☰

Robert Freedman - Publications

Affiliations: 
University of Colorado Anschutz Medical Campus, Denver, Aurora, CO 
Area:
Mental Health, Pharmacology, Neuroscience Biology
Tree Info Grants Similar researchers Related pubs Distance to... Nearest Nobel PubMed Report error

237/500 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Greenwood TA, Swerdlow NR, Sprock J, Calkins ME, Freedman R, Green MF, Gur RE, Gur RC, Lazzeroni LC, Light GA, Nuechterlein KH, Radant AD, Silverman JM, Stone WS, Sugar CA, et al. Heritability of acoustic startle magnitude and latency from the consortium on the genetics of schizophrenia. Schizophrenia Research. PMID 33189519 DOI: 10.1016/j.schres.2020.11.003  0.309
2020 Freedman R, Olsen-Dufour AM, Olincy A. P50 inhibitory sensory gating in schizophrenia: analysis of recent studies. Schizophrenia Research. PMID 32061454 DOI: 10.1016/J.Schres.2020.02.003  0.431
2020 Kantrowitz JT, Javitt DC, Freedman R, Sehatpour P, Kegeles LS, Carlson M, Sobeih T, Wall MM, Choo TH, Vail B, Grinband J, Lieberman JA. Double blind, two dose, randomized, placebo-controlled, cross-over clinical trial of the positive allosteric modulator at the alpha7 nicotinic cholinergic receptor AVL-3288 in schizophrenia patients. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 32015461 DOI: 10.1038/S41386-020-0628-9  0.425
2019 Greenwood TA, Lazzeroni LC, Maihofer AX, Swerdlow NR, Calkins ME, Freedman R, Green MF, Light GA, Nievergelt CM, Nuechterlein KH, Radant AD, Siever LJ, Silverman JM, Stone WS, Sugar CA, et al. Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study. Jama Psychiatry. PMID 31596458 DOI: 10.1001/Jamapsychiatry.2019.2850  0.427
2019 Leonard S, Mexal S, Freedman R. Smoking, Genetics and Schizophrenia: Evidence for Self Medication. Journal of Dual Diagnosis. 3: 43-59. PMID 19122786 DOI: 10.1300/J374V03N03_05  0.442
2019 Freedman R. 33.4 ETHICAL CONSIDERATIONS IN PRENATAL NUTRITIONAL INTERVENTIONS FOR SCHIZOPHRENIA Schizophrenia Bulletin. 45: S144-S144. DOI: 10.1093/Schbul/Sbz022.140  0.366
2019 Tregellas J, Harris J, Freedman R. 235. Hippocampal Hyperactivity in Schizophrenia, Relationship to Cognitive Deficits, and Potential as a Target for Therapeutic Development Biological Psychiatry. 85: S97-S98. DOI: 10.1016/J.Biopsych.2019.03.249  0.637
2018 Freedman R, Hunter SK, Hoffman MC. Prenatal Primary Prevention of Mental Illness by Micronutrient Supplements in Pregnancy. The American Journal of Psychiatry. appiajp201817070836. PMID 29558816 DOI: 10.1176/Appi.Ajp.2018.17070836  0.335
2018 Wong DF, Kuwabara H, Horti AG, Roberts JM, Nandi A, Casella N, Brasic J, Weerts EM, Kitzmiller K, Phan JA, Gapasin L, Sawa A, Valentine H, Wand G, George N, ... ... Freedman R, et al. PET Brain imaging of α7-nAChR with [18F]ASEM: Reproducibility, occupancy, receptor density, and changes in schizophrenia. The International Journal of Neuropsychopharmacology. PMID 29522184 DOI: 10.1093/Ijnp/Pyy021  0.35
2018 Rahman A, Freedman R, Hollander E. S59. Alpha-7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator Galantamine in Autism Spectrum Disorder Biological Psychiatry. 83: S369-S370. DOI: 10.1016/J.Biopsych.2018.02.950  0.308
2018 Greenwood T, Lazzeroni L, Calkins ME, Freedman R, Green MF, Gur RE, Gur RC, Light G, Nuechterlein K, Olincy A, Radant A, Seidman L, Siever L, Silverman J, Stone W, et al. S209. Genome-Wide Association of Endophenotypes for Schizophrenia From the Consortium On the Genetics of Schizophrenia (COGS) Study Biological Psychiatry. 83. DOI: 10.1016/J.Biopsych.2018.02.1101  0.407
2017 Lewis AS, Olincy A, Buchanan RW, Kem WR, Picciotto MR, Freedman R. Effects of a nicotinic agonist on the Brief Psychiatric Rating Scale five-factor subscale model in schizophrenia. Schizophrenia Research. PMID 29050790 DOI: 10.1016/J.Schres.2017.10.016  0.409
2017 Kem WR, Olincy A, Johnson L, Harris J, Wagner BD, Buchanan RW, Christians U, Freedman R. Pharmacokinetic Limitations on Effects of an Alpha7 Nicotinic Receptor Agonist in Schizophrenia: Randomized Trial with an Extended Release Formulation. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. PMID 28825423 DOI: 10.1038/Npp.2017.182  0.383
2017 Gee KW, Olincy A, Kanner R, Johnson L, Hogenkamp D, Harris J, Tran M, Edmonds SA, Sauer W, Yoshimura R, Johnstone T, Freedman R. First in human trial of a type I positive allosteric modulator of alpha7-nicotinic acetylcholine receptors: Pharmacokinetics, safety, and evidence for neurocognitive effect of AVL-3288. Journal of Psychopharmacology (Oxford, England). 269881117691590. PMID 28196430 DOI: 10.1177/0269881117691590  0.361
2017 Freedman R. Endophenotypes in schizophrenia European Neuropsychopharmacology. 27. DOI: 10.1016/S0924-977X(17)30986-0  0.422
2016 Olincy A, Blakeley-Smith A, Johnson L, Kem WR, Freedman R. Brief Report: Initial Trial of Alpha7-Nicotinic Receptor Stimulation in Two Adult Patients with Autism Spectrum Disorder. Journal of Autism and Developmental Disorders. PMID 27565651 DOI: 10.1007/S10803-016-2890-6  0.388
2016 Millard SP, Shofer J, Braff D, Calkins M, Cadenhead K, Freedman R, Green MF, Greenwood TA, Gur R, Gur R, Lazzeroni LC, Light GA, Olincy A, Nuechterlein K, Seidman L, et al. Prioritizing schizophrenia endophenotypes for future genetic studies: An example using data from the COGS-1 family study. Schizophrenia Research. PMID 27132484 DOI: 10.1016/J.Schres.2016.04.011  0.393
2015 Greenwood TA, Lazzeroni LC, Calkins ME, Freedman R, Green MF, Gur RE, Gur RC, Light GA, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Stone WS, et al. Genetic assessment of additional endophenotypes from the Consortium on the Genetics of Schizophrenia Family Study. Schizophrenia Research. PMID 26597662 DOI: 10.1016/J.Schres.2015.11.008  0.393
2015 Freedman R. Molecules and psychiatry. The American Journal of Psychiatry. 172: 1051. PMID 26575442 DOI: 10.1176/Appi.Ajp.2015.15091219  0.307
2015 Greenwood TA, Light GA, Swerdlow NR, Calkins ME, Green MF, Gur RE, Gur RC, Lazzeroni LC, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Stone WS, ... ... Freedman R, et al. Gating Deficit Heritability and Correlation With Increased Clinical Severity in Schizophrenia Patients With Positive Family History. The American Journal of Psychiatry. appiajp201515050605. PMID 26441157 DOI: 10.1176/Appi.Ajp.2015.15050605  0.36
2015 Lee SH, Byrne EM, Hultman CM, Kähler A, Vinkhuyzen AA, Ripke S, Andreassen OA, Frisell T, Gusev A, Hu X, Karlsson R, Mantzioris VX, McGrath JJ, Mehta D, Stahl EA, ... ... Freedman R, et al. New data and an old puzzle: the negative association between schizophrenia and rheumatoid arthritis. International Journal of Epidemiology. PMID 26286434 DOI: 10.1093/Ije/Dyv136  0.355
2015 Freedman R, Ross RG. Prenatal choline and the development of schizophrenia. Shanghai Archives of Psychiatry. 27: 90-102. PMID 26120259 DOI: 10.11919/J.Issn.1002-0829.215006  0.432
2015 Ross RG, Freedman R. Endophenotypes in Schizophrenia for the Perinatal Period: Criteria for Validation. Schizophrenia Bulletin. 41: 824-34. PMID 25943124 DOI: 10.1093/Schbul/Sbv054  0.41
2015 Sinkus ML, Graw S, Freedman R, Ross RG, Lester HA, Leonard S. The human CHRNA7 and CHRFAM7A genes: A review of the genetics, regulation, and function. Neuropharmacology. 96: 274-88. PMID 25701707 DOI: 10.1016/J.Neuropharm.2015.02.006  0.335
2015 Wu WL, Adams CE, Stevens KE, Chow KH, Freedman R, Patterson PH. The interaction between maternal immune activation and alpha 7 nicotinic acetylcholine receptor in regulating behaviors in the offspring. Brain, Behavior, and Immunity. 46: 192-202. PMID 25683697 DOI: 10.1016/J.Bbi.2015.02.005  0.359
2015 Seidman LJ, Hellemann G, Nuechterlein KH, Greenwood TA, Braff DL, Cadenhead KS, Calkins ME, Freedman R, Gur RE, Gur RC, Lazzeroni LC, Light GA, Olincy A, Radant AD, Siever LJ, et al. Factor structure and heritability of endophenotypes in schizophrenia: findings from the Consortium on the Genetics of Schizophrenia (COGS-1). Schizophrenia Research. 163: 73-9. PMID 25682549 DOI: 10.1016/J.Schres.2015.01.027  0.408
2015 Radant AD, Millard SP, Braff DL, Calkins ME, Dobie DJ, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Lazzeroni LC, Light GA, Meichle SP, Nuechterlein KH, Olincy A, et al. Robust differences in antisaccade performance exist between COGS schizophrenia cases and controls regardless of recruitment strategies. Schizophrenia Research. 163: 47-52. PMID 25553977 DOI: 10.1016/J.Schres.2014.12.016  0.432
2015 Javitt DC, Freedman R. Sensory processing dysfunction in the personal experience and neuronal machinery of schizophrenia. The American Journal of Psychiatry. 172: 17-31. PMID 25553496 DOI: 10.1176/Appi.Ajp.2014.13121691  0.439
2015 Stone WS, Mesholam-Gately RI, Braff DL, Calkins ME, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Lazzeroni LC, Light GA, Nuechterlein KH, Olincy A, Radant AD, Siever LJ, et al. California Verbal Learning Test-II performance in schizophrenia as a function of ascertainment strategy: comparing the first and second phases of the Consortium on the Genetics of Schizophrenia (COGS). Schizophrenia Research. 163: 32-7. PMID 25497440 DOI: 10.1016/J.Schres.2014.10.029  0.342
2015 Gur RC, Braff DL, Calkins ME, Dobie DJ, Freedman R, Green MF, Greenwood TA, Lazzeroni LC, Light GA, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, et al. Neurocognitive performance in family-based and case-control studies of schizophrenia. Schizophrenia Research. 163: 17-23. PMID 25432636 DOI: 10.1016/J.Schres.2014.10.049  0.377
2014 Wang Y, Xiao C, Indersmitten T, Freedman R, Leonard S, Lester HA. The duplicated α7 subunits assemble and form functional nicotinic receptors with the full-length α7. The Journal of Biological Chemistry. 289: 26451-63. PMID 25056953 DOI: 10.1074/Jbc.M114.582858  0.333
2014 Marder SR, Freedman R. Learning from people with schizophrenia Schizophrenia Bulletin. 40: 1185-1186. PMID 24973131 DOI: 10.1093/Schbul/Sbu096  0.385
2014 Schmeidler J, Lazzeroni LC, Swerdlow NR, Ferreira RP, Braff DL, Calkins ME, Cadenhead KS, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Olincy A, Nuechterlein KH, et al. Paternal age of schizophrenia probands and endophenotypic differences from unaffected siblings. Psychiatry Research. 219: 67-71. PMID 24913833 DOI: 10.1016/J.Psychres.2014.05.035  0.38
2014 Light G, Greenwood TA, Swerdlow NR, Calkins ME, Freedman R, Green MF, Gur RE, Gur RC, Lazzeroni LC, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, et al. Comparison of the heritability of schizophrenia and endophenotypes in the COGS-1 family study. Schizophrenia Bulletin. 40: 1404-11. PMID 24903414 DOI: 10.1093/Schbul/Sbu064  0.383
2014 Tsuang D, Esterberg M, Braff D, Calkins M, Cadenhead K, Dobie D, Freedman R, Green MF, Greenwood T, Gur R, Gur R, Horan W, Lazzeroni LC, Light GA, Millard SP, et al. Is there an association between advanced paternal age and endophenotype deficit levels in schizophrenia? Plos One. 9: e88379. PMID 24523888 DOI: 10.1371/Journal.Pone.0088379  0.407
2014 Tregellas JR, Smucny J, Harris JG, Olincy A, Maharajh K, Kronberg E, Eichman LC, Lyons E, Freedman R. Intrinsic hippocampal activity as a biomarker for cognition and symptoms in schizophrenia. The American Journal of Psychiatry. 171: 549-56. PMID 24435071 DOI: 10.1176/Appi.Ajp.2013.13070981  0.649
2014 Freedman R. α7-nicotinic acetylcholine receptor agonists for cognitive enhancement in schizophrenia. Annual Review of Medicine. 65: 245-61. PMID 24111888 DOI: 10.1146/Annurev-Med-092112-142937  0.44
2013 Sinkus ML, Adams CE, Logel J, Freedman R, Leonard S. Expression of immune genes on chromosome 6p21.3-22.1 in schizophrenia. Brain, Behavior, and Immunity. 32: 51-62. PMID 23395714 DOI: 10.1016/J.Bbi.2013.01.087  0.409
2013 Calkins ME, Ray A, Gur RC, Freedman R, Green MF, Greenwood TA, Light GA, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, Siever LJ, Silverman JM, Stone WS, Sugar C, et al. Sex differences in familiality effects on neurocognitive performance in schizophrenia. Biological Psychiatry. 73: 976-84. PMID 23395246 DOI: 10.1016/J.Biopsych.2012.12.021  0.389
2013 Ross RG, Hunter SK, McCarthy L, Beuler J, Hutchison AK, Wagner BD, Leonard S, Stevens KE, Freedman R. Perinatal choline effects on neonatal pathophysiology related to later schizophrenia risk. The American Journal of Psychiatry. 170: 290-8. PMID 23318559 DOI: 10.1176/Appi.Ajp.2012.12070940  0.39
2012 Fanous AH, Zhou B, Aggen SH, Bergen SE, Amdur RL, Duan J, Sanders AR, Shi J, Mowry BJ, Olincy A, Amin F, Cloninger CR, Silverman JM, Buccola NG, Byerley WF, ... ... Freedman R, et al. Genome-wide association study of clinical dimensions of schizophrenia: polygenic effect on disorganized symptoms. The American Journal of Psychiatry. 169: 1309-17. PMID 23212062 DOI: 10.1176/Appi.Ajp.2012.12020218  0.38
2012 Freedman R. Brain development and schizophrenia. The American Journal of Psychiatry. 169: 1019-21. PMID 23032379 DOI: 10.1176/Appi.Ajp.2012.12081017  0.397
2012 Olincy A, Freedman R. Nicotinic mechanisms in the treatment of psychotic disorders: a focus on the α7 nicotinic receptor. Handbook of Experimental Pharmacology. 211-32. PMID 23027417 DOI: 10.1007/978-3-642-25758-2_8  0.446
2012 Stephens SH, Franks A, Berger R, Palionyte M, Fingerlin TE, Wagner B, Logel J, Olincy A, Ross RG, Freedman R, Leonard S. Multiple genes in the 15q13-q14 chromosomal region are associated with schizophrenia. Psychiatric Genetics. 22: 1-14. PMID 21970977 DOI: 10.1097/Ypg.0B013E32834C0C33  0.319
2011 Ripke S, Sanders AR, Kendler KS, Levinson DF, Sklar P, Holmans PA, Lin DY, Duan J, Ophoff RA, Andreassen OA, Scolnick E, Cichon S, St. Clair D, Corvin A, Gurling H, ... ... Freedman R, et al. Genome-wide association study identifies five new schizophrenia loci Nature Genetics. 43: 969-978. PMID 21926974 DOI: 10.1038/Ng.940  0.349
2011 Greenwood TA, Lazzeroni LC, Murray SS, Cadenhead KS, Calkins ME, Dobie DJ, Green MF, Gur RE, Gur RC, Hardiman G, Kelsoe JR, Leonard S, Light GA, Nuechterlein KH, Olincy A, ... ... Freedman R, et al. Analysis of 94 candidate genes and 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. The American Journal of Psychiatry. 168: 930-46. PMID 21498463 DOI: 10.1176/Appi.Ajp.2011.10050723  0.398
2011 Miwa JM, Freedman R, Lester HA. Neural systems governed by nicotinic acetylcholine receptors: emerging hypotheses. Neuron. 70: 20-33. PMID 21482353 DOI: 10.1016/J.Neuron.2011.03.014  0.362
2011 Stone WS, Giuliano AJ, Tsuang MT, Braff DL, Cadenhead KS, Calkins ME, Dobie DJ, Faraone SV, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, et al. Group and site differences on the California Verbal Learning Test in persons with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia (COGS). Schizophrenia Research. 128: 102-10. PMID 21288694 DOI: 10.1016/J.Schres.2011.01.005  0.415
2011 Levinson DF, Duan J, Oh S, Wang K, Sanders AR, Shi J, Zhang N, Mowry BJ, Olincy A, Amin F, Cloninger CR, Silverman JM, Buccola NG, Byerley WF, Black DW, ... ... Freedman R, et al. Copy number variants in schizophrenia: confirmation of five previous findings and new evidence for 3q29 microdeletions and VIPR2 duplications. The American Journal of Psychiatry. 168: 302-16. PMID 21285140 DOI: 10.1176/Appi.Ajp.2010.10060876  0.405
2011 Tregellas JR, Tanabe J, Rojas DC, Shatti S, Olincy A, Johnson L, Martin LF, Soti F, Kem WR, Leonard S, Freedman R. Effects of an alpha 7-nicotinic agonist on default network activity in schizophrenia. Biological Psychiatry. 69: 7-11. PMID 20728875 DOI: 10.1016/J.Biopsych.2010.07.004  0.668
2011 Hunter SK, Kisley MA, McCarthy L, Freedman R, Ross RG. Diminished cerebral inhibition in neonates associated with risk factors for schizophrenia: parental psychosis, maternal depression, and nicotine use. Schizophrenia Bulletin. 37: 1200-8. PMID 20403924 DOI: 10.1093/Schbul/Sbq036  0.32
2010 Olincy A, Braff DL, Adler LE, Cadenhead KS, Calkins ME, Dobie DJ, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Radant AD, Schork NJ, ... ... Freedman R, et al. Inhibition of the P50 cerebral evoked response to repeated auditory stimuli: results from the Consortium on Genetics of Schizophrenia. Schizophrenia Research. 119: 175-82. PMID 20382002 DOI: 10.1016/J.Schres.2010.03.004  0.45
