| Year |
Citation |
Score |
| 2024 |
Haufe Y, Loser D, Danker T, Nicke A. Symmetrical Bispyridinium Compounds Act as Open Channel Blockers of Cation-Selective Ion Channels. Acs Pharmacology & Translational Science. 7: 771-786. PMID 38495220 DOI: 10.1021/acsptsci.3c00308 |
0.343 |
|
| 2023 |
Haufe Y, Kuruva V, Samanani Z, Lokaj G, Kamnesky G, Shadamarshan P, Shahoei R, Katz D, Sampson JM, Pusch M, Brik A, Nicke A, Leffler AE. Basic Residues at Position 11 of α-Conotoxin LvIA Influence Subtype Selectivity between α3β2 and α3β4 Nicotinic Receptors via an Electrostatic Mechanism. Acs Chemical Neuroscience. 14: 4311-4322. PMID 38051211 DOI: 10.1021/acschemneuro.3c00506 |
0.305 |
|
| 2023 |
Souf YM, Lokaj G, Kuruva V, Saed Y, Raviglione D, Brik A, Nicke A, Inguimbert N, Dutertre S. Synthesis and Biological Activity of Novel α-Conotoxins Derived from Endemic Polynesian Cone Snails. Marine Drugs. 21. PMID 37367681 DOI: 10.3390/md21060356 |
0.339 |
|
| 2021 |
Loser D, Grillberger K, Hinojosa MG, Blum J, Haufe Y, Danker T, Johansson Y, Möller C, Nicke A, Bennekou SH, Gardner I, Bauch C, Walker P, Forsby A, Ecker GF, et al. Acute effects of the imidacloprid metabolite desnitro-imidacloprid on human nACh receptors relevant for neuronal signaling. Archives of Toxicology. PMID 34628512 DOI: 10.1007/s00204-021-03168-z |
0.355 |
|
| 2020 |
Illes P, Müller CE, Jacobson KA, Grutter T, Nicke A, Fountain SJ, Kennedy C, Schmalzing G, Jarvis MF, Stojilkovic SS, King BF, Di Virgilio F. Update of P2X receptor properties and their pharmacology: IUPHAR Review 30. British Journal of Pharmacology. PMID 33125712 DOI: 10.1111/bph.15299 |
0.362 |
|
| 2020 |
Giribaldi J, Haufe Y, Evans ERJ, Amar M, Durner A, Schmidt C, Faucherre A, Moha Ou Maati H, Enjalbal C, Molgó J, Servent D, Wilson DT, Daly NL, Nicke A, Dutertre S. Backbone Cyclization Turns a Venom Peptide into a Stable and Equipotent Ligand at Both Muscle and Neuronal Nicotinic Receptors. Journal of Medicinal Chemistry. PMID 33063995 DOI: 10.1021/acs.jmedchem.0c00957 |
0.354 |
|
| 2020 |
Conte G, Nguyen NT, Alves M, de Diego-Garcia L, Kenny A, Nicke A, Henshall DC, Jimenez-Mateos EM, Engel T. P2X7 Receptor-Dependent microRNA Expression Profile in the Brain Following Status Epilepticus in Mice. Frontiers in Molecular Neuroscience. 13: 127. PMID 32982684 DOI: 10.3389/Fnmol.2020.00127 |
0.373 |
|
| 2020 |
Koufaki M, Pournara D, Durner A, Kritsi E, Papakostas A, Zoumpoulakis P, Nicke A. Design, synthesis, and in vitro evaluation of novel P2X7 antagonists. Chemmedchem. PMID 32964578 DOI: 10.1002/Cmdc.202000303 |
0.385 |
|
| 2020 |
Wilson DT, Bansal PS, Carter DA, Vetter I, Nicke A, Dutertre S, Daly NL. Characterisation of a Novel A-Superfamily Conotoxin. Biomedicines. 8. PMID 32443665 DOI: 10.3390/Biomedicines8050128 |
0.428 |
|
| 2020 |
Wilting F, Kopp R, Gurnev PA, Schedel A, Dupper NJ, Kwon O, Nicke A, Gudermann T, Schredelseker J. The antiarrhythmic compound efsevin directly modulates voltage-dependent anion channel 2 by binding to its inner wall and enhancing mitochondrial Ca uptake. British Journal of Pharmacology. PMID 32059260 DOI: 10.1111/Bph.15022 |
0.305 |
|
| 2019 |
