Robert L. Macdonald - Publications

Affiliations: 
Vanderbilt University, Nashville, TN 
Area:
GABA, epilepsy

187 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Hernandez CC, XiangWei W, Hu N, Shen D, Shen W, Lagrange AH, Zhang Y, Dai L, Ding C, Sun Z, Hu J, Zhu H, Jiang Y, Macdonald RL. Altered inhibitory synapses in de novo GABRA5 and GABRA1 mutations associated with early onset epileptic encephalopathies. Brain : a Journal of Neurology. PMID 31056671 DOI: 10.1093/brain/awz123  0.72
2019 Hernandez CC, Macdonald RL. A Structural Look at GABA Receptor Mutations Linked to Epilepsy Syndromes. Brain Research. PMID 30851244 DOI: 10.1016/j.brainres.2019.03.004  0.72
2018 Lagrange AH, Hu N, Macdonald RL. GABA beyond the synapse-defining the subtype-specific pharmacodynamics of nonsynaptic GABA receptors. The Journal of Physiology. PMID 30019335 DOI: 10.1113/JP276187  0.72
2018 Lin H, Hu N, Zhang Y, Wang Y, Macdonald RL. Whole exome sequencing reveals novel NOV and DCAF13 variants in a Chinese pedigree with familial cortical myoclonic tremor with epilepsy. Neuroscience Letters. PMID 30003937 DOI: 10.1016/j.neulet.2018.07.014  0.72
2018 Wang CH, Hernandez CC, Wu J, Zhou N, Hsu HY, Shen ML, Wang YC, Macdonald RL, Wu DC. A missense mutation A384P associated with human hyperekplexia reveals a desensitization site of glycine receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29440552 DOI: 10.1523/JNEUROSCI.0674-16.2018  0.72
2017 Hernandez CC, Zhang Y, Hu N, Shen D, Shen W, Liu X, Kong W, Jiang Y, Macdonald RL. GABA A Receptor Coupling Junction and Pore GABRB3 Mutations are Linked to Early-Onset Epileptic Encephalopathy. Scientific Reports. 7: 15903. PMID 29162865 DOI: 10.1038/s41598-017-16010-3  0.72
2017 Huang X, Zhou C, Tian M, Kang JQ, Shen W, Verdier K, Pimenta A, MacDonald RL. Overexpressing wild-type γ2 subunits rescued the seizure phenotype in Gabrg2(+/Q390X) Dravet syndrome mice. Epilepsia. PMID 28586508 DOI: 10.1111/epi.13810  1
2017 Warner TA, Liu Z, Macdonald RL, Kang JQ. Heat induced temperature dysregulation and seizures in Dravet Syndrome/GEFS+ Gabrg2(+/Q390X) mice. Epilepsy Research. 134: 1-8. PMID 28505490 DOI: 10.1016/j.eplepsyres.2017.04.020  0.6
2017 Hernandez CC, Kong W, Hu N, Zhang Y, Shen W, Jackson L, Liu X, Jiang Y, Macdonald RL. Altered Channel Conductance States and Gating of GABAA Receptors by a Pore Mutation Linked to Dravet Syndrome. Eneuro. 4. PMID 28197552 DOI: 10.1523/ENEURO.0251-16.2017  0.72
2016 Delahanty RJ, Zhang Y, Bichell TJ, Shen W, Verdier K, Macdonald RL, Xu L, Boyd K, Williams J, Kang JQ. Beyond Epilepsy and Autism: Disruption of GABRB3 Causes Ocular Hypopigmentation. Cell Reports. 17: 3115-3124. PMID 28009282 DOI: 10.1016/j.celrep.2016.11.067  0.6
2016 Hernandez CC, Klassen TL, Jackson LG, Gurba K, Hu N, Noebels JL, Macdonald RL. Correction: Deleterious Rare Variants Reveal Risk for Loss of GABAA Receptor Function in Patients with Genetic Epilepsy and in the General Population. Plos One. 11: e0167264. PMID 27870904 DOI: 10.1371/journal.pone.0167264  0.72
2016 Shen D, Hernandez CC, Shen W, Hu N, Poduri A, Shiedley B, Rotenberg A, Datta AN, Leiz S, Patzer S, Boor R, Ramsey K, Goldberg E, Helbig I, Ortiz-Gonzalez XR, ... ... Macdonald RL, et al. De novo GABRG2 mutations associated with epileptic encephalopathies. Brain : a Journal of Neurology. PMID 27864268 DOI: 10.1093/brain/aww272  0.72
2016 Ishii A, Kang JQ, Schornak CC, Hernandez CC, Shen W, Watkins JC, Macdonald RL, Hirose S. A de novo missense mutation of GABRB2 causes early myoclonic encephalopathy. Journal of Medical Genetics. PMID 27789573 DOI: 10.1136/jmedgenet-2016-104083  0.72
2016 Wang J, Shen D, Xia G, Shen W, Macdonald RL, Xu D, Kang JQ. Differential protein structural disturbances and suppression of assembly partners produced by nonsense GABRG2 epilepsy mutations: implications for disease phenotypic heterogeneity. Scientific Reports. 6: 35294. PMID 27762395 DOI: 10.1038/srep35294  0.6
2016 Hernandez CC, Klassen TL, Jackson LG, Gurba K, Hu N, Noebels JL, Macdonald RL. Deleterious Rare Variants Reveal Risk for Loss of GABAA Receptor Function in Patients with Genetic Epilepsy and in the General Population. Plos One. 11: e0162883. PMID 27622563 DOI: 10.1371/journal.pone.0162883  0.72
2016 Botzolakis EJ, Gurba KN, Lagrange AH, Feng HJ, Stanic AK, Hu N, Macdonald RL. Comparison of GABA-A Receptor αβγ and αβδ Expression Using Flow Cytometry and Electrophysiology: Evidence for Alternate Subunit Stoichiometries and Arrangements. The Journal of Biological Chemistry. PMID 27493204 DOI: 10.1074/jbc.M115.698860  1
2016 Kang JQ, Macdonald RL. Molecular Pathogenic Basis for GABRG2 Mutations Associated With a Spectrum of Epilepsy Syndromes, From Generalized Absence Epilepsy to Dravet Syndrome. Jama Neurology. PMID 27367160 DOI: 10.1001/jamaneurol.2016.0449  0.6
2016 Warner TA, Shen W, Huang X, Liu Z, Macdonald RL, Kang JQ. DIfferential molecular and behavioral alterations in mouse models of GABRG2 haploinsufficiency versus dominant negative mutations associated with human epilepsy. Human Molecular Genetics. PMID 27340224 DOI: 10.1093/hmg/ddw168  0.72
2016 Janve VS, Hernandez CC, Verdier KM, Hu N, Macdonald RL. Reply. Annals of Neurology. PMID 27270493 DOI: 10.1002/ana.24701  0.72
2016 Janve VS, Hernandez CC, Verdier KM, Hu N, Macdonald RL. Epileptic encephalopathy de novo GABRB mutations impair GABAA receptor function. Annals of Neurology. PMID 26950270 DOI: 10.1002/ana.24631  0.72
2015 Ayling OG, Ibrahim GM, Macdonald RL. Response. J Neurosurg. 123: 619-20. PMID 26668966  0.32
2015 Ayling OG, Ibrahim GM, Macdonald RL. Response. Journal of Neurosurgery. 123: 619-20. PMID 26561672  0.32
