| Year |
Citation |
Score |
| 2024 |
Potesta CV, Cargile MS, Yan A, Xiong S, Macdonald RL, Gallagher MJ, Zhou C. Preoptic area controls sleep-related seizure onset in a genetic epilepsy mouse model. Biorxiv : the Preprint Server For Biology. PMID 39314442 DOI: 10.1101/2023.11.24.568593 |
0.692 |
|
| 2023 |
Hernandez CC, Hu N, Shen W, Macdonald RL. Epileptic Encephalopathy Structural Variants Share Common Gating and Trafficking Defects. Biomolecules. 13. PMID 38136660 DOI: 10.3390/biom13121790 |
0.414 |
|
| 2023 |
Hernandez CC, Shen Y, Hu N, Shen W, Narayanan V, Ramsey K, He W, Zou L, Macdonald RL. Variants Associated with Febrile Seizures. Biomolecules. 13. PMID 36979350 DOI: 10.3390/biom13030414 |
0.358 |
|
| 2022 |
Catron MA, Howe RK, Besing GK, St John EK, Potesta CV, Gallagher MJ, Macdonald RL, Zhou C. Sleep slow-wave oscillations trigger seizures in a genetic epilepsy model of Dravet syndrome. Brain Communications. 5: fcac332. PMID 36632186 DOI: 10.1093/braincomms/fcac332 |
0.692 |
|
| 2022 |
Qu S, Jackson LG, Zhou C, Shen D, Shen W, Nwosu G, Howe R, Caltron M, Flamm C, Biven M, Kang JQ, Macdonald RL. Heterozygous GABA receptor β3 subunit N110D knock-in mice have epileptic spasms. Epilepsia. PMID 36495145 DOI: 10.1111/epi.17470 |
0.753 |
|
| 2021 |
Qu S, Zhou C, Howe R, Shen W, Huang X, Catron M, Hu N, Macdonald RL. The K328M substitution in the human GABA receptor gamma2 subunit causes GEFS+ and premature sudden death in knock-in mice. Neurobiology of Disease. 105296. PMID 33582225 DOI: 10.1016/j.nbd.2021.105296 |
0.788 |
|
| 2020 |
Shen D, Chen J, Liu D, Shen M, Wang X, Wu Y, Ke S, Macdonald RL, Zhang Q. The F343L allele causes spontaneous seizures in a novel transgenic zebrafish model that can be treated with suberanilohydroxamic acid (SAHA). Annals of Translational Medicine. 8: 1560. PMID 33437759 DOI: 10.21037/atm-20-3745 |
0.379 |
|
| 2020 |
Shen W, Poliquin S, Macdonald RL, Dong M, Kang JQ. Endoplasmic reticulum stress increases inflammatory cytokines in an epilepsy mouse model Gabrg2 knockin: A link between genetic and acquired epilepsy? Epilepsia. PMID 32944937 DOI: 10.1111/epi.16670 |
0.388 |
|
| 2020 |
Zhang CQ, Catron MA, Ding L, Hanna CM, Gallagher MJ, Macdonald RL, Zhou C. Impaired State-Dependent Potentiation of GABAergic Synaptic Currents Triggers Seizures in a Genetic Generalized Epilepsy Model. Cerebral Cortex (New York, N.Y. : 1991). PMID 32930324 DOI: 10.1093/Cercor/Bhaa256 |
0.738 |
|
| 2020 |
Qu S, Catron M, Zhou C, Janve V, Shen W, Howe RK, Macdonald RL. GABA receptor β3 subunit mutation D120N causes Lennox-Gastaut syndrome in knock-in mice. Brain Communications. 2: fcaa028. PMID 32467926 DOI: 10.1093/braincomms/fcaa028 |
0.75 |
|
| 2019 |
Shi YW, Zhang Q, Cai K, Poliquin S, Shen W, Winters N, Yi YH, Wang J, Hu N, Macdonald RL, Liao WP, Kang JQ. Synaptic clustering differences due to different GABRB3 mutations cause variable epilepsy syndromes. Brain : a Journal of Neurology. PMID 31435640 DOI: 10.1093/brain/awz250 |
0.46 |
|
| 2019 |
Zhang CQ, McMahon B, Dong H, Warner T, Shen W, Gallagher M, Macdonald RL, Kang JQ. Molecular basis for and chemogenetic modulation of comorbidities in GABRG2-deficient epilepsies. Epilepsia. PMID 31087664 DOI: 10.1111/Epi.15160 |
0.432 |
|
| 2019 |
Hernandez CC, XiangWei W, Hu N, Shen D, Shen W, Lagrange AH, Zhang Y, Dai L, Ding C, Sun Z, Hu J, Zhu H, Jiang Y, Macdonald RL. Altered inhibitory synapses in de novo GABRA5 and GABRA1 mutations associated with early onset epileptic encephalopathies. Brain : a Journal of Neurology. PMID 31056671 DOI: 10.1093/Brain/Awz123 |
0.45 |
|
| 2019 |
Hernandez CC, Macdonald RL. A Structural Look at GABA Receptor Mutations Linked to Epilepsy Syndromes. Brain Research. PMID 30851244 DOI: 10.1016/J.Brainres.2019.03.004 |
0.487 |
|
| 2018 |
Lagrange AH, Hu N, Macdonald RL. GABA beyond the synapse-defining the subtype-specific pharmacodynamics of nonsynaptic GABA receptors. The Journal of Physiology. PMID 30019335 DOI: 10.1113/JP276187 |
0.459 |
|
| 2018 |
Wang CH, Hernandez CC, Wu J, Zhou N, Hsu HY, Shen ML, Wang YC, Macdonald RL, Wu DC. A missense mutation A384P associated with human hyperekplexia reveals a desensitization site of glycine receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 29440552 DOI: 10.1523/Jneurosci.0674-16.2018 |
0.466 |
|
| 2017 |
Hernandez CC, Zhang Y, Hu N, Shen D, Shen W, Liu X, Kong W, Jiang Y, Macdonald RL. GABA A Receptor Coupling Junction and Pore GABRB3 Mutations are Linked to Early-Onset Epileptic Encephalopathy. Scientific Reports. 7: 15903. PMID 29162865 DOI: 10.1038/S41598-017-16010-3 |
0.47 |
|
| 2017 |
Huang X, Zhou C, Tian M, Kang JQ, Shen W, Verdier K, Pimenta A, MacDonald RL. Overexpressing wild-type γ2 subunits rescued the seizure phenotype in Gabrg2(+/Q390X) Dravet syndrome mice. Epilepsia. PMID 28586508 DOI: 10.1111/Epi.13810 |
0.807 |
|
| 2017 |
Hernandez CC, Kong W, Hu N, Zhang Y, Shen W, Jackson L, Liu X, Jiang Y, Macdonald RL. Altered Channel Conductance States and Gating of GABAA Receptors by a Pore Mutation Linked to Dravet Syndrome. Eneuro. 4. PMID 28197552 DOI: 10.1523/ENEURO.0251-16.2017 |
0.423 |
|
| 2016 |
Hernandez CC, Klassen TL, Jackson LG, Gurba K, Hu N, Noebels JL, Macdonald RL. Correction: Deleterious Rare Variants Reveal Risk for Loss of GABAA Receptor Function in Patients with Genetic Epilepsy and in the General Population. Plos One. 11: e0167264. PMID 27870904 DOI: 10.1371/journal.pone.0167264 |
0.777 |
|
| 2016 |
Shen D, Hernandez CC, Shen W, Hu N, Poduri A, Shiedley B, Rotenberg A, Datta AN, Leiz S, Patzer S, Boor R, Ramsey K, Goldberg E, Helbig I, Ortiz-Gonzalez XR, ... ... Macdonald RL, et al. De novo GABRG2 mutations associated with epileptic encephalopathies. Brain : a Journal of Neurology. PMID 27864268 DOI: 10.1093/Brain/Aww272 |
0.487 |
|
| 2016 |
Ishii A, Kang JQ, Schornak CC, Hernandez CC, Shen W, Watkins JC, Macdonald RL, Hirose S. A de novo missense mutation of GABRB2 causes early myoclonic encephalopathy. Journal of Medical Genetics. PMID 27789573 DOI: 10.1136/Jmedgenet-2016-104083 |
0.326 |
|
| 2016 |
Wang J, Shen D, Xia G, Shen W, Macdonald RL, Xu D, Kang JQ. Differential protein structural disturbances and suppression of assembly partners produced by nonsense GABRG2 epilepsy mutations: implications for disease phenotypic heterogeneity. Scientific Reports. 6: 35294. PMID 27762395 DOI: 10.1038/srep35294 |
0.46 |
|
| 2016 |
Hernandez CC, Klassen TL, Jackson LG, Gurba K, Hu N, Noebels JL, Macdonald RL. Deleterious Rare Variants Reveal Risk for Loss of GABAA Receptor Function in Patients with Genetic Epilepsy and in the General Population. Plos One. 11: e0162883. PMID 27622563 DOI: 10.1371/Journal.Pone.0162883 |
0.816 |
|
| 2016 |
Botzolakis EJ, Gurba KN, Lagrange AH, Feng HJ, Stanic AK, Hu N, Macdonald RL. Comparison of GABA-A Receptor αβγ and αβδ Expression Using Flow Cytometry and Electrophysiology: Evidence for Alternate Subunit Stoichiometries and Arrangements. The Journal of Biological Chemistry. PMID 27493204 DOI: 10.1074/Jbc.M115.698860 |
0.795 |
|
| 2016 |
Kang JQ, Macdonald RL. Molecular Pathogenic Basis for GABRG2 Mutations Associated With a Spectrum of Epilepsy Syndromes, From Generalized Absence Epilepsy to Dravet Syndrome. Jama Neurology. PMID 27367160 DOI: 10.1001/jamaneurol.2016.0449 |
0.383 |
|
| 2016 |
Warner TA, Shen W, Huang X, Liu Z, Macdonald RL, Kang JQ. DIfferential molecular and behavioral alterations in mouse models of GABRG2 haploinsufficiency versus dominant negative mutations associated with human epilepsy. Human Molecular Genetics. PMID 27340224 DOI: 10.1093/Hmg/Ddw168 |
0.542 |
|
| 2016 |
Janve VS, Hernandez CC, Verdier KM, Hu N, Macdonald RL. Epileptic encephalopathy de novo GABRB mutations impair GABAA receptor function. Annals of Neurology. PMID 26950270 DOI: 10.1002/Ana.24631 |
0.431 |
|
| 2015 |
Kang JQ, Shen W, Zhou C, Xu D, Macdonald RL. The human epilepsy mutation GABRG2(Q390X) causes chronic subunit accumulation and neurodegeneration. Nature Neuroscience. 18: 988-96. PMID 26005849 DOI: 10.1038/Nn.4024 |
0.775 |
|
| 2014 |
