| Year |
Citation |
Score |
| 2023 |
Li B, Qi F, Zhu F, Lu Z, Wang M, Chu T, Wu S, Wei J, Song Z, Sukumar S, Zhang C, Xu J, Li S, Nie G. Nanoparticle-based combination therapy enhances fulvestrant efficacy and overcomes tumor resistance in ER-positive breast cancer. Cancer Research. PMID 37326467 DOI: 10.1158/0008-5472.CAN-22-3559 |
0.361 |
|
| 2022 |
Visvanathan K, Cope L, Fackler MJ, Considine M, Sokoll L, Carey LA, Forero-Torres A, Ingle JN, Lin NU, Nanda R, Storniolo AM, Tulac S, Venkatesan N, Wu NC, Marla S, ... ... Sukumar S, et al. Evaluation of a Liquid Biopsy-Breast Cancer Methylation (LBx-BCM) Cartridge Assay for Predicting Early Disease Progression and Survival: TBCRC 005 Prospective Trial. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 36534524 DOI: 10.1158/1078-0432.CCR-22-2128 |
0.427 |
|
| 2022 |
Pai P, Wang G, Teo WW, Raez-Rodriguez D, Gabrielson KL, Győrffy B, Downs BM, Aggarwal A, Sukumar S. HOXA5-Mediated Stabilization of IκBα Inhibits the NF-κB Pathway and Suppresses Malignant Transformation of Breast Epithelial Cells. Cancer Research. OF1-OF13. PMID 36166646 DOI: 10.1158/0008-5472.CAN-21-4277 |
0.475 |
|
| 2022 |
Fackler MJ, Tulac S, Venkatesan N, Aslam AJ, de Guzman TN, Mercado-Rodriguez C, Cope LM, Downs BM, Vali AH, Ding W, Lehman J, Denbow R, Reynolds J, Buckley ME, Visvanathan K, ... ... Sukumar S, et al. Development of an automated liquid biopsy assay for methylated markers in advanced breast cancer. Cancer Research Communications. 2: 391-401. PMID 36046124 DOI: 10.1158/2767-9764.crc-22-0133 |
0.374 |
|
| 2022 |
Liu J, Guo L, Rao Y, Zheng W, Gao D, Zhang J, Luo L, Kuang X, Sukumar S, Tu Y, Chen C, Sun S. In situ Injection of pH- and Temperature-Sensitive Nanomaterials Increases Chemo-Photothermal Efficacy by Alleviating the Tumor Immunosuppressive Microenvironment. International Journal of Nanomedicine. 17: 2661-2678. PMID 35733417 DOI: 10.2147/IJN.S367121 |
0.371 |
|
| 2022 |
Wang G, Kumar A, Ding W, Korangath P, Bera T, Wei J, Pai P, Gabrielson K, Pastan I, Sukumar S. Intraductal administration of transferrin receptor-targeted immunotoxin clears ductal carcinoma in situ in mouse models of breast cancer-a preclinical study. Proceedings of the National Academy of Sciences of the United States of America. 119: e2200200119. PMID 35675429 DOI: 10.1073/pnas.2200200119 |
0.382 |
|
| 2022 |
Smith YE, Wang G, Flynn CL, Madden SF, MacEneaney O, Cruz RGB, Richards CE, Jahns H, Brennan M, Cremona M, Hennessy BT, Sheehan K, Casucci A, Sani FA, Hudson L, ... ... Sukumar S, et al. Functional Antagonism of Junctional Adhesion Molecule-A (JAM-A), Overexpressed in Breast Ductal Carcinoma In Situ (DCIS), Reduces HER2-Positive Tumor Progression. Cancers. 14. PMID 35267611 DOI: 10.3390/cancers14051303 |
0.452 |
|
| 2021 |
Yan Y, Narayan A, Cho S, Cheng Z, Liu JO, Zhu H, Wang G, Wharram B, Lisok A, Brummet M, Saeki H, Huang T, Gabrielson K, Gabrielson E, Cope L, ... ... Sukumar S, et al. CRYβB2 enhances tumorigenesis through upregulation of nucleolin in triple negative breast cancer. Oncogene. PMID 34341513 DOI: 10.1038/s41388-021-01975-3 |
0.535 |
|
| 2021 |
Li J, Downs BM, Cope LM, Fackler MJ, Zhang X, Song CG, VandenBussche C, Zhang K, Han Y, Liu Y, Tulac S, Venkatesan N, de Guzman T, Chen C, Lai EW, ... ... Sukumar S, et al. Automated and rapid detection of cancer in suspicious axillary lymph nodes in patients with breast cancer. Npj Breast Cancer. 7: 89. PMID 34234148 DOI: 10.1038/s41523-021-00298-6 |
0.306 |
|
| 2021 |
Gao D, Liu J, Yuan J, Wu J, Kuang X, Kong D, Zheng W, Wang G, Sukumar S, Tu Y, Chen C, Sun S. Intraductal administration of N-methyl-N-nitrosourea as a novel rodent mammary tumor model. Annals of Translational Medicine. 9: 576. PMID 33987274 DOI: 10.21037/atm-21-1540 |
0.311 |
|
| 2020 |
Han L, Korangath P, Nguyen NK, Diehl A, Cho S, Teo WW, Cope L, Gessler M, Romer L, Sukumar S. HEYL Regulates Neoangiogenesis Through Overexpression in Both Breast Tumor Epithelium and Endothelium. Frontiers in Oncology. 10: 581459. PMID 33520697 DOI: 10.3389/fonc.2020.581459 |
0.406 |
|
| 2020 |
Fackler MJ, Cho S, Cope L, Gabrielson E, Visvanathan K, Wilsbach K, Meir-Levi D, Lynch CF, Marks J, Geradts J, Regan MM, Viale G, Wolff AC, Sukumar S, Umbricht CB. DNA methylation markers predict recurrence-free interval in triple-negative breast cancer. Npj Breast Cancer. 6: 3. PMID 33514703 DOI: 10.1038/s41523-020-0145-3 |
0.33 |
|
| 2020 |
Avraham A, Feldman S, Cho SS, Kol A, Heler L, Riklin-Nahmias E, Sella A, Karni T, Allweis TM, Sukumar S, Evron E. Breast-Specific Epigenetic Regulation of DeltaNp73 and Its Role in DNA-Damage-Response of -Mutated Human Mammary Epithelial Cells. Cancers. 12. PMID 32825620 DOI: 10.3390/Cancers12092367 |
0.562 |
|
| 2020 |
Kuang XW, Liu JH, Sun ZH, Sukumar S, Sun SR, Chen C. Intraductal Therapy in Breast Cancer: Current Status and Future Prospective. Journal of Mammary Gland Biology and Neoplasia. PMID 32577880 DOI: 10.1007/S10911-020-09453-4 |
0.489 |
|
| 2020 |
Jonkers J, Pai P, Sukumar S. Multiple roles of HOX proteins in Metastasis: Let me count the ways. Cancer Metastasis Reviews. PMID 32572656 DOI: 10.1007/S10555-020-09908-4 |
0.448 |
|
| 2020 |
Korangath P, Barnett JD, Sharma A, Henderson ET, Stewart J, Yu SH, Kandala SK, Yang CT, Caserto JS, Hedayati M, Armstrong TD, Jaffee E, Gruettner C, Zhou XC, Fu W, ... ... Sukumar S, et al. Nanoparticle interactions with immune cells dominate tumor retention and induce T cell-mediated tumor suppression in models of breast cancer. Science Advances. 6: eaay1601. PMID 32232146 DOI: 10.1126/Sciadv.Aay1601 |
0.408 |
|
| 2020 |
Gilpatrick T, Lee I, Graham JE, Raimondeau E, Bowen R, Heron A, Downs B, Sukumar S, Sedlazeck FJ, Timp W. Targeted nanopore sequencing with Cas9-guided adapter ligation. Nature Biotechnology. PMID 32042167 DOI: 10.1038/S41587-020-0407-5 |
0.321 |
|
| 2020 |
Fackler MJ, Cho S, Cope L, Gabrielson E, Visvanathan K, Wilsbach K, Meir-Levi D, Lynch CF, Marks J, Geradts J, Regan MM, Viale G, Wolff AC, Sukumar S, Umbricht CB. DNA methylation markers predict recurrence-free interval in triple-negative breast cancer. Npj Breast Cancer. 6: 3. PMID 32025567 DOI: 10.1038/s41523-020-0145-3 |
0.325 |
|
| 2020 |
Li J, Downs B, Cope L, Zhang X, Song C, Zhang K, Han Y, Fackler MJ, Lai E, Tulac S, Venkatesan N, Guzman T, Chen C, Yuan J, Sukumar S. Abstract P4-02-06: Automated molecular diagnosis of suspicious axillary lymph nodes in breast cancer patients Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P4-02-06 |
0.516 |
|
| 2020 |
Hopkins AM, Smith YE, Wang G, Flynn C, Casucci A, Vellanki SH, Hudson L, Brennan K, Cremona M, Sukumar S. Abstract P3-06-01: Junctional adhesion molecule-A (JAM-A) as a novel future drug target in ductal carcinoma in situ (DCIS) Cancer Research. 80. DOI: 10.1158/1538-7445.Sabcs19-P3-06-01 |
0.508 |
|
| 2020 |
Wang G, Sukumar S. Characteristics and antitumor activity of polysorbate 80 curcumin micelles preparation by cloud point cooling Journal of Drug Delivery Science and Technology. 59: 101871. DOI: 10.1016/J.Jddst.2020.101871 |
0.384 |
|
| 2019 |
Liu JO, Guo Z, Cheng Z, Wang J, Liu W, Peng H, Wang Y, Rao S, Li R, Ying X, Korangath P, Liberti M, Li Y, Xie Y, Hong S, ... ... Sukumar S, et al. Discovery of a potent GLUT inhibitor using rapafucin 3D microarrays. Angewandte Chemie (International Ed. in English). PMID 31591797 DOI: 10.1002/Anie.201905578 |
0.363 |
|
| 2019 |
Ding L, Su Y, Fassl A, Hinohara K, Qiu X, Harper NW, Huh SJ, Bloushtain-Qimron N, Jovanović B, Ekram M, Zi X, Hines WC, Alečković M, Gil Del Alcazar C, Caulfield RJ, ... ... Sukumar S, et al. Perturbed myoepithelial cell differentiation in BRCA mutation carriers and in ductal carcinoma in situ. Nature Communications. 10: 4182. PMID 31519911 DOI: 10.1038/S41467-019-12125-5 |
0.539 |
|
| 2019 |
Downs B, Mercado-Rodriguez C, Cimino-Mathews A, Chen C, Yuan J, Van Den Berg EJ, Cope L, Schmitt F, Tse GM, Ali SZ, Meir-Levi D, Sood R, Li J, Richardson AL, Mosunjac M, ... ... Sukumar S, et al. DNA Methylation Markers for Breast Cancer Detection in the Developing World. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31300453 DOI: 10.1158/1078-0432.Ccr-18-3277 |
0.552 |
|
| 2019 |
Wang G, Chen C, Pai P, Korangath P, Sun S, Merino VF, Yuan J, Li S, Nie G, Stearns V, Sukumar S. Intraductal fulvestrant for Therapy of ERα-positive Ductal Carcinoma in Situ (DCIS) of the breast- a Preclinical Study. Carcinogenesis. PMID 31046118 DOI: 10.1093/Carcin/Bgz084 |
0.579 |
|
| 2019 |
Wolf MT, Ganguly S, Wang TL, Anderson CW, Sadtler K, Narain R, Cherry C, Parrillo AJ, Park BV, Wang G, Pan F, Sukumar S, Pardoll DM, Elisseeff JH. A biologic scaffold-associated type 2 immune microenvironment inhibits tumor formation and synergizes with checkpoint immunotherapy. Science Translational Medicine. 11. PMID 30700576 DOI: 10.1126/Scitranslmed.Aat7973 |
