Robert W. Nickells - Publications

Affiliations: 
Ophthalmology University of Wisconsin, Madison, Madison, WI 

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Mac Nair CE, Schlamp CL, Montgomery AD, Shestopalov VI, Nickells RW. Retinal glial responses to optic nerve crush are attenuated in Bax-deficient mice and modulated by purinergic signaling pathways. Journal of Neuroinflammation. 13: 93. PMID 27126275 DOI: 10.1186/s12974-016-0558-y  0.88
2015 Schmitt HM, Schlamp CL, Nickells RW. Role of HDACs in optic nerve damage-induced nuclear atrophy of retinal ganglion cells. Neuroscience Letters. PMID 26733303 DOI: 10.1016/j.neulet.2015.12.012  0.88
2015 Nickells RW. The Long-Term Effects on the Retina Damaged by Optic Nerve Axotomy. Investigative Ophthalmology & Visual Science. 56: 6113. PMID 26393670 DOI: 10.1167/iovs.15-17997  0.88
2015 Nickells RW, Pelzel HR. Tools and resources for analyzing gene expression changes in glaucomatous neurodegeneration. Experimental Eye Research. PMID 25999234 DOI: 10.1016/j.exer.2015.05.009  0.88
2015 Mac Nair CE, Nickells RW. Neuroinflammation in Glaucoma and Optic Nerve Damage Progress in Molecular Biology and Translational Science. DOI: 10.1016/bs.pmbts.2015.06.010  0.88
2014 Schmitt HM, Pelzel HR, Schlamp CL, Nickells RW. Histone deacetylase 3 (HDAC3) plays an important role in retinal ganglion cell death after acute optic nerve injury. Molecular Neurodegeneration. 9: 39. PMID 25261965 DOI: 10.1186/1750-1326-9-39  0.88
2014 Dietz JA, Maes ME, Huang S, Yandell BS, Schlamp CL, Montgomery AD, Allingham RR, Hauser MA, Nickells RW. Spink2 modulates apoptotic susceptibility and is a candidate gene in the Rgcs1 QTL that affects retinal ganglion cell death after optic nerve damage. Plos One. 9: e93564. PMID 24699552 DOI: 10.1371/journal.pone.0093564  0.88
2013 Schlamp CL, Montgomery AD, Mac Nair CE, Schuart C, Willmer DJ, Nickells RW. Evaluation of the percentage of ganglion cells in the ganglion cell layer of the rodent retina. Molecular Vision. 19: 1387-96. PMID 23825918  0.88
2013 Welsbie DS, Yang Z, Ge Y, Mitchell KL, Zhou X, Martin SE, Berlinicke CA, Hackler L, Fuller J, Fu J, Cao LH, Han B, Auld D, Xue T, Hirai S, ... ... Nickells RW, et al. Functional genomic screening identifies dual leucine zipper kinase as a key mediator of retinal ganglion cell death. Proceedings of the National Academy of Sciences of the United States of America. 110: 4045-50. PMID 23431148 DOI: 10.1073/pnas.1211284110  0.88
2013 Janssen KT, Mac Nair CE, Dietz JA, Schlamp CL, Nickells RW. Nuclear atrophy of retinal ganglion cells precedes the bax-dependent stage of apoptosis. Investigative Ophthalmology & Visual Science. 54: 1805-15. PMID 23422829 DOI: 10.1167/iovs.11-9310  0.88
2012 Toops KA, Hagemann TL, Messing A, Nickells RW. The effect of glial fibrillary acidic protein expression on neurite outgrowth from retinal explants in a permissive environment. Bmc Research Notes. 5: 693. PMID 23259929 DOI: 10.1186/1756-0500-5-693  0.88
2012 Nickells RW. The cell and molecular biology of glaucoma: mechanisms of retinal ganglion cell death. Investigative Ophthalmology & Visual Science. 53: 2476-81. PMID 22562845 DOI: 10.1167/iovs.12-9483h  0.88