Todd E, Gurba KN, Botzolakis EJ, Stanic AK, Macdonald RL. GABAA receptor biogenesis is impaired by the γ2 subunit febrile seizure-associated mutation, GABRG2(R177G). Neurobiology of Disease. 69: 215-24. PMID 24874541 DOI: 10.1016/j.nbd.2014.05.013 |
0.824 |
|
| 2014 |
Huang X, Hernandez CC, Hu N, Macdonald RL. Three epilepsy-associated GABRG2 missense mutations at the γ+/β- interface disrupt GABAA receptor assembly and trafficking by similar mechanisms but to different extents. Neurobiology of Disease. 68: 167-79. PMID 24798517 DOI: 10.1016/J.Nbd.2014.04.015 |
0.603 |
|
| 2014 |
Johnston AJ, Kang JQ, Shen W, Pickrell WO, Cushion TD, Davies JS, Baer K, Mullins JG, Hammond CL, Chung SK, Thomas RH, White C, Smith PE, Macdonald RL, Rees MI. A novel GABRG2 mutation, p.R136*, in a family with GEFS+ and extended phenotypes. Neurobiology of Disease. 64: 131-41. PMID 24407264 DOI: 10.1016/J.Nbd.2013.12.013 |
0.409 |
|
| 2014 |
Lo WY, Lagrange AH, Hernandez CC, Gurba KN, Macdonald RL. Co-expression of γ2 subunits hinders processing of N-linked glycans attached to the N104 glycosylation sites of GABAA receptor β2 subunits. Neurochemical Research. 39: 1088-103. PMID 24213971 DOI: 10.1007/S11064-013-1187-9 |
0.821 |
|
| 2013 |
Kang JQ, Shen W, Macdonald RL. Trafficking-deficient mutant GABRG2 subunit amount may modify epilepsy phenotype. Annals of Neurology. 74: 547-59. PMID 23720301 DOI: 10.1002/ana.23947 |
0.431 |
|
| 2013 |
Tian M, Mei D, Freri E, Hernandez CC, Granata T, Shen W, Macdonald RL, Guerrini R. Impaired surface αβγ GABA(A) receptor expression in familial epilepsy due to a GABRG2 frameshift mutation. Neurobiology of Disease. 50: 135-41. PMID 23069679 DOI: 10.1016/J.Nbd.2012.10.008 |
0.707 |
|
| 2013 |
Hernandez CC, Gurba KN, Hu N, Macdonald RL. GAbAA Receptor Subunit Rare Variants Identified in Patients with Idiopathic Generalized Epilepsy Alter Receptor Gating and Assembly Biophysical Journal. 104: 275a. DOI: 10.1016/J.Bpj.2012.11.1541 |
0.824 |
|
| 2012 |
Macdonald RL, Kang JQ. mRNA surveillance and endoplasmic reticulum quality control processes alter biogenesis of mutant GABAA receptor subunits associated with genetic epilepsies. Epilepsia. 53: 59-70. PMID 23216579 DOI: 10.1111/epi.12035 |
0.522 |
|
| 2012 |
Porter RJ, Dhir A, Macdonald RL, Rogawski MA. Mechanisms of action of antiseizure drugs. Handbook of Clinical Neurology. 108: 663-81. PMID 22939059 DOI: 10.1016/B978-0-444-52899-5.00021-6 |
0.369 |
|
| 2012 |
Huang X, Tian M, Hernandez CC, Hu N, Macdonald RL. The GABRG2 nonsense mutation, Q40X, associated with Dravet syndrome activated NMD and generated a truncated subunit that was partially rescued by aminoglycoside-induced stop codon read-through. Neurobiology of Disease. 48: 115-23. PMID 22750526 DOI: 10.1016/J.Nbd.2012.06.013 |
0.75 |
|
| 2012 |
Wu X, Wu Z, Ning G, Guo Y, Ali R, Macdonald RL, De Blas AL, Luscher B, Chen G. γ-Aminobutyric acid type A (GABAA) receptor α subunits play a direct role in synaptic versus extrasynaptic targeting. The Journal of Biological Chemistry. 287: 27417-30. PMID 22711532 DOI: 10.1074/Jbc.M112.360461 |
0.479 |
|
| 2012 |
Tian M, Macdonald RL. The intronic GABRG2 mutation, IVS6+2T->G, associated with childhood absence epilepsy altered subunit mRNA intron splicing, activated nonsense-mediated decay, and produced a stable truncated γ2 subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 5937-52. PMID 22539854 DOI: 10.1523/JNEUROSCI.5332-11.2012 |
0.668 |
|
| 2012 |
Gurba KN, Hernandez CC, Hu N, Macdonald RL. GABRB3 mutation, G32R, associated with childhood absence epilepsy alters α1β3γ2L γ-aminobutyric acid type A (GABAA) receptor expression and channel gating. The Journal of Biological Chemistry. 287: 12083-97. PMID 22303015 DOI: 10.1074/Jbc.M111.332528 |
0.839 |
|
| 2012 |
Hernandez CC, Gurba KN, Hu N, Macdonald RL. Mapping GABAA Receptor Single Nucleotide Polymorphisms (SNPs) Linked to Epilepsy: Insights into the Receptor Gating and Assembly Biophysical Journal. 102: 111a. DOI: 10.1016/J.Bpj.2011.11.624 |
0.818 |
|
| 2011 |
Hernandez CC, Gurba KN, Hu N, Macdonald RL. The GABRA6 mutation, R46W, associated with childhood absence epilepsy, alters 6β22 and 6β2 GABA(A) receptor channel gating and expression. The Journal of Physiology. 589: 5857-78. PMID 21930603 DOI: 10.1113/Jphysiol.2011.218883 |
0.844 |
|
| 2011 |
Botzolakis EJ, Zhao J, Gurba KN, Macdonald RL, Hedera P. The effect of HSP-causing mutations in SPG3A and NIPA1 on the assembly, trafficking, and interaction between atlastin-1 and NIPA1. Molecular and Cellular Neurosciences. 46: 122-35. PMID 20816793 DOI: 10.1016/j.mcn.2010.08.012 |
0.771 |
|
| 2011 |
Delahanty RJ, Kang JQ, Brune CW, Kistner EO, Courchesne E, Cox NJ, Cook EH, Macdonald RL, Sutcliffe JS. Maternal transmission of a rare GABRB3 signal peptide variant is associated with autism. Molecular Psychiatry. 16: 86-96. PMID 19935738 DOI: 10.1038/Mp.2009.118 |
0.387 |
|
| 2011 |
Hernandez CC, Gurba KN, Hu N, Macdonald RL. A novel Polymorphism Linked to Epilepsy Encoding a Missense Mutation in the Pre-M1 Region of a6 Subunits Alters the Gating, but not Trafficking, of GABAa Receptors Biophysical Journal. 100: 271a-272a. DOI: 10.1016/J.Bpj.2010.12.1692 |
0.834 |
|
| 2010 |
Kang JQ, Shen W, Lee M, Gallagher MJ, Macdonald RL. Slow degradation and aggregation in vitro of mutant GABAA receptor gamma2(Q351X) subunits associated with epilepsy. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 13895-905. PMID 20943930 DOI: 10.1523/JNEUROSCI.2320-10.2010 |
0.44 |
|
| 2010 |
Lo WY, Lagrange AH, Hernandez CC, Harrison R, Dell A, Haslam SM, Sheehan JH, Macdonald RL. Glycosylation of {beta}2 subunits regulates GABAA receptor biogenesis and channel gating. The Journal of Biological Chemistry. 285: 31348-61. PMID 20639197 DOI: 10.1074/Jbc.M110.151449 |
0.495 |
|
| 2010 |
Ding L, Feng HJ, Macdonald RL, Botzolakis EJ, Hu N, Gallagher MJ. GABA(A) receptor alpha1 subunit mutation A322D associated with autosomal dominant juvenile myoclonic epilepsy reduces the expression and alters the composition of wild type GABA(A) receptors. The Journal of Biological Chemistry. 285: 26390-405. PMID 20551311 DOI: 10.1074/Jbc.M110.142299 |
0.807 |
|
| 2010 |
Feng HJ, Macdonald RL. Barbiturates require the N terminus and first transmembrane domain of the delta subunit for enhancement of alpha1beta3delta GABAA receptor currents. The Journal of Biological Chemistry. 285: 23614-21. PMID 20525684 DOI: 10.1074/Jbc.M110.122564 |
0.502 |
|
| 2010 |
Macdonald RL, Kang JQ, Gallagher MJ. Mutations in GABAA receptor subunits associated with genetic epilepsies. The Journal of Physiology. 588: 1861-9. PMID 20308251 DOI: 10.1113/jphysiol.2010.186999 |
0.44 |
|
| 2010 |
Tang X, Hernandez CC, Macdonald RL. Modulation of spontaneous and GABA-evoked tonic alpha4beta3delta and alpha4beta3gamma2L GABAA receptor currents by protein kinase A. Journal of Neurophysiology. 103: 1007-19. PMID 19939957 DOI: 10.1152/Jn.00801.2009 |
0.588 |
|
| 2010 |
MacDonald RL, Kang JQ, Gallagher MJ. Genetic epilepsies and GABAA receptor mutations Epilepsia. 51: 64. DOI: 10.1111/j.1528-1167.2010.02850.x |
0.517 |
|
| 2010 |
Macdonald RL, Botzolakis EJ. GABAA receptor channels Physiology and Pathology of Chloride Transporters and Channels in the Nervous System. 257-282. DOI: 10.1016/B978-0-12-374373-2.00014-5 |
0.768 |
|
| 2009 |
Belelli D, Harrison NL, Maguire J, Macdonald RL, Walker MC, Cope DW. Extrasynaptic GABAA receptors: form, pharmacology, and function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 12757-63. PMID 19828786 DOI: 10.1523/Jneurosci.3340-09.2009 |
0.486 |
|
| 2009 |
Kang JQ, Macdonald RL. Making sense of nonsense GABA(A) receptor mutations associated with genetic epilepsies. Trends in Molecular Medicine. 15: 430-8. PMID 19717338 DOI: 10.1016/j.molmed.2009.07.003 |
0.51 |
|
| 2009 |
Bianchi MT, Botzolakis EJ, Lagrange AH, Macdonald RL. Benzodiazepine modulation of GABA(A) receptor opening frequency depends on activation context: a patch clamp and simulation study. Epilepsy Research. 85: 212-20. PMID 19447010 DOI: 10.1016/j.eplepsyres.2009.03.007 |
0.83 |
|
| 2009 |
