Thomas G. Forsthuber - Publications

Affiliations: 
Biology The University of Texas at San Antonio, San Antonio, TX, United States 
Area:
Cell Biology, Immunology, Neuroscience Biology

92 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Moseley CE, Virupakshaiah A, Forsthuber TG, Steinman L, Waubant E, Zamvil SS. MOG CNS Autoimmunity and MOGAD. Neurology(R) Neuroimmunology & Neuroinflammation. 11: e200275. PMID 38996203 DOI: 10.1212/NXI.0000000000200275  0.359
2024 Asmis R, Medrano MT, Chase Huizar C, Griffith WP, Forsthuber TG. Dietary Supplementation with 23-Hydroxy Ursolic Acid Reduces the Severity and Incidence of Acute Experimental Autoimmune Encephalomyelitis (EAE) in a Murine Model of Multiple Sclerosis. Nutrients. 16. PMID 38337633 DOI: 10.3390/nu16030348  0.337
2022 Naoun AA, Raphael I, Forsthuber TG. Immunoregulation via Cell Density and Quorum Sensing-like Mechanisms: An Underexplored Emerging Field with Potential Translational Implications. Cells. 11. PMID 35954285 DOI: 10.3390/cells11152442  0.334
2021 Chase Huizar C, Ji N, Reddick R, Ostroff GR, Forsthuber TG. Glucan particles as a novel adjuvant for the induction of experimental autoimmune encephalomyelitis. Cellular Immunology. 366: 104383. PMID 34111646 DOI: 10.1016/j.cellimm.2021.104383  0.737
2021 Manouchehri N, Hussain RZ, Cravens PD, Esaulova E, Artyomov MN, Edelson BT, Wu GF, Cross AH, Doelger R, Loof N, Eagar TN, Forsthuber TG, Calvier L, Herz J, Stüve O. CD11cCD88CD317 myeloid cells are critical mediators of persistent CNS autoimmunity. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33785592 DOI: 10.1073/pnas.2014492118  0.366
2020 Negron A, Stüve O, Forsthuber TG. Ectopic Lymphoid Follicles in Multiple Sclerosis: Centers for Disease Control? Frontiers in Neurology. 11: 607766. PMID 33363512 DOI: 10.3389/fneur.2020.607766  0.383
2020 Manouchehri N, Hussain RZ, Cravens PD, Doelger R, Greenberg BM, Okuda DT, Forsthuber TG, Eagar TN, Stüve O. Limitations of cell-lineage-specific non-dynamic gene recombination in CD11c.CreITGA4 mice. Journal of Neuroimmunology. 344: 577245. PMID 32335319 DOI: 10.1016/J.Jneuroim.2020.577245  0.308
2020 Raphael I, Joern RR, Forsthuber TG. Memory CD4 T Cells in Immunity and Autoimmune Diseases. Cells. 9. PMID 32106536 DOI: 10.3390/Cells9030531  0.456
2019 Raphael I, Gomez-Rivera F, Raphael RA, Robinson RR, Nalawade S, Forsthuber TG. TNFR2 limits proinflammatory astrocyte functions during EAE induced by pathogenic DR2b-restricted T cells. Jci Insight. 4. PMID 31852844 DOI: 10.1172/Jci.Insight.132527  0.502
2019 Negron A, Robinson RR, Stüve O, Forsthuber TG. The role of B cells in multiple sclerosis: Current and future therapies. Cellular Immunology. 339: 10-23. PMID 31130183 DOI: 10.1016/J.Cellimm.2018.10.006  0.419
2018 Hung CY, Zhang H, Castro-Lopez N, Ostroff GR, Khoshlenar P, Abraham A, Cole GT, Negron A, Forsthuber T, Peng T, Galgiani JN, Ampel NM, Yu JJ. Glucan-chitin particles enhance Th17 response and improve protective efficacy of a multivalent antigen (rCpa1) against pulmonary infection. Infection and Immunity. PMID 30104216 DOI: 10.1128/Iai.00070-18  0.395
2018 Nalawade SA, Ji N, Raphael I, Pratt A, Kraig E, Forsthuber TG. Aire is not essential for regulating neuroinflammatory disease in mice transgenic for human autoimmune-diseases associated MHC class II genes HLA-DR2b and HLA-DR4. Cellular Immunology. PMID 29789121 DOI: 10.1016/J.Cellimm.2018.05.003  0.771
