| Year |
Citation |
Score |
| 2024 |
Li X, Zhou S, Tae HS, Wang S, Li T, Cai W, Jiang T, Adams DJ, Yu R. N-Terminal Capping of the αO-Conotoxin Analogue GeX-2 Improves the Serum Stability and Selectivity toward the Human α9α10 Nicotinic Acetylcholine Receptor. Journal of Medicinal Chemistry. PMID 39361522 DOI: 10.1021/acs.jmedchem.4c01758 |
0.411 |
|
| 2024 |
Tae HS, Ortells MO, Yousuf A, Xu SQ, Akk G, Adams DJ, Arias HR. Tabernanthalog and ibogainalog inhibit the α7 and α9α10 nicotinic acetylcholine receptors via different mechanisms and with higher potency than the GABA receptor and Ca2.2 channel. Biochemical Pharmacology. 116183. PMID 38580167 DOI: 10.1016/j.bcp.2024.116183 |
0.813 |
|
| 2024 |
Li T, Tae HS, Liang J, Zhang Z, Li X, Jiang T, Adams DJ, Yu R. Rational Design of Potent α-Conotoxin PeIA Analogues with Non-Natural Amino Acids for the Inhibition of Human α9α10 Nicotinic Acetylcholine Receptors. Marine Drugs. 22. PMID 38535451 DOI: 10.3390/md22030110 |
0.599 |
|
| 2024 |
Li X, Tae HS, Chen S, Yousuf A, Huang L, Zhang J, Jiang T, Adams DJ, Yu R. Dual Antagonism of α9α10 nAChR and GABA Receptor-Coupled Ca2.2 Channels by an Analgesic αO-Conotoxin Analogue. Journal of Medicinal Chemistry. PMID 38217860 DOI: 10.1021/acs.jmedchem.3c00979 |
0.804 |
|
| 2023 |
Tae HS, Ortells MO, Tekarli BJ, Manetti D, Romanelli MN, McIntosh JM, Adams DJ, Arias HR. DM506 (3-Methyl-1,2,3,4,5,6-hexahydroazepino[4,5-]indole fumarate), a Novel Derivative of Ibogamine, Inhibits α7 and α9α10 Nicotinic Acetylcholine Receptors by Different Allosteric Mechanisms. Acs Chemical Neuroscience. PMID 37386821 DOI: 10.1021/acschemneuro.3c00212 |
0.564 |
|
| 2023 |
Arias HR, Tae HS, Micheli L, Yousuf A, Manetti D, Romanelli MN, Ghelardini C, Adams DJ, Di Cesare Mannelli L. The Antinociceptive Activity of (E)-3-(thiophen-2-yl)-N-(p-tolyl)acrylamide in Mice Is Reduced by (E)-3-(furan-2-yl)-N-methyl-N-(p-tolyl)acrylamide Through Opposing Modulatory Mechanisms at the α7 Nicotinic Acetylcholine Receptor. Anesthesia and Analgesia. PMID 37058425 DOI: 10.1213/ANE.0000000000006461 |
0.765 |
|
| 2023 |
Tae HS, Adams DJ. Nicotinic acetylcholine receptor subtype expression, function, and pharmacology: Therapeutic potential of α-conotoxins. Pharmacological Research. 191: 106747. PMID 37001708 DOI: 10.1016/j.phrs.2023.106747 |
0.595 |
|
| 2023 |
Krishnarjuna B, Sunanda P, Seow J, Tae HS, Robinson SD, Belgi A, Robinson AJ, Safavi-Hemami H, Adams DJ, Norton RS. Characterisation of Elevenin-Vc1 from the Venom of : A Structural Analogue of α-Conotoxins. Marine Drugs. 21. PMID 36827123 DOI: 10.3390/md21020081 |
0.557 |
|
| 2023 |
Bye LJ, Finol-Urdaneta RK, Tae HS, Adams DJ. Nicotinic acetylcholine receptors: Key targets for attenuating neurodegenerative diseases. The International Journal of Biochemistry & Cell Biology. 157: 106387. PMID 36754161 DOI: 10.1016/j.biocel.2023.106387 |
0.703 |
|
| 2022 |
Hou X, Li C, Zhang R, Li Y, Li H, Zhang Y, Tae HS, Yu R, Che Q, Zhu T, Li D, Zhang G. Unusual Tetrahydropyridoindole-Containing Tetrapeptides with Human Nicotinic Acetylcholine Receptors Targeting Activity Discovered from Antarctica-Derived Psychrophilic sp. HDN17-933. Marine Drugs. 20. PMID 36286417 DOI: 10.3390/md20100593 |
