Sudha K. Shenoy - Publications

Affiliations: 
Department of Medicine Duke Medical School, Durham, NC, United States 

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Ahn S, Shenoy SK, Luttrell LM, Lefkowitz RJ. SnapShot: β-Arrestin Functions. Cell. 182: 1362-1362.e1. PMID 32888497 DOI: 10.1016/j.cell.2020.07.034  1
2019 Toth K, Nagi K, Slosky LM, Rochelle L, Ray C, Kaur S, Shenoy SK, Caron MG, Barak LS. Encoding the β-Arrestin Trafficking Fate of Ghrelin Receptor GHSR1a: C-Tail-Independent Molecular Determinants in GPCRs. Acs Pharmacology & Translational Science. 2: 230-246. PMID 32259059 DOI: 10.1021/acsptsci.9b00018  0.68
2018 Yu SM, Jean-Charles PY, Abraham DM, Kaur S, Gareri C, Mao L, Rockman HA, Shenoy SK. The deubiquitinase ubiquitin specific protease 20 is a positive modulator of myocardial β1-adrenergic receptor expression and signaling. The Journal of Biological Chemistry. PMID 30538132 DOI: 10.1074/jbc.RA118.004926  0.36
2018 Jean-Charles PY, Wu JH, Zhang L, Kaur S, Nepliouev I, Stiber JA, Brian L, Qi R, Wertman V, Shenoy SK, Freedman NJ. USP20 (Ubiquitin-Specific Protease 20) Inhibits TNF (Tumor Necrosis Factor)-Triggered Smooth Muscle Cell Inflammation and Attenuates Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 38: 2295-2305. PMID 30354204 DOI: 10.1161/ATVBAHA.118.311071  0.48
2018 Luttrell LM, Wang J, Plouffe B, Smith JS, Yamani L, Kaur S, Jean-Charles PY, Gauthier C, Lee MH, Pani B, Kim J, Ahn S, Rajagopal S, Reiter E, Bouvier M, ... Shenoy SK, et al. Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9. Science Signaling. 11. PMID 30254056 DOI: 10.1126/scisignal.aat7650  1
2018 Zhang L, Wu JH, Huang TQ, Nepliouev I, Brian L, Zhang Z, Wertman V, Rudemiller NP, McMahon TJ, Shenoy SK, Miller FJ, Crowley SD, Freedman NJ, Stiber JA. Drebrin Regulates Angiotensin II-Induced Aortic Remodeling. Cardiovascular Research. PMID 29931051 DOI: 10.1093/cvr/cvy151  0.48
2017 Zhang L, Wu JH, Otto JC, Gurley SB, Hauser ER, Shenoy SK, Nagi K, Brian L, Wertman V, Mattocks N, Lawson JH, Freedman NJ. Interleukin-9 mediates chronic kidney disease-dependent vein graft disease: a role for mast cells. Cardiovascular Research. PMID 29048463 DOI: 10.1093/cvr/cvx177  0.48
2017 Jean-Charles PY, Yu SM, Abraham D, Kommaddi RP, Mao L, Strachan RT, Zhang ZS, Bowles DE, Brian L, Stiber JA, Jones SN, Koch WJ, Rockman HA, Shenoy SK. Mdm2 regulates cardiac contractility by inhibiting GRK2-mediated desensitization of β-adrenergic receptor signaling. Jci Insight. 2. PMID 28878120 DOI: 10.1172/jci.insight.95998  0.36
2017 Jean-Charles PY, Kaur S, Shenoy SK. GPCR signaling via β-arrestin-dependent mechanisms. Journal of Cardiovascular Pharmacology. PMID 28328745 DOI: 10.1097/FJC.0000000000000482  0.36
2017 Freedman NJ, Shenoy SK. Regulation of inflammation by β-arrestins: Not just receptor Tales. Cellular Signalling. PMID 28189586 DOI: 10.1016/j.cellsig.2017.02.008  0.48
2016 Jean-Charles PY, Freedman NJ, Shenoy SK. Chapter Nine - Cellular Roles of Beta-Arrestins as Substrates and Adaptors of Ubiquitination and Deubiquitination. Progress in Molecular Biology and Translational Science. 141: 339-69. PMID 27378762 DOI: 10.1016/bs.pmbts.2016.04.003  1
2016 Jean-Charles PY, Rajiv V, Shenoy SK. Cover Image, Volume 231, Number 10, October 2016. Journal of Cellular Physiology. 231: i. PMID 27315163 DOI: 10.1002/jcp.25462  1