Lewis AS, Schwartz E, Chan CS, Noam Y, Shin M, Wadman WJ, Surmeier DJ, Baram TZ, Macdonald RL, Chetkovich DM. Alternatively spliced isoforms of TRIP8b differentially control h channel trafficking and function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 6250-65. PMID 19439603 DOI: 10.1523/Jneurosci.0856-09.2009 |
0.331 |
|
| 2009 |
Macdonald RL, Kang JQ. Molecular pathology of genetic epilepsies associated with GABAA receptor subunit mutations. Epilepsy Currents / American Epilepsy Society. 9: 18-23. PMID 19396344 DOI: 10.1111/j.1535-7511.2008.01278.x |
0.469 |
|
| 2009 |
Kang JQ, Shen W, Macdonald RL. The GABRG2 mutation, Q351X, associated with generalized epilepsy with febrile seizures plus, has both loss of function and dominant-negative suppression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2845-56. PMID 19261880 DOI: 10.1523/JNEUROSCI.4772-08.2009 |
0.463 |
|
| 2009 |
Kang JQ, Shen W, Macdonald RL. Two molecular pathways (NMD and ERAD) contribute to a genetic epilepsy associated with the GABA(A) receptor GABRA1 PTC mutation, 975delC, S326fs328X. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 2833-44. PMID 19261879 DOI: 10.1523/JNEUROSCI.4512-08.2009 |
0.456 |
|
| 2009 |
Botzolakis EJ, Maheshwari A, Feng HJ, Lagrange AH, Shaver JH, Kassebaum NJ, Venkataraman R, Baudenbacher F, Macdonald RL. Achieving synaptically relevant pulses of neurotransmitter using PDMS microfluidics. Journal of Neuroscience Methods. 177: 294-302. PMID 19013195 DOI: 10.1016/j.jneumeth.2008.10.014 |
0.783 |
|
| 2009 |
Feng HJ, Botzolakis EJ, Macdonald RL. Context-dependent modulation of alphabetagamma and alphabetadelta GABA A receptors by penicillin: implications for phasic and tonic inhibition. Neuropharmacology. 56: 161-73. PMID 18775733 DOI: 10.1016/J.Neuropharm.2008.08.010 |
0.826 |
|
| 2008 |
Zhao J, Matthies DS, Botzolakis EJ, Macdonald RL, Blakely RD, Hedera P. Hereditary spastic paraplegia-associated mutations in the NIPA1 gene and its Caenorhabditis elegans homolog trigger neural degeneration in vitro and in vivo through a gain-of-function mechanism. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13938-51. PMID 19091982 DOI: 10.1523/JNEUROSCI.4668-08.2008 |
0.769 |
|
| 2008 |
Lo WY, Botzolakis EJ, Tang X, Macdonald RL. A conserved Cys-loop receptor aspartate residue in the M3-M4 cytoplasmic loop is required for GABAA receptor assembly. The Journal of Biological Chemistry. 283: 29740-52. PMID 18723504 DOI: 10.1074/Jbc.M802856200 |
0.814 |
|
| 2008 |
Rula EY, Lagrange AH, Jacobs MM, Hu N, Macdonald RL, Emeson RB. Developmental modulation of GABA(A) receptor function by RNA editing. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 6196-201. PMID 18550761 DOI: 10.1523/Jneurosci.0443-08.2008 |
0.48 |
|
| 2008 |
Tanaka M, Olsen RW, Medina MT, Schwartz E, Alonso ME, Duron RM, Castro-Ortega R, Martinez-Juarez IE, Pascual-Castroviejo I, Machado-Salas J, Silva R, Bailey JN, Bai D, Ochoa A, Jara-Prado A, ... ... Macdonald RL, et al. Hyperglycosylation and reduced GABA currents of mutated GABRB3 polypeptide in remitting childhood absence epilepsy. American Journal of Human Genetics. 82: 1249-61. PMID 18514161 DOI: 10.1016/j.ajhg.2008.04.020 |
0.444 |
|
| 2008 |
Feng HJ, Mathews GC, Kao C, Macdonald RL. Alterations of GABA A-receptor function and allosteric modulation during development of status epilepticus. Journal of Neurophysiology. 99: 1285-93. PMID 18216225 DOI: 10.1152/Jn.01180.2007 |
0.432 |
|
| 2007 |
Bianchi MT, Botzolakis EJ, Haas KF, Fisher JL, Macdonald RL. Microscopic kinetic determinants of macroscopic currents: insights from coupling and uncoupling of GABAA receptor desensitization and deactivation. The Journal of Physiology. 584: 769-87. PMID 17884921 DOI: 10.1113/jphysiol.2007.142364 |
0.818 |
|
| 2007 |
Gallagher MJ, Ding L, Maheshwari A, Macdonald RL. The GABAA receptor alpha1 subunit epilepsy mutation A322D inhibits transmembrane helix formation and causes proteasomal degradation. Proceedings of the National Academy of Sciences of the United States of America. 104: 12999-3004. PMID 17670950 DOI: 10.1073/pnas.0700163104 |
0.356 |
|
| 2007 |
Lagrange AH, Botzolakis EJ, Macdonald RL. Enhanced macroscopic desensitization shapes the response of alpha4 subtype-containing GABAA receptors to synaptic and extrasynaptic GABA. The Journal of Physiology. 578: 655-76. PMID 17124266 DOI: 10.1113/jphysiol.2006.122135 |
0.825 |
|
| 2006 |
Macdonald RL, Kang JQ, Gallagher MJ, Feng HJ. GABA(A) receptor mutations associated with generalized epilepsies. Advances in Pharmacology (San Diego, Calif.). 54: 147-69. PMID 17175814 DOI: 10.1016/S1054-3589(06)54007-4 |
0.546 |
|
| 2006 |
Audenaert D, Schwartz E, Claeys KG, Claes L, Deprez L, Suls A, Van Dyck T, Lagae L, Van Broeckhoven C, Macdonald RL, De Jonghe P. A novel GABRG2 mutation associated with febrile seizures. Neurology. 67: 687-90. PMID 16924025 DOI: 10.1212/01.wnl.0000230145.73496.a2 |
0.438 |
|
| 2006 |
Kang JQ, Shen W, Macdonald RL. Why does fever trigger febrile seizures? GABAA receptor gamma2 subunit mutations associated with idiopathic generalized epilepsies have temperature-dependent trafficking deficiencies. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 2590-7. PMID 16510738 DOI: 10.1523/JNEUROSCI.4243-05.2006 |
0.457 |
|
| 2006 |
Feng HJ, Kang JQ, Song L, Dibbens L, Mulley J, Macdonald RL. Delta subunit susceptibility variants E177A and R220H associated with complex epilepsy alter channel gating and surface expression of alpha4beta2delta GABAA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1499-506. PMID 16452673 DOI: 10.1523/Jneurosci.2913-05.2006 |
0.474 |
|
| 2005 |
Jones-Davis DM, Song L, Gallagher MJ, Macdonald RL. Structural determinants of benzodiazepine allosteric regulation of GABA(A) receptor currents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 8056-65. PMID 16135763 DOI: 10.1523/JNEUROSCI.0348-05.2005 |
0.804 |
|
| 2005 |
Gallagher MJ, Shen W, Song L, Macdonald RL. Endoplasmic reticulum retention and associated degradation of a GABAA receptor epilepsy mutation that inserts an aspartate in the M3 transmembrane segment of the alpha1 subunit. The Journal of Biological Chemistry. 280: 37995-8004. PMID 16123039 DOI: 10.1074/jbc.M508305200 |
0.352 |
|
| 2005 |
Rogawski MA, Macdonald RL, Pedley TA. Larry S. Benardo, MD, PhD 1956–2004 Epilepsy Currents. 5: 159-159. DOI: 10.1111/j.1535-7597.2005.20050704.x |
0.346 |
|
| 2005 |
Macdonald RL, Bianchi MT, Feng H. Corrigendum to “Mutations linked to generalized epilepsy in humans reduce GABAA receptor current” [Exp. Neurol. 184 (2003) S58–S67] Experimental Neurology. 191: 223. DOI: 10.1016/J.Expneurol.2004.08.029 |
0.625 |
|
| 2004 |
Karadsheh MS, Shah MS, Tang X, Macdonald RL, Stitzel JA. Functional characterization of mouse alpha4beta2 nicotinic acetylcholine receptors stably expressed in HEK293T cells. Journal of Neurochemistry. 91: 1138-50. PMID 15569257 DOI: 10.1111/J.1471-4159.2004.02801.X |
0.499 |
|
| 2004 |
Kang JQ, Kang J, Macdonald RL. The GABAA receptor gamma2 subunit R43Q mutation linked to childhood absence epilepsy and febrile seizures causes retention of alpha1beta2gamma2S receptors in the endoplasmic reticulum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 8672-7. PMID 15470132 DOI: 10.1523/JNEUROSCI.2717-04.2004 |
0.523 |
|
| 2004 |
Macdonald RL, Gallagher MJ, Feng HJ, Kang J. GABA(A) receptor epilepsy mutations. Biochemical Pharmacology. 68: 1497-506. PMID 15451392 DOI: 10.1016/J.Bcp.2004.07.029 |
0.512 |
|
| 2004 |
Feng HJ, Macdonald RL. Multiple actions of propofol on alphabetagamma and alphabetadelta GABAA receptors. Molecular Pharmacology. 66: 1517-24. PMID 15331770 DOI: 10.1124/Mol.104.003426 |
0.486 |
|
| 2004 |
Feng HJ, Bianchi MT, Macdonald RL. Pentobarbital differentially modulates alpha1beta3delta and alpha1beta3gamma2L GABAA receptor currents. Molecular Pharmacology. 66: 988-1003. PMID 15247320 DOI: 10.1124/Mol.104.002543 |
0.702 |
|
| 2004 |
Gallagher MJ, Song L, Arain F, Macdonald RL. The juvenile myoclonic epilepsy GABA(A) receptor alpha1 subunit mutation A322D produces asymmetrical, subunit position-dependent reduction of heterozygous receptor currents and alpha1 subunit protein expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 5570-8. PMID 15201329 DOI: 10.1523/JNEUROSCI.1301-04.2004 |