2018 Narayan RN, Forsthuber T, Stüve O. Emerging drugs for primary progressive multiple sclerosis. Expert Opinion On Emerging Drugs. 23: 97-110. PMID 29638150 DOI: 10.1080/14728214.2018.1463370  0.319
2018 Forsthuber TG, Cimbora DM, Ratchford JN, Katz E, Stüve O. B cell-based therapies in CNS autoimmunity: differentiating CD19 and CD20 as therapeutic targets. Therapeutic Advances in Neurological Disorders. 11: 1756286418761697. PMID 29593838 DOI: 10.1177/1756286418761697  0.382
2017 Shoemaker RH, Forsthuber TG. Targeting "Retired Antigens" for Cancer Immunoprevention. Cancer Prevention Research (Philadelphia, Pa.). 10: 607-608. PMID 29093010 DOI: 10.1158/1940-6207.Capr-17-0188  0.346
2017 Dubey D, Forsthuber T, Flanagan EP, Pittock SJ, Stüve O. B-cell-targeted therapies in relapsing forms of MS. Neurology(R) Neuroimmunology & Neuroinflammation. 4: e405. PMID 29082296 DOI: 10.1212/Nxi.0000000000000405  0.365
2017 Raphael I, Webb J, Gomez-Rivera F, Chase Huizar CA, Gupta R, Arulanandam BP, Wang Y, Haskins WE, Forsthuber TG. Serum Neuroinflammatory Disease-Induced Central Nervous System Proteins Predict Clinical Onset of Experimental Autoimmune Encephalomyelitis. Frontiers in Immunology. 8: 812. PMID 28769926 DOI: 10.3389/Fimmu.2017.00812  0.363
2016 Bloom J, Metz C, Nalawade S, Casabar J, Cheng KF, He M, Sherry B, Coleman T, Forsthuber T, Al-Abed Y. Identification of Iguratimod as an Inhibitor of Macrophage Migration Inhibitory Factor (MIF) with Steroid-Sparing Potential. The Journal of Biological Chemistry. PMID 27793992 DOI: 10.1074/Jbc.M116.743328  0.358
2016 Forsthuber TG, Stuve O. Targeting "bad" B cells in multiple sclerosis: Could laquinimod be part of the armamentarium? Neurology(R) Neuroimmunology & Neuroinflammation. 3: e283. PMID 27704037 DOI: 10.1212/Nxi.0000000000000283  0.514
2016 Cunningham AL, Guentzel MN, Yu JJ, Hung CY, Forsthuber TG, Navara CS, Yagita H, Williams IR, Klose KE, Eaves-Pyles TD, Arulanandam BP. M-Cells Contribute to the Entry of an Oral Vaccine but Are Not Essential for the Subsequent Induction of Protective Immunity against Francisella tularensis. Plos One. 11: e0153402. PMID 27100824 DOI: 10.1371/Journal.Pone.0153402  0.366
2016 Ketter P, Yu JJ, Cap AP, Forsthuber T, Arulanandam B. Pentraxin 3: An Immune Modulator of Infection and Useful Marker for Disease Severity Assessment in Sepsis. Expert Review of Clinical Immunology. PMID 26982005 DOI: 10.1586/1744666X.2016.1166957  0.339
2016 Ji N, Forsthuber TG. ELISPOT Techniques. Methods in Molecular Biology (Clifton, N.J.). 1304: 63-71. PMID 25117217 DOI: 10.1007/7651_2014_111  0.735
2015 Sosa RA, Murphey C, Robinson RR, Forsthuber TG. IFN-γ ameliorates autoimmune encephalomyelitis by limiting myelin lipid peroxidation. Proceedings of the National Academy of Sciences of the United States of America. 112: E5038-47. PMID 26305941 DOI: 10.1073/Pnas.1505955112  0.776
2015 Ji N, Kovalovsky A, Fingerle-Rowson G, Guentzel MN, Forsthuber TG. Macrophage migration inhibitory factor promotes resistance to glucocorticoid treatment in EAE. Neurology® Neuroimmunology & Neuroinflammation. 2: e139. PMID 26280015 DOI: 10.1212/Nxi.0000000000000139  0.726
2015 Latham LB, Lee MJ, Lincoln JA, Ji N, Forsthuber TG, Lindsey JW. Antivirus immune activity in multiple sclerosis correlates with MRI activity. Acta Neurologica Scandinavica. PMID 25939660 DOI: 10.1111/ane.12417  0.714
2015 Raphael I, Nalawade S, Eagar TN, Forsthuber TG. T cell subsets and their signature cytokines in autoimmune and inflammatory diseases. Cytokine. 74: 5-17. PMID 25458968 DOI: 10.1016/J.Cyto.2014.09.011  0.465
