Karl J. Wahlin, Ph.D. - Publications

Affiliations: 
2002-2009 Neuroscience Johns Hopkins University School of Medicine, Baltimore, MD, United States 
 2009-2015 Ophthalmology Johns Hopkins University School of Medicine, Baltimore, MD, United States 

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Do JL, Pedroarena-Leal N, Louie M, Avila Garcia P, Alnihmy A, Patel A, Weinreb RN, Wahlin KJ, La Torre Vila A, Welsbie DS. Mechanical Disruption of the Inner Limiting Membrane In Vivo Enhances Targeting to the Inner Retina. Investigative Ophthalmology & Visual Science. 64: 25. PMID 38117244 DOI: 10.1167/iovs.64.15.25  0.71
2023 Agarwal D, Dash N, Mazo KW, Chopra M, Avila MP, Patel A, Wong RM, Jia C, Do H, Cheng J, Chiang C, Jurlina SL, Roshan M, Perry MW, Rho JM, ... ... Wahlin KJ, et al. Human retinal ganglion cell neurons generated by synchronous BMP inhibition and transcription factor mediated reprogramming. Npj Regenerative Medicine. 8: 55. PMID 37773257 DOI: 10.1038/s41536-023-00327-x  0.75
2023 Sripathi SR, Hu MW, Turaga RC, Mikeasky R, Satyanarayana G, Cheng J, Duan Y, Maruotti J, Wahlin KJ, Berlinicke CA, Qian J, Esumi N, Zack DJ. IKKβ Inhibition Attenuates Epithelial Mesenchymal Transition of Human Stem Cell-Derived Retinal Pigment Epithelium. Cells. 12. PMID 37190063 DOI: 10.3390/cells12081155  0.714
2023 Morales Pantoja IE, Smirnova L, Muotri AR, Wahlin KJ, Kahn J, Boyd JL, Gracias DH, Harris TD, Cohen-Karni T, Caffo BS, Szalay AS, Han F, Zack DJ, Etienne-Cummings R, Akwaboah A, et al. First Organoid Intelligence (OI) workshop to form an OI community. Frontiers in Artificial Intelligence. 6: 1116870. PMID 36925616 DOI: 10.3389/frai.2023.1116870  0.448
2022 Maiti G, Monteiro de Barros MR, Hu N, Dolgalev I, Roshan M, Foster JW, Tsirigos A, Wahlin KJ, Chakravarti S. Single cell RNA-seq of human cornea organoids identifies cell fates of a developing immature cornea. Pnas Nexus. 1: pgac246. PMID 36712326 DOI: 10.1093/pnasnexus/pgac246  0.332
2022 Agarwal D, Do H, Mazo KW, Chopra M, Wahlin KJ. Restoring vision and rebuilding the retina by Müller glial cell reprogramming. Stem Cell Research. 66: 103006. PMID 36563542 DOI: 10.1016/j.scr.2022.103006  0.406
2022 Agarwal D, Kuhns R, Dimitriou CN, Barlow E, Wahlin KJ, Enke RA. Bulk RNA sequencing analysis of developing human induced pluripotent cell-derived retinal organoids. Scientific Data. 9: 759. PMID 36494376 DOI: 10.1038/s41597-022-01853-x  0.409
2022 Jones MK, Agarwal D, Mazo KW, Chopra M, Jurlina SL, Dash N, Xu Q, Ogata AR, Chow M, Hill AD, Kambli NK, Xu G, Sasik R, Birmingham A, Fisch KM, ... ... Wahlin KJ, et al. Chromatin Accessibility and Transcriptional Differences in Human Stem Cell-Derived Early-Stage Retinal Organoids. Cells. 11. PMID 36359808 DOI: 10.3390/cells11213412  0.448
2022 Gage E, Agarwal D, Chenault C, Washington-Brown K, Szvetecz S, Jahan N, Wang Z, Jones MK, Zack DJ, Enke RA, Wahlin KJ. Temporal and Isoform-Specific Expression of Is Evolutionarily Conserved Between the Developing Chick and Human Retina. Frontiers in Molecular Neuroscience. 14: 773356. PMID 35095414 DOI: 10.3389/fnmol.2021.773356  0.635
