Sebastian Brandner, MD, FRCPath - Publications

Affiliations: 
Neuropathology University College London, London, United Kingdom 
Area:
Peripheral Neuropathies
Website:
http://www.cnmd.ac.uk/researchgroups/sbrandner

142 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Asante EA, Linehan JM, Tomlinson A, Jakubcova T, Hamdan S, Grimshaw A, Smidak M, Jeelani A, Nihat A, Mead S, Brandner S, Wadsworth JDF, Collinge J. Spontaneous generation of prions and transmissible PrP amyloid in a humanised transgenic mouse model of A117V GSS. Plos Biology. 18: e3000725. PMID 32516343 DOI: 10.1371/Journal.Pbio.3000725  0.397
2020 Schottlaender LV, Abeti R, Jaunmuktane Z, Macmillan C, Chelban V, O'Callaghan B, McKinley J, Maroofian R, Efthymiou S, Athanasiou-Fragkouli A, Forbes R, Soutar MPM, Livingston JH, Kalmar B, Swayne O, ... ... Brandner S, et al. Bi-allelic JAM2 Variants Lead to Early-Onset Recessive Primary Familial Brain Calcification. American Journal of Human Genetics. 106: 412-421. PMID 32142645 DOI: 10.1016/J.Ajhg.2020.02.007  0.348
2020 Ricci B, Millner TO, Pomella N, Zhang X, Guglielmi L, Badodi S, Ceric D, Gemma C, Cognolato E, Zhang Y, Brandner S, Barnes MR, Marino S. Polycomb-mediated repression of EphrinA5 promotes growth and invasion of glioblastoma. Oncogene. PMID 31988455 DOI: 10.1038/S41388-020-1161-3  0.303
2020 Jaunmuktane Z, Brandner S. Invited Review: The role of prion-like mechanisms in neurodegenerative diseases. Neuropathology and Applied Neurobiology. PMID 31868945 DOI: 10.1111/Nan.12592  0.329
2019 Bödör C, Alpár D, Marosvári D, Galik B, Rajnai H, Bátai B, Nagy Á, Kajtár B, Burján A, Deák B, Schneider T, Alizadeh H, Matolcsy A, Brandner S, Storhoff J, et al. Molecular Subtypes and Genomic Profile of Primary Central Nervous System Lymphoma. Journal of Neuropathology and Experimental Neurology. PMID 31886867 DOI: 10.1093/Jnen/Nlz125  0.328
2019 Katrak SM, Pauranik A, Desai SB, Mead S, Beck J, Brandner S, Collinge J. Familial Creutzfeldt-Jakob Disease in an Indian Kindred. Annals of Indian Academy of Neurology. 22: 458-461. PMID 31736569 DOI: 10.4103/Aian.Aian_214_19  0.356
2019 Sievers P, Appay R, Schrimpf D, Stichel D, Reuss DE, Wefers AK, Reinhardt A, Coras R, Ruf VC, Schmid S, de Stricker K, Boldt HB, Kristensen BW, Petersen JK, Ulhøi BP, ... ... Brandner S, et al. Rosette-forming glioneuronal tumors share a distinct DNA methylation profile and mutations in FGFR1, with recurrent co-mutation of PIK3CA and NF1. Acta Neuropathologica. PMID 31250151 DOI: 10.1007/S00401-019-02038-4  0.324
2019 Rudge P, Jaunmuktane Z, Hyare H, Ellis M, Koltzenburg M, Collinge J, Brandner S, Mead S. Early neurophysiological biomarkers and spinal cord pathology in inherited prion disease. Brain : a Journal of Neurology. PMID 30698738 DOI: 10.1093/Brain/Awy358  0.335
2019 Brandner S, Jaunmuktane Z. IDH mutant astrocytoma: biomarkers for prognostic stratification and the next frontiers Neuropathology and Applied Neurobiology. 45: 91-94. PMID 30326147 DOI: 10.1111/Nan.12521  0.339
2019 Jaunmuktane Z, Brandner S. Transmissible human proteopathies: an expanding field Diagnostic Histopathology. 25: 16-22. DOI: 10.1016/J.Mpdhp.2018.11.002  0.312
2018 Purro SA, Farrow MA, Linehan J, Nazari T, Thomas DX, Chen Z, Mengel D, Saito T, Saido T, Rudge P, Brandner S, Walsh DM, Collinge J. Transmission of amyloid-β protein pathology from cadaveric pituitary growth hormone. Nature. PMID 30546139 DOI: 10.1038/S41586-018-0790-Y  0.316
2018 Stichel D, Ebrahimi A, Reuss D, Schrimpf D, Ono T, Shirahata M, Reifenberger G, Weller M, Hänggi D, Wick W, Herold-Mende C, Westphal M, Brandner S, Pfister SM, Capper D, et al. Distribution of EGFR amplification, combined chromosome 7 gain and chromosome 10 loss, and TERT promoter mutation in brain tumors and their potential for the reclassification of IDHwt astrocytoma to glioblastoma. Acta Neuropathologica. PMID 30187121 DOI: 10.1007/S00401-018-1905-0  0.3
2018 Massaro G, Mattar CNZ, Wong AMS, Sirka E, Buckley SMK, Herbert BR, Karlsson S, Perocheau DP, Burke D, Heales S, Richard-Londt A, Brandner S, Huebecker M, Priestman DA, Platt FM, et al. Fetal gene therapy for neurodegenerative disease of infants. Nature Medicine. PMID 30013199 DOI: 10.1038/S41591-018-0106-7  0.362
2018 Deng MY, Sill M, Chiang J, Schittenhelm J, Ebinger M, Schuhmann MU, Monoranu CM, Milde T, Wittmann A, Hartmann C, Sommer C, Paulus W, Gärtner J, Brück W, Rüdiger T, ... ... Brandner S, et al. Molecularly defined diffuse leptomeningeal glioneuronal tumor (DLGNT) comprises two subgroups with distinct clinical and genetic features. Acta Neuropathologica. PMID 29766299 DOI: 10.1007/S00401-018-1865-4  0.312
2018 Li N, Zhang Y, Sidlauskas K, Ellis M, Evans I, Frankel P, Lau J, El-Hassan T, Guglielmi L, Broni J, Richard-Loendt A, Brandner S. Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades. Oncogene. PMID 29720725 DOI: 10.1038/S41388-018-0277-1  0.308
2018 Jaunmuktane Z, Quaegebeur A, Taipa R, Viana-Baptista M, Barbosa R, Koriath C, Sciot R, Mead S, Brandner S. Evidence of amyloid-β cerebral amyloid angiopathy transmission through neurosurgery Acta Neuropathologica. 135: 671-679. PMID 29450646 DOI: 10.1007/S00401-018-1822-2  0.324
2018 Joiner S, Asante EA, Linehan JM, Brock L, Brandner S, Bellworthy SJ, Simmons MM, Hope J, Collinge J, Wadsworth JDF. Experimental sheep BSE prions generate the vCJD phenotype when serially passaged in transgenic mice expressing human prion protein. Journal of the Neurological Sciences. 386: 4-11. PMID 29406965 DOI: 10.1016/J.Jns.2017.12.038  0.364