0.316 |
|
| 2019 |
Downs B, Cope L, Fackler M, Cho S, Wolff A, Regan M, Sukumar S, Umbricht C. Abstract P5-12-04: A new method of data analysis to derive DNA methylation signatures that stratify risk of recurrence in triple negative breast cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-P5-12-04 |
0.486 |
|
| 2019 |
Fackler M, Cho S, Cope L, Gabrielson E, Wilsbach K, Lynch C, Marks J, Geradts J, Regan M, Viale G, Wolff A, Umbricht C, Sukumar S. Abstract P4-08-09: DNA methylation markers predict recurrence-free interval in triple-negative breast cancer Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-P4-08-09 |
0.496 |
|
| 2019 |
Pai P, Wang G, Rodríguez DR, Yu W, Sukumar S. Abstract 3475: Suppression of inflammatory signaling by HOXA5 via modulation of the NF-KB pathway in breast cancer Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-3475 |
0.457 |
|
| 2019 |
Godet I, Shin YJ, Ju JA, Bhoyar S, Ye IC, Wang G, Sukumar S, Gilkes DM. Abstract 2649: A novel approach to fate-map hypoxic cells during tumor progression uncovers metastatic potency of post-hypoxic cells Cancer Research. 79: 2649-2649. DOI: 10.1158/1538-7445.Am2019-2649 |
0.479 |
|
| 2018 |
Merino VF, Cho S, Nguyen N, Sadik H, Narayan A, Talbot C, Cope L, Zhou XC, Zhang Z, Győrffy B, Sukumar S. Induction of cell cycle arrest and inflammatory genes by combined treatment with epigenetic, differentiating, and chemotherapeutic agents in triple-negative breast cancer. Breast Cancer Research : Bcr. 20: 145. PMID 30486871 DOI: 10.1186/S13058-018-1068-X |
0.563 |
|
| 2018 |
Wu X, Zahari MS, Renuse S, Sahasrabuddhe NA, Chaerkady R, Kim MS, Fackler MJ, Stampfer M, Gabrielson E, Sukumar S, Pandey A. Correction to: Quantitative phosphoproteomic analysis reveals reciprocal activation of receptor tyrosine kinases between cancer epithelial cells and stromal fibroblasts. Clinical Proteomics. 15: 37. PMID 30479584 DOI: 10.1186/S12014-018-9210-4 |
0.339 |
|
| 2018 |
Lee O, Heinz RE, Ivancic D, Muzzio M, Chatterton RT, Zalles CM, Kenney K, Phan B, Liu D, Scholtens DM, Fackler MJ, Stearns V, Sukumar S, Khan SA. Breast hormone concentrations in random fine needle aspirates of healthy women associate with cytological atypia and gene methylation. Cancer Prevention Research (Philadelphia, Pa.). PMID 29954758 DOI: 10.1158/1940-6207.Capr-17-0323 |
0.517 |
|
| 2018 |
Wu X, Zahari MS, Renuse S, Sahasrabuddhe NA, Chaerkady R, Kim MS, Fackler MJ, Stampfer M, Gabrielson E, Sukumar S, Pandey A. Quantitative phosphoproteomic analysis reveals reciprocal activation of receptor tyrosine kinases between cancer epithelial cells and stromal fibroblasts. Clinical Proteomics. 15: 21. PMID 29946230 DOI: 10.1186/S12014-018-9197-X |
0.428 |
|
| 2018 |
Fackler MJ, Sukumar S. Quantitation of DNA Methylation by Quantitative Multiplex Methylation-Specific PCR (QM-MSP) Assay. Methods in Molecular Biology (Clifton, N.J.). 1708: 473-496. PMID 29224159 DOI: 10.1007/978-1-4939-7481-8_24 |
0.346 |
|
| 2018 |
Fackler M, Downs B, Mercado-Rodriguez C, Cimino-Mathews A, Chen C, Yuan J, Cope L, Kohlway A, Kocmond K, Lai E, Weidler J, Visvanathan K, Umbricht C, Harvey S, Wolff A, ... ... Sukumar S, et al. Abstract P6-03-07: An automated DNA methylation assay (QM-MSP) for rapid breast cancer diagnosis in underdeveloped countries Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P6-03-07 |
0.541 |
|
| 2018 |
Downs BM, Fackler MJ, Mercado-Rodriguez C, Cimino-Mathews A, Chen C, Yuan J, Berg Evd, Cope LM, Harvey SC, Ali SZ, Tulac S, Kocmond KJ, Lai EW, Rhees B, Bates M, ... Sukumar S, et al. Abstract LB-220: An automated breast cancer detection assay for screening in the developing world Cancer Research. 78. DOI: 10.1158/1538-7445.Am2018-Lb-220 |
0.539 |
|
| 2018 |
Pai P, Wang G, Sukumar S. Abstract 4467: The role of HOXA5 in the malignant progression of engineered isogenic MCF10A sublines harboring common breast cancer mutations Cancer Research. 78: 4467-4467. DOI: 10.1158/1538-7445.Am2018-4467 |
0.543 |
|
| 2017 |
Avigdor BE, Cimino-Mathews A, DeMarzo AM, Hicks JL, Shin J, Sukumar S, Fetting J, Argani P, Park BH, Wheelan SJ. Mutational profiles of breast cancer metastases from a rapid autopsy series reveal multiple evolutionary trajectories. Jci Insight. 2. PMID 29263308 DOI: 10.1172/Jci.Insight.96896 |
0.52 |
|
| 2017 |
Connolly RM, Fackler MJ, Zhang Z, Zhou XC, Goetz MP, Boughey JC, Walsh B, Carpenter JT, Storniolo AM, Watkins SP, Gabrielson EW, Stearns V, Sukumar S. Tumor and serum DNA methylation in women receiving preoperative chemotherapy with or without vorinostat in TBCRC008. Breast Cancer Research and Treatment. PMID 28918548 DOI: 10.1007/s10549-017-4503-2 |
0.425 |
|
| 2017 |
Zhang Y, Wei J, Liu S, Wang J, Han X, Qin H, Lang J, Cheng K, Li Y, Qi Y, Anderson GJ, Sukumar S, Li S, Nie G. Inhibition of platelet function using liposomal nanoparticles blocks tumor metastasis. Theranostics. 7: 1062-1071. PMID 28435448 DOI: 10.7150/Thno.17908 |
0.364 |
|
| 2017 |
Merino VF, Cho S, Liang X, Park S, Jin K, Chen Q, Pan D, Zahnow CA, Rein AR, Sukumar S. Inhibitors of STAT3, β-catenin, and IGF-1R sensitize mouse PIK3CA mutant breast cancer to PI3K inhibitors. Molecular Oncology. PMID 28296140 DOI: 10.1002/1878-0261.12053 |
0.473 |
|
| 2017 |
Connolly R, Fackler M, Zhang Z, Zhou X, Goetz M, Boughey J, Walsh B, Carpenter J, Storniolo A, Watkins S, Barielson E, Sukumar S, Stearns V. Abstract P1-09-15: Tumor and serum DNA methylation in women receiving preoperative chemotherapy (PST) with or without vorinostat in primary operable HER2-negative breast cancer in TBCRC008 Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P1-09-15 |
0.505 |
|
| 2016 |
Wu X, Zahari MS, Renuse S, Kelkar DS, Bharbuiya MA, Rojas PL, Stearns V, Gabrielson E, Malla P, Sukumar S, Mahajan NP, Pandey A. The non-receptor tyrosine kinase TNK2/ACK1 is a novel therapeutic target in triple negative breast cancer. Oncotarget. PMID 27902967 DOI: 10.18632/Oncotarget.13579 |
0.586 |
|
| 2016 |
Visvanathan K, Fackler MS, Zhang Z, Lopez-Bujanda ZA, Jeter SC, Sokoll LJ, Garrett-Mayer E, Cope LM, Umbricht CB, Euhus DM, Forero A, Storniolo AM, Nanda R, Lin NU, Carey LA, ... ... Sukumar S, et al. Monitoring of Serum DNA Methylation as an Early Independent Marker of Response and Survival in Metastatic Breast Cancer: TBCRC 005 Prospective Biomarker Study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2015662080. PMID 27870562 DOI: 10.1200/Jco.2015.66.2080 |
0.448 |
|
| 2016 |
Menyhárt O, Harami-Papp H, Sukumar S, Schäfer R, Magnani L, de Barrios O, Győrffy B. Guidelines For The Selection of Functional Assays To Evaluate The Hallmarks of Cancer. Biochimica Et Biophysica Acta. PMID 27742530 DOI: 10.1016/J.Bbcan.2016.10.002 |
0.393 |
|
| 2016 |
Lo PK, Lee JS, Liang X, Sukumar S. The dual role of FOXF2 in regulation of DNA replication and the epithelial-mesenchymal transition in breast cancer progression. Cellular Signalling. PMID 27377963 DOI: 10.1016/J.Cellsig.2016.06.021 |
0.613 |
|
| 2016 |
Sadik H, Korangath P, Nguyen N, Győrffy B, Kumar R, Hedayati M, Teo WW, Park S, Panday H, Gonzalez Munoz T, Menyhart O, Shah N, Pandita RK, Chang JC, DeWeese TL, ... ... Sukumar S, et al. HOXC10 expression supports the development of chemotherapy resistance by fine tuning DNA repair in breast cancer cells. Cancer Research. PMID 27302171 DOI: 10.1158/0008-5472.Can-16-0774 |
0.37 |
|
| 2016 |
Stearns V, Fackler MJ, Hafeez S, Lopez Bujanda Z, Chatterton RT, Jacobs LK, Khouri NF, Ivancic D, Kenney K, Shehata C, Jeter SC, Wolfman JA, Zalles CM, Huang P, Khan SA, ... Sukumar S, et al. Gene Methylation and Cytological Atypia in Random Fine Needle Aspirates for Assessment of Breast Cancer Risk. Cancer Prevention Research (Philadelphia, Pa.). PMID 27261491 DOI: 10.1158/1940-6207.Capr-15-0377 |
0.556 |
|
| 2016 |
Errico MC, Jin K, Sukumar S, Carè A. The Widening Sphere of Influence of HOXB7 in Solid Tumors. Cancer Research. 76: 2857-2862. PMID 27197229 DOI: 10.1158/0008-5472.Can-15-3444 |
0.525 |
|
| 2016 |
Yoshida T, Jin K, Song H, Park S, Huso DL, Zhang Z, Liangfeng H, Zhu C, Bruchertseifer F, Morgenstern A, Sgouros G, Sukumar S. Effective treatment of ductal carcinoma in situ with a HER-2- targeted alpha-particle emitting radionuclide in a preclinical model of human breast cancer. Oncotarget. PMID 27119227 DOI: 10.18632/Oncotarget.8949 |
0.465 |
|
| 2016 |
de Groot JS, Moelans CB, Elias SG, Fackler MJ, van Domselaar R, Suijkerbuijk KP, Witkamp AJ, Sukumar S, van Diest PJ, van der Wall E. DNA promoter hypermethylation in nipple fluid: a potential tool for early breast cancer detection. Oncotarget. PMID 27028854 DOI: 10.18632/Oncotarget.8352 |
0.539 |
|
| 2016 |
Jin K, Sukumar S. HOX genes: Major actors in resistance to selective endocrine response modifiers. Biochimica Et Biophysica Acta. PMID 26803986 DOI: 10.1016/J.Bbcan.2016.01.003 |
0.488 |
|
| 2016 |