2015 Kang JQ, Shen W, Zhou C, Xu D, Macdonald RL. The human epilepsy mutation GABRG2(Q390X) causes chronic subunit accumulation and neurodegeneration. Nature Neuroscience. 18: 988-96. PMID 26005849 DOI: 10.1038/nn.4024  1
2015 Macdonald RL, Chen HYH, Bartels SF, Palik BJ, Prepas EE. Compositional stability of boreal understorey vegetation after overstorey harvesting across a riparian ecotone Journal of Vegetation Science. 26: 733-741. DOI: 10.1111/jvs.12272  0.56
2014 Todd E, Gurba KN, Botzolakis EJ, Stanic AK, Macdonald RL. GABAA receptor biogenesis is impaired by the γ2 subunit febrile seizure-associated mutation, GABRG2(R177G). Neurobiology of Disease. 69: 215-24. PMID 24874541 DOI: 10.1016/j.nbd.2014.05.013  1
2014 Huang X, Hernandez CC, Hu N, Macdonald RL. Three epilepsy-associated GABRG2 missense mutations at the γ+/β- interface disrupt GABAA receptor assembly and trafficking by similar mechanisms but to different extents. Neurobiology of Disease. 68: 167-79. PMID 24798517 DOI: 10.1016/j.nbd.2014.04.015  1
2014 Johnston AJ, Kang JQ, Shen W, Pickrell WO, Cushion TD, Davies JS, Baer K, Mullins JG, Hammond CL, Chung SK, Thomas RH, White C, Smith PE, Macdonald RL, Rees MI. A novel GABRG2 mutation, p.R136*, in a family with GEFS+ and extended phenotypes. Neurobiology of Disease. 64: 131-41. PMID 24407264 DOI: 10.1016/j.nbd.2013.12.013  1
2014 Lo WY, Lagrange AH, Hernandez CC, Gurba KN, Macdonald RL. Co-expression of γ2 subunits hinders processing of N-linked glycans attached to the N104 glycosylation sites of GABAA receptor β2 subunits. Neurochemical Research. 39: 1088-103. PMID 24213971 DOI: 10.1007/s11064-013-1187-9  1
2014 MacDonald RL, Chen HYH, Palik BP, Prepas EE. Influence of harvesting on understory vegetation along a boreal riparian-upland gradient Forest Ecology and Management. 312: 138-147. DOI: 10.1016/j.foreco.2013.10.011  0.56
2014 Macdonald RL, Gallagher MJ. Properties and Regulation of GABAA and Glycine Receptor Channels Reference Module in Biomedical Research. DOI: 10.1016/B978-0-12-801238-3.00031-3  1
2014 Macdonald RL, Gallagher MJ. The Genetic Epilepsies Rosenberg's Molecular and Genetic Basis of Neurological and Psychiatric Disease: Fifth Edition. 973-998. DOI: 10.1016/B978-0-12-410529-4.00084-X  1
2013 Kang JQ, Shen W, Macdonald RL. Trafficking-deficient mutant GABRG2 subunit amount may modify epilepsy phenotype. Annals of Neurology. 74: 547-59. PMID 23720301 DOI: 10.1002/ana.23947  1
2013 Tian M, Mei D, Freri E, Hernandez CC, Granata T, Shen W, Macdonald RL, Guerrini R. Impaired surface αβγ GABA(A) receptor expression in familial epilepsy due to a GABRG2 frameshift mutation. Neurobiology of Disease. 50: 135-41. PMID 23069679 DOI: 10.1016/j.nbd.2012.10.008  1
2013 Zomorodi A, Herndon JE, Sampson JH. Subarachnoid hemorrhage trials. Journal of Neurosurgery. 118: 1-2; discussion 2. PMID 23039153 DOI: 10.3171/2012.5.JNS12730  0.32
2012 Macdonald RL, Kang JQ. mRNA surveillance and endoplasmic reticulum quality control processes alter biogenesis of mutant GABAA receptor subunits associated with genetic epilepsies. Epilepsia. 53: 59-70. PMID 23216579 DOI: 10.1111/epi.12035  1
2012 Porter RJ, Dhir A, Macdonald RL, Rogawski MA. Mechanisms of action of antiseizure drugs. Handbook of Clinical Neurology. 108: 663-81. PMID 22939059 DOI: 10.1016/B978-0-444-52899-5.00021-6  1
2012 Russin JJ, Mack WJ, Carey JN, Minneti M, Giannotta SL. Simulation of a high-flow extracranial-intracranial bypass using a radial artery graft in a novel fresh tissue model. Neurosurgery. 71: ons315-19; discussio. PMID 22791034 DOI: 10.1227/NEU.0b013e318266e7c6  0.32
2012 Huang X, Tian M, Hernandez CC, Hu N, Macdonald RL. The GABRG2 nonsense mutation, Q40X, associated with Dravet syndrome activated NMD and generated a truncated subunit that was partially rescued by aminoglycoside-induced stop codon read-through. Neurobiology of Disease. 48: 115-23. PMID 22750526 DOI: 10.1016/j.nbd.2012.06.013  1
2012 Wu X, Wu Z, Ning G, Guo Y, Ali R, Macdonald RL, De Blas AL, Luscher B, Chen G. γ-Aminobutyric acid type A (GABAA) receptor α subunits play a direct role in synaptic versus extrasynaptic targeting. The Journal of Biological Chemistry. 287: 27417-30. PMID 22711532 DOI: 10.1074/jbc.M112.360461  1
2012 Kapadia AN, Naik NP, MacDonald RL, Schweizer TA. Cognitive and mood profile of sturge-weber syndrome affecting the thalamus Canadian Journal of Neurological Sciences. 39: 402-404. PMID 22666901  0.32
2012 Tian M, Macdonald RL. The intronic GABRG2 mutation, IVS6+2T->G, associated with childhood absence epilepsy altered subunit mRNA intron splicing, activated nonsense-mediated decay, and produced a stable truncated γ2 subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5937-52. PMID 22539854 DOI: 10.1523/JNEUROSCI.5332-11.2012  1
2012 Gurba KN, Hernandez CC, Hu N, Macdonald RL. GABRB3 mutation, G32R, associated with childhood absence epilepsy alters α1β3γ2L γ-aminobutyric acid type A (GABAA) receptor expression and channel gating. The Journal of Biological Chemistry. 287: 12083-97. PMID 22303015 DOI: 10.1074/jbc.M111.332528  1
2012 Ibrahim GM, Macdonald RL. Letter to the Editor regarding: Method of Aneurysm Treatment Does Not Affect Clot Clearance After Aneurysmal Subarachnoid Hemorrhage. Neurosurgery. PMID 22262144 DOI: 10.1227/NEU.0b013e31824af48f  0.32
2012 MacDonald RL, Burke JM, Chen HYH, Prepas EE. Relationship between aboveground biomass and percent cover of ground vegetation in Canadian Boreal Plain riparian forests Forest Science. 58: 47-53. DOI: 10.5849/forsci.10-129  0.56