2017 Pathania M, De Jay N, Maestro N, Harutyunyan AS, Nitarska J, Pahlavan P, Henderson S, Mikael LG, Richard-Londt A, Zhang Y, Costa JR, Hébert S, Khazaei S, Ibrahim NS, Herrero J, ... ... Brandner S, et al. H3.3(K27M) Cooperates with Trp53 Loss and PDGFRA Gain in Mouse Embryonic Neural Progenitor Cells to Induce Invasive High-Grade Gliomas. Cancer Cell. PMID 29107533 DOI: 10.1016/J.Ccell.2017.09.014  0.307
2017 Tarpey PS, Behjati S, Young MD, Martincorena I, Alexandrov LB, Farndon SJ, Guzzo C, Hardy C, Latimer C, Butler AP, Teague JW, Shlien A, Futreal PA, Shah S, Bashashati A, ... ... Brandner S, et al. The driver landscape of sporadic chordoma. Nature Communications. 8: 890. PMID 29026114 DOI: 10.1038/S41467-017-01026-0  0.306
2017 Wadsworth JDF, Adamson G, Joiner S, Brock L, Powell C, Linehan JM, Beck JA, Brandner S, Mead S, Collinge J. Methods for Molecular Diagnosis of Human Prion Disease. Methods in Molecular Biology (Clifton, N.J.). 1658: 311-346. PMID 28861799 DOI: 10.1007/978-1-4939-7244-9_22  0.369
2017 Kulshrestha R, Burton-Jones S, Antoniadi T, Rogers M, Jaunmuktane Z, Brandner S, Kiely N, Manuel R, Willis T. Deletion of P2 promoter of GJB1 gene a cause of Charcot-Marie-Tooth disease. Neuromuscular Disorders : Nmd. PMID 28601552 DOI: 10.1016/J.Nmd.2017.05.001  0.324
2017 Haston S, Pozzi S, Carreno G, Manshaei S, Panousopoulos L, Gonzalez-Meljem JM, Apps JR, Virasami A, Thavaraj S, Gutteridge A, Forshew T, Marais R, Brandner S, Jacques TS, Andoniadou CL, et al. MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma. Development. 144: 2141-2152. PMID 28506993 DOI: 10.1242/Dev.150490  0.302
2017 Horga A, Laurà M, Jaunmuktane Z, Jerath NU, Gonzalez MA, Polke JM, Poh R, Blake JC, Liu YT, Wiethoff S, Bettencourt C, Lunn MP, Manji H, Hanna MG, Houlden H, ... Brandner S, et al. Genetic and clinical characteristics of NEFL-related Charcot-Marie-Tooth disease. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 28501821 DOI: 10.1136/Jnnp-2016-315077  0.321
2017 Cummings DM, Benway TA, Ho H, Tedoldi A, Fernandes Freitas MM, Shahab L, Murray CE, Richard-Loendt A, Brandner S, Lashley T, Salih DA, Edwards FA. Neuronal and Peripheral Pentraxins Modify Glutamate Release and may Interact in Blood-Brain Barrier Failure. Cerebral Cortex (New York, N.Y. : 1991). 1-12. PMID 28334103 DOI: 10.1093/Cercor/Bhx046  0.313
2017 Mok T, Jaunmuktane Z, Joiner S, Campbell T, Morgan C, Wakerley B, Golestani F, Rudge P, Mead S, Jäger HR, Wadsworth JD, Brandner S, Collinge J. Variant Creutzfeldt-Jakob Disease in a Patient with Heterozygosity at PRNP Codon 129. The New England Journal of Medicine. 376: 292-294. PMID 28099827 DOI: 10.1056/Nejmc1610003  0.344
2017 Brandner S, Jaunmuktane Z. Prion disease: experimental models and reality. Acta Neuropathologica. 133: 197-222. PMID 28084518 DOI: 10.1007/S00401-017-1670-5  0.332
2016 Kara E, Tucci A, Manzoni C, Lynch DS, Elpidorou M, Bettencourt C, Chelban V, Manole A, Hamed SA, Haridy NA, Federoff M, Preza E, Hughes D, Pittman A, Jaunmuktane Z, ... Brandner S, et al. Genetic and phenotypic characterization of complex hereditary spastic paraplegia. Brain : a Journal of Neurology. PMID 27217339 DOI: 10.1093/Brain/Aww111  0.353
2016 Mead S, Burnell M, Lowe J, Thompson A, Lukic A, Porter MC, Carswell C, Kaski D, Kenny J, Mok TH, Bjurstrom N, Franko E, Gorham M, Druyeh R, Wadsworth JD, ... ... Brandner S, et al. Clinical Trial Simulations Based on Genetic Stratification and the Natural History of a Functional Outcome Measure in Creutzfeldt-Jakob Disease. Jama Neurology. PMID 26902324 DOI: 10.1001/Jamaneurol.2015.4885  0.33
2016 Benedykcinska A, Ferreira A, Lau J, Broni J, Richard-Loendt A, Henriquez NV, Brandner S. Generation of brain tumours in mice by Cre-mediated recombination of neural progenitors in situ with the tamoxifen metabolite endoxifen Dmm Disease Models and Mechanisms. 9: 211-220. DOI: 10.1242/Dmm.022715  0.34
2015 McKinnon C, Goold R, Andre R, Devoy A, Ortega Z, Moonga J, Linehan JM, Brandner S, Lucas JJ, Collinge J, Tabrizi SJ. Prion-mediated neurodegeneration is associated with early impairment of the ubiquitin-proteasome system. Acta Neuropathologica. PMID 26646779 DOI: 10.1007/S00401-015-1508-Y  0.358
2015 Schmidt C, Fizet J, Properzi F, Batchelor M, Sandberg MK, Edgeworth JA, Afran L, Ho S, Badhan A, Klier S, Linehan JM, Brandner S, Hosszu LL, Tattum MH, Jat P, et al. A systematic investigation of production of synthetic prions from recombinant prion protein. Open Biology. 5. PMID 26631378 DOI: 10.1098/Rsob.150165  0.31
2015 Eisenmenger L, Porter MC, Carswell CJ, Thompson A, Mead S, Rudge P, Collinge J, Brandner S, Jäger HR, Hyare H. Evolution of Diffusion-Weighted Magnetic Resonance Imaging Signal Abnormality in Sporadic Creutzfeldt-Jakob Disease, With Histopathological Correlation. Jama Neurology. 1-9. PMID 26569479 DOI: 10.1001/Jamaneurol.2015.3159  0.316
2015 Jaunmuktane Z, Mead S, Ellis M, Wadsworth JD, Nicoll AJ, Kenny J, Launchbury F, Linehan J, Richard-Loendt A, Walker AS, Rudge P, Collinge J, Brandner S. Evidence for human transmission of amyloid-β pathology and cerebral amyloid angiopathy. Nature. 525: 247-50. PMID 26354483 DOI: 10.1038/Nature15369  0.346
