Giampietro Schiavo - Publications

Sobell Department of Motor Neuroscience and Motor Disorders UCL Institute of Neurology, Queen Square, London, England, United Kingdom 

211 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Vargas JNS, Sleigh JN, Schiavo G. Coupling axonal mRNA transport and local translation to organelle maintenance and function. Current Opinion in Cell Biology. 74: 97-103. PMID 35220080 DOI: 10.1016/  0.715
2022 Brown AL, Wilkins OG, Keuss MJ, Hill SE, Zanovello M, Lee WC, Bampton A, Lee FCY, Masino L, Qi YA, Bryce-Smith S, Gatt A, Hallegger M, Fagegaltier D, Phatnani H, ... ... Schiavo G, et al. TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A. Nature. PMID 35197628 DOI: 10.1038/s41586-022-04436-3  0.456
2021 Tosolini AP, Villarroel-Campos D, Schiavo G, Sleigh JN. Expanding the Toolkit for In Vivo Imaging of Axonal Transport. Journal of Visualized Experiments : Jove. PMID 35001910 DOI: 10.3791/63471  0.837
2021 Pirazzini M, Grinzato A, Corti D, Barbieri S, Leka O, Vallese F, Tonellato M, Silacci-Fregni C, Piccoli L, Kandiah E, Schiavo G, Zanotti G, Lanzavecchia A, Montecucco C. Exceptionally potent human monoclonal antibodies are effective for prophylaxis and treatment of tetanus in mice. The Journal of Clinical Investigation. 131. PMID 34618682 DOI: 10.1172/JCI151676  0.451
2021 Birsa N, Ule AM, Garone MG, Tsang B, Mattedi F, Chong PA, Humphrey J, Jarvis S, Pisiren M, Wilkins OG, Nosella ML, Devoy A, Bodo C, de la Fuente RF, Fisher EMC, ... ... Schiavo G, et al. FUS-ALS mutants alter FMRP phase separation equilibrium and impair protein translation. Science Advances. 7. PMID 34290090 DOI: 10.1126/sciadv.abf8660  0.794
2021 Villarroel-Campos D, Schiavo G, Sleigh JN. Dissection, in vivo imaging and analysis of the mouse epitrochleoanconeus muscle. Journal of Anatomy. PMID 34121181 DOI: 10.1111/joa.13478  0.644
2021 Mejia Maza A, Jarvis S, Lee WC, Cunningham TJ, Schiavo G, Secrier M, Fratta P, Sleigh JN, Fisher EMC, Sudre CH. NMJ-Analyser identifies subtle early changes in mouse models of neuromuscular disease. Scientific Reports. 11: 12251. PMID 34112844 DOI: 10.1038/s41598-021-91094-6  0.734
2021 Del Puerto A, Pose-Utrilla J, Simón-García A, López-Menéndez C, Jiménez AJ, Porlan E, Pajuelo LSM, Cano-García G, Martí-Prado B, Sebastián-Serrano Á, Sánchez-Carralero MP, Cesca F, Schiavo G, Ferrer I, Fariñas I, et al. Kidins220 deficiency causes ventriculomegaly via SNX27-retromer-dependent AQP4 degradation. Molecular Psychiatry. PMID 34002021 DOI: 10.1038/s41380-021-01127-9  0.673
2020 Lauwers E, Lalli G, Brandner S, Collinge J, Compernolle V, Duyckaerts C, Edgren G, Haïk S, Hardy J, Helmy A, Ivinson AJ, Jaunmuktane Z, Jucker M, Knight R, Lemmens R, ... ... Schiavo G, et al. Potential human transmission of amyloid β pathology: surveillance and risks. The Lancet. Neurology. 19: 872-878. PMID 32949547 DOI: 10.1016/S1474-4422(20)30238-6  0.679
2020 Sleigh JN, Mech AM, Aktar T, Zhang Y, Schiavo G. Altered Sensory Neuron Development in CMT2D Mice Is Site-Specific and Linked to Increased GlyRS Levels. Frontiers in Cellular Neuroscience. 14: 232. PMID 32848623 DOI: 10.3389/Fncel.2020.00232  0.739
2020 De La-Rocque S, Moretto E, Butnaru I, Schiavo G. Knockin' on heaven's door: Molecular mechanisms of neuronal tau uptake. Journal of Neurochemistry. PMID 32770783 DOI: 10.1111/Jnc.15144  0.322
2020 Stuardo N, Moya-Alvarado G, Ramírez C, Schiavo G, Bronfman FC. An Improved Protocol to Purify and Directly Mono-Biotinylate Recombinant BDNF in a Tube for Cellular Trafficking Studies in Neurons. Journal of Visualized Experiments : Jove. PMID 32716376 DOI: 10.3791/61262  0.726
2020 Sleigh JN, Mech AM, Schiavo G. Developmental demands contribute to early neuromuscular degeneration in CMT2D mice. Cell Death & Disease. 11: 564. PMID 32703932 DOI: 10.1038/S41419-020-02798-Y  0.691
2020 Sleigh JN, West SJ, Schiavo G. A video protocol for rapid dissection of mouse dorsal root ganglia from defined spinal levels. Bmc Research Notes. 13: 302. PMID 32580748 DOI: 10.1186/S13104-020-05147-6  0.703
2020 Mech AM, Brown AL, Schiavo G, Sleigh JN. Morphological variability is greater at developing than mature mouse neuromuscular junctions. Journal of Anatomy. PMID 32533580 DOI: 10.1111/Joa.13228  0.683
2020 Sleigh JN, Tosolini AP, Schiavo G. In Vivo Imaging of Anterograde and Retrograde Axonal Transport in Rodent Peripheral Nerves. Methods in Molecular Biology (Clifton, N.J.). 2143: 271-292. PMID 32524487 DOI: 10.1007/978-1-0716-0585-1_20  0.824
2020 Humphrey J, Birsa N, Milioto C, McLaughlin M, Ule AM, Robaldo D, Eberle AB, Kräuchi R, Bentham M, Brown AL, Jarvis S, Bodo C, Garone MG, Devoy A, Soraru G, ... ... Schiavo G, et al. FUS ALS-causative mutations impair FUS autoregulation and splicing factor networks through intron retention. Nucleic Acids Research. PMID 32479602 DOI: 10.1093/Nar/Gkaa410  0.773
2020 Sleigh JN, Tosolini AP, Gordon D, Devoy A, Fratta P, Fisher EMC, Talbot K, Schiavo G. Mice Carrying ALS Mutant TDP-43, but Not Mutant FUS, Display In Vivo Defects in Axonal Transport of Signaling Endosomes. Cell Reports. 30: 3655-3662.e2. PMID 32187538 DOI: 10.1016/J.Celrep.2020.02.078  0.82
2020 Rossor AM, Sleigh JN, Groves M, Muntoni F, Reilly MM, Hoogenraad CC, Schiavo G. Loss of BICD2 in muscle drives motor neuron loss in a developmental form of spinal muscular atrophy. Acta Neuropathologica Communications. 8: 34. PMID 32183910 DOI: 10.1186/S40478-020-00909-6  0.737
2020 Leese C, Bresnahan R, Doran C, Simsek D, Fellows AD, Restani L, Caleo M, Schiavo G, Mavlyutov T, Henke T, Binz T, Davletov B. Duplication of clostridial binding domains for enhanced macromolecular delivery into neurons. Toxicon: X. 5: 100019. PMID 32140681 DOI: 10.1016/j.toxcx.2019.100019  0.802
2020 Terenzio M, Di Pizio A, Rishal I, Marvaldi L, Di Matteo P, Kawaguchi R, Coppola G, Schiavo G, Fisher EMC, Fainzilber M. DYNLRB1 is essential for dynein mediated transport and neuronal survival. Neurobiology of Disease. 104816. PMID 32088381 DOI: 10.1016/J.Nbd.2020.104816  0.828
2020 Budzinska MI, Villarroel-Campos D, Golding M, Weston A, Collinson L, Snijders AP, Schiavo G. PTPN23 binds the dynein adaptor BICD1 and is required for endocytic sorting of neurotrophin receptors. Journal of Cell Science. PMID 32079660 DOI: 10.1242/Jcs.242412  0.411
2020 Fellows AD, Rhymes ER, Gibbs KL, Greensmith L, Schiavo G. IGF1R regulates retrograde axonal transport of signalling endosomes in motor neurons. Embo Reports. e49129. PMID 32030864 DOI: 10.15252/Embr.201949129  0.675
2019 Fratta P, Birsa N, Tosolini AP, Schiavo G. Travelling Together: A Unifying Pathomechanism for ALS. Trends in Neurosciences. PMID 31744630 DOI: 10.1016/J.Tins.2019.10.006  0.815
