Year |
Citation |
Score |
2024 |
Budusan E, Payne CD, Gonzalez TI, Obergrussberger A, Becker N, Clark RJ, Johan Rosengren K, Rash LD, Cristofori-Armstrong B. The funnel-web spider venom derived single knot peptide Hc3a modulates acid-sensing ion channel 1a desensitisation. Biochemical Pharmacology. 116175. PMID 38552850 DOI: 10.1016/j.bcp.2024.116175 |
0.324 |
|
2021 |
Payne CD, Vadlamani G, Hajiaghaalipour F, Muhammad T, Fisher MF, Andersson HS, Göransson U, Clark RJ, Bond CS, Mylne JS, Rosengren KJ. Solution NMR and racemic crystallography provide insights into a novel structural class of cyclic plant peptides. Rsc Chemical Biology. 2: 1682-1691. PMID 34977583 DOI: 10.1039/d1cb00155h |
0.316 |
|
2021 |
Payne CD, Franke B, Fisher MF, Hajiaghaalipour F, McAleese CE, Song A, Eliasson C, Zhang J, Jayasena AS, Vadlamani G, Clark RJ, Minchin RF, Mylne JS, Rosengren KJ. A chameleonic macrocyclic peptide with drug delivery applications. Chemical Science. 12: 6670-6683. PMID 34040741 DOI: 10.1039/d1sc00692d |
0.302 |
|
2020 |
Lee HS, Wang SH, Daniel JT, Hossain MA, Clark RJ, Bathgate RAD, Rosengren KJ. Exploring the Use of Helicogenic Amino Acids for Optimising Single Chain Relaxin-3 Peptide Agonists. Biomedicines. 8. PMID 33066369 DOI: 10.3390/biomedicines8100415 |
0.309 |
|
2020 |
Payne CD, Vadlamani G, Fisher MF, Zhang J, Clark RJ, Mylne JS, Rosengren KJ. Defining the Familial Fold of the Vicilin-Buried Peptide Family. Journal of Natural Products. PMID 32997497 DOI: 10.1021/acs.jnatprod.0c00594 |
0.31 |
|
2020 |
Li XX, Lee JD, Massey NL, Guan C, Robertson AAB, Clark RJ, Woodruff TM. Pharmacological characterisation of small molecule C5aR1 inhibitors in human cells reveals biased activities for signalling and function. Biochemical Pharmacology. 114156. PMID 32682759 DOI: 10.1016/J.Bcp.2020.114156 |
0.394 |
|
2020 |
Lee HS, Postan M, Song A, Clark RJ, Bathgate RAD, Haugaard-Kedström LM, Rosengren KJ. Development of Relaxin-3 Agonists and Antagonists Based on Grafted Disulfide-Stabilized Scaffolds. Frontiers in Chemistry. 8: 87. PMID 32133341 DOI: 10.3389/Fchem.2020.00087 |
0.4 |
|
2019 |
El Hamdaoui Y, Wu X, Clark RJ, Giribaldi J, Anangi R, Craik DJ, King GF, Dutertre S, Kaas Q, Herzig V, Nicke A. Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in Favors Ribbon Isomer Formation - Suggestion of a Binding Mode at the α7 nAChR. Frontiers in Pharmacology. 10: 577. PMID 31214027 DOI: 10.3389/Fphar.2019.00577 |
0.459 |
|
2018 |
Keov P, Liutkevičiūtė Z, Hellinger R, Clark RJ, Gruber CW. Discovery of peptide probes to modulate oxytocin-type receptors of insects. Scientific Reports. 8: 10020. PMID 29968789 DOI: 10.1038/S41598-018-28380-3 |
0.334 |
|
2018 |
Sadeghi M, Carstens BB, Callaghan BP, Daniel JT, Tae HS, O'Donnell T, Castro J, Brierley SM, Adams DJ, Craik DJ, Clark RJ. Structure-activity studies reveal the molecular basis for GABAB-receptor mediated inhibition of high voltage-activated calcium channels by α-conotoxin Vc1.1. Acs Chemical Biology. PMID 29746088 DOI: 10.1021/Acschembio.8B00190 |
