| Year |
Citation |
Score |
| 2021 |
Riboldi GM, Faravelli I, Kuwajima T, Delestrée N, Dermentzaki G, De Planell-Saguer M, Rinchetti P, Hao LT, Beattie CC, Corti S, Przedborski S, Mentis GZ, Lotti F. Sumoylation regulates the assembly and activity of the SMN complex. Nature Communications. 12: 5040. PMID 34413305 DOI: 10.1038/s41467-021-25272-5 |
0.732 |
|
| 2021 |
Van Harten ACM, Phatnani H, Przedborski S. Non-cell-autonomous pathogenic mechanisms in amyotrophic lateral sclerosis. Trends in Neurosciences. PMID 34006386 DOI: 10.1016/j.tins.2021.04.008 |
0.323 |
|
| 2020 |
Mishra V, Re DB, Le Verche V, Alvarez MJ, Vasciaveo A, Jacquier A, Doulias PT, Greco TM, Nizzardo M, Papadimitriou D, Nagata T, Rinchetti P, Perez-Torres EJ, Politi KA, Ikiz B, ... ... Przedborski S, et al. Systematic elucidation of neuron-astrocyte interaction in models of amyotrophic lateral sclerosis using multi-modal integrated bioinformatics workflow. Nature Communications. 11: 5579. PMID 33149111 DOI: 10.1038/s41467-020-19177-y |
0.784 |
|
| 2019 |
Ji R, Smith M, Niimi Y, Karakatsani ME, Murillo MF, Jackson-Lewis V, Przedborski S, Konofagou EE. Focused ultrasound enhanced intranasal delivery of brain derived neurotrophic factor produces neurorestorative effects in a Parkinson's disease mouse model. Scientific Reports. 9: 19402. PMID 31852909 DOI: 10.1038/S41598-019-55294-5 |
0.387 |
|
| 2019 |
Karakatsani ME, Wang S, Samiotaki G, Kugelman T, Olumolade OO, Acosta C, Sun T, Han Y, Kamimura HAS, Jackson-Lewis V, Przedborski S, Konofagou E. Amelioration of the nigrostriatal pathway facilitated by ultrasound-mediated neurotrophic delivery in early Parkinson's disease. Journal of Controlled Release : Official Journal of the Controlled Release Society. PMID 30953664 DOI: 10.1016/J.Jconrel.2019.03.030 |
0.403 |
|
| 2019 |
Area-Gomez E, Guardia-Laguarta C, Schon EA, Przedborski S. Mitochondria, OxPhos, and neurodegeneration: cells are not just running out of gas. The Journal of Clinical Investigation. 129: 34-45. PMID 30601141 DOI: 10.1172/Jci120848 |
0.359 |
|
| 2018 |
Antoniou N, Vlachakis D, Memou A, Leandrou E, Valkimadi PE, Melachroinou K, Re DB, Przedborski S, Dauer WT, Stefanis L, Rideout HJ. A motif within the armadillo repeat of Parkinson's-linked LRRK2 interacts with FADD to hijack the extrinsic death pathway. Scientific Reports. 8: 3455. PMID 29472595 DOI: 10.1038/S41598-018-21931-8 |
0.394 |
|
| 2018 |
Steinkellner T, Zell V, Farino ZJ, Sonders MS, Villeneuve M, Freyberg RJ, Przedborski S, Lu W, Freyberg Z, Hnasko TS. Role for VGLUT2 in selective vulnerability of midbrain dopamine neurons. The Journal of Clinical Investigation. PMID 29337309 DOI: 10.1172/Jci95795 |
0.366 |
|
| 2017 |
Obeso JA, Stamelou M, Goetz CG, Poewe W, Lang AE, Weintraub D, Burn D, Halliday GM, Bezard E, Przedborski S, Lehericy S, Brooks DJ, Rothwell JC, Hallett M, DeLong MR, et al. Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy. Movement Disorders : Official Journal of the Movement Disorder Society. 32: 1264-1310. PMID 28887905 DOI: 10.1002/Mds.27115 |
0.552 |
|
| 2017 |
Przedborski S. The two-century journey of Parkinson disease research. Nature Reviews. Neuroscience. 18: 251-259. PMID 28303016 DOI: 10.1038/Nrn.2017.25 |
0.378 |
|
| 2017 |
Zhang H, Sanchez CS, Kwon N, Jackson-Lewis VR, Przedborski S, Konofagou E. Focused-ultrasound mediated anti-alpha-synuclein antibody delivery for the treatment of Parkinson’s disease The Journal of the Acoustical Society of America. 142: 2721-2721. DOI: 10.1121/1.5014928 |
0.38 |
|
| 2016 |
Hasegawa K, Yasuda T, Shiraishi C, Fujiwara K, Przedborski S, Mochizuki H, Yoshikawa K. Promotion of mitochondrial biogenesis by necdin protects neurons against mitochondrial insults. Nature Communications. 7: 10943. PMID 26971449 DOI: 10.1038/Ncomms10943 |
0.364 |
|
| 2015 |
Brichta L, Shin W, Jackson-Lewis V, Blesa J, Yap EL, Walker Z, Zhang J, Roussarie JP, Alvarez MJ, Califano A, Przedborski S, Greengard P. Identification of neurodegenerative factors using translatome-regulatory network analysis. Nature Neuroscience. PMID 26214373 DOI: 10.1038/Nn.4070 |
0.377 |
|
| 2015 |
Ikiz B, Alvarez MJ, Ré DB, Le Verche V, Politi K, Lotti F, Phani S, Pradhan R, Yu C, Croft GF, Jacquier A, Henderson CE, Califano A, Przedborski S. The Regulatory Machinery of Neurodegeneration in In Vitro Models of Amyotrophic Lateral Sclerosis. Cell Reports. 12: 335-45. PMID 26146077 DOI: 10.1016/J.Celrep.2015.06.019 |
0.786 |
|
| 2015 |
Dehay B, Bourdenx M, Gorry P, Przedborski S, Vila M, Hunot S, Singleton A, Olanow CW, Merchant KM, Bezard E, Petsko GA, Meissner WG. Targeting α-synuclein for treatment of Parkinson's disease: mechanistic and therapeutic considerations. The Lancet. Neurology. PMID 26050140 DOI: 10.1016/S1474-4422(15)00006-X |
0.78 |
|
| 2015 |
Kett LR, Stiller B, Bernath MM, Tasset I, Blesa J, Jackson-Lewis V, Chan RB, Zhou B, Di Paolo G, Przedborski S, Cuervo AM, Dauer WT. α-Synuclein-independent histopathological and motor deficits in mice lacking the endolysosomal Parkinsonism protein Atp13a2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 5724-42. PMID 25855184 DOI: 10.1523/Jneurosci.0632-14.2015 |
0.589 |
|
| 2015 |
Konofagou E, Samiotaki G, Wang S, Jackson-Lewis V, Przedborski S. Neuroprotection and neuroregeneration triggered through the FUS-induced opening of the blood-brain barrier in a Parkinson’s mouse model Journal of Therapeutic Ultrasound. 3. DOI: 10.1186/2050-5736-3-S1-O19 |
0.352 |
|
| 2014 |
Blesa J, Przedborski S. Parkinson's disease: animal models and dopaminergic cell vulnerability. Frontiers in Neuroanatomy. 8: 155. PMID 25565980 DOI: 10.3389/Fnana.2014.00155 |