2015 Rudge P, Jaunmuktane Z, Adlard P, Bjurstrom N, Caine D, Lowe J, Norsworthy P, Hummerich H, Druyeh R, Wadsworth JD, Brandner S, Hyare H, Mead S, Collinge J. Iatrogenic CJD due to pituitary-derived growth hormone with genetically determined incubation times of up to 40 years. Brain : a Journal of Neurology. 138: 3386-99. PMID 26268531 DOI: 10.1093/Brain/Awv235  0.365
2015 Saunus JM, Quinn MC, Patch AM, Pearson JV, Bailey PJ, Nones K, McCart Reed AE, Miller D, Wilson PJ, Al-Ejeh F, Mariasegaram M, Lau Q, Withers T, Jeffree RL, Reid LE, ... ... Brandner S, et al. Integrated genomic and transcriptomic analysis of human brain metastases identifies alterations of potential clinical significance. The Journal of Pathology. PMID 26172396 DOI: 10.1002/Path.4583  0.31
2015 Asante EA, Grimshaw A, Smidak M, Jakubcova T, Tomlinson A, Jeelani A, Hamdan S, Powell C, Joiner S, Linehan JM, Brandner S, Wadsworth JD, Collinge J. Transmission Properties of Human PrP 102L Prions Challenge the Relevance of Mouse Models of GSS. Plos Pathogens. 11: e1004953. PMID 26135918 DOI: 10.1371/Journal.Ppat.1004953  0.354
2015 Asante EA, Smidak M, Grimshaw A, Houghton R, Tomlinson A, Jeelani A, Jakubcova T, Hamdan S, Richard-Londt A, Linehan JM, Brandner S, Alpers M, Whitfield J, Mead S, Wadsworth JD, et al. A naturally occurring variant of the human prion protein completely prevents prion disease. Nature. 522: 478-81. PMID 26061765 DOI: 10.1038/Nature14510  0.372
2015 Lynch DS, Jaunmuktane Z, Sheerin UM, Phadke R, Brandner S, Milonas I, Dean A, Bajaj N, McNicholas N, Costello D, Cronin S, McGuigan C, Rossor M, Fox N, Murphy E, et al. Hereditary leukoencephalopathy with axonal spheroids: a spectrum of phenotypes from CNS vasculitis to parkinsonism in an adult onset leukodystrophy series. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 25935893 DOI: 10.1136/Jnnp-2015-310788  0.322
2015 Hyare H, So PW, Brandner S, Collinge J, Parkes HG. MRI detection of prion protein plaques in variant Creutzfeldt-Jakob disease. Neurology. 84: 1498-9. PMID 25846996 DOI: 10.1212/Wnl.0000000000000304  0.331
2015 Carr AS, Pelayo-Negro AL, Jaunmuktane Z, Scalco RS, Hutt D, Evans MR, Heally E, Brandner S, Holton J, Blake J, Whelan CJ, Wechalekar AD, Gillmore JD, Hawkins PN, Reilly MM. Transthyretin V122I amyloidosis with clinical and histological evidence of amyloid neuropathy and myopathy. Neuromuscular Disorders : Nmd. 25: 511-5. PMID 25819286 DOI: 10.1016/J.Nmd.2015.02.001  0.306
2015 Joyce PI, Mcgoldrick P, Saccon RA, Weber W, Fratta P, West SJ, Zhu N, Carter S, Phatak V, Stewart M, Simon M, Kumar S, Heise I, Bros-Facer V, Dick J, ... ... Brandner S, et al. A novel SOD1-ALS mutation separates central and peripheral effects of mutant SOD1 toxicity. Human Molecular Genetics. 24: 1883-97. PMID 25468678 DOI: 10.1093/Hmg/Ddu605  0.353
2015 Mirabile I, Jat PS, Brandner S, Collinge J. Identification of clinical target areas in the brainstem of prion-infected mice. Neuropathology and Applied Neurobiology. 41: 613-30. PMID 25311251 DOI: 10.1111/Nan.12189  0.301
2015 Li N, Sidlauskas K, Brandner S. Po26Microrna-449A Is Important For Impeding The Growth And Invasion Of Tumour Initiating Cells In Experimental Brain Tumour Models Neuro-Oncology. 17. DOI: 10.1093/Neuonc/Nov284.22  0.34
2014 Cottenie E, Kochanski A, Jordanova A, Bansagi B, Zimon M, Horga A, Jaunmuktane Z, Saveri P, Rasic VM, Baets J, Bartsakoulia M, Ploski R, Teterycz P, Nikolic M, Quinlivan R, ... ... Brandner S, et al. Truncating and missense mutations in IGHMBP2 cause Charcot-Marie Tooth disease type 2. American Journal of Human Genetics. 95: 590-601. PMID 25439726 DOI: 10.1016/J.Ajhg.2014.10.002  0.337
2014 Liu YT, Laurá M, Hersheson J, Horga A, Jaunmuktane Z, Brandner S, Pittman A, Hughes D, Polke JM, Sweeney MG, Proukakis C, Janssen JC, Auer-Grumbach M, Zuchner S, Shields KG, et al. Extended phenotypic spectrum of KIF5A mutations: From spastic paraplegia to axonal neuropathy. Neurology. 83: 612-9. PMID 25008398 DOI: 10.1212/Wnl.0000000000000691  0.319
2014 Grizenkova J, Akhtar S, Brandner S, Collinge J, Lloyd SE. Microglial Cx3cr1 knockout reduces prion disease incubation time in mice. Bmc Neuroscience. 15: 44. PMID 24655482 DOI: 10.1186/1471-2202-15-44  0.357
2014 Ricketts T, McGoldrick P, Fratta P, de Oliveira HM, Kent R, Phatak V, Brandner S, Blanco G, Greensmith L, Acevedo-Arozena A, Fisher EM. A nonsense mutation in mouse Tardbp affects TDP43 alternative splicing activity and causes limb-clasping and body tone defects. Plos One. 9: e85962. PMID 24465814 DOI: 10.1371/Journal.Pone.0085962  0.355
2014 Mead S, Wadsworth JD, Porter MC, Linehan JM, Pietkiewicz W, Jackson GS, Brandner S, Collinge J. Variant Creutzfeldt-Jakob disease with extremely low lymphoreticular deposition of prion protein. Jama Neurology. 71: 340-3. PMID 24445428 DOI: 10.1001/Jamaneurol.2013.5378  0.353
2014 Foley AR, Menezes MP, Pandraud A, Gonzalez MA, Al-Odaib A, Abrams AJ, Sugano K, Yonezawa A, Manzur AY, Burns J, Hughes I, McCullagh BG, Jungbluth H, Lim MJ, Lin JP, ... ... Brandner S, et al. Treatable childhood neuronopathy caused by mutations in riboflavin transporter RFVT2. Brain : a Journal of Neurology. 137: 44-56. PMID 24253200 DOI: 10.1093/Brain/Awt315  0.341
2014 Tucci A, Liu YT, Preza E, Pitceathly RD, Chalasani A, Plagnol V, Land JM, Trabzuni D, Ryten M, Jaunmuktane Z, Reilly MM, Brandner S, Hargreaves I, Hardy J, et al. Novel C12orf65 mutations in patients with axonal neuropathy and optic atrophy. Journal of Neurology, Neurosurgery, and Psychiatry. 85: 486-92. PMID 24198383 DOI: 10.1136/Jnnp-2013-306387  0.335