Merino VF, Nguyen N, Jin K, Sadik H, Cho S, Korangath P, Han L, Foster YM, Zhou XC, Zhang Z, Connolly R, Stearns V, Ali SZ, Adams C, Chen Q, ... ... Sukumar S, et al. Combined treatment with epigenetic, differentiating, and chemotherapeutic agents cooperatively targets tumor-initiating cells in triple negative breast cancer. Cancer Research. PMID 26787836 DOI: 10.1158/0008-5472.Can-15-1619 |
0.54 |
|
| 2015 |
Jin K, Sukumar S. A pivotal role for HOXB7 protein in endocrine resistant breast cancer. Oncoscience. 2: 917-9. PMID 26697525 |
0.38 |
|
| 2015 |
Li M, Kang JW, Sukumar S, Dasari RR, Barman I. Multiplexed detection of serological cancer markers with plasmon-enhanced Raman spectro-immunoassay. Chemical Science (Royal Society of Chemistry : 2010). 6: 3906-3914. PMID 26405519 DOI: 10.1039/C5Sc01054C |
0.384 |
|
| 2015 |
Wu X, Zahari MS, Ma B, Liu R, Renuse S, Sahasrabuddhe NA, Chen L, Chaerkady R, Kim MS, Zhong J, Jelinek C, Barbhuiya MA, Leal-Rojas P, Yang Y, Kashyap MK, ... ... Sukumar S, et al. Global phosphotyrosine survey in triple-negative breast cancer reveals activation of multiple tyrosine kinase signaling pathways. Oncotarget. PMID 26356563 DOI: 10.18632/Oncotarget.5020 |
0.561 |
|
| 2015 |
Wu X, Zahari MS, Renuse S, Nirujogi RS, Kim MS, Manda SS, Stearns V, Gabrielson E, Sukumar S, Pandey A. Phosphoproteomic Analysis Identifies Focal Adhesion Kinase 2 (FAK2) as a Potential Therapeutic Target for Tamoxifen Resistance in Breast Cancer. Molecular & Cellular Proteomics : McP. 14: 2887-900. PMID 26330541 DOI: 10.1074/Mcp.M115.050484 |
0.523 |
|
| 2015 |
Ding Y, Ji T, Zhao Y, Zhang Y, Zhao X, Zhao R, Lang J, Zhao X, Shi J, Sukumar S, Nie G. Improvement of stability and efficacy of C16Y therapeutic peptide via molecular self-assembly into tumor-responsive nanoformulation. Molecular Cancer Therapeutics. PMID 26269603 DOI: 10.1158/1535-7163.Mct-15-0484 |
0.305 |
|
| 2015 |
Jin K, Park S, Teo WW, Korangath P, Cho SS, Yoshida T, Gyorffy B, Goswami CP, Nakshatri H, Cruz LA, Zhou W, Ji H, Su Y, Ekram M, Wu Z, ... ... Sukumar S, et al. HOXB7 is an ERα cofactor in the activation of HER2 and multiple ER target genes leading to endocrine resistance. Cancer Discovery. PMID 26180042 DOI: 10.1158/2159-8290.Cd-15-0090 |
0.435 |
|
| 2015 |
Su Y, Subedee A, Bloushtain-Qimron N, Savova V, Krzystanek M, Li L, Marusyk A, Tabassum DP, Zak A, Flacker MJ, Li M, Lin JJ, Sukumar S, Suzuki H, Long H, et al. Somatic Cell Fusions Reveal Extensive Heterogeneity in Basal-like Breast Cancer. Cell Reports. 11: 1549-63. PMID 26051943 DOI: 10.1016/J.Celrep.2015.05.011 |
0.55 |
|
| 2015 |
Daemen A, Griffith OL, Heiser LM, Wang NJ, Enache OM, Sanborn Z, Pepin F, Durinck S, Korkola JE, Griffith M, Hur JS, Huh N, Chung J, Cope L, Fackler MJ, ... ... Sukumar S, et al. Erratum to: Modeling precision treatment of breast cancer. Genome Biology. 16: 95. PMID 25962591 DOI: 10.1186/S13059-015-0658-5 |
0.431 |
|
| 2015 |
Korangath P, Teo WW, Sadik H, Han L, Mori N, Huijts CM, Wildes F, Bharti S, Zhang Z, Santa-Maria CA, Tsai H, Dang CV, Stearns V, Bhujwalla ZM, Sukumar S. Targeting Glutamine Metabolism in Breast Cancer with Aminooxyacetate. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 3263-73. PMID 25813021 DOI: 10.1158/1078-0432.Ccr-14-1200 |
0.442 |
|
| 2015 |
Liu S, Jin K, Hui Y, Fu J, Jie C, Feng S, Reisman D, Wang Q, Fan D, Sukumar S, Chen H. HOXB7 promotes malignant progression by activating the TGFβ signaling pathway. Cancer Research. 75: 709-19. PMID 25542862 DOI: 10.1158/0008-5472.Can-14-3100 |
0.577 |
|
| 2015 |
Visvanathan K, Fackler MJ, Zhang Z, Lopez-Bujanda Z, Jeter S, Sokoll LJ, Cope L, Umbricht C, Euhus D, Carpenter JT, Storniolo AM, Nanda R, Lin NU, Carey LA, Ingle JN, ... Sukumar S, et al. DNA methylation in serum as an independent marker of outcome and treatment response in TBCRC 005: A prospective study in metastatic breast cancer (MBC) patients. Journal of Clinical Oncology. 33: 518-518. DOI: 10.1200/Jco.2015.33.15_Suppl.518 |
0.405 |
|
| 2015 |
Merino VF, Nguyen N, Sadik H, Cho S, Cope L, Zhou XC, Zhang Z, Chen Q, Pan D, Huso DL, Ali S, Adams C, Győrffy B, Sukumar S. Abstract 4231: Combination of epigenetic, differentiation and DNA damaging agents induce tumor cell death and stem cell depletion in breast cancer Cancer Research. 75: 4231-4231. DOI: 10.1158/1538-7445.Am2015-4231 |
0.576 |
|
| 2015 |
Teo WW, Merino V, Cho S, Korangath P, Neumann NM, Ewald AJ, Sukumar S. Abstract 1526: HOXA5 inhibits cell plasticity and stemness in breast cancer cells by reinforcing epithelial traits Cancer Research. 75: 1526-1526. DOI: 10.1158/1538-7445.Am2015-1526 |
0.507 |
|
| 2014 |
Teo WW, Sukumar S. Combining the strength of genomics, nanoparticle technology, and direct intraductal delivery for breast cancer treatment. Breast Cancer Research : Bcr. 16: 306. PMID 25927933 DOI: 10.1186/bcr3656 |
0.351 |
|
| 2014 |
Wu X, Zahari MS, Renuse S, Jacob HK, Sakamuri S, Singal M, Gabrielson E, Sukumar S, Pandey A. A breast cancer cell microarray (CMA) as a rapid method to characterize candidate biomarkers. Cancer Biology & Therapy. 15: 1593-9. PMID 25535895 DOI: 10.4161/15384047.2014.961886 |
0.55 |
|
| 2014 |
Barrio-Real L, Benedetti LG, Engel N, Tu Y, Cho S, Sukumar S, Kazanietz MG. Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation. Breast Cancer Research : Bcr. 16: 441. PMID 25248717 DOI: 10.1186/S13058-014-0441-7 |
0.573 |
|
| 2014 |
Wu X, Renuse S, Sahasrabuddhe NA, Zahari MS, Chaerkady R, Kim MS, Nirujogi RS, Mohseni M, Kumar P, Raju R, Zhong J, Yang J, Neiswinger J, Jeong JS, Newman R, ... ... Sukumar S, et al. Activation of diverse signalling pathways by oncogenic PIK3CA mutations. Nature Communications. 5: 4961. PMID 25247763 DOI: 10.1038/Ncomms5961 |
0.32 |
|
| 2014 |
Han L, Diehl A, Nguyen NK, Korangath P, Teo W, Cho S, Kominsky S, Huso DL, Feigenbaum L, Rein A, Argani P, Landberg G, Gessler M, Sukumar S. The Notch pathway inhibits TGFβ signaling in breast cancer through HEYL-mediated crosstalk. Cancer Research. 74: 6509-18. PMID 25217524 DOI: 10.1158/0008-5472.CAN-14-0816 |
0.439 |
|
| 2014 |
Lee E, Fertig EJ, Jin K, Sukumar S, Pandey NB, Popel AS. Breast cancer cells condition lymphatic endothelial cells within pre-metastatic niches to promote metastasis. Nature Communications. 5: 4715. PMID 25178650 DOI: 10.1038/Ncomms5715 |
0.785 |
|
| 2014 |
Cope LM, Fackler MJ, Lopez-Bujanda Z, Wolff AC, Visvanathan K, Gray JW, Sukumar S, Umbricht CB. Do breast cancer cell lines provide a relevant model of the patient tumor methylome? Plos One. 9: e105545. PMID 25157401 DOI: 10.1371/Journal.Pone.0105545 |
0.532 |
|
| 2014 |
Fackler MJ, Lopez Bujanda Z, Umbricht C, Teo WW, Cho S, Zhang Z, Visvanathan K, Jeter S, Argani P, Wang C, Lyman JP, de Brot M, Ingle JN, Boughey J, McGuire K, ... ... Sukumar S, et al. Novel methylated biomarkers and a robust assay to detect circulating tumor DNA in metastatic breast cancer. Cancer Research. 74: 2160-70. PMID 24737128 DOI: 10.1158/0008-5472.Can-13-3392 |
0.501 |
|
| 2014 |
Avraham A, Cho SS, Uhlmann R, Polak ML, Sandbank J, Karni T, Pappo I, Halperin R, Vaknin Z, Sella A, Sukumar S, Evron E. Tissue specific DNA methylation in normal human breast epithelium and in breast cancer. Plos One. 9: e91805. PMID 24651077 DOI: 10.1371/Journal.Pone.0091805 |
0.586 |
|
| 2014 |
Almendro V, Kim HJ, Cheng YK, Gönen M, Itzkovitz S, Argani P, van Oudenaarden A, Sukumar S, Michor F, Polyak K. Genetic and phenotypic diversity in breast tumor metastases. Cancer Research. 74: 1338-48. PMID 24448237 DOI: 10.1158/0008-5472.Can-13-2357-T |
0.466 |
|
| 2014 |
Chalugun P, Shim JS, Korangath PC, Sukumar S, Liu JO. Abstract 443: Synergistic inhibition of HER2 positive breast cancer by triptolide and lapatinib Cancer Research. 74: 443-443. DOI: 10.1158/1538-7445.Am2014-443 |
0.518 |
|
| 2013 |
Daemen A, Griffith OL, Heiser LM, Wang NJ, Enache OM, Sanborn Z, Pepin F, Durinck S, Korkola JE, Griffith M, Hur JS, Huh N, Chung J, Cope L, Fackler MJ, ... ... Sukumar S, et al. Modeling precision treatment of breast cancer. Genome Biology. 14: R110. PMID 24176112 DOI: 10.1186/Gb-2013-14-10-R110 |
0.542 |
|
| 2013 |
Sharma D, Sukumar S. Big punches come in nanosizes for chemoprevention. Cancer Prevention Research (Philadelphia, Pa.). 6: 1007-10. PMID 24072677 DOI: 10.1158/1940-6207.Capr-13-0311 |
0.342 |
|
| 2013 |
Horvath A, Pakala SB, Mudvari P, Reddy SD, Ohshiro K, Casimiro S, Pires R, Fuqua SA, Toi M, Costa L, Nair SS, Sukumar S, Kumar R. Novel insights into breast cancer genetic variance through RNA sequencing. Scientific Reports. 3: 2256. PMID 23884293 DOI: 10.1038/Srep02256 |
0.522 |
|
| 2013 |
Shah N, Jin K, Cruz LA, Park S, Sadik H, Cho S, Goswami CP, Nakshatri H, Gupta R, Chang HY, Zhang Z, Cimino-Mathews A, Cope L, Umbricht C, Sukumar S. HOXB13 mediates tamoxifen resistance and invasiveness in human breast cancer by suppressing ERα and inducing IL-6 expression. Cancer Research. 73: 5449-58. PMID 23832664 DOI: 10.1158/0008-5472.Can-13-1178 |
