| Year |
Citation |
Score |
| 2024 |
Brar KK, Hughes DT, Morris JL, Subramanian K, Krishna S, Gao F, Rieder LS, Uhrig S, Freeman J, Smith HL, Jukes-Jones R, Avezov E, Nunnari J, Prudent J, Butcher AJ, ... Mallucci GR, et al. PERK-ATAD3A interaction provides a subcellular safe haven for protein synthesis during ER stress. Science (New York, N.Y.). eadp7114. PMID 39116259 DOI: 10.1126/science.adp7114 |
0.366 |
|
| 2023 |
Albert-Gasco H, Smith HL, Alvarez-Castelao B, Swinden D, Halliday M, Janaki-Raman S, Butcher A, Mallucci GR. Trazodone rescues dysregulated synaptic and mitochondrial nascent proteomes in prion neurodegeneration. Brain : a Journal of Neurology. PMID 37703312 DOI: 10.1093/brain/awad313 |
0.311 |
|
| 2023 |
Lin JQ, Khuperkar D, Pavlou S, Makarchuk S, Patikas N, Lee FC, Zbiegly JM, Kang J, Field SF, Bailey DM, Freeman JL, Ule J, Metzakopian E, Ruepp MD, Mallucci GR. HNRNPH1 regulates the neuroprotective cold-shock protein RBM3 expression through poison exon exclusion. The Embo Journal. e113168. PMID 37248947 DOI: 10.15252/embj.2022113168 |
0.4 |
|
| 2021 |
Peretti D, Smith HL, Verity N, Humoud I, de Weerd L, Swinden DP, Hayes J, Mallucci GR. TrkB signaling regulates the cold-shock protein RBM3-mediated neuroprotection. Life Science Alliance. 4. PMID 33563652 DOI: 10.26508/lsa.202000884 |
0.422 |
|
| 2020 |
Hughes DT, Halliday M, Smith HL, Verity NC, Molloy C, Radford H, Butcher AJ, Mallucci GR. Targeting the kinase insert loop of PERK selectively modulates PERK signaling without systemic toxicity in mice. Science Signaling. 13. PMID 32788341 DOI: 10.1126/scisignal.abb4749 |
0.512 |
|
| 2020 |
Knight JRP, Garland G, Pöyry T, Mead E, Vlahov N, Sfakianos A, Grosso S, De-Lima-Hedayioglu F, Mallucci GR, von der Haar T, Smales CM, Sansom OJ, Willis AE. Control of translation elongation in health and disease. Disease Models & Mechanisms. 13. PMID 32298235 DOI: 10.1242/dmm.043208 |
0.425 |
|
| 2020 |
Smith HL, Freeman OJ, Butcher AJ, Holmqvist S, Humoud I, Schätzl T, Hughes DT, Verity NC, Swinden DP, Hayes J, de Weerd L, Rowitch DH, Franklin RJM, Mallucci GR. Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration. Neuron. PMID 31924446 DOI: 10.1016/J.Neuron.2019.12.014 |
0.338 |
|
| 2019 |
Gonzalez-Teuber V, Albert-Gasco H, Auyeung VC, Papa FR, Mallucci GR, Hetz C. Small Molecules to Improve ER Proteostasis in Disease. Trends in Pharmacological Sciences. PMID 31377018 DOI: 10.1016/j.tips.2019.07.003 |
0.321 |
|
| 2018 |
Boland B, Yu WH, Corti O, Mollereau B, Henriques A, Bezard E, Pastores GM, Rubinsztein DC, Nixon RA, Duchen MR, Mallucci GR, Kroemer G, Levine B, Eskelinen EL, Mochel F, et al. Promoting the clearance of neurotoxic proteins in neurodegenerative disorders of ageing. Nature Reviews. Drug Discovery. PMID 30116051 DOI: 10.1038/Nrd.2018.109 |
0.301 |
|
| 2018 |
Robinson SW, Bourgognon JM, Spiers JG, Breda C, Campesan S, Butcher A, Mallucci GR, Dinsdale D, Morone N, Mistry R, Smith TM, Guerra-Martin M, Challiss RAJ, Giorgini F, Steinert JR. Nitric oxide-mediated posttranslational modifications control neurotransmitter release by modulating complexin farnesylation and enhancing its clamping ability. Plos Biology. 16: e2003611. PMID 29630591 DOI: 10.1371/Journal.Pbio.2003611 |
0.375 |
|
| 2018 |
Hughes D, Mallucci GR. The unfolded protein response in neurodegenerative disorders - therapeutic modulation of the PERK pathway. The Febs Journal. PMID 29476642 DOI: 10.1111/febs.14422 |
0.551 |
|
| 2017 |
Halliday M, Hughes D, Mallucci G. Fine tuning PERK signaling for neuroprotection. Journal of Neurochemistry. PMID 28643372 DOI: 10.1111/jnc.14112 |
0.482 |
|
| 2017 |
Bastide A, Peretti D, Knight JR, Grosso S, Spriggs RV, Pichon X, Sbarrato T, Roobol A, Roobol J, Vito D, Bushell M, von der Haar T, Smales CM, Mallucci GR, Willis AE. RTN3 Is a Novel Cold-Induced Protein and Mediates Neuroprotective Effects of RBM3. Current Biology : Cb. PMID 28238655 DOI: 10.1016/j.cub.2017.01.047 |
0.384 |
|
| 2016 |
Celardo I, Costa AC, Lehmann S, Jones C, Wood N, Mencacci NE, Mallucci GR, Loh SH, Martins LM. Mitofusin-mediated ER stress triggers neurodegeneration in pink1/parkin models of Parkinson's disease. Cell Death & Disease. 7: e2271. PMID 27336715 DOI: 10.1038/cddis.2016.173 |
0.371 |
|
| 2016 |
Smith HL, Mallucci GR. The unfolded protein response: mechanisms and therapy of neurodegeneration. Brain : a Journal of Neurology. PMID 27190028 DOI: 10.1093/brain/aww101 |
0.405 |
|
| 2015 |
Halliday M, Radford H, Sekine Y, Moreno J, Verity N, le Quesne J, Ortori CA, Barrett DA, Fromont C, Fischer PM, Harding HP, Ron D, Mallucci GR. Partial restoration of protein synthesis rates by the small molecule ISRIB prevents neurodegeneration without pancreatic toxicity. Cell Death & Disease. 6: e1672. PMID 25741597 DOI: 10.1038/Cddis.2015.49 |
0.392 |
|
| 2013 |
Mallucci G. Spreading proteins in neurodegeneration: where do they take us? Brain : a Journal of Neurology. 136: 994-5. PMID 23518708 DOI: 10.1093/brain/awt072 |
0.331 |
|
| 2012 |
Moreno JA, Radford H, Peretti D, Steinert JR, Verity N, Martin MG, Halliday M, Morgan J, Dinsdale D, Ortori CA, Barrett DA, Tsaytler P, Bertolotti A, Willis AE, Bushell M, ... Mallucci GR, et al. Sustained translational repression by eIF2α-P mediates prion neurodegeneration. Nature. 485: 507-11. PMID 22622579 DOI: 10.1038/Nature11058 |
0.382 |
|
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