2019 Surana S, Villarroel-Campos D, Lazo OM, Moretto E, Tosolini AP, Rhymes ER, Richter S, Sleigh JN, Schiavo G. The evolution of the axonal transport toolkit. Traffic (Copenhagen, Denmark). PMID 31670447 DOI: 10.1111/Tra.12710  0.811
2019 Moretto E, Longatti A, Murru L, Chamma I, Sessa A, Zapata J, Hosy E, Sainlos M, Saint-Pol J, Rubinstein E, Choquet D, Broccoli V, Schiavo G, Thoumine O, Passafaro M. TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering. Cell Reports. 29: 1130-1146.e8. PMID 31665629 DOI: 10.1016/J.Celrep.2019.09.051  0.37
2019 Sleigh JN, Rossor AM, Fellows AD, Tosolini AP, Schiavo G. Axonal transport and neurological disease. Nature Reviews. Neurology. PMID 31558780 DOI: 10.1038/S41582-019-0257-2  0.827
2019 Sebastián-Serrano Á, Simón-García A, Belmonte-Alfaro A, Pose-Utrilla J, Santos-Galindo M, Del Puerto A, García-Guerra L, Hernández IH, Schiavo G, Campanero MR, Lucas JJ, Iglesias T. Differential regulation of kidins220 isoforms in Huntington's disease. Brain Pathology (Zurich, Switzerland). PMID 31264746 DOI: 10.1111/Bpa.12761  0.385
2019 Kalinski AL, Kar AN, Craver J, Tosolini AP, Sleigh JN, Lee SJ, Hawthorne A, Brito-Vargas P, Miller-Randolph S, Passino R, Shi L, Wong VSC, Picci C, Smith DS, Willis DE, ... ... Schiavo G, et al. Deacetylation of Miro1 by HDAC6 blocks mitochondrial transport and mediates axon growth inhibition. The Journal of Cell Biology. PMID 31068376 DOI: 10.1083/Jcb.201702187  0.807
2019 Vargas JNS, Wang C, Bunker E, Hao L, Maric D, Schiavo G, Randow F, Youle RJ. Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy. Molecular Cell. PMID 30853401 DOI: 10.1016/J.Molcel.2019.02.010  0.518
2019 Goto-Silva L, McShane MP, Salinas S, Kalaidzidis Y, Schiavo G, Zerial M. Retrograde transport of Akt by a neuronal Rab5-APPL1 endosome. Scientific Reports. 9: 2433. PMID 30792402 DOI: 10.1038/S41598-019-38637-0  0.482
2019 Cesca F, Schiavo G, Benfenati F. Kidins220/ARMS transgenic lines could be instrumental in the understanding of the molecular mechanisms leading to spastic paraplegia and obesity. European Journal of Neurology. 25: e107. PMID 30134048 DOI: 10.1111/Ene.13693  0.645
2018 Shorrock HK, van der Hoorn D, Boyd PJ, Llavero Hurtado M, Lamont DJ, Wirth B, Sleigh JN, Schiavo G, Wishart TM, Groen EJN, Gillingwater TH. UBA1/GARS-dependent pathways drive sensory-motor connectivity defects in spinal muscular atrophy. Brain : a Journal of Neurology. 141: 2878-2894. PMID 30239612 DOI: 10.1093/Brain/Awy237  0.701
2018 Villarroel-Campos D, Schiavo G, Lazo OM. The many disguises of the signalling endosome. Febs Letters. PMID 30176054 DOI: 10.1002/1873-3468.13235  0.762
2018 Gibbs KL, Kalmar B, Rhymes ER, Fellows AD, Ahmed M, Whiting P, Davies CH, Greensmith L, Schiavo G. Inhibiting p38 MAPK alpha rescues axonal retrograde transport defects in a mouse model of ALS. Cell Death & Disease. 9: 596. PMID 29789529 DOI: 10.1038/S41419-018-0624-8  0.664
2018 Clark AJ, Menendez G, AlQatari M, Patel N, Arstad E, Schiavo G, Koltzenburg M. Functional imaging in microfluidic chambers reveal sensory neuron sensitivity is differentially regulated between neuronal regions. Pain. PMID 29419650 DOI: 10.1097/J.Pain.0000000000001145  0.404
2017 Terenzio M, Schiavo G, Fainzilber M. Compartmentalized Signaling in Neurons: From Cell Biology to Neuroscience. Neuron. 96: 667-679. PMID 29096079 DOI: 10.1016/J.Neuron.2017.10.015  0.813
2017 Tyzack GE, Hall CE, Sibley CR, Cymes T, Forostyak S, Carlino G, Meyer IF, Schiavo G, Zhang SC, Gibbons GM, Newcombe J, Patani R, Lakatos A. A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models. Nature Communications. 8: 1164. PMID 29079839 DOI: 10.1038/S41467-017-01283-Z  0.375
2017 Surana S, Tosolini AP, Meyer IFG, Fellows AD, Novoselov SS, Schiavo G. The travel diaries of tetanus and botulinum neurotoxins. Toxicon : Official Journal of the International Society On Toxinology. PMID 29031941 DOI: 10.1016/J.Toxicon.2017.10.008  0.803
2017 Sleigh JN, Gómez-Martín A, Wei N, Bai G, Yang XL, Schiavo G. Neuropilin 1 sequestration by neuropathogenic mutant glycyl-tRNA synthetase is permissive to vascular homeostasis. Scientific Reports. 7: 9216. PMID 28835631 DOI: 10.1038/S41598-017-10005-W  0.677
2017 Kalmar B, Innes A, Wanisch K, Koyen Kolaszynska A, Pandraud A, Kelly G, Abramov AY, Reilly MM, Schiavo G, Greensmith L. Mitochondrial deficits and abnormal mitochondrial retrograde axonal transport play a role in the pathogenesis of mutant Hsp27 induced Charcot Marie Tooth Disease. Human Molecular Genetics. PMID 28595321 DOI: 10.1093/Hmg/Ddx216  0.639
2017 Sleigh JN, Dawes JM, West SJ, Wei N, Spaulding EL, Gómez-Martín A, Zhang Q, Burgess RW, Cader MZ, Talbot K, Yang XL, Bennett DL, Schiavo G. Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by Gars mutations. Proceedings of the National Academy of Sciences of the United States of America. PMID 28351971 DOI: 10.1073/Pnas.1614557114  0.76
2017 Sleigh JN, Vagnoni A, Twelvetrees AE, Schiavo G. Methodological advances in imaging intravital axonal transport. F1000research. 6: 200. PMID 28344778 DOI: 10.12688/F1000Research.10433.1  0.823
2016 Charlier CM, Debaisieux S, Foret C, Thouard A, Schiavo G, Gonzalez-Dunia D, Malnou CE. Neuronal retrograde transport of Borna disease virus occurs in signalling endosomes. The Journal of General Virology. 97: 3215-3224. PMID 27902378 DOI: 10.1099/Jgv.0.000652  0.441
2016 Zussy C, Loustalot F, Junyent F, Gardoni F, Bories C, Valero J, Desarménien MG, Bernex F, Henaff D, Bayo-Puxan N, Chen JW, Lonjon N, de Koninck Y, Malva JO, Bergelson JM, ... ... Schiavo G, et al. Coxsackievirus Adenovirus Receptor Loss Impairs Adult Neurogenesis, Synapse Content, and Hippocampus Plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 9558-9571. PMID 27629708 DOI: 10.1523/Jneurosci.0132-16.2016  0.334
2016 Twelvetrees AE, Pernigo S, Sanger A, Guedes-Dias P, Schiavo G, Steiner RA, Dodding MP, Holzbaur EL. The Dynamic Localization of Cytoplasmic Dynein in Neurons Is Driven by Kinesin-1. Neuron. PMID 27210554 DOI: 10.1016/J.Neuron.2016.04.046  0.826
2016 Ahmed M, Machado PM, Miller A, Spicer C, Herbelin L, He J, Noel J, Wang Y, McVey AL, Pasnoor M, Gallagher P, Statland J, Lu CH, Kalmar B, Brady S, ... ... Schiavo G, et al. Targeting protein homeostasis in sporadic inclusion body myositis. Science Translational Medicine. 8: 331ra41. PMID 27009270 DOI: 10.1126/Scitranslmed.Aad4583  0.547
2016 Sleigh JN, Weir GA, Schiavo G. A simple, step-by-step dissection protocol for the rapid isolation of mouse dorsal root ganglia. Bmc Research Notes. 9: 82. PMID 26864470 DOI: 10.1186/S13104-016-1915-8  0.704
2016 Debaisieux S, Encheva V, Chakravarty P, Snijders AP, Schiavo G. Analysis of Signaling Endosome Composition and Dynamics Using SILAC in Embryonic Stem Cell-Derived Neurons. Molecular & Cellular Proteomics : McP. 15: 542-57. PMID 26685126 DOI: 10.1074/Mcp.M115.051649  0.5
