David J Brooks - Publications

Affiliations: 
MRC PET Unit Hammersmith Hospital, UK 

335 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Horsager J, Andersen KB, Knudsen K, Skjærbæk C, Fedorova TD, Okkels N, Schaeffer E, Bonkat SK, Geday J, Otto M, Sommerauer M, Danielsen EH, Bech E, Kraft J, Munk OL, ... ... Brooks DJ, et al. Brain-first versus body-first Parkinson's disease: a multimodal imaging case-control study. Brain : a Journal of Neurology. PMID 32830221 DOI: 10.1093/Brain/Awaa238  0.359
2020 Thomsen MB, Jacobsen J, Lillethorup TP, Schacht AC, Simonsen M, Romero-Ramos M, Brooks DJ, Landau AM. In vivo imaging of synaptic SV2A protein density in healthy and striatal-lesioned rats with [11C]UCB-J PET. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X20931140. PMID 32538280 DOI: 10.1177/0271678X20931140  0.315
2020 Andersen KB, Hansen AK, Sommerauer M, Fedorova TD, Knudsen K, Vang K, Van Den Berge N, Kinnerup M, Nahimi A, Pavese N, Brooks DJ, Borghammer P. Altered sensorimotor cortex noradrenergic function in idiopathic REM sleep behaviour disorder - A PET study. Parkinsonism & Related Disorders. 75: 63-69. PMID 32480309 DOI: 10.1016/J.Parkreldis.2020.05.013  0.351
2020 Ismail R, Parbo P, Madsen LS, Hansen AK, Hansen KV, Schaldemose JL, Kjeldsen PL, Stokholm MG, Gottrup H, Eskildsen SF, Brooks DJ. The relationships between neuroinflammation, beta-amyloid and tau deposition in Alzheimer's disease: a longitudinal PET study. Journal of Neuroinflammation. 17: 151. PMID 32375809 DOI: 10.1186/S12974-020-01820-6  0.308
2020 Gersel Stokholm M, Garrido A, Tolosa E, Serradell M, Iranzo A, Østergaard K, Borghammer P, Møller A, Parbo P, Stær K, Brooks DJ, Martí MJ, Pavese N. Imaging dopamine function and microglia in asymptomatic LRRK2 mutation carriers. Journal of Neurology. PMID 32318850 DOI: 10.1007/S00415-020-09830-3  0.349
2020 Parbo P, Madsen LS, Ismail R, Zetterberg H, Blennow K, Eskildsen SF, Vorup-Jensen T, Brooks DJ. Low plasma neurofilament light levels associated with raised cortical microglial activation suggest inflammation acts to protect prodromal Alzheimer's disease. Alzheimer's Research & Therapy. 12: 3. PMID 31898549 DOI: 10.1186/S13195-019-0574-0  0.322
2020 Kacprzak T, Herbel J, Nicola A, Sgier R, Tarsitano F, Bruderer C, Amara A, Refregier A, Bridle SL, Drlica-Wagner A, Gruen D, Hartley WG, Hoyle B, Secco LF, Zuntz J, ... ... Brooks D, et al. Monte Carlo control loops for cosmic shear cosmology with DES Year 1 data Physical Review D. 101: 82003. DOI: 10.1103/Physrevd.101.082003  0.302
2020 Lemon C, Auger MW, McMahon R, Anguita T, Apostolovski Y, Chen GC, Fassnacht CD, Melo AD, Motta V, Shajib A, Treu T, Agnello A, Buckley-Geer E, Schechter PL, Birrer S, ... ... Brooks D, et al. The STRong lensing Insights into the Dark Energy Survey (STRIDES) 2017/2018 follow-up campaign: discovery of 10 lensed quasars and 10 quasar pairs Monthly Notices of the Royal Astronomical Society. 494: 3491-3511. DOI: 10.1093/Mnras/Staa652  0.304
2019 Hansen AK, Parbo P, Ismail R, Østergaard K, Brooks DJ, Borghammer P. Tau Tangles in Parkinson's Disease: A 2-Year Follow-Up Flortaucipir PET Study. Journal of Parkinson's Disease. PMID 31815700 DOI: 10.3233/Jpd-191774  0.381
2019 Pasquini J, Durcan R, Wiblin L, Gersel Stokholm M, Rochester L, Brooks DJ, Burn D, Pavese N. Clinical implications of early caudate dysfunction in Parkinson's disease. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 31079063 DOI: 10.1136/Jnnp-2018-320157  0.336
2019 Ismail R, Parbo P, Hansen KV, Schaldemose JL, Dalby RB, Tietze A, Kjeldsen PL, la Cour SH, Qvist P, Gottrup H, Eskildsen SF, Brooks DJ. Abnormal Amyloid Load in Mild Cognitive Impairment: The Effect of Reducing the PiB-PET Threshold. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. PMID 31074062 DOI: 10.1111/Jon.12629  0.303
2019 Pasquini J, Ceravolo R, Brooks DJ, Bonuccelli U, Pavese N. Progressive loss of raphe nuclei serotonin transporter in early Parkinson's disease: A longitudinal I-FP-CIT SPECT study. Parkinsonism & Related Disorders. PMID 30981664 DOI: 10.1016/J.Parkreldis.2019.03.025  0.311
2019 Schubert JJ, Veronese M, Marchitelli L, Bodini B, Tonietto M, Stankoff B, Brooks DJ, Bertoldo A, Edison P, Turkheimer F. Dynamic C-PiB PET shows cerebrospinal fluid flow alterations in Alzheimer's disease and multiple sclerosis. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 30850505 DOI: 10.2967/Jnumed.118.223834  0.339
2019 Baxter EJ, Omori Y, Chang C, Giannantonio T, Kirk D, Krause E, Blazek J, Bleem L, Choi A, Crawford TM, Dodelson S, Eifler TF, Friedrich O, Gruen D, Holder GP, ... ... Brooks D, et al. Dark Energy Survey Year 1 results: Methodology and projections for joint analysis of galaxy clustering, galaxy lensing, and CMB lensing two-point functions Physical Review D. 99: 23508. DOI: 10.1103/Physrevd.99.023508  0.308
2019 Abbott TMC, Abdalla FB, Alarcon A, Allam S, Annis J, Avila S, Aylor K, Banerji M, Banik N, Baxter EJ, Bechtol K, Becker MR, Benson BA, Bernstein GM, Bertin E, ... ... Brooks D, et al. Dark Energy Survey Year 1 Results: Joint Analysis of Galaxy Clustering, Galaxy Lensing, and CMB Lensing Two-point Functions Physical Review D. 100: 23541. DOI: 10.1103/Physrevd.100.023541  0.302
2019 Camacho H, Kokron N, Andrade-Oliveira F, Rosenfeld R, Lima M, Lacasa F, Sobreira F, Costa LNd, Avila S, Chan KC, Crocce M, Ross AJ, Troja A, García-Bellido J, Abbott TMC, ... ... Brooks D, et al. Dark Energy Survey Year 1 results: measurement of the galaxy angular power spectrum Monthly Notices of the Royal Astronomical Society. 487: 3870-3883. DOI: 10.1093/Mnras/Stz1514  0.304
2019 Venkataraman AV, Mansur A, Lewis Y, Kocagoncu E, Lingford-Hughes A, Huiban M, Passchier J, Rowe JB, Tsukada H, Brooks DJ, Gunn RN, Matthews PM, Rabiner EA, Consortium M. P2-366: QUANTIFYING MITOCHONDRIAL AND SYNAPTIC FUNCTION IN ALZHEIMER'S DISEASE USING [18 F]BCPP-EF, [11 C]SA4503 AND [11 C]UCB-J PET IMAGING Alzheimer's & Dementia. 15: P740-P741. DOI: 10.1016/J.Jalz.2019.06.2773  0.312
2018 Helmich RC, Vaillancourt DE, Brooks DJ. The Future of Brain Imaging in Parkinson's Disease. Journal of Parkinson's Disease. 8: S47-S51. PMID 30584163 DOI: 10.3233/Jpd-181482  0.32
2018 Dani M, Wood M, Mizoguchi R, Fan Z, Walker Z, Morgan R, Hinz R, Biju M, Kuruvilla T, Brooks DJ, Edison P. Microglial activation correlates in vivo with both tau and amyloid in Alzheimer's disease. Brain : a Journal of Neurology. PMID 30052812 DOI: 10.1093/Brain/Awy188  0.34
2018 Pinholt Lillethorup T, Glud AN, Landeck N, Alstrup AKO, Jakobsen S, Vang K, Doudet DJ, Brooks DJ, Kirik D, Hinz R, Sørensen JC, Landau AM. In vivo Quantification of Glial Activation in Minipigs Overexpressing human α-synuclein. Synapse (New York, N.Y.). PMID 30009467 DOI: 10.1002/Syn.22060  0.311
2018 Parbo P, Ismail R, Sommerauer M, Stokholm MG, Hansen AK, Hansen KV, Amidi A, Schaldemose JL, Gottrup H, Brændgaard H, Eskildsen SF, Borghammer P, Hinz R, Aanerud J, Brooks DJ. Does inflammation precede tau aggregation in early Alzheimer's disease? A PET study. Neurobiology of Disease. PMID 29902557 DOI: 10.1016/J.Nbd.2018.06.004  0.316
2018 Edison P, Brooks DJ. Role of Neuroinflammation in the Trajectory of Alzheimer's Disease and in vivo Quantification Using PET. Journal of Alzheimer's Disease : Jad. PMID 29865053 DOI: 10.3233/Jad-179929  0.314
2018 Sommerauer M, Hansen AK, Parbo P, Fedorova TD, Knudsen K, Frederiksen Y, Nahimi A, Barbe MT, Brooks DJ, Borghammer P. Decreased noradrenaline transporter density in the motor cortex of Parkinson's disease patients. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 29797351 DOI: 10.1002/Mds.27411  0.351
2018 Minett T, Su L, Mak E, Williams G, Firbank M, Lawson RA, Yarnall AJ, Duncan GW, Owen AM, Khoo TK, Brooks DJ, Rowe JB, Barker RA, Burn D, O'Brien JT. Longitudinal diffusion tensor imaging changes in early Parkinson's disease: ICICLE-PD study. Journal of Neurology. PMID 29696499 DOI: 10.1007/S00415-018-8873-0  0.315
2018 Lillethorup TP, Glud AN, Alstrup AKO, Mikkelsen TW, Nielsen EH, Zaer H, Doudet DJ, Brooks DJ, Sørensen JCH, Orlowski D, Landau AM. Nigrostriatal proteasome inhibition impairs dopamine neurotransmission and motor function in minipigs. Experimental Neurology. PMID 29428213 DOI: 10.1016/J.Expneurol.2018.02.005  0.343
2018 Pasquini J, Ceravolo R, Qamhawi Z, Lee JY, Deuschl G, Brooks DJ, Bonuccelli U, Pavese N. Progression of tremor in early stages of Parkinson's disease: a clinical and neuroimaging study. Brain : a Journal of Neurology. PMID 29365117 DOI: 10.1093/Brain/Awx376  0.346
2018 Abbott TMC, Abdalla FB, Allam S, Amara A, Annis J, Asorey J, Avila S, Ballester O, Banerji M, Barkhouse W, Baruah L, Baumer M, Bechtol K, Becker MR, Benoit-Lévy A, ... ... Brooks D, et al. The Dark Energy Survey: Data Release 1 Astrophysical Journal Supplement Series. 239: 18-18. DOI: 10.3847/1538-4365/Aae9F0  0.301
2018 Drlica-Wagner A, Sevilla-Noarbe I, Rykoff ES, Gruendl RA, Yanny B, Tucker DL, Hoyle B, Rosell AC, Bernstein GM, Bechtol K, Becker MR, Benoit-Lévy A, Bertin E, Kind MC, Davis C, ... ... Brooks D, et al. Dark Energy Survey Year 1 Results: The Photometric Data Set for Cosmology Astrophysical Journal Supplement Series. 235: 33. DOI: 10.3847/1538-4365/Aab4F5  0.301
2018 Abbott TMC, Abdalla FB, Alarcon A, Aleksić J, Allam S, Allen S, Amara A, Annis J, Asorey J, Avila S, Bacon D, Balbinot E, Banerji M, Banik N, Barkhouse W, ... ... Brooks D, et al. Dark Energy Survey year 1 results: Cosmological constraints from galaxy clustering and weak lensing Physical Review D. 98: 43526. DOI: 10.1103/Physrevd.98.043526  0.317
2018 Wethers CF, Banerji M, Hewett PC, Lemon CA, McMahon RG, Reed SL, Shen Y, Abdalla FB, Benoit-Lévy A, Brooks D, Buckley-Geer E, Capozzi D, Carnero Rosell A, CarrascoKind M, Carretero J, et al. UV-luminous, star-forming hosts of z ∼ 2 reddened quasars in the Dark Energy Survey Monthly Notices of the Royal Astronomical Society. 475: 3682-3699. DOI: 10.1093/Mnras/Stx3332  0.3
2017 Sommerauer M, Fedorova TD, Hansen AK, Knudsen K, Otto M, Jeppesen J, Frederiksen Y, Blicher JU, Geday J, Nahimi A, Damholdt MF, Brooks DJ, Borghammer P. Evaluation of the noradrenergic system in Parkinson's disease: an 11C-MeNER PET and neuromelanin MRI study. Brain : a Journal of Neurology. PMID 29272343 DOI: 10.1093/Brain/Awx348  0.363
2017 Obeso JA, Stamelou M, Goetz CG, Poewe W, Lang AE, Weintraub D, Burn D, Halliday GM, Bezard E, Przedborski S, Lehericy S, Brooks DJ, Rothwell JC, Hallett M, DeLong MR, et al. Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy. Movement Disorders : Official Journal of the Movement Disorder Society. 32: 1264-1310. PMID 28887905 DOI: 10.1002/Mds.27115  0.315
2017 Politis M, Wilson H, Wu K, Brooks DJ, Piccini P. Chronic exposure to dopamine agonists affects the integrity of striatal D2 receptors in Parkinson's patients. Neuroimage. Clinical. 16: 455-460. PMID 28879087 DOI: 10.1016/J.Nicl.2017.08.013  0.349
2017 Borghammer P, Knudsen K, Fedorova TD, Brooks DJ. Imaging Parkinson's disease below the neck. Npj Parkinson's Disease. 3: 15. PMID 28649615 DOI: 10.1038/S41531-017-0017-1  0.322
2017 Parbo P, Ismail R, Hansen KV, Amidi A, Mårup FH, Gottrup H, Brændgaard H, Eriksson BO, Eskildsen SF, Lund TE, Tietze A, Edison P, Pavese N, Stokholm MG, Borghammer P, ... ... Brooks DJ, et al. Brain inflammation accompanies amyloid in the majority of mild cognitive impairment cases due to Alzheimer's disease. Brain : a Journal of Neurology. PMID 28575151 DOI: 10.1093/Brain/Awx120  0.308