2012 Nickells RW, Howell GR, Soto I, John SW. Under pressure: cellular and molecular responses during glaucoma, a common neurodegeneration with axonopathy. Annual Review of Neuroscience. 35: 153-79. PMID 22524788 DOI: 10.1146/annurev.neuro.051508.135728  0.88
2012 Nickells RW, Merbs SL. The potential role of epigenetics in ocular diseases. Archives of Ophthalmology (Chicago, Ill. : 1960). 130: 508-9. PMID 22491920 DOI: 10.1001/archopthalmol.2011.1423  0.88
2012 Toops KA, Berlinicke C, Zack DJ, Nickells RW. Hydrocortisone stimulates neurite outgrowth from mouse retinal explants by modulating macroglial activity. Investigative Ophthalmology & Visual Science. 53: 2046-61. PMID 22395888 DOI: 10.1167/iovs.11-8646  0.88
2012 Pelzel HR, Schlamp CL, Waclawski M, Shaw MK, Nickells RW. Silencing of Fem1cR3 gene expression in the DBA/2J mouse precedes retinal ganglion cell death and is associated with histone deacetylase activity. Investigative Ophthalmology & Visual Science. 53: 1428-35. PMID 22297488 DOI: 10.1167/iovs.11-8872  0.88
2011 Pelzel HR, Nickells RW. A role for epigenetic changes in the development of retinal neurodegenerative conditions. Journal of Ocular Biology, Diseases, and Informatics. 4: 104-10. PMID 23515137 DOI: 10.1007/s12177-012-9079-9  0.88
2011 Mavlyutov TA, Nickells RW, Guo LW. Accelerated retinal ganglion cell death in mice deficient in the Sigma-1 receptor. Molecular Vision. 17: 1034-43. PMID 21541278  0.88
2010 Semaan SJ, Nickells RW. The apoptotic response in HCT116BAX-/- cancer cells becomes rapidly saturated with increasing expression of a GFP-BAX fusion protein. Bmc Cancer. 10: 554. PMID 20942963 DOI: 10.1186/1471-2407-10-554  0.88
2010 Pelzel HR, Schlamp CL, Nickells RW. Histone H4 deacetylation plays a critical role in early gene silencing during neuronal apoptosis. Bmc Neuroscience. 11: 62. PMID 20504333 DOI: 10.1186/1471-2202-11-62  0.88
2010 Semaan SJ, Li Y, Nickells RW. A single nucleotide polymorphism in the Bax gene promoter affects transcription and influences retinal ganglion cell death. Asn Neuro. 2: e00032. PMID 20360947 DOI: 10.1042/AN20100003  0.88
2010 Nickells RW. Variations in the rheostat model of apoptosis: what studies of retinal ganglion cell death tell us about the functions of the Bcl2 family proteins. Experimental Eye Research. 91: 2-8. PMID 20230818 DOI: 10.1016/j.exer.2010.03.004  0.88
2009 Cordeiro MF, Nickells R, Drexler W, Borrás T, Ritch R. High-resolution ocular imaging: Combining advanced optics and microtechnology Ophthalmic Surgery Lasers and Imaging. 40: 480-488. PMID 19772272 DOI: 10.3928/15428877-20090901-07  0.88
2009 Tezel G, Ben-Hur T, Gibson GE, Stevens B, Streit WJ, Wekerle H, Bhattacharya SK, Borras T, Burgoyne CF, Caspi RR, Chauhan BC, Clark AF, Crowston J, Danias J, Dick AD, ... ... Nickells RW, et al. The role of glia, mitochondria, and the immune system in glaucoma Investigative Ophthalmology and Visual Science. 50: 1001-1012. PMID 19244206 DOI: 10.1167/iovs.08-2717  0.88
2009 McKinnon SJ, Schlamp CL, Nickells RW. Mouse models of retinal ganglion cell death and glaucoma. Experimental Eye Research. 88: 816-24. PMID 19105954 DOI: 10.1016/j.exer.2008.12.002  0.88