2016 Gibbs KL, Kalmar B, Sleigh JN, Greensmith L, Schiavo G. In vivo imaging of axonal transport in murine motor and sensory neurons. Journal of Neuroscience Methods. 257: 26-33. PMID 26424507 DOI: 10.1016/J.Jneumeth.2015.09.018  0.798
2016 Schiavo G, Meyer I, Novoselov S, Surana S, Tiknaz D, Tosolini A. Trafficking of tetanus and botulinum neurotoxins in the CNS Toxicon. 123: S75. DOI: 10.1016/J.Toxicon.2016.11.208  0.747
2015 Gibbs KL, Greensmith L, Schiavo G. Regulation of Axonal Transport by Protein Kinases. Trends in Biochemical Sciences. 40: 597-610. PMID 26410600 DOI: 10.1016/J.Tibs.2015.08.003  0.658
2015 Simão D, Pinto C, Fernandes P, Peddie CJ, Piersanti S, Collinson LM, Salinas S, Saggio I, Schiavo G, Kremer EJ, Brito C, Alves PM. Evaluation of helper-dependent canine adenovirus vectors in a 3D human CNS model. Gene Therapy. PMID 26181626 DOI: 10.1038/Gt.2015.75  0.337
2015 Schmieg N, Thomas C, Yabe A, Lynch DS, Iglesias T, Chakravarty P, Schiavo G. Novel Kidins220/ARMS Splice Isoforms: Potential Specific Regulators of Neuronal and Cardiovascular Development. Plos One. 10: e0129944. PMID 26083449 DOI: 10.1371/Journal.Pone.0129944  0.437
2015 Simão D, Pinto C, Piersanti S, Weston A, Peddie CJ, Bastos AE, Licursi V, Schwarz SC, Collinson LM, Salinas S, Serra M, Teixeira AP, Saggio I, Lima PA, Kremer EJ, ... Schiavo G, et al. Modeling human neural functionality in vitro: three-dimensional culture for dopaminergic differentiation. Tissue Engineering. Part A. 21: 654-68. PMID 25257211 DOI: 10.1089/Ten.Tea.2014.0079  0.323
2014 Bercsenyi K, Schmieg N, Bryson JB, Wallace M, Caccin P, Golding M, Zanotti G, Greensmith L, Nischt R, Schiavo G. Tetanus toxin entry. Nidogens are therapeutic targets for the prevention of tetanus. Science (New York, N.Y.). 346: 1118-23. PMID 25430769 DOI: 10.1126/Science.1258138  0.795
2014 Wang Y, Chakravarty P, Ranes M, Kelly G, Brooks PJ, Neilan E, Stewart A, Schiavo G, Svejstrup JQ. Dysregulation of gene expression as a cause of Cockayne syndrome neurological disease. Proceedings of the National Academy of Sciences of the United States of America. 111: 14454-9. PMID 25249633 DOI: 10.1073/Pnas.1412569111  0.302
2014 Terenzio M, Golding M, Russell MR, Wicher KB, Rosewell I, Spencer-Dene B, Ish-Horowicz D, Schiavo G. Bicaudal-D1 regulates the intracellular sorting and signalling of neurotrophin receptors. The Embo Journal. 33: 1582-98. PMID 24920579 DOI: 10.15252/Embj.201387579  0.761
2014 Terenzio M, Golding M, Schiavo G. siRNA screen of ES cell-derived motor neurons identifies novel regulators of tetanus toxin and neurotrophin receptor trafficking. Frontiers in Cellular Neuroscience. 8: 140. PMID 24904285 DOI: 10.3389/Fncel.2014.00140  0.789
2014 Garrett CA, Barri M, Kuta A, Soura V, Deng W, Fisher EM, Schiavo G, Hafezparast M. DYNC1H1 mutation alters transport kinetics and ERK1/2-cFos signalling in a mouse model of distal spinal muscular atrophy. Brain : a Journal of Neurology. 137: 1883-93. PMID 24755273 DOI: 10.1093/Brain/Awu097  0.585
2014 Hislop JN, Islam TA, Eleftheriadou I, Carpentier DC, Trabalza A, Parkinson M, Schiavo G, Mazarakis ND. Rabies virus envelope glycoprotein targets lentiviral vectors to the axonal retrograde pathway in motor neurons. The Journal of Biological Chemistry. 289: 16148-63. PMID 24753246 DOI: 10.1074/Jbc.M114.549980  0.469
2014 Salinas S, Zussy C, Loustalot F, Henaff D, Menendez G, Morton PE, Parsons M, Schiavo G, Kremer EJ. Disruption of the coxsackievirus and adenovirus receptor-homodimeric interaction triggers lipid microdomain- and dynamin-dependent endocytosis and lysosomal targeting. The Journal of Biological Chemistry. 289: 680-95. PMID 24273169 DOI: 10.1074/Jbc.M113.518365  0.467
2014 Schmieg N, Menendez G, Schiavo G, Terenzio M. Signalling endosomes in axonal transport: travel updates on the molecular highway. Seminars in Cell & Developmental Biology. 27: 32-43. PMID 24171925 DOI: 10.1016/J.Semcdb.2013.10.004  0.799
2014 Garrett C, Barri M, Kuta A, Soura V, Deng W, Fisher EE, Schiavo G, Hafezparast M. Defective axonal retrograde transport of signaling endosomes and MAP kinase signaling in a mouse model of autosomal dominant spinal muscular atrophy F1000research. 5. DOI: 10.7490/F1000Research.1096711.1  0.36
2013 Schiavo G, Greensmith L, Hafezparast M, Fisher EM. Cytoplasmic dynein heavy chain: the servant of many masters. Trends in Neurosciences. 36: 641-51. PMID 24035135 DOI: 10.1016/J.Tins.2013.08.001  0.689
2013 Ferrari E, Gu C, Niranjan D, Restani L, Rasetti-Escargueil C, Obara I, Geranton SM, Arsenault J, Goetze TA, Harper CB, Nguyen TH, Maywood E, O'Brien J, Schiavo G, Wheeler DW, et al. Synthetic self-assembling clostridial chimera for modulation of sensory functions. Bioconjugate Chemistry. 24: 1750-9. PMID 24011174 DOI: 10.1021/Bc4003103  0.803
2013 Goold R, McKinnon C, Rabbanian S, Collinge J, Schiavo G, Tabrizi SJ. Alternative fates of newly formed PrPSc upon prion conversion on the plasma membrane. Journal of Cell Science. 126: 3552-62. PMID 23813960 DOI: 10.1242/Jcs.120477  0.33
2013 Schiavo G, Fainzilber M. Cell biology: Alternative energy for neuronal motors. Nature. 495: 178-80. PMID 23486055 DOI: 10.1038/495178A  0.683
2013 Bercsenyi K, Giribaldi F, Schiavo G. The elusive compass of clostridial neurotoxins: deciding when and where to go? Current Topics in Microbiology and Immunology. 364: 91-113. PMID 23239350 DOI: 10.1007/978-3-642-33570-9_5  0.836
2013 Tighe AP, Schiavo G. Botulinum neurotoxins: mechanism of action. Toxicon : Official Journal of the International Society On Toxinology. 67: 87-93. PMID 23201505 DOI: 10.1016/J.Toxicon.2012.11.011  0.41
2013 Cogli L, Progida C, Thomas CL, Spencer-Dene B, Donno C, Schiavo G, Bucci C. Charcot-Marie-Tooth type 2B disease-causing RAB7A mutant proteins show altered interaction with the neuronal intermediate filament peripherin. Acta Neuropathologica. 125: 257-72. PMID 23179371 DOI: 10.1007/S00401-012-1063-8  0.42
2013 Schiavo G, Giribaldi F, Terenzio M, Golding M. Retrograde transport of proteins in the central nervous system Toxicon. 68: 70. DOI: 10.1016/J.Toxicon.2012.07.044  0.759
2013 Montecucco C, Megighian A, Pantano S, Rigoni M, Rossetto O, Schiavo G, Scorzeto M, Zanini D, Zordan M. Botulinum neurotoxins and the neuroexocytosis nanomachine Toxicon. 68: 62-63. DOI: 10.1016/J.Toxicon.2012.07.025  0.497
2012 Restani L, Giribaldi F, Manich M, Bercsenyi K, Menendez G, Rossetto O, Caleo M, Schiavo G. Botulinum neurotoxins A and E undergo retrograde axonal transport in primary motor neurons. Plos Pathogens. 8: e1003087. PMID 23300443 DOI: 10.1371/Journal.Ppat.1003087  0.82