2021 Wahlin KJ, Cheng J, Jurlina SL, Jones MK, Dash NR, Ogata A, Kibria N, Ray S, Eldred KC, Kim C, Heng JS, Phillips J, Johnston RJ, Gamm DM, Berlinicke C, et al. CRISPR Generated SIX6 and POU4F2 Reporters Allow Identification of Brain and Optic Transcriptional Differences in Human PSC-Derived Organoids. Frontiers in Cell and Developmental Biology. 9: 764725. PMID 34869356 DOI: 10.3389/fcell.2021.764725  0.6
2021 Sripathi SR, Hu MW, Turaga RC, Mertz J, Liu MM, Wan J, Maruotti J, Wahlin KJ, Berlinicke CA, Qian J, Zack DJ. Epithelial to mesenchymal transition (EMT) of human stem cell-derived retinal pigment epithelium shares commonalities with malignancy-associated EMT: a proteomic analysis. Molecular & Cellular Proteomics : McP. 100131. PMID 34455105 DOI: 10.1016/j.mcpro.2021.100131  0.575
2021 Sripathi SR, Hu MW, Liu MM, Wan J, Cheng J, Duan Y, Mertz JL, Wahlin KJ, Maruotti J, Berlinicke CA, Qian J, Zack DJ. Transcriptome Landscape of Epithelial to Mesenchymal Transition of Human Stem Cell-Derived RPE. Investigative Ophthalmology & Visual Science. 62: 1. PMID 33792620 DOI: 10.1167/iovs.62.4.1  0.557
2020 Patel AK, Broyer RM, Lee CD, Lu T, Louie MJ, La Torre A, Al-Ali H, Vu MT, Mitchell KL, Wahlin KJ, Berlinicke CA, Jaskula-Ranga V, Hu Y, Duan X, Vilar S, et al. Inhibition of GCK-IV kinases dissociates cell death and axon regeneration in CNS neurons. Proceedings of the National Academy of Sciences of the United States of America. PMID 33318207 DOI: 10.1073/pnas.2004683117  0.717
2020 Biswas P, Borooah S, Matsui H, Voronchikhina M, Zhou J, Raghavendra PB, Riazuddin SA, Wahlin K, Frazer KA, Ayyagari R. Detection and validation of novel mutations in MERTK in a simplex case of retinal degeneration using WGS and hiPSC-RPEs model. Human Mutation. PMID 33252167 DOI: 10.1002/humu.24146  0.335
2020 Barnett BP, Wahlin K, Krawczyk M, Spencer D, Welsbie D, Afshari N, Chao D. Potential of Ocular Transmission of SARS-CoV-2: A Review. Vision (Basel, Switzerland). 4. PMID 32883010 DOI: 10.3390/vision4030040  0.651
2020 Foster JW, Wahlin KJ, Chakravarti S. A Guide to the Development of Human CorneaOrganoids from Induced Pluripotent Stem Cells in Culture. Methods in Molecular Biology (Clifton, N.J.). 2145: 51-58. PMID 32542600 DOI: 10.1007/978-1-0716-0599-8_5  0.399
2019 Mishra B, Wilson DR, Sripathi SR, Suprenant MP, Rui Y, Wahlin KJ, Berlinicke CA, Green JJ, Zack DJ. A combinatorial library of biodegradable polyesters enables non-viral gene delivery to post-mitotic human stem cell-derived polarized RPE monolayers. Regenerative Engineering and Translational Medicine. 6: 273-285. PMID 33732871 DOI: 10.1007/s40883-019-00118-1  0.541
2019 Huang KC, Wang ML, Chen SJ, Kuo JC, Wang WJ, Nhi Nguyen PN, Wahlin KJ, Lu JF, Tran AA, Shi M, Chien Y, Yarmishyn AA, Tsai PH, Yang TC, Jane WN, et al. Morphological and Molecular Defects in Human Three-Dimensional Retinal Organoid Model of X-Linked Juvenile Retinoschisis. Stem Cell Reports. PMID 31668851 DOI: 10.1016/J.Stemcr.2019.09.010  0.409
2018 Eldred KC, Hadyniak SE, Hussey KA, Brenerman B, Zhang PW, Chamling X, Sluch VM, Welsbie DS, Hattar S, Taylor J, Wahlin K, Zack DJ, Johnston RJ. Thyroid hormone signaling specifies cone subtypes in human retinal organoids. Science (New York, N.Y.). 362. PMID 30309916 DOI: 10.1126/Science.Aau6348  0.732
