| Year |
Citation |
Score |
| 2020 |
Wurm H, Attfield K, Iversen AK, Gold R, Fugger L, Haghikia A. Recovery from COVID-19 in a B-cell-depleted multiple sclerosis patient. Multiple Sclerosis (Houndmills, Basingstoke, England). 1352458520943791. PMID 32762494 DOI: 10.1177/1352458520943791 |
0.312 |
|
| 2020 |
Huang J, Khademi M, Fugger L, Lindhe Ö, Novakova L, Axelsson M, Malmeström C, Constantinescu C, Lycke J, Piehl F, Olsson T, Kockum I. Inflammation-related plasma and CSF biomarkers for multiple sclerosis. Proceedings of the National Academy of Sciences of the United States of America. PMID 32457139 DOI: 10.1073/pnas.1912839117 |
0.308 |
|
| 2020 |
Faergeman SL, Evans H, Attfield KE, Desel C, Kuttikkatte SB, Sommerlund M, Jensen LT, Frokiaer J, Friese MA, Matthews PM, Luchtenborg C, Brügger B, Oturai AB, Dendrou CA, Fugger L. A novel neurodegenerative spectrum disorder in patients with MLKL deficiency. Cell Death & Disease. 11: 303. PMID 32358523 DOI: 10.1038/s41419-020-2494-0 |
0.328 |
|
| 2020 |
Pré MFd, Blazevski J, Dewan AE, Stamnaes J, Kanduri C, Sandve GK, Johannesen MK, Lindstad CB, Hnida K, Fugger L, Melino G, QS, Sollid LM. B cell tolerance and antibody production to the celiac disease autoantigen transglutaminase 2. Journal of Experimental Medicine. 217. PMID 31727780 DOI: 10.1084/Jem.20190860 |
0.346 |
|
| 2019 |
Ooi JD, Jiang JH, Eggenhuizen PJ, Chua LL, van Timmeren M, Loh KL, O'Sullivan KM, Gan PY, Zhong Y, Tsyganov K, Shochet LR, Ryan J, Stegeman CA, Fugger L, Reid HH, et al. A plasmid-encoded peptide from Staphylococcus aureus induces anti-myeloperoxidase nephritogenic autoimmunity. Nature Communications. 10: 3392. PMID 31358739 DOI: 10.1038/s41467-019-11255-0 |
0.359 |
|
| 2018 |
Dendrou CA, Petersen J, Rossjohn J, Fugger L. HLA variation and disease Nature Reviews Immunology. 18: 325-339. PMID 29292391 DOI: 10.1038/Nri.2017.143 |
0.383 |
|
| 2018 |
Ooi JD, Petersen J, Tan YH, Huynh M, Willett ZJ, Dudek NL, Eggenhuizen PJ, Loh KL, Watson KA, Gan P, Handel A, Hudson BG, Fugger L, Power DA, Holt SG, et al. Dominant protection from HLA-mediated autoimmune disease is conferred by antigen specific regulatory T cells Pathology. 50: S46-S47. DOI: 10.1016/J.Pathol.2017.12.112 |
0.411 |
|
| 2017 |
Regev A, Teichmann SA, Lander ES, Amit I, Benoist C, Birney E, Bodenmiller B, Campbell PJ, Carninci P, Clatworthy M, Clevers H, Deplancke B, Dunham I, Eberwine J, Eils R, ... ... Fugger L, et al. Science Forum: The Human Cell Atlas. Elife. 6. PMID 29206104 DOI: 10.7554/Elife.27041 |
0.304 |
|
| 2017 |
Dendrou CA, Fugger L. Immunomodulation in multiple sclerosis: promises and pitfalls. Current Opinion in Immunology. 49: 37-43. PMID 28926740 DOI: 10.1016/j.coi.2017.08.013 |
0.339 |
|
| 2017 |
Cortes A, Dendrou CA, Motyer A, Jostins L, Vukcevic D, Dilthey A, Donnelly P, Leslie S, Fugger L, McVean G. Bayesian analysis of genetic association across tree-structured routine healthcare data in the UK Biobank. Nature Genetics. PMID 28759005 DOI: 10.1038/Ng.3926 |
0.315 |
|
| 2017 |
Kaur G, Gras S, Mobbs JI, Vivian JP, Cortes A, Barber T, Kuttikkatte SB, Jensen LT, Attfield KE, Dendrou CA, Carrington M, McVean G, Purcell AW, Rossjohn J, Fugger L. Structural and regulatory diversity shape HLA-C protein expression levels. Nature Communications. 8: 15924. PMID 28649982 DOI: 10.1038/Ncomms15924 |
0.33 |
|
| 2017 |
Ooi JD, Petersen J, Tan YH, Huynh M, Willett ZJ, Ramarathinam SH, Eggenhuizen PJ, Loh KL, Watson KA, Gan PY, Alikhan MA, Dudek NL, Handel A, Hudson BG, Fugger L, et al. Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells. Nature. PMID 28467828 DOI: 10.1038/Nature22329 |
0.428 |
|
| 2016 |
Dendrou CA, Cortes A, Shipman L, Evans HG, Attfield KE, Jostins L, Barber T, Kaur G, Kuttikkatte SB, Leach OA, Desel C, Faergeman SL, Cheeseman J, Neville MJ, Sawcer S, ... ... Fugger L, et al. Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity. Science Translational Medicine. 8: 363ra149. PMID 27807284 DOI: 10.1126/Scitranslmed.Aag1974 |