2012 Rishal I, Kam N, Perry RB, Shinder V, Fisher EM, Schiavo G, Fainzilber M. A motor-driven mechanism for cell-length sensing. Cell Reports. 1: 608-16. PMID 22773964 DOI: 10.1016/J.Celrep.2012.05.013  0.718
2012 Scholz-Starke J, Cesca F, Schiavo G, Benfenati F, Baldelli P. Kidins220/ARMS is a novel modulator of short-term synaptic plasticity in hippocampal GABAergic neurons. Plos One. 7: e35785. PMID 22563401 DOI: 10.1371/Journal.Pone.0035785  0.705
2012 Neubrand VE, Cesca F, Benfenati F, Schiavo G. Kidins220/ARMS as a functional mediator of multiple receptor signalling pathways. Journal of Cell Science. 125: 1845-54. PMID 22562556 DOI: 10.1242/Jcs.102764  0.718
2012 Wade A, Thomas C, Kalmar B, Terenzio M, Garin J, Greensmith L, Schiavo G. Activated leukocyte cell adhesion molecule modulates neurotrophin signaling. Journal of Neurochemistry. 121: 575-86. PMID 22243278 DOI: 10.1111/J.1471-4159.2012.07658.X  0.831
2012 Cesca F, Yabe A, Spencer-Dene B, Scholz-Starke J, Medrihan L, Maden CH, Gerhardt H, Orriss IR, Baldelli P, Al-Qatari M, Koltzenburg M, Adams RH, Benfenati F, Schiavo G. Kidins220/ARMS mediates the integration of the neurotrophin and VEGF pathways in the vascular and nervous systems. Cell Death and Differentiation. 19: 194-208. PMID 22048155 DOI: 10.1038/Cdd.2011.141  0.703
2012 Kuta A, Hafezparast M, Schiavo G, Fisher EMC. Genetic insights into mammalian cytoplasmic dynein function provided by novel mutations in the mouse Dyneins. 482-503. DOI: 10.1016/B978-0-12-382004-4.10018-4  0.449
2011 Ferrari E, Maywood ES, Restani L, Caleo M, Pirazzini M, Rossetto O, Hastings MH, Niranjan D, Schiavo G, Davletov B. Re-assembled botulinum neurotoxin inhibits CNS functions without systemic toxicity. Toxins. 3: 345-55. PMID 22069712 DOI: 10.3390/Toxins3040345  0.797
2011 Cesca F, Yabe A, Spencer-Dene B, Arrigoni A, Al-Qatari M, Henderson D, Phillips H, Koltzenburg M, Benfenati F, Schiavo G. Kidins220/ARMS is an essential modulator of cardiovascular and nervous system development. Cell Death & Disease. 2: e226. PMID 22048169 DOI: 10.1038/Cddis.2011.108  0.722
2011 Sannerud R, Declerck I, Peric A, Raemaekers T, Menendez G, Zhou L, Veerle B, Coen K, Munck S, De Strooper B, Schiavo G, Annaert W. ADP ribosylation factor 6 (ARF6) controls amyloid precursor protein (APP) processing by mediating the endosomal sorting of BACE1. Proceedings of the National Academy of Sciences of the United States of America. 108: E559-68. PMID 21825135 DOI: 10.1073/Pnas.1100745108  0.339
2011 Malik B, Nirmalananthan N, Bilsland LG, La Spada AR, Hanna MG, Schiavo G, Gallo JM, Greensmith L. Absence of disturbed axonal transport in spinal and bulbar muscular atrophy. Human Molecular Genetics. 20: 1776-86. PMID 21317158 DOI: 10.1093/Hmg/Ddr061  0.653
2011 Granata A, Koo SJ, Haucke V, Schiavo G, Warner TT. CSN complex controls the stability of selected synaptic proteins via a torsinA-dependent process. The Embo Journal. 30: 181-93. PMID 21102408 DOI: 10.1038/Emboj.2010.285  0.338
2010 Bilsland LG, Sahai E, Kelly G, Golding M, Greensmith L, Schiavo G. Deficits in axonal transport precede ALS symptoms in vivo. Proceedings of the National Academy of Sciences of the United States of America. 107: 20523-8. PMID 21059924 DOI: 10.1073/Pnas.1006869107  0.654
2010 Salinas S, Schiavo G, Kremer EJ. A hitchhiker's guide to the nervous system: the complex journey of viruses and toxins. Nature Reviews. Microbiology. 8: 645-55. PMID 20706281 DOI: 10.1038/Nrmicro2395  0.468
2010 Neubrand VE, Thomas C, Schmidt S, Debant A, Schiavo G. Kidins220/ARMS regulates Rac1-dependent neurite outgrowth by direct interaction with the RhoGEF Trio. Journal of Cell Science. 123: 2111-23. PMID 20519585 DOI: 10.1242/Jcs.064055  0.427
2010 Terenzio M, Schiavo G. The more, the better: the BICD family gets bigger. The Embo Journal. 29: 1625-6. PMID 20485297 DOI: 10.1038/Emboj.2010.78  0.785
2010 Warner TT, Granata A, Schiavo G. TorsinA and DYT1 dystonia: a synaptopathy? Biochemical Society Transactions. 38: 452-6. PMID 20298201 DOI: 10.1042/Bst0380452  0.36
2010 Stevens JC, Chia R, Hendriks WT, Bros-Facer V, van Minnen J, Martin JE, Jackson GS, Greensmith L, Schiavo G, Fisher EM. Modification of superoxide dismutase 1 (SOD1) properties by a GFP tag--implications for research into amyotrophic lateral sclerosis (ALS). Plos One. 5: e9541. PMID 20221404 DOI: 10.1371/Journal.Pone.0009541  0.652
2010 Meunier FA, Nguyen TH, Colasante C, Luo F, Sullivan RK, Lavidis NA, Molgó J, Meriney SD, Schiavo G. Sustained synaptic-vesicle recycling by bulk endocytosis contributes to the maintenance of high-rate neurotransmitter release stimulated by glycerotoxin. Journal of Cell Science. 123: 1131-40. PMID 20215402 DOI: 10.1242/Jcs.049296  0.321
2009 Hammond GR, Schiavo G, Irvine RF. Immunocytochemical techniques reveal multiple, distinct cellular pools of PtdIns4P and PtdIns(4,5)P(2). The Biochemical Journal. 422: 23-35. PMID 19508231 DOI: 10.1042/Bj20090428  0.564
2009 Salinas S, Bilsland LG, Henaff D, Weston AE, Keriel A, Schiavo G, Kremer EJ. CAR-associated vesicular transport of an adenovirus in motor neuron axons. Plos Pathogens. 5: e1000442. PMID 19461877 DOI: 10.1371/Journal.Ppat.1000442  0.506
2009 Granata A, Schiavo G, Warner TT. TorsinA and dystonia: from nuclear envelope to synapse. Journal of Neurochemistry. 109: 1596-609. PMID 19457118 DOI: 10.1111/J.1471-4159.2009.06095.X  0.369
2009 Rinaldi S, Brennan KM, Goodyear CS, O'Leary C, Schiavo G, Crocker PR, Willison HJ. Analysis of lectin binding to glycolipid complexes using combinatorial glycoarrays. Glycobiology. 19: 789-96. PMID 19349623 DOI: 10.1093/Glycob/Cwp049  0.316
2009 Caleo M, Schiavo G. Central effects of tetanus and botulinum neurotoxins. Toxicon : Official Journal of the International Society On Toxinology. 54: 593-9. PMID 19264088 DOI: 10.1016/J.Toxicon.2008.12.026  0.608
2009 Ohka S, Sakai M, Bohnert S, Igarashi H, Deinhardt K, Schiavo G, Nomoto A. Receptor-dependent and -independent axonal retrograde transport of poliovirus in motor neurons. Journal of Virology. 83: 4995-5004. PMID 19244317 DOI: 10.1128/Jvi.02225-08  0.744
2008 Tooze SA, Schiavo G. Liaisons dangereuses: autophagy, neuronal survival and neurodegeneration. Current Opinion in Neurobiology. 18: 504-15. PMID 18840524 DOI: 10.1016/J.Conb.2008.09.015  0.44
2008 Salinas S, Bilsland LG, Schiavo G. Molecular landmarks along the axonal route: axonal transport in health and disease. Current Opinion in Cell Biology. 20: 445-53. PMID 18495455 DOI: 10.1016/J.Ceb.2008.04.002  0.501
2008 Granata A, Watson R, Collinson LM, Schiavo G, Warner TT. The dystonia-associated protein torsinA modulates synaptic vesicle recycling. The Journal of Biological Chemistry. 283: 7568-79. PMID 18167355 DOI: 10.1074/Jbc.M704097200  0.405