0.547 |
|
| 2013 |
Choudhury S, Almendro V, Merino VF, Wu Z, Maruyama R, Su Y, Martins FC, Fackler MJ, Bessarabova M, Kowalczyk A, Conway T, Beresford-Smith B, Macintyre G, Cheng YK, Lopez-Bujanda Z, ... ... Sukumar S, et al. Molecular profiling of human mammary gland links breast cancer risk to a p27(+) cell population with progenitor characteristics. Cell Stem Cell. 13: 117-30. PMID 23770079 DOI: 10.1016/J.Stem.2013.05.004 |
0.529 |
|
| 2013 |
Stearns V, Jacobs LK, Fackler M, Tsangaris TN, Rudek MA, Higgins M, Lange J, Cheng Z, Slater SA, Jeter SC, Powers P, Briest S, Chao C, Yoshizawa C, Sugar E, ... ... Sukumar S, et al. Biomarker modulation following short-term vorinostat in women with newly diagnosed primary breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 4008-16. PMID 23719261 DOI: 10.1158/1078-0432.Ccr-13-0033 |
0.551 |
|
| 2013 |
Shah SN, Cope L, Poh W, Belton A, Roy S, Talbot CC, Sukumar S, Huso DL, Resar LMS. HMGA1: A Master Regulator of Tumor Progression in Triple-Negative Breast Cancer Cells Plos One. 8. PMID 23658826 DOI: 10.1371/Journal.Pone.0063419 |
0.554 |
|
| 2013 |
Connolly RM, Nguyen NK, Sukumar S. Molecular pathways: current role and future directions of the retinoic acid pathway in cancer prevention and treatment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 1651-9. PMID 23322901 DOI: 10.1158/1078-0432.Ccr-12-3175 |
0.5 |
|
| 2013 |
Lo PK, Lee JS, Chen H, Reisman D, Berger FG, Sukumar S. Cytoplasmic mislocalization of overexpressed FOXF1 is associated with the malignancy and metastasis of colorectal adenocarcinomas. Experimental and Molecular Pathology. 94: 262-9. PMID 23103611 DOI: 10.1016/J.Yexmp.2012.10.014 |
0.472 |
|
| 2013 |
Merino VF, Nguyen N, Sadik H, Cho S, Zhou XC, Chen Q, Pan D, Sukumar S. Abstract 3726: Combinations of HDAC inhibitor, chemotherapeutic agent and retinoic acid induce growth arrest, differentiation and tumor regression in preclinical models of breast cancer. Cancer Research. 73: 3726-3726. DOI: 10.1158/1538-7445.Am2013-3726 |
0.535 |
|
| 2013 |
Young AC, Ambrosone CB, Sucheston L, Wang D, Yan L, Liu S, Tang L, Freudenheim JL, Shields PG, Morrison CD, Demissie K, Sukumar S, Higgins MJ. Abstract 3641: Genome-wide methylation patterns suggest differences in breast cancer biology in American women of African and European ancestry. Cancer Research. 73: 3641-3641. DOI: 10.1158/1538-7445.Am2013-3641 |
0.537 |
|
| 2013 |
Shah SN, Cope L, Belton A, Poh W, Sukumar S, Huso D, Resar L. Abstract 3122: HMGA1 reprograms breast cancer cells by inducing transcriptional networks involved in an epithelial-mesenchymal transition, stemness, and metastatic progression. Cancer Research. 73: 3122-3122. DOI: 10.1158/1538-7445.Am2013-3122 |
0.588 |
|
| 2013 |
Korangath P, Sadik H, Mori N, Wildes F, Zhang Z, Bhujwalla Z, Sukumar S. Abstract P3-01-01: Targeting glutamine metabolism in breast cancer for therapy Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P3-01-01 |
0.52 |
|
| 2012 |
Kakkad SM, Solaiyappan M, Argani P, Sukumar S, Jacobs LK, Leibfritz D, Bhujwalla ZM, Glunde K. Collagen I fiber density increases in lymph node positive breast cancers: pilot study. Journal of Biomedical Optics. 17: 116017. PMID 23117811 DOI: 10.1117/1.Jbo.17.11.116017 |
0.396 |
|
| 2012 |
Chun YS, Bisht S, Chenna V, Pramanik D, Yoshida T, Hong SM, de Wilde RF, Zhang Z, Huso DL, Zhao M, Rudek MA, Stearns V, Maitra A, Sukumar S. Intraductal administration of a polymeric nanoparticle formulation of curcumin (NanoCurc) significantly attenuates incidence of mammary tumors in a rodent chemical carcinogenesis model: Implications for breast cancer chemoprevention in at-risk populations. Carcinogenesis. 33: 2242-9. PMID 22831956 DOI: 10.1093/Carcin/Bgs248 |
0.461 |
|
| 2012 |
Chun YS, Yoshida T, Mori T, Huso DL, Zhang Z, Stearns V, Perkins B, Jones RJ, Sukumar S. Intraductally administered pegylated liposomal doxorubicin reduces mammary stem cell function in the mammary gland but in the long term, induces malignant tumors. Breast Cancer Research and Treatment. 135: 201-8. PMID 22752247 DOI: 10.1007/S10549-012-2138-X |
0.381 |
|
| 2012 |
Avraham A, Uhlmann R, Shperber A, Birnbaum M, Sandbank J, Sella A, Sukumar S, Evron E. Serum DNA methylation for monitoring response to neoadjuvant chemotherapy in breast cancer patients. International Journal of Cancer. 131: E1166-72. PMID 22407753 DOI: 10.1002/Ijc.27526 |
0.48 |
|
| 2012 |
Jiao X, Wood LD, Lindman M, Jones S, Buckhaults P, Polyak K, Sukumar S, Carter H, Kim D, Karchin R, Sjöblom T. Somatic mutations in the Notch, NF-KB, PIK3CA, and Hedgehog pathways in human breast cancers. Genes, Chromosomes & Cancer. 51: 480-9. PMID 22302350 DOI: 10.1002/Gcc.21935 |
0.516 |
|
| 2012 |
Gao D, Joshi N, Choi H, Ryu S, Hahn M, Catena R, Sadik H, Argani P, Wagner P, Vahdat LT, Port JL, Stiles B, Sukumar S, Altorki NK, Rafii S, et al. Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition. Cancer Research. 72: 1384-94. PMID 22282653 DOI: 10.1158/0008-5472.Can-11-2905 |
0.44 |
|
| 2012 |
Zhou Y, Sridhar R, Shan L, Sha W, Gu X, Sukumar S. Loperamide, an FDA-approved antidiarrhea drug, effectively reverses the resistance of multidrug resistant MCF-7/MDR1 human breast cancer cells to doxorubicin-induced cytotoxicity. Cancer Investigation. 30: 119-25. PMID 22250587 DOI: 10.3109/07357907.2011.640653 |
0.398 |
|
| 2012 |
Singhi AD, Cimino-Mathews A, Jenkins RB, Lan F, Fink SR, Nassar H, Vang R, Fetting JH, Hicks J, Sukumar S, De Marzo AM, Argani P. MYC gene amplification is often acquired in lethal distant breast cancer metastases of unamplified primary tumors. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 25: 378-87. PMID 22056952 DOI: 10.1038/Modpathol.2011.171 |
0.565 |
|
| 2012 |
Lo PK, Lee JS, Sukumar S. The p53-p21WAF1 checkpoint pathway plays a protective role in preventing DNA rereplication induced by abrogation of FOXF1 function. Cellular Signalling. 24: 316-24. PMID 21964066 DOI: 10.1016/J.Cellsig.2011.09.017 |
0.395 |
|
| 2012 |
Zhang H, Wong CC, Wei H, Gilkes DM, Korangath P, Chaturvedi P, Schito L, Chen J, Krishnamachary B, Winnard PT, Raman V, Zhen L, Mitzner WA, Sukumar S, Semenza GL. HIF-1-dependent expression of angiopoietin-like 4 and L1CAM mediates vascular metastasis of hypoxic breast cancer cells to the lungs. Oncogene. 31: 1757-70. PMID 21860410 DOI: 10.1038/Onc.2011.365 |
0.468 |
|
| 2012 |
Jin K, Kong X, Shah T, Penet MF, Wildes F, Sgroi DC, Ma XJ, Huang Y, Kallioniemi A, Landberg G, Bieche I, Wu X, Lobie PE, Davidson NE, Bhujwalla ZM, ... ... Sukumar S, et al. The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway. Proceedings of the National Academy of Sciences of the United States of America. 109: 2736-41. PMID 21690342 DOI: 10.1073/Pnas.1018859108 |
0.51 |
|
| 2012 |
Maruyama R, Shipitsin M, Choudhury S, Wu Z, Protopopov A, Yao J, Lo PK, Bessarabova M, Ishkin A, Nikolsky Y, Liu XS, Sukumar S, Polyak K. Altered antisense-to-sense transcript ratios in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 109: 2820-4. PMID 21098291 DOI: 10.1073/Pnas.1010559107 |
0.487 |
|
| 2012 |
Mori T, Wada S, Olino K, Edil BH, Pardoll DM, Schulick RD, Sukumar S, Yoshimura K. The intraductal injection of 5-fluorouracil for breast cancer: Preventive effect and immune response. Journal of Clinical Oncology. 30. DOI: 10.1200/Jco.2012.30.15_Suppl.E13559 |
0.377 |
|
| 2012 |
Stearns V, Khan SA, Fackler MJ, Chatterton RT, Jacobs LK, Khouri N, Kenney K, Shehata C, Jeter S, Ivancic D, Wolfman J, Zalles CM, Huang P, Sukumar S. Gene methylation in random FNA samples as biomarkers for breast cancer. Journal of Clinical Oncology. 30: 518-518. DOI: 10.1200/Jco.2012.30.15_Suppl.518 |
0.485 |
|
| 2012 |
Jin K, Teo Ww, Yoshida T, Park S, Sukumar S. Abstract 803: HOXB7 functions as a co-activator of estrogen receptor in the development of tamoxifen resistance Cancer Research. 72: 803-803. DOI: 10.1158/1538-7445.Am2012-803 |
0.433 |
|
| 2012 |
Wu X, Renuse S, Chen L, Chaerkady R, Kim M, Zahari S, Sahasrabuddhe N, Zhong J, Yang Y, Kashyap M, Marimuthu A, Ling M, Fackler MJ, Merino V, Zhang Z, ... Sukumar S, et al. Abstract 4797: Global phosphotyrosine survey reveals the evidence of activation of multiple tyrosine kinase signaling pathways in basal-like breast cancer cells Cancer Research. 72: 4797-4797. DOI: 10.1158/1538-7445.Am2012-4797 |
0.527 |
|
| 2012 |
Chatterton R, Sahadevan M, Heinz R, Sukumar S, Stearns V, Fackler M, Lee O, Sivaraman I, Kenney K, Khan S. Abstract P4-12-04: Association of single-strand breaks (SSBs) in normal breast DNA with estimates of breast cancer risk Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P4-12-04 |
0.485 |
|
| 2012 |