2012 MacDonald RL. Reversal of transcranial Doppler vasospasm with sildenafil Surgical Neurology International. 3. DOI: 10.4103/2152-7806.92164  0.32
2012 MacDonald RL. Comments Neurosurgery. 71: 677. DOI: 10.1227/NEU.0b013e318261749b  0.32
2011 Wong GK, Poon WS. Clazosentan for patients with subarachnoid haemorrhage: lessons learned. The Lancet. Neurology. 10: 871; author reply 87. PMID 21939894 DOI: 10.1016/S1474-4422(11)70189-2  0.32
2011 Hernandez CC, Gurba KN, Hu N, Macdonald RL. The GABRA6 mutation, R46W, associated with childhood absence epilepsy, alters 6β22 and 6β2 GABA(A) receptor channel gating and expression. The Journal of Physiology. 589: 5857-78. PMID 21930603 DOI: 10.1113/jphysiol.2011.218883  1
2011 Botzolakis EJ, Zhao J, Gurba KN, Macdonald RL, Hedera P. The effect of HSP-causing mutations in SPG3A and NIPA1 on the assembly, trafficking, and interaction between atlastin-1 and NIPA1. Molecular and Cellular Neurosciences. 46: 122-35. PMID 20816793 DOI: 10.1016/j.mcn.2010.08.012  1
2011 Delahanty RJ, Kang JQ, Brune CW, Kistner EO, Courchesne E, Cox NJ, Cook EH, Macdonald RL, Sutcliffe JS. Maternal transmission of a rare GABRB3 signal peptide variant is associated with autism. Molecular Psychiatry. 16: 86-96. PMID 19935738 DOI: 10.1038/mp.2009.118  1
2011 MacDonald RL. Cognitive function after subarachnoid hemorrhage: Novel results of testing in the acute setting World Neurosurgery. 75: 596-597. DOI: 10.1016/j.wneu.2010.12.024  0.32
2010 Kang JQ, Shen W, Lee M, Gallagher MJ, Macdonald RL. Slow degradation and aggregation in vitro of mutant GABAA receptor gamma2(Q351X) subunits associated with epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13895-905. PMID 20943930 DOI: 10.1523/JNEUROSCI.2320-10.2010  1
2010 Feng HJ, Kao C, Gallagher MJ, Jansen ED, Mahadevan-Jansen A, Konrad PE, Macdonald RL. Alteration of GABAergic neurotransmission by pulsed infrared laser stimulation. Journal of Neuroscience Methods. 192: 110-4. PMID 20654645 DOI: 10.1016/j.jneumeth.2010.07.014  1
2010 Lo WY, Lagrange AH, Hernandez CC, Harrison R, Dell A, Haslam SM, Sheehan JH, Macdonald RL. Glycosylation of {beta}2 subunits regulates GABAA receptor biogenesis and channel gating. The Journal of Biological Chemistry. 285: 31348-61. PMID 20639197 DOI: 10.1074/jbc.M110.151449  1
2010 Al-Khindi T, Macdonald RL, Schweizer TA. Cognitive and functional outcome after aneurysmal subarachnoid hemorrhage. Stroke; a Journal of Cerebral Circulation. 41: e519-36. PMID 20595669 DOI: 10.1161/STROKEAHA.110.581975  0.01
2010 Ding L, Feng HJ, Macdonald RL, Botzolakis EJ, Hu N, Gallagher MJ. GABA(A) receptor alpha1 subunit mutation A322D associated with autosomal dominant juvenile myoclonic epilepsy reduces the expression and alters the composition of wild type GABA(A) receptors. The Journal of Biological Chemistry. 285: 26390-405. PMID 20551311 DOI: 10.1074/jbc.M110.142299  1
2010 Feng HJ, Macdonald RL. Barbiturates require the N terminus and first transmembrane domain of the delta subunit for enhancement of alpha1beta3delta GABAA receptor currents. The Journal of Biological Chemistry. 285: 23614-21. PMID 20525684 DOI: 10.1074/jbc.M110.122564  1
2010 Macdonald RL, Kang JQ, Gallagher MJ. Mutations in GABAA receptor subunits associated with genetic epilepsies. The Journal of Physiology. 588: 1861-9. PMID 20308251 DOI: 10.1113/jphysiol.2010.186999  1
2010 Tang X, Hernandez CC, Macdonald RL. Modulation of spontaneous and GABA-evoked tonic alpha4beta3delta and alpha4beta3gamma2L GABAA receptor currents by protein kinase A. Journal of Neurophysiology. 103: 1007-19. PMID 19939957 DOI: 10.1152/jn.00801.2009  1
2010 MacDonald RL, Kang JQ, Gallagher MJ. Genetic epilepsies and GABAA receptor mutations Epilepsia. 51: 64. DOI: 10.1111/j.1528-1167.2010.02850.x  1
2010 Macdonald RL, Botzolakis EJ. GABAA receptor channels Physiology and Pathology of Chloride Transporters and Channels in the Nervous System. 257-282. DOI: 10.1016/B978-0-12-374373-2.00014-5  1
2009 Belelli D, Harrison NL, Maguire J, Macdonald RL, Walker MC, Cope DW. Extrasynaptic GABAA receptors: form, pharmacology, and function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12757-63. PMID 19828786 DOI: 10.1523/JNEUROSCI.3340-09.2009  1
2009 Kang JQ, Macdonald RL. Making sense of nonsense GABA(A) receptor mutations associated with genetic epilepsies. Trends in Molecular Medicine. 15: 430-8. PMID 19717338 DOI: 10.1016/j.molmed.2009.07.003  1
2009 Bianchi MT, Botzolakis EJ, Lagrange AH, Macdonald RL. Benzodiazepine modulation of GABA(A) receptor opening frequency depends on activation context: a patch clamp and simulation study. Epilepsy Research. 85: 212-20. PMID 19447010 DOI: 10.1016/j.eplepsyres.2009.03.007  1
2009 Lewis AS, Schwartz E, Chan CS, Noam Y, Shin M, Wadman WJ, Surmeier DJ, Baram TZ, Macdonald RL, Chetkovich DM. Alternatively spliced isoforms of TRIP8b differentially control h channel trafficking and function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6250-65. PMID 19439603 DOI: 10.1523/JNEUROSCI.0856-09.2009  1
2009 Macdonald RL, Kang JQ. Molecular pathology of genetic epilepsies associated with GABAA receptor subunit mutations. Epilepsy Currents / American Epilepsy Society. 9: 18-23. PMID 19396344 DOI: 10.1111/j.1535-7511.2008.01278.x  0.6
2009 Kang JQ, Shen W, Macdonald RL. The GABRG2 mutation, Q351X, associated with generalized epilepsy with febrile seizures plus, has both loss of function and dominant-negative suppression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2845-56. PMID 19261880 DOI: 10.1523/JNEUROSCI.4772-08.2009  1
