| Year |
Citation |
Score |
| 2023 |
Keegan AP, Stough C, Paris D, Luis CA, Abdullah L, Ait-Ghezala G, Chaykin J, Crawford F, Mullan M. Baseline serum brain-derived neurotrophic factor association with future cognition in community-dwelling older adults undergoing annual memory screening. Neurological Research. 1-8. PMID 38095353 DOI: 10.1080/01616412.2023.2294581 |
0.376 |
|
| 2023 |
Nkiliza A, Huguenard CJC, Aldrich GJ, Ferguson S, Cseresznye A, Darcey T, Evans JE, Dretsch M, Mullan M, Crawford F, Abdullah L. Levels of Arachidonic Acid-Derived Oxylipins and Anandamide Are Elevated Among Military ɛ4 Carriers With a History of Mild Traumatic Brain Injury and Post-Traumatic Stress Disorder Symptoms. Neurotrauma Reports. 4: 643-654. PMID 37786567 DOI: 10.1089/neur.2023.0045 |
0.398 |
|
| 2023 |
Eisenbaum M, Pearson A, Ortiz C, Mullan M, Crawford F, Ojo J, Bachmeier C. ApoE4 expression disrupts tau uptake, trafficking, and clearance in astrocytes. Glia. PMID 37668005 DOI: 10.1002/glia.24469 |
0.49 |
|
| 2023 |
McCartan R, Gratkowski A, Browning M, Hahn-Townsend C, Ferguson S, Morin A, Bachmeier C, Pearson A, Brown L, Mullan M, Crawford F, Tzekov R, Mouzon B. Human amnionic progenitor cell secretome mitigates the consequence of traumatic optic neuropathy in a mouse model. Molecular Therapy. Methods & Clinical Development. 29: 303-318. PMID 37359418 DOI: 10.1016/j.omtm.2023.04.002 |
0.369 |
|
| 2023 |
Pearson A, Ortiz C, Eisenbaum M, Arrate C, Browning M, Mullan M, Bachmeier C, Crawford F, Ojo JO. Deletion of PTEN in microglia ameliorates chronic neuroinflammation following repetitive mTBI. Molecular and Cellular Neurosciences. 103855. PMID 37084991 DOI: 10.1016/j.mcn.2023.103855 |
0.416 |
|
| 2023 |
Keegan AP, Stough C, Paris D, Luis CA, Abdullah L, Ait-Ghezala G, Crawford F, Mullan M. supplementation has no effect on serum brain-derived neurotrophic factor levels but beneficially modulates nuclear factor kappa B and cyclic AMP response element-binding protein levels in healthy elderly subjects. Journal of Clinical and Translational Research. 9: 50-58. PMID 37032999 |
0.398 |
|
| 2023 |
Huguenard CJC, Cseresznye A, Darcey T, Nkiliza A, Evans JE, Hazen SL, Mullan M, Crawford F, Abdullah L. Age and affect L-carnitine system metabolites in the brain in the APOE-TR model. Frontiers in Aging Neuroscience. 14: 1059017. PMID 36688151 DOI: 10.3389/fnagi.2022.1059017 |
0.437 |
|
| 2022 |
Huguenard CJC, Cseresznye A, Evans JE, Darcey T, Nkiliza A, Keegan AP, Luis C, Bennett DA, Arvanitakis Z, Yassine HN, Mullan M, Crawford F, Abdullah L. APOE ε4 and Alzheimer's disease diagnosis associated differences in L-carnitine, GBB, TMAO, and acylcarnitines in blood and brain. Current Research in Translational Medicine. 71: 103362. PMID 36436355 DOI: 10.1016/j.retram.2022.103362 |
0.507 |
|
| 2022 |
Ferguson S, McCartan R, Browning M, Hahn-Townsend C, Gratkowski A, Morin A, Abdullah L, Ait-Ghezala G, Ojo J, Sullivan K, Mullan M, Crawford F, Mouzon B. Impact of gulf war toxic exposures after mild traumatic brain injury. Acta Neuropathologica Communications. 10: 147. PMID 36258255 DOI: 10.1186/s40478-022-01449-x |
0.397 |
|
| 2022 |
Morin A, Davis R, Darcey T, Mullan M, Mouzon B, Crawford F. Subacute and chronic proteomic and phosphoproteomic analyses of a mouse model of traumatic brain injury at two timepoints and comparison with chronic traumatic encephalopathy in human samples. Molecular Brain. 15: 62. PMID 35850691 DOI: 10.1186/s13041-022-00945-4 |
0.424 |
|
| 2022 |
Keegan AP, Joshi U, Abdullah L, Paris D, Darcey T, Niedospial D, Davis LA, Crawford F, Mullan M. Characterization of immune profile in an aging multiple sclerosis clinic population. Multiple Sclerosis and Related Disorders. 63: 103818. PMID 35523060 DOI: 10.1016/j.msard.2022.103818 |
0.326 |
|
| 2022 |
Menden A, Hall D, Hahn-Townsend C, Broedlow CA, Joshi U, Pearson A, Crawford F, Evans JE, Klatt N, Crynen S, Mullan M, Ait-Ghezala G. Exogenous lipase administration alters gut microbiota composition and ameliorates Alzheimer's disease-like pathology in APP/PS1 mice. Scientific Reports. 12: 4797. PMID 35314754 DOI: 10.1038/s41598-022-08840-7 |
0.521 |
|
| 2022 |
Oberlin S, Nkiliza A, Parks M, Evans JE, Klimas N, Keegan AP, Sullivan K, Krengel MH, Mullan M, Crawford F, Abdullah L. Sex-specific differences in plasma lipid profiles are associated with Gulf War Illness. Journal of Translational Medicine. 20: 73. PMID 35123492 DOI: 10.1186/s12967-022-03272-3 |
0.364 |
|
| 2021 |
Eisenbaum M, Pearson A, Gratkowski A, Mouzon B, Mullan M, Crawford F, Ojo J, Bachmeier C. Influence of traumatic brain injury on extracellular tau elimination at the blood-brain barrier. Fluids and Barriers of the Cns. 18: 48. PMID 34702292 DOI: 10.1186/s12987-021-00283-y |
0.441 |
|
| 2021 |
Nkiliza A, Parks M, Cseresznye A, Oberlin S, Evans JE, Darcey T, Aenlle K, Niedospial D, Mullan M, Crawford F, Klimas N, Abdullah L. Sex-specific plasma lipid profiles of ME/CFS patients and their association with pain, fatigue, and cognitive symptoms. Journal of Translational Medicine. 19: 370. PMID 34454515 DOI: 10.1186/s12967-021-03035-6 |
0.355 |
|
| 2021 |
Ojo JO, Reed JM, Crynen G, Vallabhaneni P, Evans J, Shackleton B, Eisenbaum M, Ringland C, Edsell A, Mullan M, Crawford F, Bachmeier C. APOE genotype dependent molecular abnormalities in the cerebrovasculature of Alzheimer's disease and age-matched non-demented brains. Molecular Brain. 14: 110. PMID 34238312 DOI: 10.1186/s13041-021-00803-9 |
0.451 |
|
| 2021 |
Nkiliza A, Joshi U, Evans JE, Ait-Ghezala G, Parks M, Crawford F, Mullan M, Abdullah L. Adaptive Immune Responses Associated with the Central Nervous System Pathology of Gulf War Illness. Neuroscience Insights. 16: 26331055211018458. PMID 34104887 DOI: 10.1177/26331055211018458 |
0.359 |
|
| 2021 |
Ojo JO, Reed JM, Crynen G, Vallabhaneni P, Evans J, Shackleton B, Eisenbaum M, Ringland C, Edsell A, Mullan M, Crawford F, Bachmeier C. Molecular Pathobiology of the Cerebrovasculature in Aging and in Alzheimers Disease Cases With Cerebral Amyloid Angiopathy. Frontiers in Aging Neuroscience. 13: 658605. PMID 34079449 DOI: 10.3389/fnagi.2021.658605 |
0.503 |
|
| 2021 |
Ringland C, Schweig JE, Eisenbaum M, Paris D, Ait-Ghezala G, Mullan M, Crawford F, Abdullah L, Bachmeier C. MMP9 modulation improves specific neurobehavioral deficits in a mouse model of Alzheimer's disease. Bmc Neuroscience. 22: 39. PMID 34034683 DOI: 10.1186/s12868-021-00643-2 |
0.478 |
|
| 2021 |
Menden A, Crynen S, Mathura V, Paris D, Crawford F, Mullan M, Ait-Ghezala G. Novel, natural allosteric inhibitors and enhancers of Candida rugosa lipase activity. Bioorganic Chemistry. 109: 104732. PMID 33639364 DOI: 10.1016/j.bioorg.2021.104732 |
0.355 |
|
| 2020 |
Ojo J, Eisenbaum M, Shackleton B, Lynch C, Joshi U, Saltiel N, Pearson A, Ringland C, Paris D, Mouzon B, Mullan M, Crawford F, Bachmeier C. Mural cell dysfunction leads to altered cerebrovascular tau uptake following repetitive head trauma. Neurobiology of Disease. 105237. PMID 33383188 DOI: 10.1016/j.nbd.2020.105237 |
0.47 |
|
| 2020 |
Pearson A, Ajoy R, Crynen G, Reed JM, Algamal M, Mullan M, Purohit D, Crawford F, Ojo JO. Molecular abnormalities in autopsied brain tissue from the inferior horn of the lateral ventricles of nonagenarians and Alzheimer disease patients. Bmc Neurology. 20: 317. PMID 32854643 DOI: 10.1186/S12883-020-01849-3 |
0.531 |
|
| 2020 |
Menden A, Hall D, Broedlow CA, Darcey T, Crawford F, Klatt N, Crynen S, Mullan M, Ait-Ghezala G. Candida rugosa lipase alters the gastrointestinal environment in wild-type mice. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 130: 110579. PMID 32771891 DOI: 10.1016/J.Biopha.2020.110579 |
0.465 |
|
| 2020 |
Ringland C, Schweig JE, Paris D, Shackleton B, Lynch CE, Eisenbaum M, Mullan M, Crawford F, Abdullah L, Bachmeier C. Apolipoprotein E isoforms differentially regulate matrix metallopeptidase 9 function in Alzheimer's disease. Neurobiology of Aging. 95: 56-68. PMID 32758917 DOI: 10.1016/J.Neurobiolaging.2020.06.018 |
0.547 |
|
| 2020 |
Algamal M, Pearson AJ, Hahn-Townsend C, Burca I, Mullan M, Crawford F, Ojo JO. Repeated unpredictable stress and social isolation induce chronic HPA axis dysfunction and persistent abnormal fear memory. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 110035. PMID 32682873 DOI: 10.1016/J.Pnpbp.2020.110035 |
0.441 |
|
| 2020 |
Dyer AH, Murphy C, Briggs R, Lawlor B, Kennelly SP, Lawlor B, Segurado R, Kennelly S, Marcel GM, Howard R, Pasquier F, Borjesson-Hanson A, Tsolaki M, Lucca U, ... ... Mullan M, et al. Antidepressant Use and Orthostatic Hypotension in Older Adults Living with Mild-to-Moderate Alzheimer Disease. International Journal of Geriatric Psychiatry. PMID 32668020 DOI: 10.1002/gps.5377 |
0.486 |
|
| 2020 |
Joshi U, Evans JE, Pearson A, Saltiel N, Cseresznye A, Darcey T, Ojo J, Keegan AP, Oberlin S, Mouzon B, Paris D, Klimas N, Sullivan K, Mullan M, Crawford F, et al. Targeting sirtuin activity with nicotinamide riboside reduces neuroinflammation in a GWI mouse model. Neurotoxicology. PMID 32343995 DOI: 10.1016/J.Neuro.2020.04.006 |
0.487 |
|
| 2020 |
Schweig JE, Yao H, Jin C, Crawford F, Mullan M, Paris D. Neuronal Spleen tyrosine kinase (SYK) mediates cytokine release in Transgenic Tau P301S mice organotypic brain slice cultures. Neuroscience Letters. 134992. PMID 32334108 DOI: 10.1016/J.Neulet.2020.134992 |
0.564 |
|
| 2020 |
Ojo JO, Crynen G, Algamal M, Vallabhaneni P, Leary P, Mouzon B, Reed JM, Mullan M, Crawford F. Unbiased Proteomic Approach Identifies Pathobiological Profiles in the Brains of Preclinical Models of Repetitive Mild Traumatic Brain Injury, Tauopathy, and Amyloidosis. Asn Neuro. 12: 1759091420914768. PMID 32241177 DOI: 10.1177/1759091420914768 |
0.479 |
|
| 2020 |
Abdullah L, Crawford F, Tsolaki M, Börjesson-Hanson A, Olde Rikkert M, Pasquier F, Wallin A, Kennelly S, Ait-Ghezala G, Paris D, Hendrix S, Blennow K, Lawlor B, Mullan M. The Influence of Baseline Alzheimer's Disease Severity on Cognitive Decline and CSF Biomarkers in the NILVAD Trial. Frontiers in Neurology. 11: 149. PMID 32210906 DOI: 10.3389/Fneur.2020.00149 |
0.572 |
|
| 2020 |
Huguenard CJC, Cseresznye A, Evans JE, Oberlin S, Langlois H, Ferguson S, Darcey T, Nkiliza A, Dretsch M, Mullan M, Crawford F, Abdullah L. Plasma Lipidomic Analyses in Cohorts With mTBI and/or PTSD Reveal Lipids Differentially Associated With Diagnosis and ε4 Carrier Status. Frontiers in Physiology. 11: 12. PMID 32082186 DOI: 10.3389/Fphys.2020.00012 |