2014 Shetty A, Gupta SG, Varrin-Doyer M, Weber MS, Prod'homme T, Molnarfi N, Ji N, Nelson PA, Patarroyo JC, Schulze-Topphoff U, Fogal SE, Forsthuber T, Sobel RA, Bernard CC, Slavin AJ, et al. Immunodominant T-cell epitopes of MOG reside in its transmembrane and cytoplasmic domains in EAE. Neurology® Neuroimmunology & Neuroinflammation. 1: e22. PMID 25340074 DOI: 10.1212/Nxi.0000000000000022  0.755
2014 Varrin-Doyer M, Shetty A, Spencer CM, Schulze-Topphoff U, Weber MS, Bernard CC, Forsthuber T, Cree BA, Slavin AJ, Zamvil SS. MOG transmembrane and cytoplasmic domains contain highly stimulatory T-cell epitopes in MS. Neurology® Neuroimmunology & Neuroinflammation. 1: e20. PMID 25340072 DOI: 10.1212/Nxi.0000000000000020  0.447
2014 Stüve O, Warnke C, Deason K, Stangel M, Kieseier BC, Hartung HP, von Büdingen HC, Centonze D, Forsthuber TG, Knappertz V. CD19 as a molecular target in CNS autoimmunity. Acta Neuropathologica. 128: 177-90. PMID 24993505 DOI: 10.1007/S00401-014-1313-Z  0.491
2013 Sosa RA, Murphey C, Ji N, Cardona AE, Forsthuber TG. The kinetics of myelin antigen uptake by myeloid cells in the central nervous system during experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 191: 5848-57. PMID 24227784 DOI: 10.4049/Jimmunol.1300771  0.753
2013 Ji N, Somanaboeina A, Dixit A, Kawamura K, Hayward NJ, Self C, Olson GL, Forsthuber TG. Small molecule inhibitor of antigen binding and presentation by HLA-DR2b as a therapeutic strategy for the treatment of multiple sclerosis. Journal of Immunology (Baltimore, Md. : 1950). 191: 5074-84. PMID 24123687 DOI: 10.4049/Jimmunol.1300407  0.764
2013 Li W, Murthy AK, Lanka GK, Chetty SL, Yu JJ, Chambers JP, Zhong G, Forsthuber TG, Guentzel MN, Arulanandam BP. A T cell epitope-based vaccine protects against chlamydial infection in HLA-DR4 transgenic mice. Vaccine. 31: 5722-8. PMID 24096029 DOI: 10.1016/J.Vaccine.2013.09.036  0.497
2013 Garcia JA, Pino PA, Mizutani M, Cardona SM, Charo IF, Ransohoff RM, Forsthuber TG, Cardona AE. Regulation of adaptive immunity by the fractalkine receptor during autoimmune inflammation. Journal of Immunology (Baltimore, Md. : 1950). 191: 1063-72. PMID 23817416 DOI: 10.4049/Jimmunol.1300040  0.517
2013 Trivedi NH, Guentzel MN, Rodriguez AR, Yu JJ, Forsthuber TG, Arulanandam BP. Mast cells: multitalented facilitators of protection against bacterial pathogens. Expert Review of Clinical Immunology. 9: 129-38. PMID 23390944 DOI: 10.1586/Eci.12.95  0.402
2012 Mahesula S, Raphael I, Raghunathan R, Kalsaria K, Kotagiri V, Purkar AB, Anjanappa M, Shah D, Pericherla V, Jadhav YL, Gelfond JA, Forsthuber TG, Haskins WE. Immunoenrichment microwave and magnetic proteomics for quantifying CD47 in the experimental autoimmune encephalomyelitis model of multiple sclerosis. Electrophoresis. 33: 3820-9. PMID 23160929 DOI: 10.1002/Elps.201200515  0.367
2012 Arellano B, Hussain R, Zacharias T, Yoon J, David C, Zein S, Steinman L, Forsthuber T, Greenberg BM, Lambracht-Washington D, Ritchie AM, Bennett JL, Stüve O. Human aquaporin 4 281-300 is the immunodominant linear determinant in the context of HLA-DRB1*03:01: Relevance for diagnosing and monitoring patients with neuromyelitis optica Archives of Neurology. 69: 1125-1131. PMID 22751865 DOI: 10.1001/Archneurol.2012.1300  0.459
2012 Raphael I, Forsthuber TG. Stability of T-cell lineages in autoimmune diseases. Expert Review of Clinical Immunology. 8: 299-301. PMID 22607174 DOI: 10.1586/Eci.12.22  0.4