2009 Kang JQ, Shen W, Macdonald RL. Two molecular pathways (NMD and ERAD) contribute to a genetic epilepsy associated with the GABA(A) receptor GABRA1 PTC mutation, 975delC, S326fs328X. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2833-44. PMID 19261879 DOI: 10.1523/JNEUROSCI.4512-08.2009  1
2009 Botzolakis EJ, Maheshwari A, Feng HJ, Lagrange AH, Shaver JH, Kassebaum NJ, Venkataraman R, Baudenbacher F, Macdonald RL. Achieving synaptically relevant pulses of neurotransmitter using PDMS microfluidics. Journal of Neuroscience Methods. 177: 294-302. PMID 19013195 DOI: 10.1016/j.jneumeth.2008.10.014  1
2009 Feng HJ, Botzolakis EJ, Macdonald RL. Context-dependent modulation of alphabetagamma and alphabetadelta GABA A receptors by penicillin: implications for phasic and tonic inhibition. Neuropharmacology. 56: 161-73. PMID 18775733 DOI: 10.1016/j.neuropharm.2008.08.010  1
2008 Zhao J, Matthies DS, Botzolakis EJ, Macdonald RL, Blakely RD, Hedera P. Hereditary spastic paraplegia-associated mutations in the NIPA1 gene and its Caenorhabditis elegans homolog trigger neural degeneration in vitro and in vivo through a gain-of-function mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13938-51. PMID 19091982 DOI: 10.1523/JNEUROSCI.4668-08.2008  1
2008 Lo WY, Botzolakis EJ, Tang X, Macdonald RL. A conserved Cys-loop receptor aspartate residue in the M3-M4 cytoplasmic loop is required for GABAA receptor assembly. The Journal of Biological Chemistry. 283: 29740-52. PMID 18723504 DOI: 10.1074/jbc.M802856200  1
2008 Rula EY, Lagrange AH, Jacobs MM, Hu N, Macdonald RL, Emeson RB. Developmental modulation of GABA(A) receptor function by RNA editing. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6196-201. PMID 18550761 DOI: 10.1523/JNEUROSCI.0443-08.2008  1
2008 Tanaka M, Olsen RW, Medina MT, Schwartz E, Alonso ME, Duron RM, Castro-Ortega R, Martinez-Juarez IE, Pascual-Castroviejo I, Machado-Salas J, Silva R, Bailey JN, Bai D, Ochoa A, Jara-Prado A, ... ... Macdonald RL, et al. Hyperglycosylation and reduced GABA currents of mutated GABRB3 polypeptide in remitting childhood absence epilepsy. American Journal of Human Genetics. 82: 1249-61. PMID 18514161 DOI: 10.1016/j.ajhg.2008.04.020  1
2008 Feng HJ, Mathews GC, Kao C, Macdonald RL. Alterations of GABA A-receptor function and allosteric modulation during development of status epilepticus. Journal of Neurophysiology. 99: 1285-93. PMID 18216225 DOI: 10.1152/jn.01180.2007  1
2007 Bianchi MT, Botzolakis EJ, Haas KF, Fisher JL, Macdonald RL. Microscopic kinetic determinants of macroscopic currents: insights from coupling and uncoupling of GABAA receptor desensitization and deactivation. The Journal of Physiology. 584: 769-87. PMID 17884921 DOI: 10.1113/jphysiol.2007.142364  1
2007 Gallagher MJ, Ding L, Maheshwari A, Macdonald RL. The GABAA receptor alpha1 subunit epilepsy mutation A322D inhibits transmembrane helix formation and causes proteasomal degradation. Proceedings of the National Academy of Sciences of the United States of America. 104: 12999-3004. PMID 17670950 DOI: 10.1073/pnas.0700163104  1
2007 Macdonald RL, Pluta RM, Zhang JH. Cerebral vasospasm after subarachnoid hemorrhage: the emerging revolution. Nature Clinical Practice. Neurology. 3: 256-63. PMID 17479073 DOI: 10.1038/ncpneuro0490  0.6
2007 Hansen-Schwartz J, Vajkoczy P, Macdonald RL, Pluta RM, Zhang JH. Cerebral vasospasm: looking beyond vasoconstriction. Trends in Pharmacological Sciences. 28: 252-6. PMID 17466386 DOI: 10.1016/j.tips.2007.04.002  0.6
2007 Lagrange AH, Botzolakis EJ, Macdonald RL. Enhanced macroscopic desensitization shapes the response of alpha4 subtype-containing GABAA receptors to synaptic and extrasynaptic GABA. The Journal of Physiology. 578: 655-76. PMID 17124266 DOI: 10.1113/jphysiol.2006.122135  1
2006 Macdonald RL, Kang JQ, Gallagher MJ, Feng HJ. GABA(A) receptor mutations associated with generalized epilepsies. Advances in Pharmacology (San Diego, Calif.). 54: 147-69. PMID 17175814  0.76
2006 Audenaert D, Schwartz E, Claeys KG, Claes L, Deprez L, Suls A, Van Dyck T, Lagae L, Van Broeckhoven C, Macdonald RL, De Jonghe P. A novel GABRG2 mutation associated with febrile seizures. Neurology. 67: 687-90. PMID 16924025 DOI: 10.1212/01.wnl.0000230145.73496.a2  1
2006 Kang JQ, Shen W, Macdonald RL. Why does fever trigger febrile seizures? GABAA receptor gamma2 subunit mutations associated with idiopathic generalized epilepsies have temperature-dependent trafficking deficiencies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2590-7. PMID 16510738 DOI: 10.1523/JNEUROSCI.4243-05.2006  1
2006 Feng HJ, Kang JQ, Song L, Dibbens L, Mulley J, Macdonald RL. Delta subunit susceptibility variants E177A and R220H associated with complex epilepsy alter channel gating and surface expression of alpha4beta2delta GABAA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1499-506. PMID 16452673 DOI: 10.1523/JNEUROSCI.2913-05.2006  1
2006 Macdonald RL, Kang JQ, Gallagher MJ, Feng HJ. GABAA Receptor Mutations Associated with Generalized Epilepsies1 Advances in Pharmacology. 54: 147-169. DOI: 10.1016/S1054-3589(06)54007-4  1
2005 Jones-Davis DM, Song L, Gallagher MJ, Macdonald RL. Structural determinants of benzodiazepine allosteric regulation of GABA(A) receptor currents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8056-65. PMID 16135763 DOI: 10.1523/JNEUROSCI.0348-05.2005  1
2005 Gallagher MJ, Shen W, Song L, Macdonald RL. Endoplasmic reticulum retention and associated degradation of a GABAA receptor epilepsy mutation that inserts an aspartate in the M3 transmembrane segment of the alpha1 subunit. The Journal of Biological Chemistry. 280: 37995-8004. PMID 16123039 DOI: 10.1074/jbc.M508305200  1