2010 Radant AD, Dobie DJ, Calkins ME, Olincy A, Braff DL, Cadenhead KS, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Meichle SP, Millard SP, Mintz J, et al. Antisaccade performance in schizophrenia patients, their first-degree biological relatives, and community comparison subjects: data from the COGS study. Psychophysiology. 47: 846-56. PMID 20374545 DOI: 10.1111/J.1469-8986.2010.01004.X  0.421
2010 Freedman R. Psychiatrists' role in the health of the pregnant mother and the risk for schizophrenia in her offspring. The American Journal of Psychiatry. 167: 239-40. PMID 20194483 DOI: 10.1176/Appi.Ajp.2009.09121755  0.359
2010 Tregellas JR, Olincy A, Johnson L, Tanabe J, Shatti S, Martin LF, Singel D, Du YP, Soti F, Kem WR, Freedman R. Functional magnetic resonance imaging of effects of a nicotinic agonist in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 35: 938-42. PMID 19956085 DOI: 10.1038/Npp.2009.196  0.673
2010 Ross RG, Stevens KE, Proctor WR, Leonard S, Kisley MA, Hunter SK, Freedman R, Adams CE. Research review: Cholinergic mechanisms, early brain development, and risk for schizophrenia. Journal of Child Psychology and Psychiatry, and Allied Disciplines. 51: 535-49. PMID 19925602 DOI: 10.1111/J.1469-7610.2009.02187.X  0.43
2010 Freedman R, Goldowitz D. Studies on the hippocampal formation: From basic development to clinical applications: Studies on schizophrenia. Progress in Neurobiology. 90: 263-75. PMID 19853005 DOI: 10.1016/J.Pneurobio.2009.10.008  0.444
2010 Mexal S, Berger R, Logel J, Ross RG, Freedman R, Leonard S. Differential regulation of alpha7 nicotinic receptor gene (CHRNA7) expression in schizophrenic smokers. Journal of Molecular Neuroscience : Mn. 40: 185-95. PMID 19680823 DOI: 10.1007/S12031-009-9233-4  0.344
2009 Sinkus ML, Lee MJ, Gault J, Logel J, Short M, Freedman R, Christian SL, Lyon J, Leonard S. A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia. Brain Research. 1291: 1-11. PMID 19631623 DOI: 10.1016/J.Brainres.2009.07.041  0.383
2009 Shi J, Levinson DF, Duan J, Sanders AR, Zheng Y, Pe'er I, Dudbridge F, Holmans PA, Whittemore AS, Mowry BJ, Olincy A, Amin F, Cloninger CR, Silverman JM, Buccola NG, ... ... Freedman R, et al. Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature. 460: 753-7. PMID 19571809 DOI: 10.1038/Nature08192  0.401
2009 Hodge SE, Freedman R. Zeroing in on a schizophrenia gene: a new tool to assess the probability. The American Journal of Psychiatry. 166: 392-4. PMID 19339362 DOI: 10.1176/Appi.Ajp.2009.09010006  0.373
2009 Stephens SH, Logel J, Barton A, Franks A, Schultz J, Short M, Dickenson J, James B, Fingerlin TE, Wagner B, Hodgkinson C, Graw S, Ross RG, Freedman R, Leonard S. Association of the 5'-upstream regulatory region of the alpha7 nicotinic acetylcholine receptor subunit gene (CHRNA7) with schizophrenia. Schizophrenia Research. 109: 102-12. PMID 19181484 DOI: 10.1016/J.Schres.2008.12.017  0.45
2008 Turetsky BI, Greenwood TA, Olincy A, Radant AD, Braff DL, Cadenhead KS, Dobie DJ, Freedman R, Green MF, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Schork NJ, et al. Abnormal auditory N100 amplitude: a heritable endophenotype in first-degree relatives of schizophrenia probands. Biological Psychiatry. 64: 1051-9. PMID 18701089 DOI: 10.1016/J.Biopsych.2008.06.018  0.437
2008 Simosky JK, Freedman R, Stevens KE. Olanzapine improves deficient sensory inhibition in DBA/2 mice. Brain Research. 1233: 129-36. PMID 18687314 DOI: 10.1016/J.Brainres.2008.07.057  0.798
2008 O'Donovan MC, Craddock N, Norton N, Williams H, Peirce T, Moskvina V, Nikolov I, Hamshere M, Carroll L, Georgieva L, Dwyer S, Holmans P, Marchini JL, Spencer CC, Howie B, ... ... Freedman R, et al. Identification of loci associated with schizophrenia by genome-wide association and follow-up. Nature Genetics. 40: 1053-5. PMID 18677311 DOI: 10.1038/Ng.201  0.332
2008 Horan WP, Braff DL, Nuechterlein KH, Sugar CA, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Olincy A, Radant AD, et al. Verbal working memory impairments in individuals with schizophrenia and their first-degree relatives: findings from the Consortium on the Genetics of Schizophrenia. Schizophrenia Research. 103: 218-28. PMID 18406578 DOI: 10.1016/J.Schres.2008.02.014  0.415
2008 Freedman R. Cannabis, inhibitory neurons, and the progressive course of schizophrenia. The American Journal of Psychiatry. 165: 416-9. PMID 18381910 DOI: 10.1176/Appi.Ajp.2008.08010147  0.409
2008 Freedman R, Olincy A, Buchanan RW, Harris JG, Gold JM, Johnson L, Allensworth D, Guzman-Bonilla A, Clement B, Ball MP, Kutnick J, Pender V, Martin LF, Stevens KE, Wagner BD, et al. Initial phase 2 trial of a nicotinic agonist in schizophrenia. The American Journal of Psychiatry. 165: 1040-7. PMID 18381905 DOI: 10.1176/Appi.Ajp.2008.07071135  0.425
2008 Sanders AR, Duan J, Levinson DF, Shi J, He D, Hou C, Burrell GJ, Rice JP, Nertney DA, Olincy A, Rozic P, Vinogradov S, Buccola NG, Mowry BJ, Freedman R, et al. No significant association of 14 candidate genes with schizophrenia in a large European ancestry sample: implications for psychiatric genetics. The American Journal of Psychiatry. 165: 497-506. PMID 18198266 DOI: 10.1176/Appi.Ajp.2007.07101573  0.324
2008 Mexal S, Berger R, Pearce L, Barton A, Logel J, Adams CE, Ross RG, Freedman R, Leonard S. Regulation of a novel alphaN-catenin splice variant in schizophrenic smokers. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 759-68. PMID 18163523 DOI: 10.1002/Ajmg.B.30679  0.311
2008 Tanabe J, Crowley T, Hutchison K, Miller D, Johnson G, Du YP, Zerbe G, Freedman R. Ventral striatal blood flow is altered by acute nicotine but not withdrawal from nicotine Neuropsychopharmacology. 33: 627-633. PMID 17460613 DOI: 10.1038/Sj.Npp.1301428  0.318
2008 Tregellas JR, Freedman R. Nicotinic cholinergic cortical dysfunction in schizophrenia Cortical Deficits in Schizophrenia: From Genes to Function. 97-111. DOI: 10.1007/978-0-387-74351-6_5  0.636
2007 Martin LF, Hall MH, Ross RG, Zerbe G, Freedman R, Olincy A. Physiology of schizophrenia, bipolar disorder, and schizoaffective disorder American Journal of Psychiatry. 164: 1900-1906. PMID 18056246 DOI: 10.1176/Appi.Ajp.2007.06010017  0.398
2007 Greenwood TA, Braff DL, Light GA, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Green MF, Gur RE, Gur RC, Mintz J, Nuechterlein KH, Olincy A, Radant AD, Seidman LJ, et al. Initial heritability analyses of endophenotypic measures for schizophrenia: the consortium on the genetics of schizophrenia. Archives of General Psychiatry. 64: 1242-50. PMID 17984393 DOI: 10.1001/Archpsyc.64.11.1242  0.414
2007 Freedman R. Exacerbation of schizophrenia by varenicline. The American Journal of Psychiatry. 164: 1269. PMID 17671295 DOI: 10.1176/Appi.Ajp.2007.07020326  0.325
2007 Buchanan RW, Freedman R, Javitt DC, Abi-Dargham A, Lieberman JA. Recent advances in the development of novel pharmacological agents for the treatment of cognitive impairments in schizophrenia. Schizophrenia Bulletin. 33: 1120-30. PMID 17641146 DOI: 10.1093/Schbul/Sbm083  0.365
2007 Martin LF, Freedman R. Schizophrenia and the α7 Nicotinic Acetylcholine Receptor International Review of Neurobiology. 78: 225-246. PMID 17349863 DOI: 10.1016/S0074-7742(06)78008-4  0.456
2007 Swerdlow NR, Sprock J, Light GA, Cadenhead K, Calkins ME, Dobie DJ, Freedman R, Green MF, Greenwood TA, Gur RE, Mintz J, Olincy A, Nuechterlein KH, Radant AD, Schork NJ, et al. Multi-site studies of acoustic startle and prepulse inhibition in humans: initial experience and methodological considerations based on studies by the Consortium on the Genetics of Schizophrenia. Schizophrenia Research. 92: 237-51. PMID 17346930 DOI: 10.1016/J.Schres.2007.01.012  0.339
2007 Tregellas JR, Davalos DB, Rojas DC, Waldo MC, Gibson L, Wylie K, Du YP, Freedman R. Increased hemodynamic response in the hippocampus, thalamus and prefrontal cortex during abnormal sensory gating in schizophrenia. Schizophrenia Research. 92: 262-72. PMID 17336502 DOI: 10.1016/J.Schres.2006.12.033  0.678
2007 Freedman R. Neuronal dysfunction and schizophrenia symptoms. The American Journal of Psychiatry. 164: 385-90. PMID 17329460 DOI: 10.1176/Ajp.2007.164.3.385  0.392
2007 Martin LF, Leonard S, Hall MH, Tregellas JR, Freedman R, Olincy A. Sensory gating and alpha-7 nicotinic receptor gene allelic variants in schizoaffective disorder, bipolar type. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 144: 611-4. PMID 17192894 DOI: 10.1002/Ajmg.B.30470  0.645
2007 Freedman R, Carpenter WT, Davis JM, Goldman HH, Tamminga CA, Thomas M. The costs of drugs for schizophrenia. The American Journal of Psychiatry. 163: 2029-31. PMID 17151146 DOI: 10.1176/ajp.2006.163.12.2029  0.365
2007 Braff DL, Freedman R, Schork NJ, Gottesman II. Deconstructing schizophrenia: an overview of the use of endophenotypes in order to understand a complex disorder. Schizophrenia Bulletin. 33: 21-32. PMID 17088422 DOI: 10.1093/Schbul/Sbl049  0.427
2007 Calkins ME, Dobie DJ, Cadenhead KS, Olincy A, Freedman R, Green MF, Greenwood TA, Gur RE, Gur RC, Light GA, Mintz J, Nuechterlein KH, Radant AD, Schork NJ, Seidman LJ, et al. The Consortium on the Genetics of Endophenotypes in Schizophrenia: model recruitment, assessment, and endophenotyping methods for a multisite collaboration. Schizophrenia Bulletin. 33: 33-48. PMID 17035358 DOI: 10.1093/Schbul/Sbl044  0.376
2007 Radant AD, Dobie DJ, Calkins ME, Olincy A, Braff DL, Cadenhead KS, Freedman R, Green MF, Greenwood TA, Gur RE, Light GA, Meichle SP, Mintz J, Nuechterlein KH, Schork NJ, et al. Successful multi-site measurement of antisaccade performance deficits in schizophrenia. Schizophrenia Research. 89: 320-9. PMID 17023145 DOI: 10.1016/J.Schres.2006.08.010  0.408
2006 Mexal S, Berger R, Adams CE, Ross RG, Freedman R, Leonard S. Brain pH has a significant impact on human postmortem hippocampal gene expression profiles Brain Research. 1106: 1-11. PMID 16843448 DOI: 10.1016/J.Brainres.2006.05.043  0.323
2006 Leonard S, Freedman R. Genetics of chromosome 15q13-q14 in schizophrenia. Biological Psychiatry. 60: 115-22. PMID 16843094 DOI: 10.1016/J.Biopsych.2006.03.054  0.392
2006 Olincy A, Harris JG, Johnson LL, Pender V, Kongs S, Allensworth D, Ellis J, Zerbe GO, Leonard S, Stevens KE, Stevens JO, Martin L, Adler LE, Soti F, Kem WR, ... Freedman R, et al. Proof-of-concept trial of an alpha7 nicotinic agonist in schizophrenia. Archives of General Psychiatry. 63: 630-8. PMID 16754836 DOI: 10.1001/Archpsyc.63.6.630  0.463
2006 Freedman R, Leonard S, Waldo M, Gault J, Olincy A, Adler LE. Characterization of allelic variants at chromosome 15q14 in schizophrenia Genes, Brain and Behavior. 5: 14-22. PMID 16417613 DOI: 10.1111/J.1601-183X.2006.00190.X  0.376
2006 Tanabe J, Tregellas JR, Martin LF, Freedman R. Effects of nicotine on hippocampal and cingulate activity during smooth pursuit eye movement in schizophrenia. Biological Psychiatry. 59: 754-61. PMID 16259965 DOI: 10.1016/J.Biopsych.2005.09.004  0.638
2005 Davalos DB, Kisley MA, Freedman R. Behavioral and electrophysiological indices of temporal processing dysfunction in schizophrenia. The Journal of Neuropsychiatry and Clinical Neurosciences. 17: 517-25. PMID 16387992 DOI: 10.1176/Jnp.17.4.517  0.355
2005 Freedman R. The choice of antipsychotic drugs for schizophrenia. The New England Journal of Medicine. 353: 1286-8. PMID 16172204 DOI: 10.1056/Nejme058200  0.364
2005 Hashimoto K, Iyo M, Freedman R, Stevens KE. Tropisetron improves deficient inhibitory auditory processing in DBA/2 mice: role of alpha 7 nicotinic acetylcholine receptors. Psychopharmacology. 183: 13-9. PMID 16136299 DOI: 10.1007/S00213-005-0142-0  0.398
2005 Mexal S, Frank M, Berger R, Adams CE, Ross RG, Freedman R, Leonard S. Differential modulation of gene expression in the NMDA postsynaptic density of schizophrenic and control smokers. Molecular Brain Research. 139: 317-332. PMID 16122832 DOI: 10.1016/J.Molbrainres.2005.06.006  0.319
2005 Freedman R, Ross R, Leonard S, Myles-Worsley M, Adams CE, Waldo M, Tregellas J, Martin L, Olincy A, Tanabe J, Kisley MA, Hunter S, Stevens KE. Early biomarkers of psychosis. Dialogues in Clinical Neuroscience. 7: 17-29. PMID 16060593  0.629
2005 Koike K, Hashimoto K, Takai N, Shimizu E, Komatsu N, Watanabe H, Nakazato M, Okamura N, Stevens KE, Freedman R, Iyo M. Tropisetron improves deficits in auditory P50 suppression in schizophrenia. Schizophrenia Research. 76: 67-72. PMID 15927799 DOI: 10.1016/J.Schres.2004.12.016  0.471
2005 Tregellas JR, Tanabe JL, Martin LF, Freedman R. FMRI of response to nicotine during a smooth pursuit eye movement task in schizophrenia. The American Journal of Psychiatry. 162: 391-3. PMID 15677609 DOI: 10.1176/Appi.Ajp.162.2.391  0.656
2004 Adler LE, Olincy A, Cawthra EM, McRae KA, Harris JG, Nagamoto HT, Waldo MC, Hall MH, Bowles A, Woodward L, Ross RG, Freedman R. Varied effects of atypical neuroleptics on P50 auditory gating in schizophrenia patients. The American Journal of Psychiatry. 161: 1822-8. PMID 15465979 DOI: 10.1176/Ajp.161.10.1822  0.438
2004 Martin LF, Kem WR, Freedman R. Alpha-7 nicotinic receptor agonists: Potential new candidates for the treatment of schizophrenia Psychopharmacology. 174: 54-64. PMID 15205879 DOI: 10.1007/S00213-003-1750-1  0.458
2004 Harris JG, Kongs S, Allensworth D, Martin L, Tregellas J, Sullivan B, Zerbe G, Freedman R. Effects of nicotine on cognitive deficits in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 29: 1378-85. PMID 15138435 DOI: 10.1038/Sj.Npp.1300450  0.654
2004 Myles-Worsley M, Ord L, Blailes F, Ngiralmau H, Freedman R. P50 sensory gating in adolescents from a pacific island isolate with elevated risk for schizophrenia. Biological Psychiatry. 55: 663-7. PMID 15038993 DOI: 10.1016/J.Biopsych.2003.12.006  0.397
2004 Tregellas JR, Tanabe JL, Miller DE, Ross RG, Olincy A, Freedman R. Neurobiology of smooth pursuit eye movement deficits in schizophrenia: an fMRI study. The American Journal of Psychiatry. 161: 315-21. PMID 14754781 DOI: 10.1176/Appi.Ajp.161.2.315  0.645
2003 Freedman R. Schizophrenia. The New England Journal of Medicine. 349: 1738-49. PMID 14585943 DOI: 10.1056/NEJMra035458  0.308
2003 Gault J, Hopkins J, Berger R, Drebing C, Logel J, Walton C, Short M, Vianzon R, Olincy A, Ross RG, Adler LE, Freedman R, Leonard S. Comparison of polymorphisms in the alpha7 nicotinic receptor gene and its partial duplication in schizophrenic and control subjects. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics. 123: 39-49. PMID 14582144 DOI: 10.1002/Ajmg.B.20061  0.404
2003 Kisley MA, Olincy A, Robbins E, Polk SD, Adler LE, Waldo MC, Freedman R. Sensory gating impairment associated with schizophrenia persists into REM sleep. Psychophysiology. 40: 29-38. PMID 12751801 DOI: 10.1111/1469-8986.00004  0.346
2003 Kisley MA, Polk SD, Ross RG, Levisohn PM, Freedman R. Early postnatal development of sensory gating. Neuroreport. 14: 693-7. PMID 12692465 DOI: 10.1097/00001756-200304150-00007  0.342
2003 Freedman R, Olincy A, Ross RG, Waldo MC, Stevens KE, Adler LE, Leonard S. The genetics of sensory gating deficits in schizophrenia. Current Psychiatry Reports. 5: 155-61. PMID 12685995 DOI: 10.1007/S11920-003-0032-2  0.498
2003 Simosky JK, Stevens KE, Adler LE, Freedman R. Clozapine improves deficient inhibitory auditory processing in DBA/2 mice, via a nicotinic cholinergic mechanism. Psychopharmacology. 165: 386-96. PMID 12459928 DOI: 10.1007/S00213-002-1285-X  0.812
2003 Davalos D, Kisley M, Ross R, Ellis J, Freedman R. Mismatch negativity and behavioral indices of auditory temporal processing in schizophrenia Schizophrenia Research. 60: 249-250. DOI: 10.1016/S0920-9964(03)81270-7  0.394
2003 Tregellas J, Tanabe J, Miller D, Ross R, Freedman R. FMRI of smooth pursuit eye movement abnormalities in schizophrenia Schizophrenia Research. 60: 235. DOI: 10.1016/S0920-9964(03)81231-8  0.639
2002 Simosky JK, Stevens KE, Freedman R. Nicotinic agonists and psychosis. Current Drug Targets. Cns and Neurological Disorders. 1: 149-62. PMID 12769624 DOI: 10.2174/1568007024606168  0.811
2002 Leonard S, Gault J, Hopkins J, Logel J, Vianzon R, Short M, Drebing C, Berger R, Venn D, Sirota P, Zerbe G, Olincy A, Ross RG, Adler LE, Freedman R. Association of promoter variants in the alpha7 nicotinic acetylcholine receptor subunit gene with an inhibitory deficit found in schizophrenia. Archives of General Psychiatry. 59: 1085-96. PMID 12470124 DOI: 10.1001/Archpsyc.59.12.1085  0.441
