| Year |
Citation |
Score |
| 2024 |
Leung YY, Lee WP, Kuzma AB, Nicaretta H, Valladares O, Gangadharan P, Qu L, Zhao Y, Ren Y, Cheng PL, Kuksa PP, Wang H, White H, Katanic Z, Bass L, ... ... Farrer LA, et al. Alzheimer's Disease Sequencing Project Release 4 Whole Genome Sequencing Dataset. Medrxiv : the Preprint Server For Health Sciences. PMID 39677464 DOI: 10.1101/2024.12.03.24317000 |
0.348 |
|
| 2024 |
Le Borgne J, Gomez L, Heikkinen S, Amin N, Ahmad S, Choi SH, Bis J, Grenier-Boley B, Rodriguez OG, Kleineidam L, Young J, Tripathi KP, Wang L, Varma A, Campos-Martin R, ... ... Farrer L, et al. X-chromosome-wide association study for Alzheimer's disease. Molecular Psychiatry. PMID 39633006 DOI: 10.1038/s41380-024-02838-5 |
0.351 |
|
| 2024 |
Lee WP, Choi SH, Shea MG, Cheng PL, Dombroski BA, Pitsillides AN, Heard-Costa NL, Wang H, Bulekova K, Kuzma AB, Leung YY, Farrell JJ, Lin H, Kunkle BW, Naj A, ... ... Farrer LA, et al. Association of common and rare variants with Alzheimer's disease in more than 13,000 diverse individuals with whole-genome sequencing from the Alzheimer's Disease Sequencing Project. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 39428839 DOI: 10.1002/alz.14283 |
0.413 |
|
| 2024 |
Kang M, Farrell JJ, Zhu C, Park H, Kang S, Seo EH, Choi KY, Jun GR, Won S, Gim J, Lee KH, Farrer LA. Whole-genome sequencing study in Koreans identifies novel loci for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 39428694 DOI: 10.1002/alz.14128 |
0.429 |
|
| 2024 |
Yuan J, Tao Q, Ang TFA, Liu C, Devine S, Auerbach SH, Mez J, Farrer LA, Qiu WQ, Au R. The Relationship between Framingham Stroke Risk Profile on Incident Dementia and Alzheimer's Disease: A 40-Year Follow-Up Study Highlighting Female Vulnerability. Annals of Neurology. PMID 39404028 DOI: 10.1002/ana.27108 |
0.348 |
|
| 2024 |
Shade LMP, Katsumata Y, Abner EL, Aung KZ, Claas SA, Qiao Q, Heberle BA, Brandon JA, Page ML, Hohman TJ, Mukherjee S, Mayeux RP, Farrer LA, Schellenberg GD, Haines JL, et al. GWAS of multiple neuropathology endophenotypes identifies new risk loci and provides insights into the genetic risk of dementia. Nature Genetics. PMID 39379761 DOI: 10.1038/s41588-024-01939-9 |
0.368 |
|
| 2024 |
O'Neill N, Stein TD, Olayinka OA, Empawi JA, Hu J, Tong T, Zhang X, Farrer LA. Cognitive resilience to Alzheimer's disease characterized by cell-type abundance. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 39262221 DOI: 10.1002/alz.14187 |
0.32 |
|
| 2024 |
Ray NR, Kunkle BW, Hamilton-Nelson K, Kurup JT, Rajabli F, Qiao M, Vardarajan BN, Cosacak MI, Kizil C, Jean-Francois M, Cuccaro M, Reyes-Dumeyer D, Cantwell L, Kuzma A, Vance JM, ... ... Farrer LA, et al. Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38958117 DOI: 10.1002/alz.13880 |
0.377 |
|
| 2024 |
Sahelijo N, Rajagopalan P, Qian L, Rahman R, Priyadarshi D, Goldstein D, Thomopoulos SI, Bennett DA, Farrer LA, Stein TD, Shen L, Huang H, Nho K, Andrew SJ, Davatzikos C, et al. Brain Cell-based Genetic Subtyping and Drug Repositioning for Alzheimer Disease. Medrxiv : the Preprint Server For Health Sciences. PMID 38947056 DOI: 10.1101/2024.06.21.24309255 |
0.385 |
|
| 2024 |
Wang Y, Huang J, Ang TFA, Zhu Y, Tao Q, Mez J, Alosco M, Denis GV, Belkina A, Gurnani A, Ross M, Gong B, Han J, Lunetta KL, Stein TD, ... ... Farrer LA, et al. The association between circulating CD34+CD133+ endothelial progenitor cells and reduced risk of Alzheimer's disease in the Framingham Heart Study. Exploration of Medicine. 5: 193-214. PMID 38854406 DOI: 10.37349/emed.2024.00216 |
0.33 |
|
| 2024 |
Vance JM, Farrer LA, Huang Y, Cruchaga C, Hyman BT, Pericak-Vance MA, Goate AM, Greicius MD, Griswold AJ, Haines JL, Tcw J, Schellenberg GD, Tsai LH, Herz J, Holtzman DM. Report of the APOE4 National Institute on Aging/Alzheimer Disease Sequencing Project Consortium Working Group: Reducing APOE4 in Carriers is a Therapeutic Goal for Alzheimer's Disease. Annals of Neurology. PMID 38180638 DOI: 10.1002/ana.26864 |
0.426 |
|
| 2023 |
Montoliu-Gaya L, Alosco ML, Yhang E, Tripodis Y, Sconzo D, Ally M, Grötschel L, Ashton NJ, Lantero-Rodriguez J, Sauer M, Gomes B, Nilsson J, Brinkmalm G, Sugarman MA, Aparicio HJ, ... ... Farrer L, et al. Optimal blood tau species for the detection of Alzheimer's disease neuropathology: an immunoprecipitation mass spectrometry and autopsy study. Acta Neuropathologica. 147: 5. PMID 38159140 DOI: 10.1007/s00401-023-02660-3 |
0.352 |
|
| 2023 |
Belloy ME, Andrews SJ, Le Guen Y, Cuccaro M, Farrer LA, Napolioni V, Greicius MD. APOE Genotype and Alzheimer Disease Risk Across Age, Sex, and Population Ancestry. Jama Neurology. PMID 37930705 DOI: 10.1001/jamaneurol.2023.3599 |
0.453 |
|
| 2023 |
Lee WP, Wang H, Dombroski B, Cheng PL, Tucci A, Si YQ, Farrell J, Tzeng JY, Leung YY, Malamon J, Wang LS, Vardarajan B, Farrer L, Schellenberg G, Project TADSPTAD. Structural Variation Detection and Association Analysis of Whole-Genome-Sequence Data from 16,905 Alzheimer's Diseases Sequencing Project Subjects. Research Square. PMID 37886469 DOI: 10.21203/rs.3.rs-3353179/v1 |
0.463 |
|
| 2023 |
Tao Q, Zhang C, Mercier G, Lunetta K, Ang TFA, Akhter-Khan S, Zhang Z, Taylor A, Killiany RJ, Alosco M, Mez J, Au R, Zhang X, Farrer LA, Qiu WWQ. Identification of an ε4-specific blood-based molecular pathway for Alzheimer's disease risk. Alzheimer's & Dementia (Amsterdam, Netherlands). 15: e12490. PMID 37854772 DOI: 10.1002/dad2.12490 |
0.349 |
|
| 2023 |
Huang J, Wang Y, Stein TD, Ang TFA, Zhu Y, Tao Q, Lunetta KL, Mez J, Au R, Farrer LA, Qiu WQ, Zhang X. The impact of blood MCP-1 levels on Alzheimer's disease with genetic variation of UNC5C and NAV3 loci. Research Square. PMID 37841863 DOI: 10.21203/rs.3.rs-3376348/v1 |
0.367 |
|
| 2023 |
Wang H, Dombroski BA, Cheng PL, Tucci A, Si YQ, Farrell JJ, Tzeng JY, Leung YY, Malamon JS, Wang LS, Vardarajan BN, Farrer LA, Schellenberg GD, Lee WP. Structural Variation Detection and Association Analysis of Whole-Genome-Sequence Data from 16,905 Alzheimer's Diseases Sequencing Project Subjects. Medrxiv : the Preprint Server For Health Sciences. PMID 37745545 DOI: 10.1101/2023.09.13.23295505 |
0.47 |
|
| 2023 |
Ray NR, Kunkle BW, Hamilton-Nelson K, Kurup JT, Rajabli F, Cosacak MI, Kizil C, Jean-Francois M, Cuccaro M, Reyes-Dumeyer D, Cantwell L, Kuzma A, Vance JM, Gao S, Hendrie HC, ... ... Farrer LA, et al. Extended genome-wide association study employing the African Genome Resources Panel identifies novel susceptibility loci for Alzheimer's Disease in individuals of African ancestry. Medrxiv : the Preprint Server For Health Sciences. PMID 37693582 DOI: 10.1101/2023.08.29.23294774 |
0.379 |
|
| 2023 |
Lee WP, Choi SH, Shea MG, Cheng PL, Dombroski BA, Pitsillides AN, Heard-Costa NL, Wang H, Bulekova K, Kuzma AB, Leung YY, Farrell JJ, Lin H, Naj A, Blue EE, ... ... Farrer LA, et al. Association of Common and Rare Variants with Alzheimer's Disease in over 13,000 Diverse Individuals with Whole-Genome Sequencing from the Alzheimer's Disease Sequencing Project. Medrxiv : the Preprint Server For Health Sciences. PMID 37693521 DOI: 10.1101/2023.09.01.23294953 |
0.416 |
|
| 2023 |
Park JY, Lee JJ, Lee Y, Lee D, Gim J, Farrer L, Lee KH, Won S. Machine learning-based quantification for disease uncertainty increases the statistical power of genetic association studies. Bioinformatics (Oxford, England). PMID 37665736 DOI: 10.1093/bioinformatics/btad534 |
0.352 |
|
| 2023 |
Logue MW, Dasgupta S, Farrer LA. Genetics of Alzheimer's Disease in the African American Population. Journal of Clinical Medicine. 12. PMID 37629231 DOI: 10.3390/jcm12165189 |
0.427 |
|
| 2023 |
Tejeda M, Farrell J, Zhu C, Wetzler L, Lunetta KL, Bush WS, Martin ER, Wang LS, Schellenberg GD, Pericak-Vance MA, Haines JL, Farrer LA, Sherva R. DNA from multiple viral species is associated with Alzheimer's disease risk. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37578203 DOI: 10.1002/alz.13414 |
0.384 |
|
| 2023 |
Rajabli F, Benchek P, Tosto G, Kushch N, Sha J, Bazemore K, Zhu C, Lee WP, Haut J, Hamilton-Nelson KL, Wheeler NR, Zhao Y, Farrell JJ, Grunin MA, Leung YY, ... ... Farrer LA, et al. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies and nominates ancestry-specific loci , , and as novel risk loci for Alzheimer's disease: the Alzheimer's Disease Genetics Consortium. Medrxiv : the Preprint Server For Health Sciences. PMID 37461624 DOI: 10.1101/2023.07.06.23292311 |
0.407 |
|
| 2023 |
Kang M, Ang TFA, Devine SA, Sherva R, Mukherjee S, Trittschuh EH, Gibbons LE, Scollard P, Lee M, Choi SE, Klinedinst B, Nakano C, Dumitrescu LC, Durant A, Hohman TJ, ... ... Farrer LA, et al. A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores. Molecular Neurodegeneration. 18: 40. PMID 37349795 DOI: 10.1186/s13024-023-00633-4 |
0.434 |
|
| 2023 |
Li D, Farrell JJ, Mez J, Martin ER, Bush WS, Ruiz A, Boada M, de Rojas I, Mayeux R, Haines JL, Vance MAP, Wang LS, Schellenberg GD, Lunetta KL, Farrer LA. Novel loci for Alzheimer's disease identified by a genome-wide association study in Ashkenazi Jews. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37260021 DOI: 10.1002/alz.13117 |
0.453 |
|
| 2023 |
Chung J, Sahelijo N, Maruyama T, Hu J, Panitch R, Xia W, Mez J, Stein TD, Saykin AJ, Takeyama H, Farrer LA, Crane PK, Nho K, Jun GR. Alzheimer's disease heterogeneity explained by polygenic risk scores derived from brain transcriptomic profiles. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37166019 DOI: 10.1002/alz.13069 |
0.384 |
|
| 2023 |
Bai H, Naj AC, Benchek P, Dumitrescu L, Hohman T, Hamilton-Nelson K, Kallianpur AR, Griswold AJ, Vardarajan B, Martin ER, Beecham GW, Below JE, Schellenberg G, Mayeux R, Farrer L, et al. A haptoglobin (HP) structural variant alters the effect of APOE alleles on Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 37051669 DOI: 10.1002/alz.13050 |
0.361 |
|
| 2023 |
Le Guen Y, Raulin AC, Logue MW, Sherva R, Belloy ME, Eger SJ, Chen A, Kennedy G, Kuchenbecker L, O'Leary JP, Zhang R, Merritt VC, Panizzon MS, Hauger RL, Gaziano JM, ... ... Farrer LA, et al. Association of African Ancestry-Specific APOE Missense Variant R145C With Risk of Alzheimer Disease. Jama. 329: 551-560. PMID 36809323 DOI: 10.1001/jama.2023.0268 |
0.428 |
|
| 2023 |
Puri S, Hu J, Sun Z, Lin M, Stein TD, Farrer LA, Wolozin B, Zhang X. Identification of circRNAs linked to Alzheimer's disease and related dementias. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36795937 DOI: 10.1002/alz.12960 |
0.37 |
|
| 2023 |
Wang Y, Huang J, Ang TFA, Zhu Y, Tao Q, Mez J, Alosco M, Denis GV, Belkina A, Gurnani A, Ross M, Gong B, Han J, Lunetta KL, Stein TD, ... ... Farrer LA, et al. Circulating Endothelial Progenitor Cells Reduce the Risk of Alzheimer's Disease. Medrxiv : the Preprint Server For Health Sciences. PMID 36711847 DOI: 10.1101/2023.01.16.23284571 |
0.355 |
|
| 2023 |
Marini S, Chung J, Han X, Sun X, Parodi L, Farrer L, Rosand J, Romer JR, Anderson C. Pleiotropy analysis between lobar intracerebral hemorrhage and CSF β-amyloid highlights new and established associations. International Journal of Stroke : Official Journal of the International Stroke Society. 17474930231155816. PMID 36705426 DOI: 10.1177/17474930231155816 |
0.365 |
|
| 2022 |
Huang J, Tao Q, Ang TFA, Farrell J, Zhu C, Wang Y, Stein TD, Lunetta KL, Massaro J, Mez J, Au R, Farrer LA, Qiu WQ, Zhang X. The impact of increasing levels of blood C-reactive protein on the inflammatory loci SPI1 and CD33 in Alzheimer's disease. Translational Psychiatry. 12: 523. PMID 36550123 DOI: 10.1038/s41398-022-02281-6 |
0.444 |
|
| 2022 |