2004 Karadsheh MS, Shah MS, Tang X, Macdonald RL, Stitzel JA. Functional characterization of mouse alpha4beta2 nicotinic acetylcholine receptors stably expressed in HEK293T cells. Journal of Neurochemistry. 91: 1138-50. PMID 15569257 DOI: 10.1111/j.1471-4159.2004.02801.x  1
2004 Kang JQ, Kang J, Macdonald RL. The GABAA receptor gamma2 subunit R43Q mutation linked to childhood absence epilepsy and febrile seizures causes retention of alpha1beta2gamma2S receptors in the endoplasmic reticulum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8672-7. PMID 15470132 DOI: 10.1523/JNEUROSCI.2717-04.2004  1
2004 Macdonald RL, Gallagher MJ, Feng HJ, Kang J. GABA(A) receptor epilepsy mutations. Biochemical Pharmacology. 68: 1497-506. PMID 15451392 DOI: 10.1016/j.bcp.2004.07.029  1
2004 Feng HJ, Macdonald RL. Multiple actions of propofol on alphabetagamma and alphabetadelta GABAA receptors. Molecular Pharmacology. 66: 1517-24. PMID 15331770 DOI: 10.1124/mol.104.003426  1
2004 Feng HJ, Bianchi MT, Macdonald RL. Pentobarbital differentially modulates alpha1beta3delta and alpha1beta3gamma2L GABAA receptor currents. Molecular Pharmacology. 66: 988-1003. PMID 15247320 DOI: 10.1124/mol.104.002543  1
2004 Gallagher MJ, Song L, Arain F, Macdonald RL. The juvenile myoclonic epilepsy GABA(A) receptor alpha1 subunit mutation A322D produces asymmetrical, subunit position-dependent reduction of heterozygous receptor currents and alpha1 subunit protein expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5570-8. PMID 15201329 DOI: 10.1523/JNEUROSCI.1301-04.2004  1
2004 Feng HJ, Macdonald RL. Proton modulation of alpha 1 beta 3 delta GABAA receptor channel gating and desensitization. Journal of Neurophysiology. 92: 1577-85. PMID 15152020 DOI: 10.1152/jn.00285.2004  1
2004 Dibbens LM, Feng HJ, Richards MC, Harkin LA, Hodgson BL, Scott D, Jenkins M, Petrou S, Sutherland GR, Scheffer IE, Berkovic SF, Macdonald RL, Mulley JC. GABRD encoding a protein for extra- or peri-synaptic GABAA receptors is a susceptibility locus for generalized epilepsies. Human Molecular Genetics. 13: 1315-9. PMID 15115768 DOI: 10.1093/hmg/ddh146  1
2004 Najm I, Ying Z, Babb T, Crino PB, Macdonald R, Mathern GW, Spreafico R. Mechanisms of epileptogenicity in cortical dysplasias. Neurology. 62: S9-13. PMID 15037672  1
2003 Hinkle DJ, Macdonald RL. Beta subunit phosphorylation selectively increases fast desensitization and prolongs deactivation of alpha1beta1gamma2L and alpha1beta3gamma2L GABA(A) receptor currents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 11698-710. PMID 14684872  1
2003 Bianchi MT, Macdonald RL. Neurosteroids shift partial agonist activation of GABA(A) receptor channels from low- to high-efficacy gating patterns. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10934-43. PMID 14645489  1
2003 Macdonald RL, Bianchi MT, Bianch MT, Feng H. Mutations linked to generalized epilepsy in humans reduce GABA(A) receptor current. Experimental Neurology. 184: S58-67. PMID 14597328 DOI: 10.1016/j.expneurol.2003.08.011  1
2003 Kim H, Macdonald RL. An N-terminal histidine is the primary determinant of alpha subunit-dependent Cu2+ sensitivity of alphabeta3gamma2L GABA(A) receptors. Molecular Pharmacology. 64: 1145-52. PMID 14573764 DOI: 10.1124/mol.64.5.1145  1
2003 Hinkle DJ, Bianchi MT, Macdonald RL. Modifications of a commercial perfusion system for use in ultrafast solution exchange during patch clamp recording. Biotechniques. 35: 472-4, 476. PMID 14513550  1
2003 Kim H, Flanagin BA, Qin C, Macdonald RL, Stitzel JA. The mouse Chrna4 A529T polymorphism alters the ratio of high to low affinity alpha 4 beta 2 nAChRs. Neuropharmacology. 45: 345-54. PMID 12871652 DOI: 10.1016/S0028-3908(03)00167-9  1
2003 Jones-Davis DM, Macdonald RL. GABA(A) receptor function and pharmacology in epilepsy and status epilepticus. Current Opinion in Pharmacology. 3: 12-8. PMID 12550736 DOI: 10.1016/S1471-4892(02)00015-2  1
2002 Chen C, Bharucha V, Chen Y, Westenbroek RE, Brown A, Malhotra JD, Jones D, Avery C, Gillespie PJ, Kazen-Gillespie KA, Kazarinova-Noyes K, Shrager P, Saunders TL, Macdonald RL, Ransom BR, et al. Reduced sodium channel density, altered voltage dependence of inactivation, and increased susceptibility to seizures in mice lacking sodium channel beta 2-subunits. Proceedings of the National Academy of Sciences of the United States of America. 99: 17072-7. PMID 12481039 DOI: 10.1073/pnas.212638099  1
2002 Bianchi MT, Haas KF, Macdonald RL. Alpha1 and alpha6 subunits specify distinct desensitization, deactivation and neurosteroid modulation of GABA(A) receptors containing the delta subunit. Neuropharmacology. 43: 492-502. PMID 12367596 DOI: 10.1016/S0028-3908(02)00163-6  1
2002 Bianchi MT, Macdonald RL. Slow phases of GABA(A) receptor desensitization: structural determinants and possible relevance for synaptic function. The Journal of Physiology. 544: 3-18. PMID 12356876 DOI: 10.1113/jphysiol.2002.020255  1
2002 Jones DM, Esmaeil N, Maren S, Macdonald RL. Characterization of pharmacoresistance to benzodiazepines in the rat Li-pilocarpine model of status epilepticus. Epilepsy Research. 50: 301-12. PMID 12200221 DOI: 10.1016/S0920-1211(02)00085-2  1
2002 Buhr A, Bianchi MT, Baur R, Courtet P, Pignay V, Boulenger JP, Gallati S, Hinkle DJ, Macdonald RL, Sigel E. Functional characterization of the new human GABA(A) receptor mutation beta3(R192H). Human Genetics. 111: 154-60. PMID 12189488 DOI: 10.1007/s00439-002-0766-7  1
2002 Bianchi MT, Song L, Zhang H, Macdonald RL. Two different mechanisms of disinhibition produced by GABAA receptor mutations linked to epilepsy in humans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5321-7. PMID 12097483  1