0.536 |
|
2017 |
Daniel JT, Clark RJ. G-Protein Coupled Receptors Targeted by Analgesic Venom Peptides. Toxins. 9. PMID 29144441 DOI: 10.3390/Toxins9110372 |
0.381 |
|
2017 |
Daniel JT, Clark RJ. Molecular Engineering of Conus Peptides as Therapeutic Leads. Advances in Experimental Medicine and Biology. 1030: 229-254. PMID 29081056 DOI: 10.1007/978-3-319-66095-0_10 |
0.435 |
|
2016 |
Daly NL, Gunasekera S, Clark RJ, Lin F, Wade JD, Anderson MA, Craik DJ. The N-terminal pro-domain of the kalata B1 cyclotide precursor is intrinsically unstructured. Biopolymers. PMID 27564841 DOI: 10.1002/Bip.22977 |
0.345 |
|
2016 |
Zhang J, Woodruff TM, Clark RJ, Martin DJ, Minchin RF. Release of bioactive peptides from polyurethane films in vitro and in vivo: Effect of polymer composition. Acta Biomaterialia. PMID 27245428 DOI: 10.1016/J.Actbio.2016.05.034 |
0.383 |
|
2016 |
Croker DE, Monk PN, Halai R, Kaeslin G, Schofield Z, Wu MC, Clark RJ, Blaskovich MA, Morikis D, Floudas CA, Cooper MA, Woodruff TM. Discovery of functionally selective C5aR2 ligands: novel modulators of C5a signaling. Immunology and Cell Biology. PMID 27108698 DOI: 10.1038/Icb.2016.43 |
0.32 |
|
2016 |
Koehbach J, Clark RJ. Unveiling the diversity of cyclotides by combining peptidome and transcriptome analysis. Biopolymers. PMID 27106857 DOI: 10.1002/Bip.22858 |
0.378 |
|
2016 |
Carstens BB, Swedberg J, Berecki G, Adams DJ, Craik DJ, Clark RJ. Effects of linker sequence modifications on the structure, stability and biological activity of a cyclic α-conotoxin. Biopolymers. PMID 27038328 DOI: 10.1002/Bip.22848 |
0.531 |
|
2016 |
Carstens BB, Berecki G, Daniel JT, Lee HS, Jackson KA, Tae HS, Sadeghi M, Castro J, O'Donnell T, Deiteren A, Brierley SM, Craik DJ, Adams DJ, Clark RJ. Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High Voltage-Activated Calcium Channels via GABAB Receptor Activation Reveal a Minimal Functional Motif. Angewandte Chemie (International Ed. in English). PMID 26948522 DOI: 10.1002/Anie.201600297 |
0.541 |
|
2016 |
Goncalves D, Rishi G, Aliyanto R, Rosengren J, Subramaniam N, Frazer D, Clark R. Development of Peptide Therapeutics for Iron Disorders American Journal of Hematology. 91. DOI: 10.14264/Uql.2018.238 |
0.324 |
|
2015 |
Carstens BB, Rosengren KJ, Gunasekera S, Schempp S, Bohlin L, Dahlström M, Clark RJ, Göransson U. Isolation, Characterization, and Synthesis of the Barrettides: Disulfide-Containing Peptides from the Marine Sponge Geodia barretti. Journal of Natural Products. 78: 1886-93. PMID 26222779 DOI: 10.1021/Acs.Jnatprod.5B00210 |
0.44 |
|
2015 |
Akcan M, Clark RJ, Daly NL, Conibear AC, de Faoite A, Heghinian MD, Sahil T, Adams DJ, Marí F, Craik DJ. Transforming conotoxins into cyclotides: Backbone cyclization of P-superfamily conotoxins. Biopolymers. PMID 26172377 DOI: 10.1002/Bip.22699 |
