation. 122: 2444-53. PMID 22653059 DOI: 10.1172/Jci61953 |
0.588 |
|
| 2012 |
Glass CK, Olefsky JM. Inflammation and lipid signaling in the etiology of insulin resistance. Cell Metabolism. 15: 635-45. PMID 22560216 DOI: 10.1016/J.Cmet.2012.04.001 |
0.362 |
|
| 2012 |
Oh DY, Olefsky JM. Omega 3 fatty acids and GPR120. Cell Metabolism. 15: 564-5. PMID 22560206 DOI: 10.1016/J.Cmet.2012.04.009 |
0.412 |
|
| 2012 |
Jonker JW, Suh JM, Atkins AR, Ahmadian M, Li P, Whyte J, He M, Juguilon H, Yin YQ, Phillips CT, Yu RT, Olefsky JM, Henry RR, Downes M, Evans RM. A PPARγ-FGF1 axis is required for adaptive adipose remodelling and metabolic homeostasis. Nature. 485: 391-4. PMID 22522926 DOI: 10.1038/Nature10998 |
0.4 |
|
| 2012 |
Kim JJ, Fan W, Olefsky JM. Putting the brakes on FOXO1 in fat. The Embo Journal. 31: 2240-1. PMID 22510885 DOI: 10.1038/Emboj.2012.116 |
0.535 |
|
| 2012 |
Bae EJ, Xu J, Oh DY, Bandyopadhyay G, Lagakos WS, Keshwani M, Olefsky JM. Liver-specific p70 S6 kinase depletion protects against hepatic steatosis and systemic insulin resistance. The Journal of Biological Chemistry. 287: 18769-80. PMID 22493495 DOI: 10.1074/Jbc.M112.365544 |
0.597 |
|
| 2012 |
Baeza-Raja B, Li P, Le Moan N, Sachs BD, Schachtrup C, Davalos D, Vagena E, Bridges D, Kim C, Saltiel AR, Olefsky JM, Akassoglou K. p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 109: 5838-43. PMID 22460790 DOI: 10.1073/Pnas.1103638109 |
0.625 |
|
| 2012 |
Oh DY, Morinaga H, Talukdar S, Bae EJ, Olefsky JM. Increased macrophage migration into adipose tissue in obese mice. Diabetes. 61: 346-54. PMID 22190646 DOI: 10.2337/Db11-0860 |
0.331 |
|
| 2011 |
Li P, Fan W, Xu J, Lu M, Yamamoto H, Auwerx J, Sears DD, Talukdar S, Oh D, Chen A, Bandyopadhyay G, Scadeng M, Ofrecio JM, Nalbandian S, Olefsky JM. Adipocyte NCoR knockout decreases PPARγ phosphorylation and enhances PPARγ activity and insulin sensitivity. Cell. 147: 815-26. PMID 22078880 DOI: 10.1016/J.Cell.2011.09.050 |
0.61 |
|
| 2011 |
Schenk S, McCurdy CE, Philp A, Chen MZ, Holliday MJ, Bandyopadhyay GK, Osborn O, Baar K, Olefsky JM. Sirt1 enhances skeletal muscle insulin sensitivity in mice during caloric restriction. The Journal of Clinical Investigation. 121: 4281-8. PMID 21985785 DOI: 10.1172/Jci58554 |
0.54 |
|
| 2011 |
Lee YS, Li P, Huh JY, Hwang IJ, Lu M, Kim JI, Ham M, Talukdar S, Chen A, Lu WJ, Bandyopadhyay GK, Schwendener R, Olefsky J, Kim JB. Inflammation is necessary for long-term but not short-term high-fat diet-induced insulin resistance. Diabetes. 60: 2474-83. PMID 21911747 DOI: 10.2337/Db11-0194 |
0.553 |
|
| 2011 |
Ohtsubo K, Chen MZ, Olefsky JM, Marth JD. Pathway to diabetes through attenuation of pancreatic beta cell glycosylation and glucose transport. Nature Medicine. 17: 1067-75. PMID 21841783 DOI: 10.1038/Nm.2414 |
0.48 |
|
| 2011 |
Talukdar S, Olefsky JM, Osborn O. Targeting GPR120 and other fatty acid-sensing GPCRs ameliorates insulin resistance and inflammatory diseases. Trends in Pharmacological Sciences. 32: 543-50. PMID 21663979 DOI: 10.1016/J.Tips.2011.04.004 |
0.428 |
|
| 2011 |
Lu M, Sarruf DA, Talukdar S, Sharma S, Li P, Bandyopadhyay G, Nalbandian S, Fan W, Gayen JR, Mahata SK, Webster NJ, Schwartz MW, Olefsky JM. Brain PPAR-γ promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones. Nature Medicine. 17: 618-22. PMID 21532596 DOI: 10.1038/Nm.2332 |
0.51 |
|
| 2011 |
Osawa Y, Seki E, Kodama Y, Suetsugu A, Miura K, Adachi M, Ito H, Shiratori Y, Banno Y, Olefsky JM, Nagaki M, Moriwaki H, Brenner DA, Seishima M. Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1133-44. PMID 21163859 DOI: 10.1096/Fj.10-168351 |
0.439 |
|
| 2011 |
Sharma S, Sharma PM, Mistry DS, Chang RJ, Olefsky JM, Mellon PL, Webster NJ. PPARG regulates gonadotropin-releasing hormone signaling in LbetaT2 cells in vitro and pituitary gonadotroph function in vivo in mice. Biology of Reproduction. 84: 466-75. PMID 21076077 DOI: 10.1095/Biolreprod.110.088005 |
0.364 |
|
| 2010 |
Fan W, Morinaga H, Kim JJ, Bae E, Spann NJ, Heinz S, Glass CK, Olefsky JM. FoxO1 regulates Tlr4 inflammatory pathway signalling in macrophages. The Embo Journal. 29: 4223-36. PMID 21045807 DOI: 10.1038/Emboj.2010.268 |
0.391 |
|
| 2010 |
Oh DY, Talukdar S, Bae EJ, Imamura T, Morinaga H, Fan W, Li P, Lu WJ, Watkins SM, Olefsky JM. GPR120 is an omega-3 fatty acid receptor mediating potent anti-inflammatory and insulin-sensitizing effects. Cell. 142: 687-98. PMID 20813258 DOI: 10.1016/J.Cell.2010.07.041 |
0.492 |
|
| 2010 |
Oh DY, Olefsky JM. Medicine. Wnt fans the flames in obesity. Science (New York, N.Y.). 329: 397-8. PMID 20651140 DOI: 10.1126/Science.1193404 |
0.536 |
|
| 2010 |
Lu M, Li P, Pferdekamper J, Fan W, Saberi M, Schenk S, Olefsky JM. Inducible nitric oxide synthase deficiency in myeloid cells does not prevent diet-induced insulin resistance. Molecular Endocrinology (Baltimore, Md.). 24: 1413-22. PMID 20444886 DOI: 10.1210/Jcem.95.5.9993 |
0.556 |
|
| 2010 |
Miura K, Kodama Y, Inokuchi S, Schnabl B, Aoyama T, Ohnishi H, Olefsky JM, Brenner DA, Seki E. Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice. Gastroenterology. 139: 323-34.e7. PMID 20347818 DOI: 10.1053/J.Gastro.2010.03.052 |
0.35 |
|
| 2010 |
Li P, Lu M, Nguyen MT, Bae EJ, Chapman J, Feng D, Hawkins M, Pessin JE, Sears DD, Nguyen AK, Amidi A, Watkins SM, Nguyen U, Olefsky JM. Functional heterogeneity of CD11c-positive adipose tissue macrophages in diet-induced obese mice. The Journal of Biological Chemistry. 285: 15333-45. PMID 20308074 DOI: 10.1074/Jbc.M110.100263 |
0.511 |
|
| 2010 |
Lu M, Patsouris D, Li P, Flores-Riveros J, Frincke JM, Watkins S, Schenk S, Olefsky JM. A new antidiabetic compound attenuates inflammation and insulin resistance in Zucker diabetic fatty rats. American Journal of Physiology. Endocrinology and Metabolism. 298: E1036-48. PMID 20159859 DOI: 10.1152/Ajpendo.00668.2009 |
0.543 |
|
| 2010 |
Olefsky JM, Glass CK. Macrophages, inflammation, and insulin resistance. Annual Review of Physiology. 72: 219-46. PMID 20148674 DOI: 10.1146/Annurev-Physiol-021909-135846 |
0.568 |
|
| 2010 |
Wang T, Villegas S, Huang Y, White SK, Ahlem C, Lu M, Olefsky JM, Reading C, Frincke JM, Alleva D, Flores-Riveros J. Amelioration of glucose intolerance by the synthetic androstene HE3286: link to inflammatory pathways. The Journal of Pharmacology and Experimental Therapeutics. 333: 70-80. PMID 20068030 DOI: 10.1124/Jpet.109.161182 |
0.541 |
|
| 2010 |
Yoshizaki T, Schenk S, Imamura T, Babendure JL, Sonoda N, Bae EJ, Oh DY, Lu M, Milne JC, Westphal C, Bandyopadhyay G, Olefsky JM. SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity. American Journal of Physiology. Endocrinology and Metabolism. 298: E419-28. PMID 19996381 DOI: 10.1152/Ajpendo.00417.2009 |
0.528 |
|
| 2009 |
Sugii S, Olson P, Sears DD, Saberi M, Atkins AR, Barish GD, Hong SH, Castro GL, Yin YQ, Nelson MC, Hsiao G, Greaves DR, Downes M, Yu RT, Olefsky JM, et al. PPARgamma activation in adipocytes is sufficient for systemic insulin sensitization. Proceedings of the National Academy of Sciences of the United States of America. 106: 22504-9. PMID 20018750 DOI: 10.1073/Pnas.0912487106 |
0.577 |
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| 2009 |
Saberi M, Woods NB, de Luca C, Schenk S, Lu JC, Bandyopadhyay G, Verma IM, Olefsky JM. Hematopoietic cell-specific deletion of toll-like receptor 4 ameliorates hepatic and adipose tissue insulin resistance in high-fat-fed mice. Cell Metabolism. 10: 419-29. PMID 19883619 DOI: 10.1016/J.Cmet.2009.09.006 |
0.505 |
|
| 2009 |
Patsouris D, Neels JG, Fan W, Li PP, Nguyen MT, Olefsky JM. Glucocorticoids and thiazolidinediones interfere with adipocyte-mediated macrophage chemotaxis and recruitment. The Journal of Biological Chemistry. 284: 31223-35. PMID 19740750 DOI: 10.1074/Jbc.M109.041665 |
0.452 |
|
| 2009 |
Olefsky JM. IKKepsilon: a bridge between obesity and inflammation. Cell. 138: 834-6. PMID 19737512 DOI: 10.1016/J.Cell.2009.08.018 |
0.377 |
|
| 2009 |
Saberi M, Bjelica D, Schenk S, Imamura T, Bandyopadhyay G, Li P, Jadhar V, Vargeese C, Wang W, Bowman K, Zhang Y, Polisky B, Olefsky JM. Novel liver-specific TORC2 siRNA corrects hyperglycemia in rodent models of type 2 diabetes. American Journal of Physiology. Endocrinology and Metabolism. 297: E1137-46. PMID 19706791 DOI: 10.1152/Ajpendo.00158.2009 |
0.42 |
|
| 2009 |
Kim JJ, Li P, Huntley J, Chang JP, Arden KC, Olefsky JM. FoxO1 haploinsufficiency protects against high-fat diet-induced insulin resistance with enhanced peroxisome proliferator-activated receptor gamma activation in adipose tissue. Diabetes. 58: 1275-82. PMID 19289458 DOI: 10.2337/Db08-1001 |
0.593 |
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| 2009 |
Fan W, Imamura T, Sonoda N, Sears DD, Patsouris D, Kim JJ, Olefsky JM. FOXO1 transrepresses peroxisome proliferator-activated receptor gamma transactivation, coordinating an insulin-induced feed-forward response in adipocytes. The Journal of Biological Chemistry. 284: 12188-97. PMID 19246449 DOI: 10.1074/Jbc.M808915200 |
0.587 |
|
| 2009 |
Yoshizaki T, Milne JC, Imamura T, Schenk S, Sonoda N, Babendure JL, Lu JC, Smith JJ, Jirousek MR, Olefsky JM. SIRT1 exerts anti-inflammatory effects and improves insulin sensitivity in adipocytes. Molecular and Cellular Biology. 29: 1363-74. PMID 19103747 DOI: 10.1128/Mcb.00705-08 |
0.627 |
|
| 2009 |
Kayali A, Haruta T, Saltiel A, Olefsky J, Webster NJG. O-36: A possible role for phospholipase Cγ in insulin action? Experimental and Clinical Endocrinology & Diabetes. 104: 46-47. DOI: 10.1055/S-0029-1211527 |
0.518 |
|
| 2009 |
Morris AJ, Martin SS, Haruta T, Nelson JG, Gustafson TA, Mueckler M, Rose DW, Olefsky JM. O-20: Disruption of the interaction between the insulin receptor and IRS-1 does not impair insulin stimulated GLUT4 translocation Experimental and Clinical Endocrinology & Diabetes. 104: 29-29. DOI: 10.1055/S-0029-1211511 |
0.755 |
|
| 2008 |
Nofsinger RR, Li P, Hong SH, Jonker JW, Barish GD, Ying H, Cheng SY, Leblanc M, Xu W, Pei L, Kang YJ, Nelson M, Downes M, Yu RT, Olefsky JM, et al. SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 105: 20021-6. PMID 19066220 DOI: 10.1073/Pnas.0811012105 |
0.412 |
|
| 2008 |
Liu Y, Dentin R, Chen D, Hedrick S, Ravnskjaer K, Schenk S, Milne J, Meyers DJ, Cole P, Yates J, Olefsky J, Guarente L, Montminy M. A fasting inducible switch modulates gluconeogenesis via activator/coactivator exchange. Nature. 456: 269-73. PMID 18849969 DOI: 10.1038/Nature07349 |
0.451 |
|
| 2008 |
Patsouris D, Li PP, Thapar D, Chapman J, Olefsky JM, Neels JG. Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals. Cell Metabolism. 8: 301-9. PMID 18840360 DOI: 10.1016/J.Cmet.2008.08.015 |
0.527 |
|
| 2008 |
Olefsky JM. Fat talks, liver and muscle listen. Cell. 134: 914-6. PMID 18805083 DOI: 10.1016/J.Cell.2008.09.001 |
0.432 |
|
| 2008 |
Schenk S, Saberi M, Olefsky JM. Insulin sensitivity: modulation by nutrients and inflammation. The Journal of Clinical Investigation. 118: 2992-3002. PMID 18769626 DOI: 10.1172/Jci34260 |
0.576 |
|
| 2008 |
Sonoda N, Imamura T, Yoshizaki T, Babendure JL, Lu JC, Olefsky JM. Beta-Arrestin-1 mediates glucagon-like peptide-1 signaling to insulin secretion in cultured pancreatic beta cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 6614-9. PMID 18445652 DOI: 10.1073/Pnas.0710402105 |
0.465 |
|
| 2008 |
Féral CC, Neels JG, Kummer C, Slepak M, Olefsky JM, Ginsberg MH. Blockade of alpha4 integrin signaling ameliorates the metabolic consequences of high-fat diet-induced obesity. Diabetes. 57: 1842-51. PMID 18426864 DOI: 10.2337/Db07-1751 |
0.457 |
|
| 2008 |
Yang X, Ongusaha PP, Miles PD, Havstad JC, Zhang F, So WV, Kudlow JE, Michell RH, Olefsky JM, Field SJ, Evans RM. Phosphoinositide signalling links O-GlcNAc transferase to insulin resistance. Nature. 451: 964-9. PMID 18288188 DOI: 10.1038/Nature06668 |
0.569 |
|
| 2008 |
de Luca C, Olefsky JM. Inflammation and insulin resistance. Febs Letters. 582: 97-105. PMID 18053812 DOI: 10.1016/J.Febslet.2007.11.057 |
0.585 |
|
| 2008 |
Lu M, Tang Q, Olefsky JM, Mellon PL, Webster NJ. Adiponectin activates adenosine monophosphate-activated protein kinase and decreases luteinizing hormone secretion in LbetaT2 gonadotropes. Molecular Endocrinology (Baltimore, Md.). 22: 760-71. PMID 18006641 DOI: 10.1210/Me.2007-0330 |
0.406 |
|
| 2007 |
Milne JC, Lambert PD, Schenk S, Carney DP, Smith JJ, Gagne DJ, Jin L, Boss O, Perni RB, Vu CB, Bemis JE, Xie R, Disch JS, Ng PY, Nunes JJ, ... ... Olefsky JM, et al. Small molecule activators of SIRT1 as therapeutics for the treatment of type 2 diabetes. Nature. 450: 712-6. PMID 18046409 DOI: 10.1038/Nature06261 |
0.561 |
|
| 2007 |
Solinas G, Vilcu C, Neels JG, Bandyopadhyay GK, Luo JL, Naugler W, Grivennikov S, Wynshaw-Boris A, Scadeng M, Olefsky JM, Karin M. JNK1 in hematopoietically derived cells contributes to diet-induced inflammation and insulin resistance without affecting obesity. Cell Metabolism. 6: 386-97. PMID 17983584 DOI: 10.1016/J.Cmet.2007.09.011 |
0.619 |
|
| 2007 |
Sears DD, Hsiao A, Ofrecio JM, Chapman J, He W, Olefsky JM. Selective modulation of promoter recruitment and transcriptional activity of PPARgamma. Biochemical and Biophysical Research Communications. 364: 515-21. PMID 17963725 DOI: 10.1016/J.Bbrc.2007.10.057 |
0.319 |
|
| 2007 |
Nguyen MT, Favelyukis S, Nguyen AK, Reichart D, Scott PA, Jenn A, Liu-Bryan R, Glass CK, Neels JG, Olefsky JM. A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. The Journal of Biological Chemistry. 282: 35279-92. PMID 17916553 DOI: 10.1074/Jbc.M706762200 |
0.439 |
|
| 2007 |
Kawamata Y, Imamura T, Babendure JL, Lu JC, Yoshizaki T, Olefsky JM. Tumor necrosis factor receptor-1 can function through a G alpha q/11-beta-arrestin-1 signaling complex. The Journal of Biological Chemistry. 282: 28549-56. PMID 17664271 DOI: 10.1074/Jbc.M705869200 |
0.337 |
|
| 2007 |
Hevener AL, Olefsky JM, Reichart D, Nguyen MT, Bandyopadyhay G, Leung HY, Watt MJ, Benner C, Febbraio MA, Nguyen AK, Folian B, Subramaniam S, Gonzalez FJ, Glass CK, Ricote M. Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones. The Journal of Clinical Investigation. 117: 1658-69. PMID 17525798 DOI: 10.1172/Jci31561 |
0.572 |
|
| 2007 |
Yoshizaki T, Imamura T, Babendure JL, Lu JC, Sonoda N, Olefsky JM. Myosin 5a is an insulin-stimulated Akt2 (protein kinase Bbeta) substrate modulating GLUT4 vesicle translocation. Molecular and Cellular Biology. 27: 5172-83. PMID 17515613 DOI: 10.1128/Mcb.02298-06 |
0.507 |
|
| 2007 |