2002 Greenfield LJ, Zaman SH, Sutherland ML, Lummis SC, Niemeyer MI, Barnard EA, Macdonald RL. Mutation of the GABAA receptor M1 transmembrane proline increases GABA affinity and reduces barbiturate enhancement. Neuropharmacology. 42: 502-21. PMID 11955521 DOI: 10.1016/S0028-3908(01)00196-4  1
2002 Wohlfarth KM, Bianchi MT, Macdonald RL. Enhanced neurosteroid potentiation of ternary GABA(A) receptors containing the delta subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 1541-9. PMID 11880484  1
2001 Bianchi MT, Macdonald RL. Agonist Trapping by GABAA Receptor Channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9083-91. PMID 11717341  1
2001 Bianchi MT, Macdonald RL. Mutation of the 9' leucine in the GABA(A) receptor gamma2L subunit produces an apparent decrease in desensitization by stabilizing open states without altering desensitized states. Neuropharmacology. 41: 737-44. PMID 11640928 DOI: 10.1016/S0028-3908(01)00132-0  1
2001 Nagaya N, Macdonald RL. Two gamma2L subunit domains confer low Zn2+ sensitivity to ternary GABA(A) receptors. The Journal of Physiology. 532: 17-30. PMID 11283222 DOI: 10.1111/j.1469-7793.2001.0017g.x  1
2001 Kelly KM, Kume A, Albin RL, Macdonald RL. Autoradiography of L-type and N-type calcium channels in aged rat hippocampus, entorhinal cortex, and neocortex. Neurobiology of Aging. 22: 17-23. PMID 11164272 DOI: 10.1016/S0197-4580(00)00178-0  1
2001 Bianchi MT, Haas KF, Macdonald RL. Structural determinants of fast desensitization and desensitization-deactivation coupling in GABAa receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1127-36. PMID 11160383  1
2000 Neelands TR, King AP, Macdonald RL. Functional expression of L-, N-, P/Q-, and R-type calcium channels in the human NT2-N cell line. Journal of Neurophysiology. 84: 2933-44. PMID 11110822  1
2000 Fisher JL, Hinkle DJ, Macdonald RL. Loreclezole inhibition of recombinant alpha1beta1gamma2L GABA(A) receptor single channel currents. Neuropharmacology. 39: 235-45. PMID 10670419 DOI: 10.1016/S0028-3908(99)00108-2  1
1999 Burgard EC, Haas KF, Macdonald RL. Channel properties determine the transient activation kinetics of recombinant GABA(A) receptors. Brain Research. Molecular Brain Research. 73: 28-36. PMID 10581395 DOI: 10.1016/S0169-328X(99)00230-2  1
1999 MacDonald RL, Kapur J. Pharmacological properties of recombinant and hippocampal dentate granule cell GABAA receptors. Advances in Neurology. 79: 979-90. PMID 10514880  1
1999 Neelands TR, Macdonald RL. Incorporation of the π subunit into functional γ-aminobutyric acid(A) receptors Molecular Pharmacology. 56: 598-610. PMID 10462548  1
1999 Neelands TR, Zhang J, Macdonald RL. GABA(A) receptors expressed in undifferentiated human teratocarcinoma NT2 cells differ from those expressed by differentiated NT2-N cells Journal of Neuroscience. 19: 7057-7065. PMID 10436060  1
1999 Macdonald RL, Kapur J. Acute cellular alterations in the hippocampus after status epilepticus. Epilepsia. 40: S9-20; discussion S2. PMID 10421557  1
1999 Kapur J, Haas KF, Macdonald RL. Physiological properties of GABAA receptors from acutely dissociated rat dentate granule cells. Journal of Neurophysiology. 81: 2464-71. PMID 10322081  1
1999 Tietz EI, Kapur J, Macdonald RL. Functional GABAA receptor heterogeneity of acutely dissociated hippocampal CA1 pyramidal cells. Journal of Neurophysiology. 81: 1575-86. PMID 10200193  1
1999 King AP, Hall KE, Macdonald RL. kappa- and mu-Opioid inhibition of N-type calcium currents is attenuated by 4beta-phorbol 12-myristate 13-acetate and protein kinase C in rat dorsal root ganglion neurons. The Journal of Pharmacology and Experimental Therapeutics. 289: 312-20. PMID 10087019  1
1999 Kapur J, Macdonald RL. Postnatal development of hippocampal dentate granule cell gamma-aminobutyric acidA receptor pharmacological properties. Molecular Pharmacology. 55: 444-52. PMID 10051527  1
1999 Lowenstein DH, Bleck T, Macdonald RL. It's time to revise the definition of status epilepticus. Epilepsia. 40: 120-2. PMID 9924914 DOI: 10.1111/j.1528-1157.1999.tb02000.x  1
1999 Neelands TR, Fisher JL, Bianchi M, Macdonald RL. Spontaneous and gamma-aminobutyric acid (GABA)-activated GABA(A) receptor channels formed by epsilon subunit-containing isoforms. Molecular Pharmacology. 55: 168-78. PMID 9882711  1
1999 Haas KF, Macdonald RL. GABAA receptor subunit gamma2 and delta subtypes confer unique kinetic properties on recombinant GABAA receptor currents in mouse fibroblasts. The Journal of Physiology. 514: 27-45. PMID 9831714  1
1999 Bleck TP, Jensen FE, Mizrahi EM, Macdonald RL. Panel discussion: Discussion and questions from the audience Epilepsia. 40: S64-S66. DOI: 10.1111/j.1528-1157.1999.tb00881.x  1
1999 Coulter DA, Sloviter RS, Macdonald RL. Panel discussion: Discussion and questions from the audience Epilepsia. 40: S40-S41. DOI: 10.1111/j.1528-1157.1999.tb00877.x  1
1999 Haas KF, Macdonald RL. GABA(A) receptor subunit γ2 and δ subtypes confer unique kinetic properties on recombinant GABA(A) receptor currents in mouse fibroblasts Journal of Physiology. 514: 27-45. DOI: 10.1111/j.1469-7793.1999.027af.x  1
1999 Macdonald RL. Introduction and symposium overview Epilepsia. 40: S1-S2.  1
1999 Lowenstein DH, Macdonald RL. Panel discussion: Discussion and questions from the audience Epilepsia. 40: S21-S22.  1
1998 Fisher JL, Macdonald RL. The role of an alpha subtype M2-M3 His in regulating inhibition of GABAA receptor current by zinc and other divalent cations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2944-53. PMID 9526011  1