Sherva R, Zhang R, Sahelijo N, Jun G, Anglin T, Chanfreau C, Cho K, Fonda JR, Gaziano JM, Harrington KM, Ho YL, Kremen WS, Litkowski E, Lynch J, Neale Z, ... ... Farrer LA, et al. African ancestry GWAS of dementia in a large military cohort identifies significant risk loci. Molecular Psychiatry. PMID 36543923 DOI: 10.1038/s41380-022-01890-3 |
0.482 |
|
| 2022 |
Rajabli F, Tosto G, Hamilton-Nelson KL, Kunkle BW, Vardarajan BN, Naj A, Whitehead PG, Gardner OK, Bush WS, Sariya S, Mayeux RP, Farrer LA, Cuccaro ML, Vance JM, Griswold AJ, et al. Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36539198 DOI: 10.1002/alz.12865 |
0.332 |
|
| 2022 |
Holstege H, Hulsman M, Charbonnier C, Grenier-Boley B, Quenez O, Grozeva D, van Rooij JGJ, Sims R, Ahmad S, Amin N, Norsworthy PJ, Dols-Icardo O, Hummerich H, Kawalia A, Amouyel P, ... ... Farrer LA, et al. Exome sequencing identifies rare damaging variants in ATP8B4 and ABCA1 as risk factors for Alzheimer's disease. Nature Genetics. PMID 36411364 DOI: 10.1038/s41588-022-01208-7 |
0.462 |
|
| 2022 |
Huang J, Stein TD, Wang Y, Ang TFA, Tao Q, Lunetta KL, Massaro J, Akhter-Khan SC, Mez J, Au R, Farrer LA, Zhang X, Qiu WQ. Blood levels of MCP-1 modulate the genetic risks of Alzheimer's disease mediated by HLA-DRB1 and APOE for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36396603 DOI: 10.1002/alz.12851 |
0.372 |
|
| 2022 |
Chung J, Das A, Sun X, Sobreira DR, Leung YY, Igartua C, Mozaffari S, Chou YF, Thiagalingam S, Mez J, Zhang X, Jun GR, Stein TD, Kunkle BW, Martin ER, ... ... Farrer LA, et al. Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35770850 DOI: 10.1002/alz.12719 |
0.383 |
|
| 2022 |
You Y, Hersh SW, Aslebagh R, Shaffer SA, Ikezu S, Mez J, Lunetta KL, Logue MW, Farrer LA, Ikezu T. Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells. Aging Cell. e13617. PMID 35567427 DOI: 10.1111/acel.13617 |
0.426 |
|
| 2022 |
Eissman JM, Dumitrescu L, Mahoney ER, Smith AN, Mukherjee S, Lee ML, Scollard P, Choi SE, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski CC, ... ... Farrer LA, et al. Sex differences in the genetic architecture of cognitive resilience to Alzheimer's disease. Brain : a Journal of Neurology. PMID 35552371 DOI: 10.1093/brain/awac177 |
0.314 |
|
| 2022 |
Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, ... ... Farrer LA, et al. New insights into the genetic etiology of Alzheimer's disease and related dementias. Nature Genetics. PMID 35379992 DOI: 10.1038/s41588-022-01024-z |
0.459 |
|
| 2022 |
Zhang X, Tong T, Chang A, Ang TFA, Tao Q, Auerbach S, Devine S, Qiu WQ, Mez J, Massaro J, Lunetta KL, Au R, Farrer LA. Midlife lipid and glucose levels are associated with Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35319157 DOI: 10.1002/alz.12641 |
0.368 |
|
| 2022 |
Vardarajan BN, Reyes-Dumeyer D, Piriz AL, Lantigua RA, Medrano M, Rivera D, Jiménez-Velázquez IZ, Martin E, Pericak-Vance MA, Bush W, Farrer L, Haines JL, Wang LS, Leung YY, Schellenberg G, et al. Progranulin mutations in clinical and neuropathological Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35258170 DOI: 10.1002/alz.12567 |
0.383 |
|
| 2022 |
Jin B, Capra JA, Benchek P, Wheeler NR, Naj AC, Hamilton-Nelson KL, Farrell JJ, Leung YY, Kunkle BW, Vardarajan BN, Schellenberg GD, Mayeux R, Wang LS, Farrer LA, Pericak-Vance M, et al. An association test of the spatial distribution of rare missense variants within protein structures identify Alzheimer's disease-related patterns. Genome Research. PMID 35210353 DOI: 10.1101/gr.276069.121 |
0.374 |
|
| 2022 |
Jun GR, You Y, Zhu C, Meng G, Chung J, Panitch R, Hu J, Xia W, Bennett DA, Foroud TM, Wang LS, Haines JL, Mayeux R, Pericak-Vance MA, Schellenberg GD, ... ... Farrer LA, et al. Protein phosphatase 2A and complement component 4 are linked to the protective effect of APOE ɛ2 for Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35142023 DOI: 10.1002/alz.12607 |
0.401 |
|
| 2022 |
Panitch R, Hu J, Xia W, Bennett DA, Stein TD, Farrer LA, Jun GR. Blood and brain transcriptome analysis reveals APOE genotype-mediated and immune-related pathways involved in Alzheimer disease. Alzheimer's Research & Therapy. 14: 30. PMID 35139885 DOI: 10.1186/s13195-022-00975-z |
0.307 |
|
| 2021 |
Xue D, Bush WS, Renton AE, Marcora EA, Bis JC, Kunkle BW, Boerwinkle E, DeStefano AL, Farrer L, Goate A, Mayeux R, Pericak-Vance M, Schellenberg G, Seshadri S, et al. Large-scale sequencing studies expand the known genetic architecture of Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12255. PMID 35005195 DOI: 10.1002/dad2.12255 |
0.386 |
|
| 2021 |
Hersh SW, You Y, Aslebagh R, Shaffer SA, Ikezu S, Mez J, Lunetta KL, Logue MW, Farrer LA, Ikezu T. Alzheimer's disease associated AKAP9 I2558M mutation alters posttranslational modification and interactome of tau and cellular functions in CRISPR-edited human neuronal cells. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 17: e058592. PMID 34971140 DOI: 10.1002/alz.058592 |
0.474 |
|
| 2021 |
Park JY, Lee D, Lee JJ, Gim J, Gunasekaran TI, Choi KY, Kang S, Do AR, Jo J, Park J, Park K, Li D, Lee S, Kim H, Dhanasingh I, ... ... Farrer LA, et al. A missense variant in SHARPIN mediates Alzheimer's disease-specific brain damages. Translational Psychiatry. 11: 590. PMID 34785643 DOI: 10.1038/s41398-021-01680-5 |
0.428 |
|
| 2021 |
Panitch R, Hu J, Chung J, Zhu C, Meng G, Xia W, Bennett DA, Lunetta KL, Ikezu T, Au R, Stein TD, Farrer LA, Jun GR. Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE ε2 protective effect in Alzheimer disease. Molecular Psychiatry. PMID 34480088 DOI: 10.1038/s41380-021-01266-z |
0.382 |
|
| 2021 |
Zhang X, Farrell JJ, Tong T, Hu J, Zhu C, Wang LS, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Farrer LA. Association of mitochondrial variants and haplogroups identified by whole exome sequencing with Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34152079 DOI: 10.1002/alz.12396 |
0.364 |
|
| 2021 |
de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hernández I, Montrreal L, Antúnez C, Antonell A, Tankard RM, Bis JC, ... ... Farrer LA, et al. Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nature Communications. 12: 3417. PMID 34099642 DOI: 10.1038/s41467-021-22491-8 |
0.382 |
|
| 2021 |
Patel D, Zhang X, Farrell JJ, Chung J, Stein TD, Lunetta KL, Farrer LA. Cell-type-specific expression quantitative trait loci associated with Alzheimer disease in blood and brain tissue. Translational Psychiatry. 11: 250. PMID 33907181 DOI: 10.1038/s41398-021-01373-z |
0.322 |
|
| 2020 |
Kunkle BW, Schmidt M, Klein HU, Naj AC, Hamilton-Nelson KL, Larson EB, Evans DA, De Jager PL, Crane PK, Buxbaum JD, Ertekin-Taner N, Barnes LL, Fallin MD, Manly JJ, Go RCP, ... ... Farrer LA, et al. Novel Alzheimer Disease Risk Loci and Pathways in African American Individuals Using the African Genome Resources Panel: A Meta-analysis. Jama Neurology. PMID 33074286 DOI: 10.1001/jamaneurol.2020.3536 |
0.351 |
|
| 2020 |
Lancour D, Dupuis J, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GC, Crovella M, Farrer LA, Kasif S. Analysis of brain region-specific co-expression networks reveals clustering of established and novel genes associated with Alzheimer disease. Alzheimer's Research & Therapy. 12: 103. PMID 32878640 DOI: 10.1186/S13195-020-00674-7 |
0.366 |
|
| 2020 |
Dumitrescu L, Mahoney ER, Mukherjee S, Lee ML, Bush WS, Engelman CD, Lu Q, Fardo DW, Trittschuh EH, Mez J, Kaczorowski C, Hernandez Saucedo H, Widaman KF, Buckley R, Properzi M, ... ... Farrer LA, et al. Genetic variants and functional pathways associated with resilience to Alzheimer's disease. Brain : a Journal of Neurology. 143: 2561-2575. PMID 32844198 DOI: 10.1093/Brain/Awaa209 |
0.318 |
|
| 2020 |
Fan CC, Banks SJ, Thompson WK, Chen CH, McEvoy LK, Tan CH, Kukull W, Bennett DA, Farrer LA, Mayeux R, Schellenberg GD, Andreassen OA, Desikan R, Dale AM. Sex-dependent autosomal effects on clinical progression of Alzheimer's disease. Brain : a Journal of Neurology. PMID 32591829 DOI: 10.1093/Brain/Awaa164 |
0.352 |
|
| 2020 |
Sherva R, Gross A, Mukherjee S, Koesterer R, Amouyel P, Bellenguez C, Dufouil C, Bennett DA, Chibnik L, Cruchaga C, Del-Aguila J, Farrer LA, Mayeux R, Munsie L, Winslow A, et al. Genome-wide association study of rate of cognitive decline in Alzheimer's disease patients identifies novel genes and pathways. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32573913 DOI: 10.1002/Alz.12106 |
0.38 |
|
| 2020 |
Reiman EM, Arboleda-Velasquez JF, Quiroz YT, Huentelman MJ, Beach TG, Caselli RJ, Chen Y, Su Y, Myers AJ, Hardy J, Paul Vonsattel J, Younkin SG, Bennett DA, De Jager PL, Larson EB, ... ... Farrer LA, et al. Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study. Nature Communications. 11: 667. PMID 32015339 DOI: 10.1038/S41467-019-14279-8 |
0.414 |
|
| 2019 |
Choi KY, Lee JJ, Gunasekaran TI, Kang S, Lee W, Jeong J, Lim HJ, Zhang X, Zhu C, Won SY, Choi YY, Seo EH, Lee SC, Gim J, Chung JY, ... ... Farrer LA, et al. Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of ε4 on Alzheimer's Disease Risk in a Multiracial Sample. Journal of Clinical Medicine. 8. PMID 31426376 DOI: 10.3390/Jcm8081236 |
0.414 |
|
| 2019 |
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Farrer LA, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. PMID 31417202 DOI: 10.1038/s41588-019-0495-7 |
0.357 |
|
| 2019 |
Ma Y, Jun GR, Zhang X, Chung J, Naj AC, Chen Y, Bellenguez C, Hamilton-Nelson K, Martin ER, Kunkle BW, Bis JC, Debette S, DeStefano AL, Fornage M, Nicolas G, ... ... Farrer LA, et al. Analysis of Whole-Exome Sequencing Data for Alzheimer Disease Stratified by APOE Genotype. Jama Neurology. PMID 31180460 DOI: 10.1001/Jamaneurol.2019.1456 |
0.478 |
|
| 2019 |
Ma Y, Jun GR, Chung J, Zhang X, Kunkle BW, Naj AC, White CC, Bennett DA, De Jager PL, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GD, Farrer LA, et al. CpG-related SNPs in the MS4A region have a dose-dependent effect on risk of late-onset Alzheimer disease. Aging Cell. e12964. PMID 31144443 DOI: 10.1111/Acel.12964 |
0.376 |
|
| 2019 |
Patel D, Mez J, Vardarajan BN, Staley L, Chung J, Zhang X, Farrell JJ, Rynkiewicz MJ, Cannon-Albright LA, Teerlink CC, Stevens J, Corcoran C, Gonzalez Murcia JD, Lopez OL, Mayeux R, ... ... Farrer LA, et al. Association of Rare Coding Mutations With Alzheimer Disease and Other Dementias Among Adults of European Ancestry. Jama Network Open. 2: e191350. PMID 30924900 DOI: 10.1001/Jamanetworkopen.2019.1350 |
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| 2019 |
Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Farrer LA, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2 |
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| 2019 |
Chung J, Jun GR, Dupuis J, Farrer LA. Comparison of methods for multivariate gene-based association tests for complex diseases using common variants. European Journal of Human Genetics : Ejhg. PMID 30683923 DOI: 10.1038/S41431-018-0327-8 |
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| 2019 |
Li D, Farrell J, Farrer LA, Jun GR, Won S. P1-142: A GENOME-WIDE ASSOCIATION STUDY IMPLICATES EHPA6
FOR ALZHEIMER DISEASE IN FAMILY-BASED ANALYSIS Alzheimer's & Dementia. 15: P291-P292. DOI: 10.1016/j.jalz.2019.06.697 |
0.321 |
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| 2019 |
Patel D, Mez J, Vardarajan BN, Staley L, Chung J, Zhang X, Farrell J, Rynkiewicz MJ, Cannon-Albright L, Teerlink C, Stevens J, Corcoran C, Murcia JDG, Lopez OL, Mayeux R, ... ... Farrer LAA, et al. O3-13-01: Highly Penetrant Late-Onset Alzheimer Disease Variants In Notch3 In Ashkenazi Jews Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4696 |
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| 2019 |