0.321 |
|
| 2016 |
Grodeland G, Fredriksen AB, Løset GÅ, Vikse E, Fugger L, Bogen B. Antigen Targeting to Human HLA Class II Molecules Increases Efficacy of DNA Vaccination Journal of Immunology. 197: 3575-3585. PMID 27671110 DOI: 10.4049/Jimmunol.1600893 |
0.31 |
|
| 2016 |
Jönsson P, Southcombe JH, Santos AM, Huo J, Fernandes RA, McColl J, Lever M, Evans EJ, Hudson A, Chang VT, Hanke T, Godkin A, Dunne PD, Horrocks MH, Palayret M, ... ... Fugger L, et al. Remarkably low affinity of CD4/peptide-major histocompatibility complex class II protein interactions. Proceedings of the National Academy of Sciences of the United States of America. PMID 27114505 DOI: 10.1073/Pnas.1513918113 |
0.33 |
|
| 2015 |
Dendrou CA, Fugger L, Friese MA. Immunopathology of multiple sclerosis Nature Reviews Immunology. 15: 545-558. PMID 26250739 DOI: 10.1038/nri3871 |
0.323 |
|
| 2014 |
Gold R, Fugger L. Multiple sclerosis: insights into pathophysiology and novel therapeutic avenues. Experimental Neurology. 262: 1. PMID 24751800 DOI: 10.1016/J.Expneurol.2014.04.012 |
0.312 |
|
| 2014 |
Tenzer S, Crawford H, Pymm P, Gifford R, Sreenu VB, Weimershaus M, de Oliveira T, Burgevin A, Gerstoft J, Akkad N, Lunn D, Fugger L, Bell J, Schild H, van Endert P, et al. HIV-1 adaptation to antigen processing results in population-level immune evasion and affects subtype diversification. Cell Reports. 7: 448-63. PMID 24726370 DOI: 10.1016/j.celrep.2014.03.031 |
0.327 |
|
| 2014 |
Friese MA, Schattling B, Fugger L. Mechanisms of neurodegeneration and axonal dysfunction in multiple sclerosis. Nature Reviews. Neurology. 10: 225-38. PMID 24638138 DOI: 10.1038/nrneurol.2014.37 |
0.308 |
|
| 2013 |
Dendrou CA, Bell JI, Fugger L. A clinical conundrum: the detrimental effect of TNF antagonists in multiple sclerosis. Pharmacogenomics. 14: 1397-404. PMID 24024893 DOI: 10.2217/pgs.13.140 |
0.33 |
|
| 2013 |
Attfield KE, Fugger L. TCR transgenic mice that shed light on immune and environmental regulators in multiple sclerosis. Journal of Immunology (Baltimore, Md. : 1950). 190: 3015-7. PMID 23526826 DOI: 10.4049/jimmunol.1300427 |
0.334 |
|
| 2013 |
Ooi JD, Chang J, O'Sullivan KM, Pedchenko V, Hudson BG, Vandenbark AA, Fugger L, Holdsworth SR, Kitching AR. The HLA-DRB1*15:01-restricted Goodpasture's T cell epitope induces GN. Journal of the American Society of Nephrology : Jasn. 24: 419-31. PMID 23411782 DOI: 10.1681/Asn.2012070705 |
0.404 |
|
| 2013 |
Dendrou CA, Bell JI, Fugger L. Weighing in on autoimmune disease: Big data tip the scale. Nature Medicine. 19: 138-9. PMID 23389608 DOI: 10.1038/nm.3087 |
0.345 |
|
| 2013 |
Arun T, Tomassini V, Sbardella E, de Ruiter MB, Matthews L, Leite MI, Gelineau-Morel R, Cavey A, Vergo S, Craner M, Fugger L, Rovira A, Jenkinson M, Palace J. Targeting ASIC1 in primary progressive multiple sclerosis: evidence of neuroprotection with amiloride. Brain : a Journal of Neurology. 136: 106-15. PMID 23365093 DOI: 10.1093/Brain/Aws325 |
0.301 |
|
| 2013 |
Kaur G, Trowsdale J, Fugger L. Natural killer cells and their receptors in multiple sclerosis. Brain : a Journal of Neurology. 136: 2657-76. PMID 22734127 DOI: 10.1093/brain/aws159 |
0.364 |
|
| 2012 |
Ooi JD, Chang J, Hickey MJ, Borza DB, Fugger L, Holdsworth SR, Kitching AR. The immunodominant myeloperoxidase T-cell epitope induces local cell-mediated injury in antimyeloperoxidase glomerulonephritis. Proceedings of the National Academy of Sciences of the United States of America. 109: E2615-24. PMID 22955884 DOI: 10.1073/pnas.1210147109 |
0.358 |
|
| 2012 |