0.419 |
|
| 2014 |
Le Masson G, Przedborski S, Abbott LF. A computational model of motor neuron degeneration. Neuron. 83: 975-88. PMID 25088365 DOI: 10.1016/J.Neuron.2014.07.001 |
0.359 |
|
| 2014 |
Re DB, Le Verche V, Yu C, Amoroso MW, Politi KA, Phani S, Ikiz B, Hoffmann L, Koolen M, Nagata T, Papadimitriou D, Nagy P, Mitsumoto H, Kariya S, Wichterle H, ... ... Przedborski S, et al. Necroptosis drives motor neuron death in models of both sporadic and familial ALS. Neuron. 81: 1001-8. PMID 24508385 DOI: 10.1016/J.Neuron.2014.01.011 |
0.789 |
|
| 2014 |
Ikiz B, Alvarez MJ, Ré DB, LeVerche V, Politi K, Lotti F, Phani S, Pradhan R, Yu C, Croft GF, Jacquier A, Henderson CE, Califano A, Przedborski S. The Regulatory Machinery of Neurodegeneration in InVitro Models of Amyotrophic Lateral Sclerosis Cell Reports. DOI: 10.1016/j.celrep.2015.06.019 |
0.759 |
|
| 2013 |
Roybon L, Lamas NJ, Garcia-Diaz A, Yang EJ, Sattler R, Jackson-Lewis V, Kim YA, Kachel CA, Rothstein JD, Przedborski S, Wichterle H, Henderson CE. Human stem cell-derived spinal cord astrocytes with defined mature or reactive phenotypes. Cell Reports. 4: 1035-48. PMID 23994478 DOI: 10.1016/J.Celrep.2013.06.021 |
0.448 |
|
| 2013 |
Ravits J, Appel S, Baloh RH, Barohn R, Brooks BR, Elman L, Floeter MK, Henderson C, Lomen-Hoerth C, Macklis JD, McCluskey L, Mitsumoto H, Przedborski S, Rothstein J, Trojanowski JQ, et al. Deciphering amyotrophic lateral sclerosis: what phenotype, neuropathology and genetics are telling us about pathogenesis. Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration. 14: 5-18. PMID 23678876 DOI: 10.3109/21678421.2013.778548 |
0.596 |
|
| 2013 |
Hirsch EC, Jenner P, Przedborski S. Pathogenesis of Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 28: 24-30. PMID 22927094 DOI: 10.1002/Mds.25032 |
0.4 |
|
| 2012 |
Klionsky DJ, Abdalla FC, Abeliovich H, Abraham RT, Acevedo-Arozena A, Adeli K, Agholme L, Agnello M, Agostinis P, Aguirre-Ghiso JA, Ahn HJ, Ait-Mohamed O, Ait-Si-Ali S, Akematsu T, Akira S, ... ... Przedborski S, et al. Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy. 8: 445-544. PMID 22966490 DOI: 10.4161/Auto.19496 |
0.66 |
|
| 2012 |
Phani S, Re DB, Przedborski S. The Role of the Innate Immune System in ALS. Frontiers in Pharmacology. 3: 150. PMID 22912616 DOI: 10.3389/Fphar.2012.00150 |
0.444 |
|
| 2012 |
Gonzalez-Reyes LE, Verbitsky M, Blesa J, Jackson-Lewis V, Paredes D, Tillack K, Phani S, Kramer ER, Przedborski S, Kottmann AH. Sonic hedgehog maintains cellular and neurochemical homeostasis in the adult nigrostriatal circuit. Neuron. 75: 306-19. PMID 22841315 DOI: 10.1016/J.Neuron.2012.05.018 |
0.306 |
|
| 2012 |
Kariya S, Re DB, Jacquier A, Nelson K, Przedborski S, Monani UR. Mutant superoxide dismutase 1 (SOD1), a cause of amyotrophic lateral sclerosis, disrupts the recruitment of SMN, the spinal muscular atrophy protein to nuclear cajal bodies Human Molecular Genetics. 21: 3421-3434. PMID 22581780 DOI: 10.1093/hmg/dds174 |
0.316 |
|
| 2012 |
Blesa J, Phani S, Jackson-Lewis V, Przedborski S. Classic and new animal models of Parkinson's disease. Journal of Biomedicine & Biotechnology. 2012: 845618. PMID 22536024 DOI: 10.1155/2012/845618 |
0.394 |
|
| 2012 |
Phani S, Loike JD, Przedborski S. Neurodegeneration and inflammation in Parkinson's disease. Parkinsonism & Related Disorders. 18: S207-9. PMID 22166436 DOI: 10.1016/S1353-8020(11)70064-5 |
0.425 |
|
| 2012 |
Jackson-Lewis V, Blesa J, Przedborski S. Animal models of Parkinson's disease. Parkinsonism & Related Disorders. 18: S183-5. PMID 22166429 DOI: 10.1016/S1353-8020(11)70057-8 |
0.357 |
|
| 2012 |
Lim L, Jackson-Lewis V, Wong LC, Shui GH, Goh AX, Kesavapany S, Jenner AM, Fivaz M, Przedborski S, Wenk MR. Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease. Cell Death and Differentiation. 19: 416-27. PMID 21818119 DOI: 10.1038/cdd.2011.105 |
0.339 |
|
| 2012 |
Lim S, Chesser A, Grima J, Rappold P, Blum D, Przedborski S, Tieu K. 3.260 D-β-HYDROXYBUTYRATE IS NEUROPROTECTIVE IN MOUSE MODELS OF HUNTINGTON'S DISEASE Parkinsonism & Related Disorders. 18: S218. DOI: 10.1016/S1353-8020(11)70931-2 |
0.303 |
|
| 2012 |
Yasuda T, Yoshikawa K, Przedborski S, Mizuno Y, Mochizuki H. 3.205 Necdin Prevents Loss Of Dopaminergic Neurons In Animal Models Of Parkinson'S Disease Parkinsonism & Related Disorders. 18. DOI: 10.1016/S1353-8020(11)70878-1 |
0.428 |
|
| 2011 |
Lim S, Chesser AS, Grima JC, Rappold PM, Blum D, Przedborski S, Tieu K. D-β-hydroxybutyrate is protective in mouse models of Huntington's disease. Plos One. 6: e24620. PMID 21931779 DOI: 10.1371/Journal.Pone.0024620 |
0.374 |
|
| 2011 |
Bezard E, Przedborski S. A tale on animal models of Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 26: 993-1002. PMID 21626544 DOI: 10.1002/Mds.23696 |
0.582 |
|
| 2011 |
Vives-Bauza C, Przedborski S. Mitophagy: the latest problem for Parkinson's disease. Trends in Molecular Medicine. 17: 158-65. PMID 21146459 DOI: 10.1016/J.Molmed.2010.11.002 |
0.385 |
|
| 2011 |
Zhang W, Phillips K, Wielgus AR, Liu J, Albertini A, Zucca FA, Faust R, Qian SY, Miller DS, Chignell CF, Wilson B, Jackson-Lewis V, Przedborski S, Joset D, Loike J, et al. Neuromelanin activates microglia and induces degeneration of dopaminergic neurons: implications for progression of Parkinson's disease. Neurotoxicity Research. 19: 63-72. PMID 19957214 DOI: 10.1007/S12640-009-9140-Z |
0.411 |
|
| 2011 |
le Verche V, Ikiz B, Jacquier A, Przedborski S, Re DB. Glutamate pathway implication in amyotrophic lateral sclerosis: What is the signal in the noise? Journal of Receptor, Ligand and Channel Research. 4: 1-22. DOI: 10.2147/JRLCR.S6504 |