0.307 |
|
| 2022 |
Liang J, Tae HS, Zhao Z, Li X, Zhang J, Chen S, Jiang T, Adams DJ, Yu R. Mechanism of Action and Structure-Activity Relationship of α-Conotoxin Mr1.1 at the Human α9α10 Nicotinic Acetylcholine Receptor. Journal of Medicinal Chemistry. PMID 36137181 DOI: 10.1021/acs.jmedchem.2c00494 |
0.585 |
|
| 2022 |
Ma Y, Cao Q, Yang M, Gao Y, Fu S, Du W, Adams DJ, Jiang T, Tae HS, Yu R. Single-Disulfide Conopeptide Czon1107, an Allosteric Antagonist of the Human α3β4 Nicotinic Acetylcholine Receptor. Marine Drugs. 20. PMID 36005500 DOI: 10.3390/md20080497 |
0.513 |
|
| 2022 |
Wilhelm P, Luna-Ramirez K, Chin YK, Dekan Z, Abraham N, Tae HS, Chow CY, Eagles DA, King GF, Lewis RJ, Adams DJ, Alewood PF. Cysteine-Rich α-Conotoxin SII Displays Novel Interactions at the Muscle Nicotinic Acetylcholine Receptor. Acs Chemical Neuroscience. PMID 35357806 DOI: 10.1021/acschemneuro.1c00857 |
0.814 |
|
| 2022 |
Finol-Urdaneta RK, Ziegman R, Dekan Z, McArthur JR, Heitmann S, Luna-Ramirez K, Tae HS, Mueller A, Starobova H, Chin YK, Wingerd JS, Undheim EAB, Cristofori-Armstrong B, Hill AP, Herzig V, et al. Multitarget nociceptor sensitization by a promiscuous peptide from the venom of the King Baboon spider. Proceedings of the National Academy of Sciences of the United States of America. 119. PMID 35074873 DOI: 10.1073/pnas.2110932119 |
0.751 |
|
| 2021 |
Zheng M, Tae HS, Xue L, Jiang T, Yu R. Mechanism of interactions between α-conotoxin RegIIA and carbohydrates at the human α3β4 nicotinic acetylcholine receptor. Marine Life Science & Technology. 4: 98-105. PMID 37073352 DOI: 10.1007/s42995-021-00108-9 |
0.396 |
|
| 2021 |
Bagdas D, Sevdar G, Gul Z, Younis R, Cavun S, Tae HS, Ortells MO, Arias HR, Gurun MS. (E)-3-furan-2-yl-N-phenylacrylamide (PAM-4) decreases nociception and emotional manifestations of neuropathic pain in mice by α7 nicotinic acetylcholine receptor potentiation. Neurological Research. 1-13. PMID 34281483 DOI: 10.1080/01616412.2021.1949684 |
0.422 |
|
| 2021 |
Tae HS, Gao B, Jin AH, Alewood PF, Adams DJ. Globular and ribbon isomers of Conus geographus α-conotoxins antagonize human nicotinic acetylcholine receptors. Biochemical Pharmacology. 114638. PMID 34062129 DOI: 10.1016/j.bcp.2021.114638 |
0.515 |
|
| 2021 |
Ning H, Huang B, Tae HS, Liu Z, Yu S, Li L, Zhang L, Adams DJ, Guo C, Dai Q. α-Conotoxin Bt1.8 from Conus betulinus selectively inhibits α6/α3β2β3 and ɑ3β2 nicotinic acetylcholine receptor subtypes. Journal of Neurochemistry. PMID 34008858 DOI: 10.1111/jnc.15434 |
0.618 |
|
| 2021 |
Belgi A, Burnley JV, MacRaild CA, Chhabra S, Elnahriry KA, Robinson SD, Gooding SG, Tae HS, Bartels P, Sadeghi M, Zhao FY, Wei H, Spanswick D, Adams DJ, Norton RS, et al. Alkyne-Bridged α-Conotoxin Vc1.1 Potently Reverses Mechanical Allodynia in Neuropathic Pain Models. Journal of Medicinal Chemistry. PMID 33724033 DOI: 10.1021/acs.jmedchem.0c02151 |
0.807 |
|
| 2021 |