2007 Magnani E, Fan J, Gasparini L, Golding M, Williams M, Schiavo G, Goedert M, Amos LA, Spillantini MG. Interaction of tau protein with the dynactin complex. The Embo Journal. 26: 4546-54. PMID 17932487 DOI: 10.1038/Sj.Emboj.7601878  0.394
2007 Deinhardt K, Reversi A, Berninghausen O, Hopkins CR, Schiavo G. Neurotrophins Redirect p75NTR from a clathrin-independent to a clathrin-dependent endocytic pathway coupled to axonal transport. Traffic (Copenhagen, Denmark). 8: 1736-49. PMID 17897318 DOI: 10.1111/J.1600-0854.2007.00645.X  0.738
2007 Bowen S, Ateh DD, Deinhardt K, Bird MM, Price KM, Baker CS, Robson JC, Swash M, Shamsuddin W, Kawar S, El-Tawil T, Roos J, Hoyle A, Nickols CD, Knowles CH, ... ... Schiavo G, et al. The phagocytic capacity of neurones. The European Journal of Neuroscience. 25: 2947-55. PMID 17561810 DOI: 10.1111/J.1460-9568.2007.05554.X  0.769
2007 Hammond GR, Schiavo G. Polyphosphoinositol lipids: under-PPInning synaptic function in health and disease. Developmental Neurobiology. 67: 1232-47. PMID 17514716 DOI: 10.1002/Dneu.20509  0.582
2007 Kasperaviciute D, Weale ME, Shianna KV, Banks GT, Simpson CL, Hansen VK, Turner MR, Shaw CE, Al-Chalabi A, Pall HS, Goodall EF, Morrison KE, Orrell RW, Beck M, Jablonka S, ... ... Schiavo G, et al. Large-scale pathways-based association study in amyotrophic lateral sclerosis. Brain : a Journal of Neurology. 130: 2292-301. PMID 17439985 DOI: 10.1093/Brain/Awm055  0.512
2007 Salinas S, Carazo-Salas RE, Proukakis C, Schiavo G, Warner TT. Spastin and microtubules: Functions in health and disease. Journal of Neuroscience Research. 85: 2778-82. PMID 17348041 DOI: 10.1002/Jnr.21238  0.353
2007 Rigoni M, Pizzo P, Schiavo G, Weston AE, Zatti G, Caccin P, Rossetto O, Pozzan T, Montecucco C. Calcium influx and mitochondrial alterations at synapses exposed to snake neurotoxins or their phospholipid hydrolysis products. The Journal of Biological Chemistry. 282: 11238-45. PMID 17311918 DOI: 10.1074/Jbc.M610176200  0.527
2007 Bracale A, Cesca F, Neubrand VE, Newsome TP, Way M, Schiavo G. Kidins220/ARMS is transported by a kinesin-1-based mechanism likely to be involved in neuronal differentiation. Molecular Biology of the Cell. 18: 142-52. PMID 17079733 DOI: 10.1091/Mbc.E06-05-0453  0.732
2006 Schiavo G. Structural biology: dangerous liaisons on neurons. Nature. 444: 1019-20. PMID 17167419 DOI: 10.1038/Nature05410  0.377
2006 Deinhardt K, Salinas S, Verastegui C, Watson R, Worth D, Hanrahan S, Bucci C, Schiavo G. Rab5 and Rab7 control endocytic sorting along the axonal retrograde transport pathway. Neuron. 52: 293-305. PMID 17046692 DOI: 10.1016/J.Neuron.2006.08.018  0.752
2006 Deinhardt K, Berninghausen O, Willison HJ, Hopkins CR, Schiavo G. Tetanus toxin is internalized by a sequential clathrin-dependent mechanism initiated within lipid microdomains and independent of epsin1. The Journal of Cell Biology. 174: 459-71. PMID 16880274 DOI: 10.1083/Jcb.200508170  0.733
2006 Hammond GR, Dove SK, Nicol A, Pinxteren JA, Zicha D, Schiavo G. Elimination of plasma membrane phosphatidylinositol (4,5)-bisphosphate is required for exocytosis from mast cells. Journal of Cell Science. 119: 2084-94. PMID 16687737 DOI: 10.1242/Jcs.02912  0.574
2005 Rigoni M, Caccin P, Gschmeissner S, Koster G, Postle AD, Rossetto O, Schiavo G, Montecucco C. Equivalent effects of snake PLA2 neurotoxins and lysophospholipid-fatty acid mixtures. Science (New York, N.Y.). 310: 1678-80. PMID 16339444 DOI: 10.1126/Science.1120640  0.529
2005 Bohnert S, Schiavo G. Tetanus toxin is transported in a novel neuronal compartment characterized by a specialized pH regulation. The Journal of Biological Chemistry. 280: 42336-44. PMID 16236708 DOI: 10.1074/Jbc.M506750200  0.455
2005 Salinas S, Carazo-Salas RE, Proukakis C, Cooper JM, Weston AE, Schiavo G, Warner TT. Human spastin has multiple microtubule-related functions. Journal of Neurochemistry. 95: 1411-20. PMID 16219033 DOI: 10.1111/J.1471-4159.2005.03472.X  0.317
2005 Meunier FA, Osborne SL, Hammond GR, Cooke FT, Parker PJ, Domin J, Schiavo G. Phosphatidylinositol 3-kinase C2alpha is essential for ATP-dependent priming of neurosecretory granule exocytosis. Molecular Biology of the Cell. 16: 4841-51. PMID 16055506 DOI: 10.1091/Mbc.E05-02-0171  0.584
2005 Achilli F, Boyle S, Kieran D, Chia R, Hafezparast M, Martin JE, Schiavo G, Greensmith L, Bickmore W, Fisher EM. The SOD1 transgene in the G93A mouse model of amyotrophic lateral sclerosis lies on distal mouse chromosome 12. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 6: 111-4. PMID 16036435 DOI: 10.1080/14660820510035351  0.63
2005 Montecucco C, Schiavo G, Pantano S. SNARE complexes and neuroexocytosis: how many, how close? Trends in Biochemical Sciences. 30: 367-72. PMID 15935678 DOI: 10.1016/J.Tibs.2005.05.002  0.502
2005 Kieran D, Hafezparast M, Bohnert S, Dick JR, Martin J, Schiavo G, Fisher EM, Greensmith L. A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice. The Journal of Cell Biology. 169: 561-7. PMID 15911875 DOI: 10.1083/Jcb.200501085  0.706
2005 Parsons M, Monypenny J, Ameer-Beg SM, Millard TH, Machesky LM, Peter M, Keppler MD, Schiavo G, Watson R, Chernoff J, Zicha D, Vojnovic B, Ng T. Spatially distinct binding of Cdc42 to PAK1 and N-WASP in breast carcinoma cells. Molecular and Cellular Biology. 25: 1680-95. PMID 15713627 DOI: 10.1128/Mcb.25.5.1680-1695.2005  0.304
2005 Deinhardt K, Schiavo G. Endocytosis and retrograde axonal traffic in motor neurons. Biochemical Society Symposium. 139-50. PMID 15649138 DOI: 10.1042/Bss0720139  0.771
2005 Misbahuddin A, Placzek MR, Taanman JW, Gschmeissner S, Schiavo G, Cooper JM, Warner TT. Mutant torsinA, which causes early-onset primary torsion dystonia, is redistributed to membranous structures enriched in vesicular monoamine transporter in cultured human SH-SY5Y cells. Movement Disorders : Official Journal of the Movement Disorder Society. 20: 432-40. PMID 15593317 DOI: 10.1002/Mds.20351  0.387
2004 Montecucco C, Rossetto O, Schiavo G. Presynaptic receptor arrays for clostridial neurotoxins. Trends in Microbiology. 12: 442-6. PMID 15381192 DOI: 10.1016/J.Tim.2004.08.002  0.542
2004 Rigoni M, Schiavo G, Weston AE, Caccin P, Allegrini F, Pennuto M, Valtorta F, Montecucco C, Rossetto O. Snake presynaptic neurotoxins with phospholipase A2 activity induce punctate swellings of neurites and exocytosis of synaptic vesicles. Journal of Cell Science. 117: 3561-70. PMID 15226375 DOI: 10.1242/Jcs.01218  0.589
2004 Schiavo G, Chao MV. Motors, adaptors, and receptors: key elements of neuronal transport. Journal of Neurobiology. 58: 161-3. PMID 14704948 DOI: 10.1002/Neu.10325  0.59