Naj A, Sha J, Leonenko G, Chen Y, Chouraki V, Leber M, Sims R, Grenier-Boley B, Bis JC, Zhao Y, Kuzma AB, Kunkle BW, Karamujić-Čomić H, Lee SJVD, Bellenguez C, ... ... Farrer LA, et al. O2‐10‐06: Genome‐Wide Meta‐Analysis Of Late‐Onset Alzheimer'S Disease Using Rare Variant Imputation In 64,859 Subjects Identifies Risk Loci With Roles In Innate Immunity And Cardiovascular Traits: The International Genomics Of Alzheimer'S Project (Igap) Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4510 |
0.339 |
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| 2019 |
Zhang X, Farrell J, Zhu C, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, Farrer LAA, Sequencing AD. O2-10-04: Mitochondrial Variants And Haplogroups Associated With Late-Onset Alzheimer'S Disease Identified By Whole Exome Sequencing Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4508 |
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| 2019 |
Kunkle BW, Hamilton-Nelson KL, Gomez L, Jean-Francois M, Naj A, Wang L, Kuzma AB, Beecham GW, Bush WS, Hohman TJ, Vardarajan BN, Wang L, Mayeux R, Haines JL, Farrer LA, et al. P4-094: Exome-Wide Analysis Identifies Novel Sex-Specific Candidate Genes For Alzheimer Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3754 |
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Nicolaou M, Farrell J, Zhu C, Panitch R, Farrer LA, Jun GR. P3-436: Association Of Hla Subtypes With Neuropathologically Defined Alzheimer Disease Is Modulated By Apoe Genotype Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3470 |
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| 2019 |
Zhou H, Polimanti R, Yang B, Wang Q, Han S, Sherva R, Nunez Y, Zhao H, Farrer L, Kranzler H, Gelernter J. Genome-Wide Association Study Of Comorbid Alcohol Dependence And Major Depression European Neuropsychopharmacology. 29. DOI: 10.1016/J.Euroneuro.2017.08.338 |
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| 2018 |
Beecham GW, Vardarajan B, Blue E, Bush W, Jaworski J, Barral S, DeStefano A, Hamilton-Nelson K, Kunkle B, Martin ER, Naj A, Rajabli F, Reitz C, Thornton T, van Duijn C, ... ... Farrer LA, et al. Rare genetic variation implicated in non-Hispanic white families with Alzheimer disease. Neurology. Genetics. 4: e286. PMID 30569016 DOI: 10.1212/Nxg.0000000000000286 |
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| 2018 |
Rajabli F, Feliciano BE, Celis K, Hamilton-Nelson KL, Whitehead PL, Adams LD, Bussies PL, Manrique CP, Rodriguez A, Rodriguez V, Starks T, Byfield GE, Sierra Lopez CB, McCauley JL, Acosta H, ... ... Farrer LA, et al. Ancestral origin of ApoE ε4 Alzheimer disease risk in Puerto Rican and African American populations. Plos Genetics. 14: e1007791. PMID 30517106 DOI: 10.1371/Journal.Pgen.1007791 |
0.314 |
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| 2018 |
Zhang X, Zhu C, Beecham G, Vardarajan BN, Ma Y, Lancour D, Farrell JJ, Chung J, Mayeux R, Haines JL, Schellenberg GD, Pericak-Vance MA, Lunetta KL, Farrer LA. A rare missense variant of CASP7 is associated with familial late-onset Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30503768 DOI: 10.1016/j.jalz.2018.10.005 |
0.457 |
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| 2018 |
Walters RK, Polimanti R, Johnson EC, McClintick JN, Adams MJ, Adkins AE, Aliev F, Bacanu SA, Batzler A, Bertelsen S, Biernacka JM, Bigdeli TB, Chen LS, Clarke TK, Chou YL, ... ... Farrer LA, et al. Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders. Nature Neuroscience. 21: 1656-1669. PMID 30482948 DOI: 10.1038/S41593-018-0275-1 |
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| 2018 |
Broce IJ, Tan CH, Fan CC, Jansen I, Savage JE, Witoelar A, Wen N, Hess CP, Dillon WP, Glastonbury CM, Glymour M, Yokoyama JS, Elahi FM, Rabinovici GD, Miller BL, ... ... Farrer LA, et al. Dissecting the genetic relationship between cardiovascular risk factors and Alzheimer's disease. Acta Neuropathologica. PMID 30413934 DOI: 10.1007/S00401-018-1928-6 |
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| 2018 |
Cherry JD, Mez J, Crary JF, Tripodis Y, Alvarez VE, Mahar I, Huber BR, Alosco ML, Nicks R, Abdolmohammadi B, Kiernan PT, Evers L, Svirsky S, Babcock K, Gardner HM, ... ... Farrer LA, et al. Variation in TMEM106B in chronic traumatic encephalopathy. Acta Neuropathologica Communications. 6: 115. PMID 30390709 DOI: 10.1186/S40478-018-0619-9 |
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| 2018 |
Logue MW, Lancour D, Farrell J, Simkina I, Fallin MD, Lunetta KL, Farrer LA. Targeted Sequencing of Alzheimer Disease Genes in African Americans Implicates Novel Risk Variants. Frontiers in Neuroscience. 12: 592. PMID 30210277 DOI: 10.3389/fnins.2018.00592 |
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| 2018 |
Gusareva ES, Twizere JC, Sleegers K, Dourlen P, Abisambra JF, Meier S, Cloyd R, Weiss B, Dermaut B, Bessonov K, van der Lee SJ, Carrasquillo MM, Katsumata Y, Cherkaoui M, Asselbergh B, ... ... Farrer LA, et al. Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease. Neurobiology of Aging. PMID 30201328 DOI: 10.1016/J.Neurobiolaging.2018.08.001 |
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| 2018 |
Bis JC, Jian X, Kunkle BW, Chen Y, Hamilton-Nelson KL, Bush WS, Salerno WJ, Lancour D, Ma Y, Renton AE, Marcora E, Farrell JJ, Zhao Y, Qu L, Ahmad S, ... ... Farrer LA, et al. Whole exome sequencing study identifies novel rare and common Alzheimer's-Associated variants involved in immune response and transcriptional regulation. Molecular Psychiatry. PMID 30108311 DOI: 10.1038/S41380-018-0112-7 |
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| 2018 |
Vardarajan BN, Barral S, Jaworski J, Beecham GW, Blue E, Tosto G, Reyes-Dumeyer D, Medrano M, Lantigua R, Naj A, Thornton T, DeStefano A, Martin E, Wang LS, Brown L, ... ... Farrer L, et al. Whole genome sequencing of Caribbean Hispanic families with late-onset Alzheimer's disease. Annals of Clinical and Translational Neurology. 5: 406-417. PMID 29688227 DOI: 10.1002/Acn3.537 |
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Lancour D, Naj A, Mayeux R, Haines JL, Pericak-Vance MA, Schellenberg GC, Crovella M, Farrer LA, Kasif S. One for all and all for One: Improving replication of genetic studies through network diffusion. Plos Genetics. 14: e1007306. PMID 29684019 DOI: 10.1371/Journal.Pgen.1007306 |
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| 2018 |
Ikezu T, Chen C, DeLeo AM, Zeldich E, Fallin MD, Kanaan NM, Lunetta KL, Abraham CR, Logue MW, Farrer LA. Tau Phosphorylation is Impacted by Rare AKAP9 Mutations Associated with Alzheimer Disease in African Americans. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. PMID 29516269 DOI: 10.1007/S11481-018-9781-X |
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| 2018 |
Blue EE, Bis JC, Dorschner MO, Tsuang DW, Barral SM, Beecham G, Below JE, Bush WS, Butkiewicz M, Cruchaga C, DeStefano A, Farrer LA, Goate A, Haines J, Jaworski J, et al. Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project. Dementia and Geriatric Cognitive Disorders. 45: 1-17. PMID 29486463 DOI: 10.1159/000485503 |
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Chung J, Zhang X, Allen M, Wang X, Ma Y, Beecham G, Montine TJ, Younkin SG, Dickson DW, Golde TE, Price ND, Ertekin-Taner N, Lunetta KL, Mez J, ... ... Farrer LA, et al. Genome-wide pleiotropy analysis of neuropathological traits related to Alzheimer's disease. Alzheimer's Research & Therapy. 10: 22. PMID 29458411 DOI: 10.1186/S13195-018-0349-Z |
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| 2018 |
Logue MW, Lancour D, Farrell J, Fallin MD, Lunetta KL, Farrer LAA. P2-125: Targeted Sequencing Of African American Alzheimer'S Disease Risk Genes Implicates Several Potential Ad Risk Variants Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.811 |
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Patel D, Chung J, Mez J, Zhang X, Haines JL, Pericak-Vance MA, Schellenberg G, Lunetta KL, Farrer LA. O5-04-02: Rare Coding Mutations Associated With Alzheimer Disease And Other Dementias Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.3014 |
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| 2018 |
Zhang X, Zhou TJ, Farrell J, Chung J, Naj AC, Lunetta KL, Farrer LA. P3-108: Identification Of Mitochondrial Variants Associated With Late-Onset Alzheimer'S Disease Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1465 |
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Chung J, Wang X, Maruyama T, Ma Y, Zhang X, Mez J, Sherva R, Takeyama H, Lunetta KL, Farrer LA, Jun GR. Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29274321 DOI: 10.1016/J.Jalz.2017.11.006 |
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| 2017 |
Beecham GW, Bis JC, Martin ER, Choi SH, DeStefano AL, van Duijn CM, Fornage M, Gabriel SB, Koboldt DC, Larson DE, Naj AC, Psaty BM, Salerno W, Bush WS, Foroud TM, ... ... Farrer LA, et al. The Alzheimer's Disease Sequencing Project: Study design and sample selection. Neurology. Genetics. 3: e194. PMID 29184913 DOI: 10.1212/Nxg.0000000000000194 |
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| 2017 |
Rehker J, Rodhe J, Nesbitt RR, Boyle EA, Martin BK, Lord J, Karaca I, Naj A, Jessen F, Helisalmi S, Soininen H, Hiltunen M, Ramirez A, Scherer M, Farrer LA, et al. Caspase-8, association with Alzheimer's Disease and functional analysis of rare variants. Plos One. 12: e0185777. PMID 28985224 DOI: 10.1371/Journal.Pone.0185777 |
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| 2017 |
Kunkle BW, Vardarajan BN, Naj AC, Whitehead PL, Rolati S, Slifer S, Carney RM, Cuccaro ML, Vance JM, Gilbert JR, Wang LS, Farrer LA, Reitz C, Haines JL, Beecham GW, et al. Early-Onset Alzheimer Disease and Candidate Risk Genes Involved in Endolysosomal Transport. Jama Neurology. PMID 28738127 DOI: 10.1001/Jamaneurol.2017.1518 |
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Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Farrer LA, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916 |
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Huang KL, Marcora E, Pimenova AA, Di Narzo AF, Kapoor M, Jin SC, Harari O, Bertelsen S, Fairfax BP, Czajkowski J, Chouraki V, Grenier-Boley B, Bellenguez C, Deming Y, McKenzie A, ... ... Farrer LA, et al. A common haplotype lowers PU.1 expression in myeloid cells and delays onset of Alzheimer's disease. Nature Neuroscience. PMID 28628103 DOI: 10.1038/Nn.4587 |
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| 2017 |
Desikan RS, Fan CC, Wang Y, Schork AJ, Cabral HJ, Cupples LA, Thompson WK, Besser L, Kukull WA, Holland D, Chen CH, Brewer JB, Karow DS, Kauppi K, Witoelar A, ... ... Farrer LA, et al. Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score. Plos Medicine. 14: e1002258. PMID 28323831 DOI: 10.1371/Journal.Pmed.1002258 |
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Deming Y, Li Z, Kapoor M, Harari O, Del-Aguila JL, Black K, Carrell D, Cai Y, Fernandez MV, Budde J, Ma S, Saef B, Howells B, Huang KL, Bertelsen S, ... ... Farrer LA, et al. Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers. Acta Neuropathologica. PMID 28247064 DOI: 10.1007/s00401-017-1685-y |
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| 2017 |
Jun GR, Chung J, Mez J, Barber R, Beecham GW, Bennett DA, Buxbaum JD, Byrd GS, Carrasquillo MM, Crane PK, Cruchaga C, De Jager P, Ertekin-Taner N, Evans D, Fallin MD, ... ... Farrer LA, et al. Transethnic genome-wide scan identifies novel Alzheimer's disease loci. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28183528 DOI: 10.1016/J.Jalz.2016.12.012 |
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| 2017 |