Kopp R, Krautloher A, Ramírez-Fernández A, Nicke A. P2X7 Interactions and Signaling - Making Head or Tail of It. Frontiers in Molecular Neuroscience. 12: 183. PMID 31440138 DOI: 10.3389/Fnmol.2019.00183 |
0.39 |
|
| 2019 |
El Hamdaoui Y, Wu X, Clark RJ, Giribaldi J, Anangi R, Craik DJ, King GF, Dutertre S, Kaas Q, Herzig V, Nicke A. Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in Favors Ribbon Isomer Formation - Suggestion of a Binding Mode at the α7 nAChR. Frontiers in Pharmacology. 10: 577. PMID 31214027 DOI: 10.3389/Fphar.2019.00577 |
0.441 |
|
| 2018 |
Kaczmarek-Hajek K, Zhang J, Kopp R, Grosche A, Rissiek B, Saul A, Bruzzone S, Engel T, Jooss T, Krautloher A, Schuster S, Magnus T, Stadelmann C, Sirko S, Koch-Nolte F, ... ... Nicke A, et al. Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody. Elife. 7. PMID 30074479 DOI: 10.7554/Elife.36217 |
0.342 |
|
| 2018 |
Giribaldi J, Wilson D, Nicke A, El Hamdaoui Y, Laconde G, Faucherre A, Moha Ou Maati H, Daly NL, Enjalbal C, Dutertre S. Synthesis, Structure and Biological Activity of CIA and CIB, Two α-Conotoxins from the Predation-Evoked Venom of . Toxins. 10. PMID 29857567 DOI: 10.3390/Toxins10060222 |
0.411 |
|
| 2018 |
Giribaldi J, Wilson D, Nicke A, Laconde G, Moha Ou Maati H, Daly NL, Enjalbal C, Dutertre S. Synthesis, structure and biological activity of CIA and CIB, two new alpha-conotoxins from Conus catus Toxicon. 149: 100. DOI: 10.1016/J.Toxicon.2018.02.017 |
0.375 |
|
| 2017 |
Leffler AE, Kuryatov A, Zebroski HA, Powell SR, Filipenko P, Hussein AK, Gorson J, Heizmann A, Lyskov S, Tsien RW, Poget SF, Nicke A, Lindstrom J, Rudy B, Bonneau R, et al. Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models. Proceedings of the National Academy of Sciences of the United States of America. PMID 28874590 DOI: 10.1073/Pnas.1703952114 |
0.44 |
|
| 2017 |
Dutertre S, Nicke A, Tsetlin V. Nicotinic acetylcholine receptor inhibitors derived from snake and snail venoms. Neuropharmacology. PMID 28623170 DOI: 10.1016/J.Neuropharm.2017.06.011 |
0.479 |
|
| 2013 |
Saul A, Hausmann R, Kless A, Nicke A. Heteromeric assembly of P2X subunits. Frontiers in Cellular Neuroscience. 7: 250. PMID 24391538 DOI: 10.3389/Fncel.2013.00250 |
0.467 |
|
| 2013 |
Hempel C, Nörenberg W, Sobottka H, Urban N, Nicke A, Fischer W, Schaefer M. The phenothiazine-class antipsychotic drugs prochlorperazine and trifluoperazine are potent allosteric modulators of the human P2X7 receptor. Neuropharmacology. 75: 365-79. PMID 23954492 DOI: 10.1016/J.Neuropharm.2013.07.027 |
0.376 |
|
| 2013 |
Bhargava Y, Nicke A, Rettinger J. Validation of Alexa-647-ATP as a powerful tool to study P2X receptor ligand binding and desensitization. Biochemical and Biophysical Research Communications. 438: 295-300. PMID 23896604 DOI: 10.1016/J.Bbrc.2013.07.058 |
0.419 |
|
| 2013 |
Kendel Y, Melaun C, Kurz A, Nicke A, Peigneur S, Tytgat J, Wunder C, Mebs D, Kauferstein S. Venomous secretions from marine snails of the Terebridae family target acetylcholine receptors. Toxins. 5: 1043-50. PMID 23698359 DOI: 10.3390/Toxins5051043 |
0.453 |
|
| 2012 |
Schwarz N, Drouot L, Nicke A, Fliegert R, Boyer O, Guse AH, Haag F, Adriouch S, Koch-Nolte F. Alternative splicing of the N-terminal cytosolic and transmembrane domains of P2X7 controls gating of the ion channel by ADP-ribosylation. Plos One. 7: e41269. PMID 22848454 DOI: 10.1371/Journal.Pone.0041269 |