0.465 |
|
| 2020 |
Emmerich T, Abdullah L, Ojo J, Mouzon B, Nguyen T, Crynen G, Evans JE, Reed J, Mullan M, Crawford F. Correction to: Mild TBI Results in a Long-Term Decrease in Circulating Phospholipids in a Mouse Model of Injury. Neuromolecular Medicine. PMID 32078110 DOI: 10.1007/S12017-020-08593-4 |
0.451 |
|
| 2019 |
Yao H, Coppola K, Schweig JE, Crawford F, Mullan M, Paris D. Distinct Signaling Pathways Regulate TREM2 Phagocytic and NFκB Antagonistic Activities. Frontiers in Cellular Neuroscience. 13: 457. PMID 31649511 DOI: 10.3389/Fncel.2019.00457 |
0.525 |
|
| 2019 |
Menden A, Hall D, Paris D, Mathura V, Crawford F, Mullan M, Crynen S, Ait-Ghezala G. A fast, miniaturised assay developed for quantification of lipase enzyme activity. Journal of Enzyme Inhibition and Medicinal Chemistry. 34: 1474-1480. PMID 31414611 DOI: 10.1080/14756366.2019.1651312 |
0.42 |
|
| 2019 |
Joshi U, Evans JE, Joseph R, Emmerich T, Saltiel N, Lungmus C, Oberlin S, Langlois H, Ojo J, Mouzon B, Paris D, Mullan M, Jin C, Klimas N, Sullivan K, et al. Author Correction: Oleoylethanolamide treatment reduces neurobehavioral deficits and brain pathology in a mouse model of Gulf War Illness. Scientific Reports. 9: 11011. PMID 31337781 DOI: 10.1038/S41598-019-46255-Z |
0.456 |
|
| 2019 |
Joshi U, Pearson A, Evans JE, Langlois H, Saltiel N, Ojo J, Klimas N, Sullivan K, Keegan AP, Oberlin S, Darcey T, Cseresznye A, Raya B, Paris D, Hammock B, ... ... Mullan M, et al. A permethrin metabolite is associated with adaptive immune responses in Gulf War Illness. Brain, Behavior, and Immunity. PMID 31325531 DOI: 10.1016/J.Bbi.2019.07.015 |
0.481 |
|
| 2019 |
Schweig JE, Yao H, Coppola K, Jin C, Crawford F, Mullan M, Paris D. Spleen tyrosine kinase (SYK) blocks autophagic Tau degradation and . The Journal of Biological Chemistry. PMID 31324720 DOI: 10.1074/Jbc.Ra119.008033 |
0.58 |
|
| 2019 |
Shackleton B, Ringland C, Abdullah L, Mullan M, Crawford F, Bachmeier C. Influence of Matrix Metallopeptidase 9 on Beta-Amyloid Elimination Across the Blood-Brain Barrier. Molecular Neurobiology. PMID 31209784 DOI: 10.1007/S12035-019-01672-Z |
0.556 |
|
| 2019 |
Shea D, Hsu CC, Bi TM, Paranjapye N, Childers MC, Cochran J, Tomberlin CP, Wang L, Paris D, Zonderman J, Varani G, Link CD, Mullan M, Daggett V. α-Sheet secondary structure in amyloid β-peptide drives aggregation and toxicity in Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 31004062 DOI: 10.1073/Pnas.1820585116 |
0.371 |
|
| 2019 |
Algamal M, Saltiel N, Pearson AJ, Ager B, Burca I, Mouzon BC, Diamond D, Mullan M, Ojo J, Crawford FC. Impact of repetitive mild traumatic brain injury on behavioral and hippocampal deficits in a mouse model of chronic stress. Journal of Neurotrauma. PMID 30963958 DOI: 10.1089/Neu.2018.6314 |
0.395 |
|
| 2019 |
Ojo JO, Algamal M, Leary P, Abdullah L, Mouzon B, Evans JE, Mullan M, Crawford F. Converging and Differential Brain Phospholipid Dysregulation in the Pathogenesis of Repetitive Mild Traumatic Brain Injury and Alzheimer's Disease. Frontiers in Neuroscience. 13: 103. PMID 30837829 DOI: 10.3389/Fnins.2019.00103 |
0.546 |
|
| 2019 |
Muza P, Bachmeier C, Mouzon B, Algamal M, Rafi NG, Lungmus C, Abdullah L, Evans JE, Ferguson S, Mullan M, Crawford F, Ojo JO. APOE Genotype Specific Effects on the Early Neurodegenerative Sequelae Following Chronic Repeated Mild Traumatic Brain Injury. Neuroscience. PMID 30711612 DOI: 10.1016/J.Neuroscience.2019.01.049 |
0.484 |
|
| 2019 |
Huguenard C, Cseresznye A, Evans J, Crawford F, Mullan M, Abdullah L. P2-251: Serum Acylcarnitine Lipids As Biomarkers Of Preclinical Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2658 |
0.521 |
|
| 2018 |
Ojo JO, Crynen G, Reed JM, Ajoy R, Vallabhaneni P, Algamal M, Leary P, Rafi NG, Mouzon B, Mullan M, Crawford F. Unbiased Proteomic Approach Identifies Unique and Coincidental Plasma Biomarkers in Repetitive mTBI and AD Pathogenesis. Frontiers in Aging Neuroscience. 10: 405. PMID 30618712 DOI: 10.3389/Fnagi.2018.00405 |
0.5 |
|
| 2018 |
Ojo JO, Algamal M, Leary P, Abdullah L, Mouzon B, Evans JE, Mullan M, Crawford F. Disruption in Brain Phospholipid Content in a Humanized Tau Transgenic Model Following Repetitive Mild Traumatic Brain Injury. Frontiers in Neuroscience. 12: 893. PMID 30564087 DOI: 10.3389/Fnins.2018.00893 |
0.454 |
|
| 2018 |
Ojo JO, Leary P, Lungmus C, Algamal M, Mouzon B, Bachmeier C, Mullan M, Stewart W, Crawford F. Subchronic Pathobiological Response Following Chronic Repetitive Mild Traumatic Brain Injury in an Aged Preclinical Model of Amyloid Pathogenesis. Journal of Neuropathology and Experimental Neurology. PMID 30395237 DOI: 10.1093/Jnen/Nly101 |
0.528 |
|
| 2018 |
Morin A, Mouzon B, Ferguson S, Paris D, Saltiel N, Lungmus C, Mullan M, Crawford F. Treatment With Nilvadipine Mitigates Inflammatory Pathology and Improves Spatial Memory in Aged hTau Mice After Repetitive Mild TBI. Frontiers in Aging Neuroscience. 10: 292. PMID 30364309 DOI: 10.3389/Fnagi.2018.00292 |
0.531 |
|
| 2018 |
Lawlor B, Segurado R, Kennelly S, Olde Rikkert MGM, Howard R, Pasquier F, Börjesson-Hanson A, Tsolaki M, Lucca U, Molloy DW, Coen R, Riepe MW, Kálmán J, Kenny RA, Cregg F, ... ... Mullan M, et al. Nilvadipine in mild to moderate Alzheimer disease: A randomised controlled trial. Plos Medicine. 15: e1002660. PMID 30248105 DOI: 10.1371/Journal.Pmed.1002660 |
0.549 |
|
| 2018 |
Joshi U, Evans JE, Joseph R, Emmerich T, Saltiel N, Lungmus C, Oberlin S, Langlois H, Ojo J, Mouzon B, Paris D, Mullan M, Jin C, Klimas N, Sullivan K, et al. Oleoylethanolamide treatment reduces neurobehavioral deficits and brain pathology in a mouse model of Gulf War Illness. Scientific Reports. 8: 12921. PMID 30150699 DOI: 10.1038/S41598-018-31242-7 |
0.498 |
|
| 2018 |
Algamal M, Ojo JO, Lungmus CP, Muza P, Cammarata C, Owens MJ, Mouzon BC, Diamond DM, Mullan M, Crawford F. Chronic Hippocampal Abnormalities and Blunted HPA Axis in an Animal Model of Repeated Unpredictable Stress. Frontiers in Behavioral Neuroscience. 12: 150. PMID 30079015 DOI: 10.3389/Fnbeh.2018.00150 |
0.389 |
|
| 2018 |
Mouzon BC, Bachmeier C, Ojo J, Acker C, Ferguson S, Crynen G, Davies P, Mullan M, Stewart W, Crawford FC. Chronic white matter degeneration, but no tau pathology at 1-year post-repetitive mild traumatic brain injury in tau transgenic model. Journal of Neurotrauma. PMID 29993324 DOI: 10.1089/Neu.2018.5720 |
0.506 |
|
| 2018 |
Mouzon B, Saltiel N, Ferguson S, Ojo J, Lungmus C, Lynch C, Algamal M, Morin A, Carper B, Bieler G, Mufson EJ, Stewart W, Mullan M, Crawford F. Impact of age on acute post-TBI neuropathology in mice expressing humanized tau: a Chronic Effects of Neurotrauma Consortium Study. Brain Injury. 1-10. PMID 29927671 DOI: 10.1080/02699052.2018.1486457 |
0.417 |
|
| 2018 |
Mouzon BC, Bachmeier C, Ojo JO, Acker CM, Ferguson S, Paris D, Ait-Ghezala G, Crynen G, Davies P, Mullan M, Stewart W, Crawford F. Lifelong behavioral and neuropathological consequences of repetitive mild traumatic brain injury. Annals of Clinical and Translational Neurology. 5: 64-80. PMID 29376093 DOI: 10.1002/Acn3.510 |
0.484 |
|
| 2017 |
Ferguson SA, Mouzon BC, Lynch C, Lungmus C, Morin A, Crynen G, Carper B, Bieler G, Mufson EJ, Stewart W, Mullan M, Crawford F. Negative Impact of Female Sex on Outcomes from Repetitive Mild Traumatic Brain Injury in hTau Mice Is Age Dependent: A Chronic Effects of Neurotrauma Consortium Study. Frontiers in Aging Neuroscience. 9: 416. PMID 29311903 DOI: 10.3389/Fnagi.2017.00416 |
0.501 |
|
| 2017 |
Schweig JE, Yao H, Beaulieu-Abdelahad D, Ait-Ghezala G, Mouzon B, Crawford F, Mullan M, Paris D. Alzheimer's disease pathological lesions activate the spleen tyrosine kinase. Acta Neuropathologica Communications. 5: 69. PMID 28877763 DOI: 10.1186/S40478-017-0472-2 |
0.588 |
|
| 2017 |
Keegan AP, Paris D, Luis CA, Abdullah L, Ait-Ghezala G, Beaulieu-Abdelahad D, Pryor M, Chaykin J, Crynen G, Crawford F, Mullan M. Plasma cytokine IL-6 levels and subjective cognitive decline: preliminary findings. International Journal of Geriatric Psychiatry. PMID 28639714 DOI: 10.1002/Gps.4752 |
0.504 |
|
| 2017 |
Emmerich T, Zakirova Z, Klimas N, Sullivan K, Shetty AK, Evans JE, Ait-Ghezala G, Laco GS, Hattiangady B, Shetty GA, Mullan M, Crynen G, Abdullah L, Crawford F. Phospholipid profiling of plasma from GW veterans and rodent models to identify potential biomarkers of Gulf War Illness. Plos One. 12: e0176634. PMID 28453542 DOI: 10.1371/Journal.Pone.0176634 |
0.475 |
|
| 2017 |
Zakirova Z, Reed J, Crynen G, Horne L, Hassan S, Mathura V, Mullan M, Crawford F, Ait-Ghezala G. Complementary proteomic approaches reveal mitochondrial dysfunction, immune and inflammatory dysregulation in a mouse model of gulf war illness. Proteomics. Clinical Applications. PMID 28371386 DOI: 10.1002/Prca.201600190 |
0.457 |
|
| 2017 |
Shen Y, Wang H, Sun Q, Yao H, Keegan AP, Mullan M, Wilson J, Lista S, Leyhe T, Laske C, Rujescu D, Levey A, Wallin A, Blennow K, Li R, et al. Increased Plasma Beta-Secretase 1 May Predict Conversion to Alzheimer's Disease Dementia in Individuals With Mild Cognitive Impairment. Biological Psychiatry. PMID 28359566 DOI: 10.1016/J.Biopsych.2017.02.007 |
0.404 |
|
| 2017 |
Abdullah L, Evans JE, Emmerich T, Crynen G, Shackleton B, Keegan AP, Luis C, Tai L, LaDu MJ, Mullan M, Crawford F, Bachmeier C. APOE ε4 specific imbalance of arachidonic acid and docosahexaenoic acid in serum phospholipids identifies individuals with preclinical Mild Cognitive Impairment/Alzheimer's Disease. Aging. PMID 28333036 DOI: 10.18632/aging.101203 |
0.51 |
|
| 2017 |
Ojo J, Algamal M, Abdullah L, Crawford F, Evans JE, Mullan M. Phospholipid Disruption In The Brain Links Mouse Models Of Repetitive Mild Traumatic Brain Injury And Alzheimer’S Disease Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.275 |
0.492 |
|
| 2017 |
Abdullah L, Evans JE, Shackleton B, Ojo J, Mullan M, Crawford F, Bachmeier C. Apoe-E4 Dependent Deficits In Dha Phospholipids And Transporters In Alzheimer’S Disease Patients With Severe Cerebral Amyloid Angiopathy Alzheimers & Dementia. 13: 1303. DOI: 10.1016/J.Jalz.2017.06.1986 |
0.52 |
|
| 2016 |
Abdullah L, Evans JE, Joshi U, Crynen G, Reed J, Mouzon B, Baumann S, Montague H, Zakirova Z, Emmerich T, Bachmeier C, Klimas N, Sullivan K, Mullan M, Ait-Ghezala G, et al. Long title: Translational potential of long-term decreases in mitochondrial lipids in a mouse model of Gulf War Illness. Toxicology. PMID 27984134 DOI: 10.1016/j.tox.2016.10.012 |