Zhang X, Ma Y, Lancour D, Farrell J, Chung J, Mayeux R, Haines JL, Schellenberg GD, Pericak-Vance MA, Lunetta KL, Farrer LA. Novel Genetic Variants Associated With Familial Late-Onset Alzheimer Disease In The Alzheimer’S Disease Sequencing Project Alzheimers & Dementia. 13: 572. DOI: 10.1016/J.Jalz.2017.07.189 |
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| 2017 |
Logue MW, Chen C, Zeldich E, Fallin MD, Abraham CR, Ikezu T, Farrer LA. Tau Phosphorylation Is Impacted By Rare Ad-Associated Akap9 Mutations Specific To African Americans Alzheimers & Dementia. 13: 969. DOI: 10.1016/J.Jalz.2017.06.1302 |
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| 2017 |
Chung J, Wang X, Ma Y, Maruyama T, Kim M, Zhang X, Takeyama H, Mez J, Sherva R, Lunetta KL, Farrer LA, Jun GR. Genome-Wide Association Study Of Alzheimer Disease Endophenotypes At Preclinical And Mci Stages Alzheimers & Dementia. 13. DOI: 10.1016/J.Jalz.2017.06.062 |
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| 2016 |
Mez J, Chung J, Jun G, Kriegel J, Bourlas AP, Sherva R, Logue MW, Barnes LL, Bennett DA, Buxbaum JD, Byrd GS, Crane PK, Ertekin-Taner N, Evans D, Fallin MD, ... ... Farrer LA, et al. Two novel loci, COBL and SLC10A2, for Alzheimer's disease in African Americans. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27770636 DOI: 10.1016/J.Jalz.2016.09.002 |
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| 2016 |
Polimanti R, Wang Q, Meda SA, Patel KT, Pearlson GD, Zhao H, Farrer LA, Kranzler HR, Gelernter J. The Interplay Between Risky Sexual Behaviors and Alcohol Dependence: Genome-Wide Association and Neuroimaging Support for LHPP as a Risk Gene. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 27531626 DOI: 10.1038/npp.2016.153 |
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| 2016 |
Cukier HN, Kunkle BW, Vardarajan BN, Rolati S, Hamilton-Nelson KL, Kohli MA, Whitehead PL, Dombroski BA, Van Booven D, Lang R, Dykxhoorn DM, Farrer LA, Cuccaro ML, Vance JM, Gilbert JR, et al. ABCA7 frameshift deletion associated with Alzheimer disease in African Americans. Neurology. Genetics. 2: e79. PMID 27231719 DOI: 10.1016/J.Jalz.2016.06.305 |
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| 2016 |
Kohli MA, Cukier HN, Hamilton-Nelson KL, Rolati S, Kunkle BW, Whitehead PL, Züchner SL, Farrer LA, Martin ER, Beecham GW, Haines JL, Vance JM, Cuccaro ML, Gilbert JR, Schellenberg GD, et al. Segregation of a rare TTC3 variant in an extended family with late-onset Alzheimer disease. Neurology. Genetics. 2: e41. PMID 27066578 DOI: 10.1212/Nxg.0000000000000041 |
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| 2016 |
Ridge PG, Hoyt KB, Boehme K, Mukherjee S, Crane PK, Haines JL, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD, Kauwe JS. Assessment of the genetic variance of late-onset Alzheimer's disease. Neurobiology of Aging. PMID 27036079 DOI: 10.1016/J.Neurobiolaging.2016.02.024 |
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| 2016 |
Hohman TJ, Bush WS, Jiang L, Brown-Gentry KD, Torstenson ES, Dudek SM, Mukherjee S, Naj A, Kunkle BW, Ritchie MD, Martin ER, Schellenberg GD, Mayeux R, Farrer LA, Pericak-Vance MA, et al. Discovery of gene-gene interactions across multiple independent data sets of late onset Alzheimer disease from the Alzheimer Disease Genetics Consortium. Neurobiology of Aging. 38: 141-50. PMID 26827652 DOI: 10.1016/J.Neurobiolaging.2015.10.031 |
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| 2016 |
Xia LC, Farrell J, Zhang N, Salerno W, Malamon J, Murali SC, Wang W, Wang L, Farrer LA, Worley KC, Schellenberg GD. P1-129: Structural Variation (SV) in Heterogenous Whole-Genome Sequencing Data from 111 Families at Risk For Alzheimer's Disease: Alzheimer's Disease Sequencing Project SV Study Alzheimer's & Dementia. 12: P453-P453. DOI: 10.1016/j.jalz.2016.06.877 |
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| 2016 |
Chung J, Ma Y, Lunetta KL, Mez J, Beecham GW, Pericak-Vance MA, Haines JL, Mayeux R, Schellenberg GD, Jun GR, Farrer LA. Multivariate Phenotypes Association Study Of Neuropathological Features Of Alzheimer'S Disease And Related Dementias Alzheimers & Dementia. 12: 450. DOI: 10.1016/J.Jalz.2016.06.838 |
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| 2016 |
Huang K, Jin SC, Harari O, Kapoor M, Bertelsen S, Czajkowski J, Lambert j, Chouraki V, Bellenguez C, Grenier-Boley B, Deming Y, McKenzie A, Renton AE, Budde J, Del-Aguila JL, ... ... Farrer LA, et al. A Common Allele In Spi1 Lowers Risk And Delays Age At Onset For Alzheimer'S Disease Alzheimers & Dementia. 12: 253. DOI: 10.1016/J.Jalz.2016.06.453 |
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| 2016 |
Naj AC, Zhao Y, Lee SJvd, Hamilton KL, Kunkle BW, Partch AB, Valladares O, Beecham GW, Martin ER, Wang L, Haines JL, Mayeux R, Farrer LA, Pericak-Vance MA, Schellenberg GD. High-Resolution Imputation In Genome-Wide Association Studies Of Late-Onset Alzheimer'S Disease Identifies Novel Rare Variant Associations Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.308 |
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| 2016 |
Kunkle BW, Vardarajan BN, Naj AC, Cukier HN, Dykxhoorn DM, Rolati S, Whitehead PL, Carney RM, Cuccaro ML, Vance JM, Genetics Consortium AD, Farrer LA, Haines JL, Schellenberg GD, Martin ER, et al. O1-03-03: Identification of Novel Candidate Genes for Early-Onset Alzheimer's Disease Through Integrated Whole-Exome Sequencing and Exome Chip Array Association Analysis Alzheimer's & Dementia. 12: P177-P178. DOI: 10.1016/J.Jalz.2016.06.306 |
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| 2016 |
Marcora E, Renton AE, Beecham GW, Boerwinkle E, Cantwell L, Cruchaga C, Cweibel R, Felsenfeld A, Fornage M, Kapoor M, Kauwe K, Khaladkar M, Kobolt D, Ma Y, Mayeux R, ... ... Farrer LA, et al. F1-01-02: Alzheimer's Disease Sequencing Project: Search for Alzheimer's Disease Resilience Genes That May Modify Disease Susceptibility in Specific Apoe Genotype Backgrounds Alzheimer's & Dementia. 12: P162-P163. DOI: 10.1016/J.Jalz.2016.06.272 |
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| 2016 |
Jun GR, Chung J, Lunetta KL, Haines JL, Pericak-Vance MA, Mayeux R, Schellenberg GD, Farrer LA. Further Stratification Of Apoe E4-Negative Subjects Identifies Novel Genes For Alzheimer'S Disease Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.1290 |
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| 2016 |
Marcora E, Renton AE, Beecham GW, Boerwinkle E, Cantwell L, Cruchaga C, Cweibel R, Felsenfeld A, Fornage M, Kapoor M, Kauwe K, Khaladkar M, Kobolt D, Ma Y, Mayeux R, ... ... Farrer LA, et al. P2-077: Alzheimer's Disease Sequencing Project: Search for Alzheimer's Disease Resilience Genes That May Modify Disease Susceptibility in Specific Apoe
Genotype Backgrounds Alzheimer's & Dementia. 12: P638-P638. DOI: 10.1016/j.jalz.2016.06.1282 |
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| 2015 |
Polimanti R, Zhang H, Smith AH, Zhao H, Farrer LA, Kranzler HR, Gelernter J. Genome-wide association study of body mass index in subjects with alcohol dependence. Addiction Biology. PMID 26458734 DOI: 10.1111/adb.12317 |
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| 2015 |
Barral S, Cheng R, Reitz C, Vardarajan B, Lee J, Kunkle B, Beecham G, Cantwell LS, Pericak-Vance MA, Farrer LA, Haines JL, Goate AM, Foroud T, Boerwinkle E, Schellenberg GD, et al. Linkage analyses in Caribbean Hispanic families identify novel loci associated with familial late-onset Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26433351 DOI: 10.1016/J.Jalz.2015.07.487 |
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| 2015 |
Ghani M, Reitz C, Cheng R, Vardarajan BN, Jun G, Sato C, Naj A, Rajbhandary R, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, ... ... Farrer LA, et al. Association of Long Runs of Homozygosity With Alzheimer Disease Among African American Individuals. Jama Neurology. PMID 26366463 DOI: 10.1001/Jamaneurol.2015.1700 |
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| 2015 |
Kunkle BW, Jaworski J, Barral S, Vardarajan B, Beecham GW, Martin ER, Cantwell LS, Partch A, Bird TD, Raskind WH, DeStefano AL, Carney RM, Cuccaro M, Vance JM, Farrer LA, et al. Genome-wide linkage analyses of non-Hispanic white families identify novel loci for familial late-onset Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26365416 DOI: 10.1016/J.Jalz.2015.05.020 |
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| 2015 |
Tosto G, Fu H, Vardarajan BN, Lee JH, Cheng R, Reyes-Dumeyer D, Lantigua R, Medrano M, Jimenez-Velazquez IZ, Elkind MS, Wright CB, Sacco RL, Pericak-Vance M, Farrer L, Rogaeva E, et al. F-box/LRR-repeat protein 7 is genetically associated with Alzheimer's disease. Annals of Clinical and Translational Neurology. 2: 810-20. PMID 26339675 DOI: 10.1002/Acn3.223 |
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| 2015 |
Farrer LA. Expanding the genomic roadmap of Alzheimer's disease. The Lancet. Neurology. 14: 783-785. PMID 26141618 DOI: 10.1016/S1474-4422(15)00146-5 |
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| 2015 |
Hohman TJ, Cooke-Bailey JN, Reitz C, Jun G, Naj A, Beecham GW, Liu Z, Carney RM, Vance JM, Cuccaro ML, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, ... ... Farrer LA, et al. Global and local ancestry in African-Americans: Implications for Alzheimer's disease risk. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 26092349 DOI: 10.1016/J.Jalz.2015.02.012 |
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| 2015 |
Sulovari A, Kranzler HR, Farrer LA, Gelernter J, Li D. Eye color: A potential indicator of alcohol dependence risk in European Americans. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 168: 347-53. PMID 25921801 DOI: 10.1002/Ajmg.B.32316 |
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| 2015 |
Desikan RS, Schork AJ, Wang Y, Thompson WK, Dehghan A, Ridker PM, Chasman DI, McEvoy LK, Holland D, Chen CH, Karow DS, Brewer JB, Hess CP, Williams J, Sims R, ... ... Farrer LA, et al. Polygenic Overlap Between C-Reactive Protein, Plasma Lipids, and Alzheimer Disease. Circulation. 131: 2061-9. PMID 25862742 DOI: 10.1161/Circulationaha.115.015489 |
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| 2015 |
Hart AB, Lynch KG, Farrer L, Gelernter J, Kranzler HR. Which alcohol use disorder criteria contribute to the association of ADH1B with alcohol dependence? Addiction Biology. PMID 25828809 DOI: 10.1111/adb.12244 |
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Jun G, Ibrahim-Verbaas CA, Vronskaya M, Lambert JC, Chung J, Naj AC, Kunkle BW, Wang LS, Bis JC, Bellenguez C, Harold D, Lunetta KL, Destefano AL, Grenier-Boley B, Sims R, ... ... Farrer LA, et al. A novel Alzheimer disease locus located near the gene encoding tau protein. Molecular Psychiatry. PMID 25778476 DOI: 10.1038/Mp.2015.23 |
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| 2015 |
Desikan RS, Schork AJ, Wang Y, Witoelar A, Sharma M, McEvoy LK, Holland D, Brewer JB, Chen CH, Thompson WK, Harold D, Williams J, Owen MJ, O'Donovan MC, Pericak-Vance MA, ... ... Farrer LA, et al. Genetic overlap between Alzheimer's disease and Parkinson's disease at the MAPT locus. Molecular Psychiatry. PMID 25687773 DOI: 10.1038/Mp.2015.6 |
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| 2015 |
Inzelberg R, Massarwa M, Schechtman E, Strugatsky R, Farrer LA, Friedland RP. Estimating the risk for conversion from mild cognitive impairment to Alzheimer's disease in an elderly Arab community. Journal of Alzheimer's Disease : Jad. 45: 865-71. PMID 25624416 DOI: 10.3233/Jad-142871 |
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| 2015 |
Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, ... ... Farrer LA, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/Jamaneurol.2014.2157 |
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| 2015 |
Jun G, Chung J, Tosto G, Vardarajan B, Reitz C, Lunetta KL, Manly JJ, Byrd GS, Haines JL, Pericak-Vance MA, Kuwano R, Mayeux R, Schellenberg GD, Farrer LA. Transethnic genome-wide meta-analysis for Alzheimer disease Alzheimers & Dementia. 11: 230. DOI: 10.1016/J.Jalz.2015.07.266 |
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| 2015 |
Cukier HN, Kunkle BW, Rolati S, Hamilton-Nelson KL, Kohli MA, Dombroski BA, Vardarajan BN, Whitehead PL, Booven DJV, Martin ER, Beecham GW, Farrer LA, Cuccaro ML, Vance JM, Mayeux R, et al. ABCA7 deletion associated with Alzheimer's disease in african americans Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.06.549 |
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| 2014 |
Wetzel-Smith MK, Hunkapiller J, Bhangale TR, Srinivasan K, Maloney JA, Atwal JK, Sa SM, Yaylaoglu MB, Foreman O, Ortmann W, Rathore N, Hansen DV, Tessier-Lavigne M, Mayeux R, ... ... Farrer LA, et al. A rare mutation in UNC5C predisposes to late-onset Alzheimer's disease and increases neuronal cell death. Nature Medicine. 20: 1452-7. PMID 25419706 DOI: 10.1038/Nm.3736 |
0.338 |
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| 2014 |
Allen M, Kachadoorian M, Quicksall Z, Zou F, Chai HS, Younkin C, Crook JE, Pankratz VS, Carrasquillo MM, Krishnan S, Nguyen T, Ma L, Malphrus K, Lincoln S, Bisceglio G, ... ... Farrer LA, et al. Association of MAPT haplotypes with Alzheimer's disease risk and MAPT brain gene expression levels. Alzheimer's Research & Therapy. 6: 39. PMID 25324900 DOI: 10.1186/Alzrt268 |
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| 2014 |
Naj AC, Jun G, Reitz C, Kunkle BW, Perry W, Park YS, Beecham GW, Rajbhandary RA, Hamilton-Nelson KL, Wang LS, Kauwe JS, Huentelman MJ, Myers AJ, Bird TD, Boeve BF, ... ... Farrer LA, et al. Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study. Jama Neurology. 71: 1394-404. PMID 25199842 DOI: 10.1001/Jamaneurol.2014.1491 |
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| 2014 |
Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel JP, Younkin SG, Bennett DA, De Jager PL, Larson EB, Crane PK, Kamboh MI, ... ... Farrer LA, et al. Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. Plos Genetics. 10: e1004606. PMID 25188341 DOI: 10.1371/Journal.Pgen.1004606 |
0.456 |
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| 2014 |
Jun G, Asai H, Zeldich E, Drapeau E, Chen C, Chung J, Park JH, Kim S, Haroutunian V, Foroud T, Kuwano R, Haines JL, Pericak-Vance MA, Schellenberg GD, Lunetta KL, ... ... Farrer LA, et al. PLXNA4 is associated with Alzheimer disease and modulates tau phosphorylation. Annals of Neurology. 76: 379-92. PMID 25043464 DOI: 10.1002/Ana.24219 |
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| 2014 |
Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, ... ... Farrer LA, et al. Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease. Plos One. 9: e94661. PMID 24922517 DOI: 10.1371/Journal.Pone.0094661 |
0.377 |
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| 2014 |
Ratnapriya R, Zhan X, Fariss RN, Branham KE, Zipprer D, Chakarova CF, Sergeev YV, Campos MM, Othman M, Friedman JS, Maminishkis A, Waseem NH, Brooks M, Rajasimha HK, Edwards AO, ... ... Farrer LA, et al. Rare and common variants in extracellular matrix gene Fibrillin 2 (FBN2) are associated with macular degeneration. Human Molecular Genetics. 23: 5827-37. PMID 24899048 DOI: 10.1093/Hmg/Ddu276 |
0.312 |
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| 2014 |
Nelson PT, Estus S, Abner EL, Parikh I, Malik M, Neltner JH, Ighodaro E, Wang WX, Wilfred BR, Wang LS, Kukull WA, Nandakumar K, Farman ML, Poon WW, Corrada MM, ... ... Farrer LA, et al. ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology. Acta Neuropathologica. 127: 825-43. PMID 24770881 DOI: 10.1007/S00401-014-1282-2 |
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| 2014 |
Furman CD, Earnshaw LA, Doukas DJ, Farrer LA, Friedland RP. A case of inappropriate apolipoprotein e testing in Alzheimer's disease due to lack of an informed consent discussion. American Journal of Alzheimer's Disease and Other Dementias. 29: 590-5. PMID 24615498 DOI: 10.1177/1533317514525829 |
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| 2014 |
Ruiz A, Heilmann S, Becker T, Hernández I, Wagner H, Thelen M, Mauleón A, Rosende-Roca M, Bellenguez C, Bis JC, Harold D, Gerrish A, Sims R, Sotolongo-Grau O, Espinosa A, ... ... Farrer LA, et al. Follow-up of loci from the International Genomics of Alzheimer's Disease Project identifies TRIP4 as a novel susceptibility gene. Translational Psychiatry. 4: e358. PMID 24495969 DOI: 10.1038/Tp.2014.2 |
0.369 |
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| 2014 |
Benitez BA, Jin SC, Guerreiro R, Graham R, Lord J, Harold D, Sims R, Lambert JC, Gibbs JR, Bras J, Sassi C, Harari O, Bertelsen S, Lupton MK, Powell J, ... ... Farrer LA, et al. Missense variant in TREML2 protects against Alzheimer's disease. Neurobiology of Aging. 35: 1510.e19-26. PMID 24439484 DOI: 10.1016/J.Neurobiolaging.2013.12.010 |
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| 2014 |
Yang C, Li C, Kranzler HR, Farrer LA, Zhao H, Gelernter J. Exploring the genetic architecture of alcohol dependence in African-Americans via analysis of a genomewide set of common variants. Human Genetics. 133: 617-24. PMID 24297757 DOI: 10.1007/s00439-013-1399-8 |
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| 2014 |
Gelernter J, Kranzler HR, Sherva R, Almasy L, Koesterer R, Smith AH, Anton R, Preuss UW, Ridinger M, Rujescu D, Wodarz N, Zill P, Zhao H, Farrer LA. Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci. Molecular Psychiatry. 19: 41-9. PMID 24166409 DOI: 10.1038/Mp.2013.145 |
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| 2014 |
Shen L, Thompson PM, Potkin SG, Bertram L, Farrer LA, Foroud TM, Green RC, Hu X, Huentelman MJ, Kim S, Kauwe JS, Li Q, Liu E, Macciardi F, Moore JH, et al. Genetic analysis of quantitative phenotypes in AD and MCI: imaging, cognition and biomarkers. Brain Imaging and Behavior. 8: 183-207. PMID 24092460 DOI: 10.1007/S11682-013-9262-Z |
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| 2014 |
Sherva R, Tripodis Y, Bennett DA, Chibnik LB, Crane PK, de Jager PL, Farrer LA, Saykin AJ, Shulman JM, Naj A, Green RC. Genome-wide association study of the rate of cognitive decline in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 45-52. PMID 23535033 DOI: 10.1016/J.Jalz.2013.01.008 |
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| 2014 |
Pericak-Vance M, Reitz C, Kunkle BW, Vardarajan BN, Kohli MA, Naj AC, Whitehead PL, Perry W, Martin E, Beecham G, Gilbert J, Farrer LA, Haines J, Schellenberg GD, Mayeux R. P2-131: WHOLE-EXOME SEQUENCING OF HISPANIC EARLY-ONSET ALZHEIMER DISEASE FAMILIES IDENTIFIES RARE VARIANTS IN MULTIPLE ALZHEIMER'S-RELATED GENES Alzheimer's & Dementia. 10: P518-P519. DOI: 10.1016/J.Jalz.2014.05.806 |
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| 2014 |
Reitz C, Cheng R, Kunkle BW, Beecham G, Pericak-Vance MA, Farrer LA, Haines J, Schellenberg GD, Mayeux R. P1-054: LINKAGE ANALYSES OF EXTENDED CARIBBEAN HISPANIC FAMILIES INDICATES NOVEL LOCI ASSOCIATED WITH FAMILIAL LATE-ONSET ALZHEIMER'S DISEASE Alzheimer's & Dementia. 10: P323-P323. DOI: 10.1016/J.Jalz.2014.05.290 |
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| 2014 |
Chung J, Farrer LA, Jun G. P1-035: BIVARIATE GENOME-WIDE ASSOCIATION STUDY OF ALZHEIMER DISEASE ENDOPHENOTYPES IDENTIFIES NOVEL LOCI Alzheimer's & Dementia. 10: P316-P316. DOI: 10.1016/j.jalz.2014.05.270 |
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| 2014 |
Kunkle BW, Naj AC, Hamilton-Nelson K, Perry WR, Partch A, Valladares O, Chung J, Jun G, Schmidt M, Beecham G, Wang L, Martin E, Mayeux R, Haines J, Farrer LA, et al. Low-Frequency Variant Imputation Identifies Novel Disease-Associated Loci In A Genome-Wide Association Study Of Late-Onset Alzheimer'S Disease Alzheimers & Dementia. 10: 135. DOI: 10.1016/J.Jalz.2014.04.076 |
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| 2013 |
Logue MW, Schu M, Vardarajan BN, Farrell J, Lunetta KL, Jun G, Baldwin CT, Deangelis MM, Farrer LA. Search for age-related macular degeneration risk variants in Alzheimer disease genes and pathways. Neurobiology of Aging. 35: 1510.e7-18. PMID 24439028 DOI: 10.1016/j.neurobiolaging.2013.12.007 |
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| 2013 |
Han S, Yang BZ, Kranzler HR, Liu X, Zhao H, Farrer LA, Boerwinkle E, Potash JB, Gelernter J. Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence. American Journal of Human Genetics. 93: 1027-34. PMID 24268660 DOI: 10.1016/J.Ajhg.2013.10.021 |
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| 2013 |
Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, ... ... Farrer LA, et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nature Genetics. 45: 1452-8. PMID 24162737 DOI: 10.1038/Ng.2802 |
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| 2013 |
Schilling S, DeStefano AL, Sachdev PS, Choi SH, Mather KA, DeCarli CD, Wen W, Høgh P, Raz N, Au R, Beiser A, Wolf PA, Romero JR, Zhu YC, Lunetta KL, ... Farrer L, et al. APOE genotype and MRI markers of cerebrovascular disease: systematic review and meta-analysis. Neurology. 81: 292-300. PMID 23858411 DOI: 10.1212/Wnl.0B013E31829Bfda4 |
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| 2013 |
Nho K, Corneveaux JJ, Kim S, Lin H, Risacher SL, Shen L, Swaminathan S, Ramanan VK, Liu Y, Foroud T, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, ... ... Farrer LA, et al. Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment. Molecular Psychiatry. 18: 781-7. PMID 23608917 DOI: 10.1038/Mp.2013.24 |
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| 2013 |
Reitz C, Jun G, Naj A, Rajbhandary R, Vardarajan BN, Wang LS, Valladares O, Lin CF, Larson EB, Graff-Radford NR, Evans D, De Jager PL, Crane PK, Buxbaum JD, Murrell JR, ... ... Farrer LA, et al. Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E ϵ4,and the risk of late-onset Alzheimer disease in African Americans. Jama. 309: 1483-92. PMID 23571587 DOI: 10.1001/Jama.2013.2973 |
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| 2013 |
Miyashita A, Koike A, Jun G, Wang LS, Takahashi S, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, ... ... Farrer LA, et al. SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians. Plos One. 8: e58618. PMID 23565137 DOI: 10.1371/Journal.Pone.0058618 |
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| 2013 |
Cruchaga C, Kauwe JS, Harari O, Jin SC, Cai Y, Karch CM, Benitez BA, Jeng AT, Skorupa T, Carrell D, Bertelsen S, Bailey M, McKean D, Shulman JM, De Jager PL, ... ... Farrer LA, et al. GWAS of cerebrospinal fluid tau levels identifies risk variants for Alzheimer's disease. Neuron. 78: 256-68. PMID 23562540 DOI: 10.1016/J.Neuron.2013.02.026 |
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| 2013 |
Vardarajan B, Vergote D, Tissir F, Logue M, Yang J, Daude N, Ando K, Rogaeva E, Lee J, Cheng R, Brion JP, Ghani M, Shi B, Baldwin CT, Kar S, ... ... Farrer LA, et al. Role of p73 in Alzheimer disease: lack of association in mouse models or in human cohorts. Molecular Neurodegeneration. 8: 10. PMID 23414597 DOI: 10.1186/1750-1326-8-10 |
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| 2013 |