0.37 |
|
| 2012 |
Beissner M, Dutertre S, Schemm R, Danker T, Sporning A, Grubmüller H, Nicke A. Efficient binding of 4/7 α-conotoxins to nicotinic α4β2 receptors is prevented by Arg185 and Pro195 in the α4 subunit. Molecular Pharmacology. 82: 711-8. PMID 22802270 DOI: 10.1124/Mol.112.078683 |
0.409 |
|
| 2012 |
Lörinczi É, Bhargava Y, Marino SF, Taly A, Kaczmarek-Hájek K, Barrantes-Freer A, Dutertre S, Grutter T, Rettinger J, Nicke A. Involvement of the cysteine-rich head domain in activation and desensitization of the P2X1 receptor. Proceedings of the National Academy of Sciences of the United States of America. 109: 11396-401. PMID 22745172 DOI: 10.1073/Pnas.1118759109 |
0.363 |
|
| 2012 |
Kaczmarek-Hájek K, Lörinczi E, Hausmann R, Nicke A. Molecular and functional properties of P2X receptors--recent progress and persisting challenges. Purinergic Signalling. 8: 375-417. PMID 22547202 DOI: 10.1007/S11302-012-9314-7 |
0.446 |
|
| 2012 |
Lörinczi E, Marino SF, Dutertre S, Bhargava Y, Rettinger J, Nicke A. Investigation of the activation and desensitization of P2X1 receptors by voltage clamp fluorometry Purinergic Signalling. 8: 152-152. PMID 22033617 DOI: 10.1007/S11302-011-9257-4 |
0.381 |
|
| 2012 |
Beissner M, Dutertre S, Schemm R, Danker T, Sporning A, Nicke A. Identification of Amino Acid Residues that Prevent Efficient Binding of 4/7 α-Conotoxins to Nicotinic α4β2 Receptor Subtypes Biophysical Journal. 102: 119a. DOI: 10.1016/J.Bpj.2011.11.667 |
0.416 |
|
| 2011 |
Kauferstein S, Porth C, Kendel Y, Wunder C, Nicke A, Kordis D, Favreau P, Koua D, Stöcklin R, Mebs D. Venomic study on cone snails (Conus spp.) from South Africa. Toxicon : Official Journal of the International Society On Toxinology. 57: 28-34. PMID 20933537 DOI: 10.1016/J.Toxicon.2010.09.009 |
0.403 |
|
| 2010 |
Marino SF, Bhargava Y, Nicke A, Rettinger J. Analysis of Structural Rearrangements during P2X1 Receptor Activation by Voltage Clamp Fluorometry Biophysical Journal. 98: 610a. DOI: 10.1016/J.Bpj.2009.12.3329 |
0.443 |
|
| 2009 |
Nicke A, Kuan YH, Masin M, Rettinger J, Marquez-Klaka B, Bender O, Górecki DC, Murrell-Lagnado RD, Soto F. A functional P2X7 splice variant with an alternative transmembrane domain 1 escapes gene inactivation in P2X7 knock-out mice. The Journal of Biological Chemistry. 284: 25813-22. PMID 19546214 DOI: 10.1074/Jbc.M109.033134 |
0.404 |
|
| 2009 |
Kauferstein S, Kendel Y, Nicke A, Coronas FI, Possani LD, Favreau P, Krizaj I, Wunder C, Kauert G, Mebs D. New conopeptides of the D-superfamily selectively inhibiting neuronal nicotinic acetylcholine receptors. Toxicon : Official Journal of the International Society On Toxinology. 54: 295-301. PMID 19393680 DOI: 10.1016/J.Toxicon.2009.04.016 |
0.497 |
|
| 2009 |
Loughnan ML, Nicke A, Lawrence N, Lewis RJ. Novel alpha D-conopeptides and their precursors identified by cDNA cloning define the D-conotoxin superfamily. Biochemistry. 48: 3717-29. PMID 19275168 DOI: 10.1021/Bi9000326 |
0.374 |
|
| 2009 |
Millard EL, Nevin ST, Loughnan ML, Nicke A, Clark RJ, Alewood PF, Lewis RJ, Adams DJ, Craik DJ, Daly NL. Inhibition of neuronal nicotinic acetylcholine receptor subtypes by alpha-Conotoxin GID and analogues. The Journal of Biological Chemistry. 284: 4944-51. PMID 19098004 DOI: 10.1074/Jbc.M804950200 |