2004 Hammond G, Thomas CL, Schiavo G. Nuclear phosphoinositides and their functions. Current Topics in Microbiology and Immunology. 282: 177-206. PMID 14594218 DOI: 10.1007/978-3-642-18805-3_7  0.581
2003 Lesa GM, Palfreyman M, Hall DH, Clandinin MT, Rudolph C, Jorgensen EM, Schiavo G. Long chain polyunsaturated fatty acids are required for efficient neurotransmission in C. elegans. Journal of Cell Science. 116: 4965-75. PMID 14625390 DOI: 10.1242/Jcs.00918  0.389
2003 Lalli G, Gschmeissner S, Schiavo G. Myosin Va and microtubule-based motors are required for fast axonal retrograde transport of tetanus toxin in motor neurons. Journal of Cell Science. 116: 4639-50. PMID 14576357 DOI: 10.1242/Jcs.00727  0.774
2003 Lalli G, Bohnert S, Deinhardt K, Verastegui C, Schiavo G. The journey of tetanus and botulinum neurotoxins in neurons. Trends in Microbiology. 11: 431-7. PMID 13678859 DOI: 10.1016/S0966-842X(03)00210-5  0.81
2003 Hafezparast M, Klocke R, Ruhrberg C, Marquardt A, Ahmad-Annuar A, Bowen S, Lalli G, Witherden AS, Hummerich H, Nicholson S, Morgan PJ, Oozageer R, Priestley JV, Averill S, King VR, ... ... Schiavo G, et al. Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science (New York, N.Y.). 300: 808-12. PMID 12730604 DOI: 10.1126/Science.1083129  0.791
2003 Caccin P, Rossetto O, Rigoni M, Johnson E, Schiavo G, Montecucco C. VAMP/synaptobrevin cleavage by tetanus and botulinum neurotoxins is strongly enhanced by acidic liposomes. Febs Letters. 542: 132-6. PMID 12729912 DOI: 10.1016/S0014-5793(03)00365-X  0.537
2002 Herreros J, Schiavo G. Lipid microdomains are involved in neurospecific binding and internalisation of clostridial neurotoxins. International Journal of Medical Microbiology : Ijmm. 291: 447-53. PMID 11890543 DOI: 10.1078/1438-4221-00152  0.409
2002 Lalli G, Schiavo G. Analysis of retrograde transport in motor neurons reveals common endocytic carriers for tetanus toxin and neurotrophin receptor p75NTR. The Journal of Cell Biology. 156: 233-9. PMID 11807088 DOI: 10.1083/Jcb.200106142  0.788
2002 Meunier FA, Schiavo G, Molgó J. Botulinum neurotoxins: from paralysis to recovery of functional neuromuscular transmission. Journal of Physiology, Paris. 96: 105-13. PMID 11755789 DOI: 10.1016/S0928-4257(01)00086-9  0.368
2002 Herreros J, Ng T, Schiavo G. Lipid rafts act as specialized domains for tetanus toxin binding and internalization into neurons. Molecular Biology of the Cell. 12: 2947-60. PMID 11598183 DOI: 10.1091/Mbc.12.10.2947  0.437
2001 Osborne SL, Meunier FA, Schiavo G. Phosphoinositides as key regulators of synaptic function. Neuron. 32: 9-12. PMID 11604134 DOI: 10.1016/S0896-6273(01)00455-X  0.323
2001 Kittler JT, Rostaing P, Schiavo G, Fritschy JM, Olsen R, Triller A, Moss SJ. The subcellular distribution of GABARAP and its ability to interact with NSF suggest a role for this protein in the intracellular transport of GABA(A) receptors. Molecular and Cellular Neurosciences. 18: 13-25. PMID 11461150 DOI: 10.1006/Mcne.2001.1005  0.621
2001 Rossetto O, Seveso M, Caccin P, Schiavo G, Montecucco C. Tetanus and botulinum neurotoxins: turning bad guys into good by research. Toxicon : Official Journal of the International Society On Toxinology. 39: 27-41. PMID 10936621 DOI: 10.1016/S0041-0101(00)00163-X  0.57
2000 Sinha K, Box M, Lalli G, Schiavo G, Schneider H, Groves M, Siligardi G, Fairweather N. Analysis of mutants of tetanus toxin Hc fragment: ganglioside binding, cell binding and retrograde axonal transport properties. Molecular Microbiology. 37: 1041-51. PMID 10972823 DOI: 10.1046/J.1365-2958.2000.02091.X  0.738
2000 Herreros J, Lalli G, Montecucco C, Schiavo G. Tetanus toxin fragment C binds to a protein present in neuronal cell lines and motoneurons. Journal of Neurochemistry. 74: 1941-50. PMID 10800937 DOI: 10.1046/J.1471-4159.2000.0741941.X  0.798
2000 Schiavo G, Matteoli M, Montecucco C. Neurotoxins affecting neuroexocytosis. Physiological Reviews. 80: 717-66. PMID 10747206 DOI: 10.1152/Physrev.2000.80.2.717  0.535
2000 Rossetto O, de Bernard M, Pellizzari R, Vitale G, Caccin P, Schiavo G, Montecucco C. Bacterial toxins with intracellular protease activity. Clinica Chimica Acta; International Journal of Clinical Chemistry. 291: 189-99. PMID 10675723 DOI: 10.1016/S0009-8981(99)00228-4  0.541
2000 HERREROS J, LALLI G, SCHIAVO G. C-terminal half of tetanus toxin fragment C is sufficient for neuronal binding and interaction with a putative protein receptor Biochemical Journal. 347: 199. DOI: 10.1042/0264-6021:3470199  0.738
1999 Müller JM, Rabouille C, Newman R, Shorter J, Freemont P, Schiavo G, Warren G, Shima DT. An NSF function distinct from ATPase-dependent SNARE disassembly is essential for Golgi membrane fusion. Nature Cell Biology. 1: 335-40. PMID 10559959 DOI: 10.1038/14025  0.326
1999 Owen DJ, Schiavo G. A handle on NSF Nature Cell Biology. 1. PMID 10559954 DOI: 10.1038/12959  0.318
1999 Schiavo G, Stenbeck G. Molecular analysis of neurotransmitter release. Essays in Biochemistry. 33: 29-41. PMID 10488439 DOI: 10.1042/Bse0330029  0.323
1999 Pellizzari R, Rossetto O, Schiavo G, Montecucco C. Tetanus and botulinum neurotoxins: mechanism of action and therapeutic uses. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 354: 259-68. PMID 10212474 DOI: 10.1098/Rstb.1999.0377  0.571
1999 Schiavo G, Lalli G, Herreros J. The bacterial toxin bible Trends in Microbiology. 7: 383. DOI: 10.1016/S0966-842X(99)01572-3  0.719
1998 Stamnes M, Schiavo G, Stenbeck G, Söllner TH, Rothman JE. ADP-ribosylation factor and phosphatidic acid levels in Golgi membranes during budding of coatomer-coated vesicles. Proceedings of the National Academy of Sciences of the United States of America. 95: 13676-80. PMID 9811859 DOI: 10.1073/Pnas.95.23.13676  0.515
1998 Montecucco C, Pellizzari R, Rossetto O, Schiavo G, Tonello F. Mechanism of action of clostridial neurotoxins Toxicology Letters. 95: 10. DOI: 10.1016/S0378-4274(98)80038-6  0.464
1997 Tonello F, Schiavo G, Montecucco C. Metal substitution of tetanus neurotoxin. The Biochemical Journal. 507-10. PMID 9065770 DOI: 10.1042/Bj3220507  0.475
1997 Schiavo G, Stenbeck G, Rothman JE, Söllner TH. Binding of the synaptic vesicle v-SNARE, synaptotagmin, to the plasma membrane t-SNARE, SNAP-25, can explain docked vesicles at neurotoxin-treated synapses. Proceedings of the National Academy of Sciences of the United States of America. 94: 997-1001. PMID 9023371 DOI: 10.1073/Pnas.94.3.997  0.524
1997 Montecucco C, Papini E, Schiavo G. Bacterial protein toxins and cell vesicle trafficking. Experientia. 52: 1026-32. PMID 8988242 DOI: 10.1007/Bf01952098  0.544
1997 Montecucco C, Schiavo G, Tugnoli V, de Grandis D. Botulinum neurotoxins: mechanism of action and therapeutic applications. Molecular Medicine Today. 2: 418-24. PMID 8897436 DOI: 10.1016/1357-4310(96)84845-3  0.561