Holton P, Ryten M, Nalls M, Trabzuni D, Weale ME, Hernandez D, Crehan H, Gibbs JR, Mayeux R, Haines JL, Farrer LA, Pericak-Vance MA, Schellenberg GD, Ramirez-Restrepo M, et al. Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci. Annals of Human Genetics. 77: 85-105. PMID 23360175 DOI: 10.1111/Ahg.12000 |
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| 2013 |
Miyashita A, Koike A, Jun G, Wang L, Takahashi S, Matsubara E, Kawarabayashi T, Shoji M, Tomita N, Arai H, Asada T, Harigaya Y, Ikeda M, Amari M, Hanyu H, ... ... Farrer LA, et al. Correction: SORL1 Is Genetically Associated with Late-Onset Alzheimer’s Disease in Japanese, Koreans and Caucasians Plos One. 8. DOI: 10.1371/annotation/fcb56ea7-d32a-4e45-818d-39cef330c731 |
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| 2013 |
Martin E, Kunkle B, Haines J, Farrer L, Pericak-Vance M, Schellenberg G. ADGC+: An expanded Alzheimer's Disease Genetics Consortium (ADGC) genome-wide association study Alzheimers & Dementia. 9: 557. DOI: 10.1016/J.Jalz.2013.05.1089 |
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| 2013 |
Kuwano R, Miyashita A, Koike A, Jun G, Wang L, Takahashi S, Kim J, George-Hyslop PS, Mayeux R, Haines J, Pericak-Vance M, Yoshida M, Nishida N, Tokunaga K, Yamamoto K, ... ... Farrer L, et al. O4-06-05: SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians Alzheimer's & Dementia. 9: P693-P694. DOI: 10.1016/j.jalz.2013.04.369 |
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| 2013 |
Beecham G, Hamilton-Nelson K, Naj A, Wang L, Martin E, Mayeux R, Haines J, Farrer L, Schellenberg G, Pericak-Vance M, Montine T. O4-06-04: Late-onset Alzheimer's disease neuropathology genomic screen identifies novel loci for neuritic plaque and other Alzheimer's neuropathology features Alzheimer's & Dementia. 9: P693-P693. DOI: 10.1016/J.Jalz.2013.04.368 |
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| 2013 |
Jun G, Asai H, Drapeau E, Park J, Zeldich E, Chen C, Kim S, Foroud T, Lunetta K, Kim J, Buxbaum J, Abraham C, Ikezu T, Mayeux R, Farrer L. O4-06-02: Genetic variation in PLXNA4 associated with susceptibility of Alzheimer's disease through tau phosphorylation Alzheimer's & Dementia. 9: P692-P692. DOI: 10.1016/J.Jalz.2013.04.366 |
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| 2013 |
Farrer L. PL-04-02: The role of common and rare variants in risk for Alzheimer's disease across populations Alzheimer's & Dementia. 9: P677-P677. DOI: 10.1016/j.jalz.2013.04.333 |
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| 2013 |
Logue M, Schu M, Vardarajan B, Farrell J, Lunetta K, Baldwin C, Fallin D, Farrer L. O3-01-01: Two rare AKAP9 missense variants are associated with Alzheimer's disease in African-Americans Alzheimer's & Dementia. 9: P516-P517. DOI: 10.1016/j.jalz.2013.04.236 |
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| 2012 |
Friedland RP, Shah JJ, Farrer LA, Vardarajan B, Rebolledo-Mendez JD, Mok K, Hardy J. Behavioral variant frontotemporal lobar degeneration with amyotrophic lateral sclerosis with a chromosome 9p21 hexanucleotide repeat. Frontiers in Neurology. 3: 136. PMID 23060854 DOI: 10.3389/Fneur.2012.00136 |
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| 2012 |
Jun G, Moncaster JA, Koutras C, Seshadri S, Buros J, McKee AC, Levesque G, Wolf PA, St George-Hyslop P, Goldstein LE, Farrer LA. δ-Catenin is genetically and biologically associated with cortical cataract and future Alzheimer-related structural and functional brain changes. Plos One. 7: e43728. PMID 22984439 DOI: 10.1371/journal.pone.0043728 |
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| 2012 |
Jun G, Vardarajan BN, Buros J, Yu CE, Hawk MV, Dombroski BA, Crane PK, Larson EB, Mayeux R, Haines JL, Lunetta KL, Pericak-Vance MA, Schellenberg GD, Farrer LA. Comprehensive search for Alzheimer disease susceptibility loci in the APOE region. Archives of Neurology. 69: 1270-9. PMID 22869155 DOI: 10.1001/Archneurol.2012.2052 |
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Melville SA, Buros J, Parrado AR, Vardarajan B, Logue MW, Shen L, Risacher SL, Kim S, Jun G, DeCarli C, Lunetta KL, Baldwin CT, Saykin AJ, Farrer LA. Multiple loci influencing hippocampal degeneration identified by genome scan. Annals of Neurology. 72: 65-75. PMID 22745009 DOI: 10.1002/Ana.23644 |
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| 2012 |
Allen M, Zou F, Chai HS, Younkin CS, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, ... ... Farrer LA, et al. Novel late-onset Alzheimer disease loci variants associate with brain gene expression. Neurology. 79: 221-8. PMID 22722634 DOI: 10.1212/Wnl.0B013E3182605801 |
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Zou F, Chai HS, Younkin CS, Allen M, Crook J, Pankratz VS, Carrasquillo MM, Rowley CN, Nair AA, Middha S, Maharjan S, Nguyen T, Ma L, Malphrus KG, Palusak R, ... ... Farrer LA, et al. Brain expression genome-wide association study (eGWAS) identifies human disease-associated variants. Plos Genetics. 8: e1002707. PMID 22685416 DOI: 10.1371/Journal.Pgen.1002707 |
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Vardarajan BN, Bruesegem SY, Harbour ME, Inzelberg R, Friedland R, St George-Hyslop P, Seaman MN, Farrer LA. Identification of Alzheimer disease-associated variants in genes that regulate retromer function. Neurobiology of Aging. 33: 2231.e15-2231.e30. PMID 22673115 DOI: 10.1016/j.neurobiolaging.2012.04.020 |
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| 2012 |
Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, ... ... Farrer LA, et al. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Human Molecular Genetics. 21: 3500-12. PMID 22556362 DOI: 10.1093/Hmg/Dds161 |
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| 2012 |
Afgin AE, Massarwa M, Schechtman E, Israeli-Korn SD, Strugatsky R, Abuful A, Farrer LA, Friedland RP, Inzelberg R. High prevalence of mild cognitive impairment and Alzheimer's disease in arabic villages in northern Israel: impact of gender and education. Journal of Alzheimer's Disease : Jad. 29: 431-9. PMID 22233764 DOI: 10.3233/Jad-2011-111667 |
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| 2012 |
Erlich PM, Lunetta KL, Cupples LA, Abraham CR, Green RC, Baldwin CT, Farrer LA. Serum paraoxonase activity is associated with variants in the PON gene cluster and risk of Alzheimer disease. Neurobiology of Aging. 33: 1015.e7-23. PMID 20980077 DOI: 10.1016/J.Neurobiolaging.2010.08.003 |
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Afgin A, Massarwa M, Schechtman E, Israeli-Korn S, Strugatsky R, Abuful A, Farrer L, Friedland R, Inzelberg R. Conversion from Mild Cognitive Impairment to Alzheimer's Disease in an Elderly Arab Population (P01.088) Neurology. 78: P01.088-P01.088. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P01.088 |
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| 2012 |
Reitz C, Manly J, Hall KS, Evans D, Bennett D, Buxbaum J, Ertekin-Taner N, Fallin D, Kamboh I, Foroud T, Goate A, Farrer L, Pericak-Vance M, Haines J, Mayeux R, et al. CTNNA3, CAPRIN2 and SPG20 are significantly associated with Alzheimer's disease in preliminary analyses of a genome-wide association study in African-Americans Alzheimers & Dementia. 8: 100. DOI: 10.1016/J.Jalz.2012.05.251 |
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| 2012 |
Kuwano R, Miyashita A, Koike A, Nishida N, Tokunaga K, Yamamoto K, Ihara Y, Kim J, Pericak-Vance M, Farrer L, Schellenberg G. Genome-wide association study of Alzheimer's disease: A collaborative genetic study on Alzheimer's disease with Japan, Korea and the Alzheimer's Disease Genetics Consortium Alzheimers & Dementia. 8. DOI: 10.1016/J.Jalz.2012.05.2111 |
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| 2012 |
Beecham G, Montine T, Rajbhandary R, Hamilton-Nelson K, Naj A, Martin E, Mayeux R, Haines J, Farrer L, Schellenberg G, Pericak-Vance M. P4-102: APP associated with late-onset Alzheimer's disease in an autopsy-confirmed dataset Alzheimer's & Dementia. 8: P668-P668. DOI: 10.1016/J.Jalz.2012.05.1805 |
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Vardarajan BN, Bruesegem S, Harbour M, St. George-Hyslop P, Seaman M, Farrer L. P4-089: Candidate gene study in the endosome-to-Golgi retrieval pathway reveals association of retromer genes with Alzheimer's disease Alzheimer's & Dementia. 8: P664-P664. DOI: 10.1016/j.jalz.2012.05.1791 |
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| 2011 |
Logue MW, Schu M, Vardarajan BN, Buros J, Green RC, Go RC, Griffith P, Obisesan TO, Shatz R, Borenstein A, Cupples LA, Lunetta KL, Fallin MD, Baldwin CT, Farrer LA, et al. A comprehensive genetic association study of Alzheimer disease in African Americans. Archives of Neurology. 68: 1569-79. PMID 22159054 DOI: 10.1001/Archneurol.2011.646 |
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| 2011 |
Reitz C, Rogaeva E, Foroud T, Farrer LA. Genetics and genomics of late-onset Alzheimer's disease and its endophenotypes. International Journal of Alzheimer's Disease. 2011: 284728. PMID 21660206 DOI: 10.4061/2011/284728 |
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| 2011 |
Sherva R, Farrer LA. Power and pitfalls of the genome-wide association study approach to identify genes for Alzheimer's disease. Current Psychiatry Reports. 13: 138-46. PMID 21312009 DOI: 10.1007/S11920-011-0184-4 |
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| 2011 |
Reitz C, Tokuhiro S, Clark LN, Conrad C, Vonsattel JP, Hazrati LN, Palotás A, Lantigua R, Medrano M, Z Jiménez-Velázquez I, Vardarajan B, Simkin I, Haines JL, Pericak-Vance MA, Farrer LA, et al. SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk. Annals of Neurology. 69: 47-64. PMID 21280075 DOI: 10.1002/Ana.22308 |
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| 2011 |
Reitz C, Cheng R, Rogaeva E, Lee JH, Tokuhiro S, Zou F, Bettens K, Sleegers K, Tan EK, Kimura R, Shibata N, Arai H, Kamboh MI, Prince JA, Maier W, ... ... Farrer LA, et al. Meta-analysis of the association between variants in SORL1 and Alzheimer disease. Archives of Neurology. 68: 99-106. PMID 21220680 DOI: 10.1001/Archneurol.2010.346 |
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Sherva R, Baldwin CT, Inzelberg R, Vardarajan B, Cupples LA, Lunetta K, Bowirrat A, Naj A, Pericak-Vance M, Friedland RP, Farrer LA. Identification of novel candidate genes for Alzheimer's disease by autozygosity mapping using genome wide SNP data. Journal of Alzheimer's Disease : Jad. 23: 349-59. PMID 21098978 DOI: 10.3233/Jad-2010-100714 |
0.456 |
|
| 2011 |
Cuenco KT, Friedland R, Baldwin CT, Guo J, Vardarajan B, Lunetta KL, Cupples LA, Green RC, DeCarli C, Farrer LA. Association of TTR polymorphisms with hippocampal atrophy in Alzheimer disease families. Neurobiology of Aging. 32: 249-56. PMID 19328595 DOI: 10.1016/J.Neurobiolaging.2009.02.014 |
0.451 |
|
| 2011 |
Reitz C, Rogaeva E, Foroud T, Farrer LA. Genetics and genomics of late-onset Alzheimer's disease and its endophenotypes International Journal of Alzheimer's Disease. DOI: 10.4061/2011/284728 |
0.347 |
|
| 2011 |
Naj A, Jun G, Buros J, Gallins P, Farrer L, Haines J, Pericak-Vance M, Schellenberg G. Genome-Wide Association Study of Late-Onset Alzheimer Disease Identifies Disease-Associated Variants in MS4A4/MS4A6E, CD2AP, CD33, and EPHA1 Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.530 |
0.332 |
|
| 2010 |
Jun G, Naj AC, Beecham GW, Wang LS, Buros J, Gallins PJ, Buxbaum JD, Ertekin-Taner N, Fallin MD, Friedland R, Inzelberg R, Kramer P, Rogaeva E, St George-Hyslop P, ... ... Farrer LA, et al. Meta-analysis confirms CR1, CLU, and PICALM as alzheimer disease risk loci and reveals interactions with APOE genotypes. Archives of Neurology. 67: 1473-84. PMID 20697030 DOI: 10.1001/Archneurol.2010.201 |
0.424 |
|
| 2010 |