2017 Mak E, Su L, Williams GB, Firbank MJ, Lawson RA, Yarnall AJ, Duncan GW, Mollenhauer B, Owen AM, Khoo TK, Brooks DJ, Rowe JB, Barker RA, Burn DJ, O'Brien JT. Longitudinal whole-brain atrophy and ventricular enlargement in nondemented Parkinson's disease. Neurobiology of Aging. 55: 78-90. PMID 28431288 DOI: 10.1016/J.Neurobiolaging.2017.03.012  0.304
2017 Firbank MJ, Yarnall AJ, Lawson RA, Duncan GW, Khoo TK, Petrides GS, O'Brien JT, Barker RA, Maxwell RJ, Brooks DJ, Burn DJ. Cerebral glucose metabolism and cognition in newly diagnosed Parkinson's disease: ICICLE-PD study. Journal of Neurology, Neurosurgery, and Psychiatry. 88: 310-316. PMID 28315844 DOI: 10.1136/Jnnp-2016-313918  0.339
2017 Hansen AK, Damholdt MF, Fedorova TD, Knudsen K, Parbo P, Ismail R, Østergaard K, Brooks DJ, Borghammer P. In Vivo cortical tau in Parkinson's disease using 18F-AV-1451 positron emission tomography. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 28256006 DOI: 10.1002/Mds.26961  0.341
2017 Fan Z, Brooks DJ, Okello A, Edison P. An early and late peak in microglial activation in Alzheimer's disease trajectory. Brain : a Journal of Neurology. PMID 28122877 DOI: 10.1093/Brain/Aww349  0.317
2017 Fedorova TD, Seidelin LB, Knudsen K, Schacht AC, Geday J, Pavese N, Brooks DJ, Borghammer P. Decreased intestinal acetylcholinesterase in early Parkinson disease: An 11C-donepezil PET study. Neurology. PMID 28100726 DOI: 10.1212/Wnl.0000000000003633  0.344
2017 Peraza LR, Nesbitt D, Lawson RA, Duncan GW, Yarnall AJ, Khoo TK, Kaiser M, Firbank MJ, O'Brien JT, Barker RA, Brooks DJ, Burn DJ, Taylor JP. Intra- and inter-network functional alterations in Parkinson's disease with mild cognitive impairment. Human Brain Mapping. PMID 28084651 DOI: 10.1002/Hbm.23499  0.306
2017 Albert A, Anderson B, Bechtol K, Drlica-Wagner A, Meyer M, Sánchez-Conde M, Strigari L, Wood M, Abbott TMC, Abdalla FB, Benoit-Lévy A, Bernstein GM, Bernstein RA, Bertin E, Brooks D, et al. Searching for Dark Matter Annihilation in Recently Discovered Milky Way Satellites with Fermi-LAT The Astrophysical Journal. 834: 110. DOI: 10.3847/1538-4357/834/2/110  0.301
2017 Reed SL, McMahon RG, Martini P, Banerji M, Auger M, Hewett PC, Koposov SE, Gibbons SLJ, Gonzalez-Solares E, Ostrovski F, Tie SS, Abdalla FB, Allam S, Benoit-Lévy A, Bertin E, ... Brooks D, et al. Eight new luminous z ≥ 6 quasars discovered via SED model fitting of VISTA, WISE and Dark Energy Survey Year 1 observations Monthly Notices of the Royal Astronomical Society. 468: 4702-4718. DOI: 10.1093/Mnras/Stx728  0.302
2017 Samuroff S, Bridle SL, Zuntz J, Troxel MA, Gruen D, Rollins RP, Bernstein GM, Eifler TF, Huff EM, Kacprzak T, Krause E, MacCrann N, Abdalla FB, Allam S, Annis J, ... ... Brooks D, et al. Dark Energy Survey Year 1 results: the impact of galaxy neighbours on weak lensing cosmology with im3shape Monthly Notices of the Royal Astronomical Society. 475: 4524-4543. DOI: 10.1093/Mnras/Stx3282  0.302
2017 Jouvel S, Delubac T, Comparat J, Camacho H, Carnero A, Abdalla FB, Kneib J, Merson A, Lima M, Sobreira F, da Costa L, Prada F, Zhu GB, Benoit-Levy A, Macora ADL, ... ... Brooks D, et al. Photometric redshifts and clustering of emission line galaxies selected jointly by DES and eBOSS Monthly Notices of the Royal Astronomical Society. 469: 2771-2790. DOI: 10.1093/Mnras/Stx163  0.3
2016 Politis M, Sauerbier A, Loane C, Pavese N, Martin A, Corcoran B, Brooks DJ, Ray-Chaudhuri K, Piccini P. Sustained striatal dopamine levels following intestinal levodopa infusions in Parkinson's disease patients. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 27859651 DOI: 10.1002/Mds.26848  0.316
2016 Brooks DJ. Imaging of genetic and degenerative disorders primarily causing Parkinsonism. Handbook of Clinical Neurology. 135: 493-505. PMID 27432680 DOI: 10.1016/B978-0-444-53485-9.00024-6  0.301
2016 Feeney C, Scott G, Raffel J, Roberts S, Coello C, Jolly A, Searle G, Goldstone AP, Brooks DJ, Nicholas RS, Trigg W, Gunn RN, Sharp DJ. Kinetic analysis of the translocator protein positron emission tomography ligand [(18)F]GE-180 in the human brain. European Journal of Nuclear Medicine and Molecular Imaging. PMID 27349244 DOI: 10.1007/S00259-016-3444-Z  0.31
2016 Fan Z, Calsolaro V, Atkinson RÁ, Femminella GD, Waldman A, Buckley C, Trigg W, Brooks DJ, Hinz R, Edison P. Flutriciclamide (18F-GE180) PET: first in human PET study of novel 3rd generation in vivo marker of human translator protein. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 27261523 DOI: 10.2967/Jnumed.115.169078  0.312
2016 Hansen AK, Knudsen K, Lillethorup TP, Landau AM, Parbo P, Fedorova T, Audrain H, Bender D, Østergaard K, Brooks DJ, Borghammer P. In vivo imaging of neuromelanin in Parkinson's disease using 18F-AV-1451 PET. Brain : a Journal of Neurology. PMID 27190023 DOI: 10.1093/Brain/Aww098  0.377
2016 Borghammer P, Knudsen K, Brooks DJ. Imaging Systemic Dysfunction in Parkinson's Disease. Current Neurology and Neuroscience Reports. 16: 51. PMID 27072951 DOI: 10.1007/S11910-016-0655-4  0.313
2016 Taylor S, Gafton J, Shah B, Pagano G, Chaudhuri KR, Brooks DJ, Pavese N. Progression of nonmotor symptoms in subgroups of patients with non-dopamine-deficient Parkinsonism. Movement Disorders : Official Journal of the Movement Disorder Society. 31: 344-51. PMID 26863920 DOI: 10.1002/Mds.26456  0.325
2016 Brooks DJ. Molecular Imaging of Dopamine Transporters. Ageing Research Reviews. PMID 26802555 DOI: 10.1016/J.Arr.2015.12.009  0.34
2016 Dani M, Edison P, Brooks DJ. Imaging biomarkers in tauopathies. Parkinsonism & Related Disorders. 22: S26-8. PMID 26299160 DOI: 10.1016/J.Parkreldis.2015.08.011  0.33
2016 Suchyta E, Huff EM, Aleksić J, Melchior P, Jouvel S, MacCrann N, Ross AJ, Crocce M, Gaztanaga E, Honscheid K, Leistedt B, Peiris HV, Rykoff ES, Sheldon E, Abbott T, ... ... Brooks D, et al. No galaxy left behind: Accurate measurements with the faintest objects in the Dark Energy Survey Monthly Notices of the Royal Astronomical Society. 457: 786-808. DOI: 10.1093/Mnras/Stv2953  0.307
2016 Fan Z, Brooks DJ, Okello A, Edison P. An Early And Late Peak In Microglial Activation In Alzheimer’S Disease Trajectory: A Longitudinal Pet Study Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.1033  0.314
2016 Dani M, Brooks DJ, Edison P. Tau imaging in neurodegenerative diseases European Journal of Nuclear Medicine and Molecular Imaging. 43: 1139-1150. DOI: 10.1007/S00259-015-3231-2  0.313
2015 Fan Z, Okello AA, Brooks DJ, Edison P. Longitudinal influence of microglial activation and amyloid on neuronal function in Alzheimer's disease. Brain : a Journal of Neurology. PMID 26510952 DOI: 10.1093/Brain/Awv288  0.345
2015 Qamhawi Z, Towey D, Shah B, Pagano G, Seibyl J, Marek K, Borghammer P, Brooks DJ, Pavese N. Clinical correlates of raphe serotonergic dysfunction in early Parkinson's disease. Brain. 138: 2964-2973. PMID 26209314 DOI: 10.1093/Brain/Awv215  0.33
2015 Duncan GW, Firbank MJ, Yarnall AJ, Khoo TK, Brooks DJ, Barker RA, Burn DJ, O'Brien JT. Gray and white matter imaging: A biomarker for cognitive impairment in early Parkinson's disease? Movement Disorders : Official Journal of the Movement Disorder Society. PMID 26202802 DOI: 10.1002/Mds.26312  0.32
2015 Mak E, Su L, Williams GB, Firbank MJ, Lawson RA, Yarnall AJ, Duncan GW, Owen AM, Khoo TK, Brooks DJ, Rowe JB, Barker RA, Burn DJ, O'Brien JT. Baseline and longitudinal grey matter changes in newly diagnosed Parkinson's disease: ICICLE-PD study. Brain : a Journal of Neurology. PMID 26173861 DOI: 10.1093/Brain/Awv211  0.327
2015 McGinnity CJ, Koepp MJ, Hammers A, Riaño Barros DA, Pressler RM, Luthra S, Jones PA, Trigg W, Micallef C, Symms MR, Brooks DJ, Duncan JS. NMDA receptor binding in focal epilepsies. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 25991402 DOI: 10.1136/Jnnp-2014-309897  0.308
2015 Brooks DJ. Neuroimaging in Parkinson's disease: a future perspective. Neurodegenerative Disease Management. 5: 105-8. PMID 25894874 DOI: 10.2217/Nmt.14.56  0.303
2015 Senda M, Yamamoto Y, Sasaki M, Yamane T, Brooks DJ, Farrar G, McParland B, Heurling K. An exploratory efficacy study of the amyloid imaging agent [(18)F]flutemetamol in Japanese Subjects. Annals of Nuclear Medicine. 29: 391-9. PMID 25874747 DOI: 10.1007/S12149-015-0957-7  0.315
2015 Smith R, Wu K, Hart T, Loane C, Brooks DJ, Björklund A, Odin P, Piccini P, Politis M. The role of pallidal serotonergic function in Parkinson's disease dyskinesias: a positron emission tomography study. Neurobiology of Aging. 36: 1736-42. PMID 25649022 DOI: 10.1016/J.Neurobiolaging.2014.12.037  0.35
2015 Gjerløff T, Fedorova T, Knudsen K, Munk OL, Nahimi A, Jacobsen S, Danielsen EH, Terkelsen AJ, Hansen J, Pavese N, Brooks DJ, Borghammer P. Imaging acetylcholinesterase density in peripheral organs in Parkinson's disease with 11C-donepezil PET. Brain : a Journal of Neurology. 138: 653-63. PMID 25539902 DOI: 10.1093/Brain/Awu369  0.366
2015 Varley J, Brooks DJ, Edison P. Imaging neuroinflammation in Alzheimer's disease and other dementias: Recent advances and future directions. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 1110-20. PMID 25449529 DOI: 10.1016/J.Jalz.2014.08.105  0.325
2015 Fan Z, Aman Y, Ahmed I, Chetelat G, Landeau B, Ray Chaudhuri K, Brooks DJ, Edison P. Influence of microglial activation on neuronal function in Alzheimer's and Parkinson's disease dementia. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 608-621.e7. PMID 25239737 DOI: 10.1016/J.Jalz.2014.06.016  0.35
2015 Yuan F, Lidman C, Davis TM, Childress M, Abdalla FB, Banerji M, Buckley-Geer E, Carnero Rosell A, Carollo D, Castander FJ, D'Andrea CB, Diehl HT, Cunha CE, Foley RJ, Frieman J, ... ... Brooks D, et al. OzDES multifibre spectroscopy for the Dark Energy Survey: First-year operation and results Monthly Notices of the Royal Astronomical Society. 452: 3047-3063. DOI: 10.1093/Mnras/Stv1507  0.303
2015 Drlica-Wagner A, Bechtol K, Rykoff ES, Luque E, Queiroz A, Mao YY, Wechsler RH, Simon JD, Santiago B, Yanny B, Balbinot E, Dodelson S, Neto AF, James DJ, Li TS, ... ... Brooks D, et al. EIGHT ULTRA-FAINT GALAXY CANDIDATES DISCOVERED in YEAR TWO of the DARK ENERGY SURVEY Astrophysical Journal. 813. DOI: 10.1088/0004-637X/813/2/109  0.3
2015 Kessler R, Marriner J, Childress M, Covarrubias R, D'Andrea CB, Finley DA, Fischer J, Foley RJ, Goldstein D, Gupta RR, Kuehn K, Marcha M, Nichol RC, Papadopoulos A, Sako M, ... ... Brooks D, et al. THE DIFFERENCE IMAGING PIPELINE for the TRANSIENT SEARCH in the DARK ENERGY SURVEY Astronomical Journal. 150. DOI: 10.1088/0004-6256/150/6/172  0.304
2015 Calsolaro V, Fan Z, Brooks DJ, Edison P. Role of neuroinflammation in Alzheimer’s and parkinson’s disease: [11C]PK11195 PET study Alzheimers & Dementia. 11: 792. DOI: 10.1016/J.Jalz.2015.06.1770  0.32
2014 Gjerløff T, Jakobsen S, Nahimi A, Munk OL, Bender D, Alstrup AK, Vase KH, Hansen SB, Brooks DJ, Borghammer P. In vivo imaging of human acetylcholinesterase density in peripheral organs using 11C-donepezil: dosimetry, biodistribution, and kinetic analyses. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 55: 1818-24. PMID 25324520 DOI: 10.2967/Jnumed.114.143859  0.319