Gregory AP, Dendrou CA, Attfield KE, Haghikia A, Xifara DK, Butter F, Poschmann G, Kaur G, Lambert L, Leach OA, Prömel S, Punwani D, Felce JH, Davis SJ, Gold R, ... ... Fugger L, et al. TNF receptor 1 genetic risk mirrors outcome of anti-TNF therapy in multiple sclerosis. Nature. 488: 508-11. PMID 22801493 DOI: 10.1038/Nature11307 |
0.353 |
|
| 2012 |
Attfield KE, Dendrou CA, Fugger L. Bridging the gap from genetic association to functional understanding: the next generation of mouse models of multiple sclerosis. Immunological Reviews. 248: 10-22. PMID 22725951 DOI: 10.1111/j.1600-065X.2012.01132.x |
0.358 |
|
| 2012 |
Wekerle H, Flügel A, Fugger L, Schett G, Serreze D. Autoimmunity's next top models. Nature Medicine. 18: 66-70. PMID 22227675 DOI: 10.1038/nm.2635 |
0.307 |
|
| 2011 |
Du Pré MF, Kozijn AE, van Berkel LA, ter Borg MN, Lindenbergh-Kortleve D, Jensen LT, Kooy-Winkelaar Y, Koning F, Boon L, Nieuwenhuis EE, Sollid LM, Fugger L, Samsom JN. Tolerance to ingested deamidated gliadin in mice is maintained by splenic, type 1 regulatory T cells. Gastroenterology. 141: 610-20, 620.e1-2. PMID 21683079 DOI: 10.1053/j.gastro.2011.04.048 |
0.372 |
|
| 2011 |
McMahon RM, Friis L, Siebold C, Friese MA, Fugger L, Jones EY. Structure of HLA-A*0301 in complex with a peptide of proteolipid protein: insights into the role of HLA-A alleles in susceptibility to multiple sclerosis. Acta Crystallographica. Section D, Biological Crystallography. 67: 447-54. PMID 21543847 DOI: 10.1107/S0907444911007888 |
0.402 |
|
| 2010 |
Nika K, Soldani C, Salek M, Paster W, Gray A, Etzensperger R, Fugger L, Polzella P, Cerundolo V, Dushek O, Höfer T, Viola A, Acuto O. Constitutively active Lck kinase in T cells drives antigen receptor signal transduction. Immunity. 32: 766-77. PMID 20541955 DOI: 10.1016/J.Immuni.2010.05.011 |
0.308 |
|
| 2009 |
Friese MA, Fugger L. Pathogenic CD8(+) T cells in multiple sclerosis. Annals of Neurology. 66: 132-41. PMID 19743458 DOI: 10.1002/ana.21744 |
0.422 |
|
| 2009 |
Fugger L, Friese MA, Bell JI. From genes to function: the next challenge to understanding multiple sclerosis. Nature Reviews. Immunology. 9: 408-17. PMID 19444306 DOI: 10.1038/nri2554 |
0.319 |
|
| 2009 |
Call MJ, Xing X, Cuny GD, Seth NP, Altmann DM, Fugger L, Krogsgaard M, Stein RL, Wucherpfennig KW. In vivo enhancement of peptide display by MHC class II molecules with small molecule catalysts of peptide exchange. Journal of Immunology (Baltimore, Md. : 1950). 182: 6342-52. PMID 19414787 DOI: 10.4049/Jimmunol.0803464 |
0.327 |
|
| 2009 |
Harkiolaki M, Holmes SL, Svendsen P, Gregersen JW, Jensen LT, McMahon R, Friese MA, van Boxel G, Etzensperger R, Tzartos JS, Kranc K, Sainsbury S, Harlos K, Mellins ED, Palace J, ... ... Fugger L, et al. T cell-mediated autoimmune disease due to low-affinity crossreactivity to common microbial peptides. Immunity. 30: 348-57. PMID 19303388 DOI: 10.1016/j.immuni.2009.01.009 |
0.398 |
|
| 2009 |
Patel SD, Parry S, Cope AP, Congia M, Fugger L, Sonderstrup-McDevitt G. Identification of immunodominant T-cell epitopes of human glutamic acid decarboxylase 65 using HLA-DR4 transgenic mice Experimental and Clinical Endocrinology & Diabetes. 105: 49-49. DOI: 10.1055/S-0029-1211868 |
0.362 |
|
| 2009 |
Pré MFd, Berkel Lv, Borg Mt, Torp-Jensen L, Yvonne E, Kooy-Winkelaar M, Koning F, Sollid LM, Nieuwenhuis E, Fugger L, Samsom JN. 353 Localization and Phenotype of the Gliadin-Specific T-Cell Response After Oral Gliadin Intake in Mice Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)60256-0 |
0.371 |
|
| 2008 |
Friese MA, Jakobsen KB, Friis L, Etzensperger R, Craner MJ, McMahon RM, Jensen LT, Huygelen V, Jones EY, Bell JI, Fugger L. Opposing effects of HLA class I molecules in tuning autoreactive CD8+ T cells in multiple sclerosis. Nature Medicine. 14: 1227-35. PMID 18953350 DOI: 10.1038/nm.1881 |
0.393 |
|
| 2008 |