Seshadri S, Fitzpatrick AL, Ikram MA, DeStefano AL, Gudnason V, Boada M, Bis JC, Smith AV, Carassquillo MM, Lambert JC, Harold D, Schrijvers EM, Ramirez-Lorca R, Debette S, Longstreth WT, ... ... Farrer LA, et al. Genome-wide analysis of genetic loci associated with Alzheimer disease. Jama. 303: 1832-40. PMID 20460622 DOI: 10.1001/Jama.2010.574 |
0.457 |
|
| 2010 |
Saykin AJ, Shen L, Foroud TM, Potkin SG, Swaminathan S, Kim S, Risacher SL, Nho K, Huentelman MJ, Craig DW, Thompson PM, Stein JL, Moore JH, Farrer LA, Green RC, et al. Alzheimer's Disease Neuroimaging Initiative biomarkers as quantitative phenotypes: Genetics core aims, progress, and plans. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 6: 265-73. PMID 20451875 DOI: 10.1016/J.Jalz.2010.03.013 |
0.333 |
|
| 2010 |
Parrado AR, Logue M, Lunetta KL, Cupples A, DeCarli C, Baldwin CT, Farrer LA. Genome-wide Association of Cerebrovascular and Neurodegenerative Quantitative MRI Traits in Alzheimer's Disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.08.213 |
0.343 |
|
| 2010 |
Reitz C, Tokuhiro S, Clark L, Conrad C, Vonsattel J, Lantigua R, Medrano M, Simkin I, Haines J, Pericak-Vance M, Farrer L, Lee J, Rogaeva E, George-Hyslop PS, Mayeux R. Sorcs1 Alters APP Processing and Variants may Increase Alzheimer's Disease Risk Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.08.091 |
0.348 |
|
| 2010 |
Vardarajan BN, Logue M, Cupples A, Lunetta K, Jun G, Buros J, Seaman M, Baldwin C, Farrer L. P1-070: Candidate gene study in the endosome-to-Golgi retrieval pathway reveals association of retromer genes with Alzheimer's disease Alzheimer's & Dementia. 6: S194-S194. DOI: 10.1016/j.jalz.2010.05.618 |
0.301 |
|
| 2010 |
Reitz C, Cheng R, Rogaeva E, Lee J, Tokuhiro S, Bettens K, Sleegers K, Tan EK, Kimura R, Shibata N, Kamboh IM, Prince J, Maier W, Riemenschneider M, Owen M, ... ... Farrer LA, et al. Meta-analysis of the association between SORL1 variants and Alzheimer's disease Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.351 |
0.399 |
|
| 2009 |
Cuenco KT, Green RC, Zhang J, Lunetta K, Erlich PM, Cupples LA, Farrer LA, DeCarli C. Magnetic resonance imaging traits in siblings discordant for Alzheimer disease. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. 18: 268-75. PMID 18808654 DOI: 10.1111/J.1552-6569.2007.00191.X |
0.357 |
|
| 2008 |
T Cuenco K, Lunetta KL, Baldwin CT, McKee AC, Guo J, Cupples LA, Green RC, St George-Hyslop PH, Chui H, DeCarli C, Farrer LA. Association of distinct variants in SORL1 with cerebrovascular and neurodegenerative changes related to Alzheimer disease. Archives of Neurology. 65: 1640-8. PMID 19064752 DOI: 10.1001/Archneur.65.12.1640 |
0.389 |
|
| 2008 |
Lee JH, Cheng R, Rogaeva E, Meng Y, Stern Y, Santana V, Lantigua R, Medrano M, Jimenez-Velazquez IZ, Farrer LA, St George-Hyslop P, Mayeux R. Further examination of the candidate genes in chromosome 12p13 locus for late-onset Alzheimer disease. Neurogenetics. 9: 127-38. PMID 18340469 DOI: 10.1007/S10048-008-0122-8 |
0.374 |
|
| 2008 |
Sebastiani P, Timofeev N, Hartley SH, Dworkis D, Farrer L, Baldwin CT, Perls TT, Steinberg MH. Genome-Wide Association Studies Suggest Shared Polymorphisms Are Associated with Severity of Sickle Cell Anemia and Exceptional Longevity. Blood. 112: 1446-1446. DOI: 10.1182/Blood.V112.11.1446.1446 |
0.33 |
|
| 2008 |
Lukiw WJ, Riazanskaya N, Grigorenko A, Korovaitseva G, Dvoryanchikov G, Molyaka Y, Nicolaou M, Farrer L, Bazan NG, Rogaev EI. DNA polymorphism in the human presenilin-2 promoter: altered gene activity and potential contribution to the risk for AD Journal of Neurochemistry. 81: 76-76. DOI: 10.1046/J.1471-4159.81.S1.44_2.X |
0.376 |
|
| 2008 |
Farrer LA, Cuenco KT, Lunetta K, Baldwin CT, McKee AC, Guo J, Cupples LA, Green RC, St. George-Hyslop PH, Chui H, DeCarli C. O2-06-08: Distinct variants in SORL1 are associated with cerebrovascular and neurodegenerative changes related to Alzheimer's disease Alzheimer's & Dementia. 4: T145-T146. DOI: 10.1016/J.Jalz.2008.05.356 |
0.341 |
|
| 2008 |
Rogaeva E, Lee JH, Meng Y, Wakutani Y, Zou F, Moreno D, Cheng R, Sorbi S, Bruni A, Duara R, Graff-Radford N, Petersen RC, Dickson D, Younkin S, Farrer LA, et al. P3-258: Further evidence of genetic association between SORL1 and Alzheimer's disease Alzheimers & Dementia. 4. DOI: 10.1016/J.Jalz.2008.05.1826 |
0.378 |
|
| 2007 |
Meng Y, Lee JH, Cheng R, St George-Hyslop P, Mayeux R, Farrer LA. Association between SORL1 and Alzheimer's disease in a genome-wide study. Neuroreport. 18: 1761-4. PMID 18090307 DOI: 10.1097/WNR.0b013e3282f13e7a |
0.45 |
|
| 2007 |
Lunetta KL, Erlich PM, Cuenco KT, Cupples LA, Green RC, Farrer LA, Decarli C. Heritability of magnetic resonance imaging (MRI) traits in Alzheimer disease cases and their siblings in the MIRAGE study. Alzheimer Disease and Associated Disorders. 21: 85-91. PMID 17545732 DOI: 10.1097/Wad.0B013E3180653Bf7 |
0.366 |
|
| 2007 |
Faison WE, Schultz SK, Aerssens J, Alvidrez J, Anand R, Farrer LA, Jarvik L, Manly J, McRae T, Murphy GM, Olin JT, Regier D, Sano M, Mintzer JE. Potential ethnic modifiers in the assessment and treatment of Alzheimer's disease: challenges for the future. International Psychogeriatrics / Ipa. 19: 539-58. PMID 17451614 DOI: 10.1017/S104161020700511X |
0.356 |
|
| 2007 |
Lee JH, Cheng R, Schupf N, Manly J, Lantigua R, Stern Y, Rogaeva E, Wakutani Y, Farrer L, St George-Hyslop P, Mayeux R. The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort. Archives of Neurology. 64: 501-6. PMID 17420311 DOI: 10.1001/Archneur.64.4.501 |
0.439 |
|
| 2007 |
Rogaeva E, Meng Y, Lee JH, Gu Y, Kawarai T, Zou F, Katayama T, Baldwin CT, Cheng R, Hasegawa H, Chen F, Shibata N, Lunetta KL, Pardossi-Piquard R, Bohm C, ... ... Farrer LA, et al. The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease. Nature Genetics. 39: 168-77. PMID 17220890 DOI: 10.1038/Ng1943 |
0.358 |
|
| 2007 |
Shibata N, Kawarai T, Meng Y, Lee JH, Lee HS, Wakutani Y, Shibata E, Pathan N, Bi A, Sato C, Sorbi S, Bruni AC, Duara R, Mayeux R, Farrer LA, et al. Association studies between the plasmin genes and late-onset Alzheimer's disease. Neurobiology of Aging. 28: 1041-3. PMID 16828203 DOI: 10.1016/J.Neurobiolaging.2006.05.028 |
0.469 |
|
| 2006 |
Green RC, McNagny SE, Jayakumar P, Cupples LA, Benke K, Farrer LA. Statin use and the risk of Alzheimer's disease: the MIRAGE study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 2: 96-103. PMID 19595865 DOI: 10.1016/J.Jalz.2006.02.003 |
0.443 |
|
| 2006 |
Akomolafe A, Beiser A, Meigs JB, Au R, Green RC, Farrer LA, Wolf PA, Seshadri S. Diabetes mellitus and risk of developing Alzheimer disease: results from the Framingham Study. Archives of Neurology. 63: 1551-5. PMID 17101823 DOI: 10.1001/Archneur.63.11.1551 |
0.311 |
|
| 2006 |
Akomolafe A, Lunetta KL, Erlich PM, Cupples LA, Baldwin CT, Huyck M, Green RC, Farrer LA, Auerbach S, Griffith P, Ofili E, Browndyke J, Schmechel D, Welsh-Bohmer K, Chui H, et al. Genetic association between endothelial nitric oxide synthase and Alzheimer disease Clinical Genetics. 70: 49-56. PMID 16813604 DOI: 10.1111/J.1399-0004.2006.00638.X |
0.465 |
|
| 2006 |
Meng Y, Baldwin CT, Bowirrat A, Waraska K, Inzelberg R, Friedland RP, Farrer LA. Association of polymorphisms in the Angiotensin-converting enzyme gene with Alzheimer disease in an Israeli Arab community. American Journal of Human Genetics. 78: 871-7. PMID 16642441 DOI: 10.1086/503687 |
0.37 |
|
| 2006 |
Erlich PM, Lunetta KL, Cupples LA, Huyck M, Green RC, Baldwin CT, Farrer LA, Auerbach S, Akomolafe A, Griffith P, Ofili E, Browndyke J, Schmechel D, Welsh-Bohmer K, Chui H, et al. Polymorphisms in the PON gene cluster are associated with Alzheimer disease Human Molecular Genetics. 15: 77-85. PMID 16319130 DOI: 10.1093/Hmg/Ddi428 |
0.424 |
|
| 2006 |
Rogaeva E, Goto J, Takahashi Y, Seki N, Wakutani Y, Meng Y, Lee J, Erlich P, Cheng R, Lee H, Sato C, Mayeux R, Farrer LA, George-Hyslop PS, Tsuji S. P3-171: Genetic analysis of LRRK2 in parkinson disease and Alzheimer disease datasets Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.1439 |
0.324 |
|
| 2006 |
Lunetta KL, Erlich PM, Go RC, Friedland RP, Duara R, Kurz A, Dessa Sadovnick A, Akomolafe A, Chui H, Petrovitch H, Tsolaki M, Obisesan TO, Sabbagh MN, Farlow M, Relkin NR, ... ... Farrer LA, et al. P3-165: MRI traits are heritable among Alzheimer disease cases and their siblings in the MIRAGE Study Alzheimer's & Dementia. 2: S422-S423. DOI: 10.1016/J.Jalz.2006.05.1433 |
0.301 |
|
| 2005 |
Yip AG, McKee AC, Green RC, Wells J, Young H, Cupples LA, Farrer LA. APOE, vascular pathology, and the AD brain. Neurology. 65: 259-65. PMID 16043796 DOI: 10.1212/01.Wnl.0000168863.49053.4D |
0.408 |
|
| 2005 |
Yip AG, Green RC, Huyck M, Cupples LA, Farrer LA. Nonsteroidal anti-inflammatory drug use and Alzheimer's disease risk: the MIRAGE Study. Bmc Geriatrics. 5: 2. PMID 15647106 DOI: 10.1186/1471-2318-5-2 |
0.327 |
|
| 2005 |
Henderson VW, Benke KS, Green RC, Cupples LA, Farrer LA. Postmenopausal hormone therapy and Alzheimer's disease risk: interaction with age. Journal of Neurology, Neurosurgery, and Psychiatry. 76: 103-5. PMID 15608005 DOI: 10.1136/jnnp.2003.024927 |
0.322 |
|
| 2005 |
Sebastiani P, Baldwin CT, Nolan V, Wyszynski DF, Ma Q, Farrell J, Bisbee A, Waraska K, Farrer LA, Steinberg MH. Polymorphisms (Snps) in Multiple Genes of the Tgf-ß/Bmp Pathway Are Associated with a Global Measure of Sickle Cell Disease Severity. Blood. 106: 74-74. DOI: 10.1182/Blood.V106.11.74.74 |
0.302 |
|
| 2004 |
Rogaeva E, Meng Y, Toulina A, Shibata N, Kawarai T, Sato C, Salehi-Rad S, Morgan A, Rivoiro C, Liang Y, Sorbi S, Bruni AC, Oene MV, Lee J, Mayeux R, ... Farrer LA, et al. S2-01-03 Genetic studies in late-onset Alzheimer disease: loci on chromosomes 12 and 10 Neurobiology of Aging. 25. DOI: 10.1016/S0197-4580(04)80081-2 |
0.33 |
|
| 2003 |
Farrer LA, Friedland RP, Bowirrat A, Waraska K, Korczyn A, Baldwin CT. Genetic and environmental epidemiology of Alzheimer's disease in arabs residing in Israel. Journal of Molecular Neuroscience : Mn. 20: 207-12. PMID 14500999 DOI: 10.1385/Jmn:20:3:207 |
0.453 |
|
| 2003 |
Roberts JS, LaRusse SA, Katzen H, Whitehouse PJ, Barber M, Post SG, Relkin N, Quaid K, Pietrzak RH, Cupples LA, Farrer LA, Brown T, Green RC. Reasons for seeking genetic susceptibility testing among first-degree relatives of people with Alzheimer disease. Alzheimer Disease and Associated Disorders. 17: 86-93. PMID 12794385 DOI: 10.1097/00002093-200304000-00006 |
0.315 |
|
| 2002 |
Graff-Radford NR, Green RC, Go RC, Hutton ML, Edeki T, Bachman D, Adamson JL, Griffith P, Willis FB, Williams M, Hipps Y, Haines JL, Cupples LA, Farrer LA. Association between apolipoprotein E genotype and Alzheimer disease in African American subjects. Archives of Neurology. 59: 594-600. PMID 11939894 DOI: 10.1001/ARCHNEUR.59.4.594 |
0.404 |
|
| 2002 |
Green RC, Cupples LA, Go R, Benke KS, Edeki T, Griffith PA, Williams M, Hipps Y, Graff-Radford N, Bachman D, Farrer LA. Risk of dementia among white and African American relatives of patients with Alzheimer disease. Jama. 287: 329-36. PMID 11790212 |
0.426 |
|
| 2001 |
Nicolaou M, Song YQ, Sato CA, Orlacchio A, Kawarai T, Medeiros H, Liang Y, Sorbi S, Richard E, Rogaev EI, Moliaka Y, Bruni AC, Jorge R, Percy M, Duara R, ... Farrer LA, et al. Mutations in the open reading frame of the beta-site APP cleaving enzyme (BACE) locus are not a common cause of Alzheimer's disease. Neurogenetics. 3: 203-6. PMID 11714100 DOI: 10.1007/S100480100123 |
0.411 |
|
| 2001 |