2016 Jean-Charles PY, Zhang L, Wu JH, Han SO, Brian L, Freedman NJ, Shenoy SK. Ubiquitin-specific protease 20 Regulates the Reciprocal Functions of Beta-arrestin2 in Toll-like Receptor 4-promoted NFkappaB Activation. The Journal of Biological Chemistry. PMID 26839314 DOI: 10.1074/jbc.M115.687129  1
2016 Jean-Charles PY, Rajiv V, Shenoy SK. Ubiquitin-Related Roles of β-Arrestins in Endocytic Trafficking and Signal Transduction Journal of Cellular Physiology. DOI: 10.1002/jcp.25317  1
2015 Kommaddi RP, Jean-Charles PY, Shenoy SK. Phosphorylation of the deubiquitinase USP20 by protein kinase A regulates post-endocytic trafficking of β2 adrenergic receptors to autophagosomes during physiological stress. The Journal of Biological Chemistry. 290: 8888-903. PMID 25666616 DOI: 10.1074/jbc.M114.630541  1
2014 Shenoy SK. Deubiquitinases and their emerging roles in β-arrestin-mediated signaling. Methods in Enzymology. 535: 351-70. PMID 24377933 DOI: 10.1016/B978-0-12-397925-4.00020-1  1
2014 Shenoy SK. Arrestin interaction with E3 ubiquitin ligases and deubiquitinases: functional and therapeutic implications. Handbook of Experimental Pharmacology. 219: 187-203. PMID 24292831 DOI: 10.1007/978-3-642-41199-1_10  1
2013 Kommaddi RP, Shenoy SK. Arrestins and protein ubiquitination. Progress in Molecular Biology and Translational Science. 118: 175-204. PMID 23764054 DOI: 10.1016/B978-0-12-394440-5.00007-3  1
2013 Han SO, Kommaddi RP, Shenoy SK. Distinct roles for β-arrestin2 and arrestin-domain-containing proteins in β2 adrenergic receptor trafficking. Embo Reports. 14: 164-71. PMID 23208550 DOI: 10.1038/embor.2012.187  1
2013 Shenoy S. Regulation of β2Adrenergic Receptor Trafficking and Signaling by Ubiquitination and Deubiquitination Catecholamine Research in the 21st Century: Abstracts and Graphical Abstracts, 10th International Catecholamine Symposium, 2012. 95-96. DOI: 10.1016/B978-0-12-800044-1.00082-9  1
2012 Han SO, Xiao K, Kim J, Wu JH, Wisler JW, Nakamura N, Freedman NJ, Shenoy SK. MARCH2 promotes endocytosis and lysosomal sorting of carvedilol-bound β(2)-adrenergic receptors. The Journal of Cell Biology. 199: 817-30. PMID 23166351 DOI: 10.1083/jcb.201208192  1
2012 Wu JH, Zhang L, Fanaroff AC, Cai X, Sharma KC, Brian L, Exum ST, Shenoy SK, Peppel K, Freedman NJ. G protein-coupled receptor kinase-5 attenuates atherosclerosis by regulating receptor tyrosine kinases and 7-transmembrane receptors. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 308-16. PMID 22095977 DOI: 10.1161/ATVBAHA.111.239608  0.48
2012 Shenoy SK, Han S, Zhao YL, Hara MR, Oliver T, Cao Y, Dewhirst MW. β-arrestin1 mediates metastatic growth of breast cancer cells by facilitating HIF-1-dependent VEGF expression. Oncogene. 31: 282-92. PMID 21685944 DOI: 10.1038/onc.2011.238  1
2011 Sarker S, Xiao K, Shenoy SK. A tale of two sites: How ubiquitination of a G protein-coupled receptor is coupled to its lysosomal trafficking from distinct receptor domains. Communicative & Integrative Biology. 4: 528-31. PMID 22046454 DOI: 10.4161/cib.4.5.16458  1
2011 Shenoy SK, Rockman HA. Cardiovascular biology: heart fails without pump partner. Nature. 477: 546-7. PMID 21956327 DOI: 10.1038/477546a  1