Etzensperger R, McMahon RM, Jones EY, Fugger L. Dissection of the multiple sclerosis associated DR2 haplotype. Journal of Autoimmunity. 31: 201-7. PMID 18513924 DOI: 10.1016/j.jaut.2008.04.016 |
0.453 |
|
| 2008 |
Moisini I, Nguyen P, Fugger L, Geiger TL. Redirecting therapeutic T cells against myelin-specific T lymphocytes using a humanized myelin basic protein-HLA-DR2-zeta chimeric receptor. Journal of Immunology (Baltimore, Md. : 1950). 180: 3601-11. PMID 18292588 DOI: 10.4049/Jimmunol.180.5.3601 |
0.399 |
|
| 2008 |
Tzartos JS, Friese MA, Craner MJ, Palace J, Newcombe J, Esiri MM, Fugger L. Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis. The American Journal of Pathology. 172: 146-55. PMID 18156204 DOI: 10.2353/ajpath.2008.070690 |
0.343 |
|
| 2008 |
Hansen BE, Andersson EC, Madsen LS, Engberg J, Søndergaard L, Svejgaard A, Fugger L. Functional characterization of HLA‐DRA11 0101/ DRB1* 0401 molecules expressed in Drosophila melanogaster cells Tissue Antigens. 51: 119-128. DOI: 10.1111/J.1399-0039.1998.Tb02957.X |
0.383 |
|
| 2007 |
Friese MA, Fugger L. T cells and microglia as drivers of multiple sclerosis pathology. Brain : a Journal of Neurology. 130: 2755-7. PMID 17956912 DOI: 10.1093/brain/awm246 |
0.391 |
|
| 2006 |
Friese MA, Jensen LT, Willcox N, Fugger L. Humanized mouse models for organ-specific autoimmune diseases. Current Opinion in Immunology. 18: 704-9. PMID 17008081 DOI: 10.1016/j.coi.2006.09.003 |
0.356 |
|
| 2006 |
Gregersen JW, Kranc KR, Ke X, Svendsen P, Madsen LS, Thomsen AR, Cardon LR, Bell JI, Fugger L. Functional epistasis on a common MHC haplotype associated with multiple sclerosis. Nature. 443: 574-7. PMID 17006452 DOI: 10.1038/nature05133 |
0.424 |
|
| 2006 |
Friese MA, Montalban X, Willcox N, Bell JI, Martin R, Fugger L. The value of animal models for drug development in multiple sclerosis. Brain : a Journal of Neurology. 129: 1940-52. PMID 16636022 DOI: 10.1093/brain/awl083 |
0.346 |
|
| 2006 |
Jones EY, Fugger L, Strominger JL, Siebold C. MHC class II proteins and disease: a structural perspective. Nature Reviews. Immunology. 6: 271-82. PMID 16557259 DOI: 10.1038/Nri1805 |
0.416 |
|
| 2006 |
Dzhambazov B, Nandakumar KS, Kihlberg J, Fugger L, Holmdahl R, Vestberg M. Therapeutic vaccination of active arthritis with a glycosylated collagen type II peptide in complex with MHC class II molecules. Journal of Immunology (Baltimore, Md. : 1950). 176: 1525-33. PMID 16424181 DOI: 10.4049/Jimmunol.176.3.1525 |
0.379 |
|
| 2006 |
Iversen AK, Stewart-Jones G, Learn GH, Christie N, Sylvester-Hviid C, Armitage AE, Kaul R, Beattie T, Lee JK, Li Y, Chotiyarnwong P, Dong T, Xu X, Luscher MA, MacDonald K, ... ... Fugger L, et al. Conflicting selective forces affect T cell receptor contacts in an immunodominant human immunodeficiency virus epitope. Nature Immunology. 7: 179-89. PMID 16388312 DOI: 10.1038/Ni1298 |
0.319 |
|
| 2006 |
Kort JJ, Kawamura K, Fugger L, Weissert R, Forsthuber TG. Efficient presentation of myelin oligodendrocyte glycoprotein peptides but not protein by astrocytes from HLA-DR2 and HLA-DR4 transgenic mice. Journal of Neuroimmunology. 173: 23-34. PMID 16386804 DOI: 10.1016/J.Jneuroim.2005.11.014 |
0.423 |
|
| 2005 |
Friese MA, Jones EY, Fugger L. MHC II molecules in inflammatory diseases: interplay of qualities and quantities. Trends in Immunology. 26: 559-61. PMID 16139566 DOI: 10.1016/j.it.2005.08.011 |
0.387 |
|
| 2005 |
Friese MA, Fugger L. Autoreactive CD8+ T cells in multiple sclerosis: a new target for therapy? Brain : a Journal of Neurology. 128: 1747-63. PMID 15975943 DOI: 10.1093/brain/awh578 |
0.389 |
|
| 2005 |
Holmes S, Friese MA, Siebold C, Jones EY, Bell J, Fugger L. Multiple sclerosis: MHC associations and therapeutic implications. Expert Reviews in Molecular Medicine. 7: 1-17. PMID 15710050 DOI: 10.1017/S1462399405008914 |
0.432 |
|
| 2005 |