2008 Nickells RW, Semaan SJ, Schlamp CL. Involvement of the Bcl2 gene family in the signaling and control of retinal ganglion cell death. Progress in Brain Research. 173: 423-35. PMID 18929125 DOI: 10.1016/S0079-6123(08)01129-1  0.88
2008 Dietz JA, Li Y, Chung LM, Yandell BS, Schlamp CL, Nickells RW. Rgcs1, a dominant QTL that affects retinal ganglion cell death after optic nerve crush in mice. Bmc Neuroscience. 9: 74. PMID 18671875 DOI: 10.1186/1471-2202-9-74  0.88
2007 Nickells RW. Ganglion cell death in glaucoma: from mice to men. Veterinary Ophthalmology. 10: 88-94. PMID 17973839 DOI: 10.1111/j.1463-5224.2007.00564.x  0.88
2007 Nickells RW. From ocular hypertension to ganglion cell death: a theoretical sequence of events leading to glaucoma. Canadian Journal of Ophthalmology. Journal Canadien D'Ophtalmologie. 42: 278-87. PMID 17392853 DOI: 10.3129/can j ophthalmol.i07-036  0.88
2007 Li Y, Semaan SJ, Schlamp CL, Nickells RW. Dominant inheritance of retinal ganglion cell resistance to optic nerve crush in mice. Bmc Neuroscience. 8: 19. PMID 17338819 DOI: 10.1186/1471-2202-8-19  0.88
2007 Nickells RW, Schlamp CL, Li Y, Kaufman PL, Heatley G, Peterson JC, Faha B, Ver Hoeve JN. Surgical lowering of elevated intraocular pressure in monkeys prevents progression of glaucomatous disease. Experimental Eye Research. 84: 729-36. PMID 17291496 DOI: 10.1016/j.exer.2006.12.011  0.88
2006 Pelzel HR, Schlamp CL, Poulsen GL, Ver Hoeve JA, Nork TM, Nickells RW. Decrease of cone opsin mRNA in experimental ocular hypertension. Molecular Vision. 12: 1272-82. PMID 17110910  0.88
2006 Schlamp CL, Li Y, Dietz JA, Janssen KT, Nickells RW. Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric. Bmc Neuroscience. 7: 66. PMID 17018142 DOI: 10.1186/1471-2202-7-66  0.88
2005 Libby RT, Li Y, Savinova OV, Barter J, Smith RS, Nickells RW, John SW. Susceptibility to neurodegeneration in a glaucoma is modified by Bax gene dosage. Plos Genetics. 1: 17-26. PMID 16103918 DOI: 10.1371/journal.pgen.0010004  0.88
2004 Farkas RH, Chowers I, Hackam AS, Kageyama M, Nickells RW, Otteson DC, Duh EJ, Wang C, Valenta DF, Gunatilaka TL, Pease ME, Quigley HA, Zack DJ. Increased expression of iron-regulating genes in monkey and human glaucoma. Investigative Ophthalmology & Visual Science. 45: 1410-7. PMID 15111596 DOI: 10.1167/iovs.03-0872  0.88
2004 Schlamp CL, Thliveris AT, Li Y, Kohl LP, Knop C, Dietz JA, Larsen IV, Imesch P, Pinto LH, Nickells RW. Insertion of the beta Geo promoter trap into the Fem1c gene of ROSA3 mice. Molecular and Cellular Biology. 24: 3794-803. PMID 15082774 DOI: 10.1128/MCB.24.9.3794-3803.2004  0.88
2004 Nickells RW. The molecular biology of retinal ganglion cell death: caveats and controversies. Brain Research Bulletin. 62: 439-46. PMID 15036555 DOI: 10.1016/j.brainresbull.2003.07.007  0.88
2003 Audo I, Darjatmoko SR, Schlamp CL, Lokken JM, Lindstrom MJ, Albert DM, Nickells RW. Vitamin D analogues increase p53, p21, and apoptosis in a xenograft model of human retinoblastoma. Investigative Ophthalmology & Visual Science. 44: 4192-9. PMID 14507860 DOI: 10.1167/iovs.02-1198  0.88