0.74 |
|
| 2011 |
Przedborski S. Can a defect in bioenergetics be involved in the pathogenesis of Parkinson's disease after all?† Movement Disorders. 26: 1408-1408. DOI: 10.1002/Mds.23857 |
0.357 |
|
| 2010 |
Le Verche V, Przedborski S. Is amyotrophic lateral sclerosis a mitochondrial channelopathy? Neuron. 67: 523-4. PMID 20797528 DOI: 10.1016/J.Neuron.2010.08.010 |
0.397 |
|
| 2010 |
Vives-Bauza C, Tocilescu M, Devries RL, Alessi DM, Jackson-Lewis V, Przedborski S. Control of mitochondrial integrity in Parkinson's disease. Progress in Brain Research. 183: 99-113. PMID 20696317 DOI: 10.1016/S0079-6123(10)83006-7 |
0.377 |
|
| 2010 |
Perier C, Bové J, Dehay B, Jackson-Lewis V, Rabinovitch PS, Przedborski S, Vila M. Apoptosis-inducing factor deficiency sensitizes dopaminergic neurons to parkinsonian neurotoxins. Annals of Neurology. 68: 184-92. PMID 20695011 DOI: 10.1002/Ana.22034 |
0.64 |
|
| 2010 |
Vives-Bauza C, Przedborski S. PINK1 points Parkin to mitochondria. Autophagy. 6: 674-5. PMID 20484984 DOI: 10.4161/Auto.6.5.12068 |
0.359 |
|
| 2010 |
Przedborski S. Inflammation and Parkinson's disease pathogenesis. Movement Disorders : Official Journal of the Movement Disorder Society. 25: S55-7. PMID 20187228 DOI: 10.1002/Mds.22638 |
0.372 |
|
| 2010 |
Malagelada C, Jin ZH, Jackson-Lewis V, Przedborski S, Greene LA. Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 1166-75. PMID 20089925 DOI: 10.1523/JNEUROSCI.3944-09.2010 |
0.317 |
|
| 2010 |
Vives-Bauza C, Zhou C, Huang Y, Cui M, de Vries RL, Kim J, May J, Tocilescu MA, Liu W, Ko HS, Magrané J, Moore DJ, Dawson VL, Grailhe R, Dawson TM, ... ... Przedborski S, et al. PINK1-dependent recruitment of Parkin to mitochondria in mitophagy. Proceedings of the National Academy of Sciences of the United States of America. 107: 378-83. PMID 19966284 DOI: 10.1073/Pnas.0911187107 |
0.316 |
|
| 2010 |
Papadimitriou D, Le Verche V, Jacquier A, Ikiz B, Przedborski S, Re DB. Inflammation in ALS and SMA: Sorting out the good from the evil Neurobiology of Disease. 37: 493-502. PMID 19833209 DOI: 10.1016/J.Nbd.2009.10.005 |
0.776 |
|
| 2009 |
Vives-Bauza C, de Vries RL, Tocilescu MA, Przedborski S. Is there a pathogenic role for mitochondria in Parkinson's disease? Parkinsonism & Related Disorders. 15: S241-4. PMID 20083000 DOI: 10.1016/S1353-8020(09)70823-5 |
0.365 |
|
| 2009 |
Hoang T, Choi DK, Nagai M, Wu DC, Nagata T, Prou D, Wilson GL, Vila M, Jackson-Lewis V, Dawson VL, Dawson TM, Chesselet MF, Przedborski S. Neuronal NOS and cyclooxygenase-2 contribute to DNA damage in a mouse model of Parkinson disease. Free Radical Biology & Medicine. 47: 1049-56. PMID 19616617 DOI: 10.1016/J.Freeradbiomed.2009.07.013 |
0.389 |
|
| 2009 |
Li Y, Liu W, Oo TF, Wang L, Tang Y, Jackson-Lewis V, Zhou C, Geghman K, Bogdanov M, Przedborski S, Beal MF, Burke RE, Li C. Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease. Nature Neuroscience. 12: 826-8. PMID 19503083 DOI: 10.1038/Nn.2349 |
0.397 |
|
| 2009 |
Cui M, Aras R, Christian WV, Rappold PM, Hatwar M, Panza J, Jackson-Lewis V, Javitch JA, Ballatori N, Przedborski S, Tieu K. The organic cation transporter-3 is a pivotal modulator of neurodegeneration in the nigrostriatal dopaminergic pathway. Proceedings of the National Academy of Sciences of the United States of America. 106: 8043-8. PMID 19416912 DOI: 10.1073/Pnas.0900358106 |
0.375 |
|
| 2009 |
Zhou C, Przedborski S. Intrabody and Parkinson's disease. Biochimica Et Biophysica Acta. 1792: 634-42. PMID 18834937 DOI: 10.1016/J.Bbadis.2008.09.001 |
0.366 |
|
| 2008 |
Ikiz B, Przedborski S. A sequel to the tale of p25/Cdk5 in neurodegeneration. Neuron. 60: 731-2. PMID 19081365 DOI: 10.1016/J.Neuron.2008.11.020 |
0.767 |
|
| 2008 |
Zhou C, Huang Y, Przedborski S. Oxidative stress in Parkinson's disease: a mechanism of pathogenic and therapeutic significance. Annals of the New York Academy of Sciences. 1147: 93-104. PMID 19076434 DOI: 10.1196/Annals.1427.023 |
0.431 |
|
| 2008 |
Zhou C, Huang Y, Shao Y, May J, Prou D, Perier C, Dauer W, Schon EA, Przedborski S. The kinase domain of mitochondrial PINK1 faces the cytoplasm. Proceedings of the National Academy of Sciences of the United States of America. 105: 12022-7. PMID 18687899 DOI: 10.1073/Pnas.0802814105 |
0.345 |
|
| 2008 |
Banerjee R, Mosley RL, Reynolds AD, Dhar A, Jackson-Lewis V, Gordon PH, Przedborski S, Gendelman HE. Adaptive immune neuroprotection in G93A-SOD1 amyotrophic lateral sclerosis mice. Plos One. 3: e2740. PMID 18648532 DOI: 10.1371/Journal.Pone.0002740 |
0.315 |
|
| 2008 |
Martinez-Vicente M, Talloczy Z, Kaushik S, Massey AC, Mazzulli J, Mosharov EV, Hodara R, Fredenburg R, Wu DC, Follenzi A, Dauer W, Przedborski S, Ischiropoulos H, Lansbury PT, Sulzer D, et al. Dopamine-modified alpha-synuclein blocks chaperone-mediated autophagy. The Journal of Clinical Investigation. 118: 777-88. PMID 18172548 DOI: 10.1172/Jci32806 |
0.543 |
|
| 2008 |
Benner EJ, Banerjee R, Reynolds AD, Sherman S, Pisarev VM, Tsiperson V, Nemachek C, Ciborowski P, Przedborski S, Mosley RL, Gendelman HE. Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons. Plos One. 3: e1376. PMID 18167537 DOI: 10.1371/Journal.Pone.0001376 |
0.358 |
|
| 2007 |
Przedborski S. Neuroinflammation and Parkinson's disease. Handbook of Clinical Neurology. 83: 535-51. PMID 18808933 DOI: 10.1016/S0072-9752(07)83026-0 |
0.398 |
|
| 2007 |
Andres-Mateos E, Perier C, Zhang L, Blanchard-Fillion B, Greco TM, Thomas B, Ko HS, Sasaki M, Ischiropoulos H, Przedborski S, Dawson TM, Dawson VL. DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase. Proceedings of the National Academy of Sciences of the United States of America. 104: 14807-12. PMID 17766438 DOI: 10.1073/Pnas.0703219104 |