0.418 |
|
| 2016 |
Abdullah L, Evans JE, Joshi U, Crynen G, Reed J, Mouzon B, Baumann S, Montague H, Zakirova Z, Emmerich T, Bachmeier C, Klimas N, Sullivan K, Mullan M, Ait-Ghezala G, et al. Translational potential of long-term decreases in mitochondrial lipids in a mouse model of Gulf War Illness. Toxicology. 372: 22-33. PMID 27931520 DOI: 10.1016/J.Tox.2016.10.012 |
0.489 |
|
| 2016 |
Ferguson S, Mouzon BC, Paris D, Aponte D, Abdullah L, Stewart W, Mullan M, Crawford FC. Acute or delayed treatment with anatabine improves spatial memory and reduces pathological sequelae at chronic timepoints after repetitive mild TBI. Journal of Neurotrauma. PMID 27889957 DOI: 10.1089/Neu.2016.4636 |
0.486 |
|
| 2016 |
Emmerich T, Abdullah L, Ojo J, Mouzon B, Nguyen T, Laco GS, Crynen G, Evans JE, Reed J, Mullan M, Crawford F. Mild TBI Results in a Long-Term Decrease in Circulating Phospholipids in a Mouse Model of Injury. Neuromolecular Medicine. PMID 27540748 DOI: 10.1007/S12017-016-8436-4 |
0.475 |
|
| 2016 |
Meulenbroek O, O'Dwyer S, de Jong D, van Spijker G, Kennelly S, Cregg F, Olde Rikkert M, Abdullah L, Wallin A, Walsh C, Coen R, Kenny RA, Daly L, Segurado R, Borjesson-Hanson A, ... ... Mullan M, et al. European multicentre double-blind placebo-controlled trial of Nilvadipine in mild-to-moderate Alzheimer's disease-the substudy protocols: NILVAD frailty; NILVAD blood and genetic biomarkers; NILVAD cerebrospinal fluid biomarkers; NILVAD cerebral blood flow. Bmj Open. 6: e011584. PMID 27436668 DOI: 10.1136/bmjopen-2016-011584 |
0.441 |
|
| 2016 |
Ojo JO, Mouzon B, Algamal M, Leary P, Lynch C, Abdullah L, Evans J, Mullan M, Bachmeier C, Stewart W, Crawford F. Chronic Repetitive Mild Traumatic Brain Injury Results in Reduced Cerebral Blood Flow, Axonal Injury, Gliosis, and Increased T-Tau and Tau Oligomers. Journal of Neuropathology and Experimental Neurology. PMID 27251042 DOI: 10.1093/Jnen/Nlw035 |
0.456 |
|
| 2016 |
Tzekov R, Dawson C, Orlando M, Mouzon B, Reed J, Evans J, Crynen G, Mullan M, Crawford F. Sub-Chronic Neuropathological and Biochemical Changes in Mouse Visual System after Repetitive Mild Traumatic Brain Injury. Plos One. 11: e0153608. PMID 27088355 DOI: 10.1371/Journal.Pone.0153608 |
0.469 |
|
| 2016 |
Lawlor B, O'Dwyer S, Cregg F, Meulenbroek O, Wallin A, Coen R, Anne KR, Rikkert MGMO, Kennelly S, Borjesson-Hanson A, Crawford F, Mullan M, Pasquier F, Molloy W, Tsolaki M, et al. Nilvad: An Investigator Driven Phase Iii Multi Centre European Clinical Trial Of Nilvadipine In Mild To Moderate Alzheimer'S Disease Alzheimers & Dementia. 12: 424. DOI: 10.1016/J.Jalz.2016.06.805 |
0.501 |
|
| 2016 |
Paris D, Schweig J, Beaulieu-Abdelahad D, Lin Y, Mullan M, Crawford F. Regulation Of Ab Production And Tau Phosphorylation Via Syk-Dependent Mechanisms Alzheimers & Dementia. 12: 1027. DOI: 10.1016/J.Jalz.2016.06.2122 |
0.455 |
|
| 2016 |
Abdullah L, Evans J, Shackleton B, Ojo J, Nguyen T, Reed J, Mullan M, Crawford F, Bachmeier C. Apoe4 Genotype-Dependent Deficits In Dha Containing Phospholipids And Dha Transporters In The Cerebrovasculature Of Alzheimer'S Disease Patients Alzheimers & Dementia. 12: 867. DOI: 10.1016/J.Jalz.2016.06.1782 |
0.531 |
|
| 2016 |
Schweig J, Beaulieu-Abdelahad D, Lin Y, Crawford F, Paris D, Mullan M. Abnormal Accumulation Of Activated Syk In Microglia And Dystrophic Neurites In Mouse Models Of Alzheimer’S Disease Alzheimers & Dementia. 12: 859. DOI: 10.1016/J.Jalz.2016.06.1763 |
0.513 |
|
| 2016 |
Abdullah L, Evans J, Emmerich T, Nguyen T, Crynen G, Shackleton B, Reed J, Keegan AP, Luis C, Tai L, LaDu MJ, Mullan M, Crawford F, Bachmeier C. Apoe4-Specific Imbalance In Arachidonic Acid And Docosahexaenoic Acid In Serum Phospholipids From Individuals With Preclinical Mci/Ad Alzheimers & Dementia. 12: 671. DOI: 10.1016/J.Jalz.2016.06.1519 |
0.495 |
|
| 2015 |
Emmerich T, Abdullah L, Crynen G, Dretsch M, Evans J, Ait-Ghenzala G, Reed J, Montague H, Chaytow H, Mathura V, Martin J, Pelot R, Ferguson S, Bishop A, Phillips J, ... Mullan M, et al. Plasma lipidomic profiling in a military population of mTBI and PTSD with APOE ε4 dependent effect. Journal of Neurotrauma. PMID 26714394 DOI: 10.1089/Neu.2015.4061 |
0.462 |
|
| 2015 |
Ojo JO, Bachmeier C, Mouzon BC, Tzekov R, Mullan M, Davies H, Stewart MG, Crawford F. Ultrastructural Changes in the White and Gray Matter of Mice at Chronic Time Points After Repeated Concussive Head Injury. Journal of Neuropathology and Experimental Neurology. 74: 1012-35. PMID 26360375 DOI: 10.1097/Nen.0000000000000247 |
0.49 |
|
| 2015 |
Verma M, Beaulieu-Abdelahad D, Ait-Ghezala G, Li R, Crawford F, Mullan M, Paris D. Correction: Chronic Anatabine Treatment Reduces Alzheimer's Disease (AD)-Like Pathology and Improves Socio-Behavioral Deficits in a Transgenic Mouse Model of AD. Plos One. 10: e0134776. PMID 26230317 DOI: 10.1371/journal.pone.0134776 |
0.508 |
|
| 2015 |
Verma M, Beaulieu-Abdelahad D, Ait-Ghezala G, Li R, Crawford F, Mullan M, Paris D. Chronic Anatabine Treatment Reduces Alzheimer's Disease (AD)-Like Pathology and Improves Socio-Behavioral Deficits in a Transgenic Mouse Model of AD. Plos One. 10: e0128224. PMID 26010758 DOI: 10.1371/Journal.Pone.0128224 |
0.577 |
|
| 2015 |
Zakirova Z, Tweed M, Crynen G, Reed J, Abdullah L, Nissanka N, Mullan M, Mullan MJ, Mathura V, Crawford F, Ait-Ghezala G. Gulf War agent exposure causes impairment of long-term memory formation and neuropathological changes in a mouse model of Gulf War Illness. Plos One. 10: e0119579. PMID 25785457 DOI: 10.1371/Journal.Pone.0119579 |
0.46 |
|
| 2014 |
Paris D, Ait-Ghezala G, Bachmeier C, Laco G, Beaulieu-Abdelahad D, Lin Y, Jin C, Crawford F, Mullan M. The spleen tyrosine kinase (Syk) regulates Alzheimer amyloid-β production and Tau hyperphosphorylation. The Journal of Biological Chemistry. 289: 33927-44. PMID 25331948 DOI: 10.1074/Jbc.M114.608091 |
0.575 |
|
| 2014 |
Lawlor B, Kennelly S, O'Dwyer S, Cregg F, Walsh C, Coen R, Kenny RA, Howard R, Murphy C, Adams J, Daly L, Segurado R, Gaynor S, Crawford F, Mullan M, et al. NILVAD protocol: a European multicentre double-blind placebo-controlled trial of nilvadipine in mild-to-moderate Alzheimer's disease. Bmj Open. 4: e006364. PMID 25300460 DOI: 10.1136/bmjopen-2014-006364 |
0.463 |
|
| 2014 |
Abdullah L, Evans JE, Ferguson S, Mouzon B, Montague H, Reed J, Crynen G, Emmerich T, Crocker M, Pelot R, Mullan M, Crawford F. Lipidomic analyses identify injury-specific phospholipid changes 3 mo after traumatic brain injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 5311-21. PMID 25208845 DOI: 10.1096/Fj.14-258228 |
0.484 |
|
| 2014 |
Bachmeier C, Shackleton B, Ojo J, Paris D, Mullan M, Crawford F. Apolipoprotein E isoform-specific effects on lipoprotein receptor processing. Neuromolecular Medicine. 16: 686-96. PMID 25015123 DOI: 10.1007/S12017-014-8318-6 |
0.564 |
|
| 2014 |
Ojo JO, Greenberg MB, Leary P, Mouzon B, Bachmeier C, Mullan M, Diamond DM, Crawford F. Neurobehavioral, neuropathological and biochemical profiles in a novel mouse model of co-morbid post-traumatic stress disorder and mild traumatic brain injury. Frontiers in Behavioral Neuroscience. 8: 213. PMID 25002839 DOI: 10.3389/Fnbeh.2014.00213 |
0.462 |
|
| 2014 |
Tzekov R, Quezada A, Gautier M, Biggins D, Frances C, Mouzon B, Jamison J, Mullan M, Crawford F. Repetitive mild traumatic brain injury causes optic nerve and retinal damage in a mouse model. Journal of Neuropathology and Experimental Neurology. 73: 345-61. PMID 24607965 DOI: 10.1097/Nen.0000000000000059 |
0.454 |
|
| 2014 |
Tzekov R, Mullan M. Vision function abnormalities in Alzheimer disease. Survey of Ophthalmology. 59: 414-33. PMID 24309127 DOI: 10.1016/J.Survophthal.2013.10.002 |
0.369 |
|
| 2014 |
Mouzon BC, Bachmeier C, Ferro A, Ojo JO, Crynen G, Acker CM, Davies P, Mullan M, Stewart W, Crawford F. Chronic neuropathological and neurobehavioral changes in a repetitive mild traumatic brain injury model. Annals of Neurology. 75: 241-54. PMID 24243523 DOI: 10.1002/Ana.24064 |
0.423 |
|
| 2014 |
Ojo JO, Abdullah L, Evans J, Reed JM, Montague H, Mullan MJ, Crawford FC. Exposure to an organophosphate pesticide, individually or in combination with other Gulf War agents, impairs synaptic integrity and neuronal differentiation, and is accompanied by subtle microvascular injury in a mouse model of Gulf War agent exposure. Neuropathology : Official Journal of the Japanese Society of Neuropathology. 34: 109-27. PMID 24118348 DOI: 10.1111/neup.12061 |
0.404 |
|
| 2013 |
Abdullah L, Evans JE, Montague H, Reed JM, Moser A, Crynen G, Gonzalez A, Zakirova Z, Ross I, Mullan C, Mullan M, Ait-Ghezala G, Crawford F. Chronic elevation of phosphocholine containing lipids in mice exposed to Gulf War agents pyridostigmine bromide and permethrin. Neurotoxicology and Teratology. 40: 74-84. PMID 24140745 DOI: 10.1016/J.Ntt.2013.10.002 |
0.485 |
|
| 2013 |
Bachmeier C, Beaulieu-Abdelahad D, Mullan M, Paris D. Role of the cannabinoid system in the transit of beta-amyloid across the blood-brain barrier. Molecular and Cellular Neurosciences. 56: 255-62. PMID 23831388 DOI: 10.1016/J.Mcn.2013.06.004 |
0.398 |
|
| 2013 |
Paris D, Beaulieu-Abdelahad D, Mullan M, Ait-Ghezala G, Mathura V, Bachmeier C, Crawford F, Mullan MJ. Amelioration of experimental autoimmune encephalomyelitis by anatabine. Plos One. 8: e55392. PMID 23383175 DOI: 10.1371/Journal.Pone.0055392 |
0.478 |
|
| 2013 |
Ojo JO, Mouzon B, Greenberg MB, Bachmeier C, Mullan M, Crawford F. Repetitive mild traumatic brain injury augments tau pathology and glial activation in aged hTau mice. Journal of Neuropathology and Experimental Neurology. 72: 137-51. PMID 23334597 DOI: 10.1097/Nen.0B013E3182814Cdf |
0.535 |
|
| 2013 |
Paris D, Beaulieu-Abdelahad D, Abdullah L, Bachmeier C, Ait-Ghezala G, Reed J, Verma M, Crawford F, Mullan M. Anti-inflammatory activity of anatabine via inhibition of STAT3 phosphorylation. European Journal of Pharmacology. 698: 145-53. PMID 23178521 DOI: 10.1016/J.Ejphar.2012.11.017 |
0.49 |
|
| 2013 |
Bachmeier C, Beaulieu-Abdelahad D, Crawford F, Mullan M, Paris D. Stimulation of the retinoid X receptor facilitates beta-amyloid clearance across the blood-brain barrier. Journal of Molecular Neuroscience : Mn. 49: 270-6. PMID 22890420 DOI: 10.1007/S12031-012-9866-6 |
0.562 |
|
| 2013 |