0.541 |
|
2015 |
Hellinger R, Koehbach J, Puigpinós A, Clark RJ, Tarragó T, Giralt E, Gruber CW. Inhibition of Human Prolyl Oligopeptidase Activity by the Cyclotide Psysol 2 Isolated from Psychotria solitudinum. Journal of Natural Products. 78: 1073-82. PMID 25894999 DOI: 10.1021/Np501061T |
0.393 |
|
2015 |
Malik U, Silva ON, Fensterseifer IC, Chan LY, Clark RJ, Franco OL, Daly NL, Craik DJ. In vivo efficacy of anuran trypsin inhibitory peptides against staphylococcal skin infection and the impact of peptide cyclization. Antimicrobial Agents and Chemotherapy. 59: 2113-21. PMID 25624332 DOI: 10.1128/Aac.04324-14 |
0.416 |
|
2015 |
Kompella SN, Hung A, Clark RJ, Marí F, Adams DJ. Alanine scan of α-conotoxin RegIIA reveals a selective α3β4 nicotinic acetylcholine receptor antagonist. The Journal of Biological Chemistry. 290: 1039-48. PMID 25411242 DOI: 10.1074/Jbc.M114.605592 |
0.459 |
|
2014 |
Berecki G, McArthur JR, Cuny H, Clark RJ, Adams DJ. Differential Cav2.1 and Cav2.3 channel inhibition by baclofen and α-conotoxin Vc1.1 via GABAB receptor activation. The Journal of General Physiology. 143: 465-79. PMID 24688019 DOI: 10.1085/Jgp.201311104 |
0.409 |
|
2013 |
He WJ, Chan LY, Clark RJ, Tang J, Zeng GZ, Franco OL, Cantacessi C, Craik DJ, Daly NL, Tan NH. Novel inhibitor cystine knot peptides from Momordica charantia. Plos One. 8: e75334. PMID 24116036 DOI: 10.1371/Journal.Pone.0075334 |
0.434 |
|
2013 |
Grishin AA, Cuny H, Hung A, Clark RJ, Brust A, Akondi K, Alewood PF, Craik DJ, Adams DJ. Identifying key amino acid residues that affect α-conotoxin AuIB inhibition of α3β4 nicotinic acetylcholine receptors. The Journal of Biological Chemistry. 288: 34428-42. PMID 24100032 DOI: 10.1074/Jbc.M113.512582 |
0.503 |
|
2013 |
Clark RJ, Preza GC, Tan CC, van Dijk JW, Fung E, Nemeth E, Ganz T, Craik DJ. Design, synthesis, and characterization of cyclic analogues of the iron regulatory peptide hormone hepcidin. Biopolymers. 100: 519-26. PMID 23897622 DOI: 10.1002/Bip.22350 |
0.409 |
|
2013 |
Adams DJ, Berecki G, Clark R, Craik DJ. Development of analgesic alpha-conotoxins for treatment of chronic pain Clinical and Experimental Pharmacology and Physiology. 40: 4-4. DOI: 10.1111/1440-1681.12170 |
0.418 |
|
2013 |
Kompella SN, Hung A, Clark RJ, Adams DJ. α-Conotoxin Regiia Targeting Nicotinic Acetylcholine Receptors: Mutagenesis Studies Improving Selectivity and Potency Biophysical Journal. 104: 634a. DOI: 10.1016/J.Bpj.2012.11.3505 |
0.505 |
|
2012 |
Clark RJ, Craik DJ. Engineering cyclic peptide toxins Methods in Enzymology. 503: 57-74. PMID 22230565 DOI: 10.1016/B978-0-12-396962-0.00003-3 |
0.44 |
|
2012 |
Clark RJ, Akcan M, Kaas Q, Daly NL, Craik DJ. Cyclization of conotoxins to improve their biopharmaceutical properties Toxicon. 59: 446-455. PMID 21147143 DOI: 10.1016/J.Toxicon.2010.12.003 |
0.405 |
|
2011 |