2014 Sidlauskas K, Li N, Lau J, Ferreira A, Brandner S. O03Idh1 Mutations In Neural Stem Cells Promote Migration And Invasion And Act Synergistically With P53 And Pten Loss In Murine Tumour Cells Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou250.3  0.341
2014 Brandner S, Benedykcinska A, Li N, Henriquez N. Novel Approach To Model Brain Tumours By Inducing Locally Restricted And Stem Cell Selective Gene Targeting. Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou206.25  0.324
2014 Brandner S, Henriquez N, Benedykcinska A, Li N, Lau J, Sidlauskas K. O4.10Cns Stem Cell Specific Tumourigenesis Reveals Lineage Relationship Between Experimental And Human Gliomas And A Dominance Of Glial Signatures During Tumour Propagation In Vitro Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou174.31  0.355
2013 Reiniger L, Mirabile I, Lukic A, Wadsworth JD, Linehan JM, Groves M, Lowe J, Druyeh R, Rudge P, Collinge J, Mead S, Brandner S. Filamentous white matter prion protein deposition is a distinctive feature of multiple inherited prion diseases. Acta Neuropathologica Communications. 1: 8. PMID 24252267 DOI: 10.1186/2051-5960-1-8  0.366
2013 Mead S, Gandhi S, Beck J, Caine D, Gajulapalli D, Gallujipali D, Carswell C, Hyare H, Joiner S, Ayling H, Lashley T, Linehan JM, Al-Doujaily H, Sharps B, Revesz T, ... ... Brandner S, et al. A novel prion disease associated with diarrhea and autonomic neuropathy. The New England Journal of Medicine. 369: 1904-14. PMID 24224623 DOI: 10.1056/Nejmoa1214747  0.406
2013 Wadsworth JD, Joiner S, Linehan JM, Balkema-Buschmann A, Spiropoulos J, Simmons MM, Griffiths PC, Groschup MH, Hope J, Brandner S, Asante EA, Collinge J. Atypical scrapie prions from sheep and lack of disease in transgenic mice overexpressing human prion protein. Emerging Infectious Diseases. 19: 1731-9. PMID 24188521 DOI: 10.3201/Eid1911.121341  0.355
2013 Asante EA, Linehan JM, Smidak M, Tomlinson A, Grimshaw A, Jeelani A, Jakubcova T, Hamdan S, Powell C, Brandner S, Wadsworth JD, Collinge J. Inherited prion disease A117V is not simply a proteinopathy but produces prions transmissible to transgenic mice expressing homologous prion protein. Plos Pathogens. 9: e1003643. PMID 24086135 DOI: 10.1371/Journal.Ppat.1003643  0.402
2013 Henriquez NV, Forshew T, Tatevossian R, Ellis M, Richard-Loendt A, Rogers H, Jacques TS, Reitboeck PG, Pearce K, Sheer D, Grundy RG, Brandner S. Comparative expression analysis reveals lineage relationships between human and murine gliomas and a dominance of glial signatures during tumor propagation in vitro. Cancer Research. 73: 5834-44. PMID 23887970 DOI: 10.1158/0008-5472.Can-13-1299  0.309
2013 Cottenie E, Menezes MP, Rossor AM, Morrow JM, Yousry TA, Dick DJ, Anderson JR, Jaunmuktane Z, Brandner S, Blake JC, Houlden H, Reilly MM. Rapidly progressive asymmetrical weakness in Charcot-Marie-Tooth disease type 4J resembles chronic inflammatory demyelinating polyneuropathy. Neuromuscular Disorders : Nmd. 23: 399-403. PMID 23489662 DOI: 10.1016/J.Nmd.2013.01.010  0.34
2013 Akhtar S, Grizenkova J, Wenborn A, Hummerich H, Fernandez de Marco M, Brandner S, Collinge J, Lloyd SE. Sod1 deficiency reduces incubation time in mouse models of prion disease. Plos One. 8: e54454. PMID 23349894 DOI: 10.1371/Journal.Pone.0054454  0.336
2013 Acquati S, Greco A, Licastro D, Bhagat H, Ceric D, Rossini Z, Grieve J, Shaked-Rabi M, Henriquez NV, Brandner S, Stupka E, Marino S. Epigenetic regulation of survivin by Bmi1 is cell type specific during corticogenesis and in gliomas. Stem Cells (Dayton, Ohio). 31: 190-202. PMID 23132836 DOI: 10.1002/Stem.1274  0.308
2012 Grizenkova J, Akhtar S, Hummerich H, Tomlinson A, Asante EA, Wenborn A, Fizet J, Poulter M, Wiseman FK, Fisher EM, Tybulewicz VL, Brandner S, Collinge J, Lloyd SE. Overexpression of the Hspa13 (Stch) gene reduces prion disease incubation time in mice. Proceedings of the National Academy of Sciences of the United States of America. 109: 13722-7. PMID 22869728 DOI: 10.1073/Pnas.1208917109  0.358
2012 Ghazi-Noori S, Froud KE, Mizielinska S, Powell C, Smidak M, Fernandez de Marco M, O'Malley C, Farmer M, Parkinson N, Fisher EM, Asante EA, Brandner S, Collinge J, Isaacs AM. Progressive neuronal inclusion formation and axonal degeneration in CHMP2B mutant transgenic mice. Brain : a Journal of Neurology. 135: 819-32. PMID 22366797 DOI: 10.1093/Brain/Aws006  0.362
2012 Castro-Seoane R, Hummerich H, Sweeting T, Tattum MH, Linehan JM, Fernandez de Marco M, Brandner S, Collinge J, Klöhn PC. Plasmacytoid dendritic cells sequester high prion titres at early stages of prion infection. Plos Pathogens. 8: e1002538. PMID 22359509 DOI: 10.1371/Journal.Ppat.1002538  0.31
2012 Davidson G, Murphy S, Polke J, Laura M, Salih M, Muntoni F, Blake J, Brandner S, Davies N, Horvath R, Price S, Donaghy M, Roberts M, Foulds N, Ramdharry G, et al. Frequency of mutations in the genes associated with hereditary sensory and autonomic neuropathy in a UK cohort. Journal of Neurology. 259: 1673-85. PMID 22302274 DOI: 10.1007/S00415-011-6397-Y  0.316
2012 Klöhn PC, Farmer M, Linehan JM, O'Malley C, Fernandez de Marco M, Taylor W, Farrow M, Khalili-Shirazi A, Brandner S, Collinge J. PrP antibodies do not trigger mouse hippocampal neuron apoptosis. Science (New York, N.Y.). 335: 52. PMID 22223800 DOI: 10.1126/Science.1215579  0.32
2012 Hyare H, Ramlackhansingh A, Gelosa G, Edison P, Rudge P, Brandner S, Brooks DJ, Collinge J, Mead S. 11C-PiB PET does not detect PrP-amyloid in prion disease patients including variant Creutzfeldt-Jakob disease. Journal of Neurology, Neurosurgery, and Psychiatry. 83: 340-1. PMID 21478204 DOI: 10.1136/Jnnp.2010.233692  0.322