0.347 |
|
| 2007 |
Perier C, Bové J, Wu DC, Dehay B, Choi DK, Jackson-Lewis V, Rathke-Hartlieb S, Bouillet P, Strasser A, Schulz JB, Przedborski S, Vila M. Two molecular pathways initiate mitochondria-dependent dopaminergic neurodegeneration in experimental Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 104: 8161-6. PMID 17483459 DOI: 10.1073/Pnas.0609874104 |
0.667 |
|
| 2007 |
Nagai M, Re DB, Nagata T, Chalazonitis A, Jessell TM, Wichterle H, Przedborski S. Astrocytes expressing ALS-linked mutated SOD1 release factors selectively toxic to motor neurons. Nature Neuroscience. 10: 615-22. PMID 17435755 DOI: 10.1038/Nn1876 |
0.408 |
|
| 2007 |
Jackson-Lewis V, Przedborski S. Protocol for the MPTP mouse model of Parkinson's disease. Nature Protocols. 2: 141-51. PMID 17401348 DOI: 10.1038/Nprot.2006.342 |
0.374 |
|
| 2007 |
Whittle AJ, Ross OA, Naini A, Gordon P, Mistumoto H, Dächsel JC, Stone JT, Wszolek ZK, Farrer MJ, Przedborski S. Pathogenic Lrrk2 substitutions and Amyotrophic lateral sclerosis. Journal of Neural Transmission (Vienna, Austria : 1996). 114: 327-9. PMID 16865326 DOI: 10.1007/S00702-006-0525-3 |
0.351 |
|
| 2006 |
Dhib-Jalbut S, Arnold DL, Cleveland DW, Fisher M, Friedlander RM, Mouradian MM, Przedborski S, Trapp BD, Wyss-Coray T, Yong VW. Neurodegeneration and neuroprotection in multiple sclerosis and other neurodegenerative diseases. Journal of Neuroimmunology. 176: 198-215. PMID 16983747 DOI: 10.1016/J.Jneuroim.2006.03.027 |
0.471 |
|
| 2006 |
Mosharov EV, Staal RG, Bové J, Prou D, Hananiya A, Markov D, Poulsen N, Larsen KE, Moore CM, Troyer MD, Edwards RH, Przedborski S, Sulzer D. Alpha-synuclein overexpression increases cytosolic catecholamine concentration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 9304-11. PMID 16957086 DOI: 10.1523/Jneurosci.0519-06.2006 |
0.338 |
|
| 2006 |
Wu DC, Ré DB, Nagai M, Ischiropoulos H, Przedborski S. The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice. Proceedings of the National Academy of Sciences of the United States of America. 103: 12132-7. PMID 16877542 DOI: 10.1073/Pnas.0603670103 |
0.41 |
|
| 2006 |
Bové J, Zhou C, Jackson-Lewis V, Taylor J, Chu Y, Rideout HJ, Wu DC, Kordower JH, Petrucelli L, Przedborski S. Proteasome inhibition and Parkinson's disease modeling. Annals of Neurology. 60: 260-4. PMID 16862585 DOI: 10.1002/Ana.20937 |
0.359 |
|
| 2006 |
Ré DB, Przedborski S. Fractalkine: moving from chemotaxis to neuroprotection. Nature Neuroscience. 9: 859-61. PMID 16801915 DOI: 10.1038/Nn0706-859 |
0.362 |
|
| 2006 |
Kikuchi H, Almer G, Yamashita S, Guégan C, Nagai M, Xu Z, Sosunov AA, McKhann GM, Przedborski S. Spinal cord endoplasmic reticulum stress associated with a microsomal accumulation of mutant superoxide dismutase-1 in an ALS model. Proceedings of the National Academy of Sciences of the United States of America. 103: 6025-30. PMID 16595634 DOI: 10.1073/Pnas.0509227103 |
0.385 |
|
| 2006 |
Przedborski S, Vila M. The 1‐Methyl‐4‐Phenyl‐1,2,3,6‐Tetrahydropyridine Mouse Model Annals of the New York Academy of Sciences. 991: 189-198. DOI: 10.1111/J.1749-6632.2003.Tb07476.X |
0.416 |
|
| 2005 |
Bové J, Prou D, Perier C, Przedborski S. Toxin-induced models of Parkinson's disease. Neurorx : the Journal of the American Society For Experimental Neurotherapeutics. 2: 484-94. PMID 16389312 DOI: 10.1602/Neurorx.2.3.484 |
0.417 |
|
| 2005 |
Perier C, Tieu K, Guégan C, Caspersen C, Jackson-Lewis V, Carelli V, Martinuzzi A, Hirano M, Przedborski S, Vila M. Complex I deficiency primes Bax-dependent neuronal apoptosis through mitochondrial oxidative damage. Proceedings of the National Academy of Sciences of the United States of America. 102: 19126-31. PMID 16365298 DOI: 10.1073/Pnas.0508215102 |
0.348 |
|
| 2005 |
Li X, Rowland LP, Mitsumoto H, Przedborski S, Bird TD, Schellenberg GD, Peskind E, Johnson N, Siddique T, Mesulam MM, Weintraub S, Mastrianni JA. Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia. Annals of Neurology. 58: 858-64. PMID 16315279 DOI: 10.1002/Ana.20646 |
0.345 |
|
| 2005 |
Silva RM, Ries V, Oo TF, Yarygina O, Jackson-Lewis V, Ryu EJ, Lu PD, Marciniak SJ, Ron D, Przedborski S, Kholodilov N, Greene LA, Burke RE. CHOP/GADD153 is a mediator of apoptotic death in substantia nigra dopamine neurons in an in vivo neurotoxin model of parkinsonism. Journal of Neurochemistry. 95: 974-86. PMID 16135078 DOI: 10.1111/J.1471-4159.2005.03428.X |
0.442 |
|
| 2005 |
Choi DK, Pennathur S, Perier C, Tieu K, Teismann P, Wu DC, Jackson-Lewis V, Vila M, Vonsattel JP, Heinecke JW, Przedborski S. Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 6594-600. PMID 16014720 DOI: 10.1523/Jneurosci.0970-05.2005 |
0.41 |
|
| 2005 |
Przedborski S, Ischiropoulos H. Reactive oxygen and nitrogen species: weapons of neuronal destruction in models of Parkinson's disease. Antioxidants & Redox Signaling. 7: 685-93. PMID 15890013 DOI: 10.1089/Ars.2005.7.685 |
0.442 |
|
| 2005 |
Przedborski S. Pathogenesis of nigral cell death in Parkinson's disease. Parkinsonism & Related Disorders. 11: S3-7. PMID 15885625 DOI: 10.1016/J.Parkreldis.2004.10.012 |
0.436 |
|
| 2005 |
Eriksen JL, Przedborski S, Petrucelli L. Gene dosage and pathogenesis of Parkinson's disease. Trends in Molecular Medicine. 11: 91-6. PMID 15760766 DOI: 10.1016/J.Molmed.2005.01.001 |
0.34 |
|
| 2004 |
Przedborski S. Molecular targets for neuroprotection. Amyotrophic Lateral Sclerosis and Other Motor Neuron Disorders : Official Publication of the World Federation of Neurology, Research Group On Motor Neuron Diseases. 5: 14-8. PMID 15512862 DOI: 10.1080/1734470410019780 |