Torres JP, Lin Z, Watkins M, Salcedo PF, Baskin RP, Elhabian S, Safavi-Hemami H, Taylor D, Tun J, Concepcion GP, Saguil N, Yanagihara AA, Fang Y, McArthur JR, Tae HS, et al. Small-molecule mimicry hunting strategy in the imperial cone snail, . Science Advances. 7. PMID 33712468 DOI: 10.1126/sciadv.abf2704 |
0.616 |
|
| 2020 |
Li X, Tae HS, Chu Y, Jiang T, Adams DJ, Yu R. Medicinal chemistry, pharmacology, and therapeutic potential of α-conotoxins antagonizing the α9α10 nicotinic acetylcholine receptor. Pharmacology & Therapeutics. 107792. PMID 33309557 DOI: 10.1016/j.pharmthera.2020.107792 |
0.59 |
|
| 2020 |
Arias HR, Ghelardini C, Lucarini E, Tae HS, Yousuf A, Marcovich I, Manetti D, Romanelli MN, Elgoyhen AB, Adams DJ, Di Cesare Mannelli L. ()-3-Furan-2-yl---tolyl-acrylamide and its Derivative DM489 Decrease Neuropathic Pain in Mice Predominantly by α7 Nicotinic Acetylcholine Receptor Potentiation. Acs Chemical Neuroscience. PMID 33073974 DOI: 10.1021/acschemneuro.0c00476 |
0.806 |
|
| 2020 |
Xu Q, Tae HS, Wang Z, Jiang T, Adams DJ, Yu R. Rational Design of α-Conotoxin RegIIA Analogues Specifically Inhibiting the Human α3β2 Nicotinic Acetylcholine Receptor through Computational Scanning. Acs Chemical Neuroscience. PMID 32649832 DOI: 10.1021/Acschemneuro.0C00293 |
0.605 |
|
| 2020 |
Arias HR, Tae HS, Micheli L, Yousuf A, Ghelardini C, Adams DJ, Di Cesare Mannelli L. Coronaridine congeners decrease neuropathic pain in mice and inhibit α9α10 nicotinic acetylcholine receptors and Ca2.2 channels. Neuropharmacology. 108194. PMID 32540451 DOI: 10.1016/J.Neuropharm.2020.108194 |
0.791 |
|
| 2020 |
Liang J, Tae HS, Xu X, Jiang T, Adams DJ, Yu R. Dimerization of α-conotoxins as a strategy to enhance the inhibition of the human α7 and α9α10 nicotinic acetylcholine receptors. Journal of Medicinal Chemistry. PMID 32101438 DOI: 10.1021/Acs.Jmedchem.9B01536 |
0.635 |
|
| 2019 |
Chandna R, Tae HS, Seymour VAL, Chathrath S, Adams DJ, Kini RM. Drysdalin, an antagonist of nicotinic acetylcholine receptors highlights the importance of functional rather than structural conservation of amino acid residues. Faseb Bioadvances. 1: 115-131. PMID 32123825 DOI: 10.1096/fba.1027 |
0.545 |
|
| 2019 |
Foo CS, Jobichen C, Hassan-Puttaswamy V, Dekan Z, Tae HS, Bertrand D, Adams DJ, Alewood PF, Sivaraman J, Nirthanan S, Kini RM. Fulditoxin, representing a new class of dimeric snake toxins, defines novel pharmacology at nicotinic acetylcholine receptors. British Journal of Pharmacology. PMID 31877243 DOI: 10.1111/Bph.14954 |
0.584 |
|
| 2019 |
Chu X, Tae HS, Xu Q, Jiang T, Adams DJ, Yu R. α-Conotoxin Vc1.1 Structure-Activity Relationship at the Human α9α10 Nicotinic Acetylcholine Receptor Investigated by Minimal Side Chain Replacement. Acs Chemical Neuroscience. PMID 31411453 DOI: 10.1021/Acschemneuro.9B00389 |
0.547 |
|
| 2019 |
Yu R, Tae HS, Xu Q, Craik DJ, Adams DJ, Jiang T, Kaas Q. Molecular dynamics simulations of dihydro-β-erythroidine bound to the human α4β2 nicotinic acetylcholine receptor. British Journal of Pharmacology. PMID 31062355 DOI: 10.1111/Bph.14698 |
0.5 |
|
| 2019 |