Sadik H, Nguyen N, Panday H, Kumar R, Pandita T, Sukumar S. Abstract P4-08-08: HOXC10, a homeobox protein overexpressed in breast cancer, modulates the response to chemotherapy treatment. Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P4-08-08 |
0.592 |
|
| 2012 |
Hu H, Wang J, Lee O, Shidfar A, Iyer S, Ivancic D, Chatterton R, Stearns V, Sukumar S, Khan S. Abstract P3-04-08: Expression of hormone-responsive genes in benign breast tissue varies with menstrual cycle phase and menopausal status Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P3-04-08 |
0.451 |
|
| 2012 |
Ordentlich P, Nguyen N, Jin K, Sadik H, Han L, Sukumar S. Abstract P2-09-01: Reactivation of epigenetically silenced retinoic acid receptor-beta for therapy of breast cancer- from molecular mechanism to potential clinical applications Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P2-09-01 |
0.531 |
|
| 2012 |
Sukumar S, Fackler M, Lopez-Bujanda Z, Teo W, Jeter S, Umbricht C, Visvanathan K, Wolff A. Abstract P2-02-01: Accurate identification of metastatic breast cancer using methylated gene markers in circulating free DNA in peripheral blood Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P2-02-01 |
0.519 |
|
| 2011 |
Stearns V, Mori T, Jacobs LK, Khouri NF, Gabrielson E, Yoshida T, Kominsky SL, Huso DL, Jeter S, Powers P, Tarpinian K, Brown RJ, Lange JR, Rudek MA, Zhang Z, ... ... Sukumar S, et al. Preclinical and clinical evaluation of intraductally administered agents in early breast cancer. Science Translational Medicine. 3: 106ra108. PMID 22030751 DOI: 10.1126/Scitranslmed.3002368 |
0.477 |
|
| 2011 |
Fackler MJ, Umbricht CB, Williams D, Argani P, Cruz LA, Merino VF, Teo WW, Zhang Z, Huang P, Visvananthan K, Marks J, Ethier S, Gray JW, Wolff AC, Cope LM, ... Sukumar S, et al. Genome-wide methylation analysis identifies genes specific to breast cancer hormone receptor status and risk of recurrence. Cancer Research. 71: 6195-207. PMID 21825015 DOI: 10.1158/0008-5472.Can-11-1630 |
0.471 |
|
| 2011 |
Hung T, Wang Y, Lin MF, Koegel AK, Kotake Y, Grant GD, Horlings HM, Shah N, Umbricht C, Wang P, Wang Y, Kong B, Langerød A, Børresen-Dale AL, Kim SK, ... ... Sukumar S, et al. Extensive and coordinated transcription of noncoding RNAs within cell-cycle promoters. Nature Genetics. 43: 621-9. PMID 21642992 DOI: 10.1038/Ng.848 |
0.378 |
|
| 2011 |
Maruyama R, Choudhury S, Kowalczyk A, Bessarabova M, Beresford-Smith B, Conway T, Kaspi A, Wu Z, Nikolskaya T, Merino VF, Lo PK, Liu XS, Nikolsky Y, Sukumar S, Haviv I, et al. Epigenetic regulation of cell type-specific expression patterns in the human mammary epithelium. Plos Genetics. 7: e1001369. PMID 21533021 DOI: 10.1371/Journal.Pgen.1001369 |
0.377 |
|
| 2011 |
Swift-Scanlan T, Vang R, Blackford A, Fackler MJ, Sukumar S. Methylated genes in breast cancer: associations with clinical and histopathological features in a familial breast cancer cohort. Cancer Biology & Therapy. 11: 853-65. PMID 21383541 DOI: 10.4161/Cbt.11.10.15177 |
0.579 |
|
| 2011 |
Sabnis GJ, Goloubeva O, Chumsri S, Nguyen N, Sukumar S, Brodie AM. Functional activation of the estrogen receptor-α and aromatase by the HDAC inhibitor entinostat sensitizes ER-negative tumors to letrozole. Cancer Research. 71: 1893-903. PMID 21245100 DOI: 10.1158/0008-5472.Can-10-2458 |
0.539 |
|
| 2011 |
Sukumar S, Fackler MJ, Cope L, Wolff AW, Huang P, Visvanathan K, Zhang Z, Umbricht C. Abstract CN05-04: Predictive and prognostic methylated gene markers for breast cancer Cancer Prevention Research. 4. DOI: 10.1158/1940-6207.Prev-11-Cn05-04 |
0.537 |
|
| 2011 |
Mori T, Wada S, Olino K, Weber W, Edil B, Meckel K, Pan X, Pardoll D, Schulick R, Sukumar S, Yoshimura K. Abstract LB-456: The intraductal injection of 5-fluorouracil induces immune response to eradicate and prevent breast cancer Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Lb-456 |
0.398 |
|
| 2011 |
Jin K, Zhu T, Lundberg G, Sukumar S. Abstract 745: HOXB7 renders breast cancer resistant to tamoxifen through activation of the HER2 pathway Cancer Research. 71: 745-745. DOI: 10.1158/1538-7445.Am2011-745 |
0.517 |
|
| 2011 |
Korangath PC, Zhang H, Zhang Z, Huso D, Stearns V, Dang C, Semenza G, Sukumar S. Abstract 4088: Targeting glutamine metabolism in breast cancer Cancer Research. 71: 4088-4088. DOI: 10.1158/1538-7445.Am2011-4088 |
0.547 |
|
| 2011 |
Han L, Sukumar S. Abstract 3876: Study the role of HEYL in breast tumorigenesis Cancer Research. 71: 3876-3876. DOI: 10.1158/1538-7445.Am2011-3876 |
0.602 |
|
| 2011 |
Sha W, Gu X, Guo Y, Wang P, Sukumar S, Zhou Y. Abstract 2128: Salvianolic acid B inhibits both ER-α +/- breast cancer cell growthin vivoandin vitro Cancer Research. 71: 2128-2128. DOI: 10.1158/1538-7445.Am2011-2128 |
0.451 |
|
| 2010 |
Wu ZJ, Meyer CA, Choudhury S, Shipitsin M, Maruyama R, Bessarabova M, Nikolskaya T, Sukumar S, Schwartzman A, Liu JS, Polyak K, Liu XS. Gene expression profiling of human breast tissue samples using SAGE-Seq. Genome Research. 20: 1730-9. PMID 21045080 DOI: 10.1101/Gr.108217.110 |
0.538 |
|
| 2010 |
Chen H, Pimienta G, Gu Y, Sun X, Hu J, Kim MS, Chaerkady R, Gucek M, Cole RN, Sukumar S, Pandey A. Proteomic characterization of Her2/neu-overexpressing breast cancer cells. Proteomics. 10: 3800-10. PMID 20960451 DOI: 10.1002/Pmic.201000297 |
0.591 |
|
| 2010 |
Jin K, Sukumar S. BRCA1: Linking HOX to breast cancer suppression Breast Cancer Research. 12. PMID 20727230 DOI: 10.1186/Bcr2600 |
0.573 |
|
| 2010 |
Lo PK, Lee JS, Liang X, Han L, Mori T, Fackler MJ, Sadik H, Argani P, Pandita TK, Sukumar S. Epigenetic inactivation of the potential tumor suppressor gene FOXF1 in breast cancer. Cancer Research. 70: 6047-58. PMID 20587515 DOI: 10.1158/0008-5472.Can-10-1576 |
0.609 |
|
| 2010 |
Lee JS, Fackler MJ, Lee JH, Choi C, Park MH, Yoon JH, Zhang Z, Sukumar S. Basal-like breast cancer displays distinct patterns of promoter methylation. Cancer Biology & Therapy. 9: 1017-24. PMID 20505321 DOI: 10.4161/Cbt.9.12.11804 |
0.569 |
|
| 2010 |
Jacobs L, Sukumar S, Stearns V. Intraductal therapy for the prevention of breast cancer. Current Opinion in Investigational Drugs (London, England : 2000). 11: 646-52. PMID 20496259 |
0.425 |
|
| 2010 |
Kim JH, Choi YD, Lee JS, Lee JH, Nam JH, Choi C, Kweon SS, Fackler MJ, Sukumar S. Quantitative assessment of DNA methylation for the detection of cervical neoplasia in liquid-based cytology specimens. Virchows Archiv : An International Journal of Pathology. 457: 35-42. PMID 20496080 DOI: 10.1007/S00428-010-0936-2 |
0.313 |
|
| 2010 |
Kim JH, Shin MH, Kweon SS, Park MH, Yoon JH, Lee JS, Choi C, Fackler MJ, Sukumar S. Evaluation of promoter hypermethylation detection in serum as a diagnostic tool for breast carcinoma in Korean women. Gynecologic Oncology. 118: 176-81. PMID 20466412 DOI: 10.1016/J.Ygyno.2010.04.016 |
0.479 |
|
| 2010 |
Marik R, Fackler M, Gabrielson E, Zeiger MA, Sukumar S, Stearns V, Umbricht CB. DNA methylation-related vitamin D receptor insensitivity in breast cancer. Cancer Biology & Therapy. 10: 44-53. PMID 20431345 DOI: 10.4161/Cbt.10.1.11994 |
0.594 |
|
| 2010 |
Jin K, Sukumar S. Clonal selection in tamoxifen resistance Cancer Biology and Therapy. 9: 725-727. PMID 20421729 DOI: 10.4161/Cbt.9.9.11952 |
0.472 |
|
| 2010 |
Gupta RA, Shah N, Wang KC, Kim J, Horlings HM, Wong DJ, Tsai MC, Hung T, Argani P, Rinn JL, Wang Y, Brzoska P, Kong B, Li R, West RB, ... ... Sukumar S, et al. Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis. Nature. 464: 1071-6. PMID 20393566 DOI: 10.1038/Nature08975 |
0.533 |
|
| 2010 |
Shah N, Sukumar S. The Hox genes and their roles in oncogenesis. Nature Reviews. Cancer. 10: 361-71. PMID 20357775 DOI: 10.1038/Nrc2826 |
0.338 |
|
| 2010 |
Cimino A, Halushka M, Illei P, Wu X, Sukumar S, Argani P. Epithelial cell adhesion molecule (EpCAM) is overexpressed in breast cancer metastases. Breast Cancer Research and Treatment. 123: 701-8. PMID 20012351 DOI: 10.1007/S10549-009-0671-Z |
0.545 |
|
| 2010 |
Khan SA, Sukumar S, Khouri N, Jacobs LK, Eiring A, Ivancic D, Shehata C, Zalles CM, Chatterton RT, Stearns V. Determinants of low cell yield in random fine needle aspiration (rFNA) procedures of the breast in healthy women unselected by risk. Journal of Clinical Oncology. 28: 1569-1569. DOI: 10.1200/Jco.2010.28.15_Suppl.1569 |
0.422 |
|
| 2010 |
Nguyen NK, Korangath P, Sabnis G, Brodie A, Ordentlich P, Stearns V, Sukumar S. Abstract 5593: A combination of HDAC inhibitor Entinostat (MS-275), All Trans Retinoic Acid (ATRA) and low dose Doxorubicin causes regression of established xenografts of triple negative breast cancer Cancer Research. 70: 5593-5593. DOI: 10.1158/1538-7445.Am10-5593 |
0.511 |
|
| 2010 |
Hillocks YMN, Lo P, Teo WW, Fackler MJ, Sukumar S. Abstract 4916: MAL, a frequently methylated gene marker for early detection of breast cancer Cancer Research. 70: 4916-4916. DOI: 10.1158/1538-7445.Am10-4916 |
0.622 |
|
| 2010 |