0.386 |
|
| 2004 |
Feng HJ, Macdonald RL. Proton modulation of alpha 1 beta 3 delta GABAA receptor channel gating and desensitization. Journal of Neurophysiology. 92: 1577-85. PMID 15152020 DOI: 10.1152/Jn.00285.2004 |
0.502 |
|
| 2004 |
Dibbens LM, Feng HJ, Richards MC, Harkin LA, Hodgson BL, Scott D, Jenkins M, Petrou S, Sutherland GR, Scheffer IE, Berkovic SF, Macdonald RL, Mulley JC. GABRD encoding a protein for extra- or peri-synaptic GABAA receptors is a susceptibility locus for generalized epilepsies. Human Molecular Genetics. 13: 1315-9. PMID 15115768 DOI: 10.1093/Hmg/Ddh146 |
0.504 |
|
| 2003 |
Hinkle DJ, Macdonald RL. Beta subunit phosphorylation selectively increases fast desensitization and prolongs deactivation of alpha1beta1gamma2L and alpha1beta3gamma2L GABA(A) receptor currents. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 11698-710. PMID 14684872 |
0.811 |
|
| 2003 |
Bianchi MT, Macdonald RL. Neurosteroids shift partial agonist activation of GABA(A) receptor channels from low- to high-efficacy gating patterns. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10934-43. PMID 14645489 DOI: 10.1523/Jneurosci.23-34-10934.2003 |
0.69 |
|
| 2003 |
Macdonald RL, Bianchi MT, Bianch MT, Feng H. Mutations linked to generalized epilepsy in humans reduce GABA(A) receptor current. Experimental Neurology. 184: S58-67. PMID 14597328 DOI: 10.1016/J.Expneurol.2003.08.011 |
0.711 |
|
| 2003 |
Kim H, Macdonald RL. An N-terminal histidine is the primary determinant of alpha subunit-dependent Cu2+ sensitivity of alphabeta3gamma2L GABA(A) receptors. Molecular Pharmacology. 64: 1145-52. PMID 14573764 DOI: 10.1124/mol.64.5.1145 |
0.348 |
|
| 2003 |
Hinkle DJ, Bianchi MT, Macdonald RL. Modifications of a commercial perfusion system for use in ultrafast solution exchange during patch clamp recording. Biotechniques. 35: 472-4, 476. PMID 14513550 |
0.758 |
|
| 2003 |
Kim H, Flanagin BA, Qin C, Macdonald RL, Stitzel JA. The mouse Chrna4 A529T polymorphism alters the ratio of high to low affinity alpha 4 beta 2 nAChRs. Neuropharmacology. 45: 345-54. PMID 12871652 DOI: 10.1016/S0028-3908(03)00167-9 |
0.396 |
|
| 2003 |
Jones-Davis DM, Macdonald RL. GABA(A) receptor function and pharmacology in epilepsy and status epilepticus. Current Opinion in Pharmacology. 3: 12-8. PMID 12550736 DOI: 10.1016/S1471-4892(02)00015-2 |
0.824 |
|
| 2003 |
Hinkle DJ, Macdonald RL. β Subunit Phosphorylation Selectively Increases Fast Desensitization and Prolongs Deactivation of α1β1γ2L and α1β3γ2L GABAAReceptor Currents The Journal of Neuroscience. 23: 11698-11710. DOI: 10.1523/JNEUROSCI.23-37-11698.2003 |
0.806 |
|
| 2002 |
Chen C, Bharucha V, Chen Y, Westenbroek RE, Brown A, Malhotra JD, Jones D, Avery C, Gillespie PJ, Kazen-Gillespie KA, Kazarinova-Noyes K, Shrager P, Saunders TL, Macdonald RL, Ransom BR, et al. Reduced sodium channel density, altered voltage dependence of inactivation, and increased susceptibility to seizures in mice lacking sodium channel beta 2-subunits. Proceedings of the National Academy of Sciences of the United States of America. 99: 17072-7. PMID 12481039 DOI: 10.1073/Pnas.212638099 |
0.364 |
|
| 2002 |
Bianchi MT, Haas KF, Macdonald RL. Alpha1 and alpha6 subunits specify distinct desensitization, deactivation and neurosteroid modulation of GABA(A) receptors containing the delta subunit. Neuropharmacology. 43: 492-502. PMID 12367596 DOI: 10.1016/S0028-3908(02)00163-6 |
0.708 |
|
| 2002 |
Bianchi MT, Macdonald RL. Slow phases of GABA(A) receptor desensitization: structural determinants and possible relevance for synaptic function. The Journal of Physiology. 544: 3-18. PMID 12356876 DOI: 10.1113/jphysiol.2002.020255 |
0.692 |
|
| 2002 |
Jones DM, Esmaeil N, Maren S, Macdonald RL. Characterization of pharmacoresistance to benzodiazepines in the rat Li-pilocarpine model of status epilepticus. Epilepsy Research. 50: 301-12. PMID 12200221 DOI: 10.1016/S0920-1211(02)00085-2 |
0.362 |
|
| 2002 |
Buhr A, Bianchi MT, Baur R, Courtet P, Pignay V, Boulenger JP, Gallati S, Hinkle DJ, Macdonald RL, Sigel E. Functional characterization of the new human GABA(A) receptor mutation beta3(R192H). Human Genetics. 111: 154-60. PMID 12189488 DOI: 10.1007/s00439-002-0766-7 |
0.824 |
|
| 2002 |
Bianchi MT, Song L, Zhang H, Macdonald RL. Two different mechanisms of disinhibition produced by GABAA receptor mutations linked to epilepsy in humans. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 5321-7. PMID 12097483 DOI: 10.1523/Jneurosci.22-13-05321.2002 |
0.717 |
|
| 2002 |
Greenfield LJ, Zaman SH, Sutherland ML, Lummis SC, Niemeyer MI, Barnard EA, Macdonald RL. Mutation of the GABAA receptor M1 transmembrane proline increases GABA affinity and reduces barbiturate enhancement. Neuropharmacology. 42: 502-21. PMID 11955521 DOI: 10.1016/S0028-3908(01)00196-4 |
0.464 |
|
| 2002 |
Wohlfarth KM, Bianchi MT, Macdonald RL. Enhanced neurosteroid potentiation of ternary GABA(A) receptors containing the delta subunit. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 1541-9. PMID 11880484 DOI: 10.1523/Jneurosci.22-05-01541.2002 |
0.704 |
|
| 2002 |
Wohlfarth KM, Bianchi MT, Macdonald RL. Enhanced Neurosteroid Potentiation of Ternary GABAAReceptors Containing the δ Subunit The Journal of Neuroscience. 22: 1541-1549. DOI: 10.1523/JNEUROSCI.22-05-01541.2002 |
0.577 |
|
| 2001 |
Macdonald RL. GABAA Receptor Defects Can Cause Epilepsy. Epilepsy Currents / American Epilepsy Society. 1: 74. PMID 15309196 DOI: 10.1046/j.1535-7597.2001.00018.x |
0.389 |
|
| 2001 |
Bianchi MT, Macdonald RL. Agonist Trapping by GABAA Receptor Channels. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 9083-91. PMID 11717341 DOI: 10.1523/Jneurosci.21-23-09083.2001 |
0.688 |
|
| 2001 |
Bianchi MT, Macdonald RL. Mutation of the 9' leucine in the GABA(A) receptor gamma2L subunit produces an apparent decrease in desensitization by stabilizing open states without altering desensitized states. Neuropharmacology. 41: 737-44. PMID 11640928 DOI: 10.1016/S0028-3908(01)00132-0 |
0.674 |
|
| 2001 |
Nagaya N, Macdonald RL. Two gamma2L subunit domains confer low Zn2+ sensitivity to ternary GABA(A) receptors. The Journal of Physiology. 532: 17-30. PMID 11283222 DOI: 10.1111/J.1469-7793.2001.0017G.X |
0.612 |
|
| 2001 |
Bianchi MT, Haas KF, Macdonald RL. Structural determinants of fast desensitization and desensitization-deactivation coupling in GABAa receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 1127-36. PMID 11160383 DOI: 10.1523/Jneurosci.21-04-01127.2001 |
0.747 |
|
| 2000 |
Neelands TR, King AP, Macdonald RL. Functional expression of L-, N-, P/Q-, and R-type calcium channels in the human NT2-N cell line. Journal of Neurophysiology. 84: 2933-44. PMID 11110822 DOI: 10.1152/Jn.2000.84.6.2933 |
0.36 |
|
| 2000 |
Fisher JL, Hinkle DJ, Macdonald RL. Loreclezole inhibition of recombinant alpha1beta1gamma2L GABA(A) receptor single channel currents. Neuropharmacology. 39: 235-45. PMID 10670419 DOI: 10.1016/S0028-3908(99)00108-2 |
0.832 |
|
| 1999 |
Burgard EC, Haas KF, Macdonald RL. Channel properties determine the transient activation kinetics of recombinant GABA(A) receptors. Brain Research. Molecular Brain Research. 73: 28-36. PMID 10581395 DOI: 10.1016/S0169-328X(99)00230-2 |
0.624 |
|
| 1999 |
MacDonald RL, Kapur J. Pharmacological properties of recombinant and hippocampal dentate granule cell GABAA receptors. Advances in Neurology. 79: 979-90. PMID 10514880 |
0.552 |
|
| 1999 |
Neelands TR, Macdonald RL. Incorporation of the π subunit into functional γ-aminobutyric acid(A) receptors Molecular Pharmacology. 56: 598-610. PMID 10462548 DOI: 10.1124/MOL.56.3.598 |
0.493 |
|
| 1999 |
Neelands TR, Zhang J, Macdonald RL. GABA(A) receptors expressed in undifferentiated human teratocarcinoma NT2 cells differ from those expressed by differentiated NT2-N cells Journal of Neuroscience. 19: 7057-7065. PMID 10436060 DOI: 10.1523/Jneurosci.19-16-07057.1999 |
0.492 |
|
| 1999 |
Macdonald RL, Kapur J. Acute cellular alterations in the hippocampus after status epilepticus. Epilepsia. 40: S9-20; discussion S2. PMID 10421557 DOI: 10.1111/J.1528-1157.1999.Tb00873.X |
0.641 |
|
| 1999 |