Liao W, Nguyen MT, Yoshizaki T, Favelyukis S, Patsouris D, Imamura T, Verma IM, Olefsky JM. Suppression of PPAR-gamma attenuates insulin-stimulated glucose uptake by affecting both GLUT1 and GLUT4 in 3T3-L1 adipocytes. American Journal of Physiology. Endocrinology and Metabolism. 293: E219-27. PMID 17389706 DOI: 10.1152/Ajpendo.00695.2006 |
0.581 |
|
| 2007 |
Miles PD, Treuner K, Latronica M, Olefsky JM, Barlow C. Impaired insulin secretion in a mouse model of ataxia telangiectasia. American Journal of Physiology. Endocrinology and Metabolism. 293: E70-4. PMID 17356010 DOI: 10.1152/Ajpendo.00259.2006 |
0.361 |
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| 2007 |
Lesniewski LA, Hosch SE, Neels JG, de Luca C, Pashmforoush M, Lumeng CN, Chiang SH, Scadeng M, Saltiel AR, Olefsky JM. Bone marrow-specific Cap gene deletion protects against high-fat diet-induced insulin resistance. Nature Medicine. 13: 455-62. PMID 17351624 DOI: 10.1038/Nm1550 |
0.6 |
|
| 2007 |
Hupfeld CJ, Olefsky JM. Regulation of receptor tyrosine kinase signaling by GRKs and beta-arrestins. Annual Review of Physiology. 69: 561-77. PMID 17002595 DOI: 10.1146/Annurev.Physiol.69.022405.154626 |
0.306 |
|
| 2007 |
Courtney CH, Olefsky JM. Insulin resistance Mechanisms of Insulin Action: Medical Intelligence Unit. 185-209. DOI: 10.1007/978-0-387-72204-7_10 |
0.526 |
|
| 2006 |
Bandyopadhyay GK, Yu JG, Ofrecio J, Olefsky JM. Increased malonyl-CoA levels in muscle from obese and type 2 diabetic subjects lead to decreased fatty acid oxidation and increased lipogenesis; thiazolidinedione treatment reverses these defects. Diabetes. 55: 2277-85. PMID 16873691 DOI: 10.2337/Db06-0062 |
0.442 |
|
| 2006 |
Hosch SE, Olefsky JM, Kim JJ. APPLied mechanics: uncovering how adiponectin modulates insulin action. Cell Metabolism. 4: 5-6. PMID 16814726 DOI: 10.1016/J.Cmet.2006.06.003 |
0.585 |
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| 2006 |
Neels JG, Olefsky JM. Cell signaling. A new way to burn fat. Science (New York, N.Y.). 312: 1756-8. PMID 16794069 DOI: 10.1126/Science.1130476 |
0.458 |
|
| 2006 |
Liao W, Nguyen MT, Imamura T, Singer O, Verma IM, Olefsky JM. Lentiviral short hairpin ribonucleic acid-mediated knockdown of GLUT4 in 3T3-L1 adipocytes. Endocrinology. 147: 2245-52. PMID 16497797 DOI: 10.1210/En.2005-1638 |
0.564 |
|
| 2006 |
Lee CH, Olson P, Hevener A, Mehl I, Chong LW, Olefsky JM, Gonzalez FJ, Ham J, Kang H, Peters JM, Evans RM. PPARdelta regulates glucose metabolism and insulin sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 103: 3444-9. PMID 16492734 DOI: 10.1073/Pnas.0511253103 |
0.564 |
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| 2006 |
de Luca C, Olefsky JM. Stressed out about obesity and insulin resistance. Nature Medicine. 12: 41-2; discussion 42. PMID 16397561 DOI: 10.1038/Nm0106-41 |
0.493 |
|
| 2006 |
Neels JG, Olefsky JM. Inflamed fat: what starts the fire? The Journal of Clinical Investigation. 116: 33-5. PMID 16395402 DOI: 10.1172/Jci27280 |
0.377 |
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| 2005 |
Huang J, Imamura T, Babendure JL, Lu JC, Olefsky JM. Disruption of microtubules ablates the specificity of insulin signaling to GLUT4 translocation in 3T3-L1 adipocytes. The Journal of Biological Chemistry. 280: 42300-6. PMID 16239226 DOI: 10.1074/Jbc.M510920200 |
0.599 |
|
| 2005 |
Zhang J, Hupfeld CJ, Taylor SS, Olefsky JM, Tsien RY. Insulin disrupts beta-adrenergic signalling to protein kinase A in adipocytes. Nature. 437: 569-73. PMID 16177793 DOI: 10.1038/Nature04140 |
0.469 |
|
| 2005 |
Nguyen MT, Satoh H, Favelyukis S, Babendure JL, Imamura T, Sbodio JI, Zalevsky J, Dahiyat BI, Chi NW, Olefsky JM. JNK and tumor necrosis factor-alpha mediate free fatty acid-induced insulin resistance in 3T3-L1 adipocytes. The Journal of Biological Chemistry. 280: 35361-71. PMID 16085647 DOI: 10.1074/Jbc.M504611200 |
0.53 |
|
| 2005 |
Wilkes JJ, Nguyen MT, Bandyopadhyay GK, Nelson E, Olefsky JM. Topiramate treatment causes skeletal muscle insulin sensitization and increased Acrp30 secretion in high-fat-fed male Wistar rats. American Journal of Physiology. Endocrinology and Metabolism. 289: E1015-22. PMID 16030065 DOI: 10.1152/Ajpendo.00169.2005 |
0.544 |
|
| 2005 |
Usui I, Imamura T, Babendure JL, Satoh H, Lu JC, Hupfeld CJ, Olefsky JM. G protein-coupled receptor kinase 2 mediates endothelin-1-induced insulin resistance via the inhibition of both Galphaq/11 and insulin receptor substrate-1 pathways in 3T3-L1 adipocytes. Molecular Endocrinology (Baltimore, Md.). 19: 2760-8. PMID 15994203 DOI: 10.1210/Me.2004-0429 |
0.581 |
|
| 2005 |
Li LS, Babendure JL, Sinha SC, Olefsky JM, Lerner RA. Synthesis and evaluation of photolabile insulin prodrugs. Bioorganic & Medicinal Chemistry Letters. 15: 3917-20. PMID 15993597 DOI: 10.1016/J.Bmcl.2005.05.112 |
0.616 |
|
| 2005 |
Satoh H, Nguyen MT, Trujillo M, Imamura T, Usui I, Scherer PE, Olefsky JM. Adenovirus-mediated adiponectin expression augments skeletal muscle insulin sensitivity in male Wistar rats. Diabetes. 54: 1304-13. PMID 15855314 DOI: 10.2337/Diabetes.54.5.1304 |
0.632 |
|
| 2005 |
Bard-Chapeau EA, Hevener AL, Long S, Zhang EE, Olefsky JM, Feng GS. Deletion of Gab1 in the liver leads to enhanced glucose tolerance and improved hepatic insulin action. Nature Medicine. 11: 567-71. PMID 15821749 DOI: 10.1038/Nm1227 |
0.627 |
|
| 2005 |
Goodarzi MO, Taylor KD, Guo X, Quiñones MJ, Cui J, Li X, Hang T, Yang H, Holmes E, Hsueh WA, Olefsky J, Rotter JI. Variation in the Gene for Muscle-Specific AMP Deaminase Is Associated With Insulin Clearance, a Highly Heritable Trait Diabetes. 54: 1222-1227. PMID 15793265 DOI: 10.2337/Diabetes.54.4.1222 |
0.632 |
|
| 2005 |
Arkan MC, Hevener AL, Greten FR, Maeda S, Li ZW, Long JM, Wynshaw-Boris A, Poli G, Olefsky J, Karin M. IKK-beta links inflammation to obesity-induced insulin resistance. Nature Medicine. 11: 191-8. PMID 15685170 DOI: 10.1038/Nm1185 |
0.575 |
|
| 2005 |
Wilkes JJ, Nelson E, Osborne M, Demarest KT, Olefsky JM. Topiramate is an insulin-sensitizing compound in vivo with direct effects on adipocytes in female ZDF rats. American Journal of Physiology. Endocrinology and Metabolism. 288: E617-24. PMID 15536205 DOI: 10.1152/Ajpendo.00437.2004 |
0.62 |
|
| 2005 |
Hupfeld CJ, Resnik JL, Ugi S, Olefsky JM. Insulin-induced β-Arrestin1 Ser-412 Phosphorylation Is a Mechanism for Desensitization of ERK Activation by Gαi-coupled Receptors Journal of Biological Chemistry. 280: 1016-1023. PMID 15520010 DOI: 10.1074/Jbc.M403674200 |
0.529 |
|
| 2005 |
Sharma PM, Son H, Ugi S, Ricketts W, Olefsky JM. Mechanism of SHIP-mediated inhibition of insulin- and platelet-derived growth factor-stimulated mitogen-activated protein kinase activity in 3T3-L1 adipocytes. Molecular Endocrinology. 19: 421-430. PMID 15486046 DOI: 10.1210/Me.2004-0096 |
0.573 |
|
| 2004 |
Usui I, Imamura T, Huang J, Satoh H, Shenoy SK, Lefkowitz RJ, Hupfeld CJ, Olefsky JM. beta-arrestin-1 competitively inhibits insulin-induced ubiquitination and degradation of insulin receptor substrate 1. Molecular and Cellular Biology. 24: 8929-37. PMID 15456867 DOI: 10.1128/Mcb.24.20.8929-8937.2004 |
0.513 |
|
| 2004 |
Ugi S, Imamura T, Maegawa H, Egawa K, Yoshizaki T, Shi K, Obata T, Ebina Y, Kashiwagi A, Olefsky JM. Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes. Molecular and Cellular Biology. 24: 8778-89. PMID 15367694 DOI: 10.1128/Mcb.24.19.8778-8789.2004 |
0.509 |
|
| 2004 |
Wiedmer T, Zhao J, Li L, Zhou Q, Hevener A, Olefsky JM, Curtiss LK, Sims PJ. Adiposity, dyslipidemia, and insulin resistance in mice with targeted deletion of phospholipid scramblase 3 (PLSCR3). Proceedings of the National Academy of Sciences of the United States of America. 101: 13296-301. PMID 15328404 DOI: 10.1073/Pnas.0405354101 |
0.473 |
|
| 2004 |
Satoh H, Nguyen MT, Miles PD, Imamura T, Usui I, Olefsky JM. Adenovirus-mediated chronic "hyper-resistinemia" leads to in vivo insulin resistance in normal rats. The Journal of Clinical Investigation. 114: 224-31. PMID 15254589 DOI: 10.1172/Jci20785 |
0.657 |
|
| 2004 |
Usui I, Imamura T, Satoh H, Huang J, Babendure JL, Hupfeld CJ, Olefsky JM. GRK2 is an endogenous protein inhibitor of the insulin signaling pathway for glucose transport stimulation. The Embo Journal. 23: 2821-9. PMID 15241473 DOI: 10.1038/Sj.Emboj.7600297 |
0.609 |
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| 2004 |
Hsiao A, Worrall DS, Olefsky JM, Subramaniam S. Variance-modeled posterior inference of microarray data: detecting gene-expression changes in 3T3-L1 adipocytes. Bioinformatics (Oxford, England). 20: 3108-27. PMID 15217816 DOI: 10.1093/Bioinformatics/Bth371 |
0.362 |
|
| 2004 |
Koo SH, Satoh H, Herzig S, Lee CH, Hedrick S, Kulkarni R, Evans RM, Olefsky J, Montminy M. PGC-1 promotes insulin resistance in liver through PPAR-alpha-dependent induction of TRB-3. Nature Medicine. 10: 530-4. PMID 15107844 DOI: 10.1038/Nm1044 |
0.581 |
|
| 2004 |
Yoshizaki T, Maegawa H, Egawa K, Ugi S, Nishio Y, Imamura T, Kobayashi T, Tamura S, Olefsky JM, Kashiwagi A. Protein phosphatase-2C alpha as a positive regulator of insulin sensitivity through direct activation of phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. The Journal of Biological Chemistry. 279: 22715-26. PMID 15016818 DOI: 10.1074/jbc.M313745200 |
0.472 |
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| 2004 |
Huang J, Hsia SH, Imamura T, Usui I, Olefsky JM. Annexin II is a thiazolidinedione-responsive gene involved in insulin-induced glucose transporter isoform 4 translocation in 3T3-L1 adipocytes. Endocrinology. 145: 1579-1586. PMID 14726447 DOI: 10.1210/En.2003-1197 |
0.546 |
|
| 2004 |
Pajvani UB, Hawkins M, Combs TP, Rajala MW, Doebber T, Berger JP, Wagner JA, Wu M, Knopps A, Xiang AH, Utzschneider KM, Kahn SE, Olefsky JM, Buchanan TA, Scherer PE. Complex distribution, not absolute amount of adiponectin, correlates with thiazolidinedione-mediated improvement in insulin sensitivity. The Journal of Biological Chemistry. 279: 12152-62. PMID 14699128 DOI: 10.1074/Jbc.M311113200 |
0.582 |
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| 2004 |
Pillay TS, Xiao S, Keranen L, Olefsky JM. Regulation of the insulin receptor by protein kinase C isoenzymes: preferential interaction with beta isoenzymes and interaction with the catalytic domain of betaII. Cellular Signalling. 16: 97-104. PMID 14607280 DOI: 10.1016/S0898-6568(03)00090-1 |
0.611 |
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| 2004 |
Koo S, Satoh H, Herzig S, Lee C, Hedrick S, Kulkarni R, Evans RM, Olefsky J, Montminy M. Erratum: PGC-1 promotes insulin resistance in liver through PPAR-α-dependent induction of TRB-3 Nature Medicine. 10: 755-755. DOI: 10.1038/Nm0704-755A |
0.499 |
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| 2003 |
He W, Barak Y, Hevener A, Olson P, Liao D, Le J, Nelson M, Ong E, Olefsky JM, Evans RM. Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle. Proceedings of the National Academy of Sciences of the United States of America. 100: 15712-7. PMID 14660788 DOI: 10.1073/Pnas.2536828100 |
0.596 |
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| 2003 |
Hevener AL, He W, Barak Y, Le J, Bandyopadhyay G, Olson P, Wilkes J, Evans RM, Olefsky J. Muscle-specific Pparg deletion causes insulin resistance. Nature Medicine. 9: 1491-7. PMID 14625542 DOI: 10.1038/Nm956 |
0.573 |
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| 2003 |
Xie L, Lee SY, Andersen JN, Waters S, Shen K, Guo XL, Moller NP, Olefsky JM, Lawrence DS, Zhang ZY. Cellular effects of small molecule PTP1B inhibitors on insulin signaling. Biochemistry. 42: 12792-804. PMID 14596593 DOI: 10.1021/Bi035238P |
0.636 |
|
| 2003 |
Wilkes JJ, Hevener A, Olefsky J. Chronic Endothelin-1 Treatment Leads to Insulin Resistance In Vivo Diabetes. 52: 1904-1909. PMID 12882904 DOI: 10.2337/Diabetes.52.8.1904 |
0.581 |
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| 2003 |
Imamura T, Huang J, Usui I, Satoh H, Bever J, Olefsky JM. Insulin-induced GLUT4 translocation involves protein kinase C-lambda-mediated functional coupling between Rab4 and the motor protein kinesin. Molecular and Cellular Biology. 23: 4892-900. PMID 12832475 DOI: 10.1128/Mcb.23.14.4892-4900.2003 |
0.594 |
|
| 2003 |
Yu JG, Boies SM, Olefsky JM. The effect of oral glucosamine sulfate on insulin sensitivity in human subjects. Diabetes Care. 26: 1941-2. PMID 12766141 DOI: 10.2337/Diacare.26.6.1941 |
0.633 |
|
| 2003 |
Lee B, Miles PD, Vargas L, Luan P, Glasco S, Kushnareva Y, Kornbrust ES, Grako KA, Wollheim CB, Maechler P, Olefsky JM, Anderson CM. Inhibition of mitochondrial Na+-Ca2+ exchanger increases mitochondrial metabolism and potentiates glucose-stimulated insulin secretion in rat pancreatic islets. Diabetes. 52: 965-73. PMID 12663468 DOI: 10.2337/Diabetes.52.4.965 |
0.55 |
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| 2003 |
Kruszynska YT, Olefsky JM, Frias JP. Effect of obesity on susceptibility to fatty acid-induced peripheral tissue insulin resistance Metabolism: Clinical and Experimental. 52: 233-238. PMID 12601639 DOI: 10.1053/Meta.2003.50029 |
0.534 |
|
| 2003 |
Usui I, Imamura T, Huang J, Satoh H, Olefsky JM. Cdc42 is a Rho GTPase family member that can mediate insulin signaling to glucose transport in 3T3-L1 adipocytes. The Journal of Biological Chemistry. 278: 13765-74. PMID 12566459 DOI: 10.1074/Jbc.M208904200 |
0.561 |
|
| 2003 |
Miles PD, Barak Y, Evans RM, Olefsky JM. Effect of heterozygous PPARgamma deficiency and TZD treatment on insulin resistance associated with age and high-fat feeding. American Journal of Physiology. Endocrinology and Metabolism. 284: E618-26. PMID 12556354 DOI: 10.1152/Ajpendo.00312.2002 |
0.54 |
|
| 2003 |
Hupfeld CJ, Dalle S, Olefsky JM. β-arrestin 1 down-regulation after insulin treatment is associated with supersensitization of β2 adrenergic receptor Gαs signaling in 3T3-L1 adipocytes Proceedings of the National Academy of Sciences of the United States of America. 100: 161-166. PMID 12509508 DOI: 10.1073/Pnas.0235674100 |
0.462 |
|
| 2002 |
Ruan H, Miles PD, Ladd CM, Ross K, Golub TR, Olefsky JM, Lodish HF. Profiling gene transcription in vivo reveals adipose tissue as an immediate target of tumor necrosis factor-alpha: implications for insulin resistance. Diabetes. 51: 3176-88. PMID 12401708 DOI: 10.2337/Diabetes.51.11.3176 |
0.427 |
|
| 2002 |
Yu JG, Javorschi S, Hevener AL, Kruszynska YT, Norman RA, Sinha M, Olefsky JM. The Effect of Thiazolidinediones on Plasma Adiponectin Levels in Normal, Obese, and Type 2 Diabetic Subjects Diabetes. 51: 2968-2974. PMID 12351435 DOI: 10.2337/Diabetes.51.10.2968 |
0.494 |
|
| 2002 |
