Year |
Citation |
Score |
2024 |
Pakharukova N, Thomas BN, Bansia H, Li L, Abzalimov RR, Kim J, Kahsai AW, Pani B, Bassford DK, Liu S, Zhang X, des Georges A, Lefkowitz RJ. Beta-arrestin 1 mediated Src activation via Src SH3 domain revealed by cryo-electron microscopy. Biorxiv : the Preprint Server For Biology. PMID 39131402 DOI: 10.1101/2024.07.31.605623 |
0.821 |
|
2024 |
Casiraghi M, Wang H, Brennan P, Habrian C, Hübner H, Schmidt MF, Maul L, Pani B, Bahriz SMFM, Xu B, White E, Sunahara RK, Xiang YK, Lefkowitz RJ, Isacoff EY, et al. Molecular insights into G protein specificity and biased agonism at the β -adrenergic receptor. Biorxiv : the Preprint Server For Biology. PMID 38586060 DOI: 10.1101/2024.03.28.587240 |
0.714 |
|
2023 |
Lefkowitz RJ, Rockman HA, Shim PJ, Liu S, Ahn S, Pani B, Rajagopal S, Shenoy SK, Bouvier M, Benovic JL, Liggett SB, Ruffolo RR, Bristow MR, Packer M. How carvedilol does not activate β-adrenoceptors. Nature Communications. 14: 7866. PMID 38036531 DOI: 10.1038/s41467-023-42848-5 |
0.797 |
|
2021 |
Pani B, Ahn S, Rambarat PK, Vege S, Kahsai AW, Liu A, Valan BN, Staus DP, Costa T, Lefkowitz RJ. . Molecular Pharmacology. PMID 34580163 DOI: 10.1124/molpharm.121.000363 |
0.839 |
|
2021 |
Wang J, Pani B, Gokhan I, Xiong X, Kahsai AW, Jiang H, Ahn S, Lefkowitz RJ, Rockman HA. β-arrestin-biased allosteric modulator potentiates Carvedilol stimulated β adrenergic receptor cardioprotection. Molecular Pharmacology. PMID 34561298 DOI: 10.1124/molpharm.121.000359 |
0.74 |
|
2020 |
Pakharukova N, Masoudi A, Pani B, Staus DP, Lefkowitz RJ. Allosteric activation of proto-oncogene kinase Src by GPCR-beta-arrestin complexes. The Journal of Biological Chemistry. 295: 16773-16784. PMID 33453910 DOI: 10.1074/jbc.RA120.015400 |
0.651 |
|
2020 |
Pakharukova N, Masoudi A, Pani B, Staus DP, Lefkowitz RJ. Allosteric activation of proto-oncogene kinase Src by GPCR-beta-arrestin complexes. The Journal of Biological Chemistry. PMID 32978252 DOI: 10.1074/jbc.RA120.015400 |
0.828 |
|
2019 |
Liu X, Masoudi A, Kahsai AW, Huang LY, Pani B, Staus DP, Shim PJ, Hirata K, Simhal RK, Schwalb AM, Rambarat PK, Ahn S, Lefkowitz RJ, Kobilka B. Mechanism of βAR regulation by an intracellular positive allosteric modulator. Science (New York, N.Y.). 364: 1283-1287. PMID 31249059 DOI: 10.1126/science.aaw8981 |
0.843 |
|
2019 |
Liu X, Masoudi A, Kahsai AW, Huang L, Pani B, Staus DP, Shim PJ, Hirata K, Simhal RK, Schwalb AM, Rambarat PK, Ahn S, Lefkowitz RJ, Kobilka B. Mechanism of beta2AR regulation by an intracellular positive allosteric modulator. Science. 364: 1283-1287. DOI: 10.2210/Pdb6N48/Pdb |
0.848 |
|
2018 |
Luttrell LM, Wang J, Plouffe B, Smith JS, Yamani L, Kaur S, Jean-Charles PY, Gauthier C, Lee MH, Pani B, Kim J, Ahn S, Rajagopal S, Reiter E, Bouvier M, et al. Manifold roles of β-arrestins in GPCR signaling elucidated with siRNA and CRISPR/Cas9. Science Signaling. 11. PMID 30254056 DOI: 10.1126/Scisignal.Aat7650 |
0.837 |
|
2018 |
Choi M, Staus DP, Wingler LM, Ahn S, Pani B, Capel WD, Lefkowitz RJ. G protein-coupled receptor kinases (GRKs) orchestrate biased agonism at the β-adrenergic receptor. Science Signaling. 11. PMID 30131371 DOI: 10.1126/Scisignal.Aar7084 |
