| Year |
Citation |
Score |
| 2023 |
Daly C, Guseinov AA, Hahn H, Wright A, Tikhonova IG, Thomsen ARB, Plouffe B. β-Arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor. Elife. 12. PMID 37855711 DOI: 10.7554/eLife.87754 |
0.529 |
|
| 2023 |
Daly C, Plouffe B. Gα signalling from endosomes: A new conundrum. British Journal of Pharmacology. PMID 37740273 DOI: 10.1111/bph.16248 |
0.527 |
|
| 2023 |
Daly C, Guseinov AA, Hahn H, Tikhonova IG, Thomsen ARB, Plouffe B. β-arrestin-dependent and -independent endosomal G protein activation by the vasopressin type 2 receptor. Biorxiv : the Preprint Server For Biology. PMID 37034816 DOI: 10.1101/2023.04.01.535208 |
0.453 |
|
| 2022 |
Plouffe B, Karamitri A, Flock T, Gallion JM, Houston S, Daly CA, Bonnefond A, Guillaume JL, Le Gouill C, Froguel P, Lichtarge O, Deupi X, Jockers R, Bouvier M. Structural Elements Directing G Proteins and β-Arrestin Interactions with the Human Melatonin Type 2 Receptor Revealed by Natural Variants. Acs Pharmacology & Translational Science. 5: 89-101. PMID 35846981 DOI: 10.1021/acsptsci.1c00239 |
0.648 |
|
| 2022 |
Heydenreich FM, Plouffe B, Rizk A, Milic D, Zhou J, Breton B, Le Gouill C, Inoue A, Bouvier M, Veprintsev D. . Molecular Pharmacology. PMID 35779859 DOI: 10.1124/molpharm.122.000497 |
0.66 |
|
| 2021 |
Hegron A, Huh E, Deupi X, Sokrat B, Gao W, Le Gouill C, Canouil M, Boissel M, Charpentier G, Roussel R, Balkau B, Froguel P, Plouffe B, Bonnefond A, Lichtarge O, et al. Identification of Key Regions Mediating Human Melatonin Type 1 Receptor Functional Selectivity Revealed by Natural Variants. Acs Pharmacology & Translational Science. 4: 1614-1627. PMID 34661078 DOI: 10.1021/acsptsci.1c00157 |
0.785 |
|
| 2021 |
Brouwers B, de Oliveira EM, Marti-Solano M, Monteiro FBF, Laurin SA, Keogh JM, Henning E, Bounds R, Daly CA, Houston S, Ayinampudi V, Wasiluk N, Clarke D, Plouffe B, Bouvier M, et al. Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation. Cell Reports. 34: 108862. PMID 33761344 DOI: 10.1016/j.celrep.2021.108862 |
0.686 |
|
| 2020 |
Imam A, Winnebeck EC, Buchholz N, Froguel P, Bonnefond A, Solimena M, Ivanova A, Bouvier M, Plouffe B, Charpentier G, Karamitri A, Jockers R, Roenneberg T, Vetter C. Circadian, Sleep and Caloric Intake Phenotyping in Type 2 Diabetes Patients With Rare Melatonin Receptor 2 Mutations and Controls: A Pilot Study. Frontiers in Physiology. 11: 564140. PMID 33162895 DOI: 10.3389/fphys.2020.564140 |
0.437 |
|
| 2020 |
Daly CA, Smit MJ, Plouffe B. The constitutive activity of the viral-encoded G protein-coupled receptor US28 supports a complex signalling network contributing to cancer development. Biochemical Society Transactions. PMID 32779712 DOI: 10.1042/Bst20190988 |
0.448 |
|
| 2020 |
Plouffe B, Thomsen ARB, Irannejad R. Emerging Role of Compartmentalized G Protein-Coupled Receptor Signaling in the Cardiovascular Field. Acs Pharmacology & Translational Science. 3: 221-236. PMID 32296764 DOI: 10.1021/acsptsci.0c00006 |
0.562 |
|
| 2020 |