Dalle S, Imamura T, Rose DW, Worrall DS, Ugi S, Hupfeld CJ, Olefsky JM. Insulin Induces Heterologous Desensitization of G Protein-Coupled Receptor and Insulin-Like Growth Factor I Signaling by Downregulating β-Arrestin-1 Molecular and Cellular Biology. 22: 6272-6285. PMID 12167719 DOI: 10.1128/Mcb.22.17.6272-6285.2002 |
0.409 |
|
| 2002 |
Hevener A, Reichart D, Janez A, Olefsky J. Female rats do not exhibit free fatty acid-induced insulin resistance. Diabetes. 51: 1907-1912. PMID 12031980 DOI: 10.2337/Diabetes.51.6.1907 |
0.615 |
|
| 2002 |
Ugi S, Sharma PM, Ricketts W, Imamura T, Olefsky JM. Phosphatidylinositol 3-kinase is required for insulin-stimulated tyrosine phosphorylation of Shc in 3T3-L1 adipocytes. Journal of Biological Chemistry. 277: 18592-18597. PMID 11897789 DOI: 10.1074/Jbc.M201019200 |
0.522 |
|
| 2002 |
Ugi S, Imamura T, Ricketts W, Olefsky JM. Protein Phosphatase 2A Forms a Molecular Complex with Shc and Regulates Shc Tyrosine Phosphorylation and Downstream Mitogenic Signaling Molecular and Cellular Biology. 22: 2375-2387. PMID 11884620 DOI: 10.1128/Mcb.22.7.2375-2387.2002 |
0.438 |
|
| 2002 |
Worrall DS, Olefsky JM. The effects of intracellular calcium depletion on insulin signaling in 3T3-L1 adipocytes Molecular Endocrinology. 16: 378-389. PMID 11818508 DOI: 10.1210/Mend.16.2.0776 |
0.626 |
|
| 2002 |
Kruszynska YT, Worrall DS, Ofrecio J, Frias JP, Macaraeg G, Olefsky JM. Fatty Acid-Induced Insulin Resistance: Decreased Muscle PI3K Activation But Unchanged Akt Phosphorylation The Journal of Clinical Endocrinology and Metabolism. 87: 226-234. PMID 11788651 DOI: 10.1210/Jcem.87.1.8187 |
0.477 |
|
| 2002 |
Barak Y, Liao D, He W, Ong ES, Nelson MC, Olefsky JM, Boland R, Evans RM. Effects of peroxisome proliferator-activated receptor delta on placentation, adiposity, and colorectal cancer. Proceedings of the National Academy of Sciences of the United States of America. 99: 303-8. PMID 11756685 DOI: 10.1073/Pnas.012610299 |
0.32 |
|
| 2001 |
Worrall DS, McDunn JE, List B, Reichart D, Hevener A, Gustafson T, Barbas CF, Lerner RA, Olefsky JM. Synthesis of an organoinsulin molecule that can be activated by antibody catalysis. Proceedings of the National Academy of Sciences of the United States of America. 98: 13514-8. PMID 11707596 DOI: 10.1073/Pnas.241516698 |
0.634 |
|
| 2001 |
Huang J, Imamura T, Olefsky JM. Insulin can regulate GLUT4 internalization by signaling to Rab5 and the motor protein dynein Proceedings of the National Academy of Sciences of the United States of America. 98: 13084-13089. PMID 11687655 DOI: 10.1073/Pnas.241368698 |
0.614 |
|
| 2001 |
Hevener AL, Reichart D, Janez A, Olefsky J. Thiazolidinedione Treatment Prevents Free Fatty Acid–Induced Insulin Resistance in Male Wistar Rats Diabetes. 50: 2316-2322. PMID 11574414 DOI: 10.2337/Diabetes.50.10.2316 |
0.588 |
|
| 2001 |
Imamura T, Huang J, Dalle S, Ugi S, Usui I, Luttrell LM, Miller WE, Lefkowitz RJ, Olefsky JM. beta -Arrestin-mediated recruitment of the Src family kinase Yes mediates endothelin-1-stimulated glucose transport. The Journal of Biological Chemistry. 276: 43663-7. PMID 11546805 DOI: 10.1074/Jbc.M105364200 |
0.432 |
|
| 2001 |
Frias JP, Macaraeg GB, Ofrecio J, Yu JG, Olefsky JM, Kruszynska YT. Decreased Susceptibility to Fatty Acid–Induced Peripheral Tissue Insulin Resistance in Women Diabetes. 50: 1344-1350. PMID 11375335 DOI: 10.2337/Diabetes.50.6.1344 |
0.521 |
|
| 2001 |
Ishibashi K, Imamura T, Sharma PM, Huang J, Ugi S, Olefsky JM. Chronic endothelin-1 treatment leads to heterologous desensitization of insulin signaling in 3T3-L1 adipocytes Journal of Clinical Investigation. 107: 1193-1202. PMID 11342583 DOI: 10.1172/Jci11753 |
0.568 |
|
| 2001 |
Dalle S, Ricketts W, Imamura T, Vollenweider P, Olefsky JM. Insulin and insulin-like growth factor I receptors utilize different G protein signaling components. Journal of Biological Chemistry. 276: 15688-15695. PMID 11278773 DOI: 10.1074/Jbc.M010884200 |
0.599 |
|
| 2001 |
Goalstone ML, Leitner JW, Berhanu P, Sharma PM, Olefsky JM, Draznin B. Insulin signals to prenyltransferases via the Shc branch of intracellular signaling. Journal of Biological Chemistry. 276: 12805-12812. PMID 11278505 DOI: 10.1074/Jbc.M009443200 |
0.623 |
|
| 2001 |
Miles PD, Higo K, Olefsky JM. Exercise-stimulated glucose turnover in the rat is impaired by glucosamine infusion. Diabetes. 50: 139-42. PMID 11147779 DOI: 10.2337/Diabetes.50.1.139 |
0.434 |
|
| 2000 |
Ishibashi KI, Imamura T, Sharma PM, Ugi S, Olefsky JM. The Acute and Chronic Stimulatory Effects of Endothelin-1 on Glucose Transport Are Mediated by Distinct Pathways in 3T3-L1 Adipocytes* *This work was supported by NIH Grant DK-33651. Endocrinology. 141: 4623-4628. PMID 28201052 DOI: 10.1210/Endo.141.12.7820 |
0.409 |
|
| 2000 |
Janez A, Worrall DS, Olefsky JM. Insulin-Mediated Cellular Insulin Resistance Decreases Osmotic Shock-Induced Glucose Transport in 3T3-L1 Adipocytes* *This work was supported by NIH Grant DK-33651 and the Veterans Administration Medical Research Service. Andrej Janez was supported by a grant from Slovenian Ministry of Science and Technology (sklad za mlade raziskovalce). Endocrinology. 141: 4657-4663. PMID 28201043 DOI: 10.1210/Endo.141.12.7801 |
0.643 |
|
| 2000 |
Hevener AL, Reichart D, Olefsky J. Exercise and thiazolidinedione therapy normalize insulin action in the obese Zucker fatty rat. Diabetes. 49: 2154-2159. PMID 11118020 DOI: 10.2337/Diabetes.49.12.2154 |
0.476 |
|
| 2000 |
Olefsky JM. Diabetes: Gene therapy for rats and mice Nature. 408: 420-421. PMID 11100710 DOI: 10.1038/35044177 |
0.437 |
|
| 2000 |
Olefsky JM, Saltiel AR. PPAR gamma and the treatment of insulin resistance. Trends in Endocrinology and Metabolism: Tem. 11: 362-8. PMID 11042466 DOI: 10.1016/S1043-2760(00)00306-4 |
0.605 |
|
| 2000 |
Olefsky JM. Treatment of insulin resistance with peroxisome proliferator-activated receptor γ agonists Journal of Clinical Investigation. 106: 467-472. PMID 10953021 DOI: 10.1172/Jci10843 |
0.606 |
|
| 2000 |
Kruszynska YT, Yu JG, Olefsky JM, Sobel BE. Effects of troglitazone on blood concentrations of plasminogen activator inhibitor 1 in patients with type 2 diabetes and in lean and obese normal subjects. Diabetes. 49: 633-9. PMID 10871202 DOI: 10.2337/Diabetes.49.4.633 |
0.549 |
|
| 2000 |
Frias JP, Yu JG, Kruszynska YT, Olefsky JM. Metabolic effects of troglitazone therapy in type 2 diabetic, obese, and lean normal subjects. Diabetes Care. 23: 64-69. PMID 10857970 DOI: 10.2337/Diacare.23.1.64 |
0.554 |
|
| 2000 |
Haruta T, Uno T, Kawahara J, Takano A, Egawa K, Sharma PM, Olefsky JM, Kobayashi M. A rapamycin-sensitive pathway down-regulates insulin signaling via phosphorylation and proteasomal degradation of insulin receptor substrate-1. Molecular Endocrinology (Baltimore, Md.). 14: 783-94. PMID 10847581 DOI: 10.1210/Mend.14.6.0446 |
0.617 |
|
| 2000 |
Janez A, Worrall DS, Imamura T, Sharma PM, Olefsky JM. The osmotic shock-induced glucose transport pathway in 3T3-L1 adipocytes is mediated by gab-1 and requires Gab-1-associated phosphatidylinositol 3-kinase activity for full activation. Journal of Biological Chemistry. 275: 26870-26876. PMID 10842168 DOI: 10.1074/Jbc.M001654200 |
0.487 |
|
| 2000 |
Egawa K, Nakashima N, Sharma PM, Maegawa H, Nagai Y, Kashiwagi A, Kikkawa R, Olefsky JM. Persistent activation of phosphatidylinositol 3-kinase causes insulin resistance due to accelerated insulin-induced insulin receptor substrate-1 degradation in 3T3-L1 adipocytes. Endocrinology. 141: 1930-1935. PMID 10830273 DOI: 10.1210/Endo.141.6.7516 |
0.628 |
|
| 2000 |
Nakashima N, Sharma PM, Imamura T, Bookstein R, Olefsky JM. The Tumor Suppressor PTEN Negatively Regulates Insulin Signaling in 3T3-L1 Adipocytes Journal of Biological Chemistry. 275: 12889-12895. PMID 10777587 DOI: 10.1074/Jbc.275.17.12889 |
0.582 |
|
| 2000 |
Draznin B, Miles P, Kruszynska Y, Olefsky J, Friedman J, Golovchenko I, Stjernholm R, Wall K, Reitman M, Accili D, Cooksey R, McClain D, Goalstone M. Effects of insulin on prenylation as a mechanism of potentially detrimental influence of hyperinsulinemia. Endocrinology. 141: 1310-6. PMID 10746633 DOI: 10.1210/Endo.141.4.7411 |
0.627 |
|
| 2000 |
Miles PD, Barak Y, He W, Evans RM, Olefsky JM. Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency. The Journal of Clinical Investigation. 105: 287-92. PMID 10675354 DOI: 10.1172/Jci8538 |
0.589 |
|
| 2000 |
Janez A, Worrall DS, Olefsky JM. Insulin-Mediated Cellular Insulin Resistance Decreases Osmotic Shock-Induced Glucose Transport in 3T3-L1 Adipocytes* Endocrinology. 141: 4657-4663. DOI: 10.1210/En.141.12.4657 |
0.642 |
|
| 2000 |
Janez A, Sears-Worrall D, Olefsky JM. Cellular insulin resistance decreases osmotic shock-induced glucose transport in 3T3-L1 adipocytes Diabetes Research and Clinical Practice. 50: 158. DOI: 10.1016/S0168-8227(00)81996-8 |
0.554 |
|
| 2000 |
Ishibashi K, Imamura T, Sharma PM, Ugi S, Olefsky JM. Chronic endothelin-1 treatment leads to heterologous desensitization of insulin signaling in 3T3-L1 adipocytes Diabetes Research and Clinical Practice. 50: 158. DOI: 10.1016/S0168-8227(00)81995-6 |
0.479 |
|
| 2000 |
Ishibashi K, Imamura T, Sharma PM, Ugi S, Olefsky JM. The acute and chronic stimulatory effects of endothelin-1 on glucose transport are mediated by distinct pathways in 3T3-L1 adipocytes Diabetes Research and Clinical Practice. 50: 157. DOI: 10.1016/S0168-8227(00)81992-0 |
0.379 |
|
| 1999 |
Ricketts WA, Brown JH, Olefsky JM. Pertussis toxin-sensitive and -insensitive thrombin stimulation of Shc phosphorylation and mitogenesis are mediated through distinct pathways. Molecular Endocrinology. 13: 1988-2001. PMID 10598576 DOI: 10.1210/Mend.13.12.0385 |
0.311 |
|
| 1999 |
Yu JG, Kruszynska YT, Mulford MI, Olefsky JM. A comparison of troglitazone and metformin on insulin requirements in euglycemic intensively insulin-treated type 2 diabetic patients. Diabetes. 48: 2414-2421. PMID 10580431 DOI: 10.2337/Diabetes.48.12.2414 |
0.642 |
|
| 1999 |
Imamura T, Ishibashi K, Dalle S, Ugi S, Olefsky JM. Endothelin-1-induced GLUT4 translocation is mediated via Galpha(q/11) protein and phosphatidylinositol 3-kinase in 3T3-L1 adipocytes. Journal of Biological Chemistry. 274: 33691-33695. PMID 10559259 DOI: 10.1074/Jbc.274.47.33691 |
0.425 |
|
| 1999 |
Zapf-Colby A, Eichhorn J, Webster NJ, Olefsky JM. Inhibition of PLC-gamma1 activity converts nerve growth factor from an anti-mitogenic to a mitogenic signal in CHO cells. Oncogene. 18: 4908-19. PMID 10490825 DOI: 10.1038/Sj.Onc.1202861 |
0.356 |
|
| 1999 |
Imamura T, Vollenweider P, Egawa K, Clodi M, Ishibashi K, Nakashima N, Ugi S, Adams JW, Brown JH, Olefsky JM. G alpha-q/11 protein plays a key role in insulin-induced glucose transport in 3T3-L1 adipocytes. Molecular and Cellular Biology. 19: 6765-6774. PMID 10490615 DOI: 10.1128/Mcb.19.10.6765 |
0.586 |
|
| 1999 |
Egawa K, Sharma PM, Nakashima N, Huang Y, Huver E, Boss GR, Olefsky JM. Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance. Journal of Biological Chemistry. 274: 14306-14314. PMID 10318852 DOI: 10.1074/Jbc.274.20.14306 |
0.574 |
|
| 1999 |
Nakashima N, Rose DW, Xiao S, Egawa K, Martin SS, Haruta T, Saltiel AR, Olefsky JM. The functional role of CrkII in actin cytoskeleton organization and mitogenesis. The Journal of Biological Chemistry. 274: 3001-8. PMID 9915838 DOI: 10.1074/Jbc.274.5.3001 |
0.678 |
|
| 1999 |
Olefsky JM. Insulin-stimulated glucose transport minireview series Journal of Biological Chemistry. 274: 1863. PMID 9890934 DOI: 10.1074/Jbc.274.4.1863 |
0.589 |
|
| 1998 |
Clodi M, Vollenweider P, Klarlund J, Nakashima N, Martin S, Czech MP, Olefsky JM. Effects of General Receptor for Phosphoinositides 1 on Insulin and Insulin-Like Growth Factor I-Induced Cytoskeletal Rearrangement, Glucose Transporter-4 Translocation, and Deoxyribonucleic Acid Synthesis* * This work was supported by Grants J 01287-Med and J 1584-Med from the Erwin Schrödinger Stipendium by the Fonds zur Förderung der wissenschaftlichen Forschung, Austria (to M.C.); a grant from the Schweizerische Stiftung für Medizinisch-Biologische Stipendien (to P.V.); and in part by NIH Grant DK-33651. Endocrinology. 139: 4984-4990. PMID 28204246 DOI: 10.1210/Endo.139.12.6351 |
0.712 |
|
| 1998 |
Rose DW, Xiao S, Pillay TS, Kolch W, Olefsky JM. Prolonged vs transient roles for early cell cycle signaling components. Oncogene. 17: 889-99. PMID 9780005 DOI: 10.1038/Sj.Onc.1201997 |
0.426 |
|
| 1998 |
Staubs PA, Nelson JG, Reichart DR, Olefsky JM. Platelet-derived growth factor inhibits insulin stimulation of insulin receptor substrate-1-associated phosphatidylinositol 3-kinase in 3T3-L1 adipocytes without affecting glucose transport. The Journal of Biological Chemistry. 273: 25139-47. PMID 9737973 DOI: 10.1074/Jbc.273.39.25139 |
0.628 |
|
| 1998 |
Ciaraldi TP, Morales AJ, Hickman MG, Odom-Ford R, Yen SSC, Olefsky JM. Lack of Insulin Resistance in Fibroblasts From Subjects With Polycystic Ovary Syndrome Metabolism-Clinical and Experimental. 47: 940-946. PMID 9711989 DOI: 10.1016/S0026-0495(98)90348-1 |
0.579 |
|
| 1998 |
Sharma PM, Egawa K, Huang Y, Martin JL, Huvar I, Boss GR, Olefsky JM. Inhibition of Phosphatidylinositol 3-Kinase Activity by Adenovirus-mediated Gene Transfer and Its Effect on Insulin Action Journal of Biological Chemistry. 273: 18528-18537. PMID 9660823 DOI: 10.1074/Jbc.273.29.18528 |
0.55 |
|
| 1998 |
Kruszynska YT, Mulford MI, Baloga J, Yu JG, Olefsky JM. Regulation of skeletal muscle hexokinase II by insulin in nondiabetic and NIDDM subjects. Diabetes. 47: 1107-1113. PMID 9648835 DOI: 10.2337/Diabetes.47.7.1107 |
0.496 |
|
| 1998 |
Kayali AG, Eichhorn J, Haruta T, Morris AJ, Nelson JG, Vollenweider P, Olefsky JM, Webster NJ. Association of the insulin receptor with phospholipase C-gamma (PLCgamma) in 3T3-L1 adipocytes suggests a role for PLCgamma in metabolic signaling by insulin. The Journal of Biological Chemistry. 273: 13808-18. PMID 9593725 DOI: 10.1074/Jbc.273.22.13808 |
0.554 |
|
| 1998 |
Miles PDG, Higo K, Romeo OM, Lee M-, Rafaat K, Olefsky JM. Troglitazone prevents hyperglycemia-induced but not glucosamine-induced insulin resistance. Diabetes. 47: 395-400. PMID 9519745 DOI: 10.2337/Diabetes.47.3.395 |
0.572 |
|
| 1998 |
He W, Rose DW, Olefsky JM, Gustafson TA. Grb10 interacts differentially with the insulin receptor, insulin-like growth factor I receptor, and epidermal growth factor receptor via the Grb10 Src homology 2 (SH2) domain and a second novel domain located between the pleckstrin homology and SH2 domains. The Journal of Biological Chemistry. 273: 6860-7. PMID 9506989 DOI: 10.1074/Jbc.273.12.6860 |
0.379 |
|
| 1998 |