2017 Aleen Remez L, Onishi A, Menuchin-Lasowski Y, Biran A, Blackshaw S, Wahlin KJ, Zack DJ, Ashery-Padan R. Pax6 is essential for the generation of late-born retinal neurons and for inhibition of photoreceptor-fate during late stages of retinogenesis. Developmental Biology. PMID 28993200 DOI: 10.1016/J.Ydbio.2017.09.030  0.527
2017 Vergara MN, Flores-Bellver M, Aparicio-Domingo S, McNally M, Wahlin KJ, Saxena MT, Mumm JS, Canto-Soler MV. Enabling quantitative screening in retinal organoids: 3D automated reporter quantification technology (3D-ARQ). Development (Cambridge, England). PMID 28870990 DOI: 10.1242/Dev.146290  0.388
2017 Wilson DR, Routkevitch D, Rui Y, Mosenia A, Wahlin KJ, Quinones-Hinojosa A, Zack DJ, Green JJ. A Triple-Fluorophore-Labeled Nucleic Acid pH Nanosensor to Investigate Non-viral Gene Delivery. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28479046 DOI: 10.1016/J.Ymthe.2017.04.008  0.498
2017 Wahlin KJ, Maruotti JA, Sripathi SR, Ball J, Angueyra JM, Kim C, Grebe R, Li W, Jones BW, Zack DJ. Photoreceptor Outer Segment-like Structures in Long-Term 3D Retinas from Human Pluripotent Stem Cells. Scientific Reports. 7: 766. PMID 28396597 DOI: 10.1038/S41598-017-00774-9  0.655
2017 Foster JW, Wahlin K, Adams SM, Birk DE, Zack DJ, Chakravarti S. Cornea organoids from human induced pluripotent stem cells. Scientific Reports. 7: 41286. PMID 28128337 DOI: 10.1038/Srep41286  0.593
2016 Wilson DR, Routkevitch D, Wahlin KJ, Zack DJ, Quinones-Hinojosa A, Green JJ. 494. Development of a pH Sensor to Probe Endosomal Buffering of Polymeric Nanoparticles Effective for Gene Delivery Molecular Therapy. 24: S196. DOI: 10.1016/S1525-0016(16)33303-2  0.478
2015 Maruotti J, Sripathi SR, Bharti K, Fuller J, Wahlin KJ, Ranganathan V, Sluch VM, Berlinicke CA, Davis J, Kim C, Zhao L, Wan J, Qian J, Corneo B, Temple S, et al. Small-molecule-directed, efficient generation of retinal pigment epithelium from human pluripotent stem cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 26269569 DOI: 10.1073/Pnas.1422818112  0.711
2014 Ranganathan V, Wahlin K, Maruotti J, Zack DJ. Expansion of the CRISPR-Cas9 genome targeting space through the use of H1 promoter-expressed guide RNAs. Nature Communications. 5: 4516. PMID 25105359 DOI: 10.1038/Ncomms5516  0.466
2014 Wahlin KJ, Maruotti J, Zack DJ. Modeling retinal dystrophies using patient-derived induced pluripotent stem cells. Advances in Experimental Medicine and Biology. 801: 157-64. PMID 24664693 DOI: 10.1007/978-1-4614-3209-8_20  0.666
2014 Masuda T, Wahlin K, Wan J, Hu J, Maruotti J, Yang X, Iacovelli J, Wolkow N, Kist R, Dunaief JL, Qian J, Zack DJ, Esumi N. Transcription factor SOX9 plays a key role in the regulation of visual cycle gene expression in the retinal pigment epithelium. The Journal of Biological Chemistry. 289: 12908-21. PMID 24634209 DOI: 10.1074/Jbc.M114.556738  0.717
2013 Bhise NS, Wahlin KJ, Zack DJ, Green JJ. Evaluating the potential of poly(beta-amino ester) nanoparticles for reprogramming human fibroblasts to become induced pluripotent stem cells. International Journal of Nanomedicine. 8: 4641-58. PMID 24348039 DOI: 10.2147/Ijn.S53830  0.579