1997 Macdonald RL, Weir B, Zhang J, Marton LS, Sajdak M, Johns LM. Adenosine triphosphate and hemoglobin in vasospastic monkeys. Neurosurgical Focus. 3: e3. PMID 15104409  0.88
1997 Fisher JL, Macdonald RL. Functional properties of recombinant GABA(A) receptors composed of single or multiple beta subunit subtypes. Neuropharmacology. 36: 1601-10. PMID 9517431 DOI: 10.1016/S0028-3908(97)00133-0  1
1997 Fisher JL, Macdonald RL. Single channel properties of recombinant GABAA receptors containing gamma 2 or delta subtypes expressed with alpha 1 and beta 3 subtypes in mouse L929 cells. The Journal of Physiology. 505: 283-97. PMID 9423172 DOI: 10.1111/j.1469-7793.1997.283bb.x  1
1997 Fisher JL, Zhang J, Macdonald RL. The role of alpha1 and alpha6 subtype amino-terminal domains in allosteric regulation of gamma-aminobutyric acida receptors. Molecular Pharmacology. 52: 714-24. PMID 9380035  1
1997 Kapur J, Macdonald RL. Rapid seizure-induced reduction of benzodiazepine and Zn2+ sensitivity of hippocampal dentate granule cell GABAA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 7532-40. PMID 9295398  1
1997 Wiley JW, Moises HC, Gross RA, MacDonald RL. Dynorphin A-mediated reduction in multiple calcium currents involves a G(o) alpha-subtype G protein in rat primary afferent neurons. Journal of Neurophysiology. 77: 1338-48. PMID 9084601  1
1996 Kapur J, Macdonald RL. Cyclic AMP-dependent protein kinase enhances hippocampal dentate granule cell GABAA receptor currents. Journal of Neurophysiology. 76: 2626-34. PMID 8899633  1
1996 Kapur J, Macdonald RL. Pharmacological properties of gamma-aminobutyric acidA receptors from acutely dissociated rat dentate granule cells. Molecular Pharmacology. 50: 458-66. PMID 8794882  1
1993 Wiley JW, Gross RA, MacDonald RL. Agonists for neuropeptide Y receptor subtypes NPY-1 and NPY-2 have opposite actions on rat nodose neuron calcium currents. Journal of Neurophysiology. 70: 324-30. PMID 8395583  1
1992 Wiley JW, Gross RA, MacDonald RL. The peptide CGRP increases a high-threshold Ca2+ current in rat nodose neurones via a pertussis toxin-sensitive pathway. The Journal of Physiology. 455: 367-81. PMID 1336552  1
1991 Kelly KM, Gross RA, Macdonald RL. Tetrahydroaminoacridine (THA) reduces voltage-dependent calcium currents in rat sensory neurons. Neuroscience Letters. 132: 247-50. PMID 1784428 DOI: 10.1016/0304-3940(91)90312-H  1
1990 Wiley JW, Gross RA, Lu YX, Macdonald RL. Neuropeptide Y reduces calcium current and inhibits acetylcholine release in nodose neurons via a pertussis toxin-sensitive mechanism. Journal of Neurophysiology. 63: 1499-507. PMID 2358888  1
1990 Gross RA, Uhler MD, Macdonald RL. The cyclic AMP-dependent protein kinase catalytic subunit selectively enhances calcium currents in rat nodose neurones. The Journal of Physiology. 429: 483-96. PMID 2177506  1
1990 Kelly KM, Gross RA, Macdonald RL. Valproic acid selectively reduces the low-threshold (T) calcium current in rat nodose neurons. Neuroscience Letters. 116: 233-8. PMID 2175404 DOI: 10.1016/0304-3940(90)90416-7  1
1990 Gross RA, Wiley JW, Ryan-Jastrow T, Macdonald RL. Regulation by GTP and its stable thiol derivatives of calcium current components in rat nodose ganglion neurons. Molecular Pharmacology. 37: 546-53. PMID 2157961  1
1990 Gross RA, Moises HC, Uhler MD, Macdonald RL. Dynorphin A and cAMP-dependent protein kinase independently regulate neuronal calcium currents. Proceedings of the National Academy of Sciences of the United States of America. 87: 7025-9. PMID 1976250  1
1990 Gross RA, Uhler MD, Macdonald RL. The reduction of neuronal calcium currents by ATP-gamma-S is mediated by a G protein and occurs independently of cyclic AMP-dependent protein kinase. Brain Research. 535: 214-20. PMID 1963568 DOI: 10.1016/0006-8993(90)91603-E  1
1989 Gross RA, MacDonald RL. Activators of protein kinase C selectively enhance inactivation of a calcium current component of cultured sensory neurons in a pertussis toxin-sensitive manner. Journal of Neurophysiology. 61: 1259-69. PMID 2746325  1
1989 Gross RA, Macdonald RL, Ryan-Jastrow T. 2-Chloroadenosine reduces the N calcium current of cultured mouse sensory neurones in a pertussis toxin-sensitive manner. The Journal of Physiology. 411: 585-95. PMID 2614735  1
1989 Gross RA, Macdonald RL. Cyclic AMP selectively reduces the N-type calcium current component of mouse sensory neurons in culture by enhancing inactivation. Journal of Neurophysiology. 61: 97-105. PMID 2537387  1
1988 Gross RA, Macdonald RL. Differential actions of pentobarbitone on calcium current components of mouse sensory neurones in culture. The Journal of Physiology. 405: 187-203. PMID 2855640  1
1988 Gross RA, Macdonald RL. Reduction of the same calcium current component by A and C kinases: differential pertussis toxin sensitivity. Neuroscience Letters. 88: 50-6. PMID 2456492 DOI: 10.1016/0304-3940(88)90314-X  1
1988 Gross RA, Macdonald RL. Barbiturates and nifedipine have different and selective effects on calcium currents of mouse DRG neurons in culture: a possible basis for differing clinical actions. The 1987 S. Weir Mitchell award. Neurology. 38: 443-51. PMID 2450304  1
1987 Gross RA, Macdonald RL. Dynorphin A selectively reduces a large transient (N-type) calcium current of mouse dorsal root ganglion neurons in cell culture. Proceedings of the National Academy of Sciences of the United States of America. 84: 5469-73. PMID 2440050  1
1986 Macdonald RL, Weddle MG, Gross RA. Benzodiazepine, beta-carboline, and barbiturate actions on GABA responses. Advances in Biochemical Psychopharmacology. 41: 67-78. PMID 2874695  1