Maggs DG, Buchanan TA, Burant CF, Cline G, Gumbiner B, Hsueh WA, Inzucchi S, Kelley D, Nolan J, Olefsky JM, Polonsky KS, Silver D, Valiquett TR, Shulman GI. Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus. A randomized, double-blind, placebo-controlled trial. Annals of Internal Medicine. 128: 176-85. PMID 9454525 DOI: 10.7326/0003-4819-128-3-199802010-00002 |
0.432 |
|
| 1998 |
Kruszynska YT, Mukherjee R, Jow L, Dana S, Paterniti JR, Olefsky JM. Skeletal muscle peroxisome proliferator- activated receptor-gamma expression in obesity and non- insulin-dependent diabetes mellitus. Journal of Clinical Investigation. 101: 543-548. PMID 9449686 DOI: 10.1172/Jci1076 |
0.537 |
|
| 1998 |
Miles PDG, Li S, Hart M, Romeo O, Cheng J, Cohen A, Raafat K, Moossa AR, Olefsky JM. Mechanisms of insulin resistance in experimental hyperinsulinemic dogs. Journal of Clinical Investigation. 101: 202-211. PMID 9421483 DOI: 10.1172/Jci1256 |
0.625 |
|
| 1998 |
Haruta T, Morris AJ, Vollenweider P, Nelson JG, Rose DW, Mueckler M, Olefsky JM. Ligand-independent GLUT4 translocation induced by guanosine 5'-O-(3-thiotriphosphate) involves tyrosine phosphorylation. Endocrinology. 139: 358-64. PMID 9421434 DOI: 10.1210/Endo.139.1.5698 |
0.509 |
|
| 1997 |
Ludvik B, Nolan JJ, Roberts A, Baloga J, Joyce M, Bell JM, Olefsky JM. Evidence for decreased splanchnic glucose uptake after oral glucose administration in non-insulin-dependent diabetes mellitus. Journal of Clinical Investigation. 100: 2354-2361. PMID 9410915 DOI: 10.1172/Jci119775 |
0.485 |
|
| 1997 |
Sharma PM, Egawa K, Gustafson TA, Martin JL, Olefsky JM. Adenovirus-mediated overexpression of IRS-1 interacting domains abolishes insulin-stimulated mitogenesis without affecting glucose transport in 3T3-L1 adipocytes. Molecular and Cellular Biology. 17: 7386-7397. PMID 9372969 DOI: 10.1128/Mcb.17.12.7386 |
0.612 |
|
| 1997 |
Miles PDG, Romeo OM, Higo K, Cohen A, Rafaat K, Olefsky JM. TNF-alpha-induced insulin resistance in vivo and its prevention by troglitazone Diabetes. 46: 1678-1683. PMID 9356012 DOI: 10.2337/Diab.46.11.1678 |
0.5 |
|
| 1997 |
Vollenweider P, Martin SS, Haruta T, Morris AJ, Nelson JG, Cormont M, Le Marchand-Brustel Y, Rose DW, Olefsky JM. The small guanosine triphosphate-binding protein Rab4 is involved in insulin-induced GLUT4 translocation and actin filament rearrangement in 3T3-L1 cells. Endocrinology. 138: 4941-9. PMID 9348225 DOI: 10.1210/Endo.138.11.5493 |
0.749 |
|
| 1997 |
Kruszynska YT, Mulford MI, Yu JG, Armstrong DA, Olefsky JM. Effects of nonesterified fatty acids on glucose metabolism after glucose ingestion. Diabetes. 46: 1586-93. PMID 9313754 DOI: 10.2337/Diacare.46.10.1586 |
0.502 |
|
| 1997 |
Thomaseth K, Pacini G, Clodi M, Kautzky‐Willer A, Nolan JJ, Prager R, Olefsky JM, Ludvik B. Amylin release during oral glucose tolerance test. Diabetic Medicine. 14: 34. PMID 9212327 DOI: 10.1002/(Sici)1096-9136(199706)14:2+3.3.Co;2-S |
0.536 |
|
| 1997 |
Nolan JJ, Ludvik B, Baloga J, Reichart D, Olefsky JM. Mechanisms of the Kinetic Defect in Insulin Action in Obesity and NIDDM Diabetes. 46: 994-1000. PMID 9166671 DOI: 10.2337/Diab.46.6.994 |
0.537 |
|
| 1997 |
Ciaraldi TP, Morales AJ, Hickman MG, Odom-Ford R, Olefsky JM, Yen SSC. Cellular Insulin Resistance in Adipocytes from Obese Polycystic Ovary Syndrome Subjects Involves Adenosine Modulation of Insulin Sensitivity The Journal of Clinical Endocrinology and Metabolism. 82: 1421-1425. PMID 9141527 DOI: 10.1210/Jcem.82.5.3961 |
0.637 |
|
| 1997 |
Ojaniemi M, Martin SS, Dolfi F, Olefsky JM, Vuori K. The proto-oncogene product p120(cbl) links c-Src and phosphatidylinositol 3'-kinase to the integrin signaling pathway. The Journal of Biological Chemistry. 272: 3780-7. PMID 9013636 DOI: 10.1074/Jbc.272.6.3780 |
0.569 |
|
| 1997 |
Thomaseth K, Pacini G, Clodi M, Kautzky-Willer A, Nolan JJ, Prager R, Olefsky JM, Ludvik B. Amylin Release During Oral Glucose Tolerance Test: AMYLIN RELEASE DURING ORAL GLUCOSE TOLERANCE TEST Diabetic Medicine. 14. DOI: 10.1002/(Sici)1096-9136(199706)14:2+3.0.Co;2-0 |
0.387 |
|
| 1996 |
Kruszynska YT, Olefsky JM. Cellular and molecular mechanisms of non-insulin dependent diabetes mellitus Journal of Investigative Medicine. 44: 413-428. PMID 8952222 |
0.382 |
|
| 1996 |
Saltiel AR, Olefsky JM. Thiazolidinediones in the treatment of insulin resistance and type II diabetes Diabetes. 45: 1661-1669. PMID 8922349 DOI: 10.2337/Diab.45.12.1661 |
0.63 |
|
| 1996 |
Martin SS, Rose DW, Saltiel AR, Klippel A, Williams LT, Olefsky JM. Phosphatidylinositol 3-kinase is necessary and sufficient for insulin- stimulated stress fiber breakdown Endocrinology. 137: 5045-5054. PMID 8895379 DOI: 10.1210/Endo.137.11.8895379 |
0.694 |
|
| 1996 |
Sasaoka T, Ishiki M, Sawa T, Ishihara H, Takata Y, Imamura T, Usui I, Olefsky JM, Kobayashi M. Comparison of the insulin and insulin-like growth factor 1 mitogenic intracellular signaling pathways. Endocrinology. 137: 4427-4434. PMID 8828504 DOI: 10.1210/Endo.137.10.8828504 |
0.62 |
|
| 1996 |
Seely BL, Staubs PA, Reichart DR, Berhanu P, Milarski KL, Saltiel AR, Kusari J, Olefsky JM. Protein tyrosine phosphatase 1B interacts with the activated insulin receptor Diabetes. 45: 1379-1385. PMID 8826975 DOI: 10.2337/Diab.45.10.1379 |
0.593 |
|
| 1996 |
Ricketts WA, Rose DW, Shoelson S, Olefsky JM. Functional roles of the Shc phosphotyrosine binding and Src homology 2 domains in insulin and epidermal growth factor signaling Journal of Biological Chemistry. 271: 26165-26169. PMID 8824262 DOI: 10.1074/Jbc.271.42.26165 |
0.408 |
|
| 1996 |
O'Neill TJ, Rose DW, Pillay TS, Hotta K, Olefsky JM, Gustafson TA. Interaction of a GRB-IR Splice Variant (a Human GRB10 Homolog) with the Insulin and Insulin-like Growth Factor I Receptors EVIDENCE FOR A ROLE IN MITOGENIC SIGNALING Journal of Biological Chemistry. 271: 22506-22513. PMID 8798417 DOI: 10.1074/Jbc.271.37.22506 |
0.559 |
|
| 1996 |
Nolan JJ, Olefsky JM, Nyce MR, Considine RV, Caro JF. Effect of Troglitazone on Leptin Production: Studies In Vitro and in Human Subjects Diabetes. 45: 1276-1278. PMID 8772734 DOI: 10.2337/Diab.45.9.1276 |
0.567 |
|
| 1996 |
Morris AJ, Martin SS, Haruta T, Nelson JG, Vollenweider P, Gustafson TA, Mueckler M, Rose DW, Olefsky JM. Evidence for an insulin receptor substrate 1 independent insulin signaling pathway that mediates insulin-responsive glucose transporter (GLUT4) translocation. Proceedings of the National Academy of Sciences of the United States of America. 93: 8401-6. PMID 8710883 DOI: 10.1073/Pnas.93.16.8401 |
0.786 |
|
| 1996 |
Kenner KA, Anyanwu E, Olefsky JM, Kusari J. Protein-tyrosine phosphatase 1B is a negative regulator of insulin- and insulin-like growth factor-I-stimulated signaling Journal of Biological Chemistry. 271: 19810-19816. PMID 8702689 DOI: 10.1074/Jbc.271.33.19810 |
0.502 |
|
| 1996 |
Martin SS, Haruta T, Morris AJ, Klippel A, Williams LT, Olefsky JM. Activated phosphatidylinositol 3-kinase is sufficient to mediate actin rearrangement and GLUT4 translocation in 3T3-L1 adipocytes. The Journal of Biological Chemistry. 271: 17605-8. PMID 8663595 DOI: 10.1074/Jbc.271.30.17605 |
0.68 |
|
| 1996 |
Ugi S, Maegawa H, Kashiwagi A, Adachi M, Olefsky JM, Kikkawa R. Expression of Dominant Negative Mutant SHPTP2 Attenuates Phosphatidylinositol 3′-Kinase Activity via Modulation of Phosphorylation of Insulin Receptor Substrate-1 Journal of Biological Chemistry. 271: 12595-12602. PMID 8647870 DOI: 10.1074/Jbc.271.21.12595 |
0.563 |
|
| 1996 |
Kolaczynski JW, Nyce MR, Considine RV, Boden G, Nolan JJ, Henry R, Mudaliar SR, Olefsky J, Caro JF. Acute and chronic effects of insulin on leptin production in humans: Studies in vivo and in vitro. Diabetes. 45: 699-701. PMID 8621027 DOI: 10.2337/Diab.45.5.699 |
0.523 |
|
| 1996 |
Pillay TS, Xiao S, Olefsky JM. Glucose-induced phosphorylation of the insulin receptor: Functional effects and characterization of phosphorylation sites Journal of Clinical Investigation. 97: 613-620. PMID 8609215 DOI: 10.1172/Jci118457 |
0.56 |
|
| 1995 |
Langlois J, Leitner W, Medh J, Sasaoka T, Olefsky JM, Draznin B. Mechanism of activation of guanine nucleotide exchange factor by insulin. Endocrine. 3: 475-9. PMID 21153201 DOI: 10.1007/Bf02738820 |
0.628 |
|
| 1995 |
Olefsky JM, Nolan JJ. Insulin resistance and non-insulin-dependent diabetes mellitus: Cellular and molecular mechanisms American Journal of Clinical Nutrition. 61. PMID 7900697 DOI: 10.1093/Ajcn/61.4.980S |
0.673 |
|
| 1995 |
Seely BL, Reichart DR, Takata Y, Yip C, Olefsky JM. A Functional Assessment of Insulin/Insulin-Like Growth Factor-I Hybrid Receptors* Endocrinology. 136: 1635-1641. PMID 7895674 DOI: 10.1210/Endo.136.4.7895674 |
0.562 |
|
| 1995 |
Pillay TS, Sasaoka T, Olefsky JM. Insulin stimulates the tyrosine dephosphorylation of pp125 focal adhesion kinase Journal of Biological Chemistry. 270: 991-994. PMID 7836419 DOI: 10.1074/Jbc.270.3.991 |
0.59 |
|
| 1995 |
Reusch JE-, Hsieh P, Bhuripanyo P, Carel K, Leitner JW, Olefsky JM, Draznin B. Insulin inhibits nuclear phosphatase activity: requirement for the C-terminal domain of the insulin receptor Endocrinology. 136: 2464-2469. PMID 7750468 DOI: 10.1210/Endo.136.6.7750468 |
0.589 |
|
| 1995 |
Pillay TS, Langlois WJ, Olefsky JM. 3 The Genetics of Non-insulin-Dependent Diabetes Mellitus Advances in Genetics. 32: 51-98. PMID 7741025 DOI: 10.1016/S0065-2660(08)60203-5 |
0.627 |
|
| 1995 |
Ludvik B, Nolan JJ, Roberts A, Baloga J, Joyce M, Bell JM, Olefsky JM. A noninvasive method to measure splanchnic glucose uptake after oral glucose administration. Journal of Clinical Investigation. 95: 2232-2238. PMID 7738188 DOI: 10.1172/Jci117913 |
0.45 |
|
| 1995 |
Sasaoka T, Langlois WJ, Rose DW, Olefsky JM. Mechanisms of enhanced transmembrane signaling by an insulin receptor lacking a cytoplasmic β-subunit domain Journal of Biological Chemistry. 270: 10885-10892. PMID 7738028 DOI: 10.1074/Jbc.270.18.10885 |
0.629 |
|
| 1995 |
Langlois WJ, Sasaoka T, Yip CC, Olefsky JM. Functional characterization of hybrid receptors composed of a truncated insulin receptor and wild type insulin-like growth factor 1 or insulin receptors. Endocrinology. 136: 1978-1986. PMID 7720646 DOI: 10.1210/Endo.136.5.7720646 |
0.522 |
|
| 1995 |
Lee MK, Olefsky JM. Acute effects of troglitazone on in vivo insulin action in normal rats Metabolism. 44: 1166-1169. PMID 7666790 DOI: 10.1016/0026-0495(95)90010-1 |
0.612 |
|
| 1995 |
Ludvik B, Nolan JJ, Baloga J, Sacks D, Olefsky J. Effect of Obesity on Insulin Resistance in Normal Subjects and Patients With NIDDM Diabetes. 44: 1121-1125. PMID 7657038 DOI: 10.2337/Diab.44.9.1121 |
0.445 |
|
| 1995 |
Seely BL, Reichart DR, Staubs PA, Jhun BH, Hsu D, Maegawa H, Milarski KL, Saltiel AR, Olefsky JM. Localization of the insulin-like growth factor I receptor binding sites for the SH2 domain proteins p85, Syp, and GTPase activating protein Journal of Biological Chemistry. 270: 19151-19157. PMID 7642582 DOI: 10.1074/Jbc.270.32.19151 |
0.417 |
|
| 1995 |
Ciaraldi TP, Huber-Knudsen K, Hickman M, Olefsky JM. Regulation of glucose transport in cultured muscle cells by novel hypoglycemic agents. Metabolism-Clinical and Experimental. 44: 976-981. PMID 7637655 DOI: 10.1016/0026-0495(95)90092-6 |
0.491 |
|
| 1995 |
Miles PDG, Levisetti M, Reichart D, Khoursheed M, Moossa AR, Olefsky JM. Kinetics of Insulin Action In Vivo: Identification of Rate-Limiting Steps Diabetes. 44: 947-953. PMID 7622001 DOI: 10.2337/Diab.44.8.947 |
0.54 |
|
| 1995 |
Jhun BH, Haruta T, Meinkoth JL, Leitner JW, Draznin B, Saltiel AR, Pang L, Sasaoka T, Olefsky JM. Signal transduction pathways leading to insulin-induced early gene induction Biochemistry. 34: 7996-8004. PMID 7540866 DOI: 10.1021/Bi00025A005 |
0.575 |
|
| 1995 |
Haruta T, Morris AJ, Rose DW, Nelson JG, Mueckler M, Olefsky JM. Insulin-stimulated GLUT4 translocation is mediated by a divergent intracellular signaling pathway. The Journal of Biological Chemistry. 270: 27991-4. PMID 7499278 DOI: 10.1074/Jbc.270.47.27991 |
0.61 |
|
| 1995 |
Khoursheed M, Miles PDG, Gao K, Lee M, Moossa AR, Olefsky JM. Metabolic effects of troglitazone on fat-induced insulin resistance in the rat Metabolism-Clinical and Experimental. 44: 1489-1494. PMID 7476339 DOI: 10.1016/0026-0495(95)90151-5 |
0.579 |
|
| 1994 |
Hsu D, Knudson PE, Zapf A, Rolband GC, Olefsky JM. NPXY motif in the insulin-like growth factor-I receptor is required for efficient ligand-mediated receptor internalization and biological signaling. Endocrinology. 134: 744-50. PMID 8299569 DOI: 10.1210/Endo.134.2.8299569 |
0.449 |
|
| 1994 |
Rose DW, Saltiel AR, Majumdar M, Decker SJ, Olefsky JM. Insulin receptor substrate 1 is required for insulin-mediated mitogenic signal transduction Proceedings of the National Academy of Sciences of the United States of America. 91: 797-801. PMID 8290602 DOI: 10.1073/Pnas.91.2.797 |
0.622 |
|
| 1994 |
Freidenberg GR, Suter S, Henry RR, Nolan J, Reichart D, Olefsky JM. Delayed Onset of Insulin Activation of the Insulin Receptor Kinase In Vivo in Human Skeletal Muscle Diabetes. 43: 118-126. PMID 8262308 DOI: 10.2337/Diab.43.1.118 |
0.647 |
|
| 1994 |
Zapf A, Hsu D, Olefsky JM. Comparison of the intracellular itineraries of insulin-like growth factor-I and insulin and their receptors in Rat-1 fibroblasts. Endocrinology. 134: 2445-52. PMID 8194471 DOI: 10.1210/Endo.134.6.8194471 |
0.618 |
|
| 1994 |
Ciaraldi TP, Kettel M, El-Roiey A, Madar Z, Reichart D, Yen SSC, Olefsky JM. Mechanisms of cellular insulin resistance in human pregnancy American Journal of Obstetrics and Gynecology. 170: 635-641. PMID 8116725 DOI: 10.1016/S0002-9378(94)70241-1 |
0.64 |
|
| 1994 |
Nolan JJ, Freidenberg G, Henry R, Reichart D, Olefsky JM. Role of human skeletal muscle insulin receptor kinase in the in vivo insulin resistance of noninsulin-dependent diabetes mellitus and obesity The Journal of Clinical Endocrinology and Metabolism. 78: 471-477. PMID 8106637 DOI: 10.1210/Jcem.78.2.8106637 |
0.584 |
|
| 1994 |
Langlois WJ, Medh J, Leitner JW, Sasaoka T, Olefsky JM, Draznin B. Insulin and epidermal growth factor influence guanine nucleotide-releasing factor by distinct mechanisms. Endocrinology. 135: 2412-7. PMID 7988425 DOI: 10.1210/Endo.135.6.7988425 |
0.507 |
|
| 1994 |
Lee M, Miles PDG, Khoursheed M, Gao K, Moossa AR, Olefsky JM. Metabolic effects of troglitazone on fructose-induced insulin resistance in the rat. Diabetes. 43: 1435-1439. PMID 7958495 DOI: 10.2337/Diab.43.12.1435 |
0.563 |
|
| 1994 |
Nolan JJ, Ludvik B, Beerdsen P, Joyce M, Olefsky J. Improvement in glucose tolerance and insulin resistance in obese subjects treated with troglitazone. The New England Journal of Medicine. 331: 1188-1193. PMID 7935656 DOI: 10.1056/Nejm199411033311803 |
0.586 |
|
| 1994 |