0.383 |
|
| 2004 |
Przedborski S, Tieu K, Perier C, Vila M. MPTP as a mitochondrial neurotoxic model of Parkinson's disease. Journal of Bioenergetics and Biomembranes. 36: 375-9. PMID 15377875 DOI: 10.1023/B:Jobb.0000041771.66775.D5 |
0.428 |
|
| 2004 |
Tieu K, Perier C, Vila M, Caspersen C, Zhang HP, Teismann P, Jackson-Lewis V, Stern DM, Yan SD, Przedborski S. L-3-hydroxyacyl-CoA dehydrogenase II protects in a model of Parkinson's disease. Annals of Neurology. 56: 51-60. PMID 15236401 DOI: 10.1002/Ana.20133 |
0.382 |
|
| 2004 |
Benner EJ, Mosley RL, Destache CJ, Lewis TB, Jackson-Lewis V, Gorantla S, Nemachek C, Green SR, Przedborski S, Gendelman HE. Therapeutic immunization protects dopaminergic neurons in a mouse model of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 101: 9435-40. PMID 15197276 DOI: 10.1073/Pnas.0400569101 |
0.418 |
|
| 2004 |
Hayley S, Crocker SJ, Smith PD, Shree T, Jackson-Lewis V, Przedborski S, Mount M, Slack R, Anisman H, Park DS. Regulation of dopaminergic loss by Fas in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2045-53. PMID 14985447 DOI: 10.1523/Jneurosci.4564-03.2004 |
0.425 |
|
| 2004 |
Przedborski S. Clarification: Pathogenic role of glial cells in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 19: 118. PMID 14743378 DOI: 10.1002/Mds.10701 |
0.322 |
|
| 2004 |
Przedborski S. Programmed cell death in amyotrophic lateral sclerosis: a mechanism of pathogenic and therapeutic importance. The Neurologist. 10: 1-7. PMID 14720310 DOI: 10.1097/01.Nrl.0000106920.84668.37 |
0.392 |
|
| 2004 |
Hunot S, Vila M, Teismann P, Davis RJ, Hirsch EC, Przedborski S, Rakic P, Flavell RA. JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 101: 665-70. PMID 14704277 DOI: 10.1073/Pnas.0307453101 |
0.434 |
|
| 2003 |
Bezard E, Dovero S, Belin D, Duconger S, Jackson-Lewis V, Przedborski S, Piazza PV, Gross CE, Jaber M. Enriched environment confers resistance to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and cocaine: involvement of dopamine transporter and trophic factors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 10999-1007. PMID 14657156 DOI: 10.1523/Jneurosci.23-35-10999.2003 |
0.467 |
|
| 2003 |
Zhang Y, Ona VO, Li M, Drozda M, Dubois-Dauphin M, Przedborski S, Ferrante RJ, Friedlander RM. Sequential activation of individual caspases, and of alterations in Bcl-2 proapoptotic signals in a mouse model of Huntington's disease. Journal of Neurochemistry. 87: 1184-92. PMID 14622098 DOI: 10.1046/J.1471-4159.2003.02105.X |
0.344 |
|
| 2003 |
Smith PD, Crocker SJ, Jackson-Lewis V, Jordan-Sciutto KL, Hayley S, Mount MP, O'Hare MJ, Callaghan S, Slack RS, Przedborski S, Anisman H, Park DS. Cyclin-dependent kinase 5 is a mediator of dopaminergic neuron loss in a mouse model of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 100: 13650-5. PMID 14595022 DOI: 10.1073/Pnas.2232515100 |
0.411 |
|
| 2003 |
Tieu K, Perier C, Caspersen C, Teismann P, Wu DC, Yan SD, Naini A, Vila M, Jackson-Lewis V, Ramasamy R, Przedborski S. D-beta-hydroxybutyrate rescues mitochondrial respiration and mitigates features of Parkinson disease. The Journal of Clinical Investigation. 112: 892-901. PMID 12975474 DOI: 10.1172/Jci18797 |
0.402 |
|
| 2003 |
Dauer W, Przedborski S. Parkinson's disease: mechanisms and models. Neuron. 39: 889-909. PMID 12971891 DOI: 10.1016/S0896-6273(03)00568-3 |
0.432 |
|
| 2003 |
Perier C, Bové J, Vila M, Przedborski S. The rotenone model of Parkinson's disease. Trends in Neurosciences. 26: 345-6. PMID 12850429 DOI: 10.1016/S0166-2236(03)00144-9 |
0.356 |
|
| 2003 |
Teismann P, Vila M, Choi DK, Tieu K, Wu DC, Jackson-Lewis V, Przedborski S. COX-2 and neurodegeneration in Parkinson's disease Annals of the New York Academy of Sciences. 991: 272-277. PMID 12846993 DOI: 10.1111/J.1749-6632.2003.Tb07482.X |
0.428 |
|
| 2003 |
Przedborski S, Vila M. The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model: a tool to explore the pathogenesis of Parkinson's disease. Annals of the New York Academy of Sciences. 991: 189-98. PMID 12846987 |
0.312 |
|
| 2003 |
Crocker SJ, Smith PD, Jackson-Lewis V, Lamba WR, Hayley SP, Grimm E, Callaghan SM, Slack RS, Melloni E, Przedborski S, Robertson GS, Anisman H, Merali Z, Park DS. Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4081-91. PMID 12764095 DOI: 10.1523/Jneurosci.23-10-04081.2003 |
0.434 |
|
| 2003 |
Vila M, Przedborski S. Targeting programmed cell death in neurodegenerative diseases. Nature Reviews. Neuroscience. 4: 365-75. PMID 12728264 DOI: 10.1038/Nrn1100 |
0.4 |
|
| 2003 |
Wu DC, Teismann P, Tieu K, Vila M, Jackson-Lewis V, Ischiropoulos H, Przedborski S. NADPH oxidase mediates oxidative stress in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. 100: 6145-50. PMID 12721370 DOI: 10.1073/Pnas.0937239100 |
0.413 |
|
| 2003 |
Teismann P, Tieu K, Choi DK, Wu DC, Naini A, Hunot S, Vila M, Jackson-Lewis V, Przedborski S. Cyclooxygenase-2 is instrumental in Parkinson's disease neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. 100: 5473-8. PMID 12702778 DOI: 10.1073/Pnas.0837397100 |
0.422 |
|
| 2003 |
Teismann P, Tieu K, Cohen O, Choi DK, Wu DC, Marks D, Vila M, Jackson-Lewis V, Przedborski S. Pathogenic role of glial cells in Parkinson's disease. Movement Disorders : Official Journal of the Movement Disorder Society. 18: 121-9. PMID 12539204 DOI: 10.1002/Mds.10332 |
0.431 |
|
| 2003 |
Guégan C, Przedborski S. Programmed cell death in amyotrophic lateral sclerosis Journal of Clinical Investigation. 111: 153-161. PMID 12531867 DOI: 10.1172/Jci17610 |
0.427 |