Carstens BB, Clark RJ, Daly NL, Harvey PJ, Kaas Q, Craik DJ. Engineering of Conotoxins for the Treatment of Pain Current Pharmaceutical Design. 17: 4242-4253. PMID 22204425 DOI: 10.2174/138161211798999401 |
0.408 |
|
2011 |
Chan LY, Gunasekera S, Henriques ST, Worth NF, Le SJ, Clark RJ, Campbell JH, Craik DJ, Daly NL. Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds. Blood. 118: 6709-17. PMID 22039263 DOI: 10.1182/Blood-2011-06-359141 |
0.433 |
|
2011 |
Halai R, Callaghan B, Daly NL, Clark RJ, Adams DJ, Craik DJ. Effects of cyclization on stability, structure, and activity of α-conotoxin RgIA at the α9α10 nicotinic acetylcholine receptor and GABA B receptor Journal of Medicinal Chemistry. 54: 6984-6992. PMID 21888386 DOI: 10.1021/Jm201060R |
0.546 |
|
2011 |
Wang CKL, Clark RJ, Harvey PJ, Johan Rosengren K, Cemazar M, Craik DJ. The role of conserved glu residue on cyclotide stability and activity: A structural and functional study of kalata B12, a naturally occurring glu to asp mutant Biochemistry. 50: 4077-4086. PMID 21466163 DOI: 10.1021/Bi2004153 |
0.352 |
|
2011 |
Clark RJ, Tan CC, Preza GC, Nemeth E, Ganz T, Craik DJ. Understanding the structure/activity relationships of the iron regulatory peptide hepcidin. Chemistry & Biology. 18: 336-43. PMID 21439478 DOI: 10.1002/Psc.2448 |
0.325 |
|
2011 |
Haugaard-Kedström LM, Shabanpoor F, Hossain MA, Clark RJ, Ryan PJ, Craik DJ, Gundlach AL, Wade JD, Bathgate RA, Rosengren KJ. Design, synthesis, and characterization of a single-chain peptide antagonist for the relaxin-3 receptor RXFP3. Journal of the American Chemical Society. 133: 4965-74. PMID 21384867 DOI: 10.1021/Ja110567J |
0.407 |
|
2011 |
Daly NL, Callaghan B, Clark RJ, Nevin ST, Adams DJ, Craik DJ. Structure and activity of α-conotoxin PeIA at nicotinic acetylcholine receptor subtypes and GABAB receptor-coupled N-type calcium channels Journal of Biological Chemistry. 286: 10233-10237. PMID 21252227 DOI: 10.1074/Jbc.M110.196170 |
0.495 |
|
2011 |
Akcan M, Stroud MR, Hansen SJ, Clark RJ, Daly NL, Craik DJ, Olson JM. Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy. Journal of Medicinal Chemistry. 54: 782-7. PMID 21210710 DOI: 10.1021/Jm101018R |
0.331 |
|
2011 |
Lovelace ES, Gunasekera S, Alvarmo C, Clark RJ, Nevin ST, Grishin AA, Adams DJ, Craik DJ, Daly NL. Stabilization of α-conotoxin AuIB: Influences of disulfide connectivity and backbone cyclization Antioxidants and Redox Signaling. 14: 87-95. PMID 20486767 DOI: 10.1089/Ars.2009.3068 |
0.545 |
|
2011 |
Aboye TL, Clark RJ, Burman R, Roig MB, Craik DJ, Göransson U. Interlocking disulfides in circular proteins: Toward efficient oxidative folding of cyclotides Antioxidants and Redox Signaling. 14: 77-86. PMID 20486762 DOI: 10.1089/Ars.2010.3112 |
0.329 |
|
2011 |
Adams D, Grishin A, Hung A, Clark R, Akondi K, Alewood P, Craik D. Scanning mutagenesis of α-conotoxin AuIB reveals a critical residue for activity at the α3β4 nicotinic acetylcholine receptor Biochemical Pharmacology. 82: 1028. DOI: 10.1016/J.Bcp.2011.07.017 |