Xu S, Yang L, Kompella SN, Tae H, Zhang T, Lv A, Wang Y, Shao X, Ding J, Adams DJ, Wang C. Dissecting the nachr-inhibiting D-conotoxin GeXXA Toxicon. 158: S26. DOI: 10.1016/J.Toxicon.2018.10.095 |
0.745 |
|
| 2019 |
Yu R, Tae H, Tabassum N, Jiang T, Adams DJ. Interaction mechanism of α-conotoxins to the human α9α10 nAChR subtype Toxicon. 158: S24. DOI: 10.1016/J.Toxicon.2018.10.087 |
0.563 |
|
| 2018 |
Cai F, Xu N, Liu Z, Ding R, Yu S, Dong M, Wang S, Shen J, Tae HS, Adams DJ, Zhang X, Dai Q. α-Conotoxin Vc1.1 Variants Target N-type Calcium Channels via GABA Receptor Activation and Display Improved Analgesic Activity. Journal of Medicinal Chemistry. PMID 30358401 DOI: 10.1021/Acs.Jmedchem.8B01343 |
0.515 |
|
| 2018 |
Wu X, Tae HS, Huang YH, Adams DJ, Craik DJ, Kaas Q. Stoichiometry dependent inhibition of rat α3β4 nicotinic acetylcholine receptor by the ribbon isomer of α-conotoxin AuIB. Biochemical Pharmacology. PMID 30009767 DOI: 10.1016/J.Bcp.2018.07.007 |
0.585 |
|
| 2018 |
Sadeghi M, Carstens BB, Callaghan BP, Daniel JT, Tae HS, O'Donnell T, Castro J, Brierley SM, Adams DJ, Craik DJ, Clark RJ. Structure-activity studies reveal the molecular basis for GABAB-receptor mediated inhibition of high voltage-activated calcium channels by α-conotoxin Vc1.1. Acs Chemical Biology. PMID 29746088 DOI: 10.1021/Acschembio.8B00190 |
0.818 |
|
| 2018 |
Yu R, Tae HS, Tabassum N, Shi J, Jiang T, Adams DJ. Molecular determinants conferring the stoichiometric-dependent activity of α-conotoxins at the human α9α10 nicotinic acetylcholine receptor subtype. Journal of Medicinal Chemistry. PMID 29733583 DOI: 10.1021/Acs.Jmedchem.8B00115 |
0.643 |
|
| 2017 |
Tabassum N, Tae HS, Jia X, Kaas Q, Jiang T, Adams DJ, Yu R. Role of Cys-Cys Disulfide Bond on the Structure and Activity of α-Conotoxins at Human Neuronal Nicotinic Acetylcholine Receptors. Acs Omega. 2: 4621-4631. PMID 30023726 DOI: 10.1021/acsomega.7b00639 |
0.479 |
|
| 2017 |
Durek T, Shelukhina IV, Tae HS, Thongyoo P, Spirova EN, Kudryavtsev DS, Kasheverov IE, Faure G, Corringer PJ, Craik DJ, Adams DJ, Tsetlin VI. Interaction of Synthetic Human SLURP-1 with the Nicotinic Acetylcholine Receptors. Scientific Reports. 7: 16606. PMID 29192197 DOI: 10.1038/S41598-017-16809-0 |
0.631 |
|
| 2017 |
Hoggard MF, Rodriguez AM, Cano H, Clark E, Tae HS, Adams DJ, Godenschwege TA, Marí F. In vivo and in vitro testing of native α-conotoxins from the injected venom of Conus purpurascens. Neuropharmacology. PMID 28917942 DOI: 10.1016/J.Neuropharm.2017.09.020 |
0.624 |
|
| 2017 |
Tae HS, Smith KM, Phillips AM, Boyle KA, Li M, Forster IC, Hatch RJ, Richardson R, Hughes DI, Graham BA, Petrou S, Reid CA. Gabapentin Modulates HCN4 Channel Voltage-Dependence. Frontiers in Pharmacology. 8: 554. PMID 28871229 DOI: 10.3389/Fphar.2017.00554 |
0.343 |
|
| 2017 |
Wu X, Huang YH, Kaas Q, Harvey PJ, Wang CK, Tae HS, Adams DJ, Craik DJ. Backbone cyclization of analgesic conotoxin GeXIVA facilitates direct folding of the ribbon isomer. The Journal of Biological Chemistry. PMID 28851841 DOI: 10.1074/jbc.M117.808386 |
0.61 |
|
| 2017 |