2002 Ross RG, Olincy A, Mikulich SK, Radant AD, Harris JG, Waldo M, Compagnon N, Heinlein S, Leonard S, Zerbe GO, Adler L, Freedman R. Admixture analysis of smooth pursuit eye movements in probands with schizophrenia and their relatives suggests gain and leading saccades are potential endophenotypes. Psychophysiology. 39: 809-19. PMID 12462508 DOI: 10.1017/S0048577202011691  0.383
2002 Tanabe J, Tregellas J, Miller D, Ross RG, Freedman R. Brain activation during smooth-pursuit eye movements. Neuroimage. 17: 1315-24. PMID 12414271 DOI: 10.1006/Nimg.2002.1263  0.57
2002 Tregellas JR, Tanabe JL, Miller DE, Freedman R. Monitoring eye movements during fMRI tasks with echo planar images. Human Brain Mapping. 17: 237-43. PMID 12395391 DOI: 10.1002/Hbm.10070  0.556
2002 Harris JG, Young DA, Rojas DC, Cajade-Law A, Scherzinger A, Nawroz S, Adler LE, Cullum CM, Simon J, Freedman R. Increased hippocampal volume in schizophrenics' parents with ancestral history of schizophrenia. Schizophrenia Research. 55: 11-7. PMID 11955959 DOI: 10.1016/S0920-9964(01)00272-9  0.376
2002 Tanabe J, Miller D, Tregellas J, Freedman R, Meyer FG. Comparison of detrending methods for optimal fMRI preprocessing. Neuroimage. 15: 902-7. PMID 11906230 DOI: 10.1006/Nimg.2002.1053  0.541
2002 Freedman R, Adler LE, Olincy A, Waldo MC, Ross RG, Stevens KE, Leonard S. Input dysfunction, schizotypy, and genetic models of schizophrenia. Schizophrenia Research. 54: 25-32. PMID 11853975 DOI: 10.1016/S0920-9964(01)00348-6  0.45
2002 Freedman R, Leonard S. Genetic linkage to schizophrenia at chromosome 15q14. American Journal of Medical Genetics. 105: 655-7. PMID 11803510 DOI: 10.1002/Ajmg.1548  0.355
2001 Freedman R, Leonard S, Olincy A, Kaufmann CA, Malaspina D, Cloninger CR, Svrakic D, Faraone SV, Tsuang MT. Evidence for the multigenic inheritance of schizophrenia. American Journal of Medical Genetics. 105: 794-800. PMID 11803533 DOI: 10.1002/Ajmg.10100  0.405
2001 Leonard S, Adler LE, Benhammou K, Berger R, Breese CR, Drebing C, Gault J, Lee MJ, Logel J, Olincy A, Ross RG, Stevens K, Sullivan B, Vianzon R, Virnich DE, ... ... Freedman R, et al. Smoking and mental illness. Pharmacology, Biochemistry, and Behavior. 70: 561-70. PMID 11796154 DOI: 10.1016/S0091-3057(01)00677-3  0.425
2001 Adams CE, Stitzel JA, Collins AC, Freedman R. Alpha7-nicotinic receptor expression and the anatomical organization of hippocampal interneurons. Brain Research. 922: 180-90. PMID 11743948 DOI: 10.1016/S0006-8993(01)03115-8  0.304
2001 Simosky JK, Stevens KE, Kem WR, Freedman R. Intragastric DMXB-A, an alpha7 nicotinic agonist, improves deficient sensory inhibition in DBA/2 mice. Biological Psychiatry. 50: 493-500. PMID 11600102 DOI: 10.1016/S0006-3223(01)01093-9  0.794
2001 Kisley MA, Olincy A, Freedman R. The effect of state on sensory gating: comparison of waking, REM and non-REM sleep. Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology. 112: 1154-65. PMID 11516727 DOI: 10.1016/S1388-2457(01)00578-8  0.334
2001 Freedman R, Leonard S, Gault JM, Hopkins J, Cloninger CR, Kaufmann CA, Tsuang MT, Farone SV, Malaspina D, Svrakic DM, Sanders A, Gejman P. Linkage disequilibrium for schizophrenia at the chromosome 15q13-14 locus of the alpha7-nicotinic acetylcholine receptor subunit gene (CHRNA7). American Journal of Medical Genetics. 105: 20-2. PMID 11424985 DOI: 10.1002/1096-8628(20010108)105:1<20::Aid-Ajmg1047>3.0.Co;2-C  0.43
2001 Adler LE, Olincy A, Cawthra E, Hoffer M, Nagamoto HT, Amass L, Freedman R. Reversal of diminished inhibitory sensory gating in cocaine addicts by a nicotinic cholinergic mechanism. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 24: 671-9. PMID 11331147 DOI: 10.1016/S0893-133X(00)00242-6  0.334
2001 Freedman R, Adams CE, Leonard S. The alpha7-nicotinic acetylcholine receptor and the pathology of hippocampal interneurons in schizophrenia. Journal of Chemical Neuroanatomy. 20: 299-306. PMID 11207427 DOI: 10.1016/S0891-0618(00)00109-5  0.423
2001 Tregellas JR, Tanabe JL, Miller D, Freedman R. Activation and habituation during smooth pursuit eye movements as revealed by fMRI Neuroimage. 13: 1271. DOI: 10.1016/S1053-8119(01)92585-6  0.553
2000 Buervenich S, Carmine A, Arvidsson M, Xiang F, Zhang Z, Sydow O, Jönsson EG, Sedvall GC, Leonard S, Ross RG, Freedman R, Chowdari KV, Nimgaonkar VL, Perlmann T, Anvret M, et al. NURR1 mutations in cases of schizophrenia and manic-depressive disorder. American Journal of Medical Genetics. 96: 808-13. PMID 11121187 DOI: 10.1002/1096-8628(20001204)96:6<808::Aid-Ajmg23>3.0.Co;2-E  0.323
2000 Adams CE, Stevens KE, Kem WR, Freedman R. Inhibition of nitric oxide synthase prevents alpha 7 nicotinic receptor-mediated restoration of inhibitory auditory gating in rat hippocampus. Brain Research. 877: 235-44. PMID 10986337 DOI: 10.1016/S0006-8993(00)02677-9  0.327
2000 Olincy A, Ross RG, Harris JG, Young DA, McAndrews MA, Cawthra E, McRae KA, Sullivan B, Adler LE, Freedman R. The P50 auditory event-evoked potential in adult attention-deficit disorder: comparison with schizophrenia. Biological Psychiatry. 47: 969-77. PMID 10838065 DOI: 10.1016/S0006-3223(00)00239-0  0.39
2000 Freedman R, Adams CE, Adler LE, Bickford PC, Gault J, Harris JG, Nagamoto HT, Olincy A, Ross RG, Stevens KE, Waldo M, Leonard S. Inhibitory neurophysiological deficit as a phenotype for genetic investigation of schizophrenia. American Journal of Medical Genetics. 97: 58-64. PMID 10813805 DOI: 10.1002/(Sici)1096-8628(200021)97:1<58::Aid-Ajmg8>3.0.Co;2-Y  0.471
2000 Leonard S, Breese C, Adams C, Benhammou K, Gault J, Stevens K, Lee M, Adler L, Olincy A, Ross R, Freedman R. Smoking and schizophrenia : abnormal nicotinic receptor expression European Journal of Pharmacology. 393: 237-242. PMID 10771019 DOI: 10.1016/S0014-2999(00)00035-2  0.429
2000 Waldo MC, Adler LE, Leonard S, Olincy A, Ross RG, Harris JG, Freedman R. Familial transmission of risk factors in the first-degree relatives of schizophrenic people. Biological Psychiatry. 47: 231-9. PMID 10682220 DOI: 10.1016/S0006-3223(99)00272-3  0.435
2000 Olincy A, Ross RG, Freedman R. 116. The effects of aging in schizophrenia on an antisaccade eye movement task Biological Psychiatry. 47. DOI: 10.1016/S0006-3223(00)00378-4  0.359
1999 Waldo MC, Freedman R. Neurobiological abnormalities in the relatives of schizophrenics Journal of Psychiatric Research. 33: 491-495. PMID 10628524 DOI: 10.1016/S0022-3956(99)00025-4  0.403
1999 Freedman R. Schizophrenia as a neuronal illness. Biological Psychiatry. 46: 587-588. PMID 10472412 DOI: 10.1016/S0006-3223(99)00154-7  0.398
1999 Ross RG, Olincy A, Harris JG, Radant A, Adler LE, Compagnon N, Freedman R. The effects of age on a smooth pursuit tracking task in adults with schizophrenia and normal subjects. Biological Psychiatry. 46: 383-91. PMID 10435204 DOI: 10.1016/S0006-3223(98)00369-2  0.334
1999 Adler LE, Freedman R, Ross RG, Olincy A, Waldo MC. Elementary phenotypes in the neurobiological and genetic study of schizophrenia Biological Psychiatry. 46: 8-18. PMID 10394470 DOI: 10.1016/S0006-3223(99)00085-2  0.464
1999 Ross RG, Olincy A, Harris JG, Radant A, Hawkins M, Adler LE, Freedman R. Evidence for bilineal inheritance of physiological indicators of risk in childhood-onset schizophrenia. American Journal of Medical Genetics. 88: 188-99. PMID 10206241 DOI: 10.1002/(Sici)1096-8628(19990416)88:2<188::Aid-Ajmg17>3.0.Co;2-E  0.412
1999 Freedman R, Adler LE, Leonard S. Alternative phenotypes for the complex genetics of schizophrenia. Biological Psychiatry. 45: 551-8. PMID 10088045 DOI: 10.1016/S0006-3223(98)00321-7  0.452
1999 Jensen J, Coon H, Hoff M, Rosenthal J, Reimherr F, Wender P, Myles-Worsley M, Freedman R, Byerley W. Search for a schizophrenia susceptibility gene on chromosome 13. Psychiatric Genetics. 8: 239-43. PMID 9861643 DOI: 10.1097/00041444-199808040-00007  0.372
1999 Leonard S, Stevens K, Bickford P, Adler L, Freedman R. Modeling sensory processing deficits of schizophrenia in laboratory animals European Neuropsychopharmacology. 9: 154. DOI: 10.1016/S0924-977X(99)80033-9  0.413
1998 Freedman R. Biological Phenotypes In The Genetics Of Schizophrenia Biological Psychiatry. 44: 939-940. PMID 9821557 DOI: 10.1016/S0006-3223(98)00271-6  0.4
1998 Ross RG, Olincy A, Harris JG, Radant A, Adler LE, Freedman R. Anticipatory saccades during smooth pursuit eye movements and familial transmission of schizophrenia. Biological Psychiatry. 44: 690-7. PMID 9798072 DOI: 10.1016/S0006-3223(98)00052-3  0.36
1998 Vallada H, Curtis D, Sham P, Kunugi H, Zhao J, Murray R, McGuffin P, Nanko S, Owen M, Gill M, Collier D, Antonarakis S, Housman D, Kazazian H, Nestadt G, ... ... Freedman R, et al. A transmission disequilibrium and linkage analysis of D22S278 marker alleles in 574 families: further support for a susceptibility locus for schizophrenia at 22q12 Schizophrenia Research. 32: 115-121. PMID 9713907 DOI: 10.1016/S0920-9964(98)00048-6  0.409
1998 Leonard S, Gault J, Moore T, Hopkins J, Robinson M, Olincy A, Adler LE, Cloninger CR, Kaufmann CA, Tsuang MT, Faraone SV, Malaspina D, Svrakic DM, Freedman R. Further investigation of a chromosome 15 locus in schizophrenia: analysis of affected sibpairs from the NIMH Genetics Initiative. American Journal of Medical Genetics. 81: 308-12. PMID 9674976 DOI: 10.1002/(Sici)1096-8628(19980710)81:4<308::Aid-Ajmg6>3.0.Co;2-P  0.426
1998 Griffith JM, O'Neill JE, Petty F, Garver D, Young D, Freedman R. Nicotinic receptor desensitization and sensory gating deficits in schizophrenia. Biological Psychiatry. 44: 98-106. PMID 9646891 DOI: 10.1016/S0006-3223(97)00362-4  0.445
1998 Adler LE, Olincy A, Waldo M, Harris JG, Griffith J, Stevens K, Flach K, Nagamoto H, Bickford P, Leonard S, Freedman R. Schizophrenia, sensory gating, and nicotinic receptors. Schizophrenia Bulletin. 24: 189-202. PMID 9613620 DOI: 10.1093/Oxfordjournals.Schbul.A033320  0.485
1998 Stevens KE, Kem WR, Mahnir VM, Freedman R. Selective alpha7-nicotinic agonists normalize inhibition of auditory response in DBA mice. Psychopharmacology. 136: 320-7. PMID 9600576 DOI: 10.1007/S002130050573  0.389
1998 Ross RG, Harris JG, Olincy A, Radant A, Adler LE, Freedman R. Familial transmission of two independent saccadic abnormalities in schizophrenia. Schizophrenia Research. 30: 59-70. PMID 9542789 DOI: 10.1016/S0920-9964(97)00133-3  0.39
1998 Olincy A, Ross RG, Young DA, Roath M, Freedman R. Improvement in smooth pursuit eye movements after cigarette smoking in schizophrenic patients. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 18: 175-85. PMID 9471115 DOI: 10.1016/S0893-133X(97)00095-X  0.308
1998 Leonard S, Breese CR, Gault J, Adler L, Olincy A, Lee M, Freedman R. Schizophrenia and nicotinic receptors: Gene expression and genetic linkage studies European Neuropsychopharmacology. 8. DOI: 10.1016/S0924-977X(98)80119-3  0.42
1998 Olincy A, Leonard S, Young DA, Sullivan B, Freedman R. 360. Elevation of bombesin by smoking is decreased in schizophrenia Biological Psychiatry. 43. DOI: 10.1016/S0006-3223(98)90808-3  0.381
1997 Olincy A, Young DA, Freedman R. Increased levels of the nicotine metabolite cotinine in schizophrenic smokers compared to other smokers. Biological Psychiatry. 42: 1-5. PMID 9193735 DOI: 10.1016/S0006-3223(96)00302-2  0.363
1997 Freedman R, Coon H, Myles-Worsley M, Orr-Urtreger A, Olincy A, Davis A, Polymeropoulos M, Holik J, Hopkins J, Hoff M, Rosenthal J, Waldo MC, Reimherr F, Wender P, Yaw J, et al. Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus. Proceedings of the National Academy of Sciences of the United States of America. 94: 587-92. PMID 9012828 DOI: 10.1073/Pnas.94.2.587  0.468
1997 Adams CE, DeMasters BK, Freedman R. Regional zinc staining in postmortem hippocampus from schizophrenic patients. Schizophrenia Research. 18: 71-7. PMID 8929763 DOI: 10.1016/0920-9964(95)00041-0  0.369
1997 Nagamoto HT, Adler LE, Huettl P, Gerhardt G, Hea R, Cawthra E, Griffith J, Freedman R. Improved P50 auditory gating in schizophrenia with clozapine Schizophrenia Research. 24: 235. DOI: 10.1016/S0920-9964(97)82678-3  0.423
1997 Adler LE, McRae KA, Cawthra E, Ascarrunz F, Gerhardt G, Huettl P, Levin D, Abrams R, Freedman R. P50 Auditory gating, FFTs, and plasma metabolites in schizophrenia Schizophrenia Research. 24: 231. DOI: 10.1016/S0920-9964(97)82664-3  0.387
1997 Stevens KE, Collins AC, Marks MJ, Stitzel JA, Freedman R. Inheritance of a schizophrenia-like deficit in auditory gating fits a one gene model in inbred mouse strains Schizophrenia Research. 24: 60. DOI: 10.1016/S0920-9964(97)82167-6  0.387
1997 Leonard S, Byerley W, Myles-Worsley M, Olincy A, Waldo M, Adler L, Coon H, Freedman R. Linkage of a chromosome 15 locus to a neurophysiological deficit in schizophrenia Schizophrenia Research. 24: 52. DOI: 10.1016/S0920-9964(97)82148-2  0.4
1996 Freedman R, Adler LE, Myles-Worsley M, Nagamoto HT, Miller C, Kisley M, McRae K, Cawthra E, Waldo M. Inhibitory gating of an evoked response to repeated auditory stimuli in schizophrenic and normal subjects. Human recordings, computer simulation, and an animal model. Archives of General Psychiatry. 53: 1114-21. PMID 8956677 DOI: 10.1001/Archpsyc.1996.01830120052009  0.356
1996 McCarley RW, Hsiao JK, Freedman R, Pfefferbaum A, Donchin E. Neuroimaging and the cognitive neuroscience of schizophrenia. Schizophrenia Bulletin. 22: 703-25. PMID 8938923 DOI: 10.1093/Schbul/22.4.703  0.412
1996 Yaw J, Myles-Worsley M, Hoff M, Holik J, Freedman R, Byerley W, Coon H. Anticipation in multiplex schizophrenia pedigrees. Psychiatric Genetics. 6: 7-11. PMID 8925257 DOI: 10.1097/00041444-199621000-00002  0.401
1996 Leonard S, Adams C, Breese CR, Adler LE, Bickford P, Byerley W, Coon H, Griffith JM, Miller C, Myles-Worsley M, Nagamoto HT, Rollins Y, Stevens KE, Waldo M, Freedman R. Nicotinic receptor function in schizophrenia. Schizophrenia Bulletin. 22: 431-45. PMID 8873294 DOI: 10.1093/Schbul/22.3.431  0.481
1996 Stevens KE, Freedman R, Collins AC, Hall M, Leonard S, Marks MJ, Rose GM. Genetic correlation of inhibitory gating of hippocampal auditory evoked response and alpha-bungarotoxin-binding nicotinic cholinergic receptors in inbred mouse strains. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 15: 152-62. PMID 8840351 DOI: 10.1016/0893-133X(95)00178-G  0.34
1996 Nagamoto HT, Adler LE, Hea RA, Griffith JM, McRae KA, Freedman R. Gating of auditory P50 in schizophrenics: unique effects of clozapine. Biological Psychiatry. 40: 181-8. PMID 8830951 DOI: 10.1016/0006-3223(95)00371-1  0.381
1996 Harris JG, Adler LE, Young DA, Cullum CM, Rilling LM, Cicerello A, Intemann PM, Freedman R. Neuropsychological dysfunction in parents of schizophrenics. Schizophrenia Research. 20: 253-60. PMID 8827851 DOI: 10.1016/0920-9964(96)00009-6  0.343
1996 Young DA, Waldo M, Rutledge JH, Freedman R. Heritability of inhibitory gating of the p50 auditory-evoked potential in monozygotic and dizygotic twins Neuropsychobiology. 33: 113-117. PMID 8776738 DOI: 10.1159/000119260  0.367
1996 Ross RG, Hommer D, Radant A, Roath M, Freedman R. Early expression of smooth-pursuit eye movement abnormalities in children of schizophrenic parents. Journal of the American Academy of Child and Adolescent Psychiatry. 35: 941-9. PMID 8768356 DOI: 10.1097/00004583-199607000-00022  0.308
1996 Freedman R, Adler L, Cawthra E, Harris J, McRae K, Olincy A, Ross R, Sullivan B, Waldo M, Young D. Attention and sensory gating deficits in relatives of schizophrenic patients Biological Psychiatry. 39: 501. DOI: 10.1016/0006-3223(96)83956-4  0.327
1995 Waldo M, Myles-Worsley M, Madison A, Byerley W, Freedman R. Sensory gating deficits in parents of schizophrenics American Journal of Medical Genetics - Neuropsychiatric Genetics. 60: 506-511. PMID 8825886 DOI: 10.1002/Ajmg.1320600605  0.44
1995 Breese CR, Freedman R, Leonard SS. Glutamate receptor subtype expression in human postmortem brain tissue from schizophrenics and alcohol abusers Brain Research. 674: 82-90. PMID 7773698 DOI: 10.1016/0006-8993(94)01384-T  0.308
1995 Hershman KM, Freedman R, Bickford PC. GABAB antagonists diminish the inhibitory gating of auditory response in the rat hippocampus. Neuroscience Letters. 190: 133-6. PMID 7644122 DOI: 10.1016/0304-3940(95)11523-Y  0.307