|
| 2003 |
Przedborski S, Vila M, Jackson-Lewis V. Neurodegeneration: What is it and where are we? Journal of Clinical Investigation. 111: 3-10. PMID 12511579 DOI: 10.1172/Jci17522 |
0.441 |
|
| 2003 |
Przedborski S, Mitsumoto H, Rowland LP. Recent advances in amyotrophic lateral sclerosis research. Current Neurology and Neuroscience Reports. 3: 70-7. PMID 12507415 DOI: 10.1007/S11910-003-0041-X |
0.408 |
|
| 2003 |
Przedborski S, Goldman JE. Pathogenic role of glial cells in Parkinson's disease Advances in Molecular and Cell Biology. 31: 967-982. DOI: 10.1016/S1569-2558(03)31043-4 |
0.438 |
|
| 2002 |
Wu DC, Tieu K, Cohen O, Choi DK, Vila M, Jackson-Lewis V, Teismann P, Przedborski S. Glial cell response: A pathogenic factor in Parkinson's disease Journal of Neurovirology. 8: 551-558. PMID 12476349 DOI: 10.1080/13550280290100905 |
0.425 |
|
| 2002 |
Drachman DB, Frank K, Dykes-Hoberg M, Teismann P, Almer G, Przedborski S, Rothstein JD. Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS. Annals of Neurology. 52: 771-8. PMID 12447931 DOI: 10.1002/Ana.10374 |
0.402 |
|
| 2002 |
Dauer W, Kholodilov N, Vila M, Trillat AC, Goodchild R, Larsen KE, Staal R, Tieu K, Schmitz Y, Yuan CA, Rocha M, Jackson-Lewis V, Hersch S, Sulzer D, Przedborski S, et al. Resistance of alpha -synuclein null mice to the parkinsonian neurotoxin MPTP. Proceedings of the National Academy of Sciences of the United States of America. 99: 14524-9. PMID 12376616 DOI: 10.1073/Pnas.172514599 |
0.383 |
|
| 2002 |
Guégan C, Vila M, Teismann P, Chen C, Onténiente B, Li M, Friedlander RM, Przedborski S, Teissman P. Instrumental activation of bid by caspase-1 in a transgenic mouse model of ALS. Molecular and Cellular Neurosciences. 20: 553-62. PMID 12213439 DOI: 10.1006/Mcne.2002.1136 |
0.34 |
|
| 2002 |
Zhu S, Stavrovskaya IG, Drozda M, Kim BY, Ona V, Li M, Sarang S, Liu AS, Hartley DM, Wu DC, Gullans S, Ferrante RJ, Przedborski S, Kristal BS, Friedlander RM. Minocycline inhibits cytochrome c release and delays progression of amyotrophic lateral sclerosis in mice. Nature. 417: 74-8. PMID 11986668 DOI: 10.1038/417074A |
0.377 |
|
| 2002 |
Almer G, Teismann P, Stevic Z, Halaschek-Wiener J, Deecke L, Kostic V, Przedborski S. Increased levels of the pro-inflammatory prostaglandin PGE2 in CSF from ALS patients Neurology. 58: 1277-1279. PMID 11971099 DOI: 10.1212/Wnl.58.8.1277 |
0.31 |
|
| 2002 |
Wu DC, Jackson-Lewis V, Vila M, Tieu K, Teismann P, Vadseth C, Choi DK, Ischiropoulos H, Przedborski S. Blockade of microglial activation is neuroprotective in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 1763-71. PMID 11880505 DOI: 10.1523/Jneurosci.22-05-01763.2002 |
0.426 |
|
| 2001 |
Vila M, Wu DC, Przedborski S. Engineered modeling and the secrets of Parkinson's disease Trends in Neurosciences. 24: S49-55. PMID 11881746 DOI: 10.1016/S0166-2236(00)01984-6 |
0.38 |
|
| 2001 |
Feigin A, Fukuda M, Dhawan V, Przedborski S, Jackson-Lewis V, Mentis MJ, Moeller JR, Eidelberg D. Metabolic correlates of levodopa response in Parkinson's disease Neurology. 57: 2083-2088. PMID 11739830 DOI: 10.1212/Wnl.57.11.2083 |
0.328 |
|
| 2001 |
Petersén A, Hansson O, Puschban Z, Sapp E, Romero N, Castilho RF, Sulzer D, Rice M, DiFiglia M, Przedborski S, Brundin P. Mice transgenic for exon 1 of the Huntington's disease gene display reduced striatal sensitivity to neurotoxicity induced by dopamine and 6-hydroxydopamine. The European Journal of Neuroscience. 14: 1425-35. PMID 11722604 DOI: 10.1046/J.0953-816X.2001.01765.X |
0.34 |
|
| 2001 |
Petersén A A, Larsen KE, Behr GG, Romero N, Przedborski S, Brundin P, Sulzer D. Brain-derived neurotrophic factor inhibits apoptosis and dopamine-induced free radical production in striatal neurons but does not prevent cell death. Brain Research Bulletin. 56: 331-5. PMID 11719268 DOI: 10.1016/S0361-9230(01)00580-9 |
0.387 |
|
| 2001 |
Guégan C, Vila M, Rosoklija G, Hays AP, Przedborski S. Recruitment of the mitochondrial-dependent apoptotic pathway in amyotrophic lateral sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 6569-76. PMID 11517246 DOI: 10.1523/Jneurosci.21-17-06569.2001 |
0.392 |
|
| 2001 |
Vila M, Jackson-Lewis V, Guégan C, Chu Wu D, Teismann P, Choi DK, Tieu K, Przedborski S. The role of glial cells in Parkinson's disease Current Opinion in Neurology. 14: 483-489. PMID 11470965 DOI: 10.1097/00019052-200108000-00009 |
0.422 |
|
| 2001 |
Matsuoka Y, Vila M, Lincoln S, McCormack A, Picciano M, LaFrancois J, Yu X, Dickson D, Langston WJ, McGowan E, Farrer M, Hardy J, Duff K, Przedborski S, Di Monte DA. Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter. Neurobiology of Disease. 8: 535-9. PMID 11442360 DOI: 10.1006/Nbdi.2001.0392 |
0.362 |
|
| 2001 |
Petersén A, Larsen KE, Behr GG, Romero N, Przedborski S, Brundin P, Sulzer D. Expanded CAG repeats in exon 1 of the Huntington's disease gene stimulate dopamine-mediated striatal neuron autophagy and degeneration. Human Molecular Genetics. 10: 1243-54. PMID 11406606 DOI: 10.1093/Hmg/10.12.1243 |
0.413 |
|
| 2001 |
Vila M, Jackson-Lewis V, Vukosavic S, Djaldetti R, Liberatore G, Offen D, Korsmeyer SJ, Przedborski S. Bax ablation prevents dopaminergic neurodegeneration in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease Proceedings of the National Academy of Sciences of the United States of America. 98: 2837-2842. PMID 11226327 DOI: 10.1073/Pnas.051633998 |
0.45 |
|
| 2001 |
Almer G, Guégan C, Teismann P, Naini A, Rosoklija G, Hays AP, Chen C, Przedborski S. Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis. Annals of Neurology. 49: 176-85. PMID 11220737 DOI: 10.1002/1531-8249(20010201)49:2<176::Aid-Ana37>3.0.Co;2-X |