Grako KA, McClain DA, Olefsky JM. Hybrid formation between endogenous mouse and transfected human tyrosine kinase-deficient (A/K1018) insulin receptors leads to decreased insulin sensitivity in 3T3-L1 adipocytes. Molecular Endocrinology (Baltimore, Md.). 8: 682-92. PMID 7935484 DOI: 10.1210/Mend.8.6.7935484 |
0.568 |
|
| 1994 |
Jhun BH, Rose DW, Seely BL, Rameh L, Cantley L, Saltiel AR, Olefsky JM. Microinjection of the SH2 domain of the 85-kilodalton subunit of phosphatidylinositol 3-kinase inhibits insulin-induced DNA synthesis and c-fos expression Molecular and Cellular Biology. 14: 7466-7475. PMID 7935461 DOI: 10.1128/Mcb.14.11.7466 |
0.575 |
|
| 1994 |
Ugi S, Maegawa H, Olefsky JM, Shigeta Y, Kashiwagi A. Src homology 2 domains of protein tyrosine phosphatase are associated in vitro with both the insulin receptor and insulin receptor substrate-1 via different phosphotyrosine motifs. Febs Letters. 340: 216-220. PMID 7510639 DOI: 10.1016/0014-5793(94)80141-X |
0.57 |
|
| 1993 |
Sasaoka T, Takata Y, Kusari J, Anderson CM, Langlois WJ, Olefsky JM. Transmembrane signaling by an insulin receptor lacking a cytoplasmic beta-subunit domain. Proceedings of the National Academy of Sciences of the United States of America. 90: 4379-4383. PMID 8506276 DOI: 10.1073/Pnas.90.10.4379 |
0.603 |
|
| 1993 |
Yip CC, Hsu H, Olefsky JM, Seely L. Preparation of insulin-like growth factor I and photoaffinity labeling of insulin-like growth factor I receptor Peptides. 14: 325-330. PMID 8483809 DOI: 10.1016/0196-9781(93)90048-L |
0.532 |
|
| 1993 |
Smith RM, Sasaoka T, Shah N, Takata Y, Kusari J, Olefsky JM, Jarett L. A truncated human insulin receptor missing the COOH-terminal 365 amino acid residues does not undergo insulin-mediated receptor migration or aggregation Endocrinology. 132: 1453-1462. PMID 8462446 DOI: 10.1210/Endo.132.4.8462446 |
0.557 |
|
| 1993 |
Rolband GC, Williams JF, Webster NJG, Olefsky JM. Deletion of the insulin receptor beta-subunit acidic domain results in enhanced metabolic signaling. Endocrinology. 133: 1437-1443. PMID 8396020 DOI: 10.1210/Endo.133.3.8396020 |
0.578 |
|
| 1993 |
Begum N, Olefsky JM, Draznin B. Mechanism of impaired metabolic signaling by a truncated human insulin receptor. Decreased activation of protein phosphatase 1 by insulin Journal of Biological Chemistry. 268: 7917-7922. PMID 8385127 |
0.57 |
|
| 1993 |
Hsu D, Olefsky JM. Effect of a major histocompatibility complex class I peptide on insulin- like growth factor-I receptor internalization and biological signaling Endocrinology. 133: 1247-1251. PMID 8365366 DOI: 10.1210/Endo.133.3.8365366 |
0.496 |
|
| 1993 |
Pilch PF, Wilkinson W, Garvey WT, Ciaraldi TP, Hueckstaedt TP, Olefsky JM. Insulin-responsive human adipocytes express two glucose transporter isoforms and target them to different vesicles Journal of Clinical Endocrinology and Metabolism. 77: 286-289. PMID 8325954 DOI: 10.1210/Jcem.77.1.8325954 |
0.533 |
|
| 1993 |
Olefsky JM. Deletion of exon 21 of the insulin receptor eliminates tyrosine kinase activity but preserves mitogenic signaling Biochemistry®. 32: 13545-13550. PMID 8257690 DOI: 10.1021/Bi00212A021 |
0.587 |
|
| 1993 |
Olefsky JM. Insulin resistance and the pathogenesis of non-insulin dependent diabetes mellitus: Cellular and molecular mechanisms Advances in Experimental Medicine and Biology. 334: 129-150. PMID 8249678 DOI: 10.1007/978-1-4615-2910-1_10 |
0.521 |
|
| 1993 |
Karnieli E, Garvey WT, Olefsky JM, Hueckstead TP, Harel C, Maianu L, Armoni M. Potential role for insulin and cycloheximide in regulating the intrinsic activity of glucose transporters in isolated rat adipocytes Endocrinology. 133: 2943-2950. PMID 8243322 DOI: 10.1210/Endo.133.6.8243322 |
0.584 |
|
| 1993 |
Kaliman P, Baron V, Alengrin F, Takata Y, Webster NJ, Olefsky JM, Van Obberghen E. The insulin receptor C-terminus is involved in regulation of the receptor kinase activity. Biochemistry. 32: 9539-44. PMID 7690586 DOI: 10.1021/Bi00088A004 |
0.423 |
|
| 1993 |
Anderson CM, Henry RR, Knudson PE, Olefsky JM, Webster NJG. Relative expression of insulin receptor isoforms does not differ in lean, obese, and noninsulin-dependent diabetes mellitus subjects. The Journal of Clinical Endocrinology and Metabolism. 76: 1380-1382. PMID 7684396 DOI: 10.1210/Jcem.76.5.7684396 |
0.564 |
|
| 1992 |
Fink RI, Wallace P, Brechtel G, Olefsky JM. Evidence that glucose transport is rate-limiting for in vivo glucose uptake. Metabolism-Clinical and Experimental. 41: 897-902. PMID 1640870 DOI: 10.1016/0026-0495(92)90174-9 |
0.558 |
|
| 1992 |
Suter SL, Nolan JJ, Wallace P, Gumbiner B, Olefsky JM. Metabolic effects of new oral hypoglycemic agent CS-045 in NIDDM subjects. Diabetes Care. 15: 193-203. PMID 1547676 DOI: 10.2337/Diacare.15.2.193 |
0.402 |
|
| 1992 |
Ciaraldi TP, El-Roeiy A, Madar Z, Reichart D, Olefsky JM, Yen SSC. Cellular mechanisms of insulin resistance in polycystic ovarian syndrome. The Journal of Clinical Endocrinology and Metabolism. 75: 577-583. PMID 1322430 DOI: 10.1210/Jcem.75.2.1322430 |
0.656 |
|
| 1992 |
Grako KA, Olefsky JM, McClain DA. Tyrosine kinase-defective insulin receptors undergo decreased endocytosis but do not affect internalization of normal endogenous insulin receptors. Endocrinology. 130: 3441-52. PMID 1317784 DOI: 10.1210/Endo.130.6.1317784 |
0.583 |
|
| 1992 |
Hsu D, Olefsky JM. Characterization of insulin-like growth factor (IGF) binding proteins and their role in modulating IGF-I action in BHK cells Journal of Biological Chemistry. 267: 25576-25582. PMID 1281161 |
0.387 |
|
| 1991 |
Ciaraldi TP, Molina JM, Olefsky JM. Insulin action kinetics in adipocytes from obese and noninsulin-dependent diabetes mellitus subjects: Identification of multiple cellular defects in glucose transport Journal of Clinical Endocrinology and Metabolism. 72: 876-882. PMID 2005215 DOI: 10.1210/Jcem-72-4-876 |
0.558 |
|
| 1991 |
Kusari J, Verma US, Buse JB, Henry RR, Olefsky JM. Analysis of the gene sequences of the insulin receptor and the insulin-sensitive glucose transporter (GLUT-4) in patients with common-type non-insulin-dependent diabetes mellitus. Journal of Clinical Investigation. 88: 1323-1330. PMID 1918382 DOI: 10.1172/Jci115437 |
0.573 |
|
| 1991 |
Klauser R, Prager R, Schernthaner G, Olefsky JM. Contribution of postprandial insulin and glucose to glucose disposal in normal and insulin-resistant obese subjects. The Journal of Clinical Endocrinology and Metabolism. 73: 758-764. PMID 1890150 DOI: 10.1210/Jcem-73-4-758 |
0.628 |
|
| 1991 |
Kassir AA, Upadhyay AK, Lim TJ, Moossa AR, Olefsky JM. Lack of effect of islet amyloid polypeptide in causing insulin resistance in conscious dogs during euglycemic clamp studies. Diabetes. 40: 998-1004. PMID 1860564 DOI: 10.2337/Diab.40.8.998 |
0.574 |
|
| 1991 |
Treadway JL, Morrison BD, Soos MA, Siddle K, Olefsky J, Ullrich A, McClain DA, Pessin JE. Transdominant inhibition of tyrosine kinase activity in mutant insulin/insulin-like growth factor I hybrid receptors. Proceedings of the National Academy of Sciences of the United States of America. 88: 214-8. PMID 1846039 DOI: 10.1073/Pnas.88.1.214 |
0.406 |
|
| 1991 |
Kusari J, Olefsky JM, Strahl C, McClain DA. Insulin-receptor cDNA sequence in NIDDM patient homozygous for insulin-receptor gene RFLP. Diabetes. 40: 249-54. PMID 1671379 DOI: 10.2337/Diab.40.2.249 |
0.6 |
|
| 1991 |
Anderson CM, Olefsky JM. Phorbol ester-mediated protein kinase C interaction with wild-type and COOH-terminal truncated insulin receptors Journal of Biological Chemistry. 266: 21760-21764. PMID 1657981 |
0.567 |
|
| 1991 |
Freidenberg GR, Suter SL, Henry RR, Reichart D, Olefsky JM. In vivo stimulation of the insulin receptor kinase in human skeletal muscle. Correlation with insulin-stimulated glucose disposal during euglycemic clamp studies. Journal of Clinical Investigation. 87: 2222-2229. PMID 1645756 DOI: 10.1172/Jci115257 |
0.639 |
|
| 1990 |
Molina JM, Baron AD, Edelman SV, Brechtel G, Wallace P, Olefsky JM. Use of a variable tracer infusion method to determine glucose turnover in humans. The American Journal of Physiology. 258: E16-23. PMID 2405697 DOI: 10.1152/Ajpendo.1990.258.1.E16 |
0.429 |
|
| 1990 |
Molina JM, Cooper GJS, Leighton B, Olefsky JM. Induction of insulin resistance in vivo by amylin and calcitonin gene-related peptide Diabetes. 39: 260-265. PMID 2227135 DOI: 10.2337/Diab.39.2.260 |
0.619 |
|
| 1990 |
Thies RS, Molina JM, Ciaraldi TP, Freidenberg GR, Olefsky JM. Insulin-Receptor Autophosphorylation and Endogenous Substrate Phosphorylation in Human Adipocytes From Control, Obese, and NIDDM Subjects Diabetes. 39: 250-259. PMID 2227134 DOI: 10.2337/Diab.39.2.250 |
0.651 |
|
| 1990 |
Maegawa H, Kobayashi M, Egawa K, McClain DA, Olefsky JM, Shigeta Y. The ligand binding characteristics of a kinase-defective A/K1018 human insulin receptor expressed in Rat 1 fibroblasts. Biochimica Et Biophysica Acta. 1053: 185-8. PMID 2200525 DOI: 10.1016/0167-4889(90)90012-3 |
0.483 |
|
| 1990 |
Laakso M, Edelman SV, Olefsky JM, Brechtel G, Wallace P, Baron AD. Kinetics of in vivo muscle insulin-mediated glucose uptake in human obesity. Diabetes. 39: 965-74. PMID 2197140 DOI: 10.2337/Diab.39.8.965 |
0.515 |
|
| 1990 |
Williams JF, Olefsky JM. Defective insulin receptor function in down-regulated HepG2 cells Endocrinology. 127: 1706-1717. PMID 2169397 DOI: 10.1210/Endo-127-4-1706 |
0.564 |
|
| 1990 |
Olefsky JM. The insulin receptor. A multifunctional protein Diabetes. 39: 1009-1016. PMID 2166696 DOI: 10.2337/Diab.39.9.1009 |
0.59 |
|
| 1990 |
Ciaraldi TP, Gilmore A, Olefsky JM, Goldberg M, Heidenreich KA. In vitro studies on the action of CS-045, a new antidiabetic agent Metabolism. 39: 1056-1062. PMID 2120548 DOI: 10.1016/0026-0495(90)90166-A |
0.489 |
|
| 1990 |
Edelman SV, Laakso M, Wallace P, Brechtel G, Olefsky JM, Baron AD. Kinetics of insulin-mediated and non-insulin-mediated glucose uptake in humans. Diabetes. 39: 955-64. PMID 1973673 DOI: 10.2337/Diab.39.8.955 |
0.513 |
|
| 1989 |
Molina JM, Ciaraldi TP, Brady D, Olefsky JM. Decreased activation rate of insulin-stimulated glucose transport in adipocytes from obese subjects. Diabetes. 38: 991-5. PMID 2666204 DOI: 10.2337/Diab.38.8.991 |
0.593 |
|
| 1989 |
Brillon DJ, Freidenberg GR, Henry RR, Olefsky JM. Mechanism of Defective Insulin-Receptor Kinase Activity in NIDDM: Evidence for Two Receptor Populations Diabetes. 38: 397-403. PMID 2465197 DOI: 10.2337/Diab.38.3.397 |
0.603 |
|
| 1988 |
Garvey WT, Huecksteadt TP, Matthaei S, Olefsky JM. Role of glucose transporters in the cellular insulin resistance of type II non-insulin-dependent diabetes mellitus Journal of Clinical Investigation. 81: 1528-1536. PMID 3366906 DOI: 10.1172/Jci113485 |
0.611 |
|
| 1988 |
Levy JR, Ullrich A, Olefsky JM. Endocytotic uptake, processing, and retroendocytosis of human biosynthetic proinsulin by rat fibroblasts transfected with the human insulin receptor gene. The Journal of Clinical Investigation. 81: 1370-7. PMID 3284910 DOI: 10.1172/Jci113465 |
0.601 |
|
| 1988 |
Levy JR, Olefsky JM. Intracellular insulin-receptor dissociation and segregation in a rat fibroblast cell line transfected with a human insulin receptor gene. The Journal of Biological Chemistry. 263: 6101-8. PMID 3283119 |
0.561 |
|
| 1988 |
Garvey WT, Olefsky JM, Rubenstein AH, Kolterman OG. Day-long integrated serum insulin and C-peptide profiles in patients with NIDDM. Correlation with urinary C-peptide excretion Diabetes. 37: 590-599. PMID 3282946 DOI: 10.2337/Diab.37.5.590 |
0.492 |
|
| 1988 |
Freidenberg GR, Reichart D, Olefsky JM, Henry RR. Reversibility of defective adipocyte insulin receptor kinase activity in non-insulin-dependent diabetes mellitus. Effect of weight loss. Journal of Clinical Investigation. 82: 1398-1406. PMID 3170749 DOI: 10.1172/Jci113744 |
0.618 |
|
| 1988 |
Olefsky JM, Garvey WT, Henry RR, Brillon D, Matthael S, Freidenberg GR. Cellular mechanisms of insulin resistance in non-insulin-dependent (type II) diabetes The American Journal of Medicine. 85: 86-105. PMID 3057897 DOI: 10.1016/0002-9343(88)90401-9 |
0.596 |
|
| 1988 |
Matthaei S, Olefsky JM, Karnieli E. Cycloheximide decreases glucose transporters in rat adipocyte plasma membranes without affecting insulin-stimulated glucose transport Biochemical Journal. 251: 491-497. PMID 3041964 DOI: 10.1042/Bj2510491 |
0.603 |
|
| 1988 |
McClain DA, Henry RR, Ullrich A, Olefsky JM. Restriction-fragment-length polymorphism in insulin-receptor gene and insulin resistance in NIDDM. Diabetes. 37: 1071-5. PMID 2899037 DOI: 10.2337/Diab.37.8.1071 |
0.581 |
|
| 1988 |
Brillon DJ, Henry RR, Klein HH, Olefsky JM, Freidenberg GR. Functional and Structural Differences in Human and Rat-Derived Insulin Receptors: Characterization of the β-Subunit Kinase Activity* Endocrinology. 123: 1837-1847. PMID 2843349 DOI: 10.1210/Endo-123-4-1837 |
0.471 |
|
| 1988 |
McClain DA, Olefsky JM. Evidence for two independent pathways of insulin-receptor internalization in hepatocytes and hepatoma cells. Diabetes. 37: 806-15. PMID 2838354 DOI: 10.2337/Diab.37.6.806 |
0.619 |
|
| 1988 |
MATTHAEI S, GARVEY W, OLEFSKY J, GRETEN H. The mechanism of cellular insulin resistance at the glucose-transport level in noninsulin-dependent diabetes mellitus Acta Endocrinologica. 117: S87. DOI: 10.1530/Acta.0.117S087 |
0.551 |
|
| 1987 |
May JM, Horuk R, Olefsky JM. Photolabeling of the adipocyte hexose carrier with an aryl azide derivative of maltose Molecular and Cellular Endocrinology. 49: 181-188. PMID 3556753 DOI: 10.1016/0303-7207(87)90211-5 |
0.449 |
|
| 1987 |
Prager R, Wallace P, Olefsky JM. Direct and indirect effects of insulin to inhibit hepatic glucose output in obese subjects Diabetes. 36: 607-611. PMID 3552793 DOI: 10.2337/Diab.36.5.607 |
0.645 |
|
| 1987 |
Klein HH, Ciaraldi TP, Freidenberg GR, Olefsky JM. Adenosine Modulates Insulin Activation of Insulin Receptor Kinase in Intact Rat Adipocytes Endocrinology. 120: 2339-2345. PMID 3552635 DOI: 10.1210/Endo-120-6-2339 |
0.657 |
|
| 1987 |
Bergman RN, Prager R, Volund A, Olefsky JM. Equivalence of the insulin sensitivity index in man derived by the minimal model method and the euglycemic glucose clamp Journal of Clinical Investigation. 79: 790-800. PMID 3546379 DOI: 10.1172/Jci112886 |
0.61 |
|
| 1987 |
Glauber HS, Henry RR, Wallace P, Frank BH, Galloway JA, Cohen RM, Olefsky JM. The effects of biosynthetic human proinsulin on carbohydrate metabolism in non-insulin-dependent diabetes mellitus New England Journal of Medicine. 316: 443-449. PMID 3543679 DOI: 10.1056/Nejm198702193160805 |
0.631 |
|
| 1987 |
Prager R, Wallace P, Olefsky JM. Hyperinsulinemia does not compensate for peripheral insulin resistance in obesity Diabetes. 36: 327-334. PMID 3542654 DOI: 10.2337/Diab.36.3.327 |