Bachmeier C, Paris D, Beaulieu-Abdelahad D, Mouzon B, Mullan M, Crawford F. A multifaceted role for apoE in the clearance of beta-amyloid across the blood-brain barrier. Neuro-Degenerative Diseases. 11: 13-21. PMID 22572854 DOI: 10.1159/000337231 |
0.588 |
|
| 2013 |
Pelot RC, Reed J, Crynen G, Evans J, Hart A, Plate T, Vallabhaneni P, Abdullah L, Mullan M, Crawford F. Rapid and cost-effective purification of Endo-Lys-N from maitake (Grifola frondosa) mushrooms for proteomics applications Current Proteomics. 10: 292-297. DOI: 10.2174/15701646113106660003 |
0.399 |
|
| 2013 |
Abdullah L, Evans J, Montague H, Gonzalez A, Shah A, Kirk B, Reed J, Crynen G, Pelot R, Keegan A, Luis C, Mullan M, Crawford F. Use of lipidomics to identify novel blood-based phospholipid biomarkers that distinguish between mild cognitive impairment and early Alzheimer's disease Alzheimers & Dementia. 9: 240. DOI: 10.1016/J.Jalz.2013.05.464 |
0.516 |
|
| 2013 |
Sheinerman K, Tsivinsky V, Crawford F, Mullan M, Abdullah L, Umansky S. Early detection of Alzheimer's disease by analysis of brain-enriched miRNA biomarkers in plasma Alzheimers & Dementia. 9: 236. DOI: 10.1016/J.Jalz.2013.05.450 |
0.472 |
|
| 2012 |
Sheinerman KS, Tsivinsky VG, Crawford F, Mullan MJ, Abdullah L, Umansky SR. Plasma microRNA biomarkers for detection of mild cognitive impairment. Aging. 4: 590-605. PMID 23001356 |
0.36 |
|
| 2012 |
Mouzon B, Chaytow H, Crynen G, Bachmeier C, Stewart J, Mullan M, Stewart W, Crawford F. Repetitive mild traumatic brain injury in a mouse model produces learning and memory deficits accompanied by histological changes. Journal of Neurotrauma. 29: 2761-73. PMID 22900595 DOI: 10.1089/Neu.2012.2498 |
0.473 |
|
| 2012 |
Abdullah L, Evans JE, Bishop A, Reed JM, Crynen G, Phillips J, Pelot R, Mullan MA, Ferro A, Mullan CM, Mullan MJ, Ait-Ghezala G, Crawford FC. Lipidomic profiling of phosphocholine-containing brain lipids in mice with sensorimotor deficits and anxiety-like features after exposure to Gulf War agents. Neuromolecular Medicine. 14: 349-61. PMID 22798222 DOI: 10.1007/s12017-012-8192-z |
0.414 |
|
| 2012 |
Crawford F, Crynen G, Reed J, Mouzon B, Bishop A, Katz B, Ferguson S, Phillips J, Ganapathi V, Mathura V, Roses A, Mullan M. Identification of plasma biomarkers of TBI outcome using proteomic approaches in an APOE mouse model. Journal of Neurotrauma. 29: 246-60. PMID 21895520 DOI: 10.1089/Neu.2011.1789 |
0.484 |
|
| 2012 |
Kennelly S, Abdullah L, Kenny RA, Mathura V, Luis CA, Mouzon B, Crawford F, Mullan M, Lawlor B. Apolipoprotein E genotype-specific short-term cognitive benefits of treatment with the antihypertensive nilvadipine in Alzheimer's patients--an open-label trial. International Journal of Geriatric Psychiatry. 27: 415-22. PMID 21560164 DOI: 10.1002/Gps.2735 |
0.523 |
|
| 2011 |
Abdullah L, Crynen G, Reed J, Bishop A, Phillips J, Ferguson S, Mouzon B, Mullan M, Mathura V, Mullan M, Ait-Ghezala G, Crawford F. Proteomic CNS profile of delayed cognitive impairment in mice exposed to Gulf War agents. Neuromolecular Medicine. 13: 275-88. PMID 21986894 DOI: 10.1007/S12017-011-8160-Z |
0.488 |
|
| 2011 |
Paris D, Beaulieu-Abdelahad D, Bachmeier C, Reed J, Ait-Ghezala G, Bishop A, Chao J, Mathura V, Crawford F, Mullan M. Anatabine lowers Alzheimer's Aβ production in vitro and in vivo. European Journal of Pharmacology. 670: 384-91. PMID 21958873 DOI: 10.1016/J.Ejphar.2011.09.019 |
0.564 |
|
| 2011 |
Kennelly SP, Abdullah L, Paris D, Parish J, Mathura V, Mullan M, Crawford F, Lawlor BA, Kenny RA. Demonstration of safety in Alzheimer's patients for intervention with an anti-hypertensive drug Nilvadipine: results from a 6-week open label study. International Journal of Geriatric Psychiatry. 26: 1038-45. PMID 21905098 DOI: 10.1002/Gps.2638 |
0.52 |
|
| 2011 |
Breitner JC, Baker LD, Montine TJ, Meinert CL, Lyketsos CG, Ashe KH, Brandt J, Craft S, Evans DE, Green RC, Ismail MS, Martin BK, Mullan MJ, Sabbagh M, Tariot PN, et al. Extended results of the Alzheimer's disease anti-inflammatory prevention trial. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 402-11. PMID 21784351 DOI: 10.1016/J.Jalz.2010.12.014 |
0.304 |
|
| 2011 |
Paris D, Mathura V, Ait-Ghezala G, Beaulieu-Abdelahad D, Patel N, Bachmeier C, Mullan M. Flavonoids lower Alzheimer's Aβ production via an NFκB dependent mechanism. Bioinformation. 6: 229-36. PMID 21738321 DOI: 10.6026/97320630006229 |
0.352 |
|
| 2011 |
Luis CA, Abdullah L, Ait-Ghezala G, Mouzon B, Keegan AP, Crawford F, Mullan M. Feasibility of Predicting MCI/AD Using Neuropsychological Tests and Serum β-Amyloid. International Journal of Alzheimer's Disease. 2011: 786264. PMID 21660215 DOI: 10.4061/2011/786264 |
0.521 |
|
| 2011 |
Bachmeier C, Beaulieu-Abdelahad D, Mullan M, Paris D. Selective dihydropyiridine compounds facilitate the clearance of β-amyloid across the blood-brain barrier. European Journal of Pharmacology. 659: 124-9. PMID 21497592 DOI: 10.1016/J.Ejphar.2011.03.048 |
0.374 |
|
| 2011 |
Paris D, Bachmeier C, Patel N, Quadros A, Volmar CH, Laporte V, Ganey J, Beaulieu-Abdelahad D, Ait-Ghezala G, Crawford F, Mullan MJ. Selective antihypertensive dihydropyridines lower Aβ accumulation by targeting both the production and the clearance of Aβ across the blood-brain barrier. Molecular Medicine (Cambridge, Mass.). 17: 149-62. PMID 21170472 DOI: 10.2119/Molmed.2010.00180 |
0.735 |
|
| 2011 |
Bakshi P, Margenthaler E, Reed J, Crawford F, Mullan M. Depletion of CXCR2 inhibits γ-secretase activity and amyloid-β production in a murine model of Alzheimer's disease. Cytokine. 53: 163-9. PMID 21084199 DOI: 10.1016/J.Cyto.2010.10.008 |
0.614 |
|
| 2011 |
Mullan M, Bachmeier C, Ait-Ghezala G, Beaulieu-Abdelahad D, Crawford F, Abdullah L, Kenny RA, Kennelly S, Lawlor B, Paris D. Mechanism of action of new Alzheimer's therapeutic in phase III clinical trials Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.09.124 |
0.474 |
|
| 2011 |
Lawlor B, Crawford F, Rikkert MO, Mullan M, Tsolaki M, Borjesson A, Pasquier F, Riepe M, Kenny RA, Howard R, Gaynor S, Molloy W. NILVAD: An investigator initiated multi-centre placebo-controlled phase III trial of Nilvadipine, a calcium channel blocker, in mild-to-moderate Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.09.120 |
0.478 |
|
| 2011 |
Luis C, Abdullah L, Ait-Ghezala G, Keegan A, Ferguson S, Crawford F, Mullan M. A novel screening approach for MCI/AD Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.722 |
0.504 |
|
| 2011 |
Crawford F, Crynen G, Reed J, Katz B, Ducatenzeiler A, Mullan M, Cuello C. Proteomic characterization of a novel rat model of Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.1447 |
0.521 |
|
| 2010 |
Bachmeier C, Mullan M, Paris D. Characterization and use of human brain microvascular endothelial cells to examine β-amyloid exchange in the blood-brain barrier. Cytotechnology. 62: 519-29. PMID 20954006 DOI: 10.1007/S10616-010-9313-X |
0.336 |
|
| 2010 |
Paris D, Ganey N, Banasiak M, Laporte V, Patel N, Mullan M, Murphy SF, Yee GT, Bachmeier C, Ganey C, Beaulieu-Abdelahad D, Mathura VS, Brem S, Mullan M. Impaired orthotopic glioma growth and vascularization in transgenic mouse models of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 11251-8. PMID 20739545 DOI: 10.1523/Jneurosci.2586-10.2010 |
0.463 |
|
| 2010 |
Paris D, Ganey NJ, Laporte V, Patel NS, Beaulieu-Abdelahad D, Bachmeier C, March A, Ait-Ghezala G, Mullan MJ. Reduction of beta-amyloid pathology by celastrol in a transgenic mouse model of Alzheimer's disease. Journal of Neuroinflammation. 7: 17. PMID 20211007 DOI: 10.1186/1742-2094-7-17 |
0.334 |
|
| 2010 |
Ferguson S, Mouzon B, Kayihan G, Wood M, Poon F, Doore S, Mathura V, Humphrey J, O'Steen B, Hayes R, Roses A, Mullan M, Crawford F. Apolipoprotein E genotype and oxidative stress response to traumatic brain injury. Neuroscience. 168: 811-9. PMID 20105454 DOI: 10.1016/J.Neuroscience.2010.01.031 |
0.483 |
|
| 2010 |
Patel NS, Mathura VS, Bachmeier C, Beaulieu-Abdelahad D, Laporte V, Weeks O, Mullan M, Paris D. Alzheimer's beta-amyloid peptide blocks vascular endothelial growth factor mediated signaling via direct interaction with VEGFR-2. Journal of Neurochemistry. 112: 66-76. PMID 19818105 DOI: 10.1111/J.1471-4159.2009.06426.X |
0.758 |
|
| 2010 |
Kayihan GC, Wood M, Mouzon B, Ferguson S, Margenthaler E, Mathura V, Mullan M, Crawford F. Gulf War agents trigger discrete transcriptional changes in human neuronal cells Toxicological and Environmental Chemistry. 92: 1783-1799. DOI: 10.1080/02772241003611946 |
0.377 |
|
| 2009 |
Bakshi P, Jin C, Broutin P, Berhane B, Reed J, Mullan M. Structural optimization of a CXCR2-directed antagonist that indirectly inhibits gamma-secretase and reduces Abeta. Bioorganic & Medicinal Chemistry. 17: 8102-12. PMID 19853461 DOI: 10.1016/J.Bmc.2009.09.051 |
0.403 |
|
| 2009 |
Abdullah L, Luis C, Paris D, Mouzon B, Ait-Ghezala G, Keegan AP, Wang D, Crawford F, Mullan M. Serum Abeta levels as predictors of conversion to mild cognitive impairment/Alzheimer disease in an ADAPT subcohort. Molecular Medicine (Cambridge, Mass.). 15: 432-7. PMID 19707525 DOI: 10.2119/Molmed.2009.00083 |
0.586 |
|
| 2009 |
Volmar CH, Ait-Ghezala G, Frieling J, Weeks OI, Mullan MJ. CD40/CD40L interaction induces Abeta production and increases gamma-secretase activity independently of tumor necrosis factor receptor associated factor (TRAF) signaling. Experimental Cell Research. 315: 2265-74. PMID 19422822 DOI: 10.1016/J.Yexcr.2009.04.023 |
0.806 |
|
| 2009 |
Crawford F, Wood M, Ferguson S, Mathura V, Gupta P, Humphrey J, Mouzon B, Laporte V, Margenthaler E, O'Steen B, Hayes R, Roses A, Mullan M. Apolipoprotein E-genotype dependent hippocampal and cortical responses to traumatic brain injury. Neuroscience. 159: 1349-62. PMID 19409232 DOI: 10.1016/J.Neuroscience.2009.01.033 |
0.523 |
|
| 2009 |
Abdullah L, Luis C, Paris D, Ait-ghezala G, Mouzon B, Allen E, Parrish J, Mullan MA, Ferguson S, Wood M, Crawford F, Mullan M. High serum Abeta and vascular risk factors in first-degree relatives of Alzheimer's disease patients. Molecular Medicine (Cambridge, Mass.). 15: 95-100. PMID 19081767 DOI: 10.2119/Molmed.2008.00118 |
0.59 |
|
| 2009 |
Luis CA, Abdullah L, Paris D, Quadros A, Mullan M, Mouzon B, Ait-Ghezala G, Crawford F, Mullan M. Serum beta-amyloid correlates with neuropsychological impairment. Neuropsychology, Development, and Cognition. Section B, Aging, Neuropsychology and Cognition. 16: 203-18. PMID 18923961 DOI: 10.1080/13825580802411766 |
0.561 |
|
| 2009 |