0.828 |
|
2018 |
Kahsai AW, Pani B, Lefkowitz RJ. GPCR signaling: conformational activation of arrestins. Cell Research. PMID 30030517 DOI: 10.1038/S41422-018-0067-X |
0.558 |
|
2018 |
Ahn S, Pani B, Kahsai AW, Olsen EK, Husemoen G, Vestrgaard M, Jin L, Zhao S, Wingler LM, Rambarat PK, Simhal RK, Xu TT, Sun LD, Shim PJ, Staus DP, et al. Small Molecule Positive Allosteric Modulators of the β-Adrenoceptor Isolated from DNA Encoded Libraries. Molecular Pharmacology. PMID 29769246 DOI: 10.1124/Mol.118.111948 |
0.824 |
|
2018 |
Staus DP, Wingler LM, Choi M, Pani B, Manglik A, Kruse AC, Lefkowitz RJ. Sortase ligation enables homogeneous GPCR phosphorylation to reveal diversity in β-arrestin coupling. Proceedings of the National Academy of Sciences of the United States of America. PMID 29581292 DOI: 10.1073/Pnas.1722336115 |
0.841 |
|
2017 |
Bollimuntha S, Pani B, Singh BB. Neurological and Motor Disorders: Neuronal Store-Operated Ca(2+) Signaling: An Overview and Its Function. Advances in Experimental Medicine and Biology. 993: 535-556. PMID 28900932 DOI: 10.1007/978-3-319-57732-6_27 |
0.769 |
|
2017 |
Liu X, Ahn S, Kahsai AW, Meng KC, Latorraca NR, Pani B, Venkatakrishnan AJ, Masoudi A, Weis WI, Dror RO, Chen X, Lefkowitz RJ, Kobilka BK. Mechanism of intracellular allosteric β2AR antagonist revealed by X-ray crystal structure. Nature. PMID 28813418 DOI: 10.1038/Nature23652 |
0.857 |
|
2017 |
Ahn S, Kahsai AW, Pani B, Wang QT, Zhao S, Wall AL, Strachan RT, Staus DP, Wingler LM, Sun LD, Sinnaeve J, Choi M, Cho T, Xu TT, Hansen GM, et al. Allosteric "beta-blocker" isolated from a DNA-encoded small molecule library. Proceedings of the National Academy of Sciences of the United States of America. PMID 28130548 DOI: 10.1073/Pnas.1620645114 |
0.81 |
|
2016 |
Thomsen AR, Plouffe B, Cahill TJ, Shukla AK, Tarrasch JT, Dosey AM, Kahsai AW, Strachan RT, Pani B, Mahoney JP, Huang L, Breton B, Heydenreich FM, Sunahara RK, Skiniotis G, et al. GPCR-G Protein-β-Arrestin Super-Complex Mediates Sustained G Protein Signaling. Cell. PMID 27499021 DOI: 10.1016/J.Cell.2016.07.004 |
0.828 |
|
2016 |
Staus DP, Strachan RT, Manglik A, Pani B, Kahsai AW, Kim TH, Wingler LM, Ahn S, Chatterjee A, Masoudi A, Kruse AC, Pardon E, Steyaert J, Weis WI, Prosser RS, et al. Allosteric nanobodies reveal the dynamic range and diverse mechanisms of G-protein-coupled receptor activation. Nature. PMID 27409812 DOI: 10.1038/Nature18636 |
0.81 |
|
2016 |
Kahsai AW, Wisler JW, Lee J, Ahn S, Cahill Iii TJ, Dennison SM, Staus DP, Thomsen AR, Anasti KM, Pani B, Wingler LM, Desai H, Bompiani KM, Strachan RT, Qin X, et al. Conformationally selective RNA aptamers allosterically modulate the β2-adrenoceptor. Nature Chemical Biology. PMID 27398998 DOI: 10.1038/Nchembio.2126 |
0.821 |
|
2014 |
Chauhan A, Sun Y, Pani B, Quenumzangbe F, Sharma J, Singh BB, Mishra BB. Helminth induced suppression of macrophage activation is correlated with inhibition of calcium channel activity. Plos One. 9: e101023. PMID 25013939 DOI: 10.1371/Journal.Pone.0101023 |