Merino V, Park S, Liang X, Chun Y, Jones R, Sukumar S. Abstract P2-07-04: Relevance of Mutated PIK3CA to Normal Mammary Gland Development and Malignancy Cancer Research. 70: 3255-3255. DOI: 10.1158/1538-7445.Am10-3255 |
0.448 |
|
| 2010 |
Jin K, Bhujwalla Z, Sukumar S. Abstract PD05-10: HOXB7 as a Key Regulator in the Development of Tamoxifen Resistance Cancer Research. 70: 608-608. DOI: 10.1158/0008-5472.Sabcs10-Pd05-10 |
0.459 |
|
| 2010 |
Nguyen N, Korangath P, Sabnis G, Brodie A, Ordentlich P, Stearns V, Sukumar S. Abstract PD01-05: A Combination of HDAC Inhibitor Entinostat (MS-275), All Trans Retinoic Acid (ATRA) and Chemotherapy Drug(s) Causes Regression of Established Xenografts of Triple Negative Breast Cancer Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-Pd01-05 |
0.492 |
|
| 2010 |
Sadik H, Shah N, Gupta R, Chang H, Sukumar S. Abstract P4-01-03: The Homeobox Protein H0XC10 Is Overexpressed in Breast Cancer and Confers Resistance to Chemotherapy Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P4-01-03 |
0.498 |
|
| 2010 |
Hillocks Y, Lo P, Teo W, Fackler M, Sukumar S. Abstract P3-04-06: A Functional Investigation of MAL: A Frequently Hypermethylated Gene Marker in Breast Cancer Cancer Research. 70. DOI: 10.1158/0008-5472.Sabcs10-P3-04-06 |
0.629 |
|
| 2009 |
Jacobs LK, Khouri N, Jeter S, Powers P, Rudek M, Gabrielson E, Zhang Z, Sukumar S, Tsangaris T, Stearns V. A phase I study assessing the feasibility and safety of intraductal pegylated liposomal doxorubicin (PLD) in women with breast cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: e11506. PMID 27964594 DOI: 10.1200/Jco.2009.27.15_Suppl.E11506 |
0.518 |
|
| 2009 |
Mankoo PK, Sukumar S, Karchin R. PIK3CA somatic mutations in breast cancer: Mechanistic insights from Langevin dynamics simulations. Proteins. 75: 499-508. PMID 18951408 DOI: 10.1002/Prot.22265 |
0.407 |
|
| 2009 |
Sukumar S. DNA Methylation – Role in Gene Regulation and Detection Methods. Cancer Research. 69. DOI: 10.1158/0008-5472.Sabcs-09-Es4-1 |
0.41 |
|
| 2009 |
Sabnis G, Goloubeva O, Gilani R, Nguyen N, Chumsri S, Macedo L, Sukumar S, Brodie A. Expression of ERα and Aromatase in MDA-MB-231 Tumors by HDAC Inhibitor Entinostat Leads to Growth Inhibition by Aromatase Inhibitor Letrozole. Cancer Research. 69: 401-401. DOI: 10.1158/0008-5472.Sabcs-09-401 |
0.463 |
|
| 2008 |
Lo PK, Sukumar S. Epigenomics and breast cancer. Pharmacogenomics. 9: 1879-902. PMID 19072646 DOI: 10.2217/14622416.9.12.1879 |
0.57 |
|
| 2008 |
Cao D, Polyak K, Halushka MK, Nassar H, Kouprina N, Iacobuzio-Donahue C, Wu X, Sukumar S, Hicks J, De Marzo A, Argani P. Serial analysis of gene expression of lobular carcinoma in situ identifies down regulation of claudin 4 and overexpression of matrix metalloproteinase 9. Breast Cancer Research : Bcr. 10: R91. PMID 18954444 DOI: 10.1186/Bcr2189 |
0.432 |
|
| 2008 |
Marlow R, Strickland P, Lee JS, Wu X, Pebenito M, Binnewies M, Le EK, Moran A, Macias H, Cardiff RD, Sukumar S, Hinck L. SLITs suppress tumor growth in vivo by silencing Sdf1/Cxcr4 within breast epithelium. Cancer Research. 68: 7819-27. PMID 18829537 DOI: 10.1158/0008-5472.Can-08-1357 |
0.561 |
|
| 2008 |
Bloushtain-Qimron N, Yao J, Snyder EL, Shipitsin M, Campbell LL, Mani SA, Hu M, Chen H, Ustyansky V, Antosiewicz JE, Argani P, Halushka MK, Thomson JA, Pharoah P, Porgador A, ... Sukumar S, et al. Cell type-specific DNA methylation patterns in the human breast. Proceedings of the National Academy of Sciences of the United States of America. 105: 14076-81. PMID 18780791 DOI: 10.1073/Pnas.0805206105 |
0.429 |
|
| 2008 |
Lee JS, Fackler MJ, Teo WW, Lee JH, Choi C, Park MH, Yoon JH, Zhang Z, Argani P, Sukumar S. Quantitative promoter hypermethylation profiles of ductal carcinoma in situ in North American and Korean women: Potential applications for diagnosis. Cancer Biology & Therapy. 7: 1398-406. PMID 18769130 DOI: 10.4161/cbt.7.9.6425 |
0.31 |
|
| 2008 |
Suijkerbuijk KPM, Fackler MJ, Sukumar S, Gils CHv, Laar Tv, Wall Evd, Vooijs M, Diest PJv. Methylation is less abundant in BRCA1-associated compared with sporadic breast cancer Annals of Oncology. 19: 1870-1874. PMID 18647968 DOI: 10.1093/Annonc/Mdn409 |
0.567 |
|
| 2008 |
Winnard PT, Sukumar S. A PET rat model for assessing the effectiveness of new chemotherapies. Cancer Biology & Therapy. 7: 538-9. PMID 18627116 DOI: 10.4161/Cbt.7.4.5642 |
0.419 |
|
| 2008 |
Chen H, Lee JS, Liang X, Zhang H, Zhu T, Zhang Z, Taylor ME, Zahnow C, Feigenbaum L, Rein A, Sukumar S. Hoxb7 inhibits transgenic HER-2/neu-induced mouse mammary tumor onset but promotes progression and lung metastasis. Cancer Research. 68: 3637-44. PMID 18463397 DOI: 10.1158/0008-5472.Can-07-2926 |
0.488 |
|
| 2008 |
Wu JM, Fackler MJ, Halushka MK, Molavi DW, Taylor ME, Teo WW, Griffin C, Fetting J, Davidson NE, De Marzo AM, Hicks JL, Chitale D, Ladanyi M, Sukumar S, Argani P. Heterogeneity of breast cancer metastases: comparison of therapeutic target expression and promoter methylation between primary tumors and their multifocal metastases. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 1938-46. PMID 18381931 DOI: 10.1158/1078-0432.Ccr-07-4082 |
0.475 |
|
| 2008 |
Gupta A, Guerin-Peyrou TG, Sharma GG, Park C, Agarwal M, Ganju RK, Pandita S, Choi K, Sukumar S, Pandita RK, Ludwig T, Pandita TK. The mammalian ortholog of Drosophila MOF that acetylates histone H4 lysine 16 is essential for embryogenesis and oncogenesis. Molecular and Cellular Biology. 28: 397-409. PMID 17967868 DOI: 10.1128/Mcb.01045-07 |
0.378 |
|
| 2008 |
Prowell TM, Fackler M, Argani P, Khouri NF, Blackford AL, Shahverdi K, Wolff AC, Davidson NE, Sukumar S, Stearns V. A prospective study of adjuvant anastrozole and gene promoter methylation in the contralateral breast of high-risk women Journal of Clinical Oncology. 26: 1514-1514. DOI: 10.1200/Jco.2008.26.15_Suppl.1514 |
0.538 |
|
| 2008 |
Sukumar S, Stearns V, Khouri N, Jacobs L, Jeter S, Powers P, Rudek M, Gabrielson E, Zhang Z, Tsangaris T. Abstract CN13-03: Intraductal route of breast cancer prevention and therapy: from preclinical studies to Phase I trials Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-Cn13-03 |
0.527 |
|
| 2008 |
Marik R, Sukumar S, Zeiger M, Stearns V, Umbricht C. Abstract A50: Soy isoflavones and vitamin D in breast cancer prevention. Cancer Prevention Research. 1. DOI: 10.1158/1940-6207.Prev-08-A50 |
0.588 |
|
| 2007 |
Wood LD, Parsons DW, Jones S, Lin J, Sjöblom T, Leary RJ, Shen D, Boca SM, Barber T, Ptak J, Silliman N, Szabo S, Dezso Z, Ustyanksky V, Nikolskaya T, ... ... Sukumar S, et al. The genomic landscapes of human breast and colorectal cancers. Science (New York, N.Y.). 318: 1108-13. PMID 17932254 DOI: 10.1126/science.1145720 |
0.412 |
|
| 2007 |
Chen H, Zhang H, Lee J, Liang X, Wu X, Zhu T, Lo PK, Zhang X, Sukumar S. HOXA5 acts directly downstream of retinoic acid receptor beta and contributes to retinoic acid-induced apoptosis and growth inhibition. Cancer Research. 67: 8007-13. PMID 17804711 DOI: 10.1158/0008-5472.Can-07-1405 |
0.499 |
|
| 2007 |
Kominsky SL, Tyler B, Sosnowski J, Brady K, Doucet M, Nell D, Smedley JG, McClane B, Brem H, Sukumar S. Clostridium perfringens enterotoxin as a novel-targeted therapeutic for brain metastasis. Cancer Research. 67: 7977-82. PMID 17804705 DOI: 10.1158/0008-5472.Can-07-1314 |
0.505 |
|
| 2007 |
Lee JS, Lo PK, Fackler MJ, Argani P, Zhang Z, Garrett-Meyer E, Sukumar S. A comparative study of Korean with Caucasian breast cancer reveals frequency of methylation in multiple genes correlates with breast cancer in young, ER, PR-negative breast cancer in Korean women. Cancer Biology & Therapy. 6: 1114-20. PMID 17611401 DOI: 10.4161/Cbt.6.7.4331 |
0.549 |
|
| 2007 |
Shipitsin M, Campbell LL, Argani P, Weremowicz S, Bloushtain-Qimron N, Yao J, Nikolskaya T, Serebryiskaya T, Beroukhim R, Hu M, Halushka MK, Sukumar S, Parker LM, Anderson KS, Harris LN, et al. Molecular definition of breast tumor heterogeneity. Cancer Cell. 11: 259-73. PMID 17349583 DOI: 10.1016/J.Ccr.2007.01.013 |
0.475 |
|
| 2007 |
Wu X, Sukumar S. ETS genes in breast cancer: a step in the right direction. Cancer Biology & Therapy. 6: 83-4. PMID 17297305 DOI: 10.4161/Cbt.6.1.3825 |
0.494 |
|
| 2007 |
Mohankumar KM, Xu XQ, Zhu T, Kannan N, Miller LD, Liu ET, Gluckman PD, Sukumar S, Emerald BS, Lobie PE. HOXA1-stimulated oncogenicity is mediated by selective upregulation of components of the p44/42 MAP kinase pathway in human mammary carcinoma cells. Oncogene. 26: 3998-4008. PMID 17213808 DOI: 10.1038/Sj.Onc.1210180 |
0.342 |
|
| 2006 |
Visvanathan K, Sukumar S, Davidson NE. Epigenetic biomarkers and breast cancer: cause for optimism. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 6591-3. PMID 17121875 DOI: 10.1158/1078-0432.Ccr-06-2001 |
0.469 |
|
| 2006 |