Abdullah L, Reed J, Kayihan G, Mathura V, Mouzon B, Mullan M, Crawford F. Proteomic analysis of human neuronal cells treated with the gulf war agent pyridostigmine bromide Journal of Proteomics and Bioinformatics. 2: 439-444. DOI: 10.4172/Jpb.1000103 |
0.45 |
|
| 2008 |
Bakshi P, Margenthaler E, Laporte V, Crawford F, Mullan M. Novel role of CXCR2 in regulation of gamma-secretase activity. Acs Chemical Biology. 3: 777-89. PMID 19067586 DOI: 10.1021/Cb800167A |
0.564 |
|
| 2008 |
Ait-ghezala G, Abdullah L, Volmar CH, Paris D, Luis CA, Quadros A, Mouzon B, Mullan MA, Keegan AP, Parrish J, Crawford FC, Mathura VS, Mullan MJ. Diagnostic utility of APOE, soluble CD40, CD40L, and Abeta1-40 levels in plasma in Alzheimer's disease. Cytokine. 44: 283-7. PMID 18835787 DOI: 10.1016/J.Cyto.2008.08.013 |
0.759 |
|
| 2008 |
Laporte V, Ait-Ghezala G, Volmar CH, Ganey C, Ganey N, Wood M, Mullan M. CD40 ligation mediates plaque-associated tau phosphorylation in beta-amyloid overproducing mice. Brain Research. 1231: 132-42. PMID 18606155 DOI: 10.1016/J.Brainres.2008.06.032 |
0.719 |
|
| 2008 |
Martin BK, Szekely C, Brandt J, Piantadosi S, Breitner JC, Craft S, Evans D, Green R, Mullan M. Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib. Archives of Neurology. 65: 896-905. PMID 18474729 DOI: 10.1001/Archneur.2008.65.7.Nct70006 |
0.303 |
|
| 2008 |
Volmar CH, Ait-Ghezala G, Frieling J, Paris D, Mullan MJ. The granulocyte macrophage colony stimulating factor (GM-CSF) regulates amyloid beta (Abeta) production. Cytokine. 42: 336-44. PMID 18434187 DOI: 10.1016/J.Cyto.2008.03.007 |
0.694 |
|
| 2008 |
Patel NS, Quadros A, Brem S, Wotoczek-Obadia M, Mathura VS, Laporte V, Mullan M, Paris D. Potent anti-angiogenic motifs within the Alzheimer beta-amyloid peptide. Amyloid : the International Journal of Experimental and Clinical Investigation : the Official Journal of the International Society of Amyloidosis. 15: 5-19. PMID 18266117 DOI: 10.1080/13506120701814723 |
0.342 |
|
| 2007 |
Poon HF, Abdullah L, Reed J, Doore SM, Laird C, Mathura V, Mullan M, Crawford F. Improving image analysis in 2DGE-based redox proteomics by labeling protein carbonyl with fluorescent hydroxylamine. Biological Procedures Online. 9: 65-72. PMID 18385803 DOI: 10.1251/Bpo134 |
0.435 |
|
| 2007 |
Abdullah L, Paris D, Luis C, Quadros A, Parrish J, Valdes L, Keegan AP, Mathura V, Crawford F, Mullan M. The influence of diagnosis, intra- and inter-person variability on serum and plasma Abeta levels. Neuroscience Letters. 428: 53-8. PMID 17964720 DOI: 10.1016/J.Neulet.2007.09.058 |
0.561 |
|
| 2007 |
Crawford FC, Wood M, Ferguson S, Mathura VS, Faza B, Wilson S, Fan T, O'Steen B, Ait-Ghezala G, Hayes R, Mullan MJ. Genomic analysis of response to traumatic brain injury in a mouse model of Alzheimer's disease (APPsw). Brain Research. 1185: 45-58. PMID 17961517 DOI: 10.1016/j.brainres.2007.09.042 |
0.497 |
|
| 2007 |
Ait-Ghezala G, Volmar CH, Frieling J, Paris D, Tweed M, Bakshi P, Mullan M. CD40 promotion of amyloid beta production occurs via the NF-kappaB pathway. The European Journal of Neuroscience. 25: 1685-95. PMID 17432959 DOI: 10.1111/J.1460-9568.2007.05424.X |
0.691 |
|
| 2007 |
Paris D, Patel N, Quadros A, Linan M, Bakshi P, Ait-Ghezala G, Mullan M. Inhibition of Abeta production by NF-kappaB inhibitors. Neuroscience Letters. 415: 11-6. PMID 17223266 DOI: 10.1016/J.Neulet.2006.12.029 |
0.4 |
|
| 2007 |
Crowell TA, Luis CA, Cox DE, Mullan M. Neuropsychological comparison of Alzheimer's disease and dementia with lewy bodies. Dementia and Geriatric Cognitive Disorders. 23: 120-5. PMID 17148939 DOI: 10.1159/000097791 |
0.327 |
|
| 2007 |
Poon HF, Abdullah L, Mullan MA, Mullan MJ, Crawford FC. Cocaine-induced oxidative stress precedes cell death in human neuronal progenitor cells. Neurochemistry International. 50: 69-73. PMID 16956698 DOI: 10.1016/j.neuint.2006.06.012 |
0.334 |
|
| 2007 |
Volmar CH, Patel N, Quadros AN, Paris D, Mathura VS, Mullan M. Introduction to biological systems Bioinformatics: a Concept-Based Introduction. 1-11. DOI: 10.1007/978-0-387-84870-9_1 |
0.558 |
|
| 2006 |
Borenstein AR, Mortimer JA, Wu Y, Jureidini-Webb FM, Fallin MD, Small BJ, Mullan M, Crawford FC. Apolipoprotein E and cognition in community-based samples of African Americans and Caucasians. Ethnicity & Disease. 16: 9-15. PMID 16599342 |
0.382 |
|
| 2006 |
Crawford FC, Wood ML, Wilson SE, Mathura VS, Hollen TR, Geall F, Kolippakkam DN, Mullan MJ. Cocaine induced inflammatory response in human neuronal progenitor cells. Journal of Neurochemistry. 97: 662-74. PMID 16539665 DOI: 10.1111/j.1471-4159.2006.03760.x |
0.369 |
|
| 2006 |
Laporte V, Ait-Ghezala G, Volmar CH, Mullan M. CD40 deficiency mitigates Alzheimer's disease pathology in transgenic mouse models. Journal of Neuroinflammation. 3: 3. PMID 16504112 DOI: 10.1186/1742-2094-3-3 |
0.717 |
|
| 2006 |
Crowell TA, Paramadevan J, Abdullah L, Mullan M. Beneficial effect of cholinesterase inhibitor medications on recognition memory performance in mild to moderate Alzheimer's disease: preliminary findings. Journal of Geriatric Psychiatry and Neurology. 19: 13-5. PMID 16449754 DOI: 10.1177/0891988705284711 |
0.361 |
|
| 2006 |
Abdullah L, Ait-Ghezala G, Crawford F, Crowell TA, Barker WW, Duara R, Mullan M. The cyclooxygenase 2 -765 C promoter allele is a protective factor for Alzheimer's disease. Neuroscience Letters. 395: 240-3. PMID 16309832 DOI: 10.1016/J.Neulet.2005.10.090 |
0.556 |
|
| 2005 |
Town T, Tan J, Flavell RA, Mullan M. T-cells in Alzheimer's disease. Neuromolecular Medicine. 7: 255-64. PMID 16247185 DOI: 10.1385/Nmm:7:3:255 |
0.693 |
|
| 2005 |
Ait-Ghezala G, Mathura VS, Laporte V, Quadros A, Paris D, Patel N, Volmar CH, Kolippakkam D, Crawford F, Mullan M. Genomic regulation after CD40 stimulation in microglia: relevance to Alzheimer's disease. Brain Research. Molecular Brain Research. 140: 73-85. PMID 16182406 DOI: 10.1016/J.Molbrainres.2005.07.014 |
0.773 |
|
| 2005 |
Mathura VS, Paris D, Ait-Ghezala G, Quadros A, Patel NS, Kolippakkam DN, Volmar CH, Mullan MJ. Model of Alzheimer's disease amyloid-beta peptide based on a RNA binding protein. Biochemical and Biophysical Research Communications. 332: 585-92. PMID 15896718 DOI: 10.1016/J.Bbrc.2005.04.164 |
0.652 |
|
| 2005 |
Paris D, Ait-Ghezala G, Mathura VS, Patel N, Quadros A, Laporte V, Mullan M. Anti-angiogenic activity of the mutant Dutch A(beta) peptide on human brain microvascular endothelial cells. Brain Research. Molecular Brain Research. 136: 212-30. PMID 15893605 DOI: 10.1016/J.Molbrainres.2005.02.011 |
0.362 |
|
| 2005 |
Paris D, Quadros A, Patel N, DelleDonne A, Humphrey J, Mullan M. Inhibition of angiogenesis and tumor growth by beta and gamma-secretase inhibitors. European Journal of Pharmacology. 514: 1-15. PMID 15878319 DOI: 10.1016/J.Ejphar.2005.02.050 |
0.343 |
|
| 2005 |
Patel NS, Paris D, Mathura V, Quadros AN, Crawford FC, Mullan MJ. Inflammatory cytokine levels correlate with amyloid load in transgenic mouse models of Alzheimer's disease. Journal of Neuroinflammation. 2: 9. PMID 15762998 DOI: 10.1186/1742-2094-2-9 |
0.467 |
|
| 2004 |
Harwood DG, Barker WW, Ownby RL, St George-Hyslop P, Mullan M, Duara R. Apolipoprotein E polymorphism and age of onset for Alzheimer's disease in a bi-ethnic sample. International Psychogeriatrics / Ipa. 16: 317-26. PMID 15559755 DOI: 10.1017/S104161020400033X |
0.38 |
|
| 2004 |
Paris D, Townsend K, Quadros A, Humphrey J, Sun J, Brem S, Wotoczek-Obadia M, DelleDonne A, Patel N, Obregon DF, Crescentini R, Abdullah L, Coppola D, Rojiani AM, Crawford F, ... ... Mullan M, et al. Inhibition of angiogenesis by Abeta peptides. Angiogenesis. 7: 75-85. PMID 15302999 DOI: 10.1023/B:Agen.0000037335.17717.Bf |
0.518 |
|
| 2004 |
Paris D, Patel N, DelleDonne A, Quadros A, Smeed R, Mullan M. Impaired angiogenesis in a transgenic mouse model of cerebral amyloidosis. Neuroscience Letters. 366: 80-5. PMID 15265595 DOI: 10.1016/J.Neulet.2004.05.017 |
0.428 |
|
| 2004 |
Todd Roach J, Volmar CH, Dwivedi S, Town T, Crescentini R, Crawford F, Tan J, Mullan M. Behavioral effects of CD40-CD40L pathway disruption in aged PSAPP mice. Brain Research. 1015: 161-8. PMID 15223380 DOI: 10.1016/J.Brainres.2004.05.004 |
0.796 |
|
| 2004 |
Mott RT, Ait-Ghezala G, Town T, Mori T, Vendrame M, Zeng J, Ehrhart J, Mullan M, Tan J. Neuronal expression of CD22: novel mechanism for inhibiting microglial proinflammatory cytokine production. Glia. 46: 369-79. PMID 15095367 DOI: 10.1002/Glia.20009 |
0.558 |
|
| 2004 |
Paris D, Quadros A, Humphrey J, Patel N, Crescentini R, Crawford F, Mullan M. Nilvadipine antagonizes both Abeta vasoactivity in isolated arteries, and the reduced cerebral blood flow in APPsw transgenic mice. Brain Research. 999: 53-61. PMID 14746921 DOI: 10.1016/J.Brainres.2003.11.061 |
0.554 |
|
| 2003 |
Quadros A, Patel N, Crescentini R, Crawford F, Paris D, Mullan M. Increased TNFalpha production and Cox-2 activity in organotypic brain slice cultures from APPsw transgenic mice. Neuroscience Letters. 353: 66-8. PMID 14642439 DOI: 10.1016/J.Neulet.2003.08.076 |
0.559 |
|
| 2003 |
Paris D, Humphrey J, Quadros A, Patel N, Crescentini R, Crawford F, Mullan M. Vasoactive effects of A beta in isolated human cerebrovessels and in a transgenic mouse model of Alzheimer's disease: role of inflammation. Neurological Research. 25: 642-51. PMID 14503019 DOI: 10.1179/016164103101201940 |
0.587 |
|
| 2003 |
Crawford FC, Ait-Ghezala G, Morris M, Sutcliffe MJ, Hauser RA, Silver AA, Mullan MJ. Translocation breakpoint in two unrelated Tourette syndrome cases, within a region previously linked to the disorder. Human Genetics. 113: 154-61. PMID 12698358 DOI: 10.1007/s00439-003-0942-4 |
0.375 |
|
| 2003 |
Quadros A, Patel N, Crescentini R, Crawford F, Paris D, Mullan M. Increased TNFα production and Cox-2 activity in organotypic brain slice cultures from APPsw transgenic mice Neuroscience Letters. 353: 66-68. DOI: 10.1016/j.neulet.2003.08.076 |
0.408 |
|
| 2002 |
Townsend KP, Obregon D, Quadros A, Patel N, Volmar Ch, Paris D, Mullan M. Proinflammatory and vasoactive effects of Abeta in the cerebrovasculature. Annals of the New York Academy of Sciences. 977: 65-76. PMID 12480734 DOI: 10.1111/J.1749-6632.2002.Tb04799.X |
0.447 |
|
| 2002 |
Paris D, Townsend KP, Obregon DF, Humphrey J, Mullan M. Pro-inflammatory effect of freshly solubilized beta-amyloid peptides in the brain. Prostaglandins & Other Lipid Mediators. 70: 1-12. PMID 12428674 DOI: 10.1016/S0090-6980(02)00111-9 |