2011 Nobles KN, Xiao K, Ahn S, Shukla AK, Lam CM, Rajagopal S, Strachan RT, Huang TY, Bressler EA, Hara MR, Shenoy SK, Gygi SP, Lefkowitz RJ. Distinct phosphorylation sites on the β(2)-adrenergic receptor establish a barcode that encodes differential functions of β-arrestin. Science Signaling. 4: ra51. PMID 21868357 DOI: 10.1126/scisignal.2001707  1
2011 Hara MR, Kovacs JJ, Whalen EJ, Rajagopal S, Strachan RT, Grant W, Towers AJ, Williams B, Lam CM, Xiao K, Shenoy SK, Gregory SG, Ahn S, Duckett DR, Lefkowitz RJ. A stress response pathway regulates DNA damage through β2-adrenoreceptors and β-arrestin-1. Nature. 477: 349-53. PMID 21857681 DOI: 10.1038/nature10368  1
2011 Shenoy SK, Lefkowitz RJ. β-Arrestin-mediated receptor trafficking and signal transduction. Trends in Pharmacological Sciences. 32: 521-33. PMID 21680031 DOI: 10.1016/j.tips.2011.05.002  1
2011 Xiao K, Shenoy SK. β2-adrenergic receptor lysosomal trafficking is regulated by ubiquitination of lysyl residues in two distinct receptor domains Journal of Biological Chemistry. 286: 12785-12795. PMID 21330366 DOI: 10.1074/jbc.M110.203091  1
2011 Sarker S, Xiao K, Shenoy SK. A tale of two sites: How ubiquitination of a G protein-coupled receptor is coupled to its lysosomal trafficking from distinct receptor domains Communicative and Integrative Biology. 4: 528-531. DOI: 10.4161/cib.4.5.16458  1
2010 Shukla AK, Kim J, Ahn S, Xiao K, Shenoy SK, Liedtke W, Lefkowitz RJ. Arresting a transient receptor potential (TRP) channel: beta-arrestin 1 mediates ubiquitination and functional down-regulation of TRPV4. The Journal of Biological Chemistry. 285: 30115-25. PMID 20650893 DOI: 10.1074/jbc.M110.141549  1
2009 Berthouze M, Venkataramanan V, Li Y, Shenoy SK. The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization. The Embo Journal. 28: 1684-96. PMID 19424180 DOI: 10.1038/emboj.2009.128  0.68
2009 Shenoy SK, Modi AS, Shukla AK, Xiao K, Berthouze M, Ahn S, Wilkinson KD, Miller WE, Lefkowitz RJ. Beta-arrestin-dependent signaling and trafficking of 7-transmembrane receptors is reciprocally regulated by the deubiquitinase USP33 and the E3 ligase Mdm2. Proceedings of the National Academy of Sciences of the United States of America. 106: 6650-5. PMID 19363159 DOI: 10.1073/pnas.0901083106  1
2009 Cai X, Wu JH, Exum ST, Oppermann M, Premont RT, Shenoy SK, Freedman NJ. Reciprocal regulation of the platelet-derived growth factor receptor-beta and G protein-coupled receptor kinase 5 by cross-phosphorylation: effects on catalysis. Molecular Pharmacology. 75: 626-36. PMID 19092051 DOI: 10.1124/mol.108.050278  0.48
2008 Shukla AK, Violin JD, Whalen EJ, Gesty-Palmer D, Shenoy SK, Lefkowitz RJ. Distinct conformational changes in beta-arrestin report biased agonism at seven-transmembrane receptors. Proceedings of the National Academy of Sciences of the United States of America. 105: 9988-93. PMID 18621717 DOI: 10.1073/pnas.0804246105  1
2008 Shenoy SK, Xiao K, Venkataramanan V, Snyder PM, Freedman NJ, Weissman AM. Nedd4 mediates agonist-dependent ubiquitination, lysosomal targeting, and degradation of the beta2-adrenergic receptor. The Journal of Biological Chemistry. 283: 22166-76. PMID 18544533 DOI: 10.1074/jbc.M709668200  1
2008 Drake MT, Violin JD, Whalen EJ, Wisler JW, Shenoy SK, Lefkowitz RJ. beta-arrestin-biased agonism at the beta2-adrenergic receptor. The Journal of Biological Chemistry. 283: 5669-76. PMID 18086673 DOI: 10.1074/jbc.M708118200  1