Kranc KR, Taylor AM, Willcox N, Fugger L. Control of autoimmunity by "epitope theft". Trends in Molecular Medicine. 11: 1-4. PMID 15649815 DOI: 10.1016/j.molmed.2004.11.002 |
0.396 |
|
| 2004 |
Svendsen P, Andersen CB, Willcox N, Coyle AJ, Holmdahl R, Kamradt T, Fugger L. Tracking of proinflammatory collagen-specific T cells in early and late collagen-induced arthritis in humanized mice. Journal of Immunology (Baltimore, Md. : 1950). 173: 7037-45. PMID 15557201 DOI: 10.4049/Jimmunol.173.11.7037 |
0.392 |
|
| 2004 |
Rich C, Link JM, Zamora A, Jacobsen H, Meza-Romero R, Offner H, Jones R, Burrows GG, Fugger L, Vandenbark AA. Myelin oligodendrocyte glycoprotein-35-55 peptide induces severe chronic experimental autoimmune encephalomyelitis in HLA-DR2-transgenic mice. European Journal of Immunology. 34: 1251-61. PMID 15114658 DOI: 10.1002/Eji.200324354 |
0.414 |
|
| 2004 |
Gregersen JW, Holmes S, Fugger L. Humanized animal models for autoimmune diseases. Tissue Antigens. 63: 383-94. PMID 15104670 DOI: 10.1111/j.0001-2815.2004.00243.x |
0.394 |
|
| 2004 |
Siebold C, Hansen BE, Wyer JR, Harlos K, Esnouf RE, Svejgaard A, Bell JI, Strominger JL, Jones EY, Fugger L. Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy. Proceedings of the National Academy of Sciences of the United States of America. 101: 1999-2004. PMID 14769912 DOI: 10.1073/Pnas.0308458100 |
0.33 |
|
| 2004 |
Jensen LB, Riise E, Nielsen LK, Dziegiel M, Fugger L, Engberg J. Efficient purification of unique antibodies using peptide affinity-matrix columns. Journal of Immunological Methods. 284: 45-54. PMID 14736416 DOI: 10.1016/j.jim.2003.10.001 |
0.322 |
|
| 2003 |
Vandenbark AA, Rich C, Mooney J, Zamora A, Wang C, Huan J, Fugger L, Offner H, Jones R, Burrows GG. Recombinant TCR ligand induces tolerance to myelin oligodendrocyte glycoprotein 35-55 peptide and reverses clinical and histological signs of chronic experimental autoimmune encephalomyelitis in HLA-DR2 transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 171: 127-33. PMID 12816990 DOI: 10.4049/Jimmunol.171.1.127 |
0.366 |
|
| 2003 |
Davis SJ, Ikemizu S, Evans EJ, Fugger L, Bakker TR, van der Merwe PA. The nature of molecular recognition by T cells. Nature Immunology. 4: 217-24. PMID 12605231 DOI: 10.1038/Ni0303-217 |
0.345 |
|
| 2002 |
Lang HL, Jacobsen H, Ikemizu S, Andersson C, Harlos K, Madsen L, Hjorth P, Sondergaard L, Svejgaard A, Wucherpfennig K, Stuart DI, Bell JI, Jones EY, Fugger L. A functional and structural basis for TCR cross-reactivity in multiple sclerosis. Nature Immunology. 3: 940-3. PMID 12244309 DOI: 10.1038/Ni835 |
0.423 |
|
| 2002 |
Bäcklund J, Carlsen S, Höger T, Holm B, Fugger L, Kihlberg J, Burkhardt H, Holmdahl R. Predominant selection of T cells specific for the glycosylated collagen type II epitope (263-270) in humanized transgenic mice and in rheumatoid arthritis. Proceedings of the National Academy of Sciences of the United States of America. 99: 9960-5. PMID 12089323 DOI: 10.1073/pnas.132254199 |
0.406 |
|
| 2002 |
Fridkis-Hareli M, Santambrogio L, Stern JN, Fugger L, Brosnan C, Strominger JL. Novel synthetic amino acid copolymers that inhibit autoantigen-specific T cell responses and suppress experimental autoimmune encephalomyelitis. The Journal of Clinical Investigation. 109: 1635-43. PMID 12070311 DOI: 10.1172/Jci15402 |
0.374 |
|
| 2002 |
Manoury B, Mazzeo D, Fugger L, Viner N, Ponsford M, Streeter H, Mazza G, Wraith DC, Watts C. Destructive processing by asparagine endopeptidase limits presentation of a dominant T cell epitope in MBP. Nature Immunology. 3: 169-74. PMID 11812994 DOI: 10.1038/Ni754 |
0.326 |
|
| 2001 |
Fridkis-Hareli M, Stern JN, Fugger L, Strominger JL. Synthetic peptides that inhibit binding of the myelin basic protein 85-99 epitope to multiple sclerosis-associated HLA-DR2 molecules and MBP-specific T-cell responses. Human Immunology. 62: 753-63. PMID 11476898 DOI: 10.1016/S0198-8859(01)00279-8 |