2012 Murphy SM, Davidson GL, Brandner S, Houlden H, Reilly MM. Mutation in FAM134B causing severe hereditary sensory neuropathy. Journal of Neurology, Neurosurgery, and Psychiatry. 83: 119-20. PMID 21115472 DOI: 10.1136/Jnnp.2010.228965  0.324
2011 Akhtar S, Wenborn A, Brandner S, Collinge J, Lloyd SE. Sex effects in mouse prion disease incubation time. Plos One. 6: e28741. PMID 22174884 DOI: 10.1371/Journal.Pone.0028741  0.33
2011 Kaski DN, Pennington C, Beck J, Poulter M, Uphill J, Bishop MT, Linehan JM, O'Malley C, Wadsworth JD, Joiner S, Knight RS, Ironside JW, Brandner S, Collinge J, Mead S. Inherited prion disease with 4-octapeptide repeat insertion: disease requires the interaction of multiple genetic risk factors. Brain : a Journal of Neurology. 134: 1829-38. PMID 21616973 DOI: 10.1093/Brain/Awr079  0.354
2011 Murphy SM, Polke J, Manji H, Blake J, Reiniger L, Sweeney M, Houlden H, Brandner S, Reilly MM. A novel mutation in the nerve-specific 5'UTR of the GJB1 gene causes X-linked Charcot-Marie-Tooth disease. Journal of the Peripheral Nervous System : Jpns. 16: 65-70. PMID 21504505 DOI: 10.1111/J.1529-8027.2011.00321.X  0.31
2011 Cleary JO, Wiseman FK, Norris FC, Price AN, Choy M, Tybulewicz VL, Ordidge RJ, Brandner S, Fisher EM, Lythgoe MF. Structural correlates of active-staining following magnetic resonance microscopy in the mouse brain. Neuroimage. 56: 974-83. PMID 21310249 DOI: 10.1016/J.Neuroimage.2011.01.082  0.312
2011 Wadsworth JD, Dalmau-Mena I, Joiner S, Linehan JM, O'Malley C, Powell C, Brandner S, Asante EA, Ironside JW, Hilton DA, Collinge J. Effect of fixation on brain and lymphoreticular vCJD prions and bioassay of key positive specimens from a retrospective vCJD prevalence study. The Journal of Pathology. 223: 511-8. PMID 21294124 DOI: 10.1002/Path.2821  0.325
2011 Russo M, Laurá M, Polke JM, Davis MB, Blake J, Brandner S, Hughes RA, Houlden H, Bennett DL, Lunn MP, Reilly MM. Variable phenotypes are associated with PMP22 missense mutations. Neuromuscular Disorders : Nmd. 21: 106-14. PMID 21194947 DOI: 10.1016/J.Nmd.2010.11.011  0.323
2011 Brandner S. Diversity of prion diseases: (no) strains attached? Acta Neuropathologica. 121: 1-4. PMID 21080180 DOI: 10.1007/S00401-010-0775-X  0.381
2011 Reiniger L, Lukic A, Linehan J, Rudge P, Collinge J, Mead S, Brandner S. Tau, prions and Aβ: the triad of neurodegeneration. Acta Neuropathologica. 121: 5-20. PMID 20473510 DOI: 10.1007/S00401-010-0691-0  0.326
2010 de Marco MF, Linehan J, Gill ON, Clewley JP, Brandner S. Large-scale immunohistochemical examination for lymphoreticular prion protein in tonsil specimens collected in Britain. The Journal of Pathology. 222: 380-7. PMID 20922767 DOI: 10.1002/Path.2767  0.301
2010 Lukic A, Beck J, Joiner S, Fearnley J, Sturman S, Brandner S, Wadsworth JD, Collinge J, Mead S. Heterozygosity at polymorphic codon 219 in variant creutzfeldt-jakob disease. Archives of Neurology. 67: 1021-3. PMID 20697057 DOI: 10.1001/Archneurol.2010.184  0.355
2010 Paisán-Ruiz C, Guevara R, Federoff M, Hanagasi H, Sina F, Elahi E, Schneider SA, Schwingenschuh P, Bajaj N, Emre M, Singleton AB, Hardy J, Bhatia KP, Brandner S, Lees AJ, et al. Early-onset L-dopa-responsive parkinsonism with pyramidal signs due to ATP13A2, PLA2G6, FBXO7 and spatacsin mutations. Movement Disorders : Official Journal of the Movement Disorder Society. 25: 1791-800. PMID 20669327 DOI: 10.1002/Mds.23221  0.324
2010 Edgeworth JA, Gros N, Alden J, Joiner S, Wadsworth JD, Linehan J, Brandner S, Jackson GS, Weissmann C, Collinge J. Spontaneous generation of mammalian prions. Proceedings of the National Academy of Sciences of the United States of America. 107: 14402-6. PMID 20660771 DOI: 10.1073/Pnas.1004036107  0.302
2010 Schott JM, Reiniger L, Thom M, Holton JL, Grieve J, Brandner S, Warren JD, Revesz T. Brain biopsy in dementia: clinical indications and diagnostic approach. Acta Neuropathologica. 120: 327-41. PMID 20640903 DOI: 10.1007/S00401-010-0721-Y  0.306
2010 Sandberg MK, Al-Doujaily H, Sigurdson CJ, Glatzel M, O'Malley C, Powell C, Asante EA, Linehan JM, Brandner S, Wadsworth JD, Collinge J. Chronic wasting disease prions are not transmissible to transgenic mice overexpressing human prion protein. The Journal of General Virology. 91: 2651-7. PMID 20610667 DOI: 10.1099/Vir.0.024380-0  0.351
2010 Urwin H, Authier A, Nielsen JE, Metcalf D, Powell C, Froud K, Malcolm DS, Holm I, Johannsen P, Brown J, Fisher EM, van der Zee J, Bruyland M, Van Broeckhoven C, ... ... Brandner S, et al. Disruption of endocytic trafficking in frontotemporal dementia with CHMP2B mutations. Human Molecular Genetics. 19: 2228-38. PMID 20223751 DOI: 10.1093/Hmg/Ddq100  0.333
2010 Jacques TS, Swales A, Brzozowski MJ, Henriquez NV, Linehan JM, Mirzadeh Z, O' Malley C, Naumann H, Alvarez-Buylla A, Brandner S. Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumour phenotypes. The Embo Journal. 29: 222-35. PMID 19927122 DOI: 10.1038/Emboj.2009.327  0.32
2010 Murphy SM, Polke JM, Manji H, Brandner S, Houlden H, Reilly MM. P59 A novel mutation in the nerve-specific 5 UTR of the Cx32 gene causing CMTX1 Neuromuscular Disorders. 20. DOI: 10.1016/S0960-8966(10)70074-2  0.305