Kapur J, Haas KF, Macdonald RL. Physiological properties of GABAA receptors from acutely dissociated rat dentate granule cells. Journal of Neurophysiology. 81: 2464-71. PMID 10322081 DOI: 10.1152/Jn.1999.81.5.2464 |
0.735 |
|
| 1999 |
Tietz EI, Kapur J, Macdonald RL. Functional GABAA receptor heterogeneity of acutely dissociated hippocampal CA1 pyramidal cells. Journal of Neurophysiology. 81: 1575-86. PMID 10200193 DOI: 10.1152/Jn.1999.81.4.1575 |
0.642 |
|
| 1999 |
Kapur J, Macdonald RL. Postnatal development of hippocampal dentate granule cell gamma-aminobutyric acidA receptor pharmacological properties. Molecular Pharmacology. 55: 444-52. PMID 10051527 |
0.572 |
|
| 1999 |
Neelands TR, Fisher JL, Bianchi M, Macdonald RL. Spontaneous and gamma-aminobutyric acid (GABA)-activated GABA(A) receptor channels formed by epsilon subunit-containing isoforms. Molecular Pharmacology. 55: 168-78. PMID 9882711 DOI: 10.1124/Mol.55.1.168 |
0.759 |
|
| 1999 |
Haas KF, Macdonald RL. GABAA receptor subunit gamma2 and delta subtypes confer unique kinetic properties on recombinant GABAA receptor currents in mouse fibroblasts. The Journal of Physiology. 514: 27-45. PMID 9831714 DOI: 10.1111/J.1469-7793.1999.027Af.X |
0.587 |
|
| 1999 |
Coulter DA, Sloviter RS, Macdonald RL. Panel discussion: Discussion and questions from the audience Epilepsia. 40: S40-S41. DOI: 10.1111/j.1528-1157.1999.tb00877.x |
0.474 |
|
| 1999 |
Macdonald RL. Introduction and symposium overview Epilepsia. 40: S1-S2. DOI: 10.1111/J.1528-1157.1999.Tb00871.X |
0.325 |
|
| 1999 |
Haas KF, Macdonald RL. GABA(A) receptor subunit γ2 and δ subtypes confer unique kinetic properties on recombinant GABA(A) receptor currents in mouse fibroblasts Journal of Physiology. 514: 27-45. DOI: 10.1111/j.1469-7793.1999.027af.x |
0.603 |
|
| 1998 |
Fisher JL, Macdonald RL. The role of an alpha subtype M2-M3 His in regulating inhibition of GABAA receptor current by zinc and other divalent cations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 2944-53. PMID 9526011 DOI: 10.1523/Jneurosci.18-08-02944.1998 |
0.588 |
|
| 1998 |
Neelands TR, Greenfield LJ, Zhang J, Turner RS, Macdonald RL. GABAAReceptor Pharmacology and Subtype mRNA Expression in Human Neuronal NT2-N Cells The Journal of Neuroscience. 18: 4993-5007. DOI: 10.1523/JNEUROSCI.18-13-04993.1998 |
0.43 |
|
| 1997 |
Fisher JL, Macdonald RL. Functional properties of recombinant GABA(A) receptors composed of single or multiple beta subunit subtypes. Neuropharmacology. 36: 1601-10. PMID 9517431 DOI: 10.1016/S0028-3908(97)00133-0 |
0.605 |
|
| 1997 |
Fisher JL, Macdonald RL. Single channel properties of recombinant GABAA receptors containing gamma 2 or delta subtypes expressed with alpha 1 and beta 3 subtypes in mouse L929 cells. The Journal of Physiology. 505: 283-97. PMID 9423172 DOI: 10.1111/j.1469-7793.1997.283bb.x |
0.556 |
|
| 1997 |
Fisher JL, Zhang J, Macdonald RL. The role of alpha1 and alpha6 subtype amino-terminal domains in allosteric regulation of gamma-aminobutyric acida receptors. Molecular Pharmacology. 52: 714-24. PMID 9380035 DOI: 10.1124/MOL.52.4.714 |
0.595 |
|
| 1997 |
Kapur J, Macdonald RL. Rapid seizure-induced reduction of benzodiazepine and Zn2+ sensitivity of hippocampal dentate granule cell GABAA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 7532-40. PMID 9295398 DOI: 10.1523/Jneurosci.17-19-07532.1997 |
0.611 |
|
| 1997 |
Saxena NC, Neelands TR, MacDonald RL. Contrasting actions of lanthanum on different recombinant gamma-aminobutyric acid receptor isoforms expressed in L929 fibroblasts. Molecular Pharmacology. 51: 328-35. PMID 9203639 DOI: 10.1124/MOL.51.2.328 |
0.467 |
|
| 1997 |
Macdonald RL, Greenfield LJ. Mechanisms of action of new antiepileptic drugs. Current Opinion in Neurology. 10: 121-8. PMID 9147003 DOI: 10.1097/00019052-199704000-00009 |
0.377 |
|
| 1997 |
Greenfield LJ, Sun F, Neelands TR, Burgard EC, Donnelly JL, MacDonald RL. Expression of functional GABAA receptors in transfected L929 cells isolated by immunomagnetic bead separation. Neuropharmacology. 36: 63-73. PMID 9144642 DOI: 10.1016/S0028-3908(96)00150-5 |
0.397 |
|
| 1997 |
Wiley JW, Moises HC, Gross RA, MacDonald RL. Dynorphin A-mediated reduction in multiple calcium currents involves a G(o) alpha-subtype G protein in rat primary afferent neurons. Journal of Neurophysiology. 77: 1338-48. PMID 9084601 DOI: 10.1152/Jn.1997.77.3.1338 |
0.479 |
|
| 1997 |
Donnelly JL, MacDonald RL. Loreclezole enhances apparent desensitization of recombinant GABAA receptor currents. Neuropharmacology. 35: 1233-41. PMID 9014138 DOI: 10.1016/S0028-3908(96)00053-6 |
0.475 |
|
| 1996 |
Kapur J, Macdonald RL. Cyclic AMP-dependent protein kinase enhances hippocampal dentate granule cell GABAA receptor currents. Journal of Neurophysiology. 76: 2626-34. PMID 8899633 DOI: 10.1152/Jn.1996.76.4.2626 |
0.628 |
|
| 1996 |
Kapur J, Macdonald RL. Pharmacological properties of gamma-aminobutyric acidA receptors from acutely dissociated rat dentate granule cells. Molecular Pharmacology. 50: 458-66. PMID 8794882 |
0.584 |
|
| 1996 |
Macdonald RL, Kelly KM. Antiepileptic drug mechanisms of action. Epilepsia. S2-12. PMID 8784210 DOI: 10.1111/j.1528-1157.1995.tb05996.x |
0.467 |
|
| 1996 |
Greenfield LJ, Macdonald RL. Whole-cell and single-channel alpha1 beta1 gamma2S GABAA receptor currents elicited by a "multipuffer" drug application device. Pflugers Archiv : European Journal of Physiology. 432: 1080-90. PMID 8781204 DOI: 10.1007/s004240050238 |
0.392 |
|
| 1995 |
Macdonald RL. Ethanol, gamma-aminobutyrate type A receptors, and protein kinase C phosphorylation. Proceedings of the National Academy of Sciences of the United States of America. 92: 3633-5. PMID 7731956 DOI: 10.1073/PNAS.92.9.3633 |
0.315 |
|
| 1995 |
Rock DM, Macdonald RL. Polyamine regulation of N-methyl-D-aspartate receptor channels Annual Review of Pharmacology and Toxicology. 35: 463-482. PMID 7598503 DOI: 10.1146/ANNUREV.PA.35.040195.002335 |
0.393 |
|
| 1995 |
Hall K, Browning M, Dudek E, Macdonald R. Enhancement of high threshold calcium currents in rat primary afferent neurons by constitutively active protein kinase C The Journal of Neuroscience. 15: 6069-6076. DOI: 10.1523/JNEUROSCI.15-09-06069.1995 |
0.348 |
|
| 1994 |
Lin YF, Browning MD, Dudek EM, Macdonald RL. Protein kinase C enhances recombinant bovine alpha 1 beta 1 gamma 2L GABAA receptor whole-cell currents expressed in L929 fibroblasts. Neuron. 13: 1421-31. PMID 7993633 DOI: 10.1016/0896-6273(94)90427-8 |
0.477 |
|
| 1994 |
Macdonald RL, Olsen RW. GABAA receptor channels. Annual Review of Neuroscience. 17: 569-602. PMID 7516126 DOI: 10.1146/ANNUREV.NE.17.030194.003033 |
0.503 |
|
| 1994 |
Rogers CJ, Twyman RE, Macdonald RL. Benzodiazepine and beta-carboline regulation of single GABAA receptor channels of mouse spinal neurones in culture. The Journal of Physiology. 475: 69-82. PMID 7514665 DOI: 10.1113/jphysiol.1994.sp020050 |
0.485 |
|
| 1994 |
Macdonald RL, Kelly KM. Mechanisms of action of currently prescribed and newly developed antiepileptic drugs Epilepsia. 35. PMID 7513639 DOI: 10.1111/j.1528-1157.1994.tb05955.x |
0.428 |
|
| 1994 |
Saxena N, Macdonald R. Assembly of GABAA receptor subunits: role of the delta subunit The Journal of Neuroscience. 14: 7077-7086. DOI: 10.1523/JNEUROSCI.14-11-07077.1994 |
0.43 |
|
| 1994 |
Moises H, Rusin K, Macdonald R. Mu- and kappa-opioid receptors selectively reduce the same transient components of high-threshold calcium current in rat dorsal root ganglion sensory neurons The Journal of Neuroscience. 14: 5903-5916. DOI: 10.1523/JNEUROSCI.14-10-05903.1994 |
0.364 |
|
| 1994 |
Moises H, Rusin K, Macdonald R. mu-Opioid receptor-mediated reduction of neuronal calcium current occurs via a G(o)-type GTP-binding protein The Journal of Neuroscience. 14: 3842-3851. DOI: 10.1523/JNEUROSCI.14-06-03842.1994 |
0.368 |
|
| 1993 |
Wiley JW, Gross RA, MacDonald RL. Agonists for neuropeptide Y receptor subtypes NPY-1 and NPY-2 have opposite actions on rat nodose neuron calcium currents. Journal of Neurophysiology. 70: 324-30. PMID 8395583 DOI: 10.1152/Jn.1993.70.1.324 |
0.504 |
|
| 1993 |