2014 Nombela C, Rowe JB, Winder-Rhodes SE, Hampshire A, Owen AM, Breen DP, Duncan GW, Khoo TK, Yarnall AJ, Firbank MJ, Chinnery PF, Robbins TW, O'Brien JT, Brooks DJ, Burn DJ, et al. Genetic impact on cognition and brain function in newly diagnosed Parkinson's disease: ICICLE-PD study. Brain : a Journal of Neurology. 137: 2743-58. PMID 25080285 DOI: 10.1093/Brain/Awu201  0.327
2014 Mollenhauer B, Rochester L, Chen-Plotkin A, Brooks D. What can biomarkers tell us about cognition in Parkinson's disease? Movement Disorders. 29: 622-633. PMID 24757111 DOI: 10.1002/Mds.25846  0.302
2014 Politis M, Wu K, Loane C, Brooks DJ, Kiferle L, Turkheimer FE, Bain P, Molloy S, Piccini P. Serotonergic mechanisms responsible for levodopa-induced dyskinesias in Parkinson's disease patients. The Journal of Clinical Investigation. 124: 1340-9. PMID 24531549 DOI: 10.1172/Jci71640  0.33
2013 Cenci MA, Brooks DJ. Bad news for neuroprotective therapies in PD? Journal of Parkinson's Disease. 3: 271-3. PMID 24018335 DOI: 10.3233/Jpd-139001  0.328
2013 Patel NK, Pavese N, Javed S, Hotton GR, Brooks DJ, Gill SS. Benefits of putaminal GDNF infusion in Parkinson disease are maintained after GDNF cessation. Neurology. 81: 1176-8. PMID 23946313 DOI: 10.1212/Wnl.0B013E3182A55Ea5  0.355
2013 Ikoma Y, Edison P, Ramlackhansingh A, Brooks DJ, Turkheimer FE. Reference region automatic extraction in dynamic [(11)C]PIB. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 33: 1725-31. PMID 23921900 DOI: 10.1038/Jcbfm.2013.133  0.313
2013 Loane C, Wu K, Bain P, Brooks DJ, Piccini P, Politis M. Serotonergic loss in motor circuitries correlates with severity of action-postural tremor in PD. Neurology. 80: 1850-5. PMID 23596065 DOI: 10.1212/Wnl.0B013E318292A31D  0.302
2013 Lawrence AD, Brooks DJ, Whone AL. Ventral striatal dopamine synthesis capacity predicts financial extravagance in Parkinson's disease. Frontiers in Psychology. 4: 90. PMID 23450713 DOI: 10.3389/Fpsyg.2013.00090  0.323
2013 Kobylecki C, Counsell SJ, Cabanel N, Wächter T, Turkheimer FE, Eggert K, Oertel W, Brooks DJ, Gerhard A. Diffusion-weighted imaging and its relationship to microglial activation in parkinsonian syndromes. Parkinsonism & Related Disorders. 19: 527-32. PMID 23425503 DOI: 10.1016/J.Parkreldis.2013.01.017  0.329
2013 Khoo TK, Yarnall AJ, Duncan GW, Coleman S, O'Brien JT, Brooks DJ, Barker RA, Burn DJ. The spectrum of nonmotor symptoms in early Parkinson disease. Neurology. 80: 276-81. PMID 23319473 DOI: 10.1212/Wnl.0B013E31827Deb74  0.3
2013 Edison P, Ahmed I, Fan Z, Hinz R, Gelosa G, Ray Chaudhuri K, Walker Z, Turkheimer FE, Brooks DJ. Microglia, amyloid, and glucose metabolism in Parkinson's disease with and without dementia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 938-49. PMID 23303049 DOI: 10.1038/Npp.2012.255  0.366
2013 Berardelli A, Wenning GK, Antonini A, Berg D, Bloem BR, Bonifati V, Brooks D, Burn DJ, Colosimo C, Fanciulli A, Ferreira J, Gasser T, Grandas F, Kanovsky P, Kostic V, et al. EFNS/MDS-ES/ENS [corrected] recommendations for the diagnosis of Parkinson's disease. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 20: 16-34. PMID 23279440 DOI: 10.1111/Ene.12022  0.311
2013 Edison P, Carter SF, Rinne JO, Gelosa G, Herholz K, Nordberg A, Brooks DJ, Hinz R. Comparison of MRI based and PET template based approaches in the quantitative analysis of amyloid imaging with PIB-PET. Neuroimage. 70: 423-33. PMID 23261639 DOI: 10.1016/J.Neuroimage.2012.12.014  0.337
2013 Nordberg A, Carter SF, Rinne J, Drzezga A, Brooks DJ, Vandenberghe R, Perani D, Forsberg A, LÃ¥ngström B, Scheinin N, Karrasch M, NÃ¥gren K, Grimmer T, Miederer I, Edison P, et al. A European multicentre PET study of fibrillar amyloid in Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging. 40: 104-14. PMID 22961445 DOI: 10.1007/S00259-012-2237-2  0.306
2012 Wu K, O'Keeffe D, Politis M, O'Keeffe GC, Robbins TW, Bose SK, Brooks DJ, Piccini P, Barker RA. The catechol-O-methyltransferase Val(158)Met polymorphism modulates fronto-cortical dopamine turnover in early Parkinson's disease: a PET study. Brain : a Journal of Neurology. 135: 2449-57. PMID 22843413 DOI: 10.1093/Brain/Aws157  0.368
2012 Politis M, Wu K, Loane C, Quinn NP, Brooks DJ, Oertel WH, Björklund A, Lindvall O, Piccini P. Serotonin neuron loss and nonmotor symptoms continue in Parkinson's patients treated with dopamine grafts. Science Translational Medicine. 4: 128ra41. PMID 22491951 DOI: 10.1126/Scitranslmed.3003391  0.336
2012 Gelosa G, Brooks DJ. The prognostic value of amyloid imaging. European Journal of Nuclear Medicine and Molecular Imaging. 39: 1207-19. PMID 22491780 DOI: 10.1007/S00259-012-2108-X  0.311
2012 Edison P, Hinz R, Ramlackhansingh AF, Thomas J, Gelosa G, Archer HA, Turkheimer FE, Brooks DJ. Can target-to-pons ratio be used as a reliable method for the analysis of [ 11C]PIB brain scans? Neuroimage. 60: 1716-1723. PMID 22306804 DOI: 10.1016/J.Neuroimage.2012.01.099  0.317
2012 Thurfjell L, Lötjönen J, Lundqvist R, Koikkalainen J, Soininen H, Waldemar G, Brooks DJ, Vandenberghe R. Combination of biomarkers: PET [18F]flutemetamol imaging and structural MRI in dementia and mild cognitive impairment. Neuro-Degenerative Diseases. 10: 246-9. PMID 22301718 DOI: 10.1159/000335381  0.302
2012 Lewis SJ, Pavese N, Rivero-Bosch M, Eggert K, Oertel W, Mathias CJ, Brooks DJ, Gerhard A. Brain monoamine systems in multiple system atrophy: a positron emission tomography study. Neurobiology of Disease. 46: 130-6. PMID 22266105 DOI: 10.1016/J.Nbd.2011.12.053  0.367
2012 Brooks DJ. Can imaging separate multiple system atrophy from Parkinson's disease? Movement Disorders : Official Journal of the Movement Disorder Society. 27: 3-5. PMID 22252889 DOI: 10.1002/Mds.24046  0.306
2012 Brooks DJ. Parkinson's disease: diagnosis. Parkinsonism & Related Disorders. 18: S31-3. PMID 22166447 DOI: 10.1016/S1353-8020(11)70012-8  0.333
2012 Pavese N, Simpson BS, Metta V, Ramlackhansingh A, Chaudhuri KR, Brooks DJ. [¹⁸F]FDOPA uptake in the raphe nuclei complex reflects serotonin transporter availability. A combined [¹⁸F]FDOPA and [¹¹C]DASB PET study in Parkinson's disease. Neuroimage. 59: 1080-4. PMID 21963917 DOI: 10.1016/J.Neuroimage.2011.09.034  0.357
2012 Hyare H, Ramlackhansingh A, Gelosa G, Edison P, Rudge P, Brandner S, Brooks DJ, Collinge J, Mead S. 11C-PiB PET does not detect PrP-amyloid in prion disease patients including variant Creutzfeldt-Jakob disease. Journal of Neurology, Neurosurgery, and Psychiatry. 83: 340-1. PMID 21478204 DOI: 10.1136/Jnnp.2010.233692  0.332
2012 Tai Y, Pavese N, Tabrizi S, Barker R, Brooks D, Piccini P. 2.039 LONGITUDINAL PET STUDIES OF MICROGLIAL ACTIVATION IN HUNTINGTON'S DISEASE Parkinsonism & Related Disorders. 18: S101. DOI: 10.1016/S1353-8020(11)70472-2  0.331
2012 Simpson B, Ramlackhansingh A, Pavese N, Barker R, Breen D, Brooks D. 2.026 INCREASED MICROGLIAL ACTIVATION AND AMYLOID DEPOSITION IN PARKINSON'S DISEASE SUBJECTS AT HIGH RISK OF DEMENTIA: A PET STUDY Parkinsonism & Related Disorders. 18: S97. DOI: 10.1016/S1353-8020(11)70459-X  0.323
2012 Pavese N, Metta V, Simpson BS, Marphy TA, Ramlackhansingh A, Chaudhuri KR, Brooks DJ. 1.060 Sleep Regulatory Centres Dysfunction In Parkinson'S Disease Patients With Excessive Daytime Sleepiness. An In Vivo Pet Study Parkinsonism & Related Disorders. 18. DOI: 10.1016/S1353-8020(11)70174-2  0.304
2011 Marek K, Jennings D, Lasch S, Siderowf A, Tanner C, Simuni T, Coffey C, Kieburtz K, Flagg E, Chowdhury S, Poewe W, Mollenhauer B, Sherer T, Frasier M, Meunier C, ... ... Brooks D, et al. The Parkinson Progression Marker Initiative (PPMI) Progress in Neurobiology. 95: 629-635. PMID 21930184 DOI: 10.1016/J.Pneurobio.2011.09.005  0.304
2011 Brooks DJ, Pavese N. Imaging biomarkers in Parkinson's disease. Progress in Neurobiology. 95: 614-28. PMID 21896306 DOI: 10.1016/J.Pneurobio.2011.08.009  0.375
2011 Stoessl AJ, Brooks DJ, Eidelberg D. Milestones in neuroimaging. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 868-978. PMID 21626537 DOI: 10.1002/Mds.23679  0.329
2011 Politis M, Loane C, Wu K, Brooks DJ, Piccini P. Serotonergic mediated body mass index changes in Parkinson's disease. Neurobiology of Disease. 43: 609-15. PMID 21624463 DOI: 10.1016/J.Nbd.2011.05.009  0.316
2011 Politis M, Oertel WH, Wu K, Quinn NP, Pogarell O, Brooks DJ, Bjorklund A, Lindvall O, Piccini P. Graft-induced dyskinesias in Parkinson's disease: High striatal serotonin/dopamine transporter ratio. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 1997-2003. PMID 21611977 DOI: 10.1002/Mds.23743  0.314
2011 Ramlackhansingh AF, Bose SK, Ahmed I, Turkheimer FE, Pavese N, Brooks DJ. Adenosine 2A receptor availability in dyskinetic and nondyskinetic patients with Parkinson disease. Neurology. 76: 1811-6. PMID 21606452 DOI: 10.1212/Wnl.0B013E31821Ccce4  0.34
2011 Lawrence AD, Goerendt IK, Brooks DJ. Apathy blunts neural response to money in Parkinson's disease. Social Neuroscience. 6: 653-62. PMID 21400357 DOI: 10.1080/17470919.2011.556821  0.3
2011 Pavese N, Rivero-Bosch M, Lewis SJ, Whone AL, Brooks DJ. Progression of monoaminergic dysfunction in Parkinson's disease: a longitudinal 18F-dopa PET study. Neuroimage. 56: 1463-8. PMID 21396455 DOI: 10.1016/J.Neuroimage.2011.03.012  0.369
2011 Ahmed I, Bose SK, Pavese N, Ramlackhansingh A, Turkheimer F, Hotton G, Hammers A, Brooks DJ. Glutamate NMDA receptor dysregulation in Parkinson's disease with dyskinesias. Brain : a Journal of Neurology. 134: 979-86. PMID 21371994 DOI: 10.1093/Brain/Awr028  0.329
2011 Politis M, Pavese N, Tai YF, Kiferle L, Mason SL, Brooks DJ, Tabrizi SJ, Barker RA, Piccini P. Microglial activation in regions related to cognitive function predicts disease onset in Huntington's disease: a multimodal imaging study. Human Brain Mapping. 32: 258-70. PMID 21229614 DOI: 10.1002/Hbm.21008  0.341
2010 Brooks DJ. Imaging dopamine transporters in Parkinson's disease. Biomarkers in Medicine. 4: 651-60. PMID 20945978 DOI: 10.2217/Bmm.10.86  0.344
2010 Brooks DJ, Pavese N. Imaging non-motor aspects of Parkinson's disease. Progress in Brain Research. 184: 205-18. PMID 20887877 DOI: 10.1016/S0079-6123(10)84011-7  0.321
2010 Pavese N, Metta V, Bose SK, Chaudhuri KR, Brooks DJ. Fatigue in Parkinson's disease is linked to striatal and limbic serotonergic dysfunction. Brain : a Journal of Neurology. 133: 3434-43. PMID 20884645 DOI: 10.1093/Brain/Awq268  0.339
2010 Vandenberghe R, Van Laere K, Ivanoiu A, Salmon E, Bastin C, Triau E, Hasselbalch S, Law I, Andersen A, Korner A, Minthon L, Garraux G, Nelissen N, Bormans G, Buckley C, ... ... Brooks DJ, et al. 18F-flutemetamol amyloid imaging in Alzheimer disease and mild cognitive impairment: a phase 2 trial. Annals of Neurology. 68: 319-29. PMID 20687209 DOI: 10.1002/Ana.22068  0.315
2010 Politis M, Wu K, Loane C, Kiferle L, Molloy S, Brooks DJ, Piccini P. Staging of serotonergic dysfunction in Parkinson's Disease: An in vivo 11C-DASB PET study Neurobiology of Disease. 40: 216-221. PMID 20594979 DOI: 10.1016/J.Nbd.2010.05.028  0.347
2010 Brooks DJ. Imaging Approaches to Parkinson Disease The Journal of Nuclear Medicine. 51: 596-609. PMID 20351351 DOI: 10.2967/Jnumed.108.059998  0.352
2010 Rinne JO, Brooks DJ, Rossor MN, Fox NC, Bullock R, Klunk WE, Mathis CA, Blennow K, Barakos J, Okello AA, Rodriguez Martinez de Liano S, Liu E, Koller M, Gregg KM, Schenk D, et al. 11C-PiB PET assessment of change in fibrillar amyloid-beta load in patients with Alzheimer's disease treated with bapineuzumab: a phase 2, double-blind, placebo-controlled, ascending-dose study. The Lancet. Neurology. 9: 363-72. PMID 20189881 DOI: 10.1016/S1474-4422(10)70043-0  0.303