2009 Achilli F, Bros-Facer V, Williams HP, Banks GT, AlQatari M, Chia R, Tucci V, Groves M, Nickols CD, Seburn KL, Kendall R, Cader MZ, Talbot K, van Minnen J, Burgess RW, ... Brandner S, et al. An ENU-induced mutation in mouse glycyl-tRNA synthetase (GARS) causes peripheral sensory and motor phenotypes creating a model of Charcot-Marie-Tooth type 2D peripheral neuropathy. Disease Models & Mechanisms. 2: 359-73. PMID 19470612 DOI: 10.1242/Dmm.002527  0.333
2009 Asante EA, Gowland I, Grimshaw A, Linehan JM, Smidak M, Houghton R, Osiguwa O, Tomlinson A, Joiner S, Brandner S, Wadsworth JD, Collinge J. Absence of spontaneous disease and comparative prion susceptibility of transgenic mice expressing mutant human prion proteins. The Journal of General Virology. 90: 546-58. PMID 19218199 DOI: 10.1099/Vir.0.007930-0  0.389
2008 Brandner S, Whitfield J, Boone K, Puwa A, O'Malley C, Linehan JM, Joiner S, Scaravilli F, Calder I, P Alpers M, Wadsworth JD, Collinge J. Central and peripheral pathology of kuru: pathological analysis of a recent case and comparison with other forms of human prion disease. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 363: 3755-63. PMID 18849292 DOI: 10.1098/Rstb.2008.0091  0.379
2008 Wadsworth JD, Joiner S, Linehan JM, Asante EA, Brandner S, Collinge J. Review. The origin of the prion agent of kuru: molecular and biological strain typing. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 363: 3747-53. PMID 18849291 DOI: 10.1098/Rstb.2008.0069  0.361
2008 Collinge J, Whitfield J, McKintosh E, Frosh A, Mead S, Hill AF, Brandner S, Thomas D, Alpers MP. A clinical study of kuru patients with long incubation periods at the end of the epidemic in Papua New Guinea. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 363: 3725-39. PMID 18849289 DOI: 10.1098/Rstb.2008.0068  0.307
2008 Webb TE, Poulter M, Beck J, Uphill J, Adamson G, Campbell T, Linehan J, Powell C, Brandner S, Pal S, Siddique D, Wadsworth JD, Joiner S, Alner K, Petersen C, et al. Phenotypic heterogeneity and genetic modification of P102L inherited prion disease in an international series. Brain : a Journal of Neurology. 131: 2632-46. PMID 18757886 DOI: 10.1093/Brain/Awn202  0.359
2008 O'Shea M, Maytham EG, Linehan JM, Brandner S, Collinge J, Lloyd SE. Investigation of mcp1 as a quantitative trait gene for prion disease incubation time in mouse. Genetics. 180: 559-66. PMID 18716327 DOI: 10.1534/Genetics.108.090894  0.319
2008 Isaacs AM, Powell C, Webb TE, Linehan JM, Collinge J, Brandner S. Lack of TAR-DNA binding protein-43 (TDP-43) pathology in human prion diseases. Neuropathology and Applied Neurobiology. 34: 446-56. PMID 18657254 DOI: 10.1111/J.1365-2990.2008.00963.X  0.354
2008 White MD, Farmer M, Mirabile I, Brandner S, Collinge J, Mallucci GR. Single treatment with RNAi against prion protein rescues early neuronal dysfunction and prolongs survival in mice with prion disease. Proceedings of the National Academy of Sciences of the United States of America. 105: 10238-43. PMID 18632556 DOI: 10.1073/Pnas.0802759105  0.362
2008 Wadsworth JD, Powell C, Beck JA, Joiner S, Linehan JM, Brandner S, Mead S, Collinge J. Molecular diagnosis of human prion disease. Methods in Molecular Biology (Clifton, N.J.). 459: 197-227. PMID 18576157 DOI: 10.1007/978-1-59745-234-2_14  0.372
2008 Wadsworth JD, Joiner S, Linehan JM, Desbruslais M, Fox K, Cooper S, Cronier S, Asante EA, Mead S, Brandner S, Hill AF, Collinge J. Kuru prions and sporadic Creutzfeldt-Jakob disease prions have equivalent transmission properties in transgenic and wild-type mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 3885-90. PMID 18316717 DOI: 10.1073/Pnas.0800190105  0.359
2007 Mallucci GR, White MD, Farmer M, Dickinson A, Khatun H, Powell AD, Brandner S, Jefferys JG, Collinge J. Targeting cellular prion protein reverses early cognitive deficits and neurophysiological dysfunction in prion-infected mice. Neuron. 53: 325-35. PMID 17270731 DOI: 10.1016/J.Neuron.2007.01.005  0.322
2007 Nayeem N, Kerr F, Naumann H, Linehan J, Lovestone S, Brandner S. Hyperphosphorylation of tau and neurofilaments and activation of CDK5 and ERK1/2 in PTEN-deficient cerebella. Molecular and Cellular Neurosciences. 34: 400-8. PMID 17208451 DOI: 10.1016/J.Mcn.2006.11.014  0.328
2007 Wadsworth JD, Joiner S, Fox K, Linehan JM, Desbruslais M, Brandner S, Asante EA, Collinge J. Prion infectivity in variant Creutzfeldt-Jakob disease rectum. Gut. 56: 90-4. PMID 16763054 DOI: 10.1136/Gut.2006.091637  0.342
2006 Wroe SJ, Pal S, Siddique D, Hyare H, Macfarlane R, Joiner S, Linehan JM, Brandner S, Wadsworth JD, Hewitt P, Collinge J. Clinical presentation and pre-mortem diagnosis of variant Creutzfeldt-Jakob disease associated with blood transfusion: a case report. Lancet. 368: 2061-7. PMID 17161728 DOI: 10.1016/S0140-6736(06)69835-8  0.321
2006 Asante EA, Linehan JM, Gowland I, Joiner S, Fox K, Cooper S, Osiguwa O, Gorry M, Welch J, Houghton R, Desbruslais M, Brandner S, Wadsworth JD, Collinge J. Dissociation of pathological and molecular phenotype of variant Creutzfeldt-Jakob disease in transgenic human prion protein 129 heterozygous mice. Proceedings of the National Academy of Sciences of the United States of America. 103: 10759-64. PMID 16809423 DOI: 10.1073/Pnas.0604292103  0.381
2006 Wadsworth JD, Joiner S, Linehan JM, Cooper S, Powell C, Mallinson G, Buckell J, Gowland I, Asante EA, Budka H, Brandner S, Collinge J. Phenotypic heterogeneity in inherited prion disease (P102L) is associated with differential propagation of protease-resistant wild-type and mutant prion protein. Brain : a Journal of Neurology. 129: 1557-69. PMID 16597650 DOI: 10.1093/Brain/Awl076  0.365