Macdonald RL, Kelly KM. Antiepileptic drug mechanisms of action Epilepsia. 34. PMID 7687957 DOI: 10.1111/j.1528-1157.1993.tb05918.x |
0.311 |
|
| 1993 |
Angelotti TP, Uhler MD, Macdonald RL. Assembly of GABAA receptor subunits: Analysis of transient single-cell expression utilizing a fluorescent substrate/marker gene technique Journal of Neuroscience. 13: 1418-1428. PMID 7681869 DOI: 10.1523/Jneurosci.13-04-01418.1993 |
0.447 |
|
| 1993 |
Rock DM, Kelly KM, Macdonald RL. Gabapentin actions on ligand- and voltage-gated responses in cultured rodent neurons Epilepsy Research. 16: 89-98. PMID 7505742 DOI: 10.1016/0920-1211(93)90023-Z |
0.456 |
|
| 1993 |
Twyman RE, Macdonald RL. Neurosteroid regulation of GABAA receptor single-channel kinetic properties of mouse spinal cord neurons in culture. The Journal of Physiology. 456: 215-45. PMID 1338096 DOI: 10.1113/jphysiol.1992.sp019334 |
0.503 |
|
| 1993 |
Angelotti TP, Tan F, Chahine KG, Macdonald RL. Molecular and electrophysiological characterization of a allelic variant of the rat alpha 6 GABAA receptor subunit. Brain Research. Molecular Brain Research. 16: 173-8. PMID 1281255 DOI: 10.1016/0169-328X(92)90209-T |
0.413 |
|
| 1993 |
Angelotti T, Macdonald R. Assembly of GABAA receptor subunits: alpha 1 beta 1 and alpha 1 beta 1 gamma 2S subunits produce unique ion channels with dissimilar single- channel properties The Journal of Neuroscience. 13: 1429-1440. DOI: 10.1523/JNEUROSCI.13-04-01429.1993 |
0.377 |
|
| 1993 |
Macdonald RL, Angelotti TP. Native and Recombinant GABAA Receptor Channels Cellular Physiology and Biochemistry. 3: 352-373. DOI: 10.1159/000154698 |
0.382 |
|
| 1992 |
Twyman RE, Macdonald RL. Kinetic properties of the glycine receptor main- and sub-conductance states of mouse spinal cord neurones in culture. The Journal of Physiology. 435: 303-31. PMID 1722820 DOI: 10.1113/jphysiol.1991.sp018512 |
0.309 |
|
| 1992 |
Wiley JW, Gross RA, MacDonald RL. The peptide CGRP increases a high-threshold Ca2+ current in rat nodose neurones via a pertussis toxin-sensitive pathway. The Journal of Physiology. 455: 367-81. PMID 1336552 DOI: 10.1113/Jphysiol.1992.Sp019306 |
0.47 |
|
| 1992 |
Twyman RE, Green RM, MacDonald RL. Kinetics of open channel block by penicillin of single GABAA receptor channels from mouse spinal cord neurones in culture. The Journal of Physiology. 445: 97-127. PMID 1323672 DOI: 10.1113/jphysiol.1992.sp018914 |
0.479 |
|
| 1992 |
Rock DM, Macdonald RL. The polyamine diaminodecane (DA-10) produces a voltage-dependent flickery block of single NMDA receptor channels Neuroscience Letters. 144: 111-115. PMID 1279482 DOI: 10.1016/0304-3940(92)90728-P |
0.375 |
|
| 1991 |
De Deyn PP, Macdonald RL. Guanidino compounds that are increased in cerebrospinal fluid and brain of uremic patients inhibit GABA and glycine responses on mouse neurons in cell culture. Annals of Neurology. 28: 627-33. PMID 2135950 DOI: 10.1002/ANA.410280505 |
0.403 |
|
| 1991 |
Kelly KM, Gross RA, Macdonald RL. Tetrahydroaminoacridine (THA) reduces voltage-dependent calcium currents in rat sensory neurons. Neuroscience Letters. 132: 247-50. PMID 1784428 DOI: 10.1016/0304-3940(91)90312-H |
0.468 |
|
| 1991 |
De Deyn PP, Marescau B, Macdonald RL. Guanidino compounds that are increased in hyperargininemia inhibit GABA and glycine responses on mouse neurons in cell culture Epilepsy Research. 8: 134-141. PMID 1712285 DOI: 10.1016/0920-1211(91)90081-P |
0.407 |
|
| 1991 |
Rock DM, McLean MJ, Macdonald RL, Catterall WA, Taylor CP. Ralitoline (CI-946) and CI-953 block sustained repetitive sodium action potentials in cultured mouse spinal cord neurons and displace batrachotoxinin A 20-alpha-benzoate binding in vitro. Epilepsy Research. 8: 197-203. PMID 1651226 DOI: 10.1016/0920-1211(91)90064-M |
0.361 |
|
| 1991 |
Macdonald RL, Twyman RE. Biophysical properties and regulation of GABAA receptor channels Seminars in Neuroscience. 3: 219-230. DOI: 10.1016/1044-5765(91)90019-K |
0.424 |
|
| 1990 |
MacDonald RL, Rogers CJ, Twyman RE. Barbiturate regulation of kinetic properties of the GABAA receptor channel of mouse spinal neurones in culture. The Journal of Physiology. 417: 483-500. PMID 2482885 DOI: 10.1113/jphysiol.1989.sp017814 |
0.447 |
|
| 1990 |
Wiley JW, Gross RA, Lu YX, Macdonald RL. Neuropeptide Y reduces calcium current and inhibits acetylcholine release in nodose neurons via a pertussis toxin-sensitive mechanism. Journal of Neurophysiology. 63: 1499-507. PMID 2358888 DOI: 10.1152/Jn.1990.63.6.1499 |
0.493 |
|
| 1990 |
Gross RA, Uhler MD, Macdonald RL. The cyclic AMP-dependent protein kinase catalytic subunit selectively enhances calcium currents in rat nodose neurones. The Journal of Physiology. 429: 483-96. PMID 2177506 DOI: 10.1113/Jphysiol.1990.Sp018268 |
0.488 |
|
| 1990 |
Porter NM, Twyman RE, Uhler MD, Macdonald RL. Cyclic AMP-dependent protein kinase decreases GABAA receptor current in mouse spinal neurons Neuron. 5: 789-796. PMID 2176510 DOI: 10.1016/0896-6273(90)90338-G |
0.459 |
|
| 1990 |
Kelly KM, Gross RA, Macdonald RL. Valproic acid selectively reduces the low-threshold (T) calcium current in rat nodose neurons. Neuroscience Letters. 116: 233-8. PMID 2175404 DOI: 10.1016/0304-3940(90)90416-7 |
0.477 |
|
| 1990 |
Moss SJ, Smart TG, Porter NM, Nayeem N, Devine J, Stephenson FA, Macdonald RL, Barnard EA. Cloned GABA receptors are maintained in a stable cell line: allosteric and channel properties. European Journal of Pharmacology. 189: 77-88. PMID 2171964 DOI: 10.1016/0922-4106(90)90232-M |
0.514 |
|
| 1990 |
Twyman RE, Rogers CJ, Macdonald RL. Intraburst kinetic properties of the GABAA receptor main conductance state of mouse spinal cord neurones in culture. The Journal of Physiology. 423: 193-220. PMID 2167362 DOI: 10.1113/jphysiol.1990.sp018018 |
0.426 |
|
| 1990 |
Gross RA, Wiley JW, Ryan-Jastrow T, Macdonald RL. Regulation by GTP and its stable thiol derivatives of calcium current components in rat nodose ganglion neurons. Molecular Pharmacology. 37: 546-53. PMID 2157961 |
0.424 |
|
| 1990 |
Gross RA, Moises HC, Uhler MD, Macdonald RL. Dynorphin A and cAMP-dependent protein kinase independently regulate neuronal calcium currents. Proceedings of the National Academy of Sciences of the United States of America. 87: 7025-9. PMID 1976250 DOI: 10.1073/Pnas.87.18.7025 |
0.489 |
|
| 1990 |
Gross RA, Uhler MD, Macdonald RL. The reduction of neuronal calcium currents by ATP-gamma-S is mediated by a G protein and occurs independently of cyclic AMP-dependent protein kinase. Brain Research. 535: 214-20. PMID 1963568 DOI: 10.1016/0006-8993(90)91603-E |
0.499 |
|
| 1990 |
Wiley J, Gross R, Macdonald R. Calcitonin gene-related peptide (CGRP) and protein kinase a (PKA) increase the N-type calcium current in rat vagal sensory (Nodose) neurons Gastroenterology. 99: 1236. DOI: 10.1016/0016-5085(90)90803-9 |
0.341 |
|
| 1989 |
Deyn PPD, Macdonald RL. Effects of antiepileptic drugs on GABA responses and on reduction of GABA responses by PTZ and DMCM on mouse neurons in cell culture. Epilepsia. 30: 17-25. PMID 2912714 DOI: 10.1111/J.1528-1157.1989.Tb05275.X |
0.388 |
|
| 1989 |
Gross RA, MacDonald RL. Activators of protein kinase C selectively enhance inactivation of a calcium current component of cultured sensory neurons in a pertussis toxin-sensitive manner. Journal of Neurophysiology. 61: 1259-69. PMID 2746325 DOI: 10.1152/Jn.1989.61.6.1259 |
0.48 |
|
| 1989 |
Gross RA, Macdonald RL, Ryan-Jastrow T. 2-Chloroadenosine reduces the N calcium current of cultured mouse sensory neurones in a pertussis toxin-sensitive manner. The Journal of Physiology. 411: 585-95. PMID 2614735 DOI: 10.1113/Jphysiol.1989.Sp017592 |
0.476 |
|
| 1989 |
Rock DM, Macdonald RL, Taylor CP. Blockade of sustained repetitive action potentials in cultured spinal cord neurons by zonisamide (AD 810, CI 912), a novel anticonvulsant. Epilepsy Research. 3: 138-43. PMID 2565229 DOI: 10.1016/0920-1211(89)90041-7 |
0.393 |
|
| 1989 |
Macdonald RL. Antiepileptic drug actions. Epilepsia. S19-28; discussion S. PMID 2550216 DOI: 10.1111/j.1528-1157.1989.tb05810.x |
0.474 |
|
| 1989 |