0.605 |
|
2013 |
Pani B, Liu X, Bollimuntha S, Cheng KT, Niesman IR, Zheng C, Achen VR, Patel HH, Ambudkar IS, Singh BB. Impairment of TRPC1-STIM1 channel assembly and AQP5 translocation compromise agonist-stimulated fluid secretion in mice lacking caveolin1. Journal of Cell Science. 126: 667-75. PMID 23203809 DOI: 10.1242/Jcs.118943 |
0.782 |
|
2012 |
Pani B, Bollimuntha S, Singh BB. The TR (i)P to Ca²⁺ signaling just got STIMy: an update on STIM1 activated TRPC channels. Frontiers in Bioscience (Landmark Edition). 17: 805-23. PMID 22201775 DOI: 10.2741/3958 |
0.765 |
|
2010 |
Liu X, Ong HL, Pani B, Johnson K, Swaim WB, Singh B, Ambudkar I. Effect of cell swelling on ER/PM junctional interactions and channel assembly involved in SOCE. Cell Calcium. 47: 491-9. PMID 20488539 DOI: 10.1016/J.Ceca.2010.04.002 |
0.595 |
|
2009 |
Pani B, Ong HL, Brazer SC, Liu X, Rauser K, Singh BB, Ambudkar IS. Activation of TRPC1 by STIM1 in ER-PM microdomains involves release of the channel from its scaffold caveolin-1. Proceedings of the National Academy of Sciences of the United States of America. 106: 20087-92. PMID 19897728 DOI: 10.1073/Pnas.0905002106 |
0.613 |
|
2009 |
Pani B, Singh BB. Lipid rafts/caveolae as microdomains of calcium signaling. Cell Calcium. 45: 625-33. PMID 19324409 DOI: 10.1016/J.Ceca.2009.02.009 |
0.614 |
|
2008 |
Pani B, Ong HL, Liu X, Rauser K, Ambudkar IS, Singh BB. Lipid rafts determine clustering of STIM1 in endoplasmic reticulum-plasma membrane junctions and regulation of store-operated Ca2+ entry (SOCE). The Journal of Biological Chemistry. 283: 17333-40. PMID 18430726 DOI: 10.1074/Jbc.M800107200 |
0.585 |
|
2008 |
Pani B, Singh BB. Darier's disease: a calcium-signaling perspective. Cellular and Molecular Life Sciences : Cmls. 65: 205-11. PMID 18049860 DOI: 10.1007/S00018-007-7397-Z |
0.605 |
|
2007 |
Liu X, Cheng KT, Bandyopadhyay BC, Pani B, Dietrich A, Paria BC, Swaim WD, Beech D, Yildrim E, Singh BB, Birnbaumer L, Ambudkar IS. Attenuation of store-operated Ca2+ current impairs salivary gland fluid secretion in TRPC1(-/-) mice. Proceedings of the National Academy of Sciences of the United States of America. 104: 17542-7. PMID 17956991 DOI: 10.1073/Pnas.0701254104 |
0.619 |
|
2007 |
Ong HL, Cheng KT, Liu X, Bandyopadhyay BC, Paria BC, Soboloff J, Pani B, Gwack Y, Srikanth S, Singh BB, Gill DL, Gill D, Ambudkar IS. Dynamic assembly of TRPC1-STIM1-Orai1 ternary complex is involved in store-operated calcium influx. Evidence for similarities in store-operated and calcium release-activated calcium channel components. The Journal of Biological Chemistry. 282: 9105-16. PMID 17224452 DOI: 10.1074/Jbc.M608942200 |
0.608 |
|
2006 |
Pani B, Cornatzer E, Cornatzer W, Shin DM, Pittelkow MR, Hovnanian A, Ambudkar IS, Singh BB. Up-regulation of transient receptor potential canonical 1 (TRPC1) following Sarco(endo)plasmic Reticulum Ca2+ ATPase 2 gene silencing promotes cell survival: A potential role for TRPC1 in Darier's disease Molecular Biology of the Cell. 17: 4446-4458. PMID 16899508 DOI: 10.1091/Mbc.E06-03-0251 |
0.616 |
|
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