2005 Kristiansen M, Messenger MJ, Klöhn PC, Brandner S, Wadsworth JD, Collinge J, Tabrizi SJ. Disease-related prion protein forms aggresomes in neuronal cells leading to caspase activation and apoptosis. The Journal of Biological Chemistry. 280: 38851-61. PMID 16157591 DOI: 10.1074/Jbc.M506600200  0.337
2005 Hafezparast M, Brandner S, Linehan J, Martin JE, Collinge J, Fisher EM. Prion disease incubation time is not affected in mice heterozygous for a dynein mutation. Biochemical and Biophysical Research Communications. 326: 18-22. PMID 15567146 DOI: 10.1016/J.Bbrc.2004.10.206  0.367
2004 Wadsworth JD, Asante EA, Desbruslais M, Linehan JM, Joiner S, Gowland I, Welch J, Stone L, Lloyd SE, Hill AF, Brandner S, Collinge J. Human prion protein with valine 129 prevents expression of variant CJD phenotype. Science (New York, N.Y.). 306: 1793-6. PMID 15539564 DOI: 10.1126/Science.1103932  0.353
2004 Martins LM, Morrison A, Klupsch K, Fedele V, Moisoi N, Teismann P, Abuin A, Grau E, Geppert M, Livi GP, Creasy CL, Martin A, Hargreaves I, Heales SJ, Okada H, ... Brandner S, et al. Neuroprotective role of the Reaper-related serine protease HtrA2/Omi revealed by targeted deletion in mice. Molecular and Cellular Biology. 24: 9848-62. PMID 15509788 DOI: 10.1128/Mcb.24.22.9848-9862.2004  0.322
2004 Frosh A, Smith LC, Jackson CJ, Linehan JM, Brandner S, Wadsworth JD, Collinge J. Analysis of 2000 consecutive UK tonsillectomy specimens for disease-related prion protein. Lancet. 364: 1260-2. PMID 15464187 DOI: 10.1016/S0140-6736(04)17143-2  0.315
2004 Horstmann S, Perry A, Reifenberger G, Giangaspero F, Huang H, Hara A, Masuoka J, Rainov NG, Bergmann M, Heppner FL, Brandner S, Chimelli L, Montagna N, Jackson T, Davis DG, et al. Genetic and expression profiles of cerebellar liponeurocytomas. Brain Pathology (Zurich, Switzerland). 14: 281-9. PMID 15446583 DOI: 10.1111/J.1750-3639.2004.Tb00065.X  0.328
2004 Lloyd SE, Linehan JM, Desbruslais M, Joiner S, Buckell J, Brandner S, Wadsworth JD, Collinge J. Characterization of two distinct prion strains derived from bovine spongiform encephalopathy transmissions to inbred mice. The Journal of General Virology. 85: 2471-8. PMID 15269389 DOI: 10.1099/Vir.0.79889-0  0.338
2004 Lloyd SE, Thompson SR, Beck JA, Linehan JM, Wadsworth JD, Brandner S, Collinge J, Fisher EM. Identification and characterization of a novel mouse prion gene allele. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 15: 383-9. PMID 15170227 DOI: 10.1007/S00335-004-3041-5  0.324
2004 Anderson L, Rossi D, Linehan J, Brandner S, Weissmann C. Transgene-driven expression of the Doppel protein in Purkinje cells causes Purkinje cell degeneration and motor impairment. Proceedings of the National Academy of Sciences of the United States of America. 101: 3644-9. PMID 15007176 DOI: 10.1073/Pnas.0308681101  0.35
2003 Mallucci G, Dickinson A, Linehan J, Klöhn PC, Brandner S, Collinge J. Depleting neuronal PrP in prion infection prevents disease and reverses spongiosis. Science (New York, N.Y.). 302: 871-4. PMID 14593181 DOI: 10.1126/Science.1090187  0.334
2003 White AR, Enever P, Tayebi M, Mushens R, Linehan J, Brandner S, Anstee D, Collinge J, Hawke S. Monoclonal antibodies inhibit prion replication and delay the development of prion disease. Nature. 422: 80-3. PMID 12621436 DOI: 10.1038/Nature01457  0.334
2001 Masuoka J, Brandner S, Paulus W, Soffer D, Vital A, Chimelli L, Jouvet A, Yonekawa Y, Kleihues P, Ohgaki H. Germline SDHD mutation in paraganglioma of the spinal cord. Oncogene. 20: 5084-6. PMID 11526495 DOI: 10.1038/Sj.Onc.1204579  0.305
2001 Aguzzi A, Brandner S, Fischer MB, Furukawa H, Glatzel M, Hawkins C, Heppner FL, Montrasio F, Navarro B, Parizek P, Pekarik V, Prinz M, Raeber AJ, Röckl C, Klein MA. Spongiform encephalopathies: insights from transgenic models. Advances in Virus Research. 56: 313-52. PMID 11450305 DOI: 10.1016/S0065-3527(01)56032-7  0.357
2001 Behrens A, Brandner S, Genoud N, Aguzzi A. Normal neurogenesis and scrapie pathogenesis in neural grafts lacking the prion protein homologue Doppel. Embo Reports. 2: 347-52. PMID 11306558 DOI: 10.1093/Embo-Reports/Kve088  0.368
2001 Reis RM, Herva R, Brandner S, Koivukangas J, Mironov N, Bär W, Kleihues P, Ohgaki H. Second primary glioblastoma. Journal of Neuropathology and Experimental Neurology. 60: 208-15. PMID 11273008 DOI: 10.1093/Jnen/60.2.208  0.323
2000 Glatzel M, Klein MA, Brandner S, Aguzzi A. Prions: from neurografts to neuroinvasion. Archives of Virology. Supplementum. 3-12. PMID 11214933 DOI: 10.1007/978-3-7091-6308-5_1  0.339
2000 Aguzzi A, Klein MA, Montrasio F, Pekarik V, Brandner S, Furukawa H, Käser P, Röckl C, Glatzel M. Prions: pathogenesis and reverse genetics. Annals of the New York Academy of Sciences. 920: 140-57. PMID 11193143 DOI: 10.1111/J.1749-6632.2000.Tb06916.X  0.367
2000 Brandner S, Klein MA, Frigg R, Pekarik V, Parizek P, Raeber A, Glatzel M, Schwarz P, Rülicke T, Weissmann C, Aguzzi A. Neuroinvasion of prions: insights from mouse models. Experimental Physiology. 85: 705-12. PMID 11187965 DOI: 10.1111/J.1469-445X.2000.02091.X  0.364
2000 Brandner S, Klein MA, Aguzzi A. [Mechanisms of neuroinvasion by prions: molecular principles and present state of research]. Schweizerische Medizinische Wochenschrift. 130: 435-42. PMID 10780058 DOI: 10.5167/Uzh-1919  0.354