0.463 |
|
2010 |
Henriques ST, Tan CC, Craik DJ, Clark RJ. Structural and functional analysis of human liver-expressed antimicrobial peptide 2. Chembiochem : a European Journal of Chemical Biology. 11: 2148-57. PMID 20845358 DOI: 10.1002/Cbic.201000400 |
0.403 |
|
2010 |
Ireland DC, Clark RJ, Daly NL, Craik DJ. Isolation, sequencing, and structure - Activity relationships of cyclotides Journal of Natural Products. 73: 1610-1622. PMID 20718473 DOI: 10.1021/Np1000413 |
0.387 |
|
2010 |
Clark RJ, Craik DJ. Native chemical ligation applied to the synthesis and bioengineering of circular peptides and proteins Biopolymers. 94: 414-422. PMID 20593458 DOI: 10.1002/Bip.21372 |
0.453 |
|
2010 |
Colgrave ML, Korsinczky MJL, Clark RJ, Foley F, Craik DJ. Sunflower trypsin inhibitor-1, proteolytic studies on a trypsin inhibitor peptide and its analogs Biopolymers. 94: 665-672. PMID 20564016 DOI: 10.1002/Bip.21415 |
0.43 |
|
2010 |
Clark RJ, Jensen J, Nevin ST, Callaghan BP, Adams DJ, Craik DJ. The engineering of an orally active conotoxin for the treatment of neuropathic pain Angewandte Chemie - International Edition. 49: 6545-6548. PMID 20533477 DOI: 10.1002/Anie.201000620 |
0.502 |
|
2010 |
Huang YH, Colgrave ML, Clark RJ, Kotze AC, Craik DJ. Lysine-scanning mutagenesis reveals an amendable face of the cyclotide kalata B1 for the optimization of nematocidal activity. The Journal of Biological Chemistry. 285: 10797-805. PMID 20103593 DOI: 10.1074/Jbc.M109.089854 |
0.361 |
|
2010 |
Armishaw CJ, Singh N, Medina-Franco JL, Clark RJ, Scott KC, Houghten RA, Jensen AA. A synthetic combinatorial strategy for developing alpha-conotoxin analogs as potent alpha7 nicotinic acetylcholine receptor antagonists. The Journal of Biological Chemistry. 285: 1809-21. PMID 19901032 DOI: 10.1074/Jbc.M109.071183 |
0.413 |
|
2010 |
Clark R, Guille V, Callaghan B, Adams D, Craik D. 167 DEVELOPMENT OF AN ORALLY ACTIVE PEPTIDE FOR THE TREATMENT OF NEUROPATHIC PAIN European Journal of Pain Supplements. 4: 50-50. DOI: 10.1016/S1754-3207(10)70172-3 |
0.498 |
|
2010 |
Henriques ST, Tan CC, Craik DJ, Clark RJ. Cover Picture: Structural and Functional Analysis of Human Liver‐Expressed Antimicrobial Peptide 2 (ChemBioChem 15/2010) Chembiochem. 11: 2057-2057. DOI: 10.1002/Cbic.201090072 |
0.39 |
|
2010 |
Clark R, Jensen J, Nevin S, Callaghan B, Adams D, Craik D. Inside Cover: The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain (Angew. Chem. Int. Ed. 37/2010) Angewandte Chemie International Edition. 49: 6460-6460. DOI: 10.1002/Anie.201003933 |
0.41 |
|
2010 |
Clark R, Jensen J, Nevin S, Callaghan B, Adams D, Craik D. Innentitelbild: The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain (Angew. Chem. 37/2010) Angewandte Chemie. 122: 6606-6606. DOI: 10.1002/Ange.201003933 |
0.411 |
|
2009 |