0.424 |
|
| 2000 |
Fugger L. Human autoimmunity genes in mice. Current Opinion in Immunology. 12: 698-703. PMID 11102775 DOI: 10.1016/S0952-7915(00)00165-5 |
0.38 |
|
| 2000 |
Fugger L, Svejgaard A. Association of MHC and rheumatoid arthritis. HLA-DR4 and rheumatoid arthritis: studies in mice and men. Arthritis Research. 2: 208-11. PMID 11094431 DOI: 10.1186/ar89 |
0.35 |
|
| 2000 |
Fugger L. Joint-specific and systemic autoreactivity in the development of inflammatory arthritis. Arthritis Research. 2: 2-4. PMID 11094413 DOI: 10.1186/ar64 |
0.34 |
|
| 2000 |
Fridkis-Hareli M, Rosloniec EF, Fugger L, Strominger JL. Synthetic peptides that inhibit binding of the collagen type II 261-273 epitope to rheumatoid arthritis-associated HLA-DR1 and -DR4 molecules and collagen-specific T-cell responses. Human Immunology. 61: 640-50. PMID 10880734 DOI: 10.1016/S0198-8859(00)00126-9 |
0.409 |
|
| 2000 |
Krogsgaard M, Wucherpfennig KW, Cannella B, Hansen BE, Svejgaard A, Pyrdol J, Ditzel H, Raine C, Engberg J, Fugger L, Canella B. Visualization of myelin basic protein (MBP) T cell epitopes in multiple sclerosis lesions using a monoclonal antibody specific for the human histocompatibility leukocyte antigen (HLA)-DR2-MBP 85-99 complex. The Journal of Experimental Medicine. 191: 1395-412. PMID 10770805 DOI: 10.1084/Jem.191.8.1395 |
0.42 |
|
| 2000 |
Rognan D, Stryhn A, Fugger L, Lyngbaek S, Engberg J, Andersen PS, Buus S. Modeling the interactions of a peptide-major histocompatibility class I ligand with its receptors. I. Recognition by two alpha beta T cell receptors. Journal of Computer-Aided Molecular Design. 14: 53-69. PMID 10702925 DOI: 10.1023/A:1008142830353 |
0.34 |
|
| 1999 |
Madsen LS, Andersson EC, Jansson L, krogsgaard M, Andersen CB, Engberg J, Strominger JL, Svejgaard A, Hjorth JP, Holmdahl R, Wucherpfennig KW, Fugger L. A humanized model for multiple sclerosis using HLA-DR2 and a human T-cell receptor. Nature Genetics. 23: 343-7. PMID 10610182 DOI: 10.1038/15525 |
0.471 |
|
| 1999 |
Norgaard L, Fugger L, Madsen HO, Svejgaard A. Identification of 4 different alternatively spliced HLA-A transcripts. Tissue Antigens. 54: 370-8. PMID 10551420 DOI: 10.1034/j.1399-0039.1999.540406.x |
0.321 |
|
| 1999 |
Oturai A, Larsen F, Ryder LP, Madsen HO, Hillert J, Fredrikson S, Sandberg-Wollheim M, Laaksonen M, Koch-Henriksen N, Sawcer S, Fugger L, Sorensen PS, Svejgaard A. Linkage and association analysis of susceptibility regions on chromosomes 5 and 6 in 106 Scandinavian sibling pair families with multiple sclerosis. Annals of Neurology. 46: 612-6. PMID 10514098 DOI: 10.1002/1531-8249(199910)46:4<612::AID-ANA9>3.0.CO;2-W |
0.318 |
|
| 1999 |
Madsen L, Labrecque N, Engberg J, Dierich A, Svejgaard A, Benoist C, Mathis D, Fugger L. Mice lacking all conventional MHC class II genes. Proceedings of the National Academy of Sciences of the United States of America. 96: 10338-43. PMID 10468609 DOI: 10.1073/Pnas.96.18.10338 |
0.356 |
|
| 1999 |
Quarsten H, Molberg O, Fugger L, McAdam SN, Sollid LM. HLA binding and T cell recognition of a tissue transglutaminase-modified gliadin epitope. European Journal of Immunology. 29: 2506-14. PMID 10458765 DOI: 10.1002/(SICI)1521-4141(199908)29:08<2506::AID-IMMU2506>3.0.CO;2-9 |
0.363 |
|
| 1999 |
Holmdahl R, Andersson EC, Andersen CB, Svejgaard A, Fugger L. Transgenic mouse models of rheumatoid arthritis. Immunological Reviews. 169: 161-73. PMID 10450516 DOI: 10.1111/j.1600-065X.1999.tb01314.x |
0.397 |
|
| 1998 |
Fridkis-Hareli M, Rosloniec EF, Fugger L, Strominger JL. Synthetic amino acid copolymers that bind to HLA-DR proteins and inhibit type II collagen-reactive T cell clones. Proceedings of the National Academy of Sciences of the United States of America. 95: 12528-31. PMID 9770519 DOI: 10.1073/Pnas.95.21.12528 |