0.382 |
|
| 2002 |
Yuspeh RL, Vanderploeg RD, Crowell TA, Mullan M. Differences in executive functioning between Alzheimer's disease and subcortical ischemic vascular dementia. Journal of Clinical and Experimental Neuropsychology. 24: 745-54. PMID 12424649 DOI: 10.1076/Jcen.24.6.745.8399 |
0.364 |
|
| 2002 |
Tan J, Town T, Abdullah L, Wu Y, Placzek A, Small B, Kroeger J, Crawford F, Richards D, Mullan M. CD45 isoform alteration in CD4+ T cells as a potential diagnostic marker of Alzheimer's disease. Journal of Neuroimmunology. 132: 164-72. PMID 12417447 DOI: 10.1016/S0165-5728(02)00309-0 |
0.689 |
|
| 2002 |
Town T, Vendrame M, Patel A, Poetter D, DelleDonne A, Mori T, Smeed R, Crawford F, Klein T, Tan J, Mullan M. Reduced Th1 and enhanced Th2 immunity after immunization with Alzheimer's beta-amyloid(1-42). Journal of Neuroimmunology. 132: 49-59. PMID 12417433 DOI: 10.1016/S0165-5728(02)00307-7 |
0.676 |
|
| 2002 |
Tan J, Town T, Crawford F, Mori T, DelleDonne A, Crescentini R, Obregon D, Flavell RA, Mullan MJ. Role of CD40 ligand in amyloidosis in transgenic Alzheimer's mice. Nature Neuroscience. 5: 1288-93. PMID 12402041 DOI: 10.1038/Nn968 |
0.739 |
|
| 2002 |
Tan J, Town T, Mullan M. CD40-CD40L interaction in Alzheimer's disease. Current Opinion in Pharmacology. 2: 445-51. PMID 12127879 DOI: 10.1016/S1471-4892(02)00180-7 |
0.659 |
|
| 2002 |
Town T, Zolton J, Shaffner R, Schnell B, Crescentini R, Wu Y, Zeng J, DelleDonne A, Obregon D, Tan J, Mullan M. p35/Cdk5 pathway mediates soluble amyloid-beta peptide-induced tau phosphorylation in vitro. Journal of Neuroscience Research. 69: 362-72. PMID 12125077 DOI: 10.1002/Jnr.10299 |
0.634 |
|
| 2002 |
Ait-Ghezala G, Abdullah L, Crescentini R, Crawford F, Town T, Singh S, Richards D, Duara R, Mullan M. Confirmation of association between D10S583 and Alzheimer's disease in a case--control sample. Neuroscience Letters. 325: 87-90. PMID 12044628 DOI: 10.1016/S0304-3940(02)00243-4 |
0.696 |
|
| 2002 |
Crawford FC, Vanderploeg RD, Freeman MJ, Singh S, Waisman M, Michaels L, Abdullah L, Warden D, Lipsky R, Salazar A, Mullan MJ. APOE genotype influences acquisition and recall following traumatic brain injury. Neurology. 58: 1115-8. PMID 11940706 |
0.405 |
|
| 2002 |
Paris D, Townsend KP, Humphrey J, Obregon DF, Yokota K, Mullan M. Statins inhibit A beta-neurotoxicity in vitro and A beta-induced vasoconstriction and inflammation in rat aortae. Atherosclerosis. 161: 293-9. PMID 11888511 DOI: 10.1016/S0021-9150(01)00660-8 |
0.32 |
|
| 2002 |
Harwood DG, Barker WW, Ownby RL, Mullan M, Duara R. Apolipoprotein E polymorphism and cognitive impairment in a bi-ethnic community-dwelling elderly sample. Alzheimer Disease and Associated Disorders. 16: 8-14. PMID 11882744 DOI: 10.1097/00002093-200201000-00002 |
0.302 |
|
| 2002 |
Tan J, Town T, Mori T, Obregon D, Wu Y, DelleDonne A, Rojiani A, Crawford F, Flavell RA, Mullan M. CD40 is expressed and functional on neuronal cells. The Embo Journal. 21: 643-52. PMID 11847112 DOI: 10.1093/Emboj/21.4.643 |
0.672 |
|
| 2002 |
Schinka JA, Town T, Abdullah L, Crawford FC, Ordorica PI, Francis E, Hughes P, Graves AB, Mortimer JA, Mullan M. A functional polymorphism within the mu-opioid receptor gene and risk for abuse of alcohol and other substances. Molecular Psychiatry. 7: 224-8. PMID 11840318 DOI: 10.1038/Sj.Mp.4000951 |
0.617 |
|
| 2002 |
Crowell TA, Luis CA, Vanderploeg RD, Schinka JA, Mullan M. Memory patterns and executive functioning in Mild Cognitive Impairment and Alzheimer's Disease Aging, Neuropsychology, and Cognition. 9: 288-297. DOI: 10.1076/Anec.9.4.288.8772 |
0.334 |
|
| 2001 |
Russ C, Powell JF, Zhao J, Baker M, Hutton M, Crawford F, Mullan M, Roks G, Cruts M, Lovestone S. The microtubule associated protein Tau gene and Alzheimer's disease--an association study and meta-analysis. Neuroscience Letters. 314: 92-6. PMID 11698154 DOI: 10.1016/S0304-3940(01)02289-3 |
0.635 |
|
| 2001 |
Town T, Tan J, Mullan M. CD40 signaling and Alzheimer's disease pathogenesis. Neurochemistry International. 39: 371-80. PMID 11578772 DOI: 10.1016/S0197-0186(01)00044-4 |
0.607 |
|
| 2001 |
Mori T, Paris D, Town T, Rojiani AM, Sparks DL, Delledonne A, Crawford F, Abdullah LI, Humphrey JA, Dickson DW, Mullan MJ. Cholesterol accumulates in senile plaques of Alzheimer disease patients and in transgenic APP(SW) mice. Journal of Neuropathology and Experimental Neurology. 60: 778-85. PMID 11487052 DOI: 10.1093/Jnen/60.8.778 |
0.685 |
|
| 2001 |
Town T, Tan J, Sansone N, Obregon D, Klein T, Mullan M. Characterization of murine immunoglobulin G antibodies against human amyloid-beta1-42. Neuroscience Letters. 307: 101-4. PMID 11427310 DOI: 10.1016/S0304-3940(01)01951-6 |
0.616 |
|
| 2001 |
Crawford FC, Freeman MJ, Schinka JA, Morris MD, Abdullah LI, Richards D, Sevush S, Duara R, Mullan MJ. Association between Alzheimer's disease and a functional polymorphism in the Myeloperoxidase gene. Experimental Neurology. 167: 456-9. PMID 11161635 DOI: 10.1006/exnr.2000.7560 |
0.505 |
|
| 2000 |
Town T, Schinka J, Tan J, Mullan M. The opioid receptor system and alcoholism: a genetic perspective. European Journal of Pharmacology. 410: 243-248. PMID 11134673 DOI: 10.1016/S0014-2999(00)00818-9 |
0.516 |
|
| 2000 |
Tan J, Town T, Mori T, Wu Y, Saxe M, Crawford F, Mullan M. CD45 opposes beta-amyloid peptide-induced microglial activation via inhibition of p44/42 mitogen-activated protein kinase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 7587-94. PMID 11027218 DOI: 10.1523/Jneurosci.20-20-07587.2000 |
0.704 |
|
| 2000 |
Crawford FC, Freeman MJ, Schinka JA, Abdullah LI, Gold M, Hartman R, Krivian K, Morris MD, Richards D, Duara R, Anand R, Mullan MJ. A polymorphism in the cystatin C gene is a novel risk factor for late-onset Alzheimer's disease. Neurology. 55: 763-8. PMID 10993992 |
0.472 |
|
| 2000 |
Tan J, Town T, Mullan M. CD45 inhibits CD40L-induced microglial activation via negative regulation of the Src/p44/42 MAPK pathway. The Journal of Biological Chemistry. 275: 37224-31. PMID 10978311 DOI: 10.1074/Jbc.M002006200 |
0.556 |
|
| 2000 |
Tandon A, Rogaeva E, Mullan M, St George-Hyslop PH. Molecular genetics of Alzheimer's disease: the role of beta-amyloid and the presenilins. Current Opinion in Neurology. 13: 377-84. PMID 10970053 DOI: 10.1097/00019052-200008000-00003 |
0.304 |
|
| 2000 |
Kuo YM, Crawford F, Mullan M, Kokjohn TA, Emmerling MR, Weller RO, Roher AE. Elevated A beta and apolipoprotein E in A betaPP transgenic mice and its relationship to amyloid accumulation in Alzheimer's disease. Molecular Medicine (Cambridge, Mass.). 6: 430-9. PMID 10952022 DOI: 10.1007/Bf03401785 |
0.556 |
|
| 2000 |
Paris D, Town T, Humphrey J, Yokota K, Mullan M. Cholesterol modulates vascular reactivity to endothelin-1 by stimulating a pro-inflammatory pathway. Biochemical and Biophysical Research Communications. 274: 553-8. PMID 10913376 DOI: 10.1006/Bbrc.2000.3174 |
0.537 |
|
| 2000 |
Sevush S, Peruyera G, Crawford F, Mullan M. Apolipoprotein-E epsilon 4 allele frequency and conferred risk for Cuban Americans with Alzheimer's disease. The American Journal of Geriatric Psychiatry : Official Journal of the American Association For Geriatric Psychiatry. 8: 254-6. PMID 10910426 DOI: 10.1097/00019442-200008000-00013 |
0.474 |
|
| 2000 |
Crawford FC, Freeman MJ, Schinka J, Abdullah LI, Richards D, Sevush S, Duara R, Mullan MJ. The genetic association between Cathepsin D and Alzheimer's disease. Neuroscience Letters. 289: 61-5. PMID 10899409 DOI: 10.1016/S0304-3940(00)01260-X |
0.513 |
|
| 2000 |
Paris D, Town T, Mori T, Parker TA, Humphrey J, Mullan M. Soluble beta-amyloid peptides mediate vasoactivity via activation of a pro-inflammatory pathway. Neurobiology of Aging. 21: 183-97. PMID 10867203 DOI: 10.1016/S0197-4580(99)00111-6 |
0.603 |
|
| 2000 |
Small BJ, Graves AB, McEvoy CL, Crawford FC, Mullan M, Mortimer JA. Is APOE--epsilon4 a risk factor for cognitive impairment in normal aging? Neurology. 54: 2082-8. PMID 10851367 DOI: 10.1212/WNL.54.11.2082 |
0.397 |
|
| 2000 |
Paris D, Town T, Parker T, Humphrey J, Mullan M. beta-Amyloid vasoactivity and proinflammation in microglia can be blocked by cGMP-elevating agents. Annals of the New York Academy of Sciences. 903: 446-50. PMID 10818536 DOI: 10.1111/J.1749-6632.2000.Tb06397.X |
0.587 |
|
| 2000 |
Suo Z, Su G, Placzek A, Kundtz A, Humphrey J, Crawford F, Mullan M. A beta vasoactivity in vivo. Annals of the New York Academy of Sciences. 903: 156-63. PMID 10818502 DOI: 10.1111/J.1749-6632.2000.Tb06363.X |
0.523 |
|
| 2000 |
Paris D, Town T, Parker T, Humphrey J, Mullan M. A beta vasoactivity: an inflammatory reaction. Annals of the New York Academy of Sciences. 903: 97-109. PMID 10818494 DOI: 10.1111/J.1749-6632.2000.Tb06355.X |
0.587 |
|
| 2000 |
Crawford F, Freeman M, Abdullah L, Schinka J, Gold M, Duara R, Mullan M. No association between the NOS3 codon 298 polymorphism and Alzheimer's disease in a sample from the United States. Annals of Neurology. 47: 687. PMID 10805350 DOI: 10.1002/1531-8249(200005)47:5<687::Aid-Ana30>3.0.Co;2-4 |
0.51 |
|
| 2000 |
Crawford F, Abdullah L, Schinka J, Suo Z, Gold M, Duara R, Mullan M. Gender-specific association of the angiotensin converting enzyme gene with Alzheimer's disease. Neuroscience Letters. 280: 215-9. PMID 10675799 DOI: 10.1016/S0304-3940(00)00791-6 |
0.565 |
|
| 2000 |
Paris D, Town T, Mullan M. Novel strategies for opposing murine microglial activation. Neuroscience Letters. 278: 5-8. PMID 10643787 DOI: 10.1016/S0304-3940(99)00901-5 |
0.542 |
|
| 2000 |
Morris M, Crawford F, Freeman MJ, Schinka J, Gold M, Duara R, Mullan M. Age and gender-specific effects of a myeloperoxidase promoter polymorphism in Alzheimer's disease Neurobiology of Aging. 21: 249. DOI: 10.1016/S0197-4580(00)83457-0 |
0.531 |
|
| 2000 |
Small BJ, Abdullah L, Freeman MJ, Crawford F, Duara R, Mullan M. Age and gender as risk modifiers of ApoE-ϵ4 in Alzheimer's disease Neurobiology of Aging. 21: 247. DOI: 10.1016/S0197-4580(00)83448-X |
0.535 |
|
| 2000 |
Crawford F, Freeman MJ, Schinka J, Abdullah L, Gold M, Duara R, Mullan M. The cystatin C gene as a novel genetic risk factor for late onset Alzheimer's disease Neurobiology of Aging. 21: 204. DOI: 10.1016/S0197-4580(00)83247-9 |
0.515 |
|
| 2000 |
Mori T, Paris D, Crawford F, Mullan M. Histochemical detection of cholesterol in the senile plaques of transgenic APPSW mice Neurobiology of Aging. 21: 119. DOI: 10.1016/S0197-4580(00)82336-2 |