1996 Schiavo G, Gu QM, Prestwich GD, Söllner TH, Rothman JE. Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin. Proceedings of the National Academy of Sciences of the United States of America. 93: 13327-32. PMID 8917590 DOI: 10.1073/Pnas.93.23.13327  0.488
1996 Matteoli M, Verderio C, Rossetto O, Iezzi N, Coco S, Schiavo G, Montecucco C. Synaptic vesicle endocytosis mediates the entry of tetanus neurotoxin into hippocampal neurons. Proceedings of the National Academy of Sciences of the United States of America. 93: 13310-5. PMID 8917587 DOI: 10.1073/Pnas.93.23.13310  0.575
1996 Montecucco C, Schiavo G. Structure and function of tetanus and botulinum neurotoxins. Quarterly Reviews of Biophysics. 28: 423-72. PMID 8771234 DOI: 10.1017/S0033583500003292  0.59
1996 Osen-Sand A, Staple JK, Naldi E, Schiavo G, Rossetto O, Petitpierre S, Malgaroli A, Montecucco C, Catsicas S. Common and distinct fusion proteins in axonal growth and transmitter release. The Journal of Comparative Neurology. 367: 222-34. PMID 8708006 DOI: 10.1002/(Sici)1096-9861(19960401)367:2<222::Aid-Cne5>3.0.Co;2-7  0.611
1996 Morante S, Furenlid L, Schiavo G, Tonello F, Zwilling R, Montecucco C. X-ray absorption spectroscopy study of zinc coordination in tetanus neurotoxin, astacin, alkaline protease and thermolysin. European Journal of Biochemistry. 235: 606-12. PMID 8654408 DOI: 10.1111/J.1432-1033.1996.00606.X  0.467
1996 Rossetto O, Gorza L, Schiavo G, Schiavo N, Scheller RH, Montecucco C. VAMP/synaptobrevin isoforms 1 and 2 are widely and differentially expressed in nonneuronal tissues. The Journal of Cell Biology. 132: 167-79. PMID 8567721 DOI: 10.1083/Jcb.132.1.167  0.527
1996 Schiavo G, Rossetto O, Tonello F, Montecucco C. Intracellular targets and metalloprotease activity of tetanus and botulism neurotoxins. Current Topics in Microbiology and Immunology. 195: 257-74. PMID 8542757 DOI: 10.1007/978-3-642-85173-5_12  0.565
1996 Deloye F, Schiavo G, Doussau F, Rossetto O, Montecucco C, Poulain B. Mode d'action moléculaire des neurotoxines botulique et tétanique MéDecine/Sciences. 12: 175. DOI: 10.4267/10608/708  0.366
1995 Schiavo G, Rossetto O, Montecucco C. Clostridial neurotoxins as tools to investigate the molecular events of neurotransmitter release. Seminars in Cell Biology. 5: 221-9. PMID 7994006 DOI: 10.1006/Scel.1994.1028  0.565
1995 Menestrina G, Schiavo G, Montecucco C. Molecular mechanisms of action of bacterial protein toxins. Molecular Aspects of Medicine. 15: 79-193. PMID 7984032 DOI: 10.1016/0098-2997(94)90043-4  0.503
1995 Kochi SK, Schiavo G, Mock M, Montecucco C. Zinc content of the Bacillus anthracis lethal factor. Fems Microbiology Letters. 124: 343-8. PMID 7851740 DOI: 10.1111/J.1574-6968.1994.Tb07306.X  0.476
1995 Washbourne P, Schiavo G, Montecucco C. Vesicle-associated membrane protein-2 (synaptobrevin-2) forms a complex with synaptophysin. The Biochemical Journal. 305: 721-4. PMID 7848269 DOI: 10.1042/Bj3050721  0.538
1995 Schiavo G, Shone CC, Bennett MK, Scheller RH, Montecucco C. Botulinum neurotoxin type C cleaves a single Lys-Ala bond within the carboxyl-terminal region of syntaxins. The Journal of Biological Chemistry. 270: 10566-70. PMID 7737992 DOI: 10.1074/Jbc.270.18.10566  0.487
1995 Schiavo G, Montecucco C. Tetanus and botulism neurotoxins: isolation and assay. Methods in Enzymology. 248: 643-52. PMID 7674951 DOI: 10.1016/0076-6879(95)48041-2  0.445
1995 Rossetto O, Deloye F, Poulain B, Pellizzari R, Schiavo G, Montecucco C. The metallo-proteinase activity of tetanus and botulism neurotoxins. Journal of Physiology, Paris. 89: 43-50. PMID 7581298 DOI: 10.1016/0928-4257(96)80550-X  0.559
1995 Nielander HB, Onofri F, Valtorta F, Schiavo G, Montecucco C, Greengard P, Benfenati F. Phosphorylation of VAMP/synaptobrevin in synaptic vesicles by endogenous protein kinases. Journal of Neurochemistry. 65: 1712-20. PMID 7561869 DOI: 10.1046/J.1471-4159.1995.65041712.X  0.521
1995 Schiavo G, Gmachl MJ, Stenbeck G, Söllner TH, Rothman JE. A possible docking and fusion particle for synaptic transmission. Nature. 378: 733-6. PMID 7501022 DOI: 10.1038/378733A0  0.508
1995 Filippis VD, Vangelista L, Schiavo G, Tonello F, Montecucco C. Structural studies on the zinc-endopeptidase light chain of tetanus neurotoxin. Febs Journal. 229: 61-69. DOI: 10.1111/J.1432-1033.1995.0061L.X  0.473
1995 Nielander HB, Onofri F, Valtorta F, Schiavo G, Montecucco C, Greengard P, Benfenati F. Phosphorylation of VAMP/synaptobrevin in synaptic vesicles Pharmacological Research. 31: 212. DOI: 10.1016/1043-6618(95)87108-X  0.491
1995 Montecucco C, Schiavo G, Rossetto O, Poulain B. The mechanism of action of tetanus and botullnum naurotoxins Toxicology Letters. 78: 8. DOI: 10.1016/0378-4274(95)94630-Y  0.463
1994 Montecucco C, Papini E, Schiavo G. Bacterial protein toxins penetrate cells via a four-step mechanism. Febs Letters. 346: 92-8. PMID 8206166 DOI: 10.1016/0014-5793(94)00449-8  0.554
1994 Kochi SK, Martin I, Schiavo G, Mock M, Cabiaux V. The effects of pH on the interaction of anthrax toxin lethal and edema factors with phospholipid vesicles. Biochemistry. 33: 2604-2609. PMID 8117722 DOI: 10.1021/Bi00175A032  0.312
1994 Rossetto O, Schiavo G, Montecucco C, Poulain B, Deloye F, Lozzi L, Shone CC. SNARE motif and neurotoxins. Nature. 372: 415-6. PMID 7984234 DOI: 10.1038/372415A0  0.496
1994 Schiavo G, Rossetto O, Benfenati F, Poulain B, Montecucco C. Tetanus and botulinum neurotoxins are zinc proteases specific for components of the neuroexocytosis apparatus. Annals of the New York Academy of Sciences. 710: 65-75. PMID 7786341 DOI: 10.1111/J.1749-6632.1994.Tb26614.X  0.556
1994 Montecucco C, Schiavo G. Mechanism of action of tetanus and botulinum neurotoxins. Molecular Microbiology. 13: 1-8. PMID 7527117 DOI: 10.1111/J.1365-2958.1994.Tb00396.X  0.514
1994 Schiavo G, Montecucco C. Response from Schiavo and Montecucco Trends in Microbiology. 2: 69. DOI: 10.1016/0966-842X(94)90533-9  0.422
1993 Poulain B, Rossetto O, Deloye F, Schiavo G, Tauc L, Montecucco C. Antibodies against rat brain vesicle-associated membrane protein (synaptobrevin) prevent inhibition of acetylcholine release by tetanus toxin or botulinum neurotoxin type B. Journal of Neurochemistry. 61: 1175-8. PMID 8395562 DOI: 10.1111/J.1471-4159.1993.Tb03640.X  0.54
1993 Patarnello T, Bargelloni L, Rossetto O, Schiavo G, Montecucco C. Neurotransmission and secretion. Nature. 364: 581-582. PMID 8350917 DOI: 10.1038/364582A0  0.456
1993 de Paiva A, Ashton AC, Foran P, Schiavo G, Montecucco C, Dolly JO. Botulinum A like type B and tetanus toxins fulfils criteria for being a zinc-dependent protease. Journal of Neurochemistry. 61: 2338-41. PMID 8245989 DOI: 10.1111/J.1471-4159.1993.Tb07482.X  0.513