2000 Aguzzi A, Montrasio F, Brandner S, Frigg R, Röckl C, Fischer M, Pekarik V, Furukawa H. Molecular pathology of prion diseases Neurobiology of Aging. 21: 1. DOI: 10.1016/S0197-4580(00)82679-2  0.313
1999 Aguzzi A, Brandner S. The genetics of prions--a contradiction in terms? Lancet. 354: SI22-5. PMID 10437852 DOI: 10.1016/S0140-6736(99)90245-3  0.352
1999 Raeber AJ, Sailer A, Hegyi I, Klein MA, Rülicke T, Fischer M, Brandner S, Aguzzi A, Weissmann C. Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication. Proceedings of the National Academy of Sciences of the United States of America. 96: 3987-92. PMID 10097150 DOI: 10.1073/Pnas.96.7.3987  0.337
1998 Aguzzi A, Klein MA, Musahl C, Raeber AJ, Blättler T, Hegyi I, Frigg R, Brandner S. Use of brain grafts to study the pathogenesis of prion diseases. Essays in Biochemistry. 33: 133-47. PMID 10488447 DOI: 10.1042/Bse0330133  0.312
1998 Raeber AJ, Brandner S, Klein MA, Benninger Y, Musahl C, Frigg R, Roeckl C, Fischer MB, Weissmann C, Aguzzi A. Transgenic and knockout mice in research on prion diseases. Brain Pathology (Zurich, Switzerland). 8: 715-33. PMID 9804380 DOI: 10.1111/J.1750-3639.1998.Tb00197.X  0.348
1998 Weissmann C, Fischer M, Raeber A, Büeler H, Sailer A, Shmerling D, Rülicke T, Brandner S, Aguzzi A. The use of transgenic mice in the investigation of transmissible spongiform encephalopathies. Revue Scientifique Et Technique (International Office of Epizootics). 17: 278-90. PMID 9638817 DOI: 10.1007/978-1-4899-1896-3_7  0.334
1998 Kleinle S, Schneider V, Moosmann P, Brandner S, Krähenbühl S, Liechti-Gallati S. A novel mitochondrial tRNA(Phe) mutation inhibiting anticodon stem formation associated with a muscle disease. Biochemical and Biophysical Research Communications. 247: 112-5. PMID 9636664 DOI: 10.1006/Bbrc.1998.8729  0.301
1998 Shmerling D, Hegyi I, Fischer M, Blättler T, Brandner S, Götz J, Rülicke T, Flechsig E, Cozzio A, von Mering C, Hangartner C, Aguzzi A, Weissmann C. Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions. Cell. 93: 203-14. PMID 9568713 DOI: 10.1016/S0092-8674(00)81572-X  0.351
1998 Brandner S, Isenmann S, Kühne G, Aguzzi A. Identification of the end stage of scrapie using infected neural grafts. Brain Pathology (Zurich, Switzerland). 8: 19-27. PMID 9458163 DOI: 10.1111/J.1750-3639.1998.Tb00130.X  0.327
1997 Raeber AJ, Race RE, Brandner S, Priola SA, Sailer A, Bessen RA, Mucke L, Manson J, Aguzzi A, Oldstone MB, Weissmann C, Chesebro B. Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie. The Embo Journal. 16: 6057-65. PMID 9321385 DOI: 10.1093/Emboj/16.20.6057  0.358
1997 Blättler T, Brandner S, Raeber AJ, Klein MA, Voigtländer T, Weissmann C, Aguzzi A. PrP-expressing tissue required for transfer of scrapie infectivity from spleen to brain. Nature. 389: 69-73. PMID 9288968 DOI: 10.1038/37981  0.32
1997 Aguzzi A, Blättler T, Klein MA, Räber AJ, Hegyi I, Frigg R, Brandner S, Weissmann C. Tracking prions: the neurografting approach. Cellular and Molecular Life Sciences : Cmls. 53: 485-95. PMID 9230924 DOI: 10.1007/S000180050060  0.356
1996 Weissmann C, Fischer M, Raeber A, Büeler H, Sailer A, Shmerling D, Rülicke T, Brandner S, Aguzzi A. The role of PrP in pathogenesis of experimental scrapie. Cold Spring Harbor Symposia On Quantitative Biology. 61: 511-22. PMID 9246477 DOI: 10.1101/Sqb.1996.061.01.051  0.309
1996 Brandner S, Raeber A, Sailer A, Blättler T, Fischer M, Weissmann C, Aguzzi A. Normal host prion protein (PrPC) is required for scrapie spread within the central nervous system. Proceedings of the National Academy of Sciences of the United States of America. 93: 13148-51. PMID 8917559 DOI: 10.1073/Pnas.93.23.13148  0.343
1996 Aguzzi A, Brandner S, Marino S, Steinbach JP. Transgenic and knockout mice in the study of neurodegenerative diseases. Journal of Molecular Medicine (Berlin, Germany). 74: 111-26. PMID 8846161 DOI: 10.1007/Bf01575443  0.344
1996 Fischer M, Rülicke T, Raeber A, Sailer A, Moser M, Oesch B, Brandner S, Aguzzi A, Weissmann C. Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. The Embo Journal. 15: 1255-64. PMID 8635458 DOI: 10.1002/J.1460-2075.1996.Tb00467.X  0.332
1996 Tschopp RR, Brandner S, Marino S, Bothe K, Horak I, Rethwilm A, Aguzzi A. Analysis of the determinants of neurotropism and neurotoxicity of HFV in transgenic mice. Virology. 216: 338-46. PMID 8607263 DOI: 10.1006/Viro.1996.0069  0.308
1996 Fritschy JM, Brandner S, Aguzzi A, Koedood M, Luscher B, Mitchell PJ. Brain cell type specificity and gliosis-induced activation of the human cytomegalovirus immediate-early promoter in transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 2275-82. PMID 8601807 DOI: 10.1523/Jneurosci.16-07-02275.1996  0.325
1996 Lindberg RL, Porcher C, Grandchamp B, Ledermann B, Bürki K, Brandner S, Aguzzi A, Meyer UA. Porphobilinogen deaminase deficiency in mice causes a neuropathy resembling that of human hepatic porphyria. Nature Genetics. 12: 195-9. PMID 8563760 DOI: 10.1038/Ng0296-195  0.305
1996 Brandner S, Isenmann S, Raeber A, Fischer M, Sailer A, Kobayashi Y, Marino S, Weissmann C, Aguzzi A. Normal host prion protein necessary for scrapie-induced neurotoxicity. Nature. 379: 339-43. PMID 8552188 DOI: 10.1038/379339A0  0.33
1994 Aguzzi A, Brandner S, Sure U, Rüedi D, Isenmann S. Transgenic and knock-out mice: models of neurological disease. Brain Pathology (Zurich, Switzerland). 4: 3-20. PMID 8025701 DOI: 10.1111/J.1750-3639.1994.Tb00806.X  0.397
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