Jiang S, Tae HS, Xu S, Shao X, Adams DJ, Wang C. Identification of a Novel O-Conotoxin Reveals an Unusual and Potent Inhibitor of the Human α9α10 Nicotinic Acetylcholine Receptor. Marine Drugs. 15. PMID 28598389 DOI: 10.3390/Md15060170 |
0.537 |
|
| 2017 |
Yang L, Tae HS, Fan Z, Shao X, Xu S, Zhao S, Adams DJ, Wang C. A Novel Lid-Covering Peptide Inhibitor of Nicotinic Acetylcholine Receptors Derived from αD-Conotoxin GeXXA. Marine Drugs. 15. PMID 28587231 DOI: 10.3390/Md15060164 |
0.547 |
|
| 2017 |
Cuny H, Yu R, Tae HS, Kompella SN, Adams DJ. α-Conotoxins active at α3-containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition. British Journal of Pharmacology. PMID 28477355 DOI: 10.1111/Bph.13852 |
0.805 |
|
| 2016 |
Cuny H, Kompella SN, Tae HS, Yu R, Adams DJ. Key Structural Determinants in the Agonist Binding Loops of Human β2 and β4 Nicotinic Acetylcholine Receptor Subunits Contribute to α3β4 Subtype Selectivity of α-Conotoxins. The Journal of Biological Chemistry. PMID 27646000 DOI: 10.1074/Jbc.M116.730804 |
0.779 |
|
| 2016 |
Carstens BB, Berecki G, Daniel JT, Lee HS, Jackson KA, Tae HS, Sadeghi M, Castro J, O'Donnell T, Deiteren A, Brierley SM, Craik DJ, Adams DJ, Clark RJ. Structure-Activity Studies of Cysteine-Rich α-Conotoxins that Inhibit High Voltage-Activated Calcium Channels via GABAB Receptor Activation Reveal a Minimal Functional Motif. Angewandte Chemie (International Ed. in English). PMID 26948522 DOI: 10.1002/Anie.201600297 |
0.777 |
|
| 2015 |
Wong LW, Tae HS, Cromer BA. Assembly, trafficking and function of α1β2γ2 GABAA receptors are regulated by N-terminal regions, in a subunit-specific manner. Journal of Neurochemistry. 134: 819-32. PMID 26016529 DOI: 10.1111/Jnc.13175 |
0.522 |
|
| 2015 |
Wan J, Huang JX, Vetter I, Mobli M, Lawson J, Tae HS, Abraham N, Paul B, Cooper MA, Adams DJ, Lewis RJ, Alewood PF. α-Conotoxin dendrimers have enhanced potency and selectivity for homomeric nicotinic acetylcholine receptors. Journal of the American Chemical Society. 137: 3209-12. PMID 25710197 DOI: 10.1021/Jacs.5B00244 |
0.623 |
|
| 2014 |
Wong LW, Tae HS, Cromer BA. Role of the ρ1 GABA(C) receptor N-terminus in assembly, trafficking and function. Acs Chemical Neuroscience. 5: 1266-77. PMID 25347026 DOI: 10.1021/Cn500220T |
0.479 |
|
| 2011 |
Tae HS, Cui Y, Karunasekara Y, Board PG, Dulhunty AF, Casarotto MG. Cyclization of the intrinsically disordered α1S dihydropyridine receptor II-III loop enhances secondary structure and in vitro function. The Journal of Biological Chemistry. 286: 22589-99. PMID 21525002 DOI: 10.1074/Jbc.M110.205476 |
0.366 |
|
| 2011 |
Tae H, Wei L, Willemse H, Mirza S, Gallant EM, Board PG, Dirksen RT, Casarotto MG, Dulhunty A. The elusive role of the SPRY2 domain in RyR1. Channels (Austin, Tex.). 5: 148-60. PMID 21239886 DOI: 10.4161/Chan.5.2.14407 |
0.31 |
|
| 2009 |
Tae H, Casarotto MG, Dulhunty AF. Ubiquitous SPRY domains and their role in the skeletal type ryanodine receptor. European Biophysics Journal. 39: 51-59. PMID 19399493 DOI: 10.1007/S00249-009-0455-8 |
0.318 |
|
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