Halai R, Clark RJ, Nevin ST, Jensen JE, Adams DJ, Craik DJ. Scanning mutagenesis of α-conotoxin Vc1.1 reveals residues crucial for activity at the α9α10 nicotinic acetylcholine receptor Journal of Biological Chemistry. 284: 20275-20284. PMID 19447885 DOI: 10.1074/Jbc.M109.015339 |
0.548 |
|
2009 |
Armishaw C, Jensen AA, Balle T, Clark RJ, Harpsøe K, Skonberg C, Liljefors T, Strømgaard K. Rational design of alpha-conotoxin analogues targeting alpha7 nicotinic acetylcholine receptors: improved antagonistic activity by incorporation of proline derivatives. The Journal of Biological Chemistry. 284: 9498-512. PMID 19131337 DOI: 10.1074/Jbc.M806136200 |
0.383 |
|
2009 |
Millard EL, Nevin ST, Loughnan ML, Nicke A, Clark RJ, Alewood PF, Lewis RJ, Adams DJ, Craik DJ, Daly NL. Inhibition of neuronal nicotinic acetylcholine receptor subtypes by alpha-Conotoxin GID and analogues. The Journal of Biological Chemistry. 284: 4944-51. PMID 19098004 DOI: 10.1074/Jbc.M804950200 |
0.504 |
|
2009 |
Gunasekera S, Daly NL, Clark RJ, Craik DJ. Dissecting the oxidative folding of circular cystine knot miniproteins. Antioxidants & Redox Signaling. 11: 971-80. PMID 19025420 DOI: 10.1089/Ars.2008.2295 |
0.363 |
|
2009 |
Halai R, Clark R, Nevin S, Adams D, Craik D. Mutational atudies on alpha-conotoxin VCL1 Biopolymers. 92: 315-315. DOI: 10.1002/Bip.21223 |
0.376 |
|
2008 |
Gunasekera S, Foley FM, Clark RJ, Sando L, Fabri LJ, Craik DJ, Daly NL. Engineering stabilized vascular endothelial growth factor-A antagonists: synthesis, structural characterization, and bioactivity of grafted analogues of cyclotides. Journal of Medicinal Chemistry. 51: 7697-704. PMID 19053834 DOI: 10.1021/Jm800704E |
0.389 |
|
2008 |
Westermann J, Clark RJ, Craik DJ. Binding Mode of α-Conotoxins to an Acetylcholine Binding Protein Determined by Saturation Transfer Difference NMR Protein and Peptide Letters. 15: 910-914. PMID 18991766 DOI: 10.2174/092986608785849335 |
0.379 |
|
2008 |
Callaghan B, Haythornthwaite A, Berecki G, Clark RJ, Craik DJ, Adams DJ. Analgesic α-conotoxins Vc1.1 and Rg1A inhibit N-type calcium channels in rat sensory neurons via GABAB receptor activation Journal of Neuroscience. 28: 10943-10951. PMID 18945902 DOI: 10.1523/Jneurosci.3594-08.2008 |
0.478 |
|
2008 |
Clark RJ, Daly NL, Halai R, Nevin ST, Adams DJ, Craik DJ. The three-dimensional structure of the analgesic α-conotoxin, RgIA Febs Letters. 582: 597-602. PMID 18242183 DOI: 10.1016/J.Febslet.2008.01.027 |
0.486 |
|
2008 |
Herrmann A, Burman R, Mylne JS, Karlsson G, Gullbo J, Craik DJ, Clark RJ, Göransson U. The alpine violet, Viola biflora, is a rich source of cyclotides with potent cytotoxicity. Phytochemistry. 69: 939-52. PMID 18191970 DOI: 10.1016/J.Phytochem.2007.10.023 |
0.328 |
|
2008 |
Leta Aboye T, Clark RJ, Craik DJ, Göransson U. Ultra-stable peptide scaffolds for protein engineering-synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2. Chembiochem : a European Journal of Chemical Biology. 9: 103-13. PMID 18058973 DOI: 10.1002/Cbic.200700357 |