2013 Wahlin KJ, Enke RA, Fuller JA, Kalesnykas G, Zack DJ, Merbs SL. Epigenetics and cell death: DNA hypermethylation in programmed retinal cell death. Plos One. 8: e79140. PMID 24244436 DOI: 10.1371/Journal.Pone.0079140  0.76
2013 Zhang L, Wahlin K, Li Y, Masuda T, Yang Z, Zack DJ, Esumi N. RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors. Molecular Vision. 19: 1371-86. PMID 23805044  0.714
2013 Maruotti J, Wahlin K, Gorrell D, Bhutto I, Lutty G, Zack DJ. A simple and scalable process for the differentiation of retinal pigment epithelium from human pluripotent stem cells. Stem Cells Translational Medicine. 2: 341-54. PMID 23585288 DOI: 10.5966/Sctm.2012-0106  0.645
2013 Lumayag S, Haldin CE, Corbett NJ, Wahlin KJ, Cowan C, Turturro S, Larsen PE, Kovacs B, Witmer PD, Valle D, Zack DJ, Nicholson DA, Xu S. Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proceedings of the National Academy of Sciences of the United States of America. 110: E507-16. PMID 23341629 DOI: 10.1073/Pnas.1212655110  0.563
2010 Wahlin KJ, Hackler L, Adler R, Zack DJ. Alternative splicing of neuroligin and its protein distribution in the outer plexiform layer of the chicken retina. The Journal of Comparative Neurology. 518: 4938-62. PMID 21031560 DOI: 10.1002/Cne.22499  0.697
2008 Huang H, Wahlin KJ, McNally M, Irving ND, Adler R. Developmental regulation of muscleblind-like (MBNL) gene expression in the chicken embryo retina. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 286-96. PMID 18095352 DOI: 10.1002/Dvdy.21408  0.626
2008 Wahlin KJ, Moreira EF, Huang H, Yu N, Adler R. Molecular dynamics of photoreceptor synapse formation in the developing chick retina. The Journal of Comparative Neurology. 506: 822-37. PMID 18076030 DOI: 10.1002/Cne.21582  0.599
2004 Wahlin KJ, Lim L, Grice EA, Campochiaro PA, Zack DJ, Adler R. A method for analysis of gene expression in isolated mouse photoreceptor and Müller cells. Molecular Vision. 10: 366-75. PMID 15205663  0.689
2001 Wahlin KJ, Adler R, Zack DJ, Campochiaro PA. Neurotrophic signaling in normal and degenerating rodent retinas. Experimental Eye Research. 73: 693-701. PMID 11747369 DOI: 10.1006/Exer.2001.1078  0.67
2000 Hackett SF, Ozaki H, Strauss RW, Wahlin K, Suri C, Maisonpierre P, Yancopoulos G, Campochiaro PA. Angiopoietin 2 expression in the retina: upregulation during physiologic and pathologic neovascularization. Journal of Cellular Physiology. 184: 275-84. PMID 10911358 DOI: 10.1002/1097-4652(200009)184:3<275::Aid-Jcp1>3.0.Co;2-7  0.457
2000 Wahlin KJ, Campochiaro PA, Zack DJ, Adler R. Neurotrophic factors cause activation of intracellular signaling pathways in Müller cells and other cells of the inner retina, but not photoreceptors. Investigative Ophthalmology & Visual Science. 41: 927-36. PMID 10711715  0.68
2000 Mathura JR, Jafari N, Chang JT, Hackett SF, Wahlin KJ, Della NG, Okamoto N, Zack DJ, Campochiaro PA. Bone morphogenetic proteins-2 and -4: negative growth regulators in adult retinal pigmented epithelium. Investigative Ophthalmology & Visual Science. 41: 592-600. PMID 10670493  0.581
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