0.704 |
|
| 2009 |
Marquez-Klaka B, Rettinger J, Nicke A. Inter-subunit disulfide cross-linking in homomeric and heteromeric P2X receptors. European Biophysics Journal : Ebj. 38: 329-38. PMID 18427801 DOI: 10.1007/S00249-008-0325-9 |
0.455 |
|
| 2009 |
Marquez-Klaka B, Nicke A, Rettinger J. Functional and biochemical evidence for an inter-subunit crosslink in the putative ATP binding site in P2X receptors Gbm Annual Spring Meeting Mosbach 2009. 2009. DOI: 10.1240/sav_gbm_2009_m_002334 |
0.307 |
|
| 2009 |
Nicke A, Brüggemann A. Use Of Isolated Vesicles From Xenopus Oocytes For Planar Patch Clamp Recordings Biophysical Journal. 96: 488a. DOI: 10.1016/J.Bpj.2008.12.2519 |
0.309 |
|
| 2008 |
Nicke A. Homotrimeric complexes are the dominant assembly state of native P2X7 subunits. Biochemical and Biophysical Research Communications. 377: 803-8. PMID 18938136 DOI: 10.1016/J.Bbrc.2008.10.042 |
0.369 |
|
| 2007 |
Dutertre S, Ulens C, Büttner R, Fish A, van Elk R, Kendel Y, Hopping G, Alewood PF, Schroeder C, Nicke A, Smit AB, Sixma TK, Lewis RJ. AChBP-targeted alpha-conotoxin correlates distinct binding orientations with nAChR subtype selectivity. The Embo Journal. 26: 3858-67. PMID 17660751 DOI: 10.1038/Sj.Emboj.7601785 |
0.506 |
|
| 2007 |
Marquez-Klaka B, Rettinger J, Bhargava Y, Eisele T, Nicke A. Identification of an intersubunit cross-link between substituted cysteine residues located in the putative ATP binding site of the P2X1 receptor. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 1456-66. PMID 17287520 DOI: 10.1523/Jneurosci.3105-06.2007 |
0.453 |
|
| 2007 |
Madry C, Mesic I, Bartholomäus I, Nicke A, Betz H, Laube B. Principal role of NR3 subunits in NR1/NR3 excitatory glycine receptor function. Biochemical and Biophysical Research Communications. 354: 102-8. PMID 17214961 DOI: 10.1016/J.Bbrc.2006.12.153 |
0.435 |
|
| 2006 |
Loughnan M, Nicke A, Jones A, Schroeder CI, Nevin ST, Adams DJ, Alewood PF, Lewis RJ. Identification of a novel class of nicotinic receptor antagonists: dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum. The Journal of Biological Chemistry. 281: 24745-55. PMID 16790424 DOI: 10.1074/Jbc.M603703200 |
0.702 |
|
| 2005 |
Dutertre S, Nicke A, Lewis RJ. Beta2 subunit contribution to 4/7 alpha-conotoxin binding to the nicotinic acetylcholine receptor. The Journal of Biological Chemistry. 280: 30460-8. PMID 15929983 DOI: 10.1074/Jbc.M504229200 |
0.47 |
|
| 2005 |
Grudzinska J, Schemm R, Haeger S, Nicke A, Schmalzing G, Betz H, Laube B. The beta subunit determines the ligand binding properties of synaptic glycine receptors. Neuron. 45: 727-39. PMID 15748848 DOI: 10.1016/J.Neuron.2005.01.028 |
0.451 |
|
| 2005 |
Nicke A, Kerschensteiner D, Soto F. Biochemical and functional evidence for heteromeric assembly of P2X1 and P2X4 subunits. Journal of Neurochemistry. 92: 925-33. PMID 15686495 DOI: 10.1111/J.1471-4159.2004.02939.X |
0.494 |
|
| 2004 |
Nicke A, Thurau H, Sadtler S, Rettinger J, Schmalzing G. Assembly of nicotinic alpha7 subunits in Xenopus oocytes is partially blocked at the tetramer level. Febs Letters. 575: 52-8. PMID 15388332 DOI: 10.1016/J.Febslet.2004.08.035 |