1995 Fang N, Coon H, Hoff M, Holik J, Hadley D, Reimherr F, Wender P, Myles-Worsley M, Waldo M, Freedman R, Byerley W. Search for a schizophrenia susceptibility gene on chromosome 18 Psychiatric Genetics. 5: 31-35. PMID 7582878 DOI: 10.1097/00041444-199521000-00005  0.362
1995 Griffith J, Hoffer LD, Adler LE, Zerbe GO, Freedman R. Effects of sound intensity on a midlatency evoked response to repeated auditory stimuli in schizophrenic and normal subjects. Psychophysiology. 32: 460-6. PMID 7568640 DOI: 10.1111/J.1469-8986.1995.Tb02097.X  0.311
1995 Freedman R, Hall M, Adler LE, Leonard S. Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia. Biological Psychiatry. 38: 22-33. PMID 7548469 DOI: 10.1016/0006-3223(94)00252-X  0.41
1995 Myles-Worsley M, Yaw J, Coon H, Byerley W, Freedman R. P50 sensory gating in children of multiplex schizophrenia families Schizophrenia Research. 15: 44. DOI: 10.1016/0920-9964(95)95141-U  0.374
1994 Freedman R, Adler LE, Bickford P, Byerley W, Coon H, Cullum CM, Griffith JM, Harris JG, Leonard S, Miller C. Schizophrenia and nicotinic receptors. Harvard Review of Psychiatry. 2: 179-92. PMID 9384901 DOI: 10.3109/10673229409017136  0.477
1994 Griffith JM, Adler LE, Freedman R. Fine motor performance in schizophrenia. Neuropsychobiology. 29: 179-84. PMID 8047244 DOI: 10.1159/000119084  0.312
1994 Waldo MC, Cawthra E, Adler LE, Dubester S, Staunton M, Nagamoto H, Baker N, Madison A, Simon J, Scherzinger A, Drebing C, Gerhardt G, Freedman R. Auditory sensory gating, hippocampal volume, and catecholamine metabolism in schizophrenics and their siblings Schizophrenia Research. 12: 93-106. PMID 8043530 DOI: 10.1016/0920-9964(94)90067-1  0.408
1994 Issa F, Kirch DG, Gerhardt GA, Bartko JJ, Suddath RL, Freedman R, Wyatt RJ. A multidimensional approach to analysis of cerebrospinal fluid biogenic amines in schizophrenia: II. Correlations with psychopathology. Psychiatry Research. 52: 251-8. PMID 7991719 DOI: 10.1016/0165-1781(94)90070-1  0.373
1994 Issa F, Gerhardt GA, Bartko JJ, Suddath RL, Lynch M, Gamache PH, Freedman R, Wyatt RJ, Kirch DG. A multidimensional approach to analysis of cerebrospinal fluid biogenic amines in schizophrenia: I. Comparisons with healthy control subjects and neuroleptic-treated/unmedicated pairs analyses. Psychiatry Research. 52: 237-49. PMID 7991718 DOI: 10.1016/0165-1781(94)90069-8  0.408
1994 Coon H, Jensen S, Holik J, Hoff M, Myles-Worsley M, Reimherr F, Wender P, Waldo M, Freedman R, Leppert M, Byerley W. Genomic scan for genes predisposing to schizophrenia American Journal of Medical Genetics. 54: 59-71. PMID 7909992 DOI: 10.1002/Ajmg.1320540111  0.311
1994 Freedman R, Strömberg I, Nordström AL, Seiger A, Olson L, Bygdeman M, Wiesel FA, Granholm AC, Hoffer BJ. Neuronal development in embryonic brain tissue derived from schizophrenic women and grafted to animal hosts. Schizophrenia Research. 13: 259-70. PMID 7841140 DOI: 10.1016/0920-9964(94)90051-5  0.343
1994 Hall M, Freedman R, Adler LE, Leonard S. Decreased numbers of hipocampal nicotinic receptors in schizophrenia Biological Psychiatry. 35: 700. DOI: 10.1016/0006-3223(94)90965-2  0.438
1994 Griffith J, Hoffer LJ, Adler LE, Freedman R. Effects of sound intensity on auditory P50 gating in schizophrenics and normals Biological Psychiatry. 35: 630. DOI: 10.1016/0006-3223(94)90712-9  0.313
1993 Coon H, Plaetke R, Holik J, Hoff M, Myles-Worsley M, Waldo M, Freedman R, Byerley W. Use of a neurophysiological trait in linkage analysis of schizophrenia Biological Psychiatry. 34: 277-289. PMID 8399828 DOI: 10.1016/0006-3223(93)90085-R  0.416
1993 Cullum CM, Harris JG, Waldo MC, Smernoff E, Madison A, Nagamoto HT, Griffith J, Adler LE, Freedman R. Neurophysiological and neuropsychological evidence for attentional dysfunction in schizophrenia. Schizophrenia Research. 10: 131-41. PMID 8398945 DOI: 10.1016/0920-9964(93)90048-N  0.39
1993 Browning MD, Dudek EM, Rapier JL, Leonard S, Freedman R. Significant reductions in synapsin but not synaptophysin specific activity in the brains of some schizophrenics. Biological Psychiatry. 34: 529-35. PMID 8274580 DOI: 10.1016/0006-3223(93)90195-J  0.36
1993 Adler LE, Hoffer LD, Wiser A, Freedman R. Normalization of auditory physiology by cigarette smoking in schizophrenic patients. The American Journal of Psychiatry. 150: 1856-61. PMID 8238642 DOI: 10.1176/Ajp.150.12.1856  0.368
1993 Griffith JM, Waldo M, Adler LE, Freedman R. Normalization of auditory sensory gating in schizophrenic patients after a brief period for sleep Psychiatry Research. 49: 29-39. PMID 8140180 DOI: 10.1016/0165-1781(93)90028-F  0.326
1993 Leonard S, Rollins Y, Logel J, Drebing C, Dill D, Hall M, Freedman R. Neurochemistry/molecular biologyExpression of the α7 nicotinic acetylcholine receptor subunit in normal and schizophrenic postmortem brain Schizophrenia Research. 9: 223. DOI: 10.1016/0920-9964(93)90485-2  0.315
1993 Issa F, Gerhardt G, Bartko J, Suddath R, Lynch M, Gamache P, Freedman R, Wyatt R, Kirch D. Cerebrospinal fluid biogenic amines in schizophrenia: Multi-dimensional neurochemical and multivariate statistical approaches Schizophrenia Research. 9: 221. DOI: 10.1016/0920-9964(93)90480-7  0.369
1993 Cullum C, Harris J, Werner J, Waldo M, Smernoff E, Madison A, Nagamoto H, Adler L, Freedman R. Verbal learning dysfunction in schizophrenia Schizophrenia Research. 9: 173. DOI: 10.1016/0920-9964(93)90332-D  0.375
1993 Freedman R, Adler LE, Griffith J, Waldo M, Olson L, Miller C, Bickford P, Stevens K, Hall M, Leonard S. Desensitization of nicotinic receptors on inhibitory interneurons as a possible pathophysiological mechanism in schizophrenia Schizophrenia Research. 9: 156. DOI: 10.1016/0920-9964(93)90283-O  0.449
1993 Adler LE, Hoffer LJ, Griffith J, Waldo M, Wieser A, Freedman R. Normalization of deficient P50 auditory sensory gating in schizophrenic patients and their first degree relatives by nicotine Schizophrenia Research. 9: 153. DOI: 10.1016/0920-9964(93)90272-K  0.352
1992 Luntz-Leybman V, Bickford PC, Freedman R. Cholinergic gating of response to auditory stimuli in rat hippocampus. Brain Research. 587: 130-6. PMID 1525643 DOI: 10.1016/0006-8993(92)91437-J  0.331
1992 Waldo M, Gerhardt G, Baker N, Drebing C, Adler L, Freedman R. Auditory sensory gating and catecholamine metabolism in schizophrenic and normal subjects. Psychiatry Research. 44: 21-32. PMID 1461944 DOI: 10.1016/0165-1781(92)90066-C  0.358
1992 Adler LE, Hoffer LJ, Griffith J, Waldo MC, Freedman R. Normalization by nicotine of deficient auditory sensory gating in the relatives of schizophrenics. Biological Psychiatry. 32: 607-16. PMID 1450287 DOI: 10.1016/0006-3223(92)90073-9  0.443
1992 Miller CL, Bickford PC, Luntz-Leybman V, Adler LE, Gerhardt GA, Freedman R. Phencyclidine and auditory sensory gating in the hippocampus of the rat. Neuropharmacology. 31: 1041-8. PMID 1436386 DOI: 10.1016/0028-3908(92)90106-Y  0.303
1992 Freedman R, Strömberg I, Seiger A, Olson L, Nordström AL, Wiesel FA, Bygdeman M, Wetmore C, Palmer MR, Hoffer BJ. Initial studies of embryonic transplants of human hippocampus and cerebral cortex derived from schizophrenic women. Biological Psychiatry. 32: 1148-63. PMID 1362085 DOI: 10.1016/0006-3223(92)90194-5  0.309
1992 Myles-Worsley M, Dale P, Polloi A, Levy D, Freedman R, Byerley W. Eye Tracking Abnormalities in Two Micronesian Families with Schizophrenia Psychiatric Genetics. 2: 209-212. DOI: 10.1097/00041444-199203000-00005  0.379
1991 Nagamoto HT, Adler LE, Waldo MC, Griffith J, Freedman R. Gating of auditory response in schizophrenics and normal controls. Effects of recording site and stimulation interval on the P50 wave Schizophrenia Research. 4: 31-40. PMID 1848997 DOI: 10.1016/0920-9964(91)90007-E  0.313
1991 Waldo MC, Carey G, Myles-Worsley M, Cawthra E, Adler LE, Nagamoto HT, Wender P, Byerley W, Plaetke R, Freedman R. Codistribution of a sensory gating deficit and schizophrenia in multi-affected families Psychiatry Research. 39: 257-268. PMID 1798824 DOI: 10.1016/0165-1781(91)90092-4  0.446
1991 Baker NJ, Kirch DG, Waldo M, Bell J, Adler LE, Hattox S, Murphy R, Freedman R. Plasma homovanillic acid and prognosis in Schizophrenia Biological Psychiatry. 29: 192-196. PMID 1671646 DOI: 10.1016/0006-3223(91)90048-Q  0.357
1991 Freedman R, Waldo M, Bickford-Wimer P, Nagamoto H. Elementary neuronal dysfunctions in schizophrenia Schizophrenia Research. 4: 233-243. PMID 1645590 DOI: 10.1016/0920-9964(91)90035-P  0.456
1991 Freedman R. A VA national research symposium on schizophrenia Schizophrenia Research. 4: 67-69. DOI: 10.1016/0920-9964(91)90025-M  0.391
1990 Adler LE, Gerhardt GA, Franks R, Baker N, Nagamoto H, Drebing C, Freedman R. Sensory physiology and catecholamines in schizophrenia and mania. Psychiatry Research. 31: 297-309. PMID 2333360 DOI: 10.1016/0165-1781(90)90099-Q  0.42
1990 Baker NJ, Staunton M, Adler LE, Gerhardt GA, Drebing C, Waldo M, Nagamoto H, Freedman R. Sensory gating deficits in psychiatric inpatients: relation to catecholamine metabolites in different diagnostic groups. Biological Psychiatry. 27: 519-28. PMID 2310807 DOI: 10.1016/0006-3223(90)90443-6  0.373
1990 Bickford-Wimer PC, Nagamoto H, Johnson R, Adler LE, Egan M, Rose GM, Freedman R. Auditory sensory gating in hippocampal neurons: a model system in the rat. Biological Psychiatry. 27: 183-92. PMID 2294981 DOI: 10.1016/0006-3223(90)90648-L  0.322
1990 Adler LE, Waldo MC, Tatcher A, Cawthra E, Baker N, Freedman R. Lack of relationship of auditory gating defects to negative symptoms in schizophrenia Schizophrenia Research. 3: 131-138. PMID 2278977 DOI: 10.1016/0920-9964(90)90046-A  0.435
1989 Nagamoto HT, Adler LE, Waldo MC, Freedman R. Sensory gating in schizophrenics and normal controls: Effects of changing stimulation interval Biological Psychiatry. 25: 549-561. PMID 2920190 DOI: 10.1016/0006-3223(89)90215-1  0.364
1989 de la Garza R, Freedman R, Hoffer BJ. Kappa-bungarotoxin blockade of nicotine electrophysiological actions in cerebellar Purkinje neurons. Neuroscience Letters. 99: 95-100. PMID 2748023 DOI: 10.1016/0304-3940(89)90271-1  0.317
1989 de la Garza R, Freedman R, Hoffer J. Nicotine-induced inhibition of cerebellar Purkinje neurons: specific actions of nicotine and selective blockade by mecamylamine. Neuropharmacology. 28: 495-501. PMID 2725857 DOI: 10.1016/0028-3908(89)90085-3  0.32
1989 Nagamoto HT, Adler LE, Waldo MC, Freedman R. Sensory gating in schizophrenics and normal controls: Evidence for heterogeneity in schizophrenics Schizophrenia Research. 2: 86. DOI: 10.1016/0920-9964(89)90122-9  0.336
1989 Freedman R, Adler L, Bickford-Wimer P, Drebing C, Gerhardt G, Granholm A, Hoffer B, Nagamoto H, Olson L, Rose G, Waldo M. Candidate neuronal mechanisms for abnormal sensory gating in schizophrenia Schizophrenia Research. 2: 82. DOI: 10.1016/0920-9964(89)90118-7  0.415
1989 Staunton M, Waldo M, Cawthra E, Adler LE, Baker N, Nagomoto H, Freedman R. Auditory sensory gating in schizophrenics and their siblings Biological Psychiatry. 25. DOI: 10.1016/0006-3223(89)91549-7  0.302
1989 Nagamoto HT, Adler LE, Waldo MC, Freedman R. Sensory gating in schizophrenics and normal controls: Evidence for heterogeneity in schizophrenics Biological Psychiatry. 25. DOI: 10.1016/0006-3223(89)91534-5  0.336
1988 Waldo MC, Adler LE, Freedman R. Defects in auditory sensory gating and their apparent compensation in relatives of schizophrenics Schizophrenia Research. 1: 19-24. PMID 3154501 DOI: 10.1016/0920-9964(88)90035-7  0.303
1988 Parfitt KD, Freedman R, Bickford-Wimer PC. Electrophysiological effects of locally applied noradrenergic agents at cerebellar Purkinje neurons: receptor specificity. Brain Research. 462: 242-51. PMID 2847850 DOI: 10.1016/0006-8993(88)90552-5  0.3
1987 de la Garza R, McGuire TJ, Freedman R, Hoffer BJ. The electrophysiological effects of nicotine in the rat cerebellum: evidence for direct postsynaptic actions. Neuroscience Letters. 80: 303-8. PMID 3683986 DOI: 10.1016/0304-3940(87)90472-1  0.316
1987 Waldo MC, Graze K, Bender SdG, Adler LE, Freedman R. Premenstrual mood changes and gating of the auditory evoked potential Psychoneuroendocrinology. 12: 35-40. PMID 3588811 DOI: 10.1016/0306-4530(87)90020-5  0.304
1987 Baker N, Adler LE, Franks RD, Waldo M, Berry S, Nagamoto H, Muckle A, Freedman R. Neurophysiological assessment of sensory gating in psychiatric inpatients: Comparison between schizophrenia and other diagnoses Biological Psychiatry. 22: 603-617. PMID 3580435 DOI: 10.1016/0006-3223(87)90188-0  0.431
1987 Freedman R, Adler LE, Baker N, Waldo M, Mizner G. Candidate for inherited neurobiological dysfunction in schizophrenia Somatic Cell and Molecular Genetics. 13: 479-484. PMID 3455019 DOI: 10.1007/Bf01534952  0.427
1987 de la Garza R, McGuire TJ, Freedman R, Hoffer BJ. Selective antagonism of nicotine actions in the rat cerebellum with alpha-bungarotoxin. Neuroscience. 23: 887-91. PMID 3437995 DOI: 10.1016/0306-4522(87)90165-5  0.334
1987 Freedman R, Adler LE, Gerhardt GA, Waldo M, Baker N, Rose GM, Drebing C, Nagamoto H, Bickford-Wimer P, Franks R. Neurobiological studies of sensory gating in schizophrenia. Schizophrenia Bulletin. 13: 669-78. PMID 2894074 DOI: 10.1093/Schbul/13.4.669  0.457
1986 Waldo MC, Freedman R. Gating of auditory evoked responses in normal college students Psychiatry Research. 19: 233-239. PMID 3797550 DOI: 10.1016/0165-1781(86)90102-2  0.308
1986 Adler LE, Rose G, Freedman R. Neurophysiological studies of sensory gating in rats: effects of amphetamine, phencyclidine, and haloperidol. Biological Psychiatry. 21: 787-98. PMID 3730461 DOI: 10.1016/0006-3223(86)90244-1  0.32
1986 Waldo M, Adler L, Franks R, Baker N, Siegel C, Freedman R. Sensory gating and schizophrenia Biological Psychology. 23: 108. DOI: 10.1016/0301-0511(86)90143-2  0.429
1985 Adler LE, Waldo MC, Freedman R. Neurophysiologic studies of sensory gating in schizophrenia: Comparison of auditory and visual responses Biological Psychiatry. 20: 1284-1296. PMID 4063418 DOI: 10.1016/0006-3223(85)90113-1  0.34
1985 Kirch DG, Palmer MR, Egan M, Freedman R. Electrophysiological interactions between haloperidol and reduced haloperidol, and dopamine, norepinephrine and phencyclidine in rat brain Neuropharmacology. 24: 375-379. PMID 2862598 DOI: 10.1016/0028-3908(85)90021-8  0.302
1984 Siegel C, Waldo M, Mizner G, Adler LE, Freedman R. Deficits in Sensory Gating in Schizophrenic Patients and Their Relatives: Evidence Obtained With Auditory Evoked Responses Archives of General Psychiatry. 41: 607-612. PMID 6732421 DOI: 10.1001/Archpsyc.1984.01790170081009  0.4
1983 Freedman R, Kirch D, Bell J, Adler LE, Pecevich M, Pachtman E, Denver P. Clonidine treatment of schizophrenia. Double-blind comparison to placebo and neuroleptic drugs. Acta Psychiatrica Scandinavica. 65: 35-45. PMID 6138923 DOI: 10.1111/J.1600-0447.1982.Tb00819.X  0.392
1982 Palmer MR, Freedman R, Dunwiddie TV. Interactions of a neuroleptic drug (fluphenazine) with catecholamines in hippocampus. Psychopharmacology. 76: 122-9. PMID 6805021 DOI: 10.1007/Bf00435265  0.31
1981 Marwaha J, Hoffer BJ, Geller HM, Freedman R. Electrophysiologic interactions of antipsychotic drugs with central noradrenergic pathways. Psychopharmacology. 73: 126-33. PMID 6112771 DOI: 10.1007/Bf00429202  0.326
1979 Freedman R, Schwab PJ. Paranoid symptoms in patients on a general hospital psychiatric unit. Implications for diagnosis and treatment. Archives of General Psychiatry. 35: 387-90. PMID 727891 DOI: 10.1001/Archpsyc.1978.01770270137014  0.358
Low-probability matches (unlikely to be authored by this person)
1998 Frazier CJ, Rollins YD, Breese CR, Leonard S, Freedman R, Dunwiddie TV. Acetylcholine Activates an α-Bungarotoxin-Sensitive Nicotinic Current in Rat Hippocampal Interneurons, But Not Pyramidal Cells The Journal of Neuroscience. 18: 1187-1195. DOI: 10.1523/Jneurosci.18-04-01187.1998  0.299
1987 Freedman R, Adler LE, Waldo M. Gating of the auditory evoked potential in children and adults Psychophysiology. 24: 223-227. PMID 3602274 DOI: 10.1111/J.1469-8986.1987.Tb00282.X  0.299
1989 Adler LE, Nagamoto H, Waldo M, Tatcher A, Baker N, Freedman R. Negative symptoms and p50 auditory gating in medicated schizophrenic patients Biological Psychiatry. 25. DOI: 10.1016/0006-3223(89)91533-3  0.298
1999 Olincy A, Leonard S, Young DA, Sullivan B, Freedman R. Decreased bombesin peptide response to cigarette smoking in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 20: 52-9. PMID 9885785 DOI: 10.1016/S0893-133X(98)00053-0  0.298