0.61 |
|
| 1987 |
Levy J, Olefsky JM. The effect of insulin concentration on retroendocytosis in isolated rat adipocytes Endocrinology. 120: 450-456. PMID 3542501 DOI: 10.1210/Endo-120-2-450 |
0.63 |
|
| 1987 |
Freidenberg GR, Henry RR, Klein HH, Reichart DR, Olefsky JM. Decreased kinase activity of insulin receptors from adipocytes of non-insulin-dependent diabetic subjects. Journal of Clinical Investigation. 79: 240-250. PMID 3540010 DOI: 10.1172/Jci112789 |
0.639 |
|
| 1987 |
Matthaei S, Olefsky JM, Horuk R. Biochemical characterization and subcellular distribution of the glucose transporter from rat brain microvessels Bba - Biomembranes. 905: 417-425. PMID 3318930 DOI: 10.1016/0005-2736(87)90471-8 |
0.536 |
|
| 1987 |
Levy JR, Olefsky JM. The trafficking and processing of insulin and insulin receptors in cultured rat hepatocytes. Endocrinology. 121: 2075-86. PMID 3315635 DOI: 10.1210/Endo-121-6-2075 |
0.612 |
|
| 1987 |
Matthaei S, Garvey WT, Horuk R, Hueckstaedt TP, Olefsky JM. Human adipocyte glucose transport system. Biochemical and functional heterogeneity of hexose carriers Journal of Clinical Investigation. 79: 703-709. PMID 3102556 DOI: 10.1172/Jci112874 |
0.459 |
|
| 1987 |
Lavelle-Jones M, Scott MH, Kolterman O, Moossa AR, Olefsky JM. Non-insulin-mediated glucose uptake predominates in postabsorptive dogs. American Journal of Physiology-Endocrinology and Metabolism. 252. PMID 2883896 DOI: 10.1152/Ajpendo.1987.252.5.E660 |
0.603 |
|
| 1987 |
Baron AD, Wallace P, Olefsky JM. In vivo regulation of non-insulin-mediated and insulin-mediated glucose uptake by epinephrine Journal of Clinical Endocrinology and Metabolism. 64: 889-895. PMID 2881942 DOI: 10.1210/Jcem-64-5-889 |
0.604 |
|
| 1987 |
Lavelle-Jones M, Scott MH, Kolterman O, Rubenstein AH, Olefsky JM, Moossa AR. Selective suppression of hepatic glucose output by human proinsulin in the dog American Journal of Physiology - Endocrinology and Metabolism. 252: 15/2. PMID 2881485 DOI: 10.1152/Ajpendo.1987.252.2.E230 |
0.578 |
|
| 1987 |
Klein HH, Freidenberg GR, Henry RR, Olefsky JM. Insulin receptor tyrosine kinase activity is reduced in type-2 (non-insulin-dependent) diabetes but not in obesity European Journal of Endocrinology. 116. DOI: 10.1530/Acta.0.114S183 |
0.597 |
|
| 1987 |
Matthaei S, Garvey WT, Olefsky JM, Marshall S, Greten H. Glucose and insulin co-regulate the glucose transport system in primary cultured adipocytes: a new mechanism of insulin resistance European Journal of Endocrinology. 116: 25. DOI: 10.1530/Acta.0.114S025 |
0.616 |
|
| 1986 |
Madar Z, Olefsky J. Effect of the alpha-glucosidase inhibitor Bay-O-1248 on the metabolic response of nondiabetic and diabetic rats to a high-carbohydrate diet. The American Journal of Clinical Nutrition. 44: 206-211. PMID 3728357 DOI: 10.1093/Ajcn/44.2.206 |
0.405 |
|
| 1986 |
Matthaei S, Horuk R, Olefsky JM. Blood-brain glucose transfer in diabetes mellitus: Decreased number of glucose transporters at blood-brain barrier Diabetes. 35: 1181-1184. PMID 3530847 DOI: 10.2337/Diab.35.10.1181 |
0.467 |
|
| 1986 |
Levy JR, Murray E, Manolagas S, Olefsky JM. Demonstration of insulin receptors and modulation of alkaline phosphatase activity by insulin in rat osteoblastic cells. Endocrinology. 119: 1786-92. PMID 3530724 DOI: 10.1210/Endo-119-4-1786 |
0.636 |
|
| 1986 |
Henry RR, Wallace P, Olefsky JM. Effects of weight loss on mechanisms of hyperglycemia in obese non-insulin-dependent diabetes mellitus Diabetes. 35: 990-998. PMID 3527829 DOI: 10.2337/Diab.35.9.990 |
0.496 |
|
| 1986 |
Prager R, Wallace P, Olefsky JM. In vivo kinetics of insulin action on peripheral glucose disposal and hepatic glucose output in normal and obese subjects Journal of Clinical Investigation. 78: 472-481. PMID 3525609 DOI: 10.1172/Jci112599 |
0.606 |
|
| 1986 |
Levy JR, Olefsky JM. Retroendocytosis of insulin in rat adipocytes. Endocrinology. 119: 572-9. PMID 3525121 DOI: 10.1210/Endo-119-2-572 |
0.44 |
|
| 1986 |
Fink RI, Wallace P, Olefsky JM. Effects of aging on glucose-mediated glucose disposal and glucose transport Journal of Clinical Investigation. 77: 2034-2041. PMID 3519685 DOI: 10.1172/Jci112533 |
0.49 |
|
| 1986 |
Glauber HS, Wallace P, Galloway J, Frank BH, Olefsky JM. The effects of proinsulin pretreatment on the combined actions of insulin and proinsulin in normal man. The Journal of Clinical Endocrinology and Metabolism. 62: 785-788. PMID 3512594 DOI: 10.1210/Jcem-62-4-785 |
0.567 |
|
| 1986 |
Ciaraldi TP, Brady D, Olefsky JM. Kinetics of biosynthetic human proinsulin action in isolated rat adipocytes. Diabetes. 35: 318-23. PMID 3512342 DOI: 10.2337/Diab.35.3.318 |
0.609 |
|
| 1986 |
Garvey WT, Olefsky JM, Marshall S. Insulin induces progressive insulin resistance in cultured rat adipocytes: Sequential effects at receptor and multiple postreceptor sites Diabetes. 35: 258-267. PMID 3512337 DOI: 10.2337/Diab.35.3.258 |
0.671 |
|
| 1986 |
Henry RR, Wiest-Kent TA, Scheaffer L, Kolterman OG, Olefsky JM. Metabolic Consequences of Very-Low-Calorie Diet Therapy in Obese Non-insulin-dependent Diabetic and Nondiabetic Subjects Diabetes. 35: 155-164. PMID 3510922 DOI: 10.2337/Diab.35.2.155 |
0.443 |
|
| 1986 |
Jochen AL, Berhanu P, Olefsky JM. Insulin internalization and degradation in adipocytes from normal and type II diabetic subjects Journal of Clinical Endocrinology and Metabolism. 62: 268-274. PMID 3510222 DOI: 10.1210/Jcem-62-2-268 |
0.643 |
|
| 1986 |
Mandarino LJ, Madar Z, Kolterman OG, Bell JM, Olefsky JM. Adipocyte glycogen synthase and pyruvate dehydrogenase in obese and type II diabetic subjects American Journal of Physiology - Endocrinology and Metabolism. 251. PMID 3094377 DOI: 10.1152/Ajpendo.1986.251.4.E489 |
0.466 |
|
| 1986 |
Klein HH, Freidenberg GR, Kladde M, Olefsky JM. Insulin activation of insulin receptor tyrosine kinase in intact rat adipocytes. An in vitro system to measure histone kinase activity of insulin receptors activated in vivo Journal of Biological Chemistry. 261: 4691-4697. PMID 3007472 |
0.564 |
|
| 1985 |
Henry RR, Scheaffer L, Olefsky JM. Glycemic effects of intensive caloric restriction and isocaloric refeeding in noninsulin-dependent diabetes mellitus Journal of Clinical Endocrinology and Metabolism. 61: 917-925. PMID 4044780 DOI: 10.1210/Jcem-61-5-917 |
0.415 |
|
| 1985 |
Freidenberg GR, Olefsky JM. Dissociation of insulin resistance and decreased insulin receptor binding in Duchenne muscular dystrophy Journal of Clinical Endocrinology and Metabolism. 60: 320-327. PMID 3965491 DOI: 10.1210/Jcem-60-2-320 |
0.623 |
|
| 1985 |
Olefsky JM. Clinical, cellular, and physiologic effects of glyburide in non-insulin-dependent diabetes mellitus The American Journal of Medicine. 79: 109-112. PMID 3931458 DOI: 10.1016/S0002-9343(85)80016-4 |
0.636 |
|
| 1985 |
Horuk R, Olefsky JM. Post binding events in insulin action Diabetes/Metabolism Reviews. 1: 59-97. PMID 3915252 DOI: 10.1002/Dmr.5610010105 |
0.538 |
|
| 1985 |
Olefsky JM, Ciaraldi TP, Kolterman OG. Mechanisms of insulin resistance in non-insulin-dependent (type II) diabetes The American Journal of Medicine. 79: 12-22. PMID 3901744 DOI: 10.1016/S0002-9343(85)80003-6 |
0.659 |
|
| 1985 |
Horuk R, Olefsky JM. Post-binding events in insulin action Molecular and Cellular Endocrinology. 42: 1-20. PMID 3896892 DOI: 10.1016/0303-7207(85)90002-4 |
0.538 |
|
| 1985 |
Garvey WT, Olefsky JM, Marshall S. Insulin receptor down-regulation is linked to an insulin-induced postreceptor defect in the glucose transport system in rat adipocytes Journal of Clinical Investigation. 76: 22-30. PMID 3894420 DOI: 10.1172/Jci111950 |
0.648 |
|
| 1985 |
Heidenreich KA, Yip CC, Frank BH, Olefsky JM. The pheparation and characterization of mono-iodinated photoreactive analogs of insulin Biochemical and Biophysical Research Communications. 126: 1138-1145. PMID 3884003 DOI: 10.1016/0006-291X(85)90304-3 |
0.558 |
|
| 1985 |
Garvey WT, Revers RR, Kolterman OG, Rubenstein AH, Olefsky JM. Modulation of insulin secretion by insulin and glucose in type II diabetes mellitus Journal of Clinical Endocrinology and Metabolism. 60: 559-568. PMID 3882736 DOI: 10.1210/Jcem-60-3-559 |
0.612 |
|
| 1985 |
Fink RI, Revers RR, Kolterman OG, Olefsky JM. The Metabolic Clearance of Insulin and the Feedback Inhibition of Insulin Secretion Are Altered with Aging Diabetes. 34: 275-280. PMID 3882495 DOI: 10.2337/Diab.34.3.275 |
0.508 |
|
| 1985 |
Garvey WT, Olefsky JM, Griffin J, Hamman RF, Kolterman OG. The effect of insulin treatment on insulin secretion and insulin action in type II diabetes mellitus Diabetes. 34: 222-234. PMID 3882489 DOI: 10.2337/Diab.34.3.222 |
0.631 |
|
| 1985 |
Klein HH, Freidenberg GR, Cordera R, Olefsky JM. Substrate specificities of insulin and epidermal growth factor receptor kinases Biochemical and Biophysical Research Communications. 127: 254-263. PMID 2983709 DOI: 10.1016/S0006-291X(85)80152-2 |
0.457 |
|
| 1985 |
Baron AD, Kolterman OG, Bell J, Mandarino LJ, Olefsky JM. Rates of noninsulin-mediated glucose uptake are elevated in Type II diabetic subjects Journal of Clinical Investigation. 76: 1782-1788. PMID 2865274 DOI: 10.1172/Jci112169 |
0.534 |
|
| 1985 |
Garvey W, Olefsky J, Griffin J, Hamman R, Kolterman O. Diabetes, Vol. 34 (3), 1985 The effect of insulin treatment on in sulin secretion and insulin action in Type II diabetes mellitus The Diabetes Educator. 11: 65-65. DOI: 10.1177/014572178501100221 |
0.514 |
|
| 1985 |
Olefsky JM. Pathogenesis of insulin resistance and hyperglycemia in non-insulin-dependent diabetes mellitus The American Journal of Medicine. 79: 1-7. DOI: 10.1016/S0002-9343(85)80001-2 |
0.575 |
|
| 1985 |
Olefsky JM, Revers RR, Prince M, Henry RR, Garvey WT, Scarlett JA, Kolterman OG. Insulin resistance in non-insulin dependent (type II) and insulin dependent (type I) diabetes mellitus. Advances in Experimental Medicine and Biology. 189: 175-205. DOI: 10.1007/978-1-4757-1850-8_11 |
0.657 |
|
| 1984 |
Fink RI, Kolterman OG, Kao M, Olefsky JM. The role of the glucose transport system in the postreceptor defect in insulin action associated with human aging Journal of Clinical Endocrinology and Metabolism. 58: 721-725. PMID 6699133 DOI: 10.1210/Jcem-58-4-721 |
0.566 |
|
| 1984 |
Kolterman OG, Gray RS, Shapiro G, Scarlett JA, Griffin J, Olefsky JM. The acute and chronic effects of sulfonylurea therapy in type II diabetic subjects Diabetes. 33: 346-354. PMID 6423429 DOI: 10.2337/Diab.33.4.346 |
0.593 |
|
| 1984 |
Kolterman OG, Olefsky JM. The impact of sulfonylurea treatment upon the mechanisms responsible for the insulin resistance in type II diabetes Diabetes Care. 7: 81-88. PMID 6376033 |
0.572 |
|
| 1984 |
Bergenstal RM, Cohen RM, Lever E, Polonsky K, Jaspan J, Blix PM, Revers R, Olefsky JM, Kolterman O, Steiner K, Cherrington A, Frank B, Galloway J, Rubenstein AH. The metabolic effects of biosynthetic human proinsulin in individuals with type I diabetes. The Journal of Clinical Endocrinology and Metabolism. 58: 973-979. PMID 6373814 DOI: 10.1210/Jcem-58-6-973 |
0.614 |
|
| 1984 |
Revers RR, Henry R, Schmeiser L, Kolterman O, Cohen R, Rubenstein A, Frank B, Galloway J, Olefsky JM. Biosynthetic human insulin and proinsulin have additive but not synergistic effects on total body glucose disposal Journal of Clinical Endocrinology and Metabolism. 58: 1094-1098. PMID 6373809 DOI: 10.1210/Jcem-58-6-1094 |
0.585 |
|
| 1984 |
Fink RI, Kolterman OG, Olefsky JM. The physiological significance of the glucose intolerance of aging. The Journals of Gerontology. 39: 273-278. PMID 6371116 DOI: 10.1093/Geronj/39.3.273 |
0.457 |
|
| 1984 |
Revers RR, Fink R, Griffin J, Olefsky JM, Kolterman OG. Influence of hyperglycemia on insulin's in vivo effects in type II diabetes. Journal of Clinical Investigation. 73: 664-672. PMID 6368585 DOI: 10.1172/Jci111258 |
0.622 |
|
| 1984 |
Revers RR, Kolterman OG, Scarlett JA, Gray RS, Olefsky JM. Lack of in vivo insulin resistance in controlled insulin-dependent, type I, diabetic patients Journal of Clinical Endocrinology and Metabolism. 58: 353-358. PMID 6363437 DOI: 10.1210/Jcem-58-2-353 |
0.586 |
|
| 1984 |
Podlecki DA, Frank BH, Olefsky JM. In Vitro Characterization of Biosynthetic Human Proinsulin Diabetes. 33: 111-118. PMID 6363165 DOI: 10.2337/Diab.33.2.111 |
0.544 |
|
| 1983 |
Kolterman OG, Prince MJ, Olefsky JM. Insulin resistance in noninsulin-dependent diabetes mellitus: Impact of sulfonylurea agents in vivo and in vitro The American Journal of Medicine. 74: 82-101. PMID 6401923 DOI: 10.1016/0002-9343(83)90655-1 |
0.652 |
|
| 1983 |
Berhanu P, Kolterman OG, Baron A, Tsai P, Olefsky JM, Brandenburg D. Insulin receptors in isolated human adipocytes. Characterization by photoaffinity labeling and evidence for internalization and cellular processing. Journal of Clinical Investigation. 72: 1958-1970. PMID 6358259 DOI: 10.1172/Jci111160 |
0.568 |
|
| 1983 |
Heidenreich KA, Berhanu P, Brandenburg D, Olefsky JM. Degradation of insulin receptors in rat adipocytes Diabetes. 32: 1001-1009. PMID 6357900 DOI: 10.2337/Diab.32.11.1001 |
0.55 |
|
| 1983 |
Green A, Frank BH, Rubenstein A, Tager H, Olefsky JM. Characteristics of binding of a low affinity, noncooperative insulin ([Leu(B25)]insulin) to IM-9 lymphocytes Endocrinology. 113: 1963-1970. PMID 6357764 DOI: 10.1210/Endo-113-6-1963 |
0.64 |
|
| 1983 |
Marshall S, Olefsky JM. Separate intracellular pathways for insulin receptor recycling and insulin degradation in isolated rat adipocytes Journal of Cellular Physiology. 117: 195-203. PMID 6355127 DOI: 10.1002/Jcp.1041170210 |
0.612 |
|
| 1983 |
Ciaraldi TP, Olefsky JM. Length of acute exposure to insulin regulates the rate of deactivation of stimulated glucose transport in isolated rat adipocytes Endocrinology. 113: 1739-1745. PMID 6354696 DOI: 10.1210/Endo-113-5-1739 |
0.647 |
|
| 1983 |
Ciaraldi TP, Olefsky JM. Effect of temperature on coupling of insulin receptors to stimulation of glucose transport in isolated rat adipocytes Metabolism. 32: 1002-1008. PMID 6350807 DOI: 10.1016/0026-0495(83)90143-9 |
0.582 |
|
| 1983 |
Podlecki DA, Frank BH, Kao M, Horikoshi H, Freidenberg G, Marshall S, Ciaraldi T, Olefsky JM. Characterization of the Receptor Binding Properties of Monoiodoinsulin Isomers and the Identification of Different Insulin Receptor Specificities in Hepatic and Extrahepatic Tissues Diabetes. 32: 697-704. PMID 6347766 DOI: 10.2337/Diab.32.8.697 |
0.43 |
|
| 1983 |
Fink RI, Kolterman OG, Griffin J, Olefsky JM. Mechanisms of insulin resistance in aging Journal of Clinical Investigation. 71: 1523-1535. PMID 6345584 DOI: 10.1172/Jci110908 |