1983 Nelson PG, Marshall KC, Pun RY, Christian CN, Sheriff WH, Macdonald RL, Neale EA. Synaptic interactions between mammalian central neurons in cell culture. II. Quantal Analysis of EPSPs. Journal of Neurophysiology. 49: 1442-58. PMID 6875632  1
1983 Macdonald RL, Pun RY, Neale EA, Nelson PG. Synaptic interactions between mammalian central neurons in cell culture. I. Reversal potential for excitatory postsynaptic potentials. Journal of Neurophysiology. 49: 1428-41. PMID 6875631  1
1983 Nowak LM, Macdonald RL. Muscarine-sensitive voltage-dependent potassium current in cultured murine spinal cord neurons. Neuroscience Letters. 35: 85-91. PMID 6843894 DOI: 10.1016/0304-3940(83)90531-1  1
1983 Nowak LM, Macdonald RL. Ionic mechanism of muscarinic cholinergic depolarization of mouse spinal cord neurons in cell culture. Journal of Neurophysiology. 49: 792-803. PMID 6834099  1
1983 Bergey GK, MacDonald RL, Habig WH, Hardegree MC, Nelson PG. Tetanus toxin: convulsant action on mouse spinal cord neurons in culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 3: 2310-23. PMID 6631482  1
1983 Neale EA, Nelson PG, Macdonald RL, Christian CN, Bowers LM. Synaptic interactions between mammalian central neurons in cell culture. III. Morphophysiological correlates of quantal synaptic transmission. Journal of Neurophysiology. 49: 1459-68. PMID 6308178  1
1982 Neale EA, Moonen G, Macdonald RL, Nelson PG. Cerebellar macroneurons in microexplant cell culture: ultrastructural morphology. Neuroscience. 7: 1879-90. PMID 7133404 DOI: 10.1016/0306-4522(82)90004-5  1
1982 Heyer EJ, Nowak LM, Macdonald RL. Membrane depolarization and prolongation of calcium-dependent action potentials of mouse neurons in cell culture by two convulsants: bicuculline and penicillin. Brain Research. 232: 41-56. PMID 7055710 DOI: 10.1016/0006-8993(82)90609-6  1
1982 Moonen G, Neale EA, Macdonald RL, Gibbs W, Nelson PG. Cerebellar macroneurons in microexplant cell culture. Methodology, basic electrophysiology, and morphology after horseradish peroxidase injection. Brain Research. 281: 59-73. PMID 6291726 DOI: 10.1016/0165-3806(82)90113-4  1
1982 Nowak LM, Young AB, Macdonald RL. GABA and bicuculline actions on mouse spinal cord and cortical neurons in cell culture. Brain Research. 244: 155-64. PMID 6288177 DOI: 10.1016/0006-8993(82)90913-1  1
1982 Nowak LM, Macdonald RL. Substance P: ionic basis for depolarizing responses of mouse spinal cord neurons in cell culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 2: 1119-28. PMID 6180151  1
1982 Macdonald RL, Moonen G, Neale EA, Nelson PG. Cerebellar macroneurons in microexplant cell culture. Postsynaptic amino acid pharmacology. Brain Research. 281: 75-88. PMID 6128065 DOI: 10.1016/0165-3806(82)90114-6  1
1981 Heyer EJ, MacDonald RL, Bergey GK, Nelson PG. Calcium-dependent action potentials in mouse spinal cord neurons in cell culture. Brain Research. 220: 408-15. PMID 7284766 DOI: 10.1016/0006-8993(81)91234-8  1
1981 Heyer EJ, Nowak LM, Macdonald RL. Bicuculline: a convulsant with synaptic and nonsynaptic actions. Neurology. 31: 1381-90. PMID 7198187  1
1981 Nowak LM, MacDonald RL. Substance P decreases a potassium conductance of spinal cord neurons in cell culture. Brain Research. 214: 416-23. PMID 6165445 DOI: 10.1016/0006-8993(81)91205-1  1
1981 Macdonald RL, Nowak LM. Substance P and somatostatin actions on spinal cord neurons in primary dissociated cell culture. Advances in Biochemical Psychopharmacology. 28: 159-73. PMID 6163331  1
1980 Neale EA, MacDonald RL, Nelson PG. An inhibitory spinal cord neuron. Jama. 244: 2555. PMID 7431596 DOI: 10.1001/jama.1980.03310220053031  1
1980 Macdonald RL, Nowak LM. Somatostatin actions in primary dissociated cell cultures of mammalian spinal cord neurons. International Journal of Neurology. 14: 221-32. PMID 6152909  1
1978 Nelson PG, Neale EA, Macdonald RL. Formation and modification of synapses in central nervous system cell cultures. Federation Proceedings. 37: 2010-5. PMID 565301  1
1978 Neale EA, Macdonald RL, Nelson PG. Intracellular horseradish peroxidase injection for correlation of light and electron microscopic anatomy with synaptic physiology of cultured mouse spinal cord neurons. Brain Research. 152: 265-82. PMID 209872 DOI: 10.1016/0006-8993(78)90255-X  1
1978 Macdonald RL, Nelson PG. Specific-opiate-induced depression of transmitter release from dorsal root ganglion cells in culture. Science (New York, N.Y.). 199: 1449-51. PMID 204015  1
1976 Cohen DH, MacDonald RL. Involvement of the avian hypothalamus in defensively conditioned heart rate change. The Journal of Comparative Neurology. 167: 465-80. PMID 1270630 DOI: 10.1002/cne.901670405  0.48
1973 Macdonald RL, Cohen DH. Heart rate and blood pressure responses to electrical stimulation of the central nervous system in the pigeon (Columba livia). The Journal of Comparative Neurology. 150: 109-36. PMID 4579121 DOI: 10.1002/cne.901500202  1
1971 Cohen DH, Macdonald RL. Some variables affecting orienting and conditioned heart-rate responses in the pigeon. Journal of Comparative and Physiological Psychology. 74: 123-33. PMID 5163697 DOI: 10.1037/h0030326  1
1970 Macdonald RL, Cohen DH. Cells of origin of sympathetic pre- and postganglionic cardioacceleratory fibers in the pigeon. The Journal of Comparative Neurology. 140: 343-58. PMID 5476888 DOI: 10.1002/cne.901400307  1
1970 Cohen DH, Schnall AM, Macdonald RL, Pitts LH. Medullary cells of origin of vagal cardioinhibitory fibers in the pigeon. I. Anatomical studies of peripheral vagus nerve and the dorsal motor nucleus. The Journal of Comparative Neurology. 140: 299-320. PMID 5476886 DOI: 10.1002/cne.901400305  1
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