2010 Brooks DJ. Examining Braak's hypothesis by imaging Parkinson's disease. Movement Disorders. 25. PMID 20187242 DOI: 10.1002/Mds.22720  0.337
2010 Pavese N, Moore RY, Scherfler C, Khan NL, Hotton G, Quinn NP, Bhatia KP, Wood NW, Brooks DJ, Lees AJ, Piccini P. In vivo assessment of brain monoamine systems in parkin gene carriers: a PET study. Experimental Neurology. 222: 120-4. PMID 20043906 DOI: 10.1016/J.Expneurol.2009.12.021  0.351
2010 Dodel R, Spottke A, Gerhard A, Reuss A, Reinecker S, Schimke N, Trenkwalder C, Sixel-Döring F, Herting B, Kamm C, Gasser T, Sawires M, Geser F, Köllensperger M, Seppi K, ... ... Brooks DJ, et al. Minocycline 1-year therapy in multiple-system-atrophy: effect on clinical symptoms and [(11)C] (R)-PK11195 PET (MEMSA-trial). Movement Disorders : Official Journal of the Movement Disorder Society. 25: 97-107. PMID 20014118 DOI: 10.1002/Mds.22732  0.316
2010 Pavese N, Politis M, Tai YF, Barker RA, Tabrizi SJ, Mason SL, Brooks DJ, Piccini P. Cortical dopamine dysfunction in symptomatic and premanifest Huntington's disease gene carriers. Neurobiology of Disease. 37: 356-61. PMID 19853661 DOI: 10.1016/J.Nbd.2009.10.015  0.318
2010 Brooks DJ, Pavese N. Continuous Dopaminergic Stimulation in Parkinson's Disease— What Have We Learned from Positron-emission Tomography? European Neurological Review. 6: 22. DOI: 10.17925/Enr.2010.05.01.22  0.348
2010 Ramlackhansingh A, Bose SK, Ahmed I, Pavese N, Brooks DJ, Turkheimer F. PATH51 Investigating adenosine A2A receptor availability in Parkinson's disease patients with and without levodopa induced dyskinesias with [11C]SCH442416 PET Journal of Neurology, Neurosurgery, and Psychiatry. 81. DOI: 10.1136/Jnnp.2010.226340.19  0.33
2010 Bose SK, Ramlackhansingh AF, Ahmed I, Pavese N, Brooks DJ, Turkheimer FE. Quantitation of adenosine A2A receptors availability in Parkinson's Disease patients with and without dyskinesias with [11C]SCH442416 PET using spectral analysis Neuroimage. 52. DOI: 10.1016/J.Neuroimage.2010.04.176  0.346
2009 Brooks DJ, Pavese N. Recent imaging advances in the diagnosis and management of Parkinson's disease. F1000 Medicine Reports. 1: 1845-1853. PMID 20948696 DOI: 10.3410/M1-82  0.338
2009 Brooks DJ. Imaging amyloid in Parkinson's disease dementia and dementia with Lewy bodies with positron emission tomography† Movement Disorders. 24. PMID 19877240 DOI: 10.1002/Mds.22581  0.327
2009 Pavese N, Khan NL, Scherfler C, Cohen L, Brooks DJ, Wood NW, Bhatia KP, Quinn NP, Lees AJ, Piccini P. Nigrostriatal dysfunction in homozygous and heterozygous parkin gene carriers: an 18F-dopa PET progression study. Movement Disorders. 24: 2260-2266. PMID 19845000 DOI: 10.1002/Mds.22817  0.337
2009 Nelissen N, Van Laere K, Thurfjell L, Owenius R, Vandenbulcke M, Koole M, Bormans G, Brooks DJ, Vandenberghe R. Phase 1 study of the Pittsburgh compound B derivative 18F-flutemetamol in healthy volunteers and patients with probable Alzheimer disease. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. 50: 1251-9. PMID 19617318 DOI: 10.2967/Jnumed.109.063305  0.307
2009 Edison P, Brooks DJ, Turkheimer FE, Archer HA, Hinz R. Strategies for the generation of parametric images of [11C]PIB with plasma input functions considering discriminations and reproducibility. Neuroimage. 48: 329-38. PMID 19591948 DOI: 10.1016/J.Neuroimage.2009.06.079  0.31
2009 Okello A, Koivunen J, Edison P, Archer HA, Turkheimer FE, NÃ¥gren K, Bullock R, Walker Z, Kennedy A, Fox NC, Rossor MN, Rinne JO, Brooks DJ. Conversion of amyloid positive and negative MCI to AD over 3 years: an 11C-PIB PET study. Neurology. 73: 754-60. PMID 19587325 DOI: 10.1212/Wnl.0B013E3181B23564  0.309
2009 Okello A, Edison P, Archer HA, Turkheimer FE, Kennedy JC, Bullock R, Walker Z, Kennedy A, Fox NCI, Rossor M, Brooks DJ. Microglial activation and amyloid deposition in mild cognitive impairment A PET study Neurology. 72: 56-62. PMID 19122031 DOI: 10.1212/01.Wnl.0000338622.27876.0D  0.305
2009 Pavese N, Brooks DJ. Imaging neurodegeneration in Parkinson's disease Biochimica Et Biophysica Acta. 1792: 722-729. PMID 18992326 DOI: 10.1016/J.Bbadis.2008.10.003  0.371
2009 Pavese N, Rivero-Bosch M, Lewis SJ, Brooks DJ. P3.024 Progression of monoaminergic dysfunction in Parkinson's disease: a longitudinal 18F-Dopa PET study Parkinsonism & Related Disorders. 15. DOI: 10.1016/S1353-8020(09)70588-7  0.343
2009 Rodda J, Dannhauser T, Cutinha D, Okello A, Shergill S, Brooks D, Walker Z. S25-05 Subjective cognitive impairment: Functional MRI during divided attention and measurement of amyloid load using 11C-PIB PET European Psychiatry. 24: 1-1. DOI: 10.1016/S0924-9338(09)70375-X  0.309
2009 Van Laere K, Vandenberghe R, Ivanoiu A, Triau E, Law I, Hasselbalch S, Buckley C, Thurfjell L, Brooks DJ. P2-011: Correlation between 18 F-GE-067 and 11 C-PIB uptake in Alzheimer's disease and MCI Alzheimer's & Dementia. 5: P263-P263. DOI: 10.1016/J.Jalz.2009.04.320  0.312
2008 Brooks DJ. The role of structural and functional imaging in parkinsonian states with a description of PET technology. Seminars in Neurology. 28: 435-445. PMID 18843572 DOI: 10.1055/S-0028-1083690  0.354
2008 Edison P, Archer HA, Gerhard A, Hinz R, Pavese N, Turkheimer FE, Hammers A, Tai YF, Fox N, Kennedy A, Rossor M, Brooks DJ. Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study. Neurobiology of Disease. 32: 412-9. PMID 18786637 DOI: 10.1016/J.Nbd.2008.08.001  0.329
2008 Brooks DJ. Optimizing levodopa therapy for Parkinson's disease with levodopa/carbidopa/entacapone: implications from a clinical and patient perspective. Neuropsychiatric Disease and Treatment. 4: 39-47. PMID 18728816 DOI: 10.2147/Ndt.S1660  0.302
2008 Politis M, Piccini P, Pavese N, Koh SB, Brooks DJ. Evidence of dopamine dysfunction in the hypothalamus of patients with Parkinson's disease: An in vivo 11C-raclopride PET study Experimental Neurology. 214: 112-116. PMID 18723016 DOI: 10.1016/J.Expneurol.2008.07.021  0.373
2008 Edison P, Rowe CC, Rinne JO, Ng S, Ahmed I, Kemppainen N, Villemagne VL, O'Keefe G, NÃ¥gren K, Chaudhury KR, Masters CL, Brooks DJ. Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomography. Journal of Neurology, Neurosurgery, and Psychiatry. 79: 1331-8. PMID 18653550 DOI: 10.1136/Jnnp.2007.127878  0.351
2008 Brooks DJ. Technology Insight: imaging neurodegeneration in Parkinson's disease Nature Reviews Neurology. 4: 267-277. PMID 18382437 DOI: 10.1038/Ncpneuro0773  0.316
2008 Sawamoto N, Piccini P, Hotton G, Pavese N, Thielemans K, Brooks DJ. Cognitive deficits and striato-frontal dopamine release in Parkinson's disease Brain. 131: 1294-1302. PMID 18362097 DOI: 10.1093/Brain/Awn054  0.34
2008 Reuter I, Tai YF, Pavese N, Chaudhuri KR, Mason S, Polkey CE, Clough C, Brooks DJ, Barker RA, Piccini P. Long-term clinical and positron emission tomography outcome of fetal striatal transplantation in Huntington's disease Journal of Neurology, Neurosurgery and Psychiatry. 79: 948-951. PMID 18356253 DOI: 10.1136/Jnnp.2007.142380  0.319
2008 Wicks P, Turner MR, Abrahams S, Hammers A, Brooks DJ, Leigh PN, Goldstein LH. Neuronal loss associated with cognitive performance in amyotrophic lateral sclerosis: an (11C)-flumazenil PET study. Amyotrophic Lateral Sclerosis : Official Publication of the World Federation of Neurology Research Group On Motor Neuron Diseases. 9: 43-9. PMID 18270878 DOI: 10.1080/17482960701737716  0.314
2008 Moore RY, Whone AL, Brooks DJ. Extrastriatal monoamine neuron function in Parkinson's disease: an 18F-dopa PET study. Neurobiology of Disease. 29: 381-90. PMID 18226536 DOI: 10.1016/J.Nbd.2007.09.004  0.361
2008 Hammers A, Panagoda P, Heckemann RA, Kelsch W, Turkheimer FE, Brooks DJ, Duncan JS, Koepp MJ. [11C]Flumazenil PET in temporal lobe epilepsy: do we need an arterial input function or kinetic modeling? Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 28: 207-16. PMID 17579659 DOI: 10.1038/Sj.Jcbfm.9600515  0.311
2007 Brooks DJ. Imaging Parkinson's disease. Handbook of Clinical Neurology. 83: 245-263. PMID 18808917 DOI: 10.1016/S0072-9752(07)83010-7  0.32
2007 Brooks DJ. Assessment of Parkinson's disease with imaging. Parkinsonism & Related Disorders. 13. PMID 18267249 DOI: 10.1016/S1353-8020(08)70015-4  0.316
2007 Hammers A, Asselin MC, Turkheimer FE, Hinz R, Osman S, Hotton G, Brooks DJ, Duncan JS, Koepp MJ. Balancing bias, reliability, noise properties and the need for parametric maps in quantitative ligand PET: [(11)C]diprenorphine test-retest data. Neuroimage. 38: 82-94. PMID 17764977 DOI: 10.1016/J.Neuroimage.2007.06.035  0.305
2007 Turner MR, Rabiner EA, Al-Chalabi A, Shaw CE, Brooks DJ, Leigh PN, Andersen PM. Cortical 5-HT1A receptor binding in patients with homozygous D90A SOD1 vs sporadic ALS. Neurology. 68: 1233-5. PMID 17420412 DOI: 10.1212/01.Wnl.0000259083.31837.64  0.305
2007 Tai YF, Pavese N, Gerhard A, Tabrizi SJ, Barker RA, Brooks DJ, Piccini P. Microglial activation in presymptomatic Huntington's disease gene carriers. Brain : a Journal of Neurology. 130: 1759-66. PMID 17400599 DOI: 10.1093/Brain/Awm044  0.358
2007 Anderson AN, Pavese N, Edison P, Tai YF, Hammers A, Gerhard A, Brooks DJ, Turkheimer FE. A systematic comparison of kinetic modelling methods generating parametric maps for [(11)C]-(R)-PK11195. Neuroimage. 36: 28-37. PMID 17398120 DOI: 10.1016/J.Neuroimage.2007.02.017  0.32
2007 Tai YF, Pavese N, Gerhard A, Tabrizi SJ, Barker RA, Brooks DJ, Piccini P. Imaging microglial activation in Huntington's disease. Brain Research Bulletin. 72: 148-51. PMID 17352938 DOI: 10.1016/J.Brainresbull.2006.10.029  0.347
2007 Brooks DJ. Imaging non-dopaminergic function in Parkinson's disease. Molecular Imaging and Biology. 9: 217-222. PMID 17340229 DOI: 10.1007/S11307-007-0084-5  0.363
2007 Mínguez-Castellanos A, Escamilla-Sevilla F, Hotton GR, Toledo-Aral JJ, Ortega-Moreno A, Méndez-Ferrer S, Martín-Linares JM, Katati MJ, Mir P, Villadiego J, Meersmans M, Pérez-García M, Brooks DJ, Arjona V, López-Barneo J. Carotid body autotransplantation in Parkinson disease: a clinical and positron emission tomography study. Journal of Neurology, Neurosurgery, and Psychiatry. 78: 825-31. PMID 17220289 DOI: 10.1136/Jnnp.2006.106021  0.349
2007 Edison P, Archer HA, Hinz R, Hammers A, Pavese N, Tai YF, Hotton G, Cutler D, Fox N, Kennedy A, Rossor M, Brooks DJ. Amyloid, hypometabolism, and cognition in Alzheimer disease: an [11C]PIB and [18F]FDG PET study. Neurology. 68: 501-8. PMID 17065593 DOI: 10.1212/01.Wnl.0000244749.20056.D4  0.336
2007 Tai YF, Ahsan RL, Yébenes JGd, Pavese N, Brooks DJ, Piccini P. Characterization of dopaminergic dysfunction in familial progressive supranuclear palsy: an 18F-dopa PET study Journal of Neural Transmission. 114: 337-340. PMID 16897607 DOI: 10.1007/S00702-006-0536-0  0.336
2007 Politis M, Piccini P, Pavese N, Koh S-, Brooks DJ. 3.119 Evidence of dopamine dysfunction in the hypothalamus of patients with Parkinson's disease: An in vivo 11 C-raclopride PET study Parkinsonism & Related Disorders. 13. DOI: 10.1016/S1353-8020(08)70827-7  0.362
2006 Pavese N, Evans AH, Tai YF, Hotton G, Brooks DJ, Lees AJ, Piccini P. Clinical correlates of levodopa-induced dopamine release in Parkinson disease: a PET study. Neurology. 67: 1612-7. PMID 17101892 DOI: 10.1212/01.Wnl.0000242888.30755.5D  0.322