2012 Rodriguez AR, Yu JJ, Guentzel MN, Navara CS, Klose KE, Forsthuber TG, Chambers JP, Berton MT, Arulanandam BP. Mast cell TLR2 signaling is crucial for effective killing of Francisella tularensis. Journal of Immunology (Baltimore, Md. : 1950). 188: 5604-11. PMID 22529298 DOI: 10.4049/Jimmunol.1200039  0.364
2012 Shetty A, Gupta S, Weber M, Molnarfi N, Forsthuber T, Sobel R, Bernard C, Slavin A, Zamvil S. T Cell Epitope 119-132, but Not 35-55, Is the Immunodominant Encephalitogenic Determinant of the CNS Autoantigen, Myelin Oligodendrocyte Glycoprotein (P05.118) Neurology. 78: P05.118-P05.118. DOI: 10.1212/Wnl.78.1_Meetingabstracts.P05.118  0.483
2011 Sosa RA, Forsthuber TG. The critical role of antigen-presentation-induced cytokine crosstalk in the central nervous system in multiple sclerosis and experimental autoimmune encephalomyelitis. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 31: 753-68. PMID 21919736 DOI: 10.1089/Jir.2011.0052  0.78
2011 Thathiah P, Sanapala S, Rodriguez AR, Yu JJ, Murthy AK, Guentzel MN, Forsthuber TG, Chambers JP, Arulanandam BP. Non-FcεR bearing mast cells secrete sufficient interleukin-4 to control Francisella tularensis replication within macrophages. Cytokine. 55: 211-20. PMID 21565523 DOI: 10.1016/J.Cyto.2011.04.009  0.367
2011 Murthy AK, Li W, Chaganty BK, Kamalakaran S, Guentzel MN, Seshu J, Forsthuber TG, Zhong G, Arulanandam BP. Tumor necrosis factor alpha production from CD8+ T cells mediates oviduct pathological sequelae following primary genital Chlamydia muridarum infection. Infection and Immunity. 79: 2928-35. PMID 21536799 DOI: 10.1128/Iai.05022-11  0.41
2011 Ji N, Sosa RA, Forsthuber TG. More than just a T-box: the role of T-bet as a possible biomarker and therapeutic target in autoimmune diseases. Immunotherapy. 3: 435-41. PMID 21395384 DOI: 10.2217/Imt.10.111  0.776
2011 Ji N, Rao N, Guentzel NM, Arulanandam BP, Forsthuber TG. Anaphylaxis and mortality induced by treatment of mice with anti-VLA-4 antibody and pertussis toxin. Journal of Immunology (Baltimore, Md. : 1950). 186: 2750-6. PMID 21270409 DOI: 10.4049/Jimmunol.1000907  0.759
2011 Cantor JR, Yoo TH, Dixit A, Iverson BL, Forsthuber TG, Georgiou G. Therapeutic enzyme deimmunization by combinatorial T-cell epitope removal using neutral drift. Proceedings of the National Academy of Sciences of the United States of America. 108: 1272-7. PMID 21209329 DOI: 10.1073/Pnas.1014739108  0.4
2011 Murphey C, Chang S, Zhang X, Arulanandam B, Forsthuber TG. Induction of polyclonal CD8+ T cell activation and effector function by Pertussis toxin. Cellular Immunology. 267: 50-5. PMID 21130421 DOI: 10.1016/J.Cellimm.2010.11.003  0.704
2011 Rodriguez AR, Yu JJ, Murthy AK, Guentzel MN, Klose KE, Forsthuber TG, Chambers JP, Berton MT, Arulanandam BP. Mast cell/IL-4 control of Francisella tularensis replication and host cell death is associated with increased ATP production and phagosomal acidification. Mucosal Immunology. 4: 217-26. PMID 20861832 DOI: 10.1038/Mi.2010.59  0.349
2010 Li W, Murthy AK, Guentzel MN, Chambers JP, Forsthuber TG, Seshu J, Zhong G, Arulanandam BP. Immunization with a combination of integral chlamydial antigens and a defined secreted protein induces robust immunity against genital chlamydial challenge. Infection and Immunity. 78: 3942-9. PMID 20605976 DOI: 10.1128/Iai.00346-10  0.418