2002 Li Y, Schlamp CL, Poulsen GL, Jackson MW, Griep AE, Nickells RW. p53 regulates apoptotic retinal ganglion cell death induced by N-methyl-D-aspartate. Molecular Vision. 8: 341-50. PMID 12355059  0.88
2002 Albert DM, Nickells RW, Gamm DM, Zimbric ML, Schlamp CL, Lindstrom MJ, Audo I. Vitamin D analogs, a new treatment for retinoblastoma: The first Ellsworth Lecture. Ophthalmic Genetics. 23: 137-56. PMID 12324873 DOI: 10.1076/opge.23.3.137.7883  0.88
2002 Borrás T, Brandt CR, Nickells R, Ritch R. Gene therapy for glaucoma: treating a multifaceted, chronic disease. Investigative Ophthalmology & Visual Science. 43: 2513-8. PMID 12147578  0.88
2002 Perkins TW, Faha B, Ni M, Kiland JA, Poulsen GL, Antelman D, Atencio I, Shinoda J, Sinha D, Brumback L, Maneval D, Kaufman PL, Nickells RW. Adenovirus-mediated gene therapy using human p21WAF-1/Cip-1 to prevent wound healing in a rabbit model of glaucoma filtration surgery. Archives of Ophthalmology (Chicago, Ill. : 1960). 120: 941-9. PMID 12096965  0.88
2001 Quigley HA, Nork TM, Poulsen GL, Nickells RW, Ver Hoeve JN, Cho NC, Levin LA, Lucarelli MJ. Selective citation of evidence regarding photoreceptor loss in glaucoma [1] Archives of Ophthalmology. 119: 1390-1391. PMID 11545654  0.88
2001 Schlamp CL, Johnson EC, Li Y, Morrison JC, Nickells RW. Changes in Thy1 gene expression associated with damaged retinal ganglion cells. Molecular Vision. 7: 192-201. PMID 11509915  0.88
2000 Nork TM, Poulsen GL, Nickells RW, Ver Hoeve JN, Cho NC, Levin LA, Lucarelli MJ. Protection of ganglion cells in experimental glaucoma by retinal laser photocoagulation. Archives of Ophthalmology (Chicago, Ill. : 1960). 118: 1242-50. PMID 10980770  0.88
2000 Li Y, Schlamp CL, Poulsen KP, Nickells RW. Bax-dependent and independent pathways of retinal ganglion cell death induced by different damaging stimuli. Experimental Eye Research. 71: 209-13. PMID 10930325 DOI: 10.1006/exer.2000.0873  0.88
2000 Sarkar S, Jülicher KP, Burger MS, Della Valle V, Larsen CJ, Yeager TR, Grossman TB, Nickells RW, Protzel C, Jarrard DF, Reznikoff CA. Different combinations of genetic/epigenetic alterations inactivate the p53 and pRb pathways in invasive human bladder cancers. Cancer Research. 60: 3862-71. PMID 10919661  0.88
2000 Nork TM, Ver Hoeve JN, Poulsen GL, Nickells RW, Davis MD, Weber AJ, Vaegan, Sarks SH, Lemley HL, Millecchia LL. Swelling and loss of photoreceptors in chronic human and experimental glaucomas. Archives of Ophthalmology (Chicago, Ill. : 1960). 118: 235-45. PMID 10676789  0.88
1999 Nickells RW. Apoptosis of retinal ganglion cells in glaucoma: an update of the molecular pathways involved in cell death. Survey of Ophthalmology. 43: S151-61. PMID 10416758 DOI: 10.1016/S0039-6257(99)00029-6  0.88
1999 Li Y, Schlamp CL, Nickells RW. Experimental induction of retinal ganglion cell death in adult mice. Investigative Ophthalmology & Visual Science. 40: 1004-8. PMID 10102300  0.88
1998 Perez-Mediavilla LA, Chew C, Campochiaro PA, Nickells RW, Notario V, Zack DJ, Becerra SP. Sequence and expression analysis of bovine pigment epithelium-derived factor. Biochimica Et Biophysica Acta. 1398: 203-14. PMID 9689919 DOI: 10.1016/S0167-4781(98)00055-4  0.88