2006 Brooks DJ. Dopaminergic action beyond its effects on motor function: imaging studies. Journal of Neurology. 253: 8-15. PMID 16944357 DOI: 10.1007/S00415-006-4003-5  0.312
2006 Archer HA, Edison P, Brooks DJ, Barnes J, Frost C, Yeatman T, Fox NC, Rossor MN. Amyloid load and cerebral atrophy in Alzheimer's disease: an 11C-PIB positron emission tomography study. Annals of Neurology. 60: 145-7. PMID 16802294 DOI: 10.1002/Ana.20889  0.33
2006 Pavese N, Gerhard A, Tai YF, Ho AK, Turkheimer F, Barker RA, Brooks DJ, Piccini P. Microglial activation correlates with severity in Huntington disease A clinical and PET study Neurology. 66: 1638-1643. PMID 16769933 DOI: 10.1212/01.Wnl.0000222734.56412.17  0.363
2006 Brooks DJ, Piccini P. Imaging in Parkinson’s Disease: The Role of Monoamines in Behavior Biological Psychiatry. 59: 908-918. PMID 16581032 DOI: 10.1016/J.Biopsych.2005.12.017  0.369
2006 Evans AH, Pavese N, Lawrence AD, Tai YF, Appel S, Doder M, Brooks DJ, Lees AJ, Piccini P. Compulsive drug use linked to sensitized ventral striatal dopamine transmission. Annals of Neurology. 59: 852-8. PMID 16557571 DOI: 10.1002/Ana.20822  0.326
2006 Scherfler C, Khan NL, Pavese N, Lees AJ, Quinn NP, Brooks DJ, Piccini PP. Upregulation of dopamine D2 receptors in dopaminergic drug-naive patients with Parkin gene mutations. Movement Disorders. 21: 783-788. PMID 16511856 DOI: 10.1002/Mds.20811  0.336
2006 Hu MTM, Scherfler C, Khan NL, Hajnal JV, Lees AJ, Quinn N, Wood NW, Brooks DJ. Nigral degeneration and striatal dopaminergic dysfunction in idiopathic and Parkin-linked Parkinson's disease. Movement Disorders. 21: 299-305. PMID 16211589 DOI: 10.1002/Mds.20702  0.349
2006 Gerhard A, Pavese N, Hotton G, Turkheimer F, Es M, Hammers A, Eggert K, Oertel W, Banati RB, Brooks DJ. In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease. Neurobiology of Disease. 21: 404-12. PMID 16182554 DOI: 10.1016/J.Nbd.2005.08.002  0.371
2006 Gerhard A, Trender-Gerhard I, Turkheimer F, Quinn NP, Bhatia KP, Brooks DJ. In vivo imaging of microglial activation with [11C](R)-PK11195 PET in progressive supranuclear palsy. Movement Disorders. 21: 89-93. PMID 16108021 DOI: 10.1002/Mds.20668  0.341
2006 Goerendt IK, Lawrence AD, Mehta MA, Stern JS, Odin P, Brooks DJ. Distributed neural actions of anti-parkinsonian therapies as revealed by PET. Journal of Neural Transmission (Vienna, Austria : 1996). 113: 75-86. PMID 16049638 DOI: 10.1007/S00702-005-0305-5  0.305
2006 Brooks DJ. PET Studies on the Function of Dopamine in Health and Parkinson's Disease Annals of the New York Academy of Sciences. 991: 22-35. PMID 12846971 DOI: 10.1111/J.1749-6632.2003.Tb07460.X  0.36
2006 Brooks DJ. Role of imaging in drug development for Parkinson’s disease Future Neurology. 1: 335-342. DOI: 10.2217/14796708.1.3.335  0.348
2006 Kent S, Bernstein R, Abbott T, Bigelow B, Brooks D, Doel P, Flaugher B, Gladders M, Walker A, Worswick S. Preliminary optical design for a 2.2 degree diameter prime focus corrector for the Blanco 4 meter telescope Proceedings of Spie. 6269: 626937. DOI: 10.1117/12.672097  0.304
2006 Piccini P, Pavese N, Hagell P, Reimer J, Bjorklund A, Oertel WH, Quinn NP, Brooks DJ, Lindvall O. Reply: Rate of progression determines the clinical outcome after neural transplantation in Parkinson's disease [2] Brain. 129: E49. DOI: 10.1093/Brain/Awl113  0.318
2006 Edison P, Rowe CC, Ahmed I, Villemagne VL, Rinne J, Brooks DJ. II.P13 Amyloid load in Parkinson's Disease Dementia (PDD) and Lewy Body Dementia (LBD) measured with 11C-PIB PET Parkinsonism & Related Disorders. 12: 28. DOI: 10.1016/S1353-8020(07)70092-5  0.315
2005 Brooks DJ. Imaging studies in drug development: Parkinson's disease. Drug Discovery Today: Technologies. 2: 317-321. PMID 24982007 DOI: 10.1016/J.Ddtec.2005.11.001  0.354
2005 Khan NL, Jain S, Lynch JM, Pavese N, Abou-Sleiman P, Holton JL, Healy DG, Gilks WP, Sweeney MG, Ganguly M, Gibbons V, Gandhi S, Vaughan J, Eunson LH, Katzenschlager R, ... ... Brooks D, et al. Mutations in the gene LRRK2 encoding dardarin (PARK8) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data. Brain : a Journal of Neurology. 128: 2786-96. PMID 16272164 DOI: 10.1093/Brain/Awh667  0.333
2005 Cheesman AL, Barker RA, Lewis SJ, Robbins TW, Owen AM, Brooks DJ. Lateralisation of striatal function: evidence from 18F-dopa PET in Parkinson's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 76: 1204-10. PMID 16107352 DOI: 10.1136/Jnnp.2004.055079  0.357
2005 Brooks DJ. Positron emission tomography and single-photon emission computed tomography in central nervous system drug development. Neurorx. 2: 226-236. PMID 15897947 DOI: 10.1602/Neurorx.2.2.226  0.312
2005 Turner MR, Gerhard A, Al-Chalabi A, Shaw CE, Hughes RA, Banati RB, Brooks DJ, Leigh PN. Mills' and other isolated upper motor neurone syndromes: in vivo study with 11C-(R)-PK11195 PET. Journal of Neurology, Neurosurgery, and Psychiatry. 76: 871-4. PMID 15897516 DOI: 10.1136/Jnnp.2004.047902  0.33
2005 Remy P, Doder M, Lees A, Turjanski N, Brooks D. Depression in Parkinson's disease: loss of dopamine and noradrenaline innervation in the limbic system. Brain. 128: 1314-1322. PMID 15716302 DOI: 10.1093/Brain/Awh445  0.314
2005 Turner MR, Rabiner EA, Hammers A, Al-Chalabi A, Grasby PM, Shaw CE, Brooks DJ, Leigh PN. [11C]-WAY100635 PET demonstrates marked 5-HT1A receptor changes in sporadic ALS. Brain : a Journal of Neurology. 128: 896-905. PMID 15689356 DOI: 10.1093/Brain/Awh428  0.305
2005 Ravina B, Eidelberg D, Ahlskog JE, Albin RL, Brooks DJ, Carbon M, Dhawan V, Feigin A, Fahn S, Guttman M, Gwinn-Hardy K, McFarland H, Innis R, Katz RG, Kieburtz K, et al. The role of radiotracer imaging in Parkinson disease. Neurology. 64: 208-15. PMID 15668415 DOI: 10.1212/01.Wnl.0000149403.14458.7F  0.343
2005 Khan NL, Scherfler C, Graham E, Bhatia KP, Quinn N, Lees AJ, Brooks DJ, Wood NW, Piccini P. Dopaminergic dysfunction in unrelated, asymptomatic carriers of a single Parkin mutation Neurology. 64: 134-136. PMID 15642918 DOI: 10.1212/01.Wnl.0000148725.48740.6D  0.34
2005 Chaudhuri KR, Buxton-Thomas M, Dhawan V, Peng R, Meilak C, Brooks DJ. Long duration asymmetrical postural tremor is likely to predict development of Parkinson’s disease and not essential tremor: clinical follow up study of 13 cases Journal of Neurology, Neurosurgery, and Psychiatry. 76: 115-117. PMID 15608009 DOI: 10.1136/Jnnp.2004.046292  0.303
2005 Edison P, Archer H, Hinz R, Hammers A, Gerhard A, Pavese N, Tai Y, Hotton G, Cuttler D, Fox N, Rossor M, Brooks DJ. Correlation of regional cerebral amyloid load in Alzheimer's disease, measured with [11C]-PIB PET using spectral analysis and tissue uptake ratios, with performance on recognition memory tests. Journal of Cerebral Blood Flow and Metabolism. 25. DOI: 10.1038/Sj.Jcbfm.9591524.0591  0.31
2004 Brooks DJ. Positron emission tomography imaging of transplant function Neurorx. 1: 482-491. PMID 15717049 DOI: 10.1602/Neurorx.1.4.482  0.344
2004 Brooks DJ. Neuroimaging in Parkinson’s disease Neurorx. 1: 243-254. PMID 15717025 DOI: 10.1602/Neurorx.1.2.243  0.328
2004 Whone AL, Von Spiczak S, Edwards M, Valente EM, Hammers A, Bhatia KP, Brooks DJ. Opioid binding in DYT1 primary torsion dystonia: An 11C-diprenorphine PET study Movement Disorders. 19: 1498-1503. PMID 15390064 DOI: 10.1002/Mds.20238  0.306
2004 Gerhard A, Watts J, Trender-Gerhard I, Turkheimer F, Banati RB, Bhatia K, Brooks DJ. In vivo imaging of microglial activation with [11C](R)-PK11195 PET in corticobasal degeneration. Movement Disorders : Official Journal of the Movement Disorder Society. 19: 1221-6. PMID 15390000 DOI: 10.1002/Mds.20162  0.35
2004 Scherfler C, Khan NL, Pavese N, Eunson L, Graham E, Lees AJ, Quinn NP, Wood NW, Brooks DJ, Piccini PP. Striatal and cortical pre- and postsynaptic dopaminergic dysfunction in sporadic parkin-linked parkinsonism. Brain : a Journal of Neurology. 127: 1332-42. PMID 15090472 DOI: 10.1093/Brain/Awh150  0.372
2004 Turner MR, Cagnin A, Turkheimer FE, Miller CC, Shaw CE, Brooks DJ, Leigh PN, Banati RB. Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis: an [11C](R)-PK11195 positron emission tomography study. Neurobiology of Disease. 15: 601-9. PMID 15056468 DOI: 10.1016/J.Nbd.2003.12.012  0.316
2004 Goerendt IK, Lawrence AD, Brooks DJ. Reward processing in health and Parkinson's disease: neural organization and reorganization. Cerebral Cortex (New York, N.Y. : 1991). 14: 73-80. PMID 14654458 DOI: 10.1093/Cercor/Bhg105  0.329
2003 Brooks DJ, Frey KA, Marek KL, Oakes D, Paty D, Prentice R, Shults CW, Stoessl AJ. Assessment of neuroimaging techniques as biomarkers of the progression of Parkinson's disease Experimental Neurology. 184. PMID 14597329 DOI: 10.1016/J.Expneurol.2003.08.008  0.354
2003 Gerhard A, Banati RB, Goerres GB, Cagnin A, Myers R, Gunn RN, Turkheimer F, Good CD, Mathias CJ, Quinn N, Schwarz J, Brooks DJ. [11C](R)-PK11195 PET imaging of microglial activation in multiple system atrophy. Neurology. 61: 686-9. PMID 12963764 DOI: 10.1212/01.Wnl.0000078192.95645.E6  0.309
2003 Moore RY, Whone AL, McGowan S, Brooks DJ. Monoamine neuron innervation of the normal human brain: an 18F-DOPA PET study. Brain Research. 982: 137-45. PMID 12915249 DOI: 10.1016/S0006-8993(03)02721-5  0.352
2003 Whone AL, Watts RL, Stoessl AJ, Davis M, Reske S, Nahmias C, Lang AE, Rascol O, Ribeiro MJ, Remy P, Poewe WH, Hauser RA, Brooks DJ. Slower progression of Parkinson's disease with ropinirole versus levodopa: The REAL-PET study. Annals of Neurology. 54: 93-101. PMID 12838524 DOI: 10.1002/Ana.10609  0.369
2003 Piccini P, Pavese N, Brooks DJ. Endogenous dopamine release after pharmacological challenges in Parkinson's disease. Annals of Neurology. 53: 647-653. PMID 12730999 DOI: 10.1002/Ana.10526  0.327
2003 Pavese N, Andrews TC, Brooks DJ, Ho AK, Rosser AE, Barker RA, Robbins TW, Sahakian BJ, Dunnett SB, Piccini P. Progressive striatal and cortical dopamine receptor dysfunction in Huntington's disease: a PET study. Brain : a Journal of Neurology. 126: 1127-35. PMID 12690052 DOI: 10.1093/Brain/Awg119  0.361
2003 Gill SS, Patel NK, Hotton GR, O'Sullivan K, McCarter R, Bunnage M, Brooks DJ, Svendsen CN, Heywood P. Direct brain infusion of glial cell line-derived neurotrophic factor in Parkinson disease. Nature Medicine. 9: 589-95. PMID 12669033 DOI: 10.1038/Nm850  0.352
2003 Brooks DJ. Imaging end points for monitoring neuroprotection in Parkinson's disease. Annals of Neurology. 53. PMID 12666103 DOI: 10.1002/Ana.10480  0.336
2003 Whone AL, Moore RY, Piccini PP, Brooks DJ. Plasticity of the nigropallidal pathway in Parkinson's disease. Annals of Neurology. 53: 206-13. PMID 12557287 DOI: 10.1002/Ana.10427  0.335
2003 Goerendt IK, Messa C, Lawrence AD, Grasby PM, Piccini P, Brooks DJ. Dopamine release during sequential finger movements in health and Parkinson's disease: a PET study. Brain : a Journal of Neurology. 126: 312-25. PMID 12538400 DOI: 10.1093/Brain/Awg035  0.343
2002 Rakshi JS, Pavese N, Uema T, Ito K, Morrish PK, Bailey DL, Brooks DJ. A comparison of the progression of early Parkinson's disease in patients started on ropinirole or L-dopa: An 18F-dopa PET study Journal of Neural Transmission. 109: 1433-1443. PMID 12486484 DOI: 10.1007/S00702-002-0753-0  0.34
2002 Hu MTM, Chaudhuri KR, Jarosz J, Yaguez L, Brooks DJ. An imaging study of parkinsonism among African-Caribbean and Indian London communities. Movement Disorders. 17: 1321-1328. PMID 12465076 DOI: 10.1002/Mds.10261  0.36