1997 Breese CR, Adams C, Logel J, Drebing C, Rollins Y, Barnhart M, Sullivan B, Demasters BK, Freedman R, Leonard S. Comparison of the regional expression of nicotinic acetylcholine receptor alpha7 mRNA and [125I]-alpha-bungarotoxin binding in human postmortem brain. The Journal of Comparative Neurology. 387: 385-98. PMID 9335422 DOI: 10.1002/(Sici)1096-9861(19971027)387:3<385::Aid-Cne5>3.0.Co;2-X  0.297
1999 Myles-Worsley M, Coon H, McDowell J, Brenner C, Hoff M, Lind B, Bennett P, Freedman R, Clementz B, Byerley W. Linkage of a composite inhibitory phenotype to a chromosome 22q locus in eight Utah families. American Journal of Medical Genetics. 88: 544-50. PMID 10490714 DOI: 10.1002/(Sici)1096-8628(19991015)88:5<544::Aid-Ajmg20>3.0.Co;2-V  0.297
1987 Waldo MC, Roath M, Levine W, Freedman R. A model program to teach parenting skills to schizophrenic mothers Hospital and Community Psychiatry. 38: 1110-1112. PMID 3666702 DOI: 10.1176/Ps.38.10.1110  0.296
2019 Hood VL, Berger R, Freedman R, Law AJ. Transcription of PIK3CD in human brain and schizophrenia: Regulation by pro inflammatory cytokines. Human Molecular Genetics. PMID 31211828 DOI: 10.1093/Hmg/Ddz144  0.295
1986 Wang Y, Palmer M, Freedman R, Hoffer B, Mattson MV, Lessor RA, Rice KC, Jacobson AE. Antagonism of phencyclidine action by metaphit in rat cerebellar Purkinje neurons: an electrophysiological study. Proceedings of the National Academy of Sciences of the United States of America. 83: 2724-7. PMID 3458231 DOI: 10.1073/Pnas.83.8.2724  0.295
1996 Myles-Worsley M, Coon H, Byerley W, Waldo M, Young D, Freedman R. Developmental and genetic influences on the P50 sensory gating phenotype Biological Psychiatry. 39: 289-295. PMID 8645776 DOI: 10.1016/0006-3223(95)00134-4  0.294
1994 Coon H, Holik J, Hoff M, Reimherr F, Wender P, Myles-Worsley M, Waldo M, Freedman R, Byerley W. Analysis of chromosome 22 markers in nine schizophrenia pedigrees American Journal of Medical Genetics. 54: 72-79. PMID 7909993 DOI: 10.1002/Ajmg.1320540112  0.294
1993 Bickford PC, Luntz-Leybman V, Freedman R. Auditory sensory gating in the rat hippocampus: modulation by brainstem activity. Brain Research. 607: 33-8. PMID 8481808 DOI: 10.1016/0006-8993(93)91486-C  0.293
2006 Suarez BK, Duan J, Sanders AR, Hinrichs AL, Jin CH, Hou C, Buccola NG, Hale N, Weilbaecher AN, Nertney DA, Olincy A, Green S, Schaffer AW, Smith CJ, Hannah DE, ... ... Freedman R, et al. Genomewide linkage scan of 409 European-ancestry and African American families with schizophrenia: suggestive evidence of linkage at 8p23.3-p21.2 and 11p13.1-q14.1 in the combined sample. American Journal of Human Genetics. 78: 315-33. PMID 16400611 DOI: 10.1086/500272  0.293
2019 Hoffman MC, Hunter SK, D'Alessandro A, Noonan K, Wyrwa A, Freedman R. Interaction of maternal choline levels and prenatal Marijuana's effects on the offspring. Psychological Medicine. 1-11. PMID 31364525 DOI: 10.1017/S003329171900179X  0.293
1986 Wang Y, Palmer, Freedman R, Rice K, Lessor R, Jacobson A, Hoffer B. Electrophysiological interactions of isomers of cyclazocine with the phencyclidine antagonist metaphit in rat cerebellar Purkinje neurons. The Journal of Neuroscience. 6: 3189-3196. DOI: 10.1523/Jneurosci.06-11-03189.1986  0.292
2013 Lee SH, Ripke S, Neale BM, Faraone SV, Purcell SM, Perlis RH, Mowry BJ, Thapar A, Goddard ME, Witte JS, Absher D, Agartz I, Akil H, Amin F, ... ... Freedman R, et al. Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs. Nature Genetics. 45: 984-94. PMID 23933821 DOI: 10.1038/Ng.2711  0.289
2015 Ross RG, Hunter SK, Hoffman MC, McCarthy L, Chambers BM, Law AJ, Leonard S, Zerbe GO, Freedman R. Perinatal Phosphatidylcholine Supplementation and Early Childhood Behavior Problems: Evidence for CHRNA7 Moderation. The American Journal of Psychiatry. appiajp201515091188. PMID 26651393 DOI: 10.1176/Appi.Ajp.2015.15091188  0.288
1982 Bickford PC, Palmer MR, Hoffer BJ, Freedman R. Interactions between phencyclidine and cholinergic excitation of hippocampal pyramidal neurons. Neuropharmacology. 21: 729-32. PMID 7121744 DOI: 10.1016/0028-3908(82)90056-9  0.287
1981 Bickford PC, Palmer MR, Rice KC, Hoffer BJ, Freedman R. Electrophysiological effects of phencyclidine on rat hippocampal pyramidal neurons. Neuropharmacology. 20: 733-42. PMID 7279144 DOI: 10.1016/0028-3908(81)90221-5  0.287
2009 Mexal S, Berger R, Logel J, Ross RG, Freedman R, Leonard S. Erratum to: Differential Regulation of α7 Nicotinic Receptor Gene (CHRNA7) Expression in Schizophrenic Smokers Journal of Molecular Neuroscience. 40: 267-267. DOI: 10.1007/S12031-009-9303-7  0.286
1987 Kirch DG, Gerhardt GA, Shelton RC, Freedman R, Wyatt RJ. Effect of chronic nicotine administration on monoamine and monoamine metabolite concentrations in rat brain. Clinical Neuropharmacology. 10: 376-83. PMID 3503681 DOI: 10.1097/00002826-198708000-00009  0.286
2006 Hall MH, Schulze K, Rijsdijk F, Picchioni M, Ettinger U, Bramon E, Freedman R, Murray RM, Sham P. Heritability and reliability of P300, P50 and duration mismatch negativity. Behavior Genetics. 36: 845-57. PMID 16826459 DOI: 10.1007/S10519-006-9091-6  0.284
1998 Freedman R. 1. Basic and clinical approaches to the genetics of deficits in schizophrenia Biological Psychiatry. 43: S9. DOI: 10.1016/S0006-3223(98)90475-9  0.284
1980 Marwaha J, Palmer M, Hoffer B, Freedman R. Phencyclidine-induced depressions of cerebellar Purkinje neurons. Life Sciences. 26: 1509-15. PMID 7392800 DOI: 10.1016/0024-3205(80)90274-X  0.283
1995 Griffith JM, Freedman R. Normalization of the auditory P50 gating deficit of schizophrenic patients after non-REM but not REM sleep. Psychiatry Research. 56: 271-8. PMID 7568549 DOI: 10.1016/0165-1781(95)02516-Y  0.283
1984 Bickford PC, Mosimann WF, Hoffer BJ, Freedman R. Effects of the selective noradrenergic neurotoxin DSP4 on cerebellar Purkinje neuron electrophysiology. Life Sciences. 34: 731-41. PMID 6422177 DOI: 10.1016/0024-3205(84)90380-1  0.28
2002 Adams CE, Broide RS, Chen Y, Winzer-Serhan UH, Henderson TA, Leslie FM, Freedman R. Development of the alpha7 nicotinic cholinergic receptor in rat hippocampal formation. Brain Research. Developmental Brain Research. 139: 175-87. PMID 12480132 DOI: 10.1016/S0165-3806(02)00547-3  0.279
1980 Freedman R, Silverman MM, Schwab PJ. Patients' awareness of extrapyramidal reactions to neuroleptic drugs: possible evidence for the role of catecholamines in perception. Psychiatry Research. 1: 31-8. PMID 45127 DOI: 10.1016/0165-1781(79)90025-8  0.278
1979 Moises HC, Woodward DJ, Hoffer BJ, Freedman R. Interactions of norepinephrine with Purkinje cell responses to putative amino acid neurotransmitters applied by microiontophoresis. Experimental Neurology. 64: 493-515. PMID 223861 DOI: 10.1016/0014-4886(79)90227-9  0.278
1995 Miller CL, Freedman R. The activity of hippocampal interneurons and pyramidal cells during the response of the hippocampus to repeated auditory stimuli. Neuroscience. 69: 371-81. PMID 8552235 DOI: 10.1016/0306-4522(95)00249-I  0.278
1985 Bickford PC, Hoffer BJ, Freedman R. Interaction of norepinephrine with Purkinje cell responses to cerebellar afferent inputs in aged rats. Neurobiology of Aging. 6: 89-94. PMID 4022233 DOI: 10.1016/0197-4580(85)90023-5  0.277
1985 Sorensen SM, Hattox S, Johnson SW, Bickford P, Murphy R, Freedman R. Norepinephrine-dependent and independent mechanisms of persistent effects of amphetamine in rat cerebellum Life Sciences. 36: 2383-2389. PMID 3925266 DOI: 10.1016/0024-3205(85)90342-X  0.275
1987 Gratton A, Hoffer BJ, Freedman R. Electrophysiological effects of phencyclidine in the medial prefrontal cortex of the rat. Neuropharmacology. 26: 1275-83. PMID 3670556 DOI: 10.1016/0028-3908(87)90087-6  0.274
1975 Freedman R, Hoffer BJ. Phenothiazine antagonism of the noradrenergic inhibition of cerebellar Purkinje neurons. Journal of Neurobiology. 6: 277-88. PMID 171341 DOI: 10.1002/Neu.480060304  0.273
2022 Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, ... ... Freedman R, et al. Mapping genomic loci implicates genes and synaptic biology in schizophrenia. Nature. PMID 35396580 DOI: 10.1038/s41586-022-04434-5  0.273
1985 Jonsson G, Sundström E, Mefford I, Olson L, Johnson S, Freedman R, Hoffer B. Electrophysiological and neurochemical correlates of the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) on central catecholamine neurons in the mouse. Naunyn-Schmiedeberg's Archives of Pharmacology. 331: 1-6. PMID 3877877 DOI: 10.1007/Bf00498844  0.272
1981 Marwaha J, Freedman R, Hoffer B. Electrophysiological changes at a central noradrenergic synapse during thallium toxicosis. Toxicology and Applied Pharmacology. 56: 345-52. PMID 7222018 DOI: 10.1016/0041-008X(80)90067-8  0.27
1983 Johnson SW, Palmer MR, Freedman R. Effects of dopamine on spontaneous and evoked activity of caudate neurons Neuropharmacology. 22: 843-851. PMID 6621814 DOI: 10.1016/0028-3908(83)90130-2  0.269
1983 Sorensen S, Freedman R. Effects of alprazolam on the activity of rat cerebellar purkinje neurons: Evidence for mediation by norepinephrine Drug Development Research. 3: 555-560. DOI: 10.1002/Ddr.430030607  0.269
1989 Bell J, Bickford-Wimer PC, de la Garza R, Egan M, Freedman R. Increased central noradrenergic activity during benzodiazepine withdrawal: an electrophysiological study. Neuropharmacology. 27: 1187-90. PMID 3205385 DOI: 10.1016/0028-3908(88)90016-0  0.268
1993 Miller CL, Freedman R. Medial septal neuron activity in relation to an auditory sensory gating paradigm. Neuroscience. 55: 373-80. PMID 7690909 DOI: 10.1016/0306-4522(93)90506-B  0.268
1989 Boyajian CL, Bickford-Wimer P, Kim MB, Freedman R, Cooper DMF. Pertussis toxin lesioning of the nucleus caudate-putamen attenuates adenylate cyclase inhibition and alters neuronal electrophysiological activity. Brain Research. 495: 66-74. PMID 2505888 DOI: 10.1016/0006-8993(89)91218-3  0.267
1986 Johnson S, Hoffer B, Freedman R. Investigation of the failure of parenterally administered haloperidol to antagonize dopamine released from micropipettes in the caudate. The Journal of Neuroscience. 6: 572-580. DOI: 10.1523/Jneurosci.06-02-00572.1986  0.267
1991 Bickford-Wimer P, Kim M, Boyajian C, Cooper DM, Freedman R. Effects of pertussis toxin on caudate neuron electrophysiology: studies with dopamine D1 and D2 agonists. Brain Research. 533: 263-7. PMID 1981169 DOI: 10.1016/0006-8993(90)91348-K  0.267
1982 Sorensen SM, Johnson SW, Freedman R. Persistant effects of amphetamine on cerebellar Purkinje neurons following chronic administration Brain Research. 247: 365-371. PMID 6289985 DOI: 10.1016/0006-8993(82)91262-8  0.266
1990 Freedman R, Olson L, Hoffer BJ. Toxic effects of lead on neuronal development and function. Environmental Health Perspectives. 89: 27-33. PMID 2088752 DOI: 10.1289/Ehp.908927  0.266
1992 Hoffer BJ, Leenders KL, Young D, Gerhardt G, Zerbe GO, Bygdeman M, Seiger A, Olson L, Strömberg I, Freedman R. Eighteen-month course of two patients with grafts of fetal dopamine neurons for severe Parkinson's disease. Experimental Neurology. 118: 243-52. PMID 1306484 DOI: 10.1016/0014-4886(92)90181-O  0.265
1981 Palmer MR, Björklund H, Freedman R, Taylor DA, Marwaha J, Olson L, Seiger A, Hoffer BJ. Permanent impairment of spontaneous Purkinje cell discharge in cerebellar grafts caused by chronic lead exposure. Toxicology and Applied Pharmacology. 60: 431-40. PMID 7292481 DOI: 10.1016/0041-008X(81)90328-8  0.265
1987 Freedman R, Waldo M, Waldo CI, Wilson JR. Genetic influences on the effects of alcohol on auditory evoked potentials Alcohol. 4: 249-253. PMID 3620092 DOI: 10.1016/0741-8329(87)90019-X  0.265
1981 Marwaha J, Palmer M, Hoffer B, Freedman R, Rice KC, Paul S, Skolnick P. Differential electrophysiological and behavioral responses to optically active derivatives of phencyclidine. Naunyn-Schmiedeberg's Archives of Pharmacology. 315: 203-9. PMID 7219569 DOI: 10.1007/Bf00499836  0.264
1993 Jensen S, Plaetkea R, Holik J, Hoff M, Myles-Worsley M, Leppert M, Coon H, Vest K, Freedman R, Waldo M, Zhou QY, Litt M, Civelli O, Byerley W. Linkage analysis of schizophrenia: The D1 dopamine receptor gene and several flanking DNA markers Human Heredity. 43: 58-62. PMID 8514328 DOI: 10.1159/000154115  0.263
1986 Pang K, Johnson SW, Maayani S, Freedman R. Structure-activity relationships of phencyclidine derivatives in rat cerebellum Pharmacology, Biochemistry and Behavior. 24: 127-134. PMID 3945656 DOI: 10.1016/0091-3057(86)90055-9  0.263
1983 Leder R, Kirch D, Murphy R, Clay K, Freedman R. Partial resolution of tardive dyskinesia with treatment of co-existing thyrotoxicosis. The Canadian Journal of Psychiatry. 28: 134-136. PMID 6839282 DOI: 10.1177/070674378302800212  0.263
1997 Harris JG, Benetto L, Adler L, Freedman R. Learning and recall inefficiency in schizophrenia Schizophrenia Research. 24: 107. DOI: 10.1016/S0920-9964(97)82295-5  0.263
1984 Rose G, Pang K, Palmer M, Freedman R. Differential effects of phencyclidine upon hippocampal complex-spike and theta neurons Neuroscience Letters. 45: 141-146. PMID 6328373 DOI: 10.1016/0304-3940(84)90089-2  0.262
1996 Olincy A, Ross RG, Young DA, Roath M, Freedman R. Smooth pursuit eye movements after smoking in schizophrenic patients Biological Psychiatry. 39: 574. DOI: 10.1016/0006-3223(96)84201-6  0.26
1994 Pariseau C, Gregor P, Myles-Worsley M, Holik J, Hoff M, Waldo M, Freedman R, Coon H, Byerley W. Schizophrenia and glutamate receptor genes Psychiatric Genetics. 4: 161-165. PMID 7719702 DOI: 10.1097/00041444-199400430-00006  0.26
1997 Olincy A, Ross RG, Youngd DA, Freedman R. Age Diminishes Performance on an Antisaccade Eye Movement Task Neurobiology of Aging. 18: 483-489. PMID 9390774 DOI: 10.1016/S0197-4580(97)00109-7  0.259
1997 Adams CE, Freedman R. Nicotinic antagonist α-bungarotoxin binding to rat hippocampal neurons containing nitric oxide synthase Brain Research. 776: 111-116. PMID 9439802 DOI: 10.1016/S0006-8993(97)00978-5  0.259
1998 Gault J, Robinson M, Berger R, Drebing C, Logel J, Hopkins J, Moore T, Jacobs S, Meriwether J, Choi MJ, Kim EJ, Walton K, Buiting K, Davis A, Breese C, ... Freedman R, et al. Genomic organization and partial duplication of the human alpha7 neuronal nicotinic acetylcholine receptor gene (CHRNA7). Genomics. 52: 173-85. PMID 9782083 DOI: 10.1006/Geno.1998.5363  0.259
1989 Baker NJ, Drebing C, Gerhardt G, Adler LE, Nagamoto H, Freedman R. Stability of plasma catecholamine metabolites in outpatient schizophrenics Biological Psychiatry. 25: A177. DOI: 10.1016/0006-3223(89)91844-1  0.258
1993 Hall M, Zerbe L, Leonard S, Freedman R. Characterization of [3H]cytisine binding to human brain membrane preparations. Brain Research. 600: 127-33. PMID 8422580 DOI: 10.1016/0006-8993(93)90410-O  0.257
1981 Marwaha J, Hoffer B, Freedman R. Electrophysiological actions of neurotensin in rat cerebellum. Regulatory Peptides. 1: 115-25. PMID 7255763 DOI: 10.1016/0167-0115(80)90015-4  0.257
1980 Taylor D, Freedman R, Seiger A, Olson L, Hoffer BJ. Conditions for adrenergic hyperinnervation in hippocampus: II. Electrophysiological evidence from intraocular double grafts. Experimental Brain Research. 39: 289-99. PMID 7398824 DOI: 10.1007/Bf00237118  0.257
1990 Freedman R. Evoked response to repeated auditory stimuli. Biological Psychiatry. 28: 1065-1066. PMID 2289002 DOI: 10.1016/0006-3223(90)90609-6  0.256
1991 Kirch D, Suddath R, Gerhardt G, Issa F, Freedman R, Wyatt R. Analysis of cerebrospinal fluid monoamines in schizophrenic patients on and off neuroleptic treatment and compared with healthy controls Schizophrenia Research. 4: 349. DOI: 10.1016/0920-9964(91)90265-S  0.254
1988 Baker NJ, Adler LE, Waldo M, Gerhardt G, Drebing C, Cox B, Berry S, Phillips W, Freedman R. Reproducibility of the measurement of plasma noradrenergic and dopaminergic metabolites in normal subjects. Psychiatry Research. 23: 119-30. PMID 3363020 DOI: 10.1016/0165-1781(88)90001-7  0.254
1978 Taylor D, Seiger A, Freedman R, Olson L, Hoffer B. Electrophysiological analysis reinnervation of transplants in the anterior chamber of the eye by the autonomic ground plexus of the iris. Proceedings of the National Academy of Sciences of the United States of America. 75: 1009-12. PMID 273212 DOI: 10.1073/Pnas.75.2.1009  0.252