0.485 |
|
| 2000 |
Tan J, Town T, Paris D, Mori T, Crawford F, Mullan M. The CD40-CD40L interaction leads to microglial activation following β-amyloid stimulation Neurobiology of Aging. 21: 188. DOI: 10.1016/S0197-4580(00)82186-7 |
0.642 |
|
| 2000 |
Townsend K, Paris D, Town T, Humphrey J, Yokota K, Mullan M. Cholesterol as well as Aβ induces vasoconstruction by stimulating a similar pro-inflammatory pathway Neurobiology of Aging. 21: 180. DOI: 10.1016/S0197-4580(00)82149-1 |
0.561 |
|
| 2000 |
Town T, Tan J, Paris D, Wu Y, Mullan M. Ligation of microglial CD40 results in SRC kinase-induced P44/42 mapk-dependent TNFα-production Neurobiology of Aging. 21: 180. DOI: 10.1016/S0197-4580(00)82146-6 |
0.532 |
|
| 1999 |
Tan J, Town T, Paris D, Mori T, Suo Z, Crawford F, Mattson MP, Flavell RA, Mullan M. Microglial activation resulting from CD40-CD40L interaction after beta-amyloid stimulation. Science (New York, N.Y.). 286: 2352-5. PMID 10600748 DOI: 10.1126/Science.286.5448.2352 |
0.743 |
|
| 1999 |
Tan J, Town T, Saxe M, Paris D, Wu Y, Mullan M. Ligation of microglial CD40 results in p44/42 mitogen-activated protein kinase-dependent TNF-alpha production that is opposed by TGF-beta 1 and IL-10. Journal of Immunology (Baltimore, Md. : 1950). 163: 6614-21. PMID 10586056 |
0.513 |
|
| 1999 |
Tan J, Town T, Suo Z, Wu Y, Song S, Kundtz A, Kroeger J, Humphrey J, Crawford F, Mullan M. Induction of CD40 on human endothelial cells by Alzheimer's beta-amyloid peptides. Brain Research Bulletin. 50: 143-8. PMID 10535333 DOI: 10.1016/S0361-9230(99)00122-7 |
0.674 |
|
| 1999 |
King DL, Arendash GW, Crawford F, Sterk T, Menendez J, Mullan MJ. Progressive and gender-dependent cognitive impairment in the APP(SW) transgenic mouse model for Alzheimer's disease. Behavioural Brain Research. 103: 145-62. PMID 10513583 DOI: 10.1016/S0166-4328(99)00037-6 |
0.453 |
|
| 1999 |
Tan J, Town T, Placzek A, Kundtz A, Yu H, Mullan M. Bcl-X(L) inhibits apoptosis and necrosis produced by Alzheimer's beta-amyloid1-40 peptide in PC12 cells. Neuroscience Letters. 272: 5-8. PMID 10507529 DOI: 10.1016/S0304-3940(99)00525-X |
0.57 |
|
| 1999 |
Town T, Paris D, Parker TA, Kundtz A, Tan J, Duara R, Gold M, Crawford F, Mullan M. Alzheimers disease is not associated with the hypertension genetic risk factors PLA(2) or G protein beta3, either independently or interactively with apolipoprotein E. American Journal of Medical Genetics. 88: 465-8. PMID 10490699 DOI: 10.1002/(Sici)1096-8628(19991015)88:5<465::Aid-Ajmg5>3.0.Co;2-M |
0.701 |
|
| 1999 |
Town T, Abdullah L, Crawford F, Schinka J, Ordorica PI, Francis E, Hughes P, Duara R, Mullan M. Association of a functional mu-opioid receptor allele (+118A) with alcohol dependency. American Journal of Medical Genetics. 88: 458-61. PMID 10490697 DOI: 10.1002/(Sici)1096-8628(19991015)88:5<458::Aid-Ajmg3>3.0.Co;2-S |
0.61 |
|
| 1999 |
Crawford F, Freeman M, Town T, Fallin D, Gold M, Duara R, Mullan M. No genetic association between polymorphisms in the Tau gene and Alzheimer's disease in clinic or population based samples. Neuroscience Letters. 266: 193-6. PMID 10465706 DOI: 10.1016/S0304-3940(99)00303-1 |
0.71 |
|
| 1999 |
Crawford F, Town T, Freeman M, Schinka J, Gold M, Duara R, Mullan M. The alpha-2 macroglobulin gene is not associated with Alzheimer's disease in a case-control sample. Neuroscience Letters. 270: 133-6. PMID 10462112 DOI: 10.1016/S0304-3940(99)00470-X |
0.689 |
|
| 1999 |
Tan J, Town T, Paris D, Placzek A, Parker T, Crawford F, Yu H, Humphrey J, Mullan M. Activation of microglial cells by the CD40 pathway: relevance to multiple sclerosis. Journal of Neuroimmunology. 97: 77-85. PMID 10408982 DOI: 10.1016/S0165-5728(99)00053-3 |
0.635 |
|
| 1999 |
Arendash GW, Su GC, Crawford FC, Bjugstad KB, Mullan M. Intravascular beta-amyloid infusion increases blood pressure: implications for a vasoactive role of beta-amyloid in the pathogenesis of Alzheimer's disease. Neuroscience Letters. 268: 17-20. PMID 10400067 DOI: 10.1016/S0304-3940(99)00239-6 |
0.533 |
|
| 1999 |
Paris D, Town T, Parker TA, Tan J, Humphrey J, Crawford F, Mullan M. Inhibition of Alzheimer's beta-amyloid induced vasoactivity and proinflammatory response in microglia by a cGMP-dependent mechanism. Experimental Neurology. 157: 211-21. PMID 10222124 DOI: 10.1006/Exnr.1999.7055 |
0.719 |
|
| 1999 |
Harwood DG, Barker WW, Loewenstein DA, Ownby RL, St George-Hyslop P, Mullan M, Duara R. A cross-ethnic analysis of risk factors for AD in white Hispanics and white non-Hispanics. Neurology. 52: 551-6. PMID 10025786 DOI: 10.1212/Wnl.52.3.551 |
0.352 |
|
| 1999 |
Su GC, Arendash GW, Kalaria RN, Bjugstad KB, Mullan M. Intravascular infusions of soluble beta-amyloid compromise the blood-brain barrier, activate CNS glial cells and induce peripheral hemorrhage. Brain Research. 818: 105-17. PMID 9914443 DOI: 10.1016/S0006-8993(98)01143-3 |
0.436 |
|
| 1998 |
Suo Z, Humphrey J, Kundtz A, Sethi F, Placzek A, Crawford F, Mullan M. Soluble Alzheimers beta-amyloid constricts the cerebral vasculature in vivo. Neuroscience Letters. 257: 77-80. PMID 9865931 DOI: 10.1016/S0304-3940(98)00814-3 |
0.576 |
|
| 1998 |
Paris D, Town T, Parker TA, Humphrey J, Mullan M. Isoform-specific vasoconstriction induced by apolipoprotein E and modulation of this effect by Alzheimer's beta-amyloid peptide. Neuroscience Letters. 256: 73-6. PMID 9853706 DOI: 10.1016/S0304-3940(98)00764-2 |
0.658 |
|
| 1998 |
Crawford F, Soto C, Suo Z, Fang C, Parker T, Sawar A, Frangione B, Mullan M. Alzheimer's beta-amyloid vasoactivity: identification of a novel beta-amyloid conformational intermediate. Febs Letters. 436: 445-8. PMID 9801166 DOI: 10.1016/S0014-5793(98)01170-3 |
0.495 |
|
| 1998 |
Suo Z, Tan J, Placzek A, Crawford F, Fang C, Mullan M. Alzheimer's beta-amyloid peptides induce inflammatory cascade in human vascular cells: the roles of cytokines and CD40. Brain Research. 807: 110-7. PMID 9757011 DOI: 10.1016/S0006-8993(98)00780-X |
0.559 |
|
| 1998 |
Town T, Paris D, Fallin D, Duara R, Barker W, Gold M, Crawford F, Mullan M. The -491A/T apolipoprotein E promoter polymorphism association with Alzheimer's disease: independent risk and linkage disequilibrium with the known APOE polymorphism. Neuroscience Letters. 252: 95-8. PMID 9756330 DOI: 10.1016/S0304-3940(98)00567-9 |
0.657 |
|
| 1998 |
Crawford F, Fallin D, Suo Z, Abdullah L, Gold M, Gauntlett A, Duara R, Mullan M. The butyrylcholinesterase gene is neither independently nor synergistically associated with late-onset AD in clinic- and community-based populations. Neuroscience Letters. 249: 115-8. PMID 9682830 DOI: 10.1016/S0304-3940(98)00423-6 |
0.556 |
|
| 1998 |
Paris D, Parker TA, Town T, Suo Z, Fang C, Humphrey J, Crawford F, Mullan M. Role of peroxynitrite in the vasoactive and cytotoxic effects of Alzheimer's beta-amyloid1-40 peptide. Experimental Neurology. 152: 116-22. PMID 9682018 DOI: 10.1006/Exnr.1998.6828 |
0.712 |
|
| 1998 |
Crawford F, Suo Z, Fang C, Mullan M. Characteristics of the in vitro vasoactivity of beta-amyloid peptides. Experimental Neurology. 150: 159-68. PMID 9514824 DOI: 10.1006/Exnr.1997.6743 |
0.499 |
|
| 1997 |
Fallin D, Kundtz A, Town T, Gauntlett AC, Duara R, Barker W, Crawford F, Mullan M. No association between the low density lipoprotein receptor-related protein (LRP) gene and late-onset Alzheimer's disease in a community-based sample. Neuroscience Letters. 233: 145-7. PMID 9350853 DOI: 10.1016/S0304-3940(97)00634-4 |
0.702 |
|
| 1997 |
Crawford F, Suo Z, Fang C, Mullan M. beta-Amyloid peptides and enhancement of vasoconstriction by endothelin-1. Annals of the New York Academy of Sciences. 826: 461-2. PMID 9329724 DOI: 10.1111/J.1749-6632.1997.Tb48504.X |
0.502 |
|
| 1997 |
Crawford F, Suo Z, Fang C, Sawar A, Su G, Arendash G, Mullan M. The vasoactivity of A beta peptides. Annals of the New York Academy of Sciences. 826: 35-46. PMID 9329679 DOI: 10.1111/J.1749-6632.1997.Tb48459.X |
0.49 |
|
| 1997 |
Suo Z, Fang C, Crawford F, Mullan M. Superoxide free radical and intracellular calcium mediate A beta(1-42) induced endothelial toxicity. Brain Research. 762: 144-52. PMID 9262168 DOI: 10.1016/S0006-8993(97)00383-1 |
0.546 |
|
| 1997 |
Town T, Fallin D, Crawford F, Walsh S, Solomon R, Mullan M. Lack of association between the apolipoprotein E epsilon4 allele (APOE epsilon4) and chronic schizophrenia. American Journal of Medical Genetics. 74: 451-2. PMID 9259385 DOI: 10.1002/(Sici)1096-8628(19970725)74:4<451::Aid-Ajmg20>3.0.Co;2-G |
0.613 |
|
| 1997 |
Cai X, Fallin D, Stanton J, Scibelli P, Duara R, Crawford F, Mullan M. APOE is linked to Alzheimer's disease in a large pedigree. American Journal of Medical Genetics. 74: 365-9. PMID 9259370 DOI: 10.1002/(Sici)1096-8628(19970725)74:4<365::Aid-Ajmg5>3.0.Co;2-O |
0.592 |
|
| 1997 |
Fallin D, Gauntlett AC, Scibelli P, Cai X, Duara R, Gold M, Crawford F, Mullan M. No association between the very low density lipoprotein receptor gene and late-onset Alzheimer's disease nor interaction with the apolipoprotein E gene in population-based and clinic samples. Genetic Epidemiology. 14: 299-305. PMID 9181358 DOI: 10.1002/(Sici)1098-2272(1997)14:3<299::Aid-Gepi7>3.0.Co;2-0 |
0.542 |
|
| 1997 |
Cai X, Stanton J, Fallin D, Hoyne J, Duara R, Gold M, Sevush S, Scibelli P, Crawford F, Mullan M. No association between the intronic presenilin-1 polymorphism and Alzheimer's disease in clinic and population-based samples. American Journal of Medical Genetics. 74: 202-3. PMID 9129725 DOI: 10.1002/(Sici)1096-8628(19970418)74:2<202::Aid-Ajmg18>3.0.Co;2-M |
0.56 |
|
| 1997 |
Fallin D, Reading S, Schinka J, Hoyne J, Scibelli P, Gold M, Crawford F, Mullan M. No interaction between the APOE and the alpha-1-antichymotrypsin genes on risk for Alzheimer's disease. American Journal of Medical Genetics. 74: 192-4. PMID 9129722 DOI: 10.1002/(Sici)1096-8628(19970418)74:2<192::Aid-Ajmg15>3.0.Co;2-D |
0.576 |
|
| 1996 |
Mullan M, Scibelli P, Duara R, Fallin D, Gold M, Schinka J, Hoyne J, Osborne A, Sevush S, Crawford F. Familial and population-based studies of apolipoprotein E and Alzheimer's disease. Annals of the New York Academy of Sciences. 802: 16-26. PMID 8993480 DOI: 10.1111/J.1749-6632.1996.Tb32594.X |
0.559 |
|
| 1996 |
Crawford F, Hoyne J, Cai X, Osborne A, Poston D, Zaglul J, Dajani N, Walsh S, Bradley R, Solomon R, Mullan M. Dopamine DRD2/Cys311 is not associated with chronic schizophrenia. American Journal of Medical Genetics. 67: 483-4. PMID 8886166 DOI: 10.1002/(Sici)1096-8628(19960920)67:5<483::Aid-Ajmg8>3.0.Co;2-L |