2002 Khan NL, Valente EM, Bentivoglio AR, Wood NW, Albanese A, Brooks DJ, Piccini P. Clinical and subclinical dopaminergic dysfunction in PARK6-linked parkinsonism: An 18F-dopa PET study Annals of Neurology. 52: 849-853. PMID 12447943 DOI: 10.1002/Ana.10417  0.381
2002 Boecker H, Ceballos-Baumann AO, Bartenstein P, Dagher A, Forster K, Haslinger B, Brooks DJ, Schwaiger M, Conrad B. A H(2)(15)O positron emission tomography study on mental imagery of movement sequences--the effect of modulating sequence length and direction. Neuroimage. 17: 999-1009. PMID 12377173 DOI: 10.1006/Nimg.2002.1139  0.497
2002 Hammers A, Koepp MJ, Hurlemann R, Thom M, Richardson MP, Brooks DJ, Duncan JS. Abnormalities of grey and white matter [11C]flumazenil binding in temporal lobe epilepsy with normal MRI. Brain. 125: 2257-2271. PMID 12244083 DOI: 10.1093/Brain/Awf233  0.314
2002 Khan NL, Brooks DJ, Pavese N, Sweeney MG, Wood NW, Lees AJ, Piccini P. Progression of nigrostriatal dysfunction in a parkin kindred: an [18F]dopa PET and clinical study. Brain. 125: 2248-2256. PMID 12244082 DOI: 10.1093/Brain/Awf237  0.347
2002 Hagell P, Piccini P, Björklund A, Brundin P, Rehncrona S, Widner H, Crabb L, Pavese N, Oertel WH, Quinn N, Brooks DJ, Lindvall O. Dyskinesias following neural transplantation in Parkinson's disease. Nature Neuroscience. 5: 627-8. PMID 12042822 DOI: 10.1038/Nn863  0.333
2002 Ito K, Nagano‐Saito A, Kato T, Arahata Y, Nakamura A, Kawasumi Y, Hatano K, Abe Y, Yamada T, Kachi T, Brooks DJ. Striatal and extrastriatal dysfunction in Parkinson's disease with dementia: A 6-[18F]fluoro-L-dopa PET study Brain. 125: 1358-1365. PMID 12023324 DOI: 10.1093/Brain/Awf134  0.355
2002 Kjaer TW, Bertelsen C, Piccini P, Brooks D, Alving J, Lou HC. Increased dopamine tone during meditation-induced change of consciousness Cognitive Brain Research. 13: 255-259. PMID 11958969 DOI: 10.1016/S0926-6410(01)00106-9  0.304
2002 Brunt ER, Brooks DJ, Korczyn AD, Montastruc J-, Stocchi F. A six-month multicentre, double-blind, bromocriptine-controlled study of the safety and efficacy of ropinirole in the treatment of patients with Parkinson's disease not optimally controlled by L-dopa. Journal of Neural Transmission. 109: 489-502. PMID 11956968 DOI: 10.1007/S007020200040  0.305
2002 Brooks DJ. Diagnosis and management of atypical parkinsonian syndromes. Journal of Neurology, Neurosurgery, and Psychiatry. 72: 10-16. PMID 11870198 DOI: 10.1136/Jnnp.72.Suppl_1.I10  0.317
2002 Nicholl DJ, Vaughan JR, Khan NL, Ho SL, Aldous DE, Lincoln S, Farrer M, Gayton JD, Davis MB, Piccini P, Daniel SE, Lennox GG, Brooks DJ, Williams AC, Wood NW. Two large British kindreds with familial Parkinson's disease: a clinico-pathological and genetic study. Brain : a Journal of Neurology. 125: 44-57. PMID 11834592 DOI: 10.1093/Brain/Awf013  0.326
2002 Ceravolo R, Piccini P, Bailey DL, Jorga KM, Bryson H, Brooks DJ. 18F-dopa PET evidence that tolcapone acts as a central COMT inhibitor in Parkinson's disease Synapse. 43: 201-207. PMID 11793426 DOI: 10.1002/Syn.10034  0.347
2002 Boecker H, Ceballos-Baumann A, Bartenstein P, Dagher A, Forster K, Haslinger B, Brooks D, Schwaiger M, Conrad B. A H215O Positron Emission Tomography Study on Mental Imagery of Movement Sequences—The Effect of Modulating Sequence Length and Direction Neuroimage. 17: 999-1009. DOI: 10.1006/nimg.2002.1139  0.41
2001 Brooks DJ. Functional imaging studies on dopamine and motor control. Journal of Neural Transmission. 108: 1283-1298. PMID 11768627 DOI: 10.1007/S007020100005  0.304
2001 Hirani E, Gillies J, Karasawa A, Shimada J, Kase H, Opacka-Juffry J, Osman S, Luthra SK, Hume SP, Brooks DJ. Evaluation of [4-O-methyl-11C]KW-6002 as a potential PET ligand for mapping central adenosine A2A receptors in rats Synapse. 42: 164-176. PMID 11746713 DOI: 10.1002/Syn.1110  0.318
2001 Richardson MP, Hammers A, Brooks DJ, Duncan JS. Benzodiazepine-GABA(A) receptor binding is very low in dysembryoplastic neuroepithelial tumor: a PET study. Epilepsia. 42: 1327-1334. PMID 11737168 DOI: 10.1046/J.1528-1157.2001.44100.X  0.336
2001 Piccini P, Yebenez Jd, Lees AJ, Ceravolo R, Turjanski N, Pramstaller P, Brooks DJ. Familial progressive supranuclear palsy: detection of subclinical cases using 18F-dopa and 18fluorodeoxyglucose positron emission tomography. Jama Neurology. 58: 1846-1851. PMID 11708994 DOI: 10.1001/Archneur.58.11.1846  0.339
2001 Cagnin A, Brooks DJ, Kennedy AM, Gunn RN, Myers R, Turkheimer FE, Jones T, Banati RB. In-vivo measurement of activated microglia in dementia. Lancet. 358: 461-7. PMID 11513911 DOI: 10.1016/S0140-6736(01)05625-2  0.341
2001 Hu MT, White SJ, Chaudhuri KR, Morris RG, Bydder GM, Brooks DJ. Correlating rates of cerebral atrophy in Parkinson's disease with measures of cognitive decline. Journal of Neural Transmission (Vienna, Austria : 1996). 108: 571-80. PMID 11459077 DOI: 10.1007/S007020170057  0.334
2001 Hu M, White SJ, Herlihy AH, Chaudhuri KR, Hajnal JV, Brooks DJ. A comparison of 18F-dopa PET and inversion recovery MRI in the diagnosis of Parkinson’s disease Neurology. 56: 1195-1200. PMID 11342685 DOI: 10.1212/Wnl.56.9.1195  0.347
2001 Dagher A, Owen AM, Boecker H, Brooks DJ. The role of the striatum and hippocampus in planning: a PET activation study in Parkinson's disease. Brain : a Journal of Neurology. 124: 1020-32. PMID 11335704 DOI: 10.1093/Brain/124.5.1020  0.542
2001 Samuel M, Ceballos-Baumann AO, Boecker H, Brooks DJ. Motor imagery in normal subjects and Parkinson's disease patients: an H215O PET study. Neuroreport. 12: 821-8. PMID 11277590 DOI: 10.1097/00001756-200103260-00040  0.314
2001 Goerendt IK, Messa C, Lawrence AD, Piccini P, Grasby PM, Brooks DJ. Endogenous dopamine release during sequential movement in healthy volunteers and patients with Parkinson's disease: a PET study Neuroimage. 13: 1172. DOI: 10.1016/S1053-8119(01)92492-9  0.345
2000 Brooks DJ. Monitoring neuroprotection and restorative therapies in Parkinson’s disease with PET Journal of Neural Transmission-Supplement. 125-37. PMID 11205135 DOI: 10.1007/978-3-7091-6301-6_8  0.344
2000 Brooks DJ, Piccini P. Chapter 14 Non-invasive in vivo imaging of transplant function Progress in Brain Research. 127: 321-332. PMID 11142033 DOI: 10.1016/S0079-6123(00)27015-5  0.339
2000 Piccini P, Lindvall O, Björklund A, Brundin P, Hagell P, Ceravolo R, Oertel W, Quinn N, Samuel M, Rehncrona S, Widner H, Brooks DJ. Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts. Annals of Neurology. 48: 689-95. PMID 11079531 DOI: 10.1002/1531-8249(200011)48:5<689::Aid-Ana1>3.0.Co;2-N  0.366
2000 Brooks DJ. PET studies and motor complications in Parkinson's disease Trends in Neurosciences. 23. PMID 11052227 DOI: 10.1016/S1471-1931(00)00016-1  0.365
2000 Brooks DJ. Morphological and functional imaging studies on the diagnosis and progression of Parkinson's disease. Journal of Neurology. 247: 11-18. PMID 10991656 DOI: 10.1007/Pl00007755  0.352
2000 Brooks DJ. Imaging basal ganglia function Journal of Anatomy. 196: 543-554. PMID 10923986 DOI: 10.1046/J.1469-7580.2000.19640543.X  0.322
2000 Hu MT, Taylor-Robinson SD, Chaudhuri KR, Bell JD, Labbé C, Cunningham VJ, Koepp MJ, Hammers A, Morris RG, Turjanski N, Brooks DJ. Cortical dysfunction in non-demented Parkinson's disease patients: a combined (31)P-MRS and (18)FDG-PET study. Brain : a Journal of Neurology. 123: 340-52. PMID 10648441 DOI: 10.1093/Brain/123.2.340  0.351
2000 Reuter I, Hu MTM, Andrews TC, Brooks DJ, Clough C, Ray Chaudhuri K. Late onset levodopa responsive Huntington's disease with minimal chorea masquerading as Parkinson plus syndrome Journal of Neurology Neurosurgery and Psychiatry. 68: 238-241. PMID 10644798 DOI: 10.1136/Jnnp.68.2.238  0.326
2000 Chaudhuri KR, Hu MTM, Brooks DJ. Atypical parkinsonism in Afro-Caribbean and Indian origin immigrants to the UK. Movement Disorders. 15: 18-23. PMID 10634237 DOI: 10.1002/1531-8257(200001)15:1<18::Aid-Mds1005>3.0.Co;2-Z  0.339
1999 Banati RB, Goerres GW, Myers R, Gunn RN, Turkheimer FE, Kreutzberg GW, Brooks DJ, Jones T, Duncan JS. [11C](R)-PK11195 positron emission tomography imaging of activated microglia in vivo in Rasmussen's encephalitis. Neurology. 53: 2199-203. PMID 10599809 DOI: 10.1212/Wnl.53.9.2199  0.327
1999 Andrews TC, Weeks RA, Turjanski N, Gunn RN, Watkins LH, Sahakian B, Hodges JR, Rosser AE, Wood NW, Brooks DJ. Huntington's disease progression. PET and clinical observations. Brain : a Journal of Neurology. 122: 2353-63. PMID 10581228 DOI: 10.1093/Brain/122.12.2353  0.322
1999 Dagher A, Owen AM, Boecker H, Brooks DJ. Mapping the network for planning: a correlational PET activation study with the Tower of London task. Brain : a Journal of Neurology. 122: 1973-87. PMID 10506098 DOI: 10.1093/Brain/122.10.1973  0.495
1999 Rakshi JS, Uema T, Ito K, Bailey DL, Morrish PK, Ashburner J, Dagher A, Jenkins IH, Friston KJ, Brooks DJ. Frontal, midbrain and striatal dopaminergic function in early and advanced Parkinson's disease A 3D [(18)F]dopa-PET study. Brain : a Journal of Neurology. 122: 1637-50. PMID 10468504 DOI: 10.1093/Brain/122.9.1637  0.54
1999 Brooks DJ. Functional imaging of Parkinson's disease: is it possible to detect brain areas for specific symptoms? Journal of Neural Transmission-Supplement. 56: 139-153. PMID 10370908 DOI: 10.1007/978-3-7091-6360-3_8  0.331
1999 Hu MT, Taylor-Robinson SD, Chaudhuri KR, Bell JD, Morris RG, Clough C, Brooks DJ, Turjanski N. Evidence for cortical dysfunction in clinically non-demented patients with Parkinson's disease: a proton MR spectroscopy study. Journal of Neurology, Neurosurgery, and Psychiatry. 67: 20-6. PMID 10369817 DOI: 10.1136/Jnnp.67.1.20  0.31
1999 Taylor-Robinson SD, Turjanski N, Bhattacharya S, Seery JP, Sargentoni J, Brooks DJ, Bryant DJ, Cox IJ. A proton magnetic resonance spectroscopy study of the striatum and cerebral cortex in Parkinson's disease. Metabolic Brain Disease. 14: 45-55. PMID 10348313 DOI: 10.1023/A:1020609530444  0.316
1999 Ito K, Morrish PK, Rakshi JS, Uema T, Ashburner J, Bailey DL, Friston KJ, Brooks DJ. Statistical parametric mapping with 18F-dopa PET shows bilaterally reduced striatal and nigral dopaminergic function in early Parkinson's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 66: 754-8. PMID 10329749 DOI: 10.1136/Jnnp.66.6.754  0.373
1999 Turjanski N, Lees AJ, Brooks DJ. Striatal dopaminergic function in restless legs syndrome: 18F-dopa and 11C-raclopride PET studies Neurology. 52: 932-937. PMID 10102408 DOI: 10.1212/Wnl.52.5.932  0.351
1999 Boecker H, Brooks DJ. Functional imaging of tremor. Movement Disorders : Official Journal of the Movement Disorder Society. 64-72. PMID 9827597 DOI: 10.1002/Mds.870131311  0.315
1998 Andrews TC, Brooks DJ. Advances in the understanding of early Huntington's disease using the functional imaging techniques of PET and SPET Molecular Medicine Today. 4: 532-539. PMID 9866823 DOI: 10.1016/S1357-4310(98)01371-9  0.371
1998 Olanow CW, Jenner P, Brooks D. Dopamine agonists and neuroprotection in Parkinson's disease Annals of Neurology. 44: S167-S174. PMID 9749590 DOI: 10.1002/Ana.410440725  0.313
1998 Brooks DJ. The early diagnosis of parkinson's disease Annals of Neurology. 44. PMID 9749569 DOI: 10.1002/Ana.410440704  0.336