Imam A, Winnebeck EC, Buchholz N, Froguel P, Bonnefond A, Solimena M, Ivanova A, Bouvier M, Plouffe B, Charpentier G, Karamitri A, Jockers R, Roenneberg T, Vetter C. Circadian, Sleep and Caloric Intake Phenotyping in Type 2 Diabetes Patients With Rare Melatonin Receptor 2 Mutations and Controls: A Pilot Study Frontiers in Physiology. 11. DOI: 10.3389/fphys.2020.564140 |
0.448 |
|
| 2019 |
Imam A, Winnebeck E, Buchholz N, Froguel P, Bonnefond A, Solimena M, Ivanova A, Bouvier M, Plouffe B, Charpentier G, Karamitri A, Jockers R, Roenneberg T, Vetter C. Functional circadian and sleep phenotyping of type 2 diabetes patients with melatonin receptor 2 mutations and controls: a pilot study Sleep Medicine. 64: S166-S167. DOI: 10.1016/j.sleep.2019.11.460 |
0.454 |
|
| 2018 |
Mende F, Hundahl C, Plouffe B, Skov LJ, Sivertsen B, Madsen AN, Lückmann M, Diep TA, Offermanns S, Frimurer TM, Bouvier M, Holst B. Translating biased signaling in the ghrelin receptor system into differential in vivo functions. Proceedings of the National Academy of Sciences of the United States of America. PMID 30301804 DOI: 10.1073/Pnas.1804003115 |
0.702 |
|
| 2018 |
Luttrell LM, Wang J, Plouffe B, Smith JS, Yamani L, Kaur S, Jean-Charles PY, Gauthier C, Lee MH, Pani B, Kim J, Ahn S, Rajagopal S, Reiter E, Bouvier M, et al. Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9. Science Signaling. 11. PMID 30254056 DOI: 10.1126/Scisignal.Aat7650 |
0.741 |
|
| 2018 |
Karamitri A, Plouffe B, Bonnefond A, Chen M, Gallion J, Guillaume JL, Hegron A, Boissel M, Canouil M, Langenberg C, Wareham NJ, Le Gouill C, Lukasheva V, Lichtarge O, Froguel P, et al. Type 2 diabetes-associated variants of the MT melatonin receptor affect distinct modes of signaling. Science Signaling. 11. PMID 30154102 DOI: 10.1126/Scisignal.Aan6622 |
0.784 |
|
| 2017 |
Stallaert W, van der Westhuizen ET, Schonegge AM, Plouffe B, Hogue M, Lukashova V, Inoue A, Ishida S, Aoki J, Le Gouill C, Bouvier M. Purinergic receptor transactivation by the β2-adrenergic receptor increases intracellular Ca(2+) in non-excitable cells. Molecular Pharmacology. PMID 28280061 DOI: 10.1124/Mol.116.106419 |
0.732 |
|
| 2017 |
Möller D, Banerjee A, Uzuneser TC, Skultety M, Huth T, Plouffe B, Hübner H, Alzheimer C, Friedland K, Müller CP, Bouvier M, Gmeiner P. Discovery of G Protein-Biased Dopaminergics with a Pyrazolo[1,5-a]pyridine Substructure. Journal of Medicinal Chemistry. PMID 28248104 DOI: 10.1021/Acs.Jmedchem.6B01857 |
0.663 |
|
| 2017 |
Cahill TJ, Thomsen AR, Tarrasch JT, Plouffe B, Nguyen AH, Yang F, Huang LY, Kahsai AW, Bassoni DL, Gavino BJ, Lamerdin JE, Triest S, Shukla AK, Berger B, Little J, et al. Distinct conformations of GPCR-β-arrestin complexes mediate desensitization, signaling, and endocytosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28223524 DOI: 10.1073/Pnas.1701529114 |
0.731 |
|
| 2017 |
Cahill T, Thomsen A, Plouffe B, Bouvier M, Lefkowitz R. LB987 New insights into gpcr-transducer coupling Journal of Investigative Dermatology. 137: B10. DOI: 10.1016/J.Jid.2017.07.067 |
0.591 |
|
| 2016 |
Thomsen AR, Plouffe B, Cahill TJ, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, et al. GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling. Cell. PMID 27499021 DOI: 10.1016/J.Cell.2016.07.004 |