1984 Olsen HE, Biddinger JE, Freedman R, Marquardt JE. Interminable treatment in patients who appear healthy. Hospital & Community Psychiatry. 35: 710-5. PMID 6745878 DOI: 10.1176/Ps.35.7.710  0.252
1987 Bickford-Wimer PC, Parfitt K, Hoffer BJ, Freedman R. Desipramine and noradrenergic neurotransmission in aging: failure to respond in aged laboratory animals. Neuropharmacology. 26: 597-605. PMID 3037423 DOI: 10.1016/0028-3908(87)90153-5  0.251
2002 Freedman R. Long-term effects of early genetic influences on behavior. The New England Journal of Medicine. 347: 213-5. PMID 12124413 DOI: 10.1056/Nejmcibr021046  0.251
1989 Lindvall O, Rehncrona S, Brundin P, Gustavii B, Astedt B, Widner H, Lindholm T, Björklund A, Leenders KL, Rothwell JC, Frackowiak R, Marsden D, Johnels B, Steg G, Freedman R, et al. Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease. A detailed account of methodology and a 6-month follow-up. Archives of Neurology. 46: 615-31. PMID 2786405 DOI: 10.1001/Archneur.1989.00520420033021  0.25
1985 Olson L, Vanderhaeghen J, Freedman R, Henschen A, Hoffer B, Seiger ÅA. Combined grafts of the ventral tegmental area and nucleus accumbens in oculo. Histochemical and electrophysiological characterization. Experimental Brain Research. 59: 325-337. PMID 4029306 DOI: 10.1007/Bf00230912  0.25
1980 Marwaha J, Hoffer B, Pittman R, Freedman R. Age-related electrophysiological changes in rat cerebellum. Brain Research. 201: 85-97. PMID 7417842 DOI: 10.1016/0006-8993(80)90777-5  0.25
2013 Greenwood TA, Swerdlow NR, Gur RE, Cadenhead KS, Calkins ME, Dobie DJ, Freedman R, Green MF, Gur RC, Lazzeroni LC, Nuechterlein KH, Olincy A, Radant AD, Ray A, Schork NJ, et al. Genome-wide linkage analyses of 12 endophenotypes for schizophrenia from the Consortium on the Genetics of Schizophrenia. The American Journal of Psychiatry. 170: 521-32. PMID 23511790 DOI: 10.1176/Appi.Ajp.2012.12020186  0.249
1997 Ross RG, Harris J, Olincy A, Radant A, Adler L, Freedman R. Smooth pursuit eye movements in parents of schizophrenic probands; A most likely carrier approach Schizophrenia Research. 24: 244-245. DOI: 10.1016/S0920-9964(97)82703-X  0.248
1986 Bickford PC, Hoffer BJ, Freedman R. Diminished interaction of norepinephrine with climbing fiber inputs to cerebellar Purkinje neurons in aged Fischer 344 rats. Brain Research. 385: 405-10. PMID 3022875 DOI: 10.1016/0006-8993(86)91092-9  0.248
2016 Freedman R. Further Investigation of Ketamine. The American Journal of Psychiatry. 173: 761-2. PMID 27477135 DOI: 10.1176/Appi.Ajp.2016.16050581  0.248
1980 Olson L, Seiger A, Taylor D, Freedman R, Hoffer BJ. Conditions for adrenergic hyperinnervation in hippocampus: I. Histochemical evidence from intraocular double grafts. Experimental Brain Research. 39: 277-88. PMID 7398823 DOI: 10.1007/Bf00237117  0.247
1988 Bickford-Wimer PC, Miller JA, Freedman R, Rose GM. Age-related reduction in responses of rat hippocampal neurons to locally applied monoamines. Neurobiology of Aging. 9: 173-9. PMID 3374734 DOI: 10.1016/S0197-4580(88)80047-2  0.247
1979 Freedman R, Taylor DA, Seiger A, Olson L, Hoffer BJ. Seizures and related epileptiform activity in hippocampus transplanted to the anterior chamber of the eye: modulation by cholinergic and adrenergic input. Annals of Neurology. 6: 281-95. PMID 233411 DOI: 10.1002/Ana.410060402  0.246
2000 Adler LE, Cawthra E, Nagamoto HT, Olincy A, McRae KA, Waldo MC, Freedman R. 115. Confirmation of differing distribution of P50 ratios in schizophrenic patients vs controls Biological Psychiatry. 47. DOI: 10.1016/S0006-3223(00)00377-2  0.245
1983 Lubman A, Emrick C, Mosimann WF, freedman R. Altered Mood And Norepinephrine Metabolism Following Withdrawal From Alcohol Drug and Alcohol Dependence. 12: 3-13. PMID 6641496 DOI: 10.1016/0376-8716(83)90049-2  0.244
2008 Braff DL, Freedman R, Schork NJ, Gottesman II. Deconstructing Schizophrenia: An Overview of the Use of Endophenotypes in Order to Understand a Complex Disorder Focus. 6: 221-233. DOI: 10.1176/foc.6.2.foc221  0.243
2008 Braff DL, Freedman R. Clinically responsible genetic testing in neuropsychiatric patients: a bridge too far and too soon. The American Journal of Psychiatry. 165: 952-5. PMID 18676598 DOI: 10.1176/Appi.Ajp.2008.08050717  0.243
1987 Lindvall O, Backlund EO, Farde L, Sedvall G, Freedman R, Hoffer B, Nobin A, Seiger A, Olson L. Transplantation in Parkinson's disease: two cases of adrenal medullary grafts to the putamen. Annals of Neurology. 22: 457-68. PMID 3435067 DOI: 10.1002/Ana.410220403  0.243
2010 Sanders AR, Levinson DF, Duan J, Dennis JM, Li R, Kendler KS, Rice JP, Shi J, Mowry BJ, Amin F, Silverman JM, Buccola NG, Byerley WF, Black DW, Freedman R, et al. The Internet-based MGS2 control sample: self report of mental illness. The American Journal of Psychiatry. 167: 854-65. PMID 20516154 DOI: 10.1176/Appi.Ajp.2010.09071050  0.243
1981 Marwaha J, Hoffer BJ, Freedman R. Electrophysiologic evidence for histamine receptors in rat cerebellum. Experimental Neurology. 74: 285-92. PMID 6793381 DOI: 10.1016/0014-4886(81)90166-7  0.242
1987 Olson L, Strömberg I, Bygdeman M, Granholm AC, Hoffer B, Freedman R, Seiger A. Human fetal tissues grafted to rodent hosts: structural and functional observations of brain, adrenal and heart tissues in oculo. Experimental Brain Research. 67: 163-78. PMID 3305059 DOI: 10.1007/Bf00269464  0.24
1981 Marwaha J, Hoffer BJ, Freedman R. Changes in noradrenergic neurotransmission in rat cerebellum during aging. Neurobiology of Aging. 2: 95-8. PMID 6272145 DOI: 10.1016/0197-4580(81)90005-1  0.24
1995 Sydow O, Hansson P, Young D, Meyerson B, Backlund EO, Ebendal T, Farnebo LO, Freedman R, Hamberger B, Hoffer B, Seiger A, Strömberq I, Olson L. Long-term beneficial effects of adrenal medullary autografts supported by nerve growth factor in Parkinson's disease. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 2: 445-54. PMID 24283725 DOI: 10.1111/J.1468-1331.1995.Tb00154.X  0.24
1993 Stevens K, Freedman R, Rose G. Mouse strains with differing numbers of hippocampal α-bungarotoxin binding sites display varying ability to gate to paired auditory stimuli Schizophrenia Research. 9: 168. DOI: 10.1016/0920-9964(93)90320-I  0.24
1985 Johnson SW, Hoffer BJ, Baker R, Freedman R. Correlation of Purkinje neuron depression and hypnotic effects of ethanol in inbred strains of rats. Alcoholism, Clinical and Experimental Research. 9: 56-8. PMID 3887969 DOI: 10.1111/J.1530-0277.1985.Tb05050.X  0.236
2003 Leonard S, Freedman R. Recombination in a schizophrenic proband fails to exclude CHRNA7 at chromosome 15q14. Molecular Psychiatry. 8: 145-6. PMID 12610645 DOI: 10.1038/Sj.Mp.4001209  0.235
1993 Byerley W, Coon H, Hoff M, Holik J, Waldo M, Freedman R, Caron MG, Giros B. Human dopamine transporter gene not linked to schizophrenia in multigenerational pedigrees. Human Heredity. 43: 319-22. PMID 8406521 DOI: 10.1159/000154151  0.233
1991 Olson L, Backlund EO, Ebendal T, Freedman R, Hamberger B, Hansson P, Hoffer B, Lindblom U, Meyerson B, Strömberg I. Intraputaminal infusion of nerve growth factor to support adrenal medullary autografts in Parkinson's disease. One-year follow-up of first clinical trial. Archives of Neurology. 48: 373-81. PMID 2012510 DOI: 10.1001/Archneur.1991.00530160037011  0.233
1995 Adams CE, Freedman R. Localization of alphabungarotoxin binding to chemically-identified subtypes of rat hippocampal neurons Schizophrenia Research. 15: 25. DOI: 10.1016/0920-9964(95)95088-Q  0.232
1981 Sorensen S, Dunwiddie T, McClearn G, Freedman R, Hoffer B. Ethanol-induced depressions in cerebellar and hippocampal neurons of mice selectively bred for differences in ethanol sensitivity: An electrophysiological study Pharmacology, Biochemistry and Behavior. 14: 227-234. PMID 7193886 DOI: 10.1016/0091-3057(81)90248-3  0.23
1991 Nagel K, Adler LE, Bell J, Nagamoto HT, Freedman R. Lithium carbonate and mood disorder in recently detoxified alcoholics: a double-blind, placebo-controlled pilot study Alcoholism: Clinical and Experimental Research. 15: 978-981. PMID 1789394 DOI: 10.1111/J.1530-0277.1991.Tb05198.X  0.23
1985 Waldo M, Freedman R. Effects of movement, concentration and emotional state on suppression of auditory P50 waves Biological Psychology. 21: 269-270. DOI: 10.1016/0301-0511(85)90151-6  0.23
1982 Sorensen S, Carter D, Marwaha J, Baker R, Freedman R. Disinhibition of rat cerebellar Purkinje neurons from noradrenergic inhibition during rising blood ethanol. Journal of Studies On Alcohol. 42: 908-17. PMID 6174828 DOI: 10.15288/Jsa.1981.42.908  0.23
2012 Hunter SK, Mendoza JH, D'Anna K, Zerbe GO, McCarthy L, Hoffman C, Freedman R, Ross RG. Antidepressants may mitigate the effects of prenatal maternal anxiety on infant auditory sensory gating. The American Journal of Psychiatry. 169: 616-24. PMID 22581104 DOI: 10.1176/Appi.Ajp.2012.11091365  0.23
2019 Pacheco A, Berger R, Freedman R, Law AJ. A VNTR Regulates miR-137 Expression Through Novel Alternative Splicing and Contributes to Risk for Schizophrenia. Scientific Reports. 9: 11793. PMID 31409837 DOI: 10.1038/S41598-019-48141-0  0.23
1995 Byerley W, Hoff M, Hυlik J, Myles-Worsley M, Waldo M, Freedman R, Coon H. Linkage analysis between schizophrenia and index simple-sequence repeat loci for chromosome 21 Human Heredity. 45: 49-52. PMID 7896300 DOI: 10.1159/000154254  0.228
2017 Freedman R, Ross R. 114.3 Pursuing Perinatal Prevention of Psychosis in the Population Schizophrenia Bulletin. 43: S59-S59. DOI: 10.1093/Schbul/Sbx021.155  0.228
2009 Freedman R, Lewis DA, Michels R, Pine DS, Schultz SK, Tamminga CA, Andreasen NC, Brady KT, Brent DA, Brzustowicz L, Carter CS, Eisenberg L, Goldman H, Javitt DC, Leibenluft E, et al. Conflict of interest-- an issue for every psychiatrist. The American Journal of Psychiatry. 166: 274. PMID 19255048 DOI: 10.1176/Appi.Ajp.2009.09010093  0.228
1985 FREEDMAN R. Neurophysiological Correlates of Normal Cognition and Psychopathology American Journal of Psychiatry. 142: 646-647. DOI: 10.1176/Ajp.142.5.646  0.227
2019 Hoffman MC, Olincy A, D'Alessandro A, Reisz JA, Hansen KC, Hunter SK, Freedman R, Ross RG. Effects of phosphatidylcholine and betaine supplements on women's serum choline Journal of Nutrition & Intermediary Metabolism. 16: 100094. DOI: 10.1016/J.Jnim.2019.100094  0.226
2013 Freedman R, Lewis DA, Michels R, Pine DS, Schultz SK, Tamminga CA, Gabbard GO, Gau SS, Javitt DC, Oquendo MA, Shrout PE, Vieta E, Yager J. The initial field trials of DSM-5: new blooms and old thorns. The American Journal of Psychiatry. 170: 1-5. PMID 23288382 DOI: 10.1176/Appi.Ajp.2012.12091189  0.225
1987 FREEDMAN R. Psychiatry Update: American Psychiatric Association Annual Review, vol. 5 American Journal of Psychiatry. 144: 515-515. DOI: 10.1176/Ajp.144.4.515  0.225
2009 Freedman R. Genetic investigation of race and addiction. The American Journal of Psychiatry. 166: 967-8. PMID 19723792 DOI: 10.1176/Appi.Ajp.2009.09071018  0.224
2018 Saito S, Horinouchi T, Nakagami Y, Ii T, Sarkar S, McSweeney A, Yoshida L, Aniwattanapong D, Xin LM, Segrec N, Varbanov SV, Shams SF, Suzuki K, Mariano MPV, Tomlin SC, ... ... Freedman R, et al. Approaches to Suicide Prevention: Ideas and Models Presented by Japanese and International Early Career Psychiatrists. Psychiatry and Clinical Neurosciences. PMID 29989263 DOI: 10.1111/Pcn.12737  0.223
2019 Hunter SK, Hoffman MC, D'Alessandro A, Noonan K, Wyrwa A, Freedman R, Law AJ. Male fetus susceptibility to maternal inflammation: C-reactive protein and brain development. Psychological Medicine. 1-10. PMID 31787129 DOI: 10.1017/S0033291719003313  0.221
2017 Freedman R. The Treatment of Bipolar Disorder: Integrative Clinical Strategies and Future Directionsedited by André F. Carvalho and Eduard Vieta. New York, Oxford University Press, 2017, 528 pp., $64.95 (paperback). The American Journal of Psychiatry. 174: 1226. PMID 29191037 DOI: 10.1176/Appi.Ajp.2017.17090996  0.221
1985 FREEDMAN R. EEG and Evoked Potentials in Psychiatry and Behavioral Neurology American Journal of Psychiatry. 142: 381-381. DOI: 10.1176/Ajp.142.3.381  0.221
1993 Leonard S, Luthman D, Logel J, Luthman J, Antle C, Freedman R, Hoffer B. Acidic and basic fibroblast growth factor mRNAs are increased in striatum following MPTP-induced dopamine neurofiber lesion: assay by quantitative PCR. Brain Research. Molecular Brain Research. 18: 275-84. PMID 7686995 DOI: 10.1016/0169-328X(93)90090-C  0.22
2019 Hunter S, Camille Hoffman M, Freedman R. 23.3 TARGETING GENETIC AND ENVIRONMENTAL RISK FOR MENTAL ILLNESS IN THE WOMB Schizophrenia Bulletin. 45: S126-S127. DOI: 10.1093/Schbul/Sbz022.093  0.22
1974 Hobson JA, McCarley RW, Pivik RT, Freedman R. Selective firing by cat pontine brain stem neurons in desynchronized sleep. Journal of Neurophysiology. 37: 497-511. PMID 4827018 DOI: 10.1152/Jn.1974.37.3.497  0.22
1993 Leonard S, Logel J, Luthman D, Casanova M, Kirch D, Freedman R. Biological stability of mRNA isolated from human postmortem brain collections. Biological Psychiatry. 33: 456-66. PMID 8098224 DOI: 10.1016/0006-3223(93)90174-C  0.22
1974 Hobson JA, McCarley RW, Freedman R, Pivik RT. Time course of discharge rate changes by cat pontine brain stem neurons during sleep cycle. Journal of Neurophysiology. 37: 1297-1309. PMID 4436702 DOI: 10.1152/Jn.1974.37.6.1297  0.219
1987 FREEDMAN R. Towards a Comprehensive Model for Schizophrenic Disorders: Psychoanalytic Essays in Memory of Ping-Nie Pao, M.D American Journal of Psychiatry. 144: 1353-1354. DOI: 10.1176/Ajp.144.10.1353  0.219
2010 Howes D, Ohley W, Dorian P, Klock C, Freedman R, Schock R, Krizanac D, Holzer M. Rapid induction of therapeutic hypothermia using convective-immersion surface cooling: safety, efficacy and outcomes. Resuscitation. 81: 388-92. PMID 20122778 DOI: 10.1016/J.Resuscitation.2009.12.025  0.218
2003 Freedman R. Book Review Psychiatric Genetics and Genomics Edited by Peter McGuffin, Michael J. Owen, and Irving I. Gottesman. 472 pp., illustrated. Oxford, England, Oxford University Press, 2002. $89.50. 0-19-263148-9 New England Journal of Medicine. 349: 411-412. DOI: 10.1056/Nejm200307243490425  0.218
1993 Coon H, Hoff M, Holik J, Delisi LE, Crowe T, Freedman R, Shields G, Boccio AM, Lerman M, Gershon ES, Gejman PV, Leppert M, Byerley W. C to T nucleotide substitution in codon 713 of amyloid precursor protein gene not found in 86 unrelated schizophrenics from multiplex families American Journal of Medical Genetics. 48: 36-39. PMID 8102836 DOI: 10.1002/Ajmg.1320480109  0.214
2018 Freedman R, Brown AS, Cannon TD, Druss BG, Earls FJ, Escobar J, Hurd YL, Lewis DA, López-Jaramillo C, Luby J, Mayberg HS, Moffitt TE, Oquendo M, Perlis RH, Pine DS, et al. Can a Framework Be Established for the Safe Use of Ketamine? The American Journal of Psychiatry. appiajp201818030290. PMID 29656666 DOI: 10.1176/Appi.Ajp.2018.18030290  0.214
2013 Freedman R. Searching for more effective smoking cessation treatment. The American Journal of Psychiatry. 170: 818-20. PMID 23903328 DOI: 10.1176/Appi.Ajp.2013.13060758  0.212
1989 Drebing CJ, Freedman R, Waldo M, Gerhardt GA. Unconjugated methoxylated catecholamine metabolites in human saliva. Quantitation methodology and comparison with plasma levels. Biomedical Chromatography : Bmc. 3: 217-20. PMID 2804429 DOI: 10.1002/Bmc.1130030509  0.212
2020 Freedman R, Hunter SK, Law AJ, D'Alessandro A, Noonan K, Wyrwa A, Camille Hoffman M. Maternal choline and respiratory coronavirus effects on fetal brain development. Journal of Psychiatric Research. 128: 1-4. PMID 32474140 DOI: 10.1016/J.Jpsychires.2020.05.019  0.21
1989 Cawthra E, Nagel K, Adler LE, Staunton M, Baker N, Waldo M, Freedman R. A scale to measure psychomotor activity and mood during postacute alcohol and drug withdrawal Biological Psychiatry. 25. DOI: 10.1016/0006-3223(89)91747-2  0.21
2019 Freedman R, Hunter SK, Law AJ, Wagner BD, D'Alessandro A, Christians U, Noonan K, Wyrwa A, Hoffman MC. Higher Gestational Choline Levels in Maternal Infection Are Protective for Infant Brain Development. The Journal of Pediatrics. PMID 30879727 DOI: 10.1016/J.Jpeds.2018.12.010  0.21
2018 Arango C, Díaz-Caneja CM, McGorry PD, Rapoport J, Sommer IE, Vorstman JA, McDaid D, Marín O, Serrano-Drozdowskyj E, Freedman R, Carpenter W. Preventive strategies for mental health. The Lancet. Psychiatry. PMID 29773478 DOI: 10.1016/S2215-0366(18)30057-9  0.21