1997 Levin LA, Schlamp CL, Spieldoch RL, Geszvain KM, Nickells RW. Identification of the bcl-2 family of genes in the rat retina. Investigative Ophthalmology & Visual Science. 38: 2545-53. PMID 9375574  0.88
1997 Schlamp CL, Poulsen GL, Nork TM, Nickells RW. Nuclear exclusion of wild-type p53 in immortalized human retinoblastoma cells. Journal of the National Cancer Institute. 89: 1530-6. PMID 9337350  0.88
1997 Nork TM, Poulsen GL, Millecchia LL, Jantz RG, Nickells RW. p53 regulates apoptosis in human retinoblastoma. Archives of Ophthalmology (Chicago, Ill. : 1960). 115: 213-9. PMID 9046256  0.88
1997 Nork TM, Ver Hoeve JN, Poulsen GL, Nickells RW, Weber AJ, Sarks SH, Lemley H, Millecchia LL. Photoreceptor swelling and loss in chronic human and experimental glaucomas Investigative Ophthalmology and Visual Science. 38: S163.  0.88
1997 Li Y, Schlamp CL, Levin LA, Nickells RW. Experimentai. stimulation of gangeion cell death in mice: A model for analyzing genes that regulate rcic apoptosis Investigative Ophthalmology and Visual Science. 38: S163.  0.88
1997 Nickells RW, Schlamp CL, Poulsen G, Nork TM. The role of p53 in retinoblastoma: The difference between life, death, and immortalization Investigative Ophthalmology and Visual Science. 38: S486.  0.88
1996 Nickells RW, Zack DJ. Apoptosis in ocular disease: a molecular overview. Ophthalmic Genetics. 17: 145-65. PMID 9010866 DOI: 10.3109/13816819609057889  0.88
1996 Nickells RW. Retinal ganglion cell death in glaucoma: the how, the why, and the maybe. Journal of Glaucoma. 5: 345-56. PMID 8897235 DOI: 10.1016/B978-0-7020-2983-7.00027-9  0.88
1996 Schlamp CL, Nickells RW. Light and dark cause a shift in the spatial expression of a neuropeptide-processing enzyme in the rat retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 2164-71. PMID 8601797  0.88
1996 Nork TM, Poulsen GL, Nickells RW. Immunocytochemical evidence for up regulation of nitric oxide synthase and p53 in ganglion cells in primary open angle glaucoma Investigative Ophthalmology and Visual Science. 37: S408.  0.88
1996 Levin LA, Spieldoch RL, Geszvain KM, Schlamp CL, Nickells RW. Expression of bcl-2 family gene(S) after retinal ganglion cell axotomy Investigative Ophthalmology and Visual Science. 37: S1121.  0.88
1996 Nickells RW, Schlamp CL, Jantz RG, Poulsen G, Norlz TM. Apoptosis or transformation: Alternative cell fate in human retinoblastoma linked to p53 Investigative Ophthalmology and Visual Science. 37: S331.  0.88
1995 Nickells RW, Burgoyne CF, Quigley HA, Zack DJ. Cloning and characterization of rod opsin cDNA from the Old World monkey, Macaca fascicularis. Investigative Ophthalmology & Visual Science. 36: 72-82. PMID 7822161  0.88
1995 Quigley HA, Nickells RW, Kerrigan LA, Pease ME, Thibault DJ, Zack DJ. Retinal ganglion cell death in experimental glaucoma and after axotomy occurs by apoptosis. Investigative Ophthalmology & Visual Science. 36: 774-86. PMID 7706025  0.88
1993 Nickells RW, Schlamp CL, Newton AC, Williams DS. Gene expression of the neuropeptide-processing enzyme carboxypeptidase E in rat photoreceptor cells. Journal of Neurochemistry. 61: 1891-900. PMID 7693871  0.88
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