2007 Wisler JW, DeWire SM, Whalen EJ, Violin JD, Drake MT, Ahn S, Shenoy SK, Lefkowitz RJ. A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling. Proceedings of the National Academy of Sciences of the United States of America. 104: 16657-62. PMID 17925438 DOI: 10.1073/pnas.0707936104  1
2007 Shenoy SK, Barak LS, Xiao K, Ahn S, Berthouze M, Shukla AK, Luttrell LM, Lefkowitz RJ. Ubiquitination of beta-arrestin links seven-transmembrane receptor endocytosis and ERK activation. The Journal of Biological Chemistry. 282: 29549-62. PMID 17666399 DOI: 10.1074/jbc.M700852200  1
2007 Xiao K, McClatchy DB, Shukla AK, Zhao Y, Chen M, Shenoy SK, Yates JR, Lefkowitz RJ. Functional specialization of beta-arrestin interactions revealed by proteomic analysis. Proceedings of the National Academy of Sciences of the United States of America. 104: 12011-6. PMID 17620599 DOI: 10.1073/pnas.0704849104  1
2007 DeWire SM, Ahn S, Lefkowitz RJ, Shenoy SK. Beta-arrestins and cell signaling. Annual Review of Physiology. 69: 483-510. PMID 17305471 DOI: 10.1146/annurev.physiol.69.022405.154749  1
2007 Girnita L, Shenoy SK, Sehat B, Vasilcanu R, Vasilcanu D, Girnita A, Lefkowitz RJ, Larsson O. Beta-arrestin and Mdm2 mediate IGF-1 receptor-stimulated ERK activation and cell cycle progression. The Journal of Biological Chemistry. 282: 11329-38. PMID 17303558 DOI: 10.1074/jbc.M611526200  1
2006 Drake MT, Shenoy SK, Lefkowitz RJ. Trafficking of G protein-coupled receptors. Circulation Research. 99: 570-82. PMID 16973913 DOI: 10.1161/01.RES.0000242563.47507.ce  1
2006 Shenoy SK, Drake MT, Nelson CD, Houtz DA, Xiao K, Madabushi S, Reiter E, Premont RT, Lichtarge O, Lefkowitz RJ. beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor. The Journal of Biological Chemistry. 281: 1261-73. PMID 16280323 DOI: 10.1074/jbc.M506576200  1
2005 Shenoy SK, Lefkowitz RJ. Receptor regulation: beta-arrestin moves up a notch. Nature Cell Biology. 7: 1159-61. PMID 16319967 DOI: 10.1038/ncb1205-1059  1
2005 Shenoy SK, Lefkowitz RJ. Angiotensin II-stimulated signaling through G proteins and beta-arrestin. Science's Stke : Signal Transduction Knowledge Environment. 2005: cm14. PMID 16304060 DOI: 10.1126/stke.3112005cm14  1
2005 Shenoy SK, Lefkowitz RJ. Seven-transmembrane receptor signaling through beta-arrestin. Science's Stke : Signal Transduction Knowledge Environment. 2005: cm10. PMID 16267056 DOI: 10.1126/stke.2005/308/cm10  1
2005 Girnita L, Shenoy SK, Sehat B, Vasilcanu R, Girnita A, Lefkowitz RJ, Larsson O. {beta}-Arrestin is crucial for ubiquitination and down-regulation of the insulin-like growth factor-1 receptor by acting as adaptor for the MDM2 E3 ligase. The Journal of Biological Chemistry. 280: 24412-9. PMID 15878855 DOI: 10.1074/jbc.M501129200  1
2005 Lefkowitz RJ, Shenoy SK. Transduction of receptor signals by beta-arrestins. Science (New York, N.Y.). 308: 512-7. PMID 15845844 DOI: 10.1126/science.1109237  1
2005 Shenoy SK, Lefkowitz RJ. Receptor-specific ubiquitination of beta-arrestin directs assembly and targeting of seven-transmembrane receptor signalosomes. The Journal of Biological Chemistry. 280: 15315-24. PMID 15699045 DOI: 10.1074/jbc.M412418200  1
2005 Shenoy SK, Lefkowitz RJ. Receptor regulation: β-arrestin moves up a notch Nature Cell Biology. 7: 1159-1161. DOI: 10.1038/ncb1205-1159  0.44
2004 Shenoy SK, Lefkowitz RJ. Resonating to the music of ubiquitination. Nature Methods. 1: 191-3. PMID 15782194 DOI: 10.1038/nmeth1204-191  1