1993 Schiavo G, Santucci A, Dasgupta BR, Mehta PP, Jontes J, Benfenati F, Wilson MC, Montecucco C. Botulinum neurotoxins serotypes A and E cleave SNAP-25 at distinct COOH-terminal peptide bonds. Febs Letters. 335: 99-103. PMID 8243676 DOI: 10.1016/0014-5793(93)80448-4  0.521
1993 Schiavo G, Poulain B, Benfenati F, DasGupta BR, Montecucco C. Novel targets and catalytic activities of bacterial protein toxins. Trends in Microbiology. 1: 170-4. PMID 8143134 DOI: 10.1016/0966-842X(93)90086-7  0.556
1993 Montecucco C, Schiavo G. Tetanus and botulism neurotoxins: a new group of zinc proteases. Trends in Biochemical Sciences. 18: 324-7. PMID 7901925 DOI: 10.1016/0968-0004(93)90065-U  0.516
1992 Rossetto O, Schiavo G, Polverino de Laureto P, Fabbiani S, Montecucco C. Surface topography of histidine residues of tetanus toxin probed by immobilized-metal-ion affinity chromatography. The Biochemical Journal. 9-12. PMID 1637325 DOI: 10.1042/Bj2850009  0.477
1992 Calappi E, Masserini M, Schiavo G, Montecucco C, Tettamanti G. Lipid interaction of tetanus neurotoxin. A calorimetric and fluorescence spectroscopy study. Febs Letters. 309: 107-10. PMID 1505672 DOI: 10.1016/0014-5793(92)81074-V  0.505
1992 Schiavo G, Poulain B, Rossetto O, Benfenati F, Tauc L, Montecucco C. Tetanus toxin is a zinc protein and its inhibition of neurotransmitter release and protease activity depend on zinc. The Embo Journal. 11: 3577-83. PMID 1396558 DOI: 10.1002/J.1460-2075.1992.Tb05441.X  0.547
1992 Montecucco C, Papini E, Schiavo G, Padovan E, Rossetto O. Ion channel and membrane translocation of diphtheria toxin. Fems Microbiology Immunology. 5: 101-11. PMID 1384590 DOI: 10.1111/J.1574-6968.1992.Tb05892.X  0.501
1992 Schiavo G, Benfenati F, Poulain B, Rossetto O, Polverino de Laureto P, DasGupta BR, Montecucco C. Tetanus and botulinum-B neurotoxins block neurotransmitter release by proteolytic cleavage of synaptobrevin. Nature. 359: 832-5. PMID 1331807 DOI: 10.1038/359832A0  0.485
1991 Schiavo G, Papini E, Genna G, Montecucco C. An intact interchain disulfide bond is required for the neurotoxicity of tetanus toxin. Infection and Immunity. 58: 4136-41. PMID 2254033 DOI: 10.1128/Iai.58.12.4136-4141.1990  0.529
1991 Demel R, Schiavo G, de Kruijff B, Montecucco C. Lipid interaction of diphtheria toxin and mutants. A study with phospholipid and protein monolayers. European Journal of Biochemistry. 197: 481-6. PMID 2026170 DOI: 10.1111/J.1432-1033.1991.Tb15935.X  0.476
1991 Schiavo G, Ferrari G, Rossetto O, Montecucco C. Tetanus toxin receptor. Specific cross-linking of tetanus toxin to a protein of NGF-differentiated PC 12 cells. Febs Letters. 290: 227-30. PMID 1915881 DOI: 10.1016/0014-5793(91)81266-B  0.511
1991 Schiavo G, Demel R, Montecucco C. On the role of polysialoglycosphingolipids as tetanus toxin receptors. A study with lipid monolayers. European Journal of Biochemistry. 199: 705-11. PMID 1868854 DOI: 10.1111/J.1432-1033.1991.Tb16174.X  0.502
1991 Rossetto O, Schiavo G, Ferrari G, Basso G, Montecucco C. Killing of neuroblastoma and pheochromocytoma cells in colture with tetanus-diphtheria hybrid toxins European Journal of Cancer and Clinical Oncology. 27: S84. DOI: 10.1016/0277-5379(91)91560-6  0.399
1990 Papini E, Schiavo G, Rappuoli R, Montecucco C. Histidine-21 is involved in diphtheria toxin NAD+ binding. Toxicon : Official Journal of the International Society On Toxinology. 28: 631-5. PMID 2402759 DOI: 10.1016/0041-0101(90)90251-2  0.477
1990 Dabbeni-Sala F, Schiavo G, Palatini P. Mechanism of local anesthetic effect on mitochondrial ATP synthase as deduced from photolabelling and inhibition studies with phenothiazine derivatives. Biochimica Et Biophysica Acta. 1026: 117-125. PMID 2143082 DOI: 10.1016/0005-2736(90)90341-K  0.307
1990 SCHIAVO G, PAPINI E, MONTECUCCO C. An intact interchain SS bond is required for the neurotoxicity of tetanus toxin Cell Biology International Reports. 14: 259. DOI: 10.1016/0309-1651(90)91135-Q  0.455
1989 Montecucco C, Schiavo G, Dasgupta BR. Effect of pH on the interaction of botulinum neurotoxins A, B and E with liposomes. The Biochemical Journal. 259: 47-53. PMID 2719650 DOI: 10.1042/Bj2590047  0.48
1988 Papini E, Schiavo G, Tomasi M, Colombatti M, Rappuoli R, Montecucco C. Lipid interaction of diphtheria toxin and mutants with altered fragment B. 2. Hydrophobic photolabelling and cell intoxication. European Journal of Biochemistry. 169: 637-44. PMID 3691512 DOI: 10.1111/J.1432-1033.1987.Tb13655.X  0.513
1988 Montecucco C, Schiavo G, Gao Z, Bauerlein E, Boquet P, DasGupta BR. Interaction of botulinum and tetanus toxins with the lipid bilayer surface. The Biochemical Journal. 251: 379-83. PMID 3401212 DOI: 10.1042/Bj2510379  0.509
1987 Papini E, Colonna R, Schiavo G, Cusinato F, Tomasi M, Rappuoli R, Montecucco C. Diphtheria toxin and its mutant crm 197 differ in their interaction with lipids. Febs Letters. 215: 73-8. PMID 3569541 DOI: 10.1016/0014-5793(87)80116-3  0.502
1987 Degli Esposti M, Avitabile E, Barilli M, Schiavo G, Montecucco C, Lenaz G. Comparative biochemistry of the ubiquinol-cytochrome c oxidoreductase (EC isolated from different heart mitochondria. Comparative Biochemistry and Physiology. B, Comparative Biochemistry. 85: 543-52. PMID 3024904 DOI: 10.1016/0305-0491(86)90044-1  0.468
1987 Montecucco C, Schiavo G. 1-Palmitoyl-2-(p-benzoyl)benzoyl phosphatidylcholine, a photoactive phospholipid for the labelling of membrane components. The Biochemical Journal. 237: 309-12. PMID 2948491 DOI: 10.1042/Bj2370309  0.495
1987 Montecucco C, Schiavo G, Bacci B, Bisson R. Isolation and characterization of cytochrome c oxidase from bird and fish heart mitochondria. Comparative Biochemistry and Physiology. B, Comparative Biochemistry. 87: 851-6. PMID 2822348 DOI: 10.1016/0305-0491(87)90401-9  0.455
1986 Montecucco C, Schiavo G, Brunner J, Duflot E, Boquet P, Roa M. Tetanus toxin is labeled with photoactivatable phospholipids at low pH Biochemistry. 25: 919-924. PMID 3964653 DOI: 10.1021/Bi00352A027  0.505
1986 Montecucco C, Tomasi M, Schiavo G, Rappuoli R. Hydrophobic photolabelling of pertussis toxin subunits interacting with lipids. Febs Letters. 194: 301-4. PMID 3940899 DOI: 10.1016/0014-5793(86)80105-3  0.514
1986 Montecucco C, Schiavo G, Bisson R. ATP binding to bovine heart cytochrome c oxidase. A photoaffinity labelling study. The Biochemical Journal. 234: 241-3. PMID 3010954 DOI: 10.1042/Bj2340241  0.478
1985 Montecucco C, Schiavo G, Tomasi M. pH-dependence of the phospholipid interaction of diphtheria-toxin fragments. The Biochemical Journal. 231: 123-8. PMID 4062882 DOI: 10.1042/Bj2310123  0.488
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