2020 Freedman R, Hunter SK, Noonan K, Wyrwa A, Christians U, Law AJ, Hoffman MC. Maternal Prenatal Depression in Pregnancies With Female and Male Fetuses and Developmental Associations With C-reactive Protein and Cortisol. Biological Psychiatry. Cognitive Neuroscience and Neuroimaging. PMID 33060035 DOI: 10.1016/J.Bpsc.2020.08.003  0.209
1979 Freedman R. Electrophysiology is not sufficient to determine neuromodulatory function Behavioral and Brain Sciences. 2: 425-426. DOI: 10.1017/S0140525X00063470  0.209
2009 Freedman R. Matching patients and providers across the United States. Psychiatric Services (Washington, D.C.). 60: 1293. PMID 19797364 DOI: 10.1176/Ps.2009.60.10.1293  0.209
2003 Kisley M, Polk S, Hunter S, Ross R, Levisohn P, Freedman R. Sensory gating in infants Schizophrenia Research. 60: 253. DOI: 10.1016/S0920-9964(03)80374-2  0.209
1983 Johnson SW, Freedman R, Sorensen SM. Effects of d-amphetamine withdrawal in rats and man American Journal of Psychiatry. 140: 953-954. PMID 6859334 DOI: 10.1176/Ajp.140.7.953  0.208
1977 Olson L, Freedman R, Seiger A, Hoffer B. Electrophysiology and cytology of hippocampal formation transplants in the anterior chamber of the eye. I. Intrinsic organization. Brain Research. 119: 87-106. PMID 830386 DOI: 10.1016/0006-8993(77)90093-2  0.208
1988 Lindvall O, Rehncrona S, Gustavii B, Brundin P, Astedt B, Widner H, Lindholm T, Björklund A, Leenders KL, Rothwell JC, Frackowiak R, Marsden CD, Johnels B, Steg G, Freedman R, et al. Fetal dopamine-rich mesencephalic grafts in Parkinson's disease. Lancet. 2: 1483-4. PMID 2904587 DOI: 10.1016/S0140-6736(88)90950-6  0.208
2010 Freedman R. The American Psychiatric Publishing Textbook of Psychopharmacology, Fourth Editionedited by SchatzbergAlan F. and NemeroffCharles B. . Washington, D.C. American Psychiatric Publishing, Inc., 2009, 1648pp., $285.00. American Journal of Psychiatry. 167: 478-478. DOI: 10.1176/Appi.Ajp.2010.10010012  0.207
1986 FREEDMAN R. Childhood Psychosis in the First Four Years of Life American Journal of Psychiatry. 143: 242-242. DOI: 10.1176/Ajp.143.2.242  0.207
2013 Freedman R. James H. Scully, Jr., M.D., medical director of the American Psychiatric Association, 2003-2013 American Journal of Psychiatry. 170: 1113. DOI: 10.1176/Appi.Ajp.2013.13060723  0.205
1994 Maes M, Lambrechts J, Suy E, Vandervorst C, Bosnians E, Roy A, Pollack S, Garvey MJ, Noyes R, Woodman C, Cook B, Meltzer H, Blockx P, Cosyns P, Calabrese J, ... ... Freedman R, et al. Subject Index Vol. 29, 1994 Neuropsychobiology. 29: 203-204. DOI: 10.1159/000119090  0.205
2008 Löwenberg-Doornbos J, Freedman R. Het Dolhuys: a museum of people with mental illness and their treatment. American Journal of Psychiatry. 165: 694-694. PMID 18519535 DOI: 10.1176/Appi.Ajp.2008.07121948  0.203
2016 Freedman R. Investigating Trauma as a Risk Factor for Psychosis. Schizophrenia Bulletin. PMID 27799359 DOI: 10.1093/Schbul/Sbw153  0.203
2016 Freedman R, Michels R. Dissecting the Brain Mechanisms of Violence. The American Journal of Psychiatry. 173: 213-4. PMID 26926125 DOI: 10.1176/Appi.Ajp.2016.16010009  0.203
2008 Freedman R. Book Review Coercion as Cure: A Critical History of Psychiatry By Thomas Szasz. 278 pp. New Brunswick, NJ, Transaction, 2007. $34.95. 978-0-7658-0379-5 New England Journal of Medicine. 358: 435-436. DOI: 10.1056/Nejmbkrev59060  0.203
2018 Freedman R. Alcohol Use in a Study of Phosphatidylcholine Supplementation in Pregnancy: Response to Bell and Ajula. The American Journal of Psychiatry. 175: 578-579. PMID 29869549 DOI: 10.1176/Appi.Ajp.2018.18020147R2  0.201
1988 Hoffer BJ, Rose G, Parfitt K, Freedman R, Bickford-Wimer PC. Age-related changes in cerebellar noradrenergic function. Annals of the New York Academy of Sciences. 515: 269-86. PMID 3364888 DOI: 10.1111/J.1749-6632.1988.Tb32996.X  0.2
2016 Freedman R. The Psychiatric Interview in Clinical Practice, Third Edition by Roger A. MacKinnon, M.D., Robert Michels, M.D., and Peter J. Buckley, M.D. Washington, D.C., American Psychiatric Association Publishing, 2016, 704 pp., $79.00 (hardcover). The American Journal of Psychiatry. 173: 541-2. PMID 27133414 DOI: 10.1176/Appi.Ajp.2016.16020233  0.195
2009 FREEDMAN R. Neurobiology of Mental Illness, 3rd ed.edited by Dennis S. Charney, M.D., and Eric J. Nestler, M.D., Ph.D. New York, Oxford University Press, 2008, 1,504 pp., $225.00. American Journal of Psychiatry. 166: 1072-1073. DOI: 10.1176/Appi.Ajp.2009.09060873  0.194
2009 FREEDMAN R. Textbook of Hospital Psychiatryedited by Steven S. Sharfstein, M.D., M.P.A. Deputy Editors: Faith B. Dickerson, Ph.D., M.P.H., and John M. Oldham, M.D., M.S. Washington, D.C., American Psychiatric Publishing, 2009, 528 pp., $125.00. American Journal of Psychiatry. 166: 1194-1195. DOI: 10.1176/Appi.Ajp.2009.09040581  0.194
2006 Freedman R, Leventhal BL. Robert J. Harmon, M.D. (1946-2006) Journal of the American Academy of Child & Adolescent Psychiatry. 45: 1270-1271. DOI: 10.1097/01.Chi.0000233205.58674.52  0.193
2006 FREEDMAN R. The Yellow House: Van Gogh, Gauguin, and Nine Turbulent Weeks in Arlesby Martin Gayford. New York, Little, Brown and Company, 2006, 352 pp., $24.99. American Journal of Psychiatry. 163: 2202-2202. DOI: 10.1176/Ajp.2006.163.12.2202  0.192
2007 Freedman R, Ross R, Michels R, Appelbaum P, Siever L, Binder R, Carpenter W, Friedman SH, Resnick P, Rosenbaum J. Psychiatrists, mental illness, and violence. The American Journal of Psychiatry. 164: 1315-7. PMID 17728413 DOI: 10.1176/Appi.Ajp.2007.07061013  0.192
1999 Stevens KE, Kem WR, Freedman R. Selective alpha 7 nicotinic receptor stimulation normalizes chronic cocaine-induced loss of hippocampal sensory inhibition in C3H mice. Biological Psychiatry. 46: 1443-50. PMID 10578459 DOI: 10.1016/S0006-3223(99)00200-0  0.191
1986 Freedman R. Sleep cycle generation: Testing the new hypotheses Behavioral and Brain Sciences. 9: 406-406. DOI: 10.1017/S0140525X0004629X  0.189
2008 Krystal JH, Carter CS, Geschwind D, Manji HK, March JS, Nestler EJ, Zubieta JK, Charney DS, Goldman D, Gur RE, Lieberman JA, Roy-Byrne P, Rubinow DR, Anderson SA, Barondes S, ... ... Freedman R, et al. It is time to take a stand for medical research and against terrorism targeting medical scientists. Biological Psychiatry. 63: 725-7. PMID 18371494 DOI: 10.1016/J.Biopsych.2008.03.005  0.189
2007 Tamminga CA, Michels R, Pine DS, Schultz SK, Lewis DA, Freedman R. 2007 In review American Journal of Psychiatry. 164: 1780-1783. PMID 22688277 DOI: 10.1176/Appi.Ajp.2007.07101620  0.189
2015 Freedman R. Shrinks: The Untold Story of Psychiatryby Jeffrey A. Lieberman, M.D., with Ogi Ogas. New York, Little, Brown and Company, 2015, 313 pp., $28.00. American Journal of Psychiatry. 172: 489-489. DOI: 10.1176/Appi.Ajp.2015.15030386  0.189
1989 Gerhardt GA, Drebing CJ, Stephen C, Freedman R. Direct determination of unconjugated HVA in human plasma filtrates by HPLC coupled with dual-electrode coulometric electrochemical detection. Biomedical Chromatography : Bmc. 3: 105-9. PMID 2765691 DOI: 10.1002/Bmc.1130030303  0.188
2017 Pine DS, Freedman R. Perspective on Selective Serotonin Reuptake Inhibitors in Children and Adolescents. The American Journal of Psychiatry. appiajp201717010042. PMID 28263661 DOI: 10.1176/Appi.Ajp.2017.17010042  0.186
2009 Freedman R. Learning to review. The Journal of Clinical Psychiatry. 70: 1599-600. PMID 20031100 DOI: 10.4088/Jcp.09Com05628Whi  0.186
2014 Freedman R. Computerization of the therapeutic task of working through. The American Journal of Psychiatry. 171: 388-90. PMID 24687192 DOI: 10.1176/Appi.Ajp.2014.14020168  0.185
2012 Freedman R. Oblivion: A Memoir of Hector Abadby Abad FaciolinceHéctor, translated by Anne McLean and Rosalind Harvey. Devon, United Kingdom, Old Street Publishing, 2010, 261 pp., $26.00. American Journal of Psychiatry. 169: 1324-1325. DOI: 10.1176/Appi.Ajp.2012.12030346  0.183
2010 Freedman R. Abrupt withdrawal of antidepressant treatment. The American Journal of Psychiatry. 167: 886-8. PMID 20693464 DOI: 10.1176/Appi.Ajp.2010.10050783  0.183
2016 Freedman R. Publishing what's important Acta Psychiatrica Scandinavica. 132: 417-418. DOI: 10.1111/Acps.12487  0.182
2018 Freedman R. AJP at 175: Remembering Our Past as We Envision Our Future. The American Journal of Psychiatry. 175: 1. PMID 29301421 DOI: 10.1176/Appi.Ajp.2017.17101137  0.181
1986 Gerhardt GA, Drebing CJ, Freedman R. Simultaneous determination of free homovanillic acid, (3-methoxy-4-hydroxyphenyl)ethylene glycol, and vanilmandelic acid in human plasma by high-performance liquid chromatography coupled with dual-electrode coulometric electrochemical detection. Analytical Chemistry. 58: 2879-83. PMID 3813021 DOI: 10.1021/Ac00126A067  0.181
2006 Freedman R. New in theJournal American Journal of Psychiatry. 163: 11-11. DOI: 10.1176/Appi.Ajp.163.1.11  0.18
2009 Pine DS, Freedman R. Child psychiatry growin' up. The American Journal of Psychiatry. 166: 4-7. PMID 19122010 DOI: 10.1176/Appi.Ajp.2008.08101493  0.179
2016 Wasser T, Richards M, Radhakrishnan R, Freedman R. The American Journal of Psychiatry Residents' Journal: Training the Next Generation of Academic Psychiatrists. The American Journal of Psychiatry. 173: 461-4. PMID 27133407 DOI: 10.1176/Appi.Ajp.2015.15101267  0.178
2019 Porter A, Hunter S, Johnson Z, Freedman R, Hoffman MC. 284: Outcomes of maternal stress as evaluated by the perceived stress scale American Journal of Obstetrics and Gynecology. 220: S201-S202. DOI: 10.1016/J.Ajog.2018.11.305  0.178
2006 Gabbard GO, Freedman R. Psychotherapy in the Journal: What's missing? American Journal of Psychiatry. 163: 182-184. PMID 16449467 DOI: 10.1176/Appi.Ajp.163.2.182  0.177
2011 Pine DS, Freedman R. Imaging a brighter future. The American Journal of Psychiatry. 168: 885-7. PMID 21890801 DOI: 10.1176/Appi.Ajp.2011.11050788  0.176
1988 FREEDMAN R. Some Simple Concepts and Models American Journal of Psychiatry. 145: 371-a-371. DOI: 10.1176/Ajp.145.3.371-A  0.175
2008 Freedman R. Coping, resilience, and outcome. The American Journal of Psychiatry. 165: 1505-6. PMID 19047327 DOI: 10.1176/Appi.Ajp.2008.08091439  0.168
2007 Freedman R. Pictures of Nothing: Abstract Art Since Pollock American Journal of Psychiatry. 164: 1919-1920. PMID 22688287 DOI: 10.1176/Appi.Ajp.2007.07101624  0.166
2006 Freedman R, Lewis DA, Michels R, Pine DS, Schultz SK, Tamminga C, Patterson SL, McIntyre JS, Goldman HH, Yudofsky SC, Hales RE, Rapaport MH, Hales D, Krajeski J, Kupfer DJ, et al. Conflict of interest, round 2. The American Journal of Psychiatry. 163: 1481-3. PMID 16946167 DOI: 10.1176/Appi.Ajp.163.9.1481  0.161
2015 Freedman R, Lewis DA, Michels R, Pine DS, Rush AJ, Schultz SK, Tamminga CA, Radhakrishnan R. 2015 in Review. The American Journal of Psychiatry. 172: 1179-81. PMID 26619771 DOI: 10.1176/Appi.Ajp.2015.15091218  0.159
1994 Maes M, Lambrechts J, Suy E, Vandervorst C, Bosnians E, Roy A, Pollack S, Garvey MJ, Noyes R, Woodman C, Cook B, Meltzer H, Blockx P, Cosyns P, Calabrese J, ... ... Freedman R, et al. Contents, Vol. 29, 1994 Neuropsychobiology. 29. DOI: 10.1159/000119079  0.158
2014 Kraemer HC, Freedman R. Computer AIDS for the diagnosis of anxiety and depression. The American Journal of Psychiatry. 171: 134-6. PMID 24500454 DOI: 10.1176/Appi.Ajp.2013.13111458  0.153
1997 Olincy A, Young DA, Freedman R. Increased levels of the nicotine metabolite cotinine in schizophrenic smokers compared to other smokers Schizophrenia Research. 24: 66. DOI: 10.1016/S0920-9964(97)82182-2  0.151
2021 Hoffman MC, Freedman R, Law AJ, Clark AM, Hunter SK. Maternal nutrients and effects of gestational COVID-19 infection on fetal brain development. Clinical Nutrition Espen. 43: 1-8. PMID 34024500 DOI: 10.1016/j.clnesp.2021.04.019  0.147
1993 Myles-Worsley M, Coon H, Elliot J, Freedman R. Genetic and developmental factors in P50 sensory gating and smooth pursuit eye movement: A normative study of young twins Schizophrenia Research. 9: 164. DOI: 10.1016/0920-9964(93)90308-6  0.131
2020 Li Y, Freedman R. Prospects for improving future mental health of children through prenatal maternal micronutrient supplementation in China. Pediatric Investigation. 4: 118-126. PMID 32851355 DOI: 10.1002/ped4.12199  0.125
2021 Freedman R, Hunter SK, Law AJ, Clark AM, Roberts A, Hoffman MC. Choline, folic acid, Vitamin D, and fetal brain development in the psychosis spectrum. Schizophrenia Research. PMID 33838984 DOI: 10.1016/j.schres.2021.03.008  0.121
2011 Brzustowicz L, Freedman R. Digging more deeply for genetic effects in psychiatric illness. The American Journal of Psychiatry. 168: 1017-20. PMID 21969044 DOI: 10.1176/Appi.Ajp.2011.11060928  0.119
2020 Hunter SK, Hoffman MC, McCarthy L, D'Alessandro A, Wyrwa A, Noonan K, Christians U, Nakimuli-Mpungu E, Zeisel SH, Law AJ, Freedman R. Black American Maternal Prenatal Choline, Offspring Gestational Age at Birth, and Developmental Predisposition to Mental Illness. Schizophrenia Bulletin. PMID 33184653 DOI: 10.1093/schbul/sbaa171  0.117
1988 Freedman R, Nagamoto H. Brain evoked potentials as predictors of risk. Recent Developments in Alcoholism : An Official Publication of the American Medical Society On Alcoholism, the Research Society On Alcoholism, and the National Council On Alcoholism. 6: 323-31. PMID 3363184 DOI: 10.1007/978-1-4615-7718-8_18  0.114
1983 Kirch D, Hattox S, Bell J, Murphy R, Freedman R. Plasma homovanillic acid and tardive dyskinesia during neuroleptic maintenance and withdrawal. Psychiatry Research. 9: 217-23. PMID 6137850 DOI: 10.1016/0165-1781(83)90046-X  0.109
2014 Diwadkar VA, Murphy ER, Freedman RR. Temporal sequencing of brain activations during naturally occurring thermoregulatory events. Cerebral Cortex (New York, N.Y. : 1991). 24: 3006-13. PMID 23787950 DOI: 10.1093/Cercor/Bht155  0.108
2005 Lipmanson RC, Davalos DB, Hood R, Freedman R, Ross RG. 65 EFFECTS OF PRENATAL EXPOSURE TO NICOTINE ON THE MISMATCH NEGATIVITY IN YOUNG INFANTS Journal of Investigative Medicine. 53: S89.2-S89. DOI: 10.2310/6650.2005.00005.64  0.098
2014 Freedman RR. Postmenopausal physiological changes. Current Topics in Behavioral Neurosciences. 21: 245-56. PMID 24929849 DOI: 10.1007/7854_2014_325  0.095
2003 Freedman R. Electrophysiological phenotypes. Methods in Molecular Medicine. 77: 215-25. PMID 12298371 DOI: 10.1385/1-59259-348-8:215  0.089
2013 Lin NU, Freedman RA, Ramakrishna N, Younger J, Storniolo AM, Bellon JR, Come SE, Gelman RS, Harris GJ, Henderson MA, Macdonald SM, Mahadevan A, Eisenberg E, Ligibel JA, Mayer EL, et al. A phase I study of lapatinib with whole brain radiotherapy in patients with Human Epidermal Growth Factor Receptor 2 (HER2)-positive breast cancer brain metastases. Breast Cancer Research and Treatment. 142: 405-14. PMID 24197661 DOI: 10.1007/S10549-013-2754-0  0.086
2014 Freedman RR. Menopausal hot flashes: mechanisms, endocrinology, treatment. The Journal of Steroid Biochemistry and Molecular Biology. 142: 115-20. PMID 24012626 DOI: 10.1016/j.jsbmb.2013.08.010  0.083
2021 Hunter SK, Hoffman MC, D'Alessandro A, Walker VK, Balser M, Noonan K, Law AJ, Freedman R. Maternal prenatal choline and inflammation effects on 4-year-olds' performance on the Wechsler Preschool and Primary Scale of Intelligence-IV. Journal of Psychiatric Research. 141: 50-56. PMID 34174557 DOI: 10.1016/j.jpsychires.2021.06.037  0.082
2021 Hunter SK, Hoffman MC, D'Alessandro A, Wyrwa A, Noonan K, Zeisel SH, Law AJ, Freedman R. Prenatal choline, cannabis, and infection, and their association with offspring development of attention and social problems through 4 years of age. Psychological Medicine. 1-10. PMID 33491615 DOI: 10.1017/S0033291720005061  0.082
2015 Wall TS, Wasmund SL, Freedman RA, Akoum NW, Page RL, Hamdan MH. "Vasovagal" response during ventricular fibrillation: incidence and implications. Pacing and Clinical Electrophysiology : Pace. 38: 376-82. PMID 25594678 DOI: 10.1111/pace.12562  0.081
1994 Olson L, Bäckman L, Ebendal T, Eriksdotter-Jönhagen M, Hoffer B, Humpel C, Freedman R, Giacobini M, Meyerson B, Nordberg A. Role of growth factors in degeneration and regeneration in the central nervous system; clinical experiences with NGF in Parkinson's and Alzheimer's diseases. Journal of Neurology. 242: S12-5. PMID 7699401 DOI: 10.1007/Bf00939233  0.081
2021 Freedman R, Hunter SK, Law AJ, Hoffman MC. Prenatal prevention of psychiatric illness and childhood development population-wide. World Psychiatry : Official Journal of the World Psychiatric Association (Wpa). 20: 226-227. PMID 34002528 DOI: 10.1002/wps.20853  0.08