0.381 |
|
| 1998 |
Andersson EC, Hansen BE, Jacobsen H, Madsen LS, Andersen CB, Engberg J, Rothbard JB, McDevitt GS, Malmström V, Holmdahl R, Svejgaard A, Fugger L. Definition of MHC and T cell receptor contacts in the HLA-DR4restricted immunodominant epitope in type II collagen and characterization of collagen-induced arthritis in HLA-DR4 and human CD4 transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 95: 7574-9. PMID 9636191 DOI: 10.1073/pnas.95.13.7574 |
0.423 |
|
| 1998 |
Kjellén P, Brunsberg U, Broddefalk J, Hansen B, Vestberg M, Ivarsson I, Engström A, Svejgaard A, Kihlberg J, Fugger L, Holmdahl R. The structural basis of MHC control of collagen-induced arthritis; binding of the immunodominant type II collagen 256-270 glycopeptide to H-2Aq and H-2Ap molecules. European Journal of Immunology. 28: 755-67. PMID 9521085 DOI: 10.1002/(SICI)1521-4141(199802)28:02<755::AID-IMMU755>3.0.CO;2-2 |
0.364 |
|
| 1997 |
Fugger L, Svejgaard A. The HLA-DQ7 and -DQ8 associations in DR4-positive rheumatoid arthritis patients. A combined analysis of data available in the literature. Tissue Antigens. 50: 494-500. PMID 9389324 DOI: 10.1111/J.1399-0039.1997.Tb02905.X |
0.341 |
|
| 1997 |
Patel SD, Cope AP, Congia M, Chen TT, Kim E, Fugger L, Wherrett D, Sonderstrup-McDevitt G. Identification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR(alpha1*0101,beta1*0401) transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 94: 8082-7. PMID 9223318 DOI: 10.1073/pnas.94.15.8082 |
0.438 |
|
| 1997 |
Reiter Y, Di Carlo A, Fugger L, Engberg J, Pastan I. Peptide-specific killing of antigen-presenting cells by a recombinant antibody-toxin fusion protein targeted to major histocompatibility complex/peptide class I complexes with T cell receptor-like specificity. Proceedings of the National Academy of Sciences of the United States of America. 94: 4631-6. PMID 9114042 DOI: 10.1073/PNAS.94.9.4631 |
0.369 |
|
| 1996 |
Röpke M, Hald J, Guldberg P, Zeuthen J, Nørgaard L, Fugger L, Svejgaard A, Van der Burg S, Nijman HW, Melief CJ, Claesson MH. Spontaneous human squamous cell carcinomas are killed by a human cytotoxic T lymphocyte clone recognizing a wild-type p53-derived peptide. Proceedings of the National Academy of Sciences of the United States of America. 93: 14704-7. PMID 8962118 DOI: 10.1073/pnas.93.25.14704 |
0.345 |
|
| 1996 |
Stryhn A, Andersen PS, Pedersen LO, Svejgaard A, Holm A, Thorpe CJ, Fugger L, Buus S, Engberg J. Shared fine specificity between T-cell receptors and an antibody recognizing a peptide/major histocompatibility class I complex. Proceedings of the National Academy of Sciences of the United States of America. 93: 10338-42. PMID 8816801 DOI: 10.1073/pnas.93.19.10338 |
0.383 |
|
| 1996 |
Andersen PS, Stryhn A, Hansen BE, Fugger L, Engberg J, Buus S. A recombinant antibody with the antigen-specific, major histocompatibility complex-restricted specificity of T cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 1820-4. PMID 8700842 DOI: 10.1073/pnas.93.5.1820 |
0.37 |
|
| 1996 |
Cope AP, Patel S, Congia M, Fugger L, Sonderstrup-McDevitt G. O389 - Collagen induced arthritis in HLA-DR4/human CD4 transgenic mice lacking mouse MHC class II molecules Human Immunology. 47: 73. DOI: 10.1016/0198-8859(96)85084-1 |
0.347 |
|
| 1994 |
van Endert PM, Liblau RS, Patel SD, Fugger L, Lopez T, Pociot F, Nerup J, McDevitt HO. Major histocompatibility complex-encoded antigen processing gene polymorphism in IDDM. Diabetes. 43: 110-7. PMID 7903260 DOI: 10.2337/Diab.43.1.110 |
0.367 |
|
| 1993 |
Tisch R, Yang XD, Singer SM, Liblau RS, Fugger L, McDevitt HO. Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. Nature. 366: 72-5. PMID 8232539 DOI: 10.1038/366072A0 |
0.334 |
|
| 1993 |