0.412 |
|
2008 |
Preza G, Fernandes A, Clark RJ, Craik DJ, Ganz T, Nemeth E. Structural Aspects of Hepcidin-Ferroportin Binding Blood. 112: 119-119. DOI: 10.1182/Blood.V112.11.119.119 |
0.321 |
|
2008 |
Aboye TL, Clark RJ, Craik DJ, Goransson U. Synthesis and folding of the circular cystine knotted cyclotide cycloviolacin O2. Planta Medica. 74: 1158-1158. DOI: 10.1055/S-0028-1084795 |
0.396 |
|
2008 |
Aboye TL, Clark RJ, Craik DJ, Göransson U. Cover Picture: Ultra‐Stable Peptide Scaffolds for Protein Engineering—Synthesis and Folding of the Circular Cystine Knotted Cyclotide Cycloviolacin O2 (ChemBioChem 1/2008) Chembiochem. 9: 1-1. DOI: 10.1002/Cbic.200790068 |
0.355 |
|
2007 |
Nevin ST, Clark RJ, Klimis H, Christie MJ, Craik DJ, Adams DJ. Are alpha9alpha10 nicotinic acetylcholine receptors a pain target for alpha-conotoxins? Molecular Pharmacology. 72: 1406-10. PMID 17804600 DOI: 10.1124/Mol.107.040568 |
0.514 |
|
2007 |
Plan MR, Göransson U, Clark RJ, Daly NL, Colgrave ML, Craik DJ. The cyclotide fingerprint in oldenlandia affinis: elucidation of chemically modified, linear and novel macrocyclic peptides. Chembiochem : a European Journal of Chemical Biology. 8: 1001-11. PMID 17534989 DOI: 10.1002/Cbic.200700097 |
0.397 |
|
2007 |
Gruber CW, Čemažar M, Clark RJ, Horibe T, Renda RF, Anderson MA, Craik DJ. A novel plant protein-disulfide isomerase involved in the oxidative folding of cystine knot defense proteins Journal of Biological Chemistry. 282: 20435-20446. PMID 17522051 DOI: 10.1074/Jbc.M700018200 |
0.301 |
|
2007 |
Craik DJ, Clark RJ, Daly NL. Potential therapeutic applications of the cyclotides and related cystine knot mini-proteins Expert Opinion On Investigational Drugs. 16: 595-604. PMID 17461734 DOI: 10.1517/13543784.16.5.595 |
0.416 |
|
2007 |
Jin AH, Brandstaetter H, Nevin ST, Tan CC, Clark RJ, Adams DJ, Alewood PF, Craik DJ, Daly NL. Structure of alpha-conotoxin BuIA: influences of disulfide connectivity on structural dynamics. Bmc Structural Biology. 7: 28. PMID 17445276 DOI: 10.1186/1472-6807-7-28 |
0.448 |
|
2007 |
Gruber GW, Cemazar M, Clark R, Horibe T, Renda R, Anderson MA, Craik DJ. Enzyme mechanism and function of a novel plant protein disulfide isomerase involved in the oxidative folding of cystine knot defence peptides Biopolymers. 88: 541-541. DOI: 10.1002/Bip.20783 |
0.357 |
|
2006 |
Daly NL, Chen Y, Foley FM, Bansal PS, Bharathi R, Clark RJ, Sommerhoff CP, Craik DJ. The Absolute Structural Requirement for a Proline in the P3′-position of Bowman-Birk Protease Inhibitors Is Surmounted in the Minimized SFTI-1 Scaffold Journal of Biological Chemistry. 281: 23668-23675. PMID 16766795 DOI: 10.1074/Jbc.M601426200 |
0.432 |
|
2006 |