1998 Lawrence AD, Weeks RA, Brooks DJ, Andrews TC, Watkins LH, Harding AE, Robbins TW, Sahakian BJ. The relationship between striatal dopamine receptor binding and cognitive performance in Huntington's disease. Brain : a Journal of Neurology. 121: 1343-55. PMID 9679785 DOI: 10.1093/Brain/121.7.1343  0.332
1998 Richardson MP, Koepp MJ, Brooks DJ, Coull JT, Grasby P, Fish DR, Duncan JS. Cerebral activation in malformations of cortical development. Brain : a Journal of Neurology. 121: 1295-304. PMID 9679781 DOI: 10.1093/Brain/121.7.1295  0.322
1998 Koepp MJ, Gunn RN, Lawrence AD, Cunningham VJ, Dagher A, Jones T, Brooks DJ, Bench CJ, Grasby PM. Evidence for striatal dopamine release during a video game. Nature. 393: 266-8. PMID 9607763 DOI: 10.1038/30498  0.504
1998 Koepp MJ, Hand KS, Labbé C, Richardson MP, Van Paesschen W, Baird VH, Cunningham VJ, Bowery NG, Brooks DJ, Duncan JS. In vivo [11C]flumazenil-PET correlates with ex vivo [3H]flumazenil autoradiography in hippocampal sclerosis. Annals of Neurology. 43: 618-26. PMID 9585356 DOI: 10.1002/Ana.410430510  0.31
1998 Samuel M, Caputo E, Brooks DJ, Schrag A, Scaravilli T, Branston NM, Rothwell JC, Marsden CD, Thomas DGT, Lees AJ, Quinn NP. A study of medial pallidotomy for Parkinson's disease: Clinical outcome, MRI location and complications Brain. 121: 59-75. PMID 9549488 DOI: 10.1093/Brain/121.1.59  0.3
1998 Playford ED, Passingham RE, Marsden CD, Brooks DJ. Increased activation of frontal areas during arm movement in idiopathic torsion dystonia. Movement Disorders : Official Journal of the Movement Disorder Society. 13: 309-18. PMID 9539346 DOI: 10.1002/Mds.870130218  0.344
1998 Morrish PK, Rakshi JS, Bailey DL, Sawle GV, Brooks DJ. Measuring the rate of progression and estimating the preclinical period of Parkinson's disease with [18F]dopa PET Journal of Neurology Neurosurgery and Psychiatry. 64: 314-319. PMID 9527140 DOI: 10.1136/Jnnp.64.3.314  0.362
1998 Boecker H, Dagher A, Ceballos-Baumann AO, Passingham RE, Samuel M, Friston KJ, Poline J, Dettmers C, Conrad B, Brooks DJ. Role of the human rostral supplementary motor area and the basal ganglia in motor sequence control: investigations with H2 15O PET. Journal of Neurophysiology. 79: 1070-80. PMID 9463462 DOI: 10.1152/Jn.1998.79.2.1070  0.507
1998 Korczyn AD, Brooks DJ, Brunt ER, Poewe WH, Rascol O, Stocchi F. Ropinirole versus bromocriptine in the treatment of early Parkinson's disease : A 6-month interim report of a 3-year study Movement Disorders. 13: 46-51. PMID 9452325 DOI: 10.1002/Mds.870130112  0.314
1998 Rascol O, Brooks DJ, Brunt ER, Korczyn AD, Poewe WH, Stocchi F. Ropinirole in the treatment of early Parkinson's disease: A 6-month interim report of a 5-year levodopa-controlled study Movement Disorders. 13: 39-45. PMID 9452324 DOI: 10.1002/Mds.870130111  0.325
1998 Koepp MJ, Gunn RN, Lawrence AD, Cunningham VJ, Dagher A, Jones T, Brooks DJ, Bench CJ, Grasby PM. Evidence for Endogenous Dopamine Release Induced by Behavioural Manipulation Neuroimage. 7. DOI: 10.1016/S1053-8119(18)31920-7  0.466
1998 Grasby PM, Koepp MJ, Gunn RN, Cunningham VJ, Lawrence AD, Dagher A, Jones T, Brooks DJ, Bench CJ. Evidence for dopamine release during a videogame using [11C]Raclopride PET Neuroimage. 7: S28. DOI: 10.1016/S1053-8119(18)30861-9  0.504
1998 Brooks DJ. Positron emission tomography studies in movement disorders. Neurosurgery Clinics of North America. 9: 263-282. DOI: 10.1016/S1042-3680(18)30263-8  0.336
1997 Koepp MJ, Richardson MP, Brooks DJ, Cunningham VJ, Duncan JS. Central Benzodiazepine/γ‐Aminobutyric AcidA Receptors in Idiopathic Generalized Epilepsy: An [11C]Flumazenil Positron Emission Tomography Study Epilepsia. 38: 1089-1097. PMID 9579955 DOI: 10.1111/J.1528-1157.1997.Tb01198.X  0.346
1997 Turjanski N, Brooks DJ. PET and the investigation of dementia in the parkinsonian patient Journal of Neural Transmission-Supplement. 51: 37-48. PMID 9470127 DOI: 10.1007/978-3-7091-6846-2_4  0.368
1997 Turjanski N, Pentland B, Lees AJ, Brooks DJ. Parkinsonism associated with acute intracranial hematomas: an [18F]dopa positron-emission tomography study. Movement Disorders. 12: 1035-1038. PMID 9399232 DOI: 10.1002/Mds.870120630  0.33
1997 Spence SA, Brooks DJ, Hirsch SR, Liddle PF, Meehan J, Grasby PM. A PET study of voluntary movement in schizophrenic patients experiencing passivity phenomena (delusions of alien control) Brain. 120: 1997-2011. PMID 9397017 DOI: 10.1093/Brain/120.11.1997  0.311
1997 Richardson MP, Friston KJ, Sisodiya SM, Koepp MJ, Ashburner J, Free SL, Brooks DJ, Duncan JS. Cortical grey matter and benzodiazepine receptors in malformations of cortical development. A voxel-based comparison of structural and functional imaging data. Brain : a Journal of Neurology. 120: 1961-73. PMID 9397014 DOI: 10.1093/Brain/120.11.1961  0.329
1997 Piccini P, Weeks RA, Brooks DJ. Alterations in opioid receptor binding in Parkinson's disease patients with levodopa-induced dyskinesias. Annals of Neurology. 42: 720-726. PMID 9392571 DOI: 10.1002/Ana.410420508  0.314
1997 Brooks DJ. Motor disturbance and brain functional imaging in Parkinson's disease European Neurology. 38: 26-32. PMID 9387800 DOI: 10.1159/000113473  0.378
1997 Weeks RA, Ceballos-Baumann A, Piccini P, Boecker H, Harding AE, Brooks DJ. Cortical control of movement in Huntington's disease. A PET activation study. Brain : a Journal of Neurology. 1569-78. PMID 9313640 DOI: 10.1093/Brain/120.9.1569  0.355
1997 Weeks RA, Cunningham VJ, Piccini P, Waters S, Harding AE, Brooks DJ. 11C-diprenorphine binding in Huntington's disease: a comparison of region of interest analysis with statistical parametric mapping. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 17: 943-9. PMID 9307607 DOI: 10.1097/00004647-199709000-00003  0.341
1997 Samuel M, Ceballos-Baumann AO, Turjanski N, Boecker H, Gorospe A, Linazasoro G, Holmes AP, DeLong MR, Vitek JL, Thomas DG, Quinn NP, Obeso JA, Brooks DJ. Pallidotomy in Parkinson's disease increases supplementary motor area and prefrontal activation during performance of volitional movements an H2(15)O PET study. Brain : a Journal of Neurology. 120: 1301-13. PMID 9278624 DOI: 10.1093/Brain/120.8.1301  0.332
1997 Brooks DJ. Advances in imaging Parkinson's disease. Current Opinion in Neurology. 10: 327-331. PMID 9266157 DOI: 10.1097/00019052-199708000-00008  0.348
1997 Wenning GK, Odin P, Morrish P, Rehncrona S, Widner H, Brundin P, Rothwell JC, Brown R, Gustavii B, Hagell P, Jahanshahi M, Sawle G, Björklund A, Brooks DJ, Marsden CD, et al. Short- and long-term survival and function of unilateral intrastriatal dopaminergic grafts in Parkinson's disease. Annals of Neurology. 42: 95-107. PMID 9225690 DOI: 10.1002/Ana.410420115  0.318
1997 Turjanski N, Lees AJ, Brooks DJ. Dopaminergic function in patients with posttraumatic parkinsonism: An 18F-dopa PET study Neurology. 49: 183-189. PMID 9222188 DOI: 10.1212/Wnl.49.1.183  0.356
1997 Samuel M, Ceballos-Baumann AO, Blin J, Uema T, Boecker H, Passingham RE, Brooks DJ. Evidence for lateral premotor and parietal overactivity in Parkinson's disease during sequential and bimanual movements. A PET study. Brain : a Journal of Neurology. 120: 963-76. PMID 9217681 DOI: 10.1093/Brain/120.6.963  0.339
1997 Piccini P, Morrish PK, Turjanski N, Sawle GV, Burn DJ, Weeks RA, Mark MH, Maraganore DM, Lees AJ, Brooks DJ. Dopaminergic function in familial Parkinson's disease: A clinical and 18F‐dopa positron emission tomography study Annals of Neurology. 41: 222-229. PMID 9029071 DOI: 10.1002/Ana.410410213  0.355
1997 Boecker H, Wills AJ, Ceballos-Baumann A, Samuel M, Thomas DG, Marsden CD, Brooks DJ. Stereotactic thalamotomy in tremor-dominant Parkinson's disease: an H2(15)O PET motor activation study. Annals of Neurology. 41: 108-11. PMID 9005873 DOI: 10.1002/Ana.410410118  0.309
1996 Abrahams S, Goldstein LH, Kew JJM, Brooks DJ, Lloyd CM, Frith CD, Leigh PN. Frontal lobe dysfunction in amyotrophic lateral sclerosis. A PET study Brain. 119: 2105-2120. PMID 9010014 DOI: 10.1093/Brain/119.6.2105  0.305
1996 Morrish PK, Sawle GV, Brooks DJ. Regional changes in ( 18F)dopa metabolism in the striatum in Parkinson's disease Brain. 119: 2097-2103. PMID 9010013 DOI: 10.1093/Brain/119.6.2097  0.363
1996 Brooks DJ. Functional imaging techniques in the diagnosis of non-Alzheimer dementias Journal of Neural Transmission-Supplement. 47: 155-167. PMID 8841963 DOI: 10.1007/978-3-7091-6892-9_10  0.331
1996 Morrish PK, Sawle GV, Brooks DJ. An [18F]dopa–PET and clinical study of the rate of progression in Parkinson’s disease Brain. 119: 585-591. PMID 8800950 DOI: 10.1093/Brain/119.2.585  0.304
1996 Richardson MP, Koepp MJ, Duncan JS, Brooks DJ, Fish DR. Benzodiazepine receptors in focal epilepsy with cortical dysgenesis: An 11C‐flumazenil PET study Annals of Neurology. 40: 188-198. PMID 8773600 DOI: 10.1002/Ana.410400210  0.314
1996 Weeks RA, Turjanski N, Brooks DJ. Tourette's syndrome: a disorder of cingulate and orbitofrontal function? Qjm: An International Journal of Medicine. 89: 401-408. PMID 8758042 DOI: 10.1093/Qjmed/89.6.401  0.315
1996 Wills AJ, Thompson PD, Findley LJ, Brooks DJ. A positron emission tomography study of primary orthostatic tremor. Neurology. 46: 747-52. PMID 8618676 DOI: 10.1212/Wnl.46.3.747  0.302
1996 Boecker H, Dagher A, Ceballos-Baumann A, Passingham R, Samuel M, Friston K, Dettmers C, Conrad B, Brooks D. P449 The role of rostral supplementary motor area and basal ganglia in motor sequence control Electroencephalography and Clinical Neurophysiology. 99: 379. DOI: 10.1016/0013-4694(96)88624-X  0.396
1995 O'Sullivan EP, Jenkins IH, Henderson L, Kennard C, Brooks DJ. The functional anatomy of remembered saccades: a PET study. Neuroreport. 6: 2141-2144. PMID 8595189 DOI: 10.1097/00001756-199511000-00011  0.305
1995 Hume SP, Opacka-Juffry J, Myers R, Ahier RG, Ashworth S, Brooks DJ, Lammertsma AA. Effect of L-dopa and 6-hydroxydopamine lesioning on [11C]raclopride binding in rat striatum, quantified using PET. Synapse (New York, N.Y.). 21: 45-53. PMID 8525461 DOI: 10.1002/Syn.890210107  0.318
1995 Prevett MC, Lammertsma AA, Brooks DJ, Bartenstein PA, Patsalos PN, Fish DR, Duncan JS. Benzodiazepine-GABAA receptors in idiopathic generalized epilepsy measured with [11C]flumazenil and positron emission tomography. Epilepsia. 36: 113-21. PMID 7821267 DOI: 10.1111/J.1528-1157.1995.Tb00969.X  0.306
1995 Rinne JO, Burn DJ, Mathias CJ, Quinn NP, Marsden CD, Brooks DJ. Positron emission tomography studies on the dopaminergic system and striatal opioid binding in the olivopontocerebellar atrophy variant of multiple system atrophy Annals of Neurology. 37: 568-573. PMID 7755350 DOI: 10.1002/Ana.410370505  0.344
1995 Playford ED, Britton TC, Thompson PD, Brooks DJ, Findley LJ, Marsden CD. Exacerbation of postural tremor with emergence of parkinsonism after treatment with neuroleptic drugs. Journal of Neurology, Neurosurgery, and Psychiatry. 58: 487-489. PMID 7738563 DOI: 10.1136/Jnnp.58.4.487  0.346
1995 Brooks DJ. The role of the basal ganglia in motor control: contributions from PET Journal of the Neurological Sciences. 128: 1-13. PMID 7722526 DOI: 10.1016/0022-510X(94)00206-4  0.322
1995 Burn DJ, Rinne JO, Quinn NP, Lees AJ, Marsden CD, Brooks DJ. Striatal opioid receptor binding in Parkinson's disease, striatonigral degeneration and Steele-Richardson-Olszewski syndrome, A [11C]diprenorphine PET study. Brain. 118: 951-958. PMID 7655890 DOI: 10.1093/Brain/118.4.951  0.322