1980 FREEDMAN R. Texas Symposium Reviews Kinetics of Psychiatric Drugs Contemporary Psychology: a Journal of Reviews. 25: 483-483. DOI: 10.1037/018251  0.078
2010 Freedman RR. Treatment of menopausal hot flashes with 5-hydroxytryptophan. Maturitas. 65: 383-5. PMID 20031347 DOI: 10.1016/j.maturitas.2009.11.025  0.077
2019 Hoffman MC, Olincy A, D'Alessandro A, Reisz JA, Hansen KC, Hunter SK, Freedman R, Ross RG. Effects of phosphatidylcholine and betaine supplements on women's serum choline. Journal of Nutrition & Intermediary Metabolism. 16. PMID 36330042 DOI: 10.1016/j.jnim.2019.100094  0.077
2013 Freedman R, Sahhar M, Curnow L, Lee J, Peters H. Receiving enzyme replacement therapy for a lysosomal storage disorder: a preliminary exploration of the experiences of young patients and their families. Journal of Genetic Counseling. 22: 517-32. PMID 23536258 DOI: 10.1007/s10897-013-9579-1  0.077
2006 Freedman RR. Hot flashes: behavioral treatments, mechanisms, and relation to sleep. The American Journal of Medicine. 124-30. PMID 16414337 DOI: 10.1016/j.amjmed.2005.09.046  0.074
2015 Dusetzina SB, Ellis S, Freedman RA, Conti RM, Winn AN, Chambers JD, Alexander GC, Huskamp HA, Keating NL. How Do Payers Respond to Regulatory Actions? The Case of Bevacizumab. Journal of Oncology Practice / American Society of Clinical Oncology. 11: 313-8. PMID 26060224 DOI: 10.1200/Jop.2015.004218  0.071
2005 Freedman RR. Pathophysiology and treatment of menopausal hot flashes. Seminars in Reproductive Medicine. 23: 117-25. PMID 15852197 DOI: 10.1055/s-2005-869479  0.068
2013 Freedman RS, McKinney R. Is conflict of interest becoming a challenge for institution-based institutional review boards? Clinical Cancer Research. 19: 4034-4039. PMID 23741065 DOI: 10.1158/1078-0432.CCR-13-0543  0.067
2003 Cohen M, Urban P, Christenson JT, Joseph DL, Freedman RJ, Miller MF, Ohman EM, Reddy RC, Stone GW, Ferguson JJ. Intra-aortic balloon counterpulsation in US and non-US centres: results of the Benchmark Registry. European Heart Journal. 24: 1763-70. PMID 14522572 DOI: 10.1016/J.Ehj.2003.07.002  0.066
2015 Cohen-Hozler M, Sorek G, Kerem J, Schless S, Freedman R, Rotem H, Schweitzer M, Katz-Leurer M. The Influence of Intense Combined Training on Upper Extremity Function in Children With Unilateral Cerebral Palsy: Does Initial Ability Matter? Physical and Occupational Therapy in Pediatrics. 1-12. DOI: 10.3109/01942638.2015.1108379  0.064
2015 Freedman R. The lyrical novel: Studies in Herman Hesse, Andre Gide, and Virginia Woolf The Lyrical Novel: Studies in Herman Hesse, Andre Gide, and Virginia Woolf. 1-294.  0.063
2017 Novik EI, Dwyer J, Morelli JK, Parekh A, Cho C, Pludwinski E, Shrirao A, Freedman RM, MacDonald JS, Jayyosi Z. Long-enduring primary hepatocyte-based co-cultures improve prediction of hepatotoxicity. Toxicology and Applied Pharmacology. PMID 28942002 DOI: 10.1016/J.Taap.2017.09.013  0.062
2006 Freedman RR, Benton MD, Genik RJ, Graydon FX. Cortical activation during menopausal hot flashes. Fertility and Sterility. 85: 674-8. PMID 16500337 DOI: 10.1016/j.fertnstert.2005.08.026  0.061
2015 Freedman RG, Jung HT, Zilberstein S. Temporal and object relations in unsupervised plan and activity recognition Aaai Fall Symposium - Technical Report. 51-59.  0.061
2011 Freedman RR, Kruger ML, Tancer ME. Escitalopram treatment of menopausal hot flashes. Menopause (New York, N.Y.). 18: 893-6. PMID 21540755 DOI: 10.1097/gme.0b013e31820ccae9  0.06
2015 Freedman R, Whitcraft CR, Lowe CG. Connectivity and movements of juvenile predatory fishes between discrete restored estuaries in southern California Marine Ecology Progress Series. 520: 191-201. DOI: 10.3354/Meps11109  0.06
2005 FREEDMAN R. THE RELIGIOUS RIGHT AND THE CARTER ADMINISTRATION The Historical Journal. 48: 231-260. DOI: 10.1017/S0018246X04004285  0.059
2016 Vaz-Luis I, Lin NU, Keating NL, Barry WT, Lii J, Burstein HJ, Winer EP, Freedman RA. Treatment of early-stage human epidermal growth factor 2-positive cancers among medicare enrollees: age and race strongly associated with non-use of trastuzumab. Breast Cancer Research and Treatment. PMID 27484879 DOI: 10.1007/S10549-016-3927-4  0.058
2003 Stone GW, Ohman EM, Miller MF, Joseph DL, Christenson JT, Cohen M, Urban PM, Reddy RC, Freedman RJ, Staman KL, Ferguson JJ. Contemporary utilization and outcomes of intra-aortic balloon counterpulsation in acute myocardial infarction: the benchmark registry. Journal of the American College of Cardiology. 41: 1940-5. PMID 12798561 DOI: 10.1016/S0735-1097(03)00400-5  0.058
2013 Dusetzina SB, Alexander GC, Freedman RA, Huskamp HA, Keating NL. Trends in co-prescribing of antidepressants and tamoxifen among women with breast cancer, 2004-2010. Breast Cancer Research and Treatment. 137: 285-96. PMID 23149465 DOI: 10.1007/S10549-012-2330-Z  0.058
2015 Freedman RG, Fukunaga A. Integration of Planning with plan recognition using classical planners (Extended Abstract) Aaai Fall Symposium - Technical Report. 48-50.  0.057
2002 Christenson JT, Cohen M, Ferguson JJ, Freedman RJ, Miller MF, Ohman EM, Reddy RC, Stone GW, Urban PM. Trends in intraaortic balloon counterpulsation complications and outcomes in cardiac surgery. The Annals of Thoracic Surgery. 74: 1086-90; discussion . PMID 12400750 DOI: 10.1016/S0003-4975(02)03854-7  0.057
1996 Flach K, Gerhardt G, Freedman R, Adler L. Sensory gating in a computer model of the CA3 neural network of the hippocampus Biological Psychiatry. 39: 630. DOI: 10.1016/0006-3223(96)84384-8  0.057
2013 Freedman RA, Pitcher B, Keating NL, Ballman KV, Mandelblatt J, Kornblith AB, Kimmick GG, Hurria A, Winer EP, Hudis CA, Cohen HJ, Muss HB. Cognitive function in older women with breast cancer treated with standard chemotherapy and capecitabine on Cancer and Leukemia Group B 49907 Breast Cancer Research and Treatment. 139: 607-616. PMID 23681403 DOI: 10.1007/s10549-013-2562-6  0.057
2002 Cohen M, Ferguson JJ, Freedman RJ, Miller MF, Reddy RC, Ohman EM, Stone GW, Christenson J, Joseph DL. Comparison of outcomes after 8 vs. 9.5 French size intra-aortic balloon counterpulsation catheters based on 9,332 patients in the prospective Benchmark registry. Catheterization and Cardiovascular Interventions : Official Journal of the Society For Cardiac Angiography & Interventions. 56: 200-6. PMID 12112913 DOI: 10.1002/Ccd.10188  0.056
2016 Shields H, Li J, Pelletier S, Wang H, Freedman R, Mamon H, Ng A, Freedman A, Come S, Avigan D, Huberman M, Recht A. Persistence of dysphagia and odynophagia after mediastinal radiation and chemotherapy in patients with lung cancer or lymphoma. Diseases of the Esophagus : Official Journal of the International Society For Diseases of the Esophagus / I.S.D.E. PMID 27247116 DOI: 10.1111/dote.12498  0.056
2014 Freedman RG, Jung HT, Grupen RA, Zilberstein S. How robots can recognize activities and plans using topic models Aaai Workshop - Technical Report. 22-28.  0.056
2015 Freedman RA. Treatment of Breast Cancer in the Elderly Current Oncology Reports. 17. DOI: 10.1007/s11912-015-0475-8  0.055
2015 Freedman R, Salmon D, Degener S, Phillips M. Using teaching videos in the adaptive cycles of teaching Literacy Research, Practice and Evaluation. 5: 125-147. DOI: 10.1108/S2048-045820150000005013  0.055
2021 Hunter SK, Hoffman MC, McCarthy L, D'Alessandro A, Wyrwa A, Noonan K, Christians U, Nakimuli-Mpungu E, Zeisel SH, Law AJ, Freedman R. Targeting Treatments to Health Disparities. Schizophrenia Bulletin. PMID 33940629 DOI: 10.1093/schbul/sbab051  0.054
2014 Freedman R. The Renaissance chanson goes digital: Digitalduchemin.org Early Music. 42: 567-578. DOI: 10.1093/em/cau108  0.053
2021 Hunter SK, Freedman R, Law AJ, Christians U, Holzman JBW, Johnson Z, Hoffman MC. Maternal corticosteroids and depression during gestation and decreased fetal heart rate variability. Neuroreport. PMID 34284445 DOI: 10.1097/WNR.0000000000001711  0.053
2014 Freedman RG, Jung HT, Zilberstein S. Plan and activity recognition from a topic modeling perspective Proceedings International Conference On Automated Planning and Scheduling, Icaps. 2014: 360-364.  0.053
2016 Freedman RA, Gelman RS, Wefel JS, Melisko ME, Hess KR, Connolly RM, Van Poznak CH, Niravath PA, Puhalla SL, Ibrahim N, Blackwell KL, Liu MC, Lowe A, Agar NY, Ryabin N, et al. Translational Breast Cancer Research Consortium (TBCRC) 022: A Phase II Trial of Neratinib for Patients With Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer and Brain Metastases. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. PMID 26834058 DOI: 10.1200/JCO.2015.63.0343  0.053
2015 Vaz-Luis I, Lin NU, Keating NL, Barry WT, Lii H, Winer EP, Freedman RA. Racial differences in outcomes for patients with metastatic breast cancer by disease subtype. Breast Cancer Research and Treatment. 151: 697-707. PMID 26022349 DOI: 10.1007/S10549-015-3432-1  0.052
2012 Branston SD, Matos CF, Freedman RB, Robinson C, Keshavarz-Moore E. Investigation of the impact of Tat export pathway enhancement on E. coli culture, protein production and early stage recovery. Biotechnology and Bioengineering. 109: 983-91. PMID 22125050 DOI: 10.1002/Bit.24384  0.052
2007 Freedman RR, Wasson S. Miniature hygrometric hot flash recorder. Fertility and Sterility. 88: 494-6. PMID 17445808 DOI: 10.1016/j.fertnstert.2006.11.184  0.052
2014 Vaz-Luis I, Keating NL, Lin NU, Lii H, Winer EP, Freedman RA. Duration and toxicity of adjuvant trastuzumab in older patients with early-stage breast cancer: A population-based study Journal of Clinical Oncology. 32: 927-934. PMID 24516021 DOI: 10.1200/JCO.2013.51.1261  0.051
2013 Epstein AE, DiMarco JP, Ellenbogen KA, Estes NA, Freedman RA, Gettes LS, Gillinov AM, Gregoratos G, Hammill SC, Hayes DL, Hlatky MA, Newby LK, Page RL, Schoenfeld MH, Silka MJ, et al. 2012 ACCF/AHA/HRS focused update incorporated into the ACCF/AHA/HRS 2008 guidelines for device-based therapy of cardiac rhythm abnormalities: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society. Circulation. 127: e283-352. PMID 23255456 DOI: 10.1161/Cir.0B013E318276Ce9B  0.05
2013 Hayes D, Freedman R, Curtis AB, Niebauer M, Neal Kay G, Dinerman J, Beau S. Prevalence of externalized conductors in Riata and Riata ST silicone leads: results from the prospective, multicenter Riata Lead Evaluation Study. Heart Rhythm : the Official Journal of the Heart Rhythm Society. 10: 1778-82. PMID 23994078 DOI: 10.1016/J.Hrthm.2013.08.030  0.05
2013 Lipkowitz MS, Freedman BI, Langefeld CD, Comeau ME, Bowden DW, Kao WH, Astor BC, Bottinger EP, Iyengar SK, Klotman PE, Freedman RG, Zhang W, Parekh RS, Choi MJ, Nelson GW, et al. Apolipoprotein L1 gene variants associate with hypertension-attributed nephropathy and the rate of kidney function decline in African Americans. Kidney International. 83: 114-20. PMID 22832513 DOI: 10.1038/Ki.2012.263  0.049
2016 Römer RA, Wells SA, Jimenez-Roldan JE, Bhattacharyya M, Vishweshwara S, Freedman RB. The flexibility and dynamics of protein disulphide-isomerase. Proteins. PMID 27616289 DOI: 10.1002/prot.25159  0.047
2015 Freedman R, Takeshita JY. Family planning in Taiwan: An experiment in social change Family Planning in Taiwan: An Experiment in Social Change. 1-501.  0.047
2014 Lenart BA, Freedman R, Van Thiel GS, Dhawan A, McGill KC, Basu S, Meyer JR, Provencher CM, Cole BJ, Romeo AA, Verma NN. Magnetic resonance imaging evaluation of normal glenoid length and width: an anatomic study. Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association. 30: 915-20. PMID 24813321 DOI: 10.1016/J.Arthro.2014.03.006  0.047
2013 Anand V, Freedman R, Minh CC. An insightful and robust approach for multi-Tool interpretation: Moving away from traditional black box methods Society of Petroleum Engineers - International Petroleum Technology Conference 2013, Iptc 2013: Challenging Technology and Economic Limits to Meet the Global Energy Demand. 3: 1698-1714.  0.047
2014 Freedman RA, Muss HB. Managing metastatic human epidermal growth factor receptor 2 (HER2)-positive breast cancer in the older patient Journal of Geriatric Oncology. 5: 2-7. PMID 24484711 DOI: 10.1016/j.jgo.2013.10.001  0.046
2014 Freedman RA. Trastuzumab-related cardiotoxicity among older patients with breast cancer: Chavez-MacGregor M, Zhang N, Buchholz TA, et al (Univ of Texas MD Anderson Cancer Ctr, Houston) J Clin Oncol 31:4222-4228, 2013 Breast Diseases. 26: 166-168. DOI: 10.1016/j.breastdis.2015.04.035  0.046
2010 Freedman RR. Objective or subjective measurement of hot flashes in clinical trials: quo vadis. Maturitas. 67: 99-100. PMID 20615637 DOI: 10.1016/j.maturitas.2010.06.011  0.045
1995 Freedman R. 5291137 Processing method and apparatus for processing spin echo in-phase and quadrature amplitudes from a pulsed nuclear magnetism tool and producing new output data to be recorded on an output record Magnetic Resonance Imaging. 13: XIII. DOI: 10.1016/0730-725X(95)90054-9  0.045
2016 Freedman RS, Cantor SB, Merriman KW, Edgerton ME. 2013 HIPAA Changes Provide Opportunities and Challenges for Researchers: Perspectives from a Cancer Center. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 22: 533-9. PMID 26832744 DOI: 10.1158/1078-0432.Ccr-15-2155  0.045
2015 Freedman RL, Lucas DN. MBRRACE-UK: saving lives, improving mothers' care - implications for anaesthetists. International Journal of Obstetric Anesthesia. 24: 161-73. PMID 25841640 DOI: 10.1016/j.ijoa.2015.03.004  0.043
2002 Winter J, Klappa P, Freedman RB, Lilie H, Rudolph R. Catalytic activity and chaperone function of human protein-disulfide isomerase are required for the efficient refolding of proinsulin. The Journal of Biological Chemistry. 277: 310-7. PMID 11694508 DOI: 10.1074/jbc.M107832200  0.043
2013 Caves MS, Derham BK, Jezek J, Freedman RB. Thermal inactivation of uricase (urate oxidase): mechanism and effects of additives. Biochemistry. 52: 497-507. PMID 23237426 DOI: 10.1021/bi301334w  0.043
2013 Freedman R. Listening to the Psalms among the Huguenots: Simon Goulart as music editor Psalms in the Early Modern World. 37-60.  0.043
2003 Freedman R. The Bush Administration and the Israeli-Palestinian Conflict: A Preliminary Evaluation American Foreign Policy Interests. 25: 505-512. DOI: 10.1080/725540741  0.043
2012 Matos CF, Branston SD, Albiniak A, Dhanoya A, Freedman RB, Keshavarz-Moore E, Robinson C. High-yield export of a native heterologous protein to the periplasm by the tat translocation pathway in Escherichia coli. Biotechnology and Bioengineering. 109: 2533-42. PMID 22539025 DOI: 10.1002/Bit.24535  0.043
2002 Sievert LL, Freedman RR, Garcia JZ, Foster JW, Romano Soriano MdC, Longcope C, Franz C. Measurement of hot flashes by sternal skin conductance and subjective hot flash report in Puebla, Mexico Menopause. 9: 367-376. PMID 12218726 DOI: 10.1097/00042192-200209000-00010  0.043
2016 Sagara Y, Freedman RA, Vaz-Luis I, Mallory MA, Wong SM, Aydogan F, DeSantis S, Barry WT, Golshan M. Patient Prognostic Score and Associations With Survival Improvement Offered by Radiotherapy After Breast-Conserving Surgery for Ductal Carcinoma In Situ: A Population-Based Longitudinal Cohort Study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 34: 1190-6. PMID 26834064 DOI: 10.1200/Jco.2015.65.1869  0.041
2017 Freedman RB, Desmond JL, Byrne LJ, Heal JW, Howard MJ, Sanghera N, Walker KL, Katrine Wallis A, Wells SA, Williamson RA, Römer RA. 'Something in the way she moves': The functional significance of flexibility in the multiple roles of protein disulfide isomerase (PDI). Biochimica Et Biophysica Acta. PMID 28844745 DOI: 10.1016/j.bbapap.2017.08.014  0.041
2016 Freedman R, McHangama J. Expanding or diluting human rights?: The proliferation of united nations special procedures mandates Human Rights Quarterly. 38: 164-193.  0.04
2011 Caves MS, Derham BK, Jezek J, Freedman RB. The mechanism of inactivation of glucose oxidase from Penicillium amagasakiense under ambient storage conditions. Enzyme and Microbial Technology. 49: 79-87. PMID 22112275 DOI: 10.1016/j.enzmictec.2011.03.004  0.04
2002 Freedman RR, Blacker CM. Estrogen raises the sweating threshold in postmenopausal women with hot flashes. Fertility and Sterility. 77: 487-90. PMID 11872200 DOI: 10.1016/s0015-0282(01)03009-6  0.04
Hide low-probability matches.