2010 Hofstetter HH, Forsthuber TG. Kinetics of IL-17- and interferon-gamma-producing PLPp-specific CD4 T cells in EAE induced by coinjection of PLPp/IFA with pertussis toxin in SJL mice. Neuroscience Letters. 476: 150-5. PMID 20398738 DOI: 10.1016/J.Neulet.2010.04.018  0.457
2010 Jupelli M, Selby DM, Guentzel MN, Chambers JP, Forsthuber TG, Zhong G, Murthy AK, Arulanandam BP. The contribution of interleukin-12/interferon-gamma axis in protection against neonatal pulmonary Chlamydia muridarum challenge. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 30: 407-15. PMID 20187773 DOI: 10.1089/Jir.2009.0083  0.357
2010 Yu JJ, Goluguri T, Guentzel MN, Chambers JP, Murthy AK, Klose KE, Forsthuber TG, Arulanandam BP. Francisella tularensis T-cell antigen identification using humanized HLA-DR4 transgenic mice. Clinical and Vaccine Immunology : Cvi. 17: 215-22. PMID 20016043 DOI: 10.1128/Cvi.00361-09  0.453
2009 Forsthuber TG, Muraro P. Is there a place for 'immuno' in the immunotherapy of multiple sclerosis? Immunotherapy. 1: 329-31. PMID 20635950 DOI: 10.2217/Imt.09.15  0.458
2008 Murphey CL, Forsthuber TG. Trends in HLA antibody screening and identification and their role in transplantation. Expert Review of Clinical Immunology. 4: 391-9. PMID 20476928 DOI: 10.1586/1744666X.4.3.391  0.667
2008 Kawamura K, McLaughlin KA, Weissert R, Forsthuber TG. Myelin-reactive type B T cells and T cells specific for low-affinity MHC-binding myelin peptides escape tolerance in HLA-DR transgenic mice. Journal of Immunology (Baltimore, Md. : 1950). 181: 3202-11. PMID 18713991 DOI: 10.4049/Jimmunol.181.5.3202  0.501
2008 Ketavarapu JM, Rodriguez AR, Yu JJ, Cong Y, Murthy AK, Forsthuber TG, Guentzel MN, Klose KE, Berton MT, Arulanandam BP. Mast cells inhibit intramacrophage Francisella tularensis replication via contact and secreted products including IL-4. Proceedings of the National Academy of Sciences of the United States of America. 105: 9313-8. PMID 18591675 DOI: 10.1073/Pnas.0707636105  0.373
2008 Li W, Murthy AK, Guentzel MN, Seshu J, Forsthuber TG, Zhong G, Arulanandam BP. Antigen-specific CD4+ T cells produce sufficient IFN-gamma to mediate robust protective immunity against genital Chlamydia muridarum infection. Journal of Immunology (Baltimore, Md. : 1950). 180: 3375-82. PMID 18292563 DOI: 10.4049/Jimmunol.180.5.3375  0.473
2008 Jane-wit D, Altuntas CZ, Monti J, Johnson JM, Forsthuber TG, Tuohy VK. Sex-defined T-cell responses to cardiac self determine differential outcomes of murine dilated cardiomyopathy. The American Journal of Pathology. 172: 11-21. PMID 18063702 DOI: 10.2353/Ajpath.2008.070324  0.342
2007 Forsthuber TG, Ji N. Quo vadis Th1 and Th2 cells in autoimmunity and infectious diseases: Th17 cells, the new kid on the block. Expert Review of Clinical Immunology. 3: 251-4. PMID 20477666 DOI: 10.1586/1744666X.3.3.251  0.739
2007 Hofstetter HH, Grau C, Buttmann M, Forsthuber TG, Gaupp S, Toyka KV, Gold R. The PLPp-specific T-cell population promoted by pertussis toxin is characterized by high frequencies of IL-17-producing cells. Cytokine. 40: 35-43. PMID 17881243 DOI: 10.1016/J.Cyto.2007.07.192  0.526
2007 Denkinger CM, Denkinger MD, Forsthuber TG. Pertussis toxin-induced cytokine differentiation and clonal expansion of T cells is mediated predominantly via costimulation. Cellular Immunology. 246: 46-54. PMID 17601518 DOI: 10.1016/J.Cellimm.2007.05.004  0.479
2007 Hofstetter HH, Kovalovsky A, Shive CL, Lehmann PV, Forsthuber TG. Neonatal induction of myelin-specific Th1/Th17 