Ishii K, Lippa C, Tomiyama T, Miyatake F, Ozawa K, Tamaoka A, Hasegawa T, Fraser PE, Shoji S, Nee LE, Pollen DA, St George-Hyslop PH, Ii K, Ohtake T, Kalaria RN, ... ... Farrer LA, et al. Distinguishable effects of presenilin-1 and APP717 mutations on amyloid plaque deposition. Neurobiology of Aging. 22: 367-76. PMID 11378241 DOI: 10.1016/S0197-4580(01)00216-0 |
0.32 |
|
| 2001 |
Farrer LA. Intercontinental epidemiology of Alzheimer disease: a global approach to bad gene hunting. Jama. 285: 796-8. PMID 11176918 DOI: 10.1001/JAMA.285.6.796 |
0.307 |
|
| 2000 |
Farrer LA, Sherbatich T, Keryanov SA, Korovaitseva GI, Rogaeva EA, Petruk S, Premkumar S, Moliaka Y, Song YQ, Pei Y, Sato C, Selezneva ND, Voskresenskaya S, Golimbet V, Sorbi S, et al. Association between angiotensin-converting enzyme and Alzheimer disease. Archives of Neurology. 57: 210-4. PMID 10681079 DOI: 10.1001/Archneur.57.2.210 |
0.331 |
|
| 2000 |
Farrer LA. Familial risk for Alzheimer disease in ethnic minorities: nondiscriminating genes. Archives of Neurology. 57: 28-9. PMID 10634429 DOI: 10.1001/ARCHNEUR.57.1.28 |
0.31 |
|
| 2000 |
Korovaitseva GI, Premkumar S, Grigorenko A, Molyaka Y, Galimbet V, Selezneva N, Gavrilova SI, Farrer LA, Rogaev EI. Alpha-2 macroglobulin gene in early- and late-onset Alzheimer disease. Neuroscience Letters. 271: 129-31. PMID 10477119 DOI: 10.1016/S0304-3940(99)00537-6 |
0.434 |
|
| 2000 |
Farrer LA. Candidate genes associated with Alzheimer's disease Neurobiology of Aging. 21: 138. DOI: 10.1016/S0197-4580(00)82418-5 |
0.373 |
|
| 2000 |
Farrer LA, Baldwin C, Korczyn A, Bowirrat A, Friedland RP. Genetic linkage studies of Alzheimer's disease in Israeli arabs Neurobiology of Aging. 21: 128. DOI: 10.1016/S0197-4580(00)82377-5 |
0.371 |
|
| 1999 |
Rogaeva EA, Premkumar S, Grubber J, Serneels L, Scott WK, Kawarai T, Song Y, Hill DL, Abou-Donia SM, Martin ER, Vance JJ, Yu G, Orlacchio A, Pei Y, Nishimura M, ... ... Farrer LA, et al. An alpha-2-macroglobulin insertion-deletion polymorphism in Alzheimer disease. Nature Genetics. 22: 19-22. PMID 10319855 DOI: 10.1038/8729 |
0.407 |
|
| 1998 |
Scott WK, Yamaoka LH, Bass MP, Gaskell PC, Conneally PM, Small GW, Farrer LA, Auerbach SA, Saunders AM, Roses AD, Haines JL, Pericak-Vance MA. No genetic association between the LRP receptor and sporadic or late-onset familial Alzheimer disease. Neurogenetics. 1: 179-83. PMID 10737120 DOI: 10.1007/S100480050026 |
0.466 |
|
| 1998 |
Farrer LA, Abraham CR, Haines JL, Rogaeva EA, Song Y, McGraw WT, Brindle N, Premkumar S, Scott WK, Yamaoka LH, Saunders AM, Roses AD, Auerbach SA, Sorbi S, Duara R, et al. Association between bleomycin hydrolase and Alzheimer's disease in caucasians. Annals of Neurology. 44: 808-11. PMID 9818937 DOI: 10.1002/Ana.410440515 |
0.632 |
|
| 1998 |
Rogaeva E, Premkumar S, Song Y, Sorbi S, Brindle N, Paterson A, Duara R, Levesque G, Yu G, Nishimura M, Ikeda M, O'Toole C, Kawarai T, Jorge R, Vilarino D, ... ... Farrer LA, et al. Evidence for an Alzheimer disease susceptibility locus on chromosome 12 and for further locus heterogeneity. Jama. 280: 614-8. PMID 9718052 DOI: 10.1001/Jama.280.7.614 |
0.339 |
|
| 1998 |
Song YQ, Rogaeva E, Premkumar S, Brindle N, Kawarai T, Orlacchio A, Yu G, Levesque G, Nishimura M, Ikeda M, Pei Y, O'Toole C, Duara R, Barker W, Sorbi S, ... ... Farrer L, et al. Absence of association between Alzheimer disease and the -491 regulatory region polymorphism of APOE. Neuroscience Letters. 250: 189-92. PMID 9708864 DOI: 10.1016/S0304-3940(98)00470-4 |
0.436 |
|
| 1998 |
Brindle N, Song Y, Rogaeva E, Premkumar S, Levesque G, Yu G, Ikeda M, Nishimura M, Paterson A, Sorbi S, Duara R, Farrer L, St George-Hyslop P. Analysis of the butyrylcholinesterase gene and nearby chromosome 3 markers in Alzheimer disease. Human Molecular Genetics. 7: 933-5. PMID 9536099 DOI: 10.1093/Hmg/7.5.933 |
0.394 |
|
| 1998 |
Farrer LA, Cupples LA, Myers RH, van Duijn CM, Mayeux R, Haines JL, Kukull WA, Hyman B, Pericak-Vance MA, Risch N. Effects of Age and Ethnicity on the Link Between APOE ϵ4 and Alzheimer Disease—Reply Jama. 279: 581. DOI: 10.1001/Jama.279.8.581A |
0.302 |
|
| 1997 |
Korovaitseva GI, Bukina A, Farrer LA, Rogaev EI. Presenilin polymorphisms in Alzheimer's disease. Lancet (London, England). 350: 959. PMID 9314893 DOI: 10.1016/S0140-6736(05)63300-4 |
0.397 |
|
| 1997 |
Scott WK, Saunders AM, Gaskell PC, Locke PA, Growdon JH, Farrer LA, Auerbach SA, Roses AD, Haines JL, Pericak-Vance MA. Apolipoprotein E epsilon2 does not increase risk of early-onset sporadic Alzheimer's disease. Annals of Neurology. 42: 376-8. PMID 9307262 DOI: 10.1002/Ana.410420317 |
0.417 |
|
| 1997 |
Scott WK, Yamaoka LH, Locke PA, Rosi BL, Gaskell PC, Saunders AM, Conneally PM, Small GW, Farrer LA, Growdon JH, Roses AD, Pericak-Vance MA, Haines JL. No association or linkage between an intronic polymorphism of presenilin-1 and sporadic or late-onset familial Alzheimer disease. Genetic Epidemiology. 14: 307-15. PMID 9181359 DOI: 10.1002/(Sici)1098-2272(1997)14:3<307::Aid-Gepi8>3.0.Co;2-1 |
0.462 |
|
| 1997 |
Post SG, Whitehouse PJ, Binstock RH, Bird TD, Eckert SK, Farrer LA, Fleck LM, Gaines AD, Juengst ET, Karlinsky H, Miles S, Murray TH, Quaid KA, Relkin NR, Roses AD, et al. The clinical introduction of genetic testing for Alzheimer disease. An ethical perspective. Jama. 277: 832-6. PMID 9052715 DOI: 10.1001/Jama.1997.03540340066035 |
0.343 |
|
| 1997 |
Farrer LA. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium Jama: the Journal of the American Medical Association. 278: 1349-1356. DOI: 10.1001/Jama.278.16.1349 |
0.404 |
|
| 1997 |
Farrer LA. Effects of Age, Sex, and Ethnicity on the Association Between Apolipoprotein E Genotype and Alzheimer Disease Jama. 278: 1349. DOI: 10.1001/Jama.1997.03550160069041 |
0.398 |
|
| 1996 |
Haines JL, Pritchard ML, Saunders AM, Schildkraut JM, Growdon JH, Gaskell PC, Farrer LA, Auerbach SA, Gusella JF, Locke PA, Rosi BL, Yamaoka L, Small GW, Conneally PM, Roses AD, et al. No association between alpha 1-antichymotrypsin and familial Alzheimer's disease. Annals of the New York Academy of Sciences. 802: 35-41. PMID 8993482 DOI: 10.1111/J.1749-6632.1996.Tb32596.X |
0.441 |
|
| 1996 |
Lautenschlager NT, Cupples LA, Rao VS, Auerbach SA, Becker R, Burke J, Chui H, Duara R, Foley EJ, Glatt SL, Green RC, Jones R, Karlinsky H, Kukull WA, Kurz A, ... ... Farrer LA, et al. Risk of dementia among relatives of Alzheimer's disease patients in the MIRAGE study: What is in store for the oldest old? Neurology. 46: 641-50. PMID 8618660 DOI: 10.1212/Wnl.46.3.641 |
0.354 |
|
| 1996 |
Haines JL, Pritchard ML, Saunders AM, Schildkraut JM, Growdon JH, Gaskell PC, Farrer LA, Auerbach SA, Gusella JF, Locke PA, Rosi BL, Yamaoka L, Small GW, Conneally PM, Roses AD, et al. No genetic effect of alpha1-antichymotrypsin in Alzheimer disease. Genomics. 33: 53-6. PMID 8617509 DOI: 10.1006/Geno.1996.0158 |
0.459 |
|
| 1996 |
Cupples LA, Duijn CMv, Kurz A, Green R, Chui H, Duara R, Auerbach S, Volicer L, Wells J, Broeckhoven Cv, Growdon JH, Haines JL, Farrer LA. 749 Evidence for major gene inheritance of Alzheimer disease in families of patients with and without APOE ε4. VS Rao Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80751-2 |
0.331 |
|
| 1996 |
Scott WK, Yamoakal L, Locke PA, Rosil B, Gaskelll PC, Saundersl AM, Conneally PM, Small G, Farrer L, Growden JH, Rosesl AD, Haines JL, Pericak-Vancel MA. 52 No association or linkage between the BamH1 polymorphism of the presenilin-I gene and late-onset Alzheimer disease Neurobiology of Aging. 17. DOI: 10.1016/S0197-4580(96)80054-6 |
0.418 |
|
| 1995 |
Farrer LA, Cupples LA, van Duijn CM, Connor-Lacke L, Kiely DK, Growdon JH. Rate of progression of Alzheimer's disease is associated with genetic risk. Archives of Neurology. 52: 918-23. PMID 7661731 DOI: 10.1001/archneur.1995.00540330100021 |
0.387 |
|
| 1995 |
Farrer LA, Abraham CR, Volicer L, Foley EJ, Kowall NW, McKee AC, Wells JM. Allele epsilon 4 of apolipoprotein E shows a dose effect on age at onset of Pick disease. Experimental Neurology. 136: 162-70. PMID 7498406 DOI: 10.1006/Exnr.1995.1093 |
0.624 |
|
| 1995 |
Farrer LA, Cupples LA, Van Duijn CM, Kurz A, Zimmer R, Müller U, Green RC, Clarke V, Shoffner J, Wallace DC, Chui H, Flanagan SD, Duara R, St. George-Hyslop P, Auerbach SA, et al. Apolipoprotein E genotype in patients with Alzheimer's disease: Implications for the risk of dementia among relatives Annals of Neurology. 38: 797-808. PMID 7486872 DOI: 10.1002/Ana.410380515 |
0.389 |
|
| 1995 |
Farrer LA. Statement on Use of Apolipoprotein E Testing for Alzheimer Disease Jama: the Journal of the American Medical Association. 274: 1627. DOI: 10.1001/Jama.1995.03530200063039 |
0.384 |
|
| 1994 |
Farrer LA, Cupples LA, Blackburn S, Kiely DK, Auerbach S, Growdon JH, Connor-Lacke L, Karlinsky H, Thibert A, Burke JR. Interrater agreement for diagnosis of Alzheimer's disease: the MIRAGE study. Neurology. 44: 652-6. PMID 8164819 DOI: 10.1212/Wnl.44.4.652 |
0.365 |
|
| 1993 |
van Duijn CM, Farrer LA, Cupples LA, Hofman A. Genetic transmission of Alzheimer's disease among families in a Dutch population based study. Journal of Medical Genetics. 30: 640-6. PMID 8411049 DOI: 10.1136/jmg.30.8.640 |
0.389 |
|
| 1993 |
Karlinsky H, Berg JM, Lennox A, Ray PN, St George-Hyslop P, Farrer LA, Percy ME, Andrews DF, Atack EA. Monozygotic twins concordant for late-onset probable Alzheimer disease with suspected Alzheimer disease in four sibs. American Journal of Medical Genetics. 44: 591-7. PMID 1481815 DOI: 10.1002/ajmg.1320440512 |
0.403 |
|
| 1992 |
St George-Hyslop P, Haines J, Rogaev E, Mortilla M, Vaula G, Pericak-Vance M, Foncin JF, Montesi M, Bruni A, Sorbi S, Rainero I, Pinessi L, Pollen D, Polinsky R, Nee L, ... ... Farrer L, et al. Genetic evidence for a novel familial Alzheimer's disease locus on chromosome 14. Nature Genetics. 2: 330-4. PMID 1303289 DOI: 10.1038/Ng1292-330 |
0.302 |
|
| 1991 |
Farrer LA, Cupples LA, Connor L, Wolf PA, Growdon JH. Association of decreased paternal age and late-onset Alzheimer's disease. An example of genetic imprinting? Archives of Neurology. 48: 599-604. PMID 2039382 DOI: 10.1001/archneur.1991.00530180051017 |
0.353 |
|
| 1990 |
St George-Hyslop PH, Haines JL, Farrer LA, Polinsky R, Van Broeckhoven C, Goate A, McLachlan DR, Orr H, Bruni AC, Sorbi S, Rainero I, Foncin JF, Pollen D, Cantu JM, Tupler R, et al. Genetic linkage studies suggest that Alzheimer's disease is not a single homogeneous disorder. Nature. 347: 194-7. PMID 2395471 DOI: 10.1038/347194A0 |
0.365 |
|
| 1989 |
Farrer LA, O'Sullivan DM, Cupples LA, Growdon JH, Myers RH. Assessment of genetic risk for Alzheimer's disease among first-degree relatives. Annals of Neurology. 25: 485-93. PMID 2774490 DOI: 10.1002/Ana.410250511 |
0.345 |
|
| 1989 |
St George-Hyslop PH, Tanzi RE, Haines JL, Polinsky RJ, Farrer L, Myers RH, Gusella JF. Molecular genetics of familial Alzheimer's disease. European Neurology. 29: 25-7. PMID 2693103 DOI: 10.1159/000116477 |
0.349 |
|
| 1989 |
St George-Hyslop PH, Myers RH, Haines JL, Farrer LA, Tanzi RE, Abe K, James MF, Conneally PM, Polinsky RJ, Gusella JF. Familial Alzheimer's disease: progress and problems. Neurobiology of Aging. 10: 417-25. PMID 2682321 DOI: 10.1016/0197-4580(89)90082-1 |
0.411 |
|
| 1989 |
St George-Hyslop PH, Haines JL, Polinsky RJ, Tanzi RE, Farrer L, Myers RH, Gusella JF. Molecular genetics of familial Alzheimer's disease. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 16: 465-7. PMID 2680005 DOI: 10.1017/S0317167100029772 |
0.313 |
|
| 1984 |
Farrer LA, Conneally PM, Yu PI. The natural history of Huntington disease: Possible role of 'aging genes' American Journal of Medical Genetics. 18: 115-123. PMID 6234800 |
0.302 |
|
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