0.384 |
|
| 2001 |
Przedborski S, Chen Q, Vila M, Giasson BI, Djaldatti R, Vukosavic S, Souza JM, Jackson-Lewis V, Lee VM, Ischiropoulos H. Oxidative post-translational modifications of alpha-synuclein in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease. Journal of Neurochemistry. 76: 637-40. PMID 11208927 DOI: 10.1046/J.1471-4159.2001.00174.X |
0.352 |
|
| 2001 |
Przedborski S, Vila M. MPTP: A review of its mechanisms of neurotoxicity Clinical Neuroscience Research. 1: 407-418. DOI: 10.1016/S1566-2772(01)00019-6 |
0.411 |
|
| 2000 |
Vukosavic S, Stefanis L, Jackson-Lewis V, Guégan C, Romero N, Chen C, Dubois-Dauphin M, Przedborski S. Delaying caspase activation by Bcl-2: A clue to disease retardation in a transgenic mouse model of amyotrophic lateral sclerosis Journal of Neuroscience. 20: 9119-9125. PMID 11124989 DOI: 10.1523/Jneurosci.20-24-09119.2000 |
0.396 |
|
| 2000 |
Jackson-Lewis V, Vila M, Djaldetti R, Guegan C, Liberatore G, Liu J, O'Malley KL, Burke RE, Przedborski S. Developmental cell death in dopaminergic neurons of the substantia nigra of mice. The Journal of Comparative Neurology. 424: 476-88. PMID 10906714 DOI: 10.1002/1096-9861(20000828)424:3<476::Aid-Cne6>3.0.Co;2-0 |
0.389 |
|
| 2000 |
Przedborski S, Vila M, Jackson-Lewis V, Dawson TM. Reply: a new look at the pathogenesis of Parkinson's disease Trends in Pharmacological Sciences. 21: 165. PMID 10785645 DOI: 10.1016/S0165-6147(00)01470-X |
0.471 |
|
| 2000 |
Li M, Ona VO, Guégan C, Chen M, Jackson-Lewis V, Andrews LJ, Olszewski AJ, Stieg PE, Lee JP, Przedborski S, Friedlander RM. Functional role of caspase-1 and caspase-3 in an ALS transgenic mouse model. Science (New York, N.Y.). 288: 335-9. PMID 10764647 DOI: 10.1126/Science.288.5464.335 |
0.373 |
|
| 2000 |
Vila M, Vukosavic S, Jackson-Lewis V, Neystat M, Jakowec M, Przedborski S. α-synuclein up-regulation in substantia nigra dopaminergic neurons following administration of the parkinsonian toxin MPTP Journal of Neurochemistry. 74: 721-729. PMID 10646524 DOI: 10.1046/J.1471-4159.2000.740721.X |
0.429 |
|
| 1999 |
Vukosavic S, Dubois-Dauphin M, Romero N, Przedborski S. Bax and Bcl-2 interaction in a transgenic mouse model of familial amyotrophic lateral sclerosis Journal of Neurochemistry. 73: 2460-2468. PMID 10582606 DOI: 10.1046/J.1471-4159.1999.0732460.X |
0.364 |
|
| 1999 |
Donovan DM, Miner LL, Perry MP, Revay RS, Sharpe LG, Przedborski S, Kostic V, Philpot RM, Kirstein CL, Rothman RB, Schindler CW, Uhl GR. Cocaine reward and MPTP toxicity: alteration by regional variant dopamine transporter overexpression. Brain Research. Molecular Brain Research. 73: 37-49. PMID 10581396 DOI: 10.1016/S0169-328X(99)00235-1 |
0.319 |
|
| 1999 |
Liberatore GT, Jackson-Lewis V, Vukosavic S, Mandir AS, Vila M, McAuliffe WG, Dawson VL, Dawson TM, Przedborski S. Inducible nitric oxide synthase stimulates dopaminergic neurodegeneration in the MPTP model of Parkinson disease. Nature Medicine. 5: 1403-9. PMID 10581083 DOI: 10.1038/70978 |
0.417 |
|
| 1999 |
Pennathur S, Jackson-Lewis V, Przedborski S, Heinecke JW. Mass spectrometric quantification of 3-nitrotyrosine, ortho-tyrosine, and o,o'-dityrosine in brain tissue of 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine-treated mice, a model of oxidative stress in Parkinson's disease. The Journal of Biological Chemistry. 274: 34621-8. PMID 10574926 DOI: 10.1074/Jbc.274.49.34621 |
0.337 |
|
| 1999 |
Kostic VS, Svetel M, Sternic N, Dragasevic N, Przedborski S. Theophylline increases 'on' time in advanced parkinsonian patients Neurology. 52: 1916. PMID 10371549 DOI: 10.1212/Wnl.52.9.1916 |
0.344 |
|
| 1999 |
Almer G, Vukosavic S, Romero N, Przedborski S. Inducible nitric oxide synthase up-regulation in a transgenic mouse model of familial amyotrophic lateral sclerosis Journal of Neurochemistry. 72: 2415-2425. PMID 10349851 DOI: 10.1046/J.1471-4159.1999.0722415.X |
0.375 |
|
| 1999 |
Mandir AS, Przedborski S, Jackson-Lewis V, Wang ZQ, Simbulan-Rosenthal CM, Smulson ME, Hoffman BE, Guastella DB, Dawson VL, Dawson TM. Poly(ADP-ribose) polymerase activation mediates 1-methyl-4-phenyl-1, 2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. 96: 5774-9. PMID 10318960 DOI: 10.1073/Pnas.96.10.5774 |
0.316 |
|
| 1998 |
Przedborski S, Jackson-Lewis V. Experimental developments in movement disorders: Update on proposed free radical mechanisms Current Opinion in Neurology. 11: 335-339. PMID 9725079 DOI: 10.1097/00019052-199808000-00009 |
0.341 |
|
| 1998 |
Ara J, Przedborski S, Naini AB, Jackson-Lewis V, Trifiletti RR, Horwitz J, Ischiropoulos H. Inactivation of tyrosine hydroxylase by nitration following exposure to peroxynitrite and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). Proceedings of the National Academy of Sciences of the United States of America. 95: 7659-63. PMID 9636206 DOI: 10.1073/Pnas.95.13.7659 |
0.37 |
|
| 1997 |
Takahashi N, Miner LL, Sora I, Ujike H, Revay RS, Kostic V, Jackson-Lewis V, Przedborski S, Uhl GR. VMAT2 knockout mice: heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity. Proceedings of the National Academy of Sciences of the United States of America. 94: 9938-43. PMID 9275230 DOI: 10.1073/Pnas.94.18.9938 |
0.312 |
|
| 1997 |
Kostic V, Jackson-Lewis V, De Bilbao F, Dubois-Dauphin M, Przedborski S. Bcl-2: Prolonging life in a transgenic mouse model of familial amyotrophic lateral sclerosis Science. 277: 559-562. PMID 9228005 DOI: 10.1126/Science.277.5325.559 |
0.407 |
|
| 1997 |