0.622 |
|
| 1983 |
Revers RR, Kolterman OG, Olefsky JM. Relationship Between Serum Glucose Level and the Metabolic Clearance Rate of Glucose in Non-insulin-dependent Diabetes Mellitus Diabetes. 32: 627-632. PMID 6345242 DOI: 10.2337/Diab.32.7.627 |
0.594 |
|
| 1983 |
Marshall S, Podlecki DA, Olefsky JM. Low pH accelerates dissociation of receptor-bound insulin Endocrinology. 113: 37-42. PMID 6345144 DOI: 10.1210/Endo-113-1-37 |
0.583 |
|
| 1983 |
Freidenberg GF, Kao M, Olefsky JM. Insulin binding to erythrocytes incubated in vitro at physiological temperature Journal of Clinical Endocrinology and Metabolism. 57: 107-114. PMID 6343415 DOI: 10.1210/Jcem-57-1-107 |
0.623 |
|
| 1983 |
Scarlett JA, Kolterman OG, Ciaraldi TP, Kao M, Olefsky JM. Insulin treatment reverses the postreceptor defect in adipocyte 3-O-methylglucose transport in type II diabetes mellitus. The Journal of Clinical Endocrinology and Metabolism. 56: 1195-1201. PMID 6341390 DOI: 10.1210/Jcem-56-6-1195 |
0.564 |
|
| 1983 |
Massague J, Freidenberg GF, Olefsky JM, Czech MP. Parallel decreases in the expression of receptors for insulin and insulin-like growth factor I in a mutant human fibroblast line Diabetes. 32: 541-544. PMID 6313454 DOI: 10.2337/Diab.32.6.541 |
0.575 |
|
| 1982 |
Roth SI, Schedewie HK, Bier DM, Conaway HH, Olefsky J, Rubenstein A, Elders MJ. Hepatic ultrastructure in leprechaunism - Hepatic ultrastructural evidence suggesting a syndrome with defective hepatic glucose release Virchows Archiv a Pathological Anatomy and Histology. 397: 121-130. PMID 7179734 DOI: 10.1007/Bf00442383 |
0.474 |
|
| 1982 |
Berhanu P, Olefsky JM. Photoaffinity labeling of insulin receptors in viable cultured human lymphocytes. Demonstration of receptor shedding and degradation Diabetes. 31: 410-417. PMID 7152133 DOI: 10.2337/Diab.31.5.410 |
0.56 |
|
| 1982 |
Ciaraldi TP, Olefsky JM. Kinetic relationships between insulin receptor binding and effects on glucose transport in isolated rat adipocytes Biochemistry. 21: 3475-3480. PMID 7052124 DOI: 10.1021/Bi00257A034 |
0.645 |
|
| 1982 |
Berhanu P, Olefsky JM, Tsai P, Thamm P, Saunders D, Brandenburg D. Internalization and molecular processing of insulin receptors in isolated rat adipocytes Proceedings of the National Academy of Sciences of the United States of America. 79: 4069-4073. PMID 7051001 DOI: 10.1073/Pnas.79.13.4069 |
0.557 |
|
| 1982 |
Olefsky JM, Kao M. Surface binding and rates of internalization of 125I-insulin in adipocytes and IM-9 lymphocytes Journal of Biological Chemistry. 257: 8667-8673. PMID 7047524 |
0.434 |
|
| 1982 |
Olefsky JM, Marshall S, Berhanu P, Saekow M, Heidenreich K, Green A. Internalization and intracellular processing of insulin and insulin receptors in adipocytes. Metabolism: Clinical and Experimental. 31: 670-90. PMID 7045573 DOI: 10.1016/0026-0495(82)90197-4 |
0.636 |
|
| 1982 |
Ciaraldi TP, Olefsky JM. Comparison of the effects of insulin and H2O2 on adipocyte glucose transport Journal of Cellular Physiology. 110: 323-328. PMID 7045141 DOI: 10.1002/Jcp.1041100318 |
0.62 |
|
| 1982 |
Olefsky JM, Saekow M, Kroc RL. Potentiation of insulin binding and insulin action by purified porcine relaxin Annals of the New York Academy of Sciences. 200-216. PMID 7044233 DOI: 10.1111/J.1749-6632.1982.Tb18043.X |
0.647 |
|
| 1982 |
Green A, Olefsky JM. Evidence for insulin-induced internalization and degradation of insulin receptors in rat adipocytes Proceedings of the National Academy of Sciences of the United States of America. 79: 427-431. PMID 7043460 DOI: 10.1073/Pnas.79.2.427 |
0.526 |
|
| 1982 |
Gray RS, Olefsky JM. Effect of a glucosidase inhibitor on the metabolic response of diabetic rats to a high carbohydrate diet, consisting of starch and sucrose, or glucose Metabolism. 31: 88-92. PMID 7043164 DOI: 10.1016/0026-0495(82)90032-4 |
0.35 |
|
| 1982 |
Scarlett JA, Kolterman OG, Moore P, Saekow M, Insel J, Griffin J, Mako M, Rubenstein AH, Olefsky JM. Insulin resistance and diabetes due to a genetic defect in insulin receptors. The Journal of Clinical Endocrinology and Metabolism. 55: 123-31. PMID 7042734 DOI: 10.1210/Jcem-55-1-123 |
0.664 |
|
| 1982 |
Crapo PA, Scarlett JA, Kolterman OG, Sanders LR, Hofeldt FD, Olefsky JM. The Effects of Oral Fructose, Sucrose, and Glucose in Subjects with Reactive Hypoglycemia Diabetes Care. 5: 512-517. PMID 6765227 DOI: 10.2337/Diacare.5.5.512 |
0.546 |
|
| 1982 |
Gray RS, Scarlett JA, Griffin J, Olefsky JM, Kolterman OG. In vivo deactivation of peripheral, hepatic, and pancreatic insulin action in man Diabetes. 31: 929-936. PMID 6759226 DOI: 10.2337/Diab.31.10.929 |
0.591 |
|
| 1982 |
Scarlett JA, Gray RS, Griffin J, Olefsky JM, Kolterman OG. Insulin treatment reverses the insulin resistance of type II diabetes mellitus Diabetes Care. 5: 353-363. PMID 6759075 DOI: 10.2337/Diacare.5.4.353 |
0.638 |
|
| 1982 |
Ciaraldi TP, Kolterman OG, Scarlett JA, Kao M, Olefsky JM. Role of Glucose Transport in the Postreceptor Defect of Non-insulin-dependent Diabetes Mellitus Diabetes Care. 31: 1016-1022. PMID 6757010 DOI: 10.2337/Diacare.31.11.1016 |
0.653 |
|
| 1982 |
Kolterman OG, Scarlett JA, Olefsky JM. 4 Insulin resistance in non-insulindependent, type II diabetes mellitus Clinics in Endocrinology and Metabolism. 11: 363-388. PMID 6754161 DOI: 10.1016/S0300-595X(82)80020-0 |
0.471 |
|
| 1982 |
Olefsky JM, Saekow M. Mechanisms of insulin degradation by isolated rat adipocytes Molecular and Cellular Biochemistry. 47: 23-29. PMID 6752691 DOI: 10.1007/Bf00241562 |
0.574 |
|
| 1982 |
Berhanu P, Tsai P, Olefsky JM. Insulin-stimulated glucose transport in cultured fibroblasts from normal and noninsulin-dependent (type II) diabetic human subjects Journal of Clinical Endocrinology and Metabolism. 55: 1226-1230. PMID 6752171 DOI: 10.1210/Jcem-55-6-1226 |
0.578 |
|
| 1982 |
Olefsky JM. Insulin resistance in humans Gastroenterology. 83: 1313-1318. PMID 6751927 DOI: 10.1016/S0016-5085(82)80146-7 |
0.609 |
|
| 1982 |
Green A, Tager H, Rubenstein A, Frank B, Olefsky JM. Internalization and degradation of a low affinity insulin ([LeuB24]insulin) by rat adipocytes Febs Letters. 144: 255-258. PMID 6749549 DOI: 10.1016/0014-5793(82)80649-2 |
0.62 |
|
| 1982 |
Olefsky JM, Kolterman OG, Scarlett JA. Insulin action and resistance in obesity and noninsulin-dependent type II diabetes mellitus American Journal of Physiology - Endocrinology and Metabolism. 6. DOI: 10.1152/Ajpendo.1982.243.1.E15 |
0.656 |
|
| 1982 |
Kolterman OG, Griffin J, Olefsky JM. Response to glyburide is restored in confirmed secondary failure patients following 14 days of exogenous insulin therapy Clinical Research. 30. |
0.353 |
|
| 1982 |
Berhanu P, Olefsky JM, Tsai P. Insulin receptors: Internalization and molecular processing in isolated adipocytes Federation Proceedings. 41. |
0.464 |
|
| 1981 |
Prince MJ, Baldwin D, Tsai P, Olefsky JM. Regulation of insulin receptors in cultured human fibroblasts Endocrinology. 109: 1754-1759. PMID 7297502 DOI: 10.1210/Endo-109-5-1754 |
0.505 |
|
| 1981 |
Kolterman OG, Gray RS, Griffin J, Burstein P, Insel J, Scarlett JA, Olefsky JM. Receptor and postreceptor defects contribute to the insulin resistance in noninsulin-dependent diabetes mellitus Journal of Clinical Investigation. 68: 957-969. PMID 7287908 DOI: 10.1172/Jci110350 |
0.601 |
|
| 1981 |
Marshall S, Olefsky JM. Tris(hydroxmethyl)aminomethane permits the expression of insulin-induced receptor loss in isolated rat adipocytes Biochemical and Biophysical Research Communications. 102: 646-653. PMID 7030343 DOI: 10.1016/S0006-291X(81)80181-7 |
0.631 |
|
| 1981 |
Marshall S, Green A, Olefsky JM. Evidence for recycling of insulin receptors in isolated rat adipocytes Journal of Biological Chemistry. 256: 11464-11470. PMID 7028734 |
0.46 |
|
| 1981 |
Ciaraldi TP, Kolterman OG, Olefsky JM. Mechanism of the postreceptor defect in insulin action in human obesity. Decrease in glucose transport system activity. Journal of Clinical Investigation. 68: 875-880. PMID 7026616 DOI: 10.1172/Jci110342 |
0.619 |
|
| 1981 |
Olefsky JM, Green A, Ciaraldi TP, Saekow M, Rubenstein AH, Tager HS. Relationship between negative cooperativity and insulin action. Biochemistry. 20: 4488-92. PMID 7025901 DOI: 10.1021/Bi00518A038 |
0.665 |
|
| 1981 |
Baldwin D, Prince M, Tsai P, Johnson C, Lotan R, Rubenstein AH, Olefsky JM. Insulin binding, internalization, and receptor regulation in cultured human fibroblasts. The American Journal of Physiology. 241: E251-60. PMID 7025657 DOI: 10.1152/Ajpendo.1981.241.3.E251 |
0.633 |
|
| 1981 |
De Pirro R, Green A, Kao MY, Olefsky JM. Effects of prednisolone and dexamethasone in vivo and in vitro: studies of insulin binding, deoxyglucose uptake and glucose oxidation in rat adipocytes. Diabetologia. 21: 149-53. PMID 7021286 DOI: 10.1007/Bf00251283 |
0.605 |
|
| 1981 |
Marshall S, Olefsky JM. Characterization of insulin-induced receptor loss and evidence for internalization of the insulin receptor Diabetes. 30: 746-753. PMID 7021273 DOI: 10.2337/Diab.30.9.746 |
0.64 |
|
| 1981 |
Ciaraldi TP, Olefsky JM. Metabolic requirements for deactivation of insulin-stimulated glucose transport in isolated rat adipocytes Archives of Biochemistry and Biophysics. 208: 502-507. PMID 7020602 DOI: 10.1016/0003-9861(81)90537-3 |
0.559 |
|
| 1981 |
Prince MJ, Tsai P, Olefsky JM. Insulin binding, internalization, and insulin receptor regulation in fibroblasts from type II, non-insulin-dependent diabetic subjects Diabetes. 30: 596-600. PMID 7018965 DOI: 10.2337/Diab.30.7.596 |
0.639 |
|
| 1981 |
Moore P, Kolterman O, Weyant J, Olefsky JM. Insulin binding in human pregnancy: Comparisons to the postpartum, luteal, and follicular states Journal of Clinical Endocrinology and Metabolism. 52: 937-941. PMID 7014589 DOI: 10.1210/Jcem-52-5-937 |
0.557 |
|
| 1981 |
Berhanu P, Olefsky JM. Effects of insulin and insulin-like agents on the glucose transport system of cultured human fibroblasts Diabetes. 30: 523-529. PMID 7014316 DOI: 10.2337/Diab.30.6.523 |
0.645 |
|
| 1981 |
Olefsky JM. Insulin binding, biologic activity, and metabolism of biosynthetic human insulin Diabetes Care. 4: 244-247. PMID 7011736 DOI: 10.2337/Diacare.4.2.244 |
0.656 |
|
| 1981 |
Crapo PA, Reaven GM, Olefsky JM. Hormonal and substrate responses to a standard meal in normal and hypertriglyceridemic subjects Metabolism. 30: 331-334. PMID 7010076 DOI: 10.1016/0026-0495(81)90111-6 |
0.462 |
|
| 1981 |
Olefsky JM. Insulin resistance and insulin action. An in vitro and in vivo perspective Diabetes. 30: 148-162. PMID 7009267 DOI: 10.2337/Diab.30.2.148 |
0.635 |
|
| 1981 |
Olefsky JM, G. Kolterman O. Mechanisms of insulin resistance in obesity and noninsulin-dependent (type II) diabetes The American Journal of Medicine. 70: 151-168. PMID 7006388 DOI: 10.1016/0002-9343(81)90422-8 |
0.654 |
|
| 1981 |
Rosenfeld RG, Baldwin D, Dollar LA, Hintz RL, Olefsky JM, Rubenstein A. Simultaneous Inhibition of Insulin and Somatomedin-C Binding to Cultured IM-9 Lymphocytes by Naturally Occurring Antireceptor Antibodies Diabetes. 30: 979-982. PMID 6271619 DOI: 10.2337/Diab.30.11.979 |
0.573 |
|
| 1980 |
Saekow M, Olefsky JM. Effect of a high carbohydrate diet on adipocyte glucose metabolism in spontaneously obese rats and insulin-deficient diabetic rats Endocrinology. 107: 2004-2010. PMID 7428703 DOI: 10.1210/Endo-107-6-2004 |
0.528 |
|
| 1980 |
Greenfield M, Kolterman O, Olefsky J, Reaven GM. Mechanism of hypertriglyceridaemia in diabetic patients with fasting hyperglycaemia Diabetologia. 18: 441-446. PMID 7418956 DOI: 10.1007/Bf00261698 |
0.537 |
|
| 1980 |
Olefsky JM, Crapo P. Fructose, xylitol, and sorbitol Diabetes Care. 3: 390-393. PMID 7389552 DOI: 10.2337/Diacare.3.2.390 |
0.478 |
|
| 1980 |
Ciaraldi TP, Olefsky JM. Relationship between deactivation of insulin-stimulated glucose transport and insulin dissociation in isolated rat adipocytes Journal of Biological Chemistry. 255: 327-330. PMID 7356614 |
0.57 |
|
| 1980 |
Given BD, Mako ME, Tager HS, Baldwin D, Markese J, Rubenstein AH, Olefsky J, Kobayashi M, Kolterman O, Poucher R. Diabetes due to secretion of an abnormal insulin. The New England Journal of Medicine. 302: 129-35. PMID 7350438 DOI: 10.1056/Nejm198001173020301 |
0.633 |
|
| 1980 |
Crapo PA, Kolterman OG, Olefsky JM. Effects of Oral Fructose in Normal, Diabetic, and Impaired Glucose Tolerance Subjects Diabetes Care. 3: 575-581. PMID 7002511 DOI: 10.2337/Diacare.3.5.575 |
0.562 |
|
| 1980 |
Marshall S, Olefsky JM. The endocytotic-internalization pathway of insulin metabolism: Relationship to insulin degradation and activation of glucose transport Endocrinology. 107: 1937-1945. PMID 7000505 DOI: 10.1210/Endo-107-6-1937 |
0.667 |
|
| 1980 |
Marshall S, Olefsky JM. Effects of insulin incubation on insulin binding, glucose transport, and insulin degradation by isolated rat adipocytes. Evidence for hormone-induced desensitization at the receptor and postreceptor level Journal of Clinical Investigation. 66: 763-772. PMID 6999035 DOI: 10.1172/Jci109914 |
0.669 |
|
| 1980 |
Tager H, Thomas N, Assoian R, Rubenstein A, Saekow M, Olefsky J, Kaiser ET. Semisynthesis and biological activity of porcine [LeuB24]insulin and [LeuB25]insulin. Proceedings of the National Academy of Sciences of the United States of America. 77: 3181-5. PMID 6997872 DOI: 10.1073/Pnas.77.6.3181 |
0.615 |
|
| 1980 |
Kolterman OG, Insel J, Saekow M, Olefsky JM. Mechanisms of insulin resistance in human obesity. Evidence for receptor and postreceptor defects Journal of Clinical Investigation. 65: 1272-1284. PMID 6997333 DOI: 10.1172/Jci109790 |
0.646 |
|
| 1980 |
Crapo PA, Kolterman OG, Waldeck N, Reaven GM, Olefsky JM. Postprandial hormonal responses to different types of complex carbohydrate in individuals with impaired glucose tolerance. The American Journal of Clinical Nutrition. 33: 1723-1728. PMID 6996472 DOI: 10.1093/Ajcn/33.8.1723 |
0.522 |
|
| 1980 |
Olefsky JM, Saekow M, Tager H, Rubenstein AH. Characterization of a mutant human insulin species Journal of Biological Chemistry. 255: 6098-6105. PMID 6993466 |
0.421 |
|
| 1980 |
Siegel J, Olefsky JM. Role of intracellular energy in insulin's ability to activate 3-O-methylglucose transport by rat adipocytes Biochemistry. 19: 2183-2190. PMID 6990973 DOI: 10.1021/Bi00551A029 |
0.593 |
|
| 1980 |
Insel JR, Kolterman OG, Saekow M, Olefsky JM. Short-term regulation of insulin receptor affinity in man Diabetes. 29: 132-139. PMID 6986298 DOI: 10.2337/Diab.29.2.132 |
0.641 |
|
| 1980 |
Prince MJ, Olefsky JM. Direct in vitro effect of a sulfonylurea to increase human fibrolast insulin receptors Journal of Clinical Investigation. 66: 608-611. PMID 6772676 DOI: 10.1172/Jci109894 |