0.758 |
|
| 2016 |
Bradley SJ, Wiegman CH, Iglesias MM, Kong KC, Butcher AJ, Plouffe B, Goupil E, Bourgognon JM, Macedo-Hatch T, LeGouill C, Russell K, Laporte SA, König GM, Kostenis E, Bouvier M, et al. Mapping physiological G protein-coupled receptor signaling pathways reveals a role for receptor phosphorylation in airway contraction. Proceedings of the National Academy of Sciences of the United States of America. PMID 27071102 DOI: 10.1073/Pnas.1521706113 |
0.652 |
|
| 2014 |
Zhang B, Albaker A, Plouffe B, Lefebvre C, Tiberi M. Constitutive activities and inverse agonism in dopamine receptors Advances in Pharmacology. 70: 175-214. PMID 24931197 DOI: 10.1016/B978-0-12-417197-8.00007-9 |
0.486 |
|
| 2013 |
Plouffe B, Tiberi M. Functional analysis of human D1 and D5 dopaminergic G protein-coupled receptors: lessons from mutagenesis of a conserved serine residue in the cytosolic end of transmembrane region 6. Methods in Molecular Biology (Clifton, N.J.). 964: 141-80. PMID 23296783 DOI: 10.1007/978-1-62703-251-3_10 |
0.445 |
|
| 2012 |
Plouffe B, Yang X, Tiberi M. The third intracellular loop of D1 and D5 dopaminergic receptors dictates their subtype-specific PKC-induced sensitization and desensitization in a receptor conformation-dependent manner. Cellular Signalling. 24: 106-18. PMID 21893192 DOI: 10.1016/j.cellsig.2011.08.008 |
0.341 |
|
| 2010 |
Mahalingam AK, Wan Y, Murugaiah AM, Wallinder C, Wu X, Plouffe B, Botros M, Nyberg F, Hallberg A, Gallo-Payet N, Alterman M. Selective angiotensin II AT(2) receptor agonists with reduced CYP 450 inhibition. Bioorganic & Medicinal Chemistry. 18: 4570-90. PMID 20493713 DOI: 10.1016/J.Bmc.2010.03.064 |
0.312 |
|
| 2006 |
Wu X, Wan Y, Mahalingam AK, Murugaiah AM, Plouffe B, Botros M, Karlén A, Hallberg M, Gallo-Payet N, Alterman M. Selective angiotensin II AT2 receptor agonists: arylbenzylimidazole structure-activity relationships. Journal of Medicinal Chemistry. 49: 7160-8. PMID 17125268 DOI: 10.1021/Jm0606185 |
0.313 |
|
| 2005 |
Georgsson J, Sköld C, Plouffe B, Lindeberg G, Botros M, Larhed M, Nyberg F, Gallo-Payet N, Gogoll A, Karlén A, Hallberg A. Angiotensin II pseudopeptides containing 1,3,5-trisubstituted benzene scaffolds with high AT2 receptor affinity Journal of Medicinal Chemistry. 48: 6620-6631. PMID 16220978 DOI: 10.1021/Jm050280Z |
0.325 |
|
| 2005 |
Rosenström U, Sköld C, Plouffe B, Beaudry H, Lindeberg G, Botros M, Nyberg F, Wolf G, Karlén A, Gallo-Payet N, Hallberg A. New selective AT2 receptor ligands encompassing a gamma-turn mimetic replacing the amino acid residues 4-5 of angiotensin II act as agonists. Journal of Medicinal Chemistry. 48: 4009-24. PMID 15943474 DOI: 10.1021/Jm0491492 |
0.308 |
|
| 2004 |
Wan Y, Wallinder C, Plouffe B, Beaudry H, Mahalingam AK, Wu X, Johansson B, Holm M, Botoros M, Karlén A, Pettersson A, Nyberg F, Fändriks L, Gallo-Payet N, Hallberg A, et al. Design, synthesis, and biological evaluation of the first selective nonpeptide AT2 receptor agonist. Journal of Medicinal Chemistry. 47: 5995-6008. PMID 15537354 DOI: 10.1021/Jm049715T |
0.303 |
|
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