Wu G, Guo Z, Chatterjee A, Huang X, Rubin E, Wu F, Mambo E, Chang X, Osada M, Sook Kim M, Moon C, Califano JA, Ratovitski EA, Gollin SM, Sukumar S, et al. Overexpression of glycosylphosphatidylinositol (GPI) transamidase subunits phosphatidylinositol glycan class T and/or GPI anchor attachment 1 induces tumorigenesis and contributes to invasion in human breast cancer. Cancer Research. 66: 9829-36. PMID 17047043 DOI: 10.1158/0008-5472.Can-06-0506 |
0.554 |
|
| 2006 |
Wu X, Chen H, Parker B, Rubin E, Zhu T, Lee JS, Argani P, Sukumar S. HOXB7, a homeodomain protein, is overexpressed in breast cancer and confers epithelial-mesenchymal transition. Cancer Research. 66: 9527-34. PMID 17018609 DOI: 10.1158/0008-5472.Can-05-4470 |
0.52 |
|
| 2006 |
Lau QC, Raja E, Salto-Tellez M, Liu Q, Ito K, Inoue M, Putti TC, Loh M, Ko TK, Huang C, Bhalla KN, Zhu T, Ito Y, Sukumar S. RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer. Cancer Research. 66: 6512-20. PMID 16818622 DOI: 10.1158/0008-5472.Can-06-0369 |
0.596 |
|
| 2006 |
Fackler MJ, Malone K, Zhang Z, Schilling E, Garrett-Mayer E, Swift-Scanlan T, Lange J, Nayar R, Davidson NE, Khan SA, Sukumar S. Quantitative multiplex methylation-specific PCR analysis doubles detection of tumor cells in breast ductal fluid. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 3306-10. PMID 16740751 DOI: 10.1158/1078-0432.Ccr-05-2733 |
0.549 |
|
| 2006 |
Lorincz AM, Sukumar S. Molecular links between obesity and breast cancer Endocrine-Related Cancer. 13: 279-292. PMID 16728564 DOI: 10.1677/Erc.1.00729 |
0.477 |
|
| 2006 |
Huang Y, Keen JC, Pledgie A, Marton LJ, Zhu T, Sukumar S, Park BH, Blair B, Brenner K, Casero RA, Davidson NE. Polyamine analogues down-regulate estrogen receptor alpha expression in human breast cancer cells. The Journal of Biological Chemistry. 281: 19055-63. PMID 16679312 DOI: 10.1074/Jbc.M600910200 |
0.526 |
|
| 2006 |
Liang X, Lau QC, Salto-Tellez M, Putti TC, Loh M, Sukumar S. Mutational hotspot in exon 20 of PIK3CA in breast cancer among Singapore Chinese. Cancer Biology & Therapy. 5: 544-8. PMID 16582596 DOI: 10.4161/Cbt.5.5.2656 |
0.566 |
|
| 2006 |
Swift-Scanlan T, Blackford A, Argani P, Sukumar S, Fackler MJ. Two-color quantitative multiplex methylation-specific PCR. Biotechniques. 40: 210-9. PMID 16526411 DOI: 10.2144/000112097 |
0.302 |
|
| 2006 |
Murata S, Kominsky SL, Vali M, Zhang Z, Garrett-Mayer E, Korz D, Huso D, Baker SD, Barber J, Jaffee E, Reilly RT, Sukumar S. Ductal access for prevention and therapy of mammary tumors Cancer Research. 66: 638-645. PMID 16423990 DOI: 10.1158/0008-5472.Can-05-4329 |
0.539 |
|
| 2006 |
Lo PK, Mehrotra J, D'Costa A, Fackler MJ, Garrett-Mayer E, Argani P, Sukumar S. Epigenetic suppression of secreted frizzled related protein 1 (SFRP1) expression in human breast cancer. Cancer Biology & Therapy. 5: 281-6. PMID 16410723 DOI: 10.4161/Cbt.5.3.2384 |
0.623 |
|
| 2005 |
Li J, Zhao J, Yu X, Lange J, Kuerer H, Krishnamurthy S, Schilling E, Khan SA, Sukumar S, Chan DW. Identification of biomarkers for breast cancer in nipple aspiration and ductal lavage fluid. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 8312-20. PMID 16322290 DOI: 10.1158/1078-0432.Ccr-05-1538 |
0.51 |
|
| 2005 |
Davidson NE, Sukumar S. Of Snail, mice, and women. Cancer Cell. 8: 173-174. PMID 16169460 DOI: 10.1016/J.Ccr.2005.08.006 |
0.557 |
|
| 2005 |
Wu G, Xing M, Mambo E, Huang X, Liu J, Guo Z, Chatterjee A, Goldenberg D, Gollin SM, Sukumar S, Trink B, Sidransky D. Somatic mutation and gain of copy number of PIK3CA in human breast cancer. Breast Cancer Research : Bcr. 7: R609-16. PMID 16168105 DOI: 10.1186/Bcr1262 |
0.497 |
|
| 2005 |
Huang Y, Pledgie A, Rubin E, Marton LJ, Woster PM, Sukumar S, Casero RA, Davidson NE. Role of p53/p21Waf1/Cip1 in the regulation of polyamine analogue-induced growth inhibition and cell death in human breast cancer cells Cancer Biology and Therapy. 4: 1006-1013. PMID 16131835 DOI: 10.4161/Cbt.4.9.1970 |
0.459 |
|
| 2005 |
Mambo E, Chatterjee A, Xing M, Tallini G, Haugen BR, Yeung SC, Sukumar S, Sidransky D. Tumor-specific changes in mtDNA content in human cancer. International Journal of Cancer. 116: 920-4. PMID 15856456 DOI: 10.1002/Ijc.21110 |
0.443 |
|
| 2005 |
Chen H, Rubin E, Zhang H, Chung S, Jie CC, Garrett E, Biswal S, Sukumar S. Identification of transcriptional targets of HOXA5. The Journal of Biological Chemistry. 280: 19373-80. PMID 15757903 DOI: 10.1074/Jbc.M413528200 |
0.405 |
|
| 2004 |
Parker BS, Argani P, Cook BP, Liangfeng H, Chartrand SD, Zhang M, Saha S, Bardelli A, Jiang Y, St Martin TB, Nacht M, Teicher BA, Klinger KW, Sukumar S, Madden SL. Alterations in vascular gene expression in invasive breast carcinoma. Cancer Research. 64: 7857-66. PMID 15520192 DOI: 10.1158/0008-5472.Can-04-1976 |
0.564 |
|
| 2004 |
Bae YK, Brown A, Garrett E, Bornman D, Fackler MJ, Sukumar S, Herman JG, Gabrielson E. Hypermethylation in histologically distinct classes of breast cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 5998-6005. PMID 15447983 DOI: 10.1158/1078-0432.Ccr-04-0667 |
0.579 |
|
| 2004 |
Fackler MJ, McVeigh M, Mehrotra J, Blum MA, Lange J, Lapides A, Garrett E, Argani P, Sukumar S. Quantitative Multiplex Methylation-Specific PCR Assay for the Detection of Promoter Hypermethylation in Multiple Genes in Breast Cancer Cancer Research. 64: 4442-4452. PMID 15231653 DOI: 10.1158/0008-5472.Can-03-3341 |
0.538 |
|
| 2004 |
Leighton X, Srikantan V, Pollard HB, Sukumar S, Srivastava M. Significant allelic loss of ANX7region (10q21) in hormone receptor negative breast carcinomas. Cancer Letters. 210: 239-244. PMID 15183540 DOI: 10.1016/J.Canlet.2004.01.018 |
0.461 |
|
| 2004 |
Mehrotra J, Vali M, McVeigh M, Kominsky SL, Fackler MJ, Lahti-Domenici J, Polyak K, Sacchi N, Garrett-Mayer E, Argani P, Sukumar S. Very High Frequency of Hypermethylated Genes in Breast Cancer Metastasis to the Bone, Brain, and Lung Clinical Cancer Research. 10: 3104-3109. PMID 15131050 DOI: 10.1158/1078-0432.Ccr-03-0118 |
0.484 |
|
| 2004 |
Kominsky SL, Vali M, Korz D, Gabig TG, Weitzman SA, Argani P, Sukumar S. Clostridium perfringens enterotoxin elicits rapid and specific cytolysis of breast carcinoma cells mediated through tight junction proteins claudin 3 and 4. The American Journal of Pathology. 164: 1627-33. PMID 15111309 DOI: 10.1016/S0002-9440(10)63721-2 |
0.577 |
|
| 2004 |
Mehrotra J, Ganpat MM, Kanaan Y, Fackler MJ, McVeigh M, Lahti-Domenici J, Polyak K, Argani P, Naab T, Garrett E, Parmigiani G, Broome C, Sukumar S. Estrogen receptor/progesterone receptor-negative breast cancers of young African-American women have a higher frequency of methylation of multiple genes than those of Caucasian women. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 2052-7. PMID 15041725 DOI: 10.1158/1078-0432.Ccr-03-0514 |
0.459 |
|
| 2004 |
Zhu T, Sukumar S. Coupling the transcriptional regulatory action of Brn-3b to the cell cycle clock. Cancer Biology & Therapy. 3: 324-5. PMID 15020847 DOI: 10.4161/Cbt.3.3.763 |
0.452 |
|
| 2004 |
Chen H, Chung S, Sukumar S. HOXA5-induced apoptosis in breast cancer cells is mediated by caspases 2 and 8. Molecular and Cellular Biology. 24: 924-935. PMID 14701762 DOI: 10.1128/Mcb.24.2.924-935.2004 |
0.397 |
|
| 2004 |
Parker BS, Argani P, Cook BP, Liangfeng H, Chartrand SD, Zhang M, Saha S, Bardelli A, Jiang Y, Martin TBS, Nacht M, Teicher BA, Klinger KW, Sukumar S, Madden SL. Erratum: Alterations in vascular gene expression in invasive breast carcinoma (Cancer Research (November 1, 2004) 64, 1 (7857-7866)) Cancer Research. 64. DOI: 10.1158/0008-5472.Can-64-23-Cor |
0.516 |
|
| 2004 |
Fackler MJ, McVeigh M, Mehrotra J, Blum MA, Lange J, Lapides A, Garret E, Argani P, Sukumar S, D'Agostino L. Quantitative multiplex methylation-specific PCR assay for the detection of promoter hypermethylation in multiple genes in breast cancer The Women's Oncology Review. 4: 183-185. DOI: 10.1080/14733400412331313124 |
0.521 |
|
| 2003 |
Chen H, Sukumar S. Role of Homeobox Genes in Normal Mammary Gland Development and Breast Tumorigenesis Journal of Mammary Gland Biology and Neoplasia. 8: 159-175. PMID 14635792 DOI: 10.1023/A:1025996707117 |
0.486 |
|
| 2003 |
Chen H, Sukumar S. HOX genes: emerging stars in cancer. Cancer Biology & Therapy. 2: 524-525. PMID 14614319 DOI: 10.4161/Cbt.2.5.525 |
0.494 |
|
| 2003 |
Pu RT, Laitala LE, Alli PM, Fackler MJ, Sukumar S, Clark DP. Methylation profiling of benign and malignant breast lesions and its application to cytopathology. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 16: 1095-101. PMID 14614048 DOI: 10.1097/01.Mp.0000095782.79895.E2 |
0.477 |
|
| 2003 |
Fackler MJ, McVeigh M, Evron E, Garrett E, Mehrotra J, Polyak K, Sukumar S, Argani P. DNA methylation of RASSF1A, HIN-1, RAR-β, cyclin D2 and twist in in situ and invasive lobular breast carcinoma International Journal of Cancer. 107: 970-975. PMID 14601057 DOI: 10.1002/Ijc.11508 |
0.513 |
|
| 2003 |