Gross RA, Macdonald RL. Cyclic AMP selectively reduces the N-type calcium current component of mouse sensory neurons in culture by enhancing inactivation. Journal of Neurophysiology. 61: 97-105. PMID 2537387 DOI: 10.1152/Jn.1989.61.1.97 |
0.466 |
|
| 1989 |
Macdonald RL, Rogers CJ, Twyman RE. Kinetic properties of the GABAA receptor main conductance state of mouse spinal cord neurones in culture. The Journal of Physiology. 410: 479-99. PMID 2477526 DOI: 10.1113/jphysiol.1989.sp017545 |
0.412 |
|
| 1989 |
Twyman RE, Rogers CJ, Macdonald RL. Differential regulation of gamma-aminobutyric acid receptor channels by diazepam and phenobarbital. Annals of Neurology. 25: 213-20. PMID 2471436 DOI: 10.1002/ANA.410250302 |
0.502 |
|
| 1989 |
Twyman RE, Rogers CJ, Macdonald RL. Pentobarbital and picrotoxin have reciprocal actions on single GABAA receptor channels. Neuroscience Letters. 96: 89-95. PMID 2467232 DOI: 10.1016/0304-3940(89)90248-6 |
0.499 |
|
| 1988 |
De Deyn PP, Marescau B, Macdonald RL. Effects of α-keto-δ-guanidinovaleric acid on inhibitory amino acid responses on mouse neurons in cell culture Brain Research. 449: 54-60. PMID 3395858 DOI: 10.1016/0006-8993(88)91023-2 |
0.409 |
|
| 1988 |
Macdonald RL. Anticonvulsant drug actions on neurons in cell culture Journal of Neural Transmission. 72: 173-183. PMID 3047314 DOI: 10.1007/Bf01243417 |
0.357 |
|
| 1988 |
Deyn PPD, Macdonald RL. Effects of non-sedative anxiolytic drugs on responses to GABA and on diazepam-induced enhancement of these responses on mouse neurones in cell culture. British Journal of Pharmacology. 95: 109-120. PMID 2905900 DOI: 10.1111/J.1476-5381.1988.Tb16554.X |
0.442 |
|
| 1988 |
Gross RA, Macdonald RL. Differential actions of pentobarbitone on calcium current components of mouse sensory neurones in culture. The Journal of Physiology. 405: 187-203. PMID 2855640 DOI: 10.1113/Jphysiol.1988.Sp017328 |
0.477 |
|
| 1988 |
Gross RA, Macdonald RL. Reduction of the same calcium current component by A and C kinases: differential pertussis toxin sensitivity. Neuroscience Letters. 88: 50-6. PMID 2456492 DOI: 10.1016/0304-3940(88)90314-X |
0.452 |
|
| 1988 |
Gross RA, Macdonald RL. Barbiturates and nifedipine have different and selective effects on calcium currents of mouse DRG neurons in culture: a possible basis for differing clinical actions. The 1987 S. Weir Mitchell award. Neurology. 38: 443-51. PMID 2450304 DOI: 10.1212/Wnl.38.3.443 |
0.48 |
|
| 1987 |
Werz MA, Macdonald RL. Dual actions of phorbol esters to decrease calcium and potassium conductances of mouse neurons. Neuroscience Letters. 78: 101-6. PMID 2441331 DOI: 10.1016/0304-3940(87)90569-6 |
0.322 |
|
| 1987 |
Gross RA, Macdonald RL. Dynorphin A selectively reduces a large transient (N-type) calcium current of mouse dorsal root ganglion neurons in cell culture. Proceedings of the National Academy of Sciences of the United States of America. 84: 5469-73. PMID 2440050 DOI: 10.1073/Pnas.84.15.5469 |
0.492 |
|
| 1987 |
Grega DS, Werz MA, Macdonald RL. Forskolin and phorbol esters reduce the same potassium conductance of mouse neurons in culture. Science (New York, N.Y.). 235: 345-8. PMID 2432663 DOI: 10.1126/SCIENCE.2432663 |
0.327 |
|
| 1987 |
Macdonald RL, Werz MA. Dynorphin A decreases voltage-dependent calcium conductance of mouse dorsal root ganglion neurones. The Journal of Physiology. 377: 237-49. PMID 2432242 DOI: 10.1113/jphysiol.1986.sp016184 |
0.349 |
|
| 1987 |
Werz M, Macdonald R. Phorbol esters: voltage-dependent effects on calcium-dependent action potentials of mouse central and peripheral neurons in cell culture The Journal of Neuroscience. 7: 1639-1647. DOI: 10.1523/JNEUROSCI.07-06-01639.1987 |
0.346 |
|
| 1987 |
Grega D, Macdonald R. Activators of adenylate cyclase and cyclic AMP prolong calcium- dependent action potentials of mouse sensory neurons in culture by reducing a voltage-dependent potassium conductance The Journal of Neuroscience. 7: 700-707. DOI: 10.1523/JNEUROSCI.07-03-00700.1987 |
0.323 |
|
| 1986 |
Macdonald RL, Weddle MG, Gross RA. Benzodiazepine, beta-carboline, and barbiturate actions on GABA responses. Advances in Biochemical Psychopharmacology. 41: 67-78. PMID 2874695 |
0.434 |
|
| 1986 |
MacDonald RL, Skerritt JH, Werz MA. Adenosine agonists reduce voltage-dependent calcium conductance of mouse sensory neurones in cell culture. The Journal of Physiology. 370: 75-90. PMID 2420981 DOI: 10.1113/jphysiol.1986.sp015923 |
0.371 |
|
| 1985 |
Werz MA, Macdonald RL. Dynorphin reduces voltage-dependent calcium conductance of mouse dorsal root ganglion neurons. Neuropeptides. 5: 253-6. PMID 6152324 DOI: 10.1016/0143-4179(84)90075-1 |
0.364 |
|
| 1985 |
Skerritt JH, Johnston GA, Chow SC, MacDonald RL, Prager RH, Ward AD. Differential modulation of gamma-aminobutyric acid receptors by caprolactam derivatives with central nervous system depressant or convulsant activity. Brain Research. 331: 225-33. PMID 2985202 DOI: 10.1016/0006-8993(85)91548-3 |
0.424 |
|
| 1984 |
Skerritt JH, Macdonald RL. Diazepam enhances the action but not the binding of the GABA analog, THIP. Brain Research. 297: 181-6. PMID 6722533 DOI: 10.1016/0006-8993(84)90557-2 |
0.413 |
|
| 1984 |
Skerritt JH, Werz MA, McLean MJ, Macdonald RL. Diazepam and its anomalous p-chloro-derivative Ro 5-4864: comparative effects on mouse neurons in cell culture. Brain Research. 310: 99-105. PMID 6478244 DOI: 10.1016/0006-8993(84)90013-1 |
0.332 |
|
| 1984 |
Werz MA, MacDonald RL. Opioid peptides selective for mu- and delta-opiate receptors reduce calcium-dependent action potential duration by increasing potassium conductance. Neuroscience Letters. 42: 173-8. PMID 6320066 DOI: 10.1016/0304-3940(83)90402-0 |
0.347 |
|
| 1984 |
Werz MA, Macdonald RL. Dynorphin reduces calcium-dependent action potential duration by decreasing voltage-dependent calcium conductance. Neuroscience Letters. 46: 185-90. PMID 6146120 DOI: 10.1016/0304-3940(84)90439-7 |
0.377 |
|
| 1984 |
Skerritt JH, Macdonald RL. Benzodiazepine Ro 15-1788: electrophysiological evidence for partial agonist activity. Neuroscience Letters. 43: 321-6. PMID 6143288 DOI: 10.1016/0304-3940(83)90208-2 |
0.432 |
|
| 1984 |
Skerritt JH, Macdonald RL. Benzodiazepine receptor ligand actions on GABA responses. Beta-carbolines, purines. European Journal of Pharmacology. 101: 135-41. PMID 6086358 DOI: 10.1016/0014-2999(84)90039-6 |
0.424 |
|
| 1984 |
Skerritt JH, Macdonald RL. Benzodiazepine receptor ligand actions on GABA responses. Benzodiazepines, CL 218872, zopiclone. European Journal of Pharmacology. 101: 127-34. PMID 6086357 DOI: 10.1016/0014-2999(84)90038-4 |
0.44 |
|
| 1984 |
Macdonald RL, Skerritt JH, McLean MJ. Anticonvulsant drug actions on GABA responses and sustained repetitive firing of neurons in cell culture Neuropharmacology. 23: 843-844. DOI: 10.1016/0028-3908(84)90275-2 |
0.438 |
|
| 1983 |
Nelson PG, Marshall KC, Pun RY, Christian CN, Sheriff WH, Macdonald RL, Neale EA. Synaptic interactions between mammalian central neurons in cell culture. II. Quantal Analysis of EPSPs. Journal of Neurophysiology. 49: 1442-58. PMID 6875632 DOI: 10.1152/Jn.1983.49.6.1442 |
0.514 |
|
| 1983 |
Macdonald RL, Pun RY, Neale EA, Nelson PG. Synaptic interactions between mammalian central neurons in cell culture. I. Reversal potential for excitatory postsynaptic potentials. Journal of Neurophysiology. 49: 1428-41. PMID 6875631 DOI: 10.1152/Jn.1983.49.6.1428 |
0.54 |
|
| 1983 |
Nowak LM, Macdonald RL. Muscarine-sensitive voltage-dependent potassium current in cultured murine spinal cord neurons. Neuroscience Letters. 35: 85-91. PMID 6843894 DOI: 10.1016/0304-3940(83)90531-1 |
0.716 |
|
| 1983 |
Nowak LM, Macdonald RL. Ionic mechanism of muscarinic cholinergic depolarization of mouse spinal cord neurons in cell culture. Journal of Neurophysiology. 49: 792-803. PMID 6834099 DOI: 10.1152/Jn.1983.49.3.792 |
0.751 |
|
| 1983 |
Bergey GK, MacDonald RL, Habig WH, Hardegree MC, Nelson PG. Tetanus toxin: convulsant action on mouse spinal cord neurons in culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 3: 2310-23. PMID 6631482 DOI: 10.1523/Jneurosci.03-11-02310.1983 |
0.578 |
|
| 1983 |