Mena MA, Khan U, Togasaki DM, Sulzer D, Epstein CJ, Przedborski S. Effects of wild-type and mutated copper/zinc superoxide dismutase on neuronal survival and L-DOPA-induced toxicity in postnatal midbrain culture. Journal of Neurochemistry. 69: 21-33. PMID 9202290 DOI: 10.1046/J.1471-4159.1997.69010021.X |
0.342 |
|
| 1997 |
Kostic V, Gurney ME, Deng HX, Siddique T, Epstein CJ, Przedborski S. Midbrain dopaminergic neuronal degeneration in a transgenic mouse model of familial amyotrophic lateral sclerosis. Annals of Neurology. 41: 497-504. PMID 9124807 DOI: 10.1002/Ana.410410413 |
0.397 |
|
| 1996 |
Przedborski S, Donaldson D, Jakowec M, Kish SJ, Guttman M, Rosoklija G, Hays AP. Brain superoxide dismutase, catalase, and glutathione peroxidase activities in amyotrophic lateral sclerosis. Annals of Neurology. 39: 158-65. PMID 8967746 DOI: 10.1002/Ana.410390204 |
0.326 |
|
| 1996 |
Przedborski S, Dhawan V, Donaldson DM, Murphy PL, McKenna-Yasek D, Mandel FS, Brown RH, Eidelberg D. Nigrostriatal dopaminergic function in familial amyotrophic lateral sclerosis patients with and without copper/zinc superoxide dismutase mutations. Neurology. 47: 1546-51. PMID 8960743 DOI: 10.1212/Wnl.47.6.1546 |
0.348 |
|
| 1996 |
Przedborski S, Khan U, Kostic V, Carlson E, Epstein CJ, Sulzer D. Increased superoxide dismutase activity improves survival of cultured postnatal midbrain neurons. Journal of Neurochemistry. 67: 1383-92. PMID 8858919 DOI: 10.1046/J.1471-4159.1996.67041383.X |
0.319 |
|
| 1996 |
Przedborski S, Donaldson DM, Murphy PL, Hirsch O, Lange D, Naini AB, McKenna-Yasek D, Brown RH. Blood superoxide dismutase, catalase and glutathione peroxidase activities in familial and sporadic amyotrophic lateral sclerosis. Neurodegeneration : a Journal For Neurodegenerative Disorders, Neuroprotection, and Neuroregeneration. 5: 57-64. PMID 8731383 DOI: 10.1006/Neur.1996.0008 |
0.327 |
|
| 1996 |
Przedborski S, Jackson-Lewis V, Yokoyama R, Shibata T, Dawson VL, Dawson TM. Role of neuronal nitric oxide in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurotoxicity. Proceedings of the National Academy of Sciences of the United States of America. 93: 4565-71. PMID 8643444 DOI: 10.1073/Pnas.93.10.4565 |
0.42 |
|
| 1995 |
Levivier M, Przedborski S, Bencsics C, Kang UJ. Intrastriatal implantation of fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevents degeneration of dopaminergic neurons in a rat model of Parkinson's disease Journal of Neuroscience. 15: 7810-7820. PMID 8613721 |
0.306 |
|
| 1995 |
Jackson-Lewis V, Jakowec M, Burke RE, Przedborski S. Time course and morphology of dopaminergic neuronal death caused by the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Neurodegeneration : a Journal For Neurodegenerative Disorders, Neuroprotection, and Neuroregeneration. 4: 257-69. PMID 8581558 DOI: 10.1016/1055-8330(95)90015-2 |
0.385 |
|
| 1995 |
Przedborski S, Jackson-Lewis V, Fahn S. Antiparkinsonian therapies and brain mitochondrial complex I activity. Movement Disorders : Official Journal of the Movement Disorder Society. 10: 312-7. PMID 7651449 DOI: 10.1002/Mds.870100314 |
0.341 |
|
| 1994 |
Eidelberg D, Moeller JR, Dhawan V, Spetsieris P, Takikawa S, Ishikawa T, Chaly T, Robeson W, Margouleff D, Przedborski S. The metabolic topography of parkinsonism. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 14: 783-801. PMID 8063874 DOI: 10.1038/Jcbfm.1994.99 |
0.313 |
|
| 1994 |
Muthane U, Ramsay KA, Jiang H, Jackson-Lewis V, Donaldson D, Fernando S, Ferreira M, Przedborski S. Differences in nigral neuron number and sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in C57/bl and CD-1 mice. Experimental Neurology. 126: 195-204. PMID 7925820 DOI: 10.1006/Exnr.1994.1058 |
0.342 |
|
| 1993 |
Przedborski S, Jackson-Lewis V, Muthane U, Jiang H, Ferreira M, Naini AB, Fahn S. Chronic levodopa administration alters cerebral mitochondrial respiratory chain activity. Annals of Neurology. 34: 715-23. PMID 8239566 DOI: 10.1002/Ana.410340515 |
0.363 |
|
| 1992 |
Giladi N, McMahon D, Przedborski S, Flaster E, Guillory S, Kostic V, Fahn S. Motor blocks in Parkinson's disease. Neurology. 42: 333-9. PMID 1736161 DOI: 10.1212/Wnl.42.2.333 |
0.368 |
|
| 1992 |
Przedborski S, Kostic V, Jackson-Lewis V, Naini AB, Simonetti S, Fahn S, Carlson E, Epstein CJ, Cadet JL. Transgenic mice with increased Cu/Zn-superoxide dismutase activity are resistant to N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 12: 1658-67. PMID 1578260 DOI: 10.1523/Jneurosci.12-05-01658.1992 |
0.393 |
|
| 1991 |
Kostic V, Przedborski S, Flaster E, Sternic N. Early development of levodopa-induced dyskinesias and response fluctuations in young-onset Parkinson's disease. Neurology. 41: 202-202. PMID 1992362 DOI: 10.1212/Wnl.41.2_Part_1.202 |
0.325 |
|
| 1991 |
Przedborski S, Levivier M, Kostic V, Jackson-Lewis V, Dollison A, Gash DM, Fahn S, Cadet JL. Sham transplantation protects against 6-hydroxydopamine-induced dopaminergic toxicity in rats: behavioral and morphological evidence. Brain Research. 550: 231-8. PMID 1832076 DOI: 10.1016/0006-8993(91)91323-S |
0.331 |
|
| 1991 |
Cadet JL, Kujirai K, Przedborski S. Bilateral modulation of [3H]neurotensin binding by unilateral intrastriatal 6-hydroxydopamine injections: evidence from a receptor autoradiographic study. Brain Research. 564: 37-44. PMID 1663814 DOI: 10.1016/0006-8993(91)91349-6 |
0.303 |
|
| 1990 |
Cadet JL, Przedborski S, Kostic V, Jackson-Lewis V, Carlson E, Epstein CJ. Quantitative autoradiographic distribution of [3H]mazindol-labeled dopamine uptake sites in the brains of superoxide dismutase transgenic mice. Brain Research Bulletin. 25: 187-92. PMID 2119856 DOI: 10.1016/0361-9230(90)90274-4 |
0.346 |
|
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