2004 Xiao K, Shenoy SK, Nobles K, Lefkowitz RJ. Activation-dependent conformational changes in {beta}-arrestin 2. The Journal of Biological Chemistry. 279: 55744-53. PMID 15501822 DOI: 10.1074/jbc.M409785200  1
2004 Ge L, Shenoy SK, Lefkowitz RJ, DeFea K. Constitutive protease-activated receptor-2-mediated migration of MDA MB-231 breast cancer cells requires both beta-arrestin-1 and -2. The Journal of Biological Chemistry. 279: 55419-24. PMID 15489220 DOI: 10.1074/jbc.M410312200  1
2004 Usui I, Imamura T, Huang J, Satoh H, Shenoy SK, Lefkowitz RJ, Hupfeld CJ, Olefsky JM. beta-arrestin-1 competitively inhibits insulin-induced ubiquitination and degradation of insulin receptor substrate 1. Molecular and Cellular Biology. 24: 8929-37. PMID 15456867 DOI: 10.1128/MCB.24.20.8929-8937.2004  1
2004 Ahn S, Shenoy SK, Wei H, Lefkowitz RJ. Differential kinetic and spatial patterns of beta-arrestin and G protein-mediated ERK activation by the angiotensin II receptor. The Journal of Biological Chemistry. 279: 35518-25. PMID 15205453 DOI: 10.1074/jbc.M405878200  1
2003 Martin NP, Lefkowitz RJ, Shenoy SK. Regulation of V2 vasopressin receptor degradation by agonist-promoted ubiquitination. The Journal of Biological Chemistry. 278: 45954-9. PMID 12960162 DOI: 10.1074/jbc.M308285200  1
2003 Shenoy SK, Lefkowitz RJ. Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling. The Biochemical Journal. 375: 503-15. PMID 12959637 DOI: 10.1042/BJ20031076  1
2003 Wei H, Ahn S, Shenoy SK, Karnik SS, Hunyady L, Luttrell LM, Lefkowitz RJ. Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2. Proceedings of the National Academy of Sciences of the United States of America. 100: 10782-7. PMID 12949261 DOI: 10.1073/pnas.1834556100  1
2003 Shenoy SK, Lefkowitz RJ. Trafficking patterns of beta-arrestin and G protein-coupled receptors determined by the kinetics of beta-arrestin deubiquitination. The Journal of Biological Chemistry. 278: 14498-506. PMID 12574160 DOI: 10.1074/jbc.M209626200  1
2002 Lin FT, Chen W, Shenoy S, Cong M, Exum ST, Lefkowitz RJ. Phosphorylation of beta-arrestin2 regulates its function in internalization of beta(2)-adrenergic receptors. Biochemistry. 41: 10692-9. PMID 12186555 DOI: 10.1021/bi025705n  1
2001 Shenoy SK, McDonald PH, Kohout TA, Lefkowitz RJ. Regulation of receptor fate by ubiquitination of activated beta 2-adrenergic receptor and beta-arrestin. Science (New York, N.Y.). 294: 1307-13. PMID 11588219 DOI: 10.1126/science.1063866  1
2000 Tso SC, Shenoy SK, Quinn BN, Yu L. Subunit IV of cytochrome bc1 complex from Rhodobacter sphaeroides. Localization of regions essential for interaction with the three-subunit core complex. The Journal of Biological Chemistry. 275: 15287-94. PMID 10748084 DOI: 10.1074/jbc.M907367199  1
1999 Yu L, Tso SC, Shenoy SK, Quinn BN, Xia D. The role of the supernumerary subunit of Rhodobacter sphaeroides cytochrome bc1 complex. Journal of Bioenergetics and Biomembranes. 31: 251-7. PMID 10591531 DOI: 10.1023/A:1005423913639  1
1999 Yu CA, Tian H, Zhang L, Deng KP, Shenoy SK, Yu L, Xia D, Kim H, Deisenhofer J. Structural basis of multifunctional bovine mitochondrial cytochrome bc1 complex. Journal of Bioenergetics and Biomembranes. 31: 191-9. PMID 10591525 DOI: 10.1023/A:1005411510913  1
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