Nathaniel Safren, Ph.D. - Publications

2014 Neuroscience University of Maryland School of Medicine, Baltimore, MD, United States 
Neuroscience Biology, Cell Biology, Biochemistry

13 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Safren N, Sharkey LM, Barmada SJ. Neuronal Puncta/Aggregate Formation by WT and Mutant UBQLN2. Methods in Molecular Biology (Clifton, N.J.). 2551: 561-573. PMID 36310225 DOI: 10.1007/978-1-0716-2597-2_34  0.398
2022 Mohan HM, Trzeciakiewicz H, Pithadia A, Crowley EV, Pacitto R, Safren N, Trotter B, Zhang C, Zhou X, Zhang Y, Basrur V, Paulson HL, Sharkey LM. RTL8 promotes nuclear localization of UBQLN2 to subnuclear compartments associated with protein quality control. Cellular and Molecular Life Sciences : Cmls. 79: 176. PMID 35247097 DOI: 10.1007/s00018-022-04170-z  0.322
2021 Safren N, Tank EM, Malik AM, Chua JP, Santoro N, Barmada SJ. Development of a specific live-cell assay for native autophagic flux. The Journal of Biological Chemistry. 101003. PMID 34303705 DOI: 10.1016/j.jbc.2021.101003  0.387
2021 Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, Abdoli A, Abel S, Abeliovich H, Abildgaard MH, Abudu YP, Acevedo-Arozena A, Adamopoulos IE, Adeli K, Adolph TE, Adornetto A, Aflaki E, ... ... Safren N, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 1-382. PMID 33634751 DOI: 10.1080/15548627.2020.1797280  0.395
2021 Gerson JE, Linton H, Xing J, Sutter AB, Kakos FS, Ryou J, Liggans N, Sharkey LM, Safren N, Paulson HL, Ivanova MI. Shared and divergent phase separation and aggregation properties of brain-expressed ubiquilins. Scientific Reports. 11: 287. PMID 33431932 DOI: 10.1038/s41598-020-78775-4  0.301
2020 Gerson JE, Safren N, Fischer S, Patel R, Crowley EV, Welday JP, Windle AK, Barmada S, Paulson HL, Sharkey LM. Ubiquilin-2 differentially regulates polyglutamine disease proteins. Human Molecular Genetics. PMID 32681165 DOI: 10.1093/hmg/ddaa152  0.464
2018 Sharkey LM, Safren N, Pithadia AS, Gerson JE, Dulchavsky M, Fischer S, Patel R, Lantis G, Ashraf N, Kim JH, Meliki A, Minakawa EN, Barmada SJ, Ivanova MI, Paulson HL. Mutant UBQLN2 promotes toxicity by modulating intrinsic self-assembly. Proceedings of the National Academy of Sciences of the United States of America. PMID 30333186 DOI: 10.1073/pnas.1810522115  0.328
2017 Al-Ramahi I, Giridharan SSP, Chen YC, Patnaik S, Safren N, Hasegawa J, de Haro M, Wagner Gee AK, Titus SA, Jeong H, Clarke J, Krainc D, Zheng W, Irvine RF, Barmada S, et al. Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein. Elife. 6. PMID 29256861 DOI: 10.7554/Elife.29123  0.394
2017 Gupta R, Lan M, Mojsilovic-Petrovic J, Choi WH, Safren N, Barmada S, Lee MJ, Kalb R. The Proline/Arginine Dipeptide from Hexanucleotide Repeat Expanded C9ORF72 Inhibits the Proteasome. Eneuro. 4. PMID 28197542 DOI: 10.1523/ENEURO.0249-16.2017  0.336
2016 Le NT, Chang L, Kovlyagina I, Georgiou P, Safren N, Braunstein KE, Kvarta MD, Van Dyke AM, LeGates TA, Philips T, Morrison BM, Thompson SM, Puche AC, Gould TD, Rothstein JD, et al. Motor neuron disease, TDP-43 pathology, and memory deficits in mice expressing ALS-FTD-linked UBQLN2 mutations. Proceedings of the National Academy of Sciences of the United States of America. PMID 27834214 DOI: 10.1073/Pnas.1608432113  0.531
2015 Safren N, Chang L, Dziki KM, Monteiro MJ. Signature changes in ubiquilin expression in the R6/2 mouse model of Huntington's disease. Brain Research. 1597: 37-46. PMID 25511991 DOI: 10.1016/J.Brainres.2014.12.008  0.512
2014 Safren N, El Ayadi A, Chang L, Terrillion CE, Gould TD, Boehning DF, Monteiro MJ. Ubiquilin-1 overexpression increases the lifespan and delays accumulation of Huntingtin aggregates in the R6/2 mouse model of Huntington's disease. Plos One. 9: e87513. PMID 24475300 DOI: 10.1371/Journal.Pone.0087513  0.522
2012 Brettschneider J, Van Deerlin VM, Robinson JL, Kwong L, Lee EB, Ali YO, Safren N, Monteiro MJ, Toledo JB, Elman L, McCluskey L, Irwin DJ, Grossman M, Molina-Porcel L, Lee VM, et al. Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion. Acta Neuropathologica. 123: 825-39. PMID 22426854 DOI: 10.1007/S00401-012-0970-Z  0.487
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