1995 Jahanshahi M, Jenkins IH, Brown RG, Marsden CD, Passingham RE, Brooks DJ. Self-initiated versus externally triggered movements. I. An investigation using measurement of regional cerebral blood flow with PET and movement-related potentials in normal and Parkinson's disease subjects. Brain : a Journal of Neurology. 118: 913-33. PMID 7655888 DOI: 10.1093/Brain/118.4.913  0.304
1995 Opacka-Juffry J, Brooks DJ. L-dihydroxyphenylalanine and its decarboxylase: new ideas on their neuroregulatory roles. Movement Disorders. 10: 241-249. PMID 7651438 DOI: 10.1002/Mds.870100302  0.314
1995 Abrahams S, Leigh PN, Kew JJM, Goldstein LH, Lloyd CML, Brooks DJ. A positron emission tomography study of frontal lobe function (verbal fluency) in amyotrophic lateral sclerosis Journal of the Neurological Sciences. 129: 44-46. PMID 7595618 DOI: 10.1016/0022-510X(95)00060-F  0.31
1995 Morrish PK, Sawle GV, Brooks DJ. Clinical and [18F] dopa PET findings in early Parkinson's disease. Journal of Neurology, Neurosurgery, and Psychiatry. 59: 597-600. PMID 7500096 DOI: 10.1136/Jnnp.59.6.597  0.358
1995 Dettmers C, Fink GR, Lemon RN, Stephan KM, Passingham RE, Silbersweig D, Holmes A, Ridding MC, Brooks DJ, Frackowiak RS. Relation between cerebral activity and force in the motor areas of the human brain. Journal of Neurophysiology. 74: 802-15. PMID 7472384 DOI: 10.1152/Jn.1995.74.2.802  0.309
1995 Opacka-Juffry J, Ashworth S, Hume SP, Martin D, Brooks DJ, Blunt SB. GDNF protects against 6-OHDA nigrostriatal lesion: in vivo study with microdialysis and PET. Neuroreport. 7: 348-352. DOI: 10.1097/00001756-199512000-00083  0.326
1994 Burn DJ, Sawle GV, Brooks DJ. Differential diagnosis of Parkinson's disease, multiple system atrophy, and Steele-Richardson-Olszewski syndrome: discriminant analysis of striatal 18F-dopa PET data. Journal of Neurology, Neurosurgery, and Psychiatry. 57: 278-284. PMID 8158173 DOI: 10.1136/Jnnp.57.3.278  0.374
1994 Sawle GV, Playford ED, Burn DJ, Cunningham VJ, Brooks DJ. Separating Parkinson's Disease From Normality: Discriminant Function Analysis of Fluorodopa F 18 Positron Emission Tomography Data Jama Neurology. 51: 237-243. PMID 8129633 DOI: 10.1001/Archneur.1994.00540150027011  0.365
1994 Sawle GV, Burn DJ, Morrish PK, Lammertsma AA, Snow BJ, Luthra S, Osman S, Brooks DJ. The effect of entacapone (OR-611) on brain [18F]-6-L-fluorodopa metabolism: implications for levodopa therapy of Parkinson's disease. Neurology. 44: 1292-7. PMID 8035933 DOI: 10.1212/Wnl.44.7.1292  0.302
1994 Ring HA, Bench CJ, Trimble MR, Brooks DJ, Frackowiak RS, Dolan RJ. Depression in Parkinson's disease. A positron emission study. The British Journal of Psychiatry : the Journal of Mental Science. 165: 333-9. PMID 7994502 DOI: 10.1192/Bjp.165.3.333  0.304
1994 Brooks DJ. PET studies in progressive supranuclear palsy Journal of Neural Transmission-Supplement. 42: 119-134. PMID 7964682 DOI: 10.1007/978-3-7091-6641-3_10  0.333
1994 Turjanski N, Sawle GV, Playford ED, Weeks R, Lammerstma AA, Lees AJ, Brooks DJ. PET studies of the presynaptic and postsynaptic dopaminergic system in Tourette's syndrome. Journal of Neurology, Neurosurgery, and Psychiatry. 57: 688-692. PMID 7911827 DOI: 10.1136/Jnnp.57.6.688  0.321
1994 Weeks R, Brooks D. Positron emission tomography and central neurotransmitter systems in movement disorders Fundamental & Clinical Pharmacology. 8: 503-517. PMID 7721227 DOI: 10.1111/J.1472-8206.1994.Tb00831.X  0.302
1994 Ring HA, Bench CJ, Trimble MR, Brooks DJ, Frackowiak RSJ, Dolan RJ. Depression in parkinson's disease: A pet study Biological Psychiatry. 35: 685-686. DOI: 10.1016/0006-3223(94)90912-1  0.305
1993 Jenkins IH, Bain PG, Colebatch JG, Thompson PD, Findley LJ, Frackowiak RS, Marsden CD, Brooks DJ. A positron emission tomography study of essential tremor: evidence for overactivity of cerebellar connections. Annals of Neurology. 34: 82-90. PMID 8517685 DOI: 10.1002/Ana.410340115  0.309
1993 Brooks DJ. Functional imaging in relation to parkinsonian syndromes. Journal of the Neurological Sciences. 115: 1-17. PMID 8468583 DOI: 10.1016/0022-510X(93)90061-3  0.354
1993 Burn DJ, Brooks DJ. Nigral dysfunction in drug‐induced parkinsonism An 18F‐dopa PET study Neurology. 43: 552-552. PMID 8451000 DOI: 10.1212/Wnl.43.3_Part_1.552  0.35
1993 Sawle GV, Playford ED, Brooks DJ, Quinn N, Frackowiak RS. Asymmetrical pre-synaptic and post-synpatic changes in the striatal dopamine projection in dopa naïve parkinsonism. Diagnostic implications of the D2 receptor status. Brain : a Journal of Neurology. 853-67. PMID 8353712 DOI: 10.1093/Brain/116.4.853  0.33
1993 Turjanski N, Bhatia K, Burn DJ, Sawle GV, Marsden CD, Brooks DJ. Comparison of striatal 18F‐dopa uptake in adult‐onset dystonia‐parkinsonism, Parkinson's disease, and dopa‐responsive dystonia Neurology. 43: 1563-1563. PMID 8351012 DOI: 10.1212/Wnl.43.8.1563  0.343
1993 Kew JJ, Goldstein LH, Leigh PN, Abrahams S, Cosgrave N, Passingham RE, Frackowiak RS, Brooks DJ. The relationship between abnormalities of cognitive function and cerebral activation in amyotrophic lateral sclerosis. A neuropsychological and positron emission tomography study. Brain : a Journal of Neurology. 116: 1399-423. PMID 8293278 DOI: 10.1093/Brain/116.6.1399  0.305
1993 Playford ED, Fletcher NA, Sawle GV, Marsden CD, Brooks DJ. Striatal [18F]dopa uptake in familial idiopathic dystonia. Brain. 116: 1191-1199. PMID 8221055 DOI: 10.1093/Brain/116.5.1191  0.315
1992 Brooks DJ, Playford ED, Ibanez V, Sawle GV, Thompson PD, Findley LJ, Marsden CD. Isolated tremor and disruption of the nigrostriatal dopaminergic system: an 18F-dopa PET study. Neurology. 42: 1554-1554. PMID 1641153 DOI: 10.1212/Wnl.42.8.1554  0.336
1992 Brooks DJ, Ibanez V, Sawle GV, Playford ED, Quinn N, Mathias CJ, Lees AJ, Marsden CD, Bannister R, Frackowiak RS. Striatal D2 receptor status in patients with Parkinson's disease, striatonigral degeneration, and progressive supranuclear palsy, measured with 11C-raclopride and positron emission tomography. Annals of Neurology. 31: 184-92. PMID 1575457 DOI: 10.1002/Ana.410310209  0.342
1992 Playford ED, Jenkins IH, Passingham RE, Nutt J, Frackowiak RS, Brooks DJ. Impaired mesial frontal and putamen activation in Parkinson's disease: a positron emission tomography study. Annals of Neurology. 32: 151-61. PMID 1510355 DOI: 10.1002/Ana.410320206  0.339
1992 Jenkins IH, Fernandez W, Playford ED, Lees AJ, Frackowiak RS, Passingham RE, Brooks DJ. Impaired activation of the supplementary motor area in Parkinson's disease is reversed when akinesia is treated with apomorphine. Annals of Neurology. 32: 749-57. PMID 1471865 DOI: 10.1002/Ana.410320608  0.341
1992 Sawle GV, Wroe SJ, Lees AJ, Brooks DJ, Frackowiak RS. The identification of presymptomatic parkinsonism: clinical and [18F]dopa positron emission tomography studies in an Irish kindred. Annals of Neurology. 32: 609-17. PMID 1449241 DOI: 10.1002/Ana.410320503  0.354
1992 Hume SP, Myers R, Bloomfield PM, Opacka-Juffry J, Cremer JE, Ahier RG, Luthra SK, Brooks DJ, Lammertsma AA. Quantitation of carbon-11-labeled raclopride in rat striatum using positron emission tomography. Synapse (New York, N.Y.). 12: 47-54. PMID 1411963 DOI: 10.1002/Syn.890120106  0.33
1992 Burn DJ, Mark MH, Playford ED, Maraganore DM, Zimmerman TR, Duvoisin RC, Harding AE, Marsden CD, Brooks DJ. Parkinson's disease in twins studied with 18F-dopa and positron emission tomography. Neurology. 42: 1894-900. PMID 1407569 DOI: 10.1212/Wnl.42.10.1894  0.344
1991 Brooks DJ, Ibanez V, Sawle GV, Quinn N, Lees AJ, Mathias CJ, Bannister R, Marsden CD, Frackowiak RS. Differing patterns of striatal 18F-dopa uptake in Parkinson's disease, multiple system atrophy, and progressive supranuclear palsy. Annals of Neurology. 28: 547-55. PMID 2132742 DOI: 10.1002/Ana.410280412  0.355
1991 Sawle GV, Colebatch JG, Shah A, Brooks DJ, Marsden CD, Frackowiak RS. Striatal function in normal aging: implications for Parkinson's disease. Annals of Neurology. 28: 799-804. PMID 2126684 DOI: 10.1002/Ana.410280611  0.345
1991 Leenders KL, Salmon EP, Tyrrell P, Perani D, Brooks DJ, Sager H, Jones T, Marsden CD, Frackowiak RS. The nigrostriatal dopaminergic system assessed in vivo by positron emission tomography in healthy volunteer subjects and patients with Parkinson's disease. Archives of Neurology. 47: 1290-8. PMID 2123623 DOI: 10.1001/Archneur.1990.00530120034007  0.384
1991 Brooks DJ, Salmon EP, Mathias CJ, Quinn N, Leenders KL, Bannister R, Marsden CD, Frackowiak RS. The relationship between locomotor disability, autonomic dysfunction, and the integrity of the striatal dopaminergic system in patients with multiple system atrophy, pure autonomic failure, and Parkinson's disease, studied with PET. Brain : a Journal of Neurology. 1539-52. PMID 2123119 DOI: 10.1093/Brain/113.5.1539  0.372
1991 Brooks DJ. Detection of preclinical Parkinson's disease with PET Neurology. 41: 24-27. PMID 1904139 DOI: 10.1212/Wnl.41.5_Suppl_2.24  0.359
1991 Sawle GV, Brooks DJ, Marsden CD, Frackowiak RS. Corticobasal degeneration. A unique pattern of regional cortical oxygen hypometabolism and striatal fluorodopa uptake demonstrated by positron emission tomography. Brain : a Journal of Neurology. 541-56. PMID 1900728 DOI: 10.1093/Brain/114.1.541  0.331
1991 Brooks DJ, Ibanez V, Playford ED, Sawle GV, Leigh PN, Kocen RS, Harding AE, Marchsden CD. Presynaptic and postsynaptic striatal dopaminergic function in neuroacanthocytosis: A positron emission tomographic study Annals of Neurology. 30: 166-171. PMID 1897909 DOI: 10.1002/Ana.410300207  0.366
1991 Sawle GV, Leenders KL, Brooks DJ, Harwood G, Lees AJ, Frackowiak RS, Marsden CD. Dopa-responsive dystonia: [18F]dopa positron emission tomography. Annals of Neurology. 30: 24-30. PMID 1681782 DOI: 10.1002/Ana.410300106  0.341
1991 Brooks DJ. Pet : Its Clinical Role In Neurology Journal of Neurology, Neurosurgery, and Psychiatry. 54: 1-5. PMID 1672706 DOI: 10.1136/Jnnp.54.1.1  0.302
1990 Salmon E, Brooks DJ, Leenders KL, Turton DR, Hume SP, Cremer JE, Jones T, Frackowiak RSJ. A two-compartment description and kinetic procedure for measuring regional cerebral [11C]nomifensine uptake using positron emission tomography Journal of Cerebral Blood Flow and Metabolism. 10: 307-316. PMID 2329119 DOI: 10.1038/Jcbfm.1990.59  0.328
1990 Sawle GV, Brooks DJ. Positron emission tomography studies of neurotransmitter systems Journal of Neurology. 237: 451-456. PMID 1981574 DOI: 10.1007/Bf00314760  0.317
1989 Leenders KL, Frackowiak RS, Quinn N, Brooks D, Sumner D, Marsden CD. Ipsilateral blepharospasm and contralateral hemidystonia and parkinsonism in a patient with a unilateral rostral brainstem-thalamic lesion: structural and functional abnormalities studied with CT, MRI, and PET scanning. Movement Disorders : Official Journal of the Movement Disorder Society. 1: 51-8. PMID 2973558 DOI: 10.1002/Mds.870010107  0.316
1989 Brooks D. Positron emission tomographic studies of the subcortical degenerations and dystonia. Seminars in Neurology. 9: 351-359. PMID 2701780 DOI: 10.1055/S-2008-1041345  0.328
1989 Brooks DJ, Frackowiak RSJ. PET and movement disorders. Journal of Neurology, Neurosurgery, and Psychiatry. 52: 68-77. PMID 2666580 DOI: 10.1136/Jnnp.52.Suppl.68  0.32
1984 Thomas DGT, Beaney RP, Brooks DJ. Positron emission tomography in the study of cerebral tumours Neurosurgical Review. 7: 253-258. PMID 6397696 DOI: 10.1007/Bf01892906  0.305
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