Liblau R, van Endert PM, Sandberg-Wollheim M, Patel SD, Lopez MT, Land S, Fugger L, McDevitt HO. Antigen processing gene polymorphisms in HLA-DR2 multiple sclerosis. Neurology. 43: 1192-7. PMID 7909590 DOI: 10.1212/Wnl.43.6.1192 |
0.385 |
|
| 1992 |
Morling N, Dalhoff K, Fugger L, Georgsen J, Jakobsen B, Ranek L, Odum N, Svejgaard A. DNA polymorphism of HLA class II genes in primary biliary cirrhosis. Immunogenetics. 35: 112-6. PMID 1735557 DOI: 10.1007/BF00189520 |
0.369 |
|
| 1992 |
Morling N, Sandberg-Wollheim M, Fugger L, Georgsen J, Hylding-Nielsen JJ, Madsen HO, Rieneck K, Ryder L, Svejgaard A. Immunogenetics of multiple sclerosis and optic neuritis: DNA polymorphism of HLA class II genes. Immunogenetics. 35: 391-4. PMID 1349586 DOI: 10.1007/BF00179795 |
0.332 |
|
| 1991 |
Morling N, Friis J, Fugger L, Georgsen J, Heilmann C, Pedersen FK, Odum N, Svejgaard A. DNA polymorphism of HLA class II genes in pauciarticular juvenile rheumatoid arthritis. Tissue Antigens. 38: 16-23. PMID 1681599 DOI: 10.1111/J.1399-0039.1991.Tb02030.X |
0.315 |
|
| 1990 |
Odum N, Morling N, Georgsen J, Jakobsen BK, Frentz G, Jensen GF, Fugger L, Svejgaard A. HLA-DP antigens in patients with alopecia areata. Tissue Antigens. 35: 114-7. PMID 2375044 DOI: 10.1111/J.1399-0039.1990.Tb01766.X |
0.329 |
|
| 1990 |
Fugger L, Ryder LP, Morling N, Odum N, Friis J, Pedersen FK, Heilmann C, Sandberg-Wollheim M, Svejgaard A. DNA typing for HLA-DPB1*02 and -DPB1*04 in multiple sclerosis and juvenile rheumatoid arthritis. Immunogenetics. 32: 150-6. PMID 2228045 DOI: 10.1007/BF02114968 |
0.353 |
|
| 1990 |
Fugger L, Morling N, Ryder LP, Sandberg-Wollheim M, Svejgaard A. Failure to demonstrate human T cell lymphotropic virus type I in multiple sclerosis patients. The Journal of General Virology. 71: 1103-7. PMID 2189023 DOI: 10.1099/0022-1317-71-5-1103 |
0.32 |
|
| 1990 |
Fugger L, Sandberg-Wollheim M, Morling N, Ryder LP, Svejgaard A. The germline repertoire of T-cell receptor beta chain genes in patients with relapsing/remitting multiple sclerosis or optic neuritis. Immunogenetics. 31: 278-80. PMID 2139432 DOI: 10.1007/BF00204901 |
0.318 |
|
| 1990 |
Fugger L, Morling N, Ryder LP, Jakobsen BK, Svejgaard A, Spies T, Strominger JL. Restriction fragment length polymorphism (RFLP) of two HLA-B-associated transcripts (BATs) genes in healthy Danes. Tissue Antigens. 36: 57-61. PMID 1980160 DOI: 10.1111/J.1399-0039.1990.Tb01800.X |
0.333 |
|
| 1989 |
Fugger L, Morling N, Ryder LP, Odum N, Georgsen J, Svejgaard A. Typing for HLA-DPB1*03 and HLA-DPB1*06 using allele-specific DNA in vitro amplification and allele-specific oligonucleotide probes. Detection of "new" DPB1*06 variants. Immunogenetics. 30: 208-13. PMID 2777339 DOI: 10.1007/BF02421208 |
0.301 |
|
| 1989 |
Fugger L, Morling N, Bendtzen K, Ryder L, Andersen V, Heilman C, Karup Pedersen F, Friis J, Halbert P, Svejgaard A. IL-6 gene polymorphism in rheumatoid arthritis, pauciarticular juvenile rheumatoid arthritis, systemic lupus erythematosus, and in healthy Danes. Journal of Immunogenetics. 16: 461-5. PMID 2577114 DOI: 10.1111/J.1744-313X.1989.Tb00495.X |
0.301 |
|
| 1989 |
Fugger L, Morling N, Ryder LP, Georgsen J, Jakobsen BK, Svejgaard A, Andersen V, Oxholm P, Karup Pedersen F, Friis J. NcoI restriction fragment length polymorphism (RFLP) of the tumor necrosis factor (TNF alpha) region in four autoimmune diseases. Tissue Antigens. 34: 17-22. PMID 2573169 DOI: 10.1111/J.1399-0039.1989.Tb01712.X |
0.314 |
|
| 1989 |
Fugger L, Morling N, Ryder LP, Platz P, Georgsen J, Jakobsen BK, Svejgaard A, Dalhoff K, Ranek L. NcoI restriction fragment length polymorphism (RFLP) of the tumour necrosis factor (TNF alpha) region in primary biliary cirrhosis and in healthy Danes. Scandinavian Journal of Immunology. 30: 185-9. PMID 2569760 DOI: 10.1111/J.1365-3083.1989.Tb01200.X |
0.304 |
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