Neale EA, Nelson PG, Macdonald RL, Christian CN, Bowers LM. Synaptic interactions between mammalian central neurons in cell culture. III. Morphophysiological correlates of quantal synaptic transmission. Journal of Neurophysiology. 49: 1459-68. PMID 6308178 |
0.46 |
|
| 1982 |
Neale EA, Moonen G, Macdonald RL, Nelson PG. Cerebellar macroneurons in microexplant cell culture: ultrastructural morphology. Neuroscience. 7: 1879-90. PMID 7133404 DOI: 10.1016/0306-4522(82)90004-5 |
0.527 |
|
| 1982 |
Werz MA, Macdonald RL. Opioid peptides decrease calcium-dependent action potential duration of mouse dorsal root ganglion neurons in cell culture. Brain Research. 239: 315-21. PMID 7093688 DOI: 10.1016/0006-8993(82)90859-9 |
0.35 |
|
| 1982 |
Werz MA, Macdonald RL. Opiate alkaloids antagonize postsynaptic glycine and GABA responses: correlation with convulsant action. Brain Research. 236: 107-19. PMID 7066678 DOI: 10.1016/0006-8993(82)90038-5 |
0.402 |
|
| 1982 |
Heyer EJ, Nowak LM, Macdonald RL. Membrane depolarization and prolongation of calcium-dependent action potentials of mouse neurons in cell culture by two convulsants: bicuculline and penicillin. Brain Research. 232: 41-56. PMID 7055710 DOI: 10.1016/0006-8993(82)90609-6 |
0.724 |
|
| 1982 |
Moonen G, Neale EA, Macdonald RL, Gibbs W, Nelson PG. Cerebellar macroneurons in microexplant cell culture. Methodology, basic electrophysiology, and morphology after horseradish peroxidase injection. Brain Research. 281: 59-73. PMID 6291726 DOI: 10.1016/0165-3806(82)90113-4 |
0.537 |
|
| 1982 |
Werz MA, Macdonald RL. Heterogeneous sensitivity of cultured dorsal root ganglion neurones to opioid peptides selective for mu- and delta-opiate receptors. Nature. 299: 730-3. PMID 6289131 DOI: 10.1038/299730A0 |
0.408 |
|
| 1982 |
Nowak LM, Young AB, Macdonald RL. GABA and bicuculline actions on mouse spinal cord and cortical neurons in cell culture. Brain Research. 244: 155-64. PMID 6288177 DOI: 10.1016/0006-8993(82)90913-1 |
0.76 |
|
| 1982 |
Frere RC, Macdonald RL, Young AB. GABA binding and bicuculline in spinal cord and cortical membranes from adult rat and from mouse neurons in cell culture. Brain Research. 244: 145-53. PMID 6288176 DOI: 10.1016/0006-8993(82)90912-X |
0.366 |
|
| 1982 |
Heyer EJ, Macdonald RL. Barbiturate reduction of calcium-dependent action potentials: correlation with anesthetic action. Brain Research. 236: 157-71. PMID 6279233 DOI: 10.1016/0006-8993(82)90042-7 |
0.37 |
|
| 1982 |
Nowak LM, Macdonald RL. Substance P: ionic basis for depolarizing responses of mouse spinal cord neurons in cell culture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 2: 1119-28. PMID 6180151 DOI: 10.1523/Jneurosci.02-08-01119.1982 |
0.703 |
|
| 1982 |
Macdonald RL, Moonen G, Neale EA, Nelson PG. Cerebellar macroneurons in microexplant cell culture. Postsynaptic amino acid pharmacology. Brain Research. 281: 75-88. PMID 6128065 DOI: 10.1016/0165-3806(82)90114-6 |
0.588 |
|
| 1981 |
Heyer EJ, MacDonald RL, Bergey GK, Nelson PG. Calcium-dependent action potentials in mouse spinal cord neurons in cell culture. Brain Research. 220: 408-15. PMID 7284766 DOI: 10.1016/0006-8993(81)91234-8 |
0.533 |
|
| 1981 |
Heyer EJ, Nowak LM, Macdonald RL. Bicuculline: a convulsant with synaptic and nonsynaptic actions. Neurology. 31: 1381-90. PMID 7198187 DOI: 10.1212/Wnl.31.11.1381 |
0.732 |
|
| 1981 |
Macdonald RL, Young AB. Pharmacology of GABA-mediated inhibition of spinal cord neurons in vivo and in primary dissociated cell culture. Molecular and Cellular Biochemistry. 38: 147-62. PMID 6270545 DOI: 10.1007/BF00235693 |
0.443 |
|
| 1981 |
Schulz DW, Macdonald RL. Barbiturate enhancement of GABA-mediated inhibition and activation of chloride ion conductance: correlation with anticonvulsant and anesthetic actions. Brain Research. 209: 177-88. PMID 6260300 DOI: 10.1016/0006-8993(81)91179-3 |
0.449 |
|
| 1981 |
Nowak LM, MacDonald RL. Substance P decreases a potassium conductance of spinal cord neurons in cell culture. Brain Research. 214: 416-23. PMID 6165445 DOI: 10.1016/0006-8993(81)91205-1 |
0.694 |
|
| 1981 |
Macdonald RL, Nowak LM. Substance P and somatostatin actions on spinal cord neurons in primary dissociated cell culture. Advances in Biochemical Psychopharmacology. 28: 159-73. PMID 6163331 |
0.679 |
|
| 1980 |
Neale EA, MacDonald RL, Nelson PG. An inhibitory spinal cord neuron. Jama. 244: 2555. PMID 7431596 DOI: 10.1001/jama.1980.03310220053031 |
0.501 |
|
| 1980 |
Macdonald RL, Nowak LM. Somatostatin actions in primary dissociated cell cultures of mammalian spinal cord neurons. International Journal of Neurology. 14: 221-32. PMID 6152909 |
0.662 |
|
| 1979 |
MacDonald RL, Barker JL. Enhancement of GABA-mediated postsynaptic inhibition in cultured mammalian spinal cord neurons: a common mode of anticonvulsant action. Brain Research. 167: 323-36. PMID 445132 DOI: 10.1016/0006-8993(79)90826-6 |
0.433 |
|
| 1979 |
Macdonald RL, Bergey GK. Valproic acid augments GABA-mediated postsynaptic inhibition in cultured mammalian neurons. Brain Research. 170: 558-62. PMID 380778 DOI: 10.1016/0006-8993(79)90975-2 |
0.391 |
|
| 1979 |
Macdonald RL, Barker JL. Anticonvulsant and anesthetic barbiturates: different postsynaptic actions in cultured mammalian neurons. Neurology. 29: 432-47. PMID 220560 DOI: 10.1212/WNL.29.4.432 |
0.449 |
|
| 1978 |
Nelson PG, Neale EA, Macdonald RL. Formation and modification of synapses in central nervous system cell cultures. Federation Proceedings. 37: 2010-5. PMID 565301 |
0.426 |
|
| 1978 |
Macdonald RL, Barker JL. Specific antagonism of GABA-mediated postsynaptic inhibition in cultured mammalian spinal cord neurons: a common mode of convulsant action. Neurology. 28: 325-30. PMID 565020 DOI: 10.1212/WNL.28.4.325 |
0.409 |
|
| 1978 |
Macdonald R, Barker JL. Benzodiazepines specifically modulate GABA-mediated postsynaptic inhibition in cultured mammalian neurones. Nature. 271: 563-4. PMID 563985 DOI: 10.1038/271563A0 |
0.475 |
|
| 1978 |
Neale EA, Macdonald RL, Nelson PG. Intracellular horseradish peroxidase injection for correlation of light and electron microscopic anatomy with synaptic physiology of cultured mouse spinal cord neurons. Brain Research. 152: 265-82. PMID 209872 DOI: 10.1016/0006-8993(78)90255-X |
0.532 |
|
| 1978 |
Macdonald RL, Barker JL. Different actions of anticonvulsant and anesthetic barbiturates revealed by use of cultured mammalian neurons. Science (New York, N.Y.). 200: 775-7. PMID 205953 DOI: 10.1126/SCIENCE.205953 |
0.431 |
|
| 1978 |
Macdonald RL, Nelson PG. Specific-opiate-induced depression of transmitter release from dorsal root ganglion cells in culture. Science (New York, N.Y.). 199: 1449-51. PMID 204015 DOI: 10.1126/Science.204015 |
0.518 |
|
| 1977 |
Macdonald RL, Barker JL. Pentylenetetrazol and penicillin are selective antagonists of GABA-mediated post-synaptic inhibition in cultured mammalian neurones. Nature. 267: 720-1. PMID 195224 DOI: 10.1038/267720A0 |
0.414 |
|
| 1976 |
Cohen DH, MacDonald RL. Involvement of the avian hypothalamus in defensively conditioned heart rate change. The Journal of Comparative Neurology. 167: 465-80. PMID 1270630 DOI: 10.1002/Cne.901670405 |
0.39 |
|
| 1973 |
Macdonald RL, Cohen DH. Heart rate and blood pressure responses to electrical stimulation of the central nervous system in the pigeon (Columba livia). The Journal of Comparative Neurology. 150: 109-36. PMID 4579121 DOI: 10.1002/Cne.901500202 |
0.4 |
|
| 1971 |
Cohen DH, Macdonald RL. Some variables affecting orienting and conditioned heart-rate responses in the pigeon. Journal of Comparative and Physiological Psychology. 74: 123-33. PMID 5163697 DOI: 10.1037/H0030326 |
0.369 |
|
| 1970 |
Macdonald RL, Cohen DH. Cells of origin of sympathetic pre- and postganglionic cardioacceleratory fibers in the pigeon. The Journal of Comparative Neurology. 140: 343-58. PMID 5476888 DOI: 10.1002/Cne.901400307 |
0.395 |
|
| 1970 |
Cohen DH, Schnall AM, Macdonald RL, Pitts LH. Medullary cells of origin of vagal cardioinhibitory fibers in the pigeon. I. Anatomical studies of peripheral vagus nerve and the dorsal motor nucleus. The Journal of Comparative Neurology. 140: 299-320. PMID 5476886 DOI: 10.1002/Cne.901400305 |
0.396 |
|
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