0.492 |
|
| 2004 |
Dutertre S, Nicke A, Tyndall JD, Lewis RJ. Determination of alpha-conotoxin binding modes on neuronal nicotinic acetylcholine receptors. Journal of Molecular Recognition : Jmr. 17: 339-47. PMID 15227641 DOI: 10.1002/Jmr.683 |
0.495 |
|
| 2004 |
Nicke A, Wonnacott S, Lewis RJ. α-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes European Journal of Biochemistry. 271: 2305-2319. PMID 15182346 DOI: 10.1111/J.1432-1033.2004.04145.X |
0.356 |
|
| 2004 |
Nicke A. Learning about structure and function of neuronal nicotinic acetylcholine receptors. Lessons from snails. European Journal of Biochemistry. 271: 2293. PMID 15182344 DOI: 10.1111/J.1432-1033.2004.04171.X |
0.389 |
|
| 2004 |
Loughnan ML, Nicke A, Jones A, Adams DJ, Alewood PF, Lewis RJ. Chemical and functional identification and characterization of novel sulfated alpha-conotoxins from the cone snail Conus anemone. Journal of Medicinal Chemistry. 47: 1234-41. PMID 14971903 DOI: 10.1021/Jm031010O |
0.564 |
|
| 2003 |
Nicke A, Samochocki M, Loughnan ML, Bansal PS, Maelicke A, Lewis RJ. Alpha-conotoxins EpI and AuIB switch subtype selectivity and activity in native versus recombinant nicotinic acetylcholine receptors. Febs Letters. 554: 219-23. PMID 14596943 DOI: 10.1016/S0014-5793(03)01161-X |
0.507 |
|
| 2003 |
Nicke A, Rettinger J, Schmalzing G. Monomeric and dimeric byproducts are the principal functional elements of higher order P2X1 concatamers. Molecular Pharmacology. 63: 243-52. PMID 12488557 DOI: 10.1124/Mol.63.1.243 |
0.409 |
|
| 2003 |
Nicke A, Loughnan ML, Millard EL, Alewood PF, Adams DJ, Daly NL, Craik DJ, Lewis RJ. Isolation, structure, and activity of GID, a novel alpha 4/7-conotoxin with an extended N-terminal sequence. The Journal of Biological Chemistry. 278: 3137-44. PMID 12419800 DOI: 10.1074/Jbc.M210280200 |
0.531 |
|
| 2003 |
Nicke A, Samochocki M, Loughnan ML, Bansal PS, Maelicke A, Lewis RJ. Corrigendum to: α-Conotoxins EpI and AuIB switch subtype selectivity and activity in native versus recombinant nicotinic acetylcholine receptors (FEBS 27779) Febs Letters. 557: 294-294. DOI: 10.1016/S0014-5793(03)01497-2 |
0.442 |
|
| 1999 |
Nicke A, Rettinger J, Büttner C, Eichele A, Lambrecht G, Schmalzing G. Evolving view of quaternary structures of ligand-gated ion channels. Progress in Brain Research. 120: 61-80. PMID 10550988 DOI: 10.1016/S0079-6123(08)63546-3 |
0.424 |
|
| 1999 |
Griffon N, Büttner C, Nicke A, Kuhse J, Schmalzing G, Betz H. Molecular determinants of glycine receptor subunit assembly. The Embo Journal. 18: 4711-21. PMID 10469650 DOI: 10.1093/Emboj/18.17.4711 |
0.478 |
|
| 1999 |
Nicke A, Rettinger J, Mutschler E, Schmalzing G. Blue native PAGE as a useful method for the analysis of the assembly of distinct combinations of nicotinic acetylcholine receptor subunits. Journal of Receptor and Signal Transduction Research. 19: 493-507. PMID 10071780 DOI: 10.3109/10799899909036667 |
0.455 |
|
| 1998 |
Nicke A, Bäumert HG, Rettinger J, Eichele A, Lambrecht G, Mutschler E, Schmalzing G. P2X1 and P2X3 receptors form stable trimers: a novel structural motif of ligand-gated ion channels. The Embo Journal. 17: 3016-28. PMID 9606184 DOI: 10.1093/Emboj/17.11.3016 |
0.495 |
|
| Show low-probability matches. |