Fackler MJ, Evron E, Khan SA, Sukumar S. Novel agents for chemoprevention, screening methods, and sampling issues. Journal of Mammary Gland Biology and Neoplasia. 8: 75-89. PMID 14587864 DOI: 10.1023/A:1025735405628 |
0.413 |
|
| 2003 |
Parker BS, Cutts SM, Nudelman A, Rephaeli A, Phillips DR, Sukumar S. Mitoxantrone mediates demethylation and reexpression of cyclin d2, estrogen receptor and 14.3.3sigma in breast cancer cells. Cancer Biology & Therapy. 2: 259-63. PMID 12878861 DOI: 10.4161/Cbt.2.3.364 |
0.504 |
|
| 2003 |
Loeb DM, Summers JL, Burwell EA, Korz D, Friedman AD, Sukumar S. An isoform of the Wilms' tumor suppressor gene potentiates granulocytic differentiation Leukemia. 17: 965-971. PMID 12750711 DOI: 10.1038/Sj.Leu.2402906 |
0.353 |
|
| 2003 |
Kominsky SL, Argani P, Korz D, Evron E, Raman V, Garrett E, Rein A, Sauter G, Kallioniemi OP, Sukumar S. Loss of the tight junction protein claudin-7 correlates with histological grade in both ductal carcinoma in situ and invasive ductal carcinoma of the breast. Oncogene. 22: 2021-33. PMID 12673207 DOI: 10.1038/Sj.Onc.1206199 |
0.53 |
|
| 2003 |
Parker BS, Sukumar S. Distant metastasis in breast cancer: molecular mechanisms and therapeutic targets. Cancer Biology & Therapy. 2: 14-21. PMID 12673112 DOI: 10.4161/Cbt.188 |
0.539 |
|
| 2002 |
Loeb DM, Sukumar S. The role of WT1 in oncogenesis: tumor suppressor or oncogene? International Journal of Hematology. 76: 117-126. PMID 12215009 DOI: 10.1007/Bf02982573 |
0.46 |
|
| 2002 |
Loeb DM, Korz D, Katsnelson M, Burwell EA, Friedman AD, Sukumar S. Cyclin E is a target of WT1 transcriptional repression. Journal of Biological Chemistry. 277: 19627-19632. PMID 11919196 DOI: 10.1074/Jbc.M201336200 |
0.359 |
|
| 2001 |
Umbricht CB, Evron E, Gabrielson E, Ferguson A, Marks J, Sukumar S. Hypermethylation of 14-3-3 sigma (stratifin) is an early event in breast cancer. Oncogene. 20: 3348-53. PMID 11423985 DOI: 10.1038/Sj.Onc.1204438 |
0.578 |
|
| 2001 |
Evron E, Dooley WC, Umbricht CB, Rosenthal D, Sacchi N, Gabrielson E, Soito AB, Hung DT, Ljung BM, Davidson NE, Sukumar S. Detection of breast cancer cells in ductal lavage fluid by methylation-specific PCR The Lancet. 357: 1335-1336. PMID 11343741 DOI: 10.1016/S0140-6736(00)04501-3 |
0.537 |
|
| 2000 |
Raman V, Martensen SA, Reisman D, Evron E, Odenwald WF, Jaffee E, Marks J, Sukumar S. Compromised HOXA5 function can limit p53 expression in human breast tumours. Nature. 405: 974-8. PMID 10879542 DOI: 10.1038/35016125 |
0.492 |
|
| 2000 |
Raman V, Tamori A, Vali M, Zeller K, Korz D, Sukumar S. HOXA5 regulates expression of the progesterone receptor. Journal of Biological Chemistry. 275: 26551-26555. PMID 10875927 DOI: 10.1074/Jbc.C000324200 |
0.534 |
|
| 2000 |
Ferguson AT, Evron E, Umbricht CB, Pandita TK, Chan TA, Hermeking H, Marks JR, Lambers AR, Futreal PA, Stampfer MR, Sukumar S. High frequency of hypermethylation at the 14-3-3 sigma locus leads to gene silencing in breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 97: 6049-54. PMID 10811911 DOI: 10.1073/Pnas.100566997 |
0.584 |
|
| 2000 |
Sirchia SM, Ferguson AT, Sironi E, Subramanyan S, Orlandi R, Sukumar S, Sacchi N. Evidence of epigenetic changes affecting the chromatin state of the retinoic acid receptor β2 promoter in breast cancer cells Oncogene. 19: 1556-1563. PMID 10734315 DOI: 10.1038/Sj.Onc.1203456 |
0.526 |
|
| 1999 |
Carey LA, Kim NW, Goodman S, Marks J, Henderson G, Umbricht CB, Dome JS, Dooley W, Amshey SR, Sukumar S. Telomerase activity and prognosis in primary breast cancers. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 17: 3075-81. PMID 10506602 DOI: 10.1200/Jco.1999.17.10.3075 |
0.516 |
|
| 1999 |
Umbricht CB, Sherman ME, Dome J, Carey LA, Marks J, Kim N, Sukumar S. Telomerase activity in ductal carcinoma in situ and invasive breast cancer Oncogene. 18: 3407-3414. PMID 10362362 DOI: 10.1038/Sj.Onc.1202714 |
0.507 |
|
| 1999 |
Sawant SG, Gregoire V, Dhar S, Umbricht CB, Cvilic S, Sukumar S, Pandita TK. Telomerase activity as a measure for monitoring radiocurability of tumor cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 13: 1047-54. PMID 10336887 DOI: 10.1096/Fasebj.13.9.1047 |
0.342 |
|
| 1999 |
McKenzie KE, Umbricht CB, Sukumar S. Applications of telomerase research in the fight against cancer Molecular Medicine Today. 5: 114-122. PMID 10203735 DOI: 10.1016/S1357-4310(98)01429-4 |
0.448 |
|
| 1998 |
Trink B, Pai SI, Spunt SL, Raman V, Cairns P, Jen J, Gabrielson E, Sukumar S, Sidransky D. Absence of TSG101 transcript abnormalities in human cancers Oncogene. 16: 2815-2818. PMID 9652749 DOI: 10.1038/Sj.Onc.1201795 |
0.575 |
|
| 1998 |
Webster NJ, Kong Y, Sharma P, Haas M, Sukumar S, Seely BL. Differential effects of Wilms tumor WT1 splice variants on the insulin receptor promoter. Biochemical and Molecular Medicine. 62: 139-50. PMID 9441865 DOI: 10.1006/Bmme.1997.2648 |
0.344 |
|
| 1997 |
McKenzie KE, Armstrong BA, Chen Y, Nagarajan M, Aldaz CM, Sukumar S. Alterations in the Ha-ras-1 and the p53 pathway genes in the progression of N-methyl-N-nitrosourea-induced rat mammary tumors Molecular Carcinogenesis. 20: 194-203. PMID 9364209 DOI: 10.1002/(Sici)1098-2744(199710)20:2<194::Aid-Mc6>3.0.Co;2-N |
0.376 |
|
| 1996 |
Chen Y, McKenzie KE, Aldaz CM, Sukumar S. Midkine in the progression of rat N-nitroso-N-methylurea-induced mammary tumors Molecular Carcinogenesis. 17: 112-116. PMID 8944070 DOI: 10.1002/(Sici)1098-2744(199611)17:3<112::Aid-Mc2>3.0.Co;2-H |
0.516 |
|
| 1995 |
Sukumar S, McKenzie K, Chen Y. Animal models for breast cancer Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis. 333: 37-44. PMID 8538634 DOI: 10.1016/0027-5107(95)00129-8 |
0.461 |
|
| 1994 |
McKenzie K, Sukumar S. Molecular mechanisms of chemical carcinogenesis in rodent models Cancer Treatment and Research. 71: 313-329. PMID 7946956 DOI: 10.1007/978-1-4615-2592-9_17 |
0.379 |
|
| 1994 |
Sharma PM, Bowman M, Yu B, Sukumar S. A rodent model for Wilms tumors: embryonal kidney neoplasms induced by N-nitroso-N'-methylurea Proceedings of the National Academy of Sciences of the United States of America. 91: 9931-9935. PMID 7937920 DOI: 10.1073/Pnas.91.21.9931 |
0.339 |
|
| 1992 |
Soto D, Sukumar S. Improved detection of mutations in the p53 gene in human tumors as single-stranded conformation polymorphs and double-stranded heteroduplex DNA. Pcr Methods and Applications. 2: 96-8. PMID 1490183 DOI: 10.1101/Gr.2.1.96 |
0.408 |
|
| 1991 |
Garlick DS, Sukumar S, Barbacid M, Petit D, Hamer PJ, Leav I, Lavecchio JA, Trimpe KL, Carney WP. Generation of monoclonal antibodies specific for ras p21 Glu-12 oncoproteins: detection in carcinogen-induced mammary carcinomas. Hybridoma. 10: 95-102. PMID 2032737 DOI: 10.1089/Hyb.1991.10.95 |
0.341 |
|
| 1991 |
Runnebaum IB, Nagarajan M, Bowman M, Soto D, Sukumar S. Mutations in p53 as potential molecular markers for human breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 88: 10657-61. PMID 1961733 DOI: 10.1073/Pnas.88.23.10657 |
0.517 |
|
| 1991 |
Sukumar S, Armstrong B, Bruyntjes JP, Leav I, Bosland MC. Frequent activation of the Ki-ras oncogene at codon 12 in N-methyl-N-nitrosourea-induced rat prostate adenocarcinomas and neurogenic sarcomas. Molecular Carcinogenesis. 4: 362-368. PMID 1680340 DOI: 10.1002/Mc.2940040507 |
0.306 |
|
| 1990 |
Sukumar S, Barbacid M. Specific patterns of oncogene activation in transplacentally induced tumors. Proceedings of the National Academy of Sciences of the United States of America. 87: 718-22. PMID 2405388 DOI: 10.1073/Pnas.87.2.718 |
0.351 |
|
| 1988 |
Sukumar S, Carney WP, Barbacid M. Independent molecular pathways in initiation and loss of hormone responsiveness of breast carcinomas. Science (New York, N.Y.). 240: 524-6. PMID 3282307 DOI: 10.1126/Science.3282307 |
0.512 |
|
| 1986 |
Sukumar S, Perantoni A, Reed C, Rice JM, Wenk ML. Activated K-ras and N-ras oncogenes in primary renal mesenchymal tumors induced in F344 rats by methyl(methoxymethyl)nitrosamine. Molecular and Cellular Biology. 6: 2716-2720. PMID 3785207 DOI: 10.1128/mcb.6.7.2716-2720.1986 |
0.32 |
|
| 1986 |
Dandekar S, Sukumar S, Zarbl H, Young LJ, Cardiff RD. Specific activation of the cellular Harvey-ras oncogene in dimethylbenzanthracene-induced mouse mammary tumors. Molecular and Cellular Biology. 6: 4104-8. PMID 3099168 DOI: 10.1128/Mcb.6.11.4104 |
0.35 |
|
| 1986 |
Zarbl H, Sukumar S, Arthur AL, Martin-Zanca D, Barbacid M. Activation of H-ras-1 oncogenes by chemical carcinogens. Basic Life Sciences. 38: 385-97. PMID 3017289 DOI: 10.1007/978-1-4615-9462-8_42 |
0.379 |
|
| 1983 |
Sukumar S, Notario V, Martin-Zanca D, Barbacid M. Induction of mammary carcinomas in rats by nitroso-methylurea involves malignant activation of H-ras-1 locus by single point mutations. Nature. 306: 658-61. PMID 6318112 DOI: 10.1038/306658A0 |
0.303 |
|
| Show low-probability matches. |