Clark RJ, Fischer H, Nevin ST, Adams DJ, Craik DJ. The synthesis, structural characterization, and receptor specificity of the α-conotoxin Vc1.1 Journal of Biological Chemistry. 281: 23254-23263. PMID 16754662 DOI: 10.1074/Jbc.M604550200 |
0.542 |
|
2006 |
Clark RJ, Daly NL, Craik DJ. Structural plasticity of the cyclic-cystine-knot framework: implications for biological activity and drug design. Biochemical Journal. 394: 85-93. PMID 16300479 DOI: 10.1042/Bj20051691 |
0.441 |
|
2006 |
Daly NL, Clark RJ, Plan MR, Craik DJ. Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif Biochemical Journal. 393: 619-626. PMID 16207177 DOI: 10.1042/Bj20051371 |
0.404 |
|
2005 |
Clark RJ, Fischer H, Dempster L, Daly NL, Rosengren KJ, Nevin ST, Meunier FA, Adams DJ, Craik DJ. Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the α-conotoxin MII Proceedings of the National Academy of Sciences of the United States of America. 102: 13767-13772. PMID 16162671 DOI: 10.1073/Pnas.0504613102 |
0.561 |
|
2005 |
Korsinczky MLJ, Clark RJ, Craik DJ. Disulfide bond mutagenesis and the structure and function of the head-to-tail macrocyclic trypsin inhibitor SFTI-1 Biochemistry. 44: 1145-1153. PMID 15667208 DOI: 10.1021/Bi048297R |
0.375 |
|
2004 |
Dutton JL, Renda RF, Waine C, Clark RJ, Daly NL, Jennings CV, Anderson MA, Craik DJ. Conserved structural and sequence elements implicated in the processing of gene-encoded circular proteins. The Journal of Biological Chemistry. 279: 46858-67. PMID 15328347 DOI: 10.1074/Jbc.M407421200 |
0.364 |
|
2004 |
Rosengren J, Jen F, Clark R, Daly N, Göransson U, Jones A, Craik D. A novel threaded ring structure for the antimicrobial peptide microcin J25 Journal of Peptide Science. 10: 116-116. DOI: 10.1002/Psc.617 |
0.404 |
|
2003 |
Rosengren KJ, Clark RJ, Daly NL, Göransson U, Jones A, Craik DJ. Microcin J25 has a threaded sidechain-to-backbone ring structure and not a head-to-tail cyclized backbone. Journal of the American Chemical Society. 125: 12464-74. PMID 14531690 DOI: 10.1021/Ja0367703 |
0.423 |
|
2003 |
Daly NL, Clark RJ, Craik DJ. Disulfide folding pathways of cystine knot proteins: Tying the knot within the circular backbone of the cyclotides Journal of Biological Chemistry. 278: 6314-6322. PMID 12482862 DOI: 10.1074/Jbc.M210492200 |
0.356 |
|
2003 |
Craik DJ, Barry DG, Clark RJ, Daly NL, Sando L. Structure‐Function Studies of the Plant Cyclotides: The Role of a Circular Protein Backbone Journal of Toxicology-Toxin Reviews. 22: 555-576. DOI: 10.1081/Txr-120026914 |
0.339 |
|
2003 |
daly NL, clark RJ, Göransson U, craik DJ. Diversity in the disulfide folding pathways of cystine knot peptides Letters in Peptide Science. 10: 523-531. DOI: 10.1007/Bf02442584 |
0.418 |
|
2001 |
Craik DJ, Anderson MA, Barry DG, Clark RJ, Daly NL, Jennings CV, Mulvenna JP. Discovery and structures of the cyclotides: novel macrocyclic peptides from plants Letters in Peptide Science. 8: 119-128. DOI: 10.1007/Bf02446507 |
0.385 |
|
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