0.431 |
|
| 1996 |
Thomas T, Thomas G, McLendon C, Sutton T, Mullan M. beta-Amyloid-mediated vasoactivity and vascular endothelial damage. Nature. 380: 168-71. PMID 8600393 DOI: 10.1038/380168A0 |
0.333 |
|
| 1996 |
Crawford F, Scibelli P, Duara R, Barker B, Fallin D, Gold M, Hoyne J, Sevush S, Mullan M. 500 Familial and population based studies of APOE and APOCI in AD Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80502-1 |
0.528 |
|
| 1996 |
Cantillon M, Barker W, Harwood D, Mullan M, Duara R. Phenotype of depression in Alzheimer's disease (AD) with APOE genotype Biological Psychiatry. 39: 661. DOI: 10.1016/0006-3223(96)84484-2 |
0.4 |
|
| 1995 |
Poduslo SE, Riggs D, Schwankhaus J, Osborne A, Crawford F, Mullan M. Association of apolipoprotein E but not B with Alzheimer's disease. Human Genetics. 96: 597-600. PMID 8530010 DOI: 10.1007/Bf00197418 |
0.54 |
|
| 1995 |
Crawford F, Hoyne J, Diaz P, Osborne A, Dorotheo J, Sheehan D, Mullan M. Occurrence of the Cys311 DRD2 variant in a pedigree multiply affected with panic disorder. American Journal of Medical Genetics. 60: 332-4. PMID 7485271 DOI: 10.1002/Ajmg.1320600414 |
0.446 |
|
| 1995 |
Mullan M, Bennett C, Figueredo C, Hughes D, Mant R, Owen M, Warren A, McInnis M, Marshall A, Lantos P. Clinical features of early onset, familial Alzheimer's disease linked to chromosome 14. American Journal of Medical Genetics. 60: 44-52. PMID 7485234 DOI: 10.1002/Ajmg.1320600109 |
0.383 |
|
| 1995 |
Bennett C, Crawford F, Osborne A, Diaz P, Hoyne J, Lopez R, Roques P, Duara R, Rossor M, Mullan M. Evidence that the APOE locus influences rate of disease progression in late onset familial Alzheimer's Disease but is not causative. American Journal of Medical Genetics. 60: 1-6. PMID 7485228 DOI: 10.1002/Ajmg.1320600102 |
0.554 |
|
| 1994 |
Mullan M, Crawford F, Buchanan J. Technical feasibility of genetic testing for Alzheimer's disease. Alzheimer Disease and Associated Disorders. 8: 102-15. PMID 8060603 DOI: 10.1097/00002093-199408020-00007 |
0.576 |
|
| 1994 |
Mullan M, Crawford F. The molecular genetics of Alzheimer's disease. Molecular Neurobiology. 9: 15-22. PMID 7888092 DOI: 10.1007/Bf02816100 |
0.343 |
|
| 1994 |
Crawford F, Bennett C, Osborne A, Diaz P, Mullan M. Age of onset and genetic predisposition in familial Alzheimer's disease Neurobiology of Aging. 15. DOI: 10.1016/0197-4580(94)92980-7 |
0.526 |
|
| 1993 |
Kennedy AM, Newman S, McCaddon A, Ball J, Roques P, Mullan M, Hardy J, Chartier-Harlin MC, Frackowiak RS, Warrington EK. Familial Alzheimer's disease. A pedigree with a mis-sense mutation in the amyloid precursor protein gene (amyloid precursor protein 717 valine-->glycine). Brain : a Journal of Neurology. 116: 309-24. PMID 8461968 DOI: 10.1093/Brain/116.2.309 |
0.687 |
|
| 1993 |
Brown J, Gydesen S, Sorensen SA, Brun A, Smith S, Houlden H, Twells R, Mullan M, Rossor M, Collinge J. Genetic characterization of a familial non-specific dementia originating in Jutland, Denmark. Journal of the Neurological Sciences. 114: 138-43. PMID 8445394 DOI: 10.1016/0022-510X(93)90288-A |
0.545 |
|
| 1993 |
Houlden H, Crawford F, Rossor M, Mullan M. Screening for the APP codon 670/671 mutations in Alzheimer's disease. Neuroscience Letters. 154: 161-2. PMID 8395665 DOI: 10.1016/0304-3940(93)90196-R |
0.547 |
|
| 1993 |
Mullan M, Houlden H, Crawford F, Kennedy A, Rogues P, Rossor M. Age of onset in familial early onset Alzheimer's disease correlates with genetic aetiology. American Journal of Medical Genetics. 48: 129-30. PMID 8291565 DOI: 10.1002/Ajmg.1320480303 |
0.514 |
|
| 1993 |
Mullan M, Tsuji S, Miki T, Katsuya T, Naruse S, Kaneko K, Shimizu T, Kojima T, Nakano I, Ogihara T. Clinical comparison of Alzheimer's disease in pedigrees with the codon 717 Val-->Ile mutation in the amyloid precursor protein gene. Neurobiology of Aging. 14: 407-19. PMID 8247223 DOI: 10.1016/0197-4580(93)90099-W |
0.384 |
|
| 1993 |
Mullan M, Crawford F. Genetic and molecular advances in Alzheimer's disease. Trends in Neurosciences. 16: 398-403. PMID 7504354 DOI: 10.1016/0166-2236(93)90007-9 |
0.565 |
|
| 1992 |
Lantos PL, Luthert PJ, Hanger D, Anderton BH, Mullan M, Rossor M. Familial Alzheimer's disease with the amyloid precursor protein position 717 mutation and sporadic Alzheimer's disease have the same cytoskeletal pathology. Neuroscience Letters. 137: 221-4. PMID 1584463 DOI: 10.1016/0304-3940(92)90408-Y |
0.456 |
|
| 1992 |
Crawford F, Chartier-Harlin MC, Mullan M, Hardy J, Delacourte A, Arnott G. Alzheimer's--a correction. Nature. 356: 390. PMID 1557118 DOI: 10.1038/356390B0 |
0.723 |
|
| 1992 |
Mullan M. Familial Alzheimer's disease: second gene locus located. Bmj (Clinical Research Ed.). 305: 1108-9. PMID 1463941 DOI: 10.1136/Bmj.305.6862.1108 |
0.366 |
|
| 1992 |
Hardy J, Mullan M. Alzheimer's disease. In search of the soluble. Nature. 359: 268-9. PMID 1406927 DOI: 10.1038/359268A0 |
0.387 |
|
| 1992 |
Collinge J, Brown J, Hardy J, Mullan M, Rossor MN, Baker H, Crow TJ, Lofthouse R, Poulter M, Ridley R. Inherited prion disease with 144 base pair gene insertion. 2. Clinical and pathological features. Brain : a Journal of Neurology. 115: 687-710. PMID 1352725 DOI: 10.1093/Brain/115.3.687 |
0.523 |
|
| 1992 |
Mullan M, Houlden H, Windelspecht M, Fidani L, Lombardi C, Diaz P, Rossor M, Crook R, Hardy J, Duff K. A locus for familial early-onset Alzheimer's disease on the long arm of chromosome 14, proximal to the alpha 1-antichymotrypsin gene. Nature Genetics. 2: 340-2. PMID 1303291 DOI: 10.1038/Ng1292-340 |
0.757 |
|
| 1992 |
Fidani L, Rooke K, Chartier-Harlin MC, Hughes D, Tanzi R, Mullan M, Roques P, Rossor M, Hardy J, Goate A. Screening for mutations in the open reading frame and promoter of the beta-amyloid precursor protein gene in familial Alzheimer's disease: identification of a further family with APP717 Val-->Ile. Human Molecular Genetics. 1: 165-8. PMID 1303172 DOI: 10.1093/Hmg/1.3.165 |
0.773 |
|
| 1992 |
Mullan M, Crawford F, Axelman K, Houlden H, Lilius L, Winblad B, Lannfelt L. A pathogenic mutation for probable Alzheimer's disease in the APP gene at the N-terminus of beta-amyloid. Nature Genetics. 1: 345-7. PMID 1302033 DOI: 10.1038/Ng0892-345 |
0.563 |
|
| 1992 |
Anderton B, Hanger D, Lantos P, Mullan M, Rossor M, Luthert P. Familial Alzheimer's disease with an APP717 point mutation and sporadic Alzheimer's disease have the same cytoskeletal pathology Neurobiology of Aging. 13: S57. DOI: 10.1016/0197-4580(92)90352-X |
0.407 |
|
| 1991 |
van Duijn CM, van Broeckhoven C, Hardy JA, Goate AM, Rossor MN, Vandenberghe A, Martin JJ, Hofman A, Mullan MJ. Evidence for allelic heterogeneity in familial early-onset Alzheimer's disease. The British Journal of Psychiatry : the Journal of Mental Science. 158: 471-4. PMID 2054561 DOI: 10.1192/Bjp.158.4.471 |
0.433 |
|
| 1991 |
Chartier-Harlin MC, Crawford F, Hamandi K, Mullan M, Goate A, Hardy J, Backhovens H, Martin JJ, Broeckhoven CV. Screening for the beta-amyloid precursor protein mutation (APP717: Val----Ile) in extended pedigrees with early onset Alzheimer's disease. Neuroscience Letters. 129: 134-5. PMID 1922963 DOI: 10.1016/0304-3940(91)90738-F |
0.77 |
|
| 1991 |
Pearson RC, Mullan M, Hardy J, Harrison PJ. Nicotine intake and Alzheimer's disease. Bmj (Clinical Research Ed.). 303: 361. PMID 1912783 DOI: 10.1136/Bmj.303.6798.361-A |
0.457 |
|
| 1991 |
Crawford F, Hardy J, Mullan M, Goate A, Hughes D, Fidani L, Roques P, Rossor M, Chartier-Harlin MC. Sequencing of exons 16 and 17 of the beta-amyloid precursor protein gene in 14 families with early onset Alzheimer's disease fails to reveal mutations in the beta-amyloid sequence. Neuroscience Letters. 133: 1-2. PMID 1791986 DOI: 10.1016/0304-3940(91)90042-R |
0.805 |
|
| 1991 |
Brown J, Smith S, Brun A, Collinge J, Gydesen S, Hardy J, Mullan M, Goate A. Genetic characterization of a novel familial dementia. Annals of the New York Academy of Sciences. 640: 181-3. PMID 1776737 DOI: 10.1111/J.1749-6632.1991.Tb00213.X |
0.644 |
|
| 1991 |
Mullan MJ, Giuffra L, Hardy JA, Ovenstone I, Haynes AR, James LA, Williamson R, Newton PJ, Owen MJ, Roques P. Clinical and pathologic features of chromosome 21-linked familial Alzheimer's disease. Annals of the New York Academy of Sciences. 640: 177-80. PMID 1776736 DOI: 10.1111/J.1749-6632.1991.Tb00212.X |
0.383 |
|
| 1991 |
Goate A, Chartier-Harlin MC, Mullan M, Brown J, Crawford F, Fidani L, Giuffra L, Haynes A, Irving N, James L. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. Nature. 349: 704-6. PMID 1671712 DOI: 10.1038/349704A0 |
0.814 |
|
| 1990 |
Goate AM, Hardy JA, Owen MJ, Haynes A, James L, Farrall M, Mullan MJ, Roques P, Rossor MN. Genetics of Alzheimer's disease. Advances in Neurology. 51: 197-8. PMID 2403711 |
0.528 |
|
| 1990 |
St George-Hyslop PH, Haines JL, Farrer LA, Polinsky R, Van Broeckhoven C, Goate A, McLachlan DR, Orr H, Bruni AC, Sorbi S, Rainero I, Foncin JF, Pollen D, Cantu JM, Tupler R, ... ... Mullan M, et al. Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder. Nature. 347: 194-7. PMID 2395471 DOI: 10.1038/347194A0 |
0.585 |
|
| 1990 |
Farrer LA, Myers RH, Cupples LA, St George-Hyslop PH, Bird TD, Rossor MN, Mullan MJ, Polinsky R, Nee L, Heston L. Transmission and age-at-onset patterns in familial Alzheimer's disease: evidence for heterogeneity. Neurology. 40: 395-403. PMID 2314579 DOI: 10.1097/00002093-199100510-00015 |
0.339 |
|
| 1990 |
Collinge J, Owen F, Poulter M, Leach M, Crow TJ, Rossor MN, Hardy J, Mullan MJ, Janota I, Lantos PL. Prion dementia without characteristic pathology. Lancet. 336: 7-9. PMID 1973256 DOI: 10.1016/0140-6736(90)91518-F |
0.54 |
|
| 1989 |
Hardy JA, Goate AM, Owen MJ, Mullan MJ, Rossor MN, Pearson RC. Modelling the occurrence and pathology of Alzheimer's disease. Neurobiology of Aging. 10: 429-31; discussion 4. PMID 2812201 DOI: 10.1016/0197-4580(89)90084-5 |
0.522 |
|
| 1989 |
Goate AM, Haynes AR, Owen MJ, Farrall M, James LA, Lai LY, Mullan MJ, Roques P, Rossor MN, Williamson R. Predisposing locus for Alzheimer's disease on chromosome 21. Lancet. 1: 352-5. PMID 2563508 DOI: 10.1016/S0140-6736(89)91725-X |
0.511 |
|
| 1989 |
Hardy JA, Owen MJ, Goate AM, James LA, Haynes AR, Rossor MN, Roques P, Mullan MJ. Molecular genetics of Alzheimer's disease. Biochemical Society Transactions. 17: 75-6. PMID 2523829 DOI: 10.1042/Bst0170075 |
0.518 |
|
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