0.594 |
|
| 1980 |
Baldwin D, Prince M, Marshall S, Davies P, Olefsky JM. Regulation of insulin receptors: evidence for involvement of an endocytotic internalization pathway. Proceedings of the National Academy of Sciences of the United States of America. 77: 5975-5978. PMID 6108561 DOI: 10.1073/Pnas.77.10.5975 |
0.601 |
|
| 1980 |
Kolterman OG, Olefsky JM, Kurahara C, Taylor K. A defect in cell-mediated immune function in insulin-resistant diabetic and obese subjects. Journal of Laboratory and Clinical Medicine. 96: 535-543. DOI: 10.5555/Uri:Pii:0022214380901584 |
0.53 |
|
| 1979 |
Davis BM, Bernstein R, Kolterman O, Olefsky JM, Reaven GM. Defect in glucose removal in nonketotic diabetic patients with fasting hyperglycemia. Diabetes. 28: 32-4. PMID 569610 DOI: 10.2337/Diab.28.1.32 |
0.568 |
|
| 1979 |
Marshall S, Olefsky JM. Effects of lysosomotropic agents on insulin interactions with adipocytes. Evidence for a lysosomal pathway for insulin processing and degradation Journal of Biological Chemistry. 254: 10153-10160. PMID 489589 |
0.573 |
|
| 1979 |
Kobayashi M, Olefsky JM. Effect of experimental hyperinsulinaemia on intracellular glucose metabolism of isolated adipocytes Diabetologia. 17: 111-116. PMID 488566 DOI: 10.1007/Bf01222211 |
0.53 |
|
| 1979 |
Ciaraldi TP, Olefsky JM. Coupling of insulin receptors to glucose transport: A temperature-dependent time lag in activation of glucose transport Archives of Biochemistry and Biophysics. 193: 221-231. PMID 453850 DOI: 10.1016/0003-9861(79)90026-2 |
0.612 |
|
| 1979 |
Olefsky JM. Comparison of the effects of insulin and insulin-like agents on different aspects of adipocyte metabolism Hormone and Metabolic Research. 11: 209-213. PMID 447201 DOI: 10.1055/S-0028-1092709 |
0.64 |
|
| 1979 |
Kolterman OG, Greenfield M, Reaven GM, Saekow M, Olefsky JM. Effect of a High Carbohydrate Diet on Insulin Binding to Adipocytes and on Insulin Action in vivo in Man Diabetes. 28: 731-745. PMID 446930 DOI: 10.2337/Diab.28.8.731 |
0.623 |
|
| 1979 |
Olefsky JM, Chang H. Further evidence for functional heterogeneity of adipocyte insulin receptors Endocrinology. 104: 462-466. PMID 446370 DOI: 10.1210/Endo-104-2-462 |
0.636 |
|
| 1979 |
Ciaraldi TP, Kolterman OG, Siegel JA, Olefsky JM. Insulin-stimulated glucose transport in human adipocytes. American Journal of Physiology-Endocrinology and Metabolism. 236. PMID 443417 DOI: 10.1152/Ajpendo.1979.236.6.E621 |
0.587 |
|
| 1979 |
Olefsky JM, Kobayashi M, Chang H. Interactions between insulin and its receptors after the initial binding event. Functional heterogeneity and relationships to insulin degradation Diabetes. 28: 460-471. PMID 437375 DOI: 10.2337/Diab.28.5.460 |
0.626 |
|
| 1979 |
Kolterman OG, Saekow M, Olefsky JM. The effects of acute and chronic starvation on insulin binding to isolated human adipocytes Journal of Clinical Endocrinology and Metabolism. 48: 836-842. PMID 429529 DOI: 10.1210/Jcem-48-5-836 |
0.546 |
|
| 1979 |
Kolterman OG, Reaven GM, Olefsky JM. Relationship between in vivo insulin resistance and decreased insulin receptors in obese man Journal of Clinical Endocrinology and Metabolism. 48: 487-494. PMID 429500 DOI: 10.1210/Jcem-48-3-487 |
0.654 |
|
| 1979 |
Tager H, Given B, Baldwin D, Mako M, Markese J, Rubenstein A, Olefsky J, Kobayashi M, Kolterman O, Poucher R. A structurally abnormal insulin causing human diabetes Nature. 281: 122-125. PMID 381941 DOI: 10.1038/281122A0 |
0.642 |
|
| 1979 |
Kobayashi M, Olefsky JM. Effects of streptozotocin-induced diabetes on insulin binding, glucose transport, and intracellular glucose metabolism in isolated rat adipocytes Diabetes. 28: 87-95. PMID 154427 DOI: 10.2337/Diab.28.2.87 |
0.588 |
|
| 1979 |
Siegel J, Olefsky JM. Role of intracellular energy in insulin's ability to activate adipocyte glucose transport Clinical Research. 27. |
0.484 |
|
| 1979 |
Kolterman OG, Insel JR, Saekow M, Olefsky JM. Shortterm regulation of insulin receptors in man Clinical Research. 27. |
0.521 |
|
| 1979 |
Ciaraldi T, Kolterman OG, Siegel JA, Olefsky JM. Insulin stimulated glucose transport in human adipocytes Clinical Research. 27. |
0.507 |
|
| 1978 |
Olefsky JM, Saekow M. The effects of dietary carbohydrate content on insulin binding and glucose metabolism by isolated rat adipocytes Endocrinology. 103: 2252-2263. PMID 748046 DOI: 10.1210/Endo-103-6-2252 |
0.643 |
|
| 1978 |
Olefsky JM, Kobayashi M. Ability of circulating insulin to chronically regulate the cellular glucose transport system Metabolism. 27: 1917-1929. PMID 723641 DOI: 10.1016/S0026-0495(78)80009-2 |
0.561 |
|
| 1978 |
Greenfield M, Kolterman O, Olefsky JM, Reaven GM. The effect of ten days of fasting on various aspects of carbohydrate metabolism in obese diabetic subjects with significant fasting hyperglycemia Metabolism: Clinical and Experimental. 27: 1839-1852. PMID 723636 DOI: 10.1016/S0026-0495(78)80003-1 |
0.523 |
|
| 1978 |
Olefsky JM, Chang H. Insulin binding to adipocytes. Evidence for functionally distinct receptors Diabetes. 27: 946-958. PMID 689306 DOI: 10.2337/Diab.27.9.946 |
0.644 |
|
| 1978 |
Kobayashi M, Olefsky JM. Long-term regulation of adipocyte glucose transport capacity by circulating insulin in rats Journal of Clinical Investigation. 62: 73-81. PMID 659640 DOI: 10.1172/Jci109116 |
0.566 |
|
| 1978 |
Olefsky JM. Mechanisms of the ability of insulin to activate the glucose transport system in rat adipocytes Biochemical Journal. 172: 137-145. PMID 656068 DOI: 10.1042/Bj1720137 |
0.608 |
|
| 1978 |
Olefsky JM, Kobayashi M. Mechanisms of the fasting-induced increase in insulin binding to rat adipocytes Journal of Clinical Investigation. 61: 329-338. PMID 621276 DOI: 10.1172/Jci108943 |
0.602 |
|
| 1978 |
Reaven GM, Olefsky JM. The role of insulin resistance in the pathogenesis of diabetes mellitus Advances in Metabolic Disorders. 9: 313-331. PMID 417568 DOI: 10.1016/B978-0-12-027309-6.50021-5 |
0.643 |
|
| 1978 |
Kobayashi M, Olefsky JM, Elders J, Mako ME, Given BD, Schedwie HK, Fiser RH, Hintz RL, Horner JA, Rubenstein AH. Insulin resistance due to a defect distal to the insulin receptor: demonstration in a patient with leprechaunism Proceedings of the National Academy of Sciences of the United States of America. 75: 3469-3473. PMID 277948 DOI: 10.1073/Pnas.75.7.3469 |
0.661 |
|
| 1978 |
Bernstein RM, Davis BM, Olefsky JM, Reaven GM. Hepatic insulin responsiveness in patients with endogenous hypertriglyceridaemia. Diabetologia. 14: 249-53. PMID 205476 DOI: 10.1007/Bf01219424 |
0.64 |
|
| 1978 |
Kobayashi M, Olefsky JM. Effect of experimental hyperinsulinemia on insulin binding and glucose transport in isolated rat adipocytes American Journal of Physiology Endocrinology Metabolism and Gastrointestinal Physiology. 4. DOI: 10.1152/Ajpendo.1978.235.1.E53 |
0.666 |
|
| 1978 |
Kobayashi M, Chang H, Olefsky JM. Evidence for functionally distinct high and low affinity adipocyte insulin receptors Clinical Research. 26. |
0.482 |
|
| 1978 |
Kolterman OG, Reavey GM, Olefsky JM. Effect of a high carbohydrate diet on in vitro insulin binding and in vivo insulin sensitivity in man Clinical Research. 26. |
0.537 |
|
| 1977 |
Olefsky JM, Sperling MA, Reaven GM. Does glucagon play a role in the insulin resistance of patients with adult non-ketotic diabetes? Diabetologia. 13: 327-330. PMID 913924 DOI: 10.1007/Bf01223274 |
0.519 |
|
| 1977 |
Olefsky JM. Insensitivity of large rat adipocytes to the antilipolytic effects of insulin Journal of Lipid Research. 18: 459-464. PMID 894138 |
0.574 |
|
| 1977 |
Reaven GM, Olefsky JM. Relationship between heterogeneity of insulin responses and insulin resistance in normal subjects and patients with chemical diabetes Diabetologia. 13: 201-206. PMID 873087 DOI: 10.1007/Bf01219700 |
0.631 |
|
| 1977 |
Olefsky JM, Reaven GM. Insulin binding in diabetes. Relationships with plasma insulin levels and insulin sensitivity Diabetes. 26: 680-688. PMID 873075 DOI: 10.2337/Diab.26.7.680 |
0.638 |
|
| 1977 |
Olefsky JM. Interaction between insulin receptors and glucose transport: Effect of prostaglandin E2 Biochemical and Biophysical Research Communications. 75: 271-276. PMID 851438 DOI: 10.1016/0006-291X(77)91039-7 |
0.601 |
|
| 1977 |
Olefsky JM. Mechanisms of decreased insulin responsiveness of large adipocytes Endocrinology. 100: 1169-1177. PMID 837879 DOI: 10.1210/Endo-100-4-1169 |
0.538 |
|
| 1977 |
Crapo PA, Reaven G, Olefsky J. Postprandial Plasma-glucose and -insulin Responses to Different Complex Carbohydrates Diabetes. 26: 1178-1183. PMID 590639 DOI: 10.2337/Diab.26.12.1178 |
0.539 |
|
| 1977 |
Scarlett JA, Mako ME, Rubenstein AH, Blix PM, Goldman J, Horwitz DL, Tager H, Jaspan JB, Stjernholm MR, Olefsky JM. Factitious hypoglycemia. Diagnosis by measurement of serum C-peptide immunoreactivity and insulin-binding antibodies New England Journal of Medicine. 297: 1029-1032. PMID 198659 DOI: 10.1056/Nejm197711102971903 |
0.595 |
|
| 1977 |
Reaven GM, Bernstein R, Olefsky JM. Variations in tissue response to insulin in patients with primary hypertriglyceridemia Clinical Research. 25. |
0.42 |
|
| 1977 |
Kolterman O, Reaven GM, Olefsky JM. Insulin binding in chemical diabetes: relationship to plasma insulin levels and insulin sensitivity Clinical Research. 25. |
0.544 |
|
| 1977 |
Reaven GM, Bernstein RM, Davis BM, Olefsky JM. Hepatic insulin responsiveness in patients with endogenous hypertriglyceridaemia Diabetologia. 13. |
0.449 |
|
| 1977 |
Kolterman OG, Reaven GM, Olefsky JM. Insulin resistance in obesity: an insulin receptor defect Clinical Research. 25. |
0.529 |
|
| 1976 |
Ginsberg H, Olefsky JM, Kimmerling G, Crapo P, Reaven GM. Induction of hypertriglyceridemia by a low-fat diet. The Journal of Clinical Endocrinology and Metabolism. 42: 729-735. PMID 1262445 DOI: 10.1210/Jcem-42-4-729 |
0.389 |
|
| 1976 |
Olefsky JM. Effects of fasting on insulin binding, glucose transport, and glucose oxidation in isolated rat adipocytes. Relationships between insulin receptors and insulin action Journal of Clinical Investigation. 58: 1450-1460. PMID 993354 DOI: 10.1172/Jci108601 |
0.618 |
|
| 1976 |
Olefsky JM. Insulin's effect on glucose oxidation independent of glucose transport Biochemical and Biophysical Research Communications. 71: 106-113. PMID 962906 DOI: 10.1016/0006-291X(76)90255-2 |
0.595 |
|
| 1976 |
Kimmerling G, Javorski WC, Olefsky JM, Reaven GM. Locating the site(s) of insulin resistance in patients with nonketotic diabetes mellitus Diabetes. 25: 673-678. PMID 955298 DOI: 10.2337/Diab.25.8.673 |
0.625 |
|
| 1976 |
Olefsky JM, Reaven GM. Insulin binding to monocytes and total mononuclear leukocytes from normal and diabetic patients Journal of Clinical Endocrinology and Metabolism. 43: 226-228. PMID 947940 DOI: 10.1210/Jcem-43-1-226 |
0.464 |
|
| 1976 |
Reaven GM, Bernstein R, Davis B, Olefsky JM. Nonketotic diabetes mellitus: Insulin deficiency or insulin resistance? The American Journal of Medicine. 60: 80-88. PMID 814810 DOI: 10.1016/0002-9343(76)90536-2 |
0.646 |
|
| 1976 |
Olefsky JM. The insulin receptor: its role in insulin resistance of obesity and diabetes Diabetes. 25: 1154-1162. PMID 791735 DOI: 10.2337/Diab.25.12.1154 |
0.649 |
|
| 1976 |
Olefsky JM. The effects of spontaneous obesity on insulin binding, glucose transport, and glucose oxidation of isolated rat adipocytes Journal of Clinical Investigation. 57: 842-851. PMID 181402 DOI: 10.1172/Jci108360 |
0.639 |
|
| 1976 |
Olefsky JM, Kimmerling G. Effects of glucocorticoids on carbohydrate metabolism American Journal of the Medical Sciences. 271: 202-210. PMID 178180 DOI: 10.1097/00000441-197603000-00009 |
0.488 |
|
| 1976 |
Olefsky JM. Decreased insulin binding to adipocytes and circulating monocytes from obese subjects Journal of Clinical Investigation. 57: 1165-1172. PMID 177453 DOI: 10.1172/Jci108384 |
0.593 |
|
| 1976 |
Olefsky JM, Reaven GM. Effects of sulfonylurea therapy on insulin binding to mononuclear leukocytes of diabetic patients The American Journal of Medicine. 60: 89-95. PMID 175653 DOI: 10.1016/0002-9343(76)90537-4 |
0.578 |
|
| 1976 |
Olefsky J, Bacon VC, Baur S. Insulin receptors of skeletal muscle: specific insulin binding sites and demonstration of decreased numbers of sites in obese rats. Metabolism-Clinical and Experimental. 25: 179-191. PMID 2834 DOI: 10.1016/0026-0495(76)90048-2 |
0.547 |
|
| 1976 |
Crapo PA, Reaven G, Olefsky J. Plasma Glucose and Insulin Responses to Orally Administered Simple and Complex Carbohydrates Diabetes. 25: 741-747. DOI: 10.2337/Diab.25.9.741 |
0.568 |
|
| 1976 |
Olefsky JM, Reaven GM. The effects of fasting on insulin binding, glucose transport and glucose oxidation in rat adipocytes Diabetologia. 12. |
0.477 |
|
| 1975 |
Olefsky JM. Effect of dexamethasone on insulin binding, glucose transport, and glucose oxidation of isolated rat adipocytes Journal of Clinical Investigation. 56: 1499-1508. PMID 1202081 DOI: 10.1172/Jci108231 |
0.615 |
|
| 1975 |
Ginsberg H, Olefsky JM, Reaven GM. Evaluation of Insulin Resistance in Patients with Primary Hyperparathyroidism Proceedings of the Society For Experimental Biology and Medicine. 148: 942-945. PMID 1129318 DOI: 10.3181/00379727-148-38665 |
0.611 |
|
| 1975 |
Mondon CE, Dolkas CB, Olefsky JM, Reaven GM. Insulin Sensitivity of Isolated Perfused Rat Liver Diabetes. 24: 225-229. PMID 1123110 DOI: 10.2337/Diab.24.2.225 |
0.616 |
|
| 1975 |
Olefsky JM, Johnson J, Liu F, Jen P, Reaven GM. The effects of acute and chronic dexamethasone administration on insulin binding to isolated rat hepatocytes and adipocytes. Metabolism: Clinical and Experimental. 24: 517-27. PMID 1117842 DOI: 10.1016/0026-0495(75)90076-1 |
0.541 |
|
| 1975 |
Olefsky J, Crapo PA, Ginsberg H, Reaven GM. Metabolic effects of increased caloric intake in man. Metabolism-Clinical and Experimental. 24: 495-503. PMID 1117841 DOI: 10.1016/0026-0495(75)90074-8 |
0.601 |
|
| 1975 |
Ginsberg H, Kimmerling G, Olefsky JM, Reaven GM. Demonstration of insulin resistance in untreated adult onset diabetic subjects with fasting hyperglycemia Journal of Clinical Investigation. 55: 454-461. PMID 1117064 DOI: 10.1172/Jci107951 |
0.591 |
|
| 1975 |
Mondon CE, Olefsky JM, Dolkas CB, Reaven GM. Removal of insulin by perfused rat liver: effect of concentration. Metabolism-Clinical and Experimental. 24: 153-160. PMID 1113679 DOI: 10.1016/0026-0495(75)90016-5 |
0.587 |
|
| 1975 |
Olefsky JM, Johnson J, Liu F. Comparison of 125I insulin binding and degradation to isolated rat hepatocytes and liver membranes Diabetes. 24: 801-810. PMID 169175 DOI: 10.2337/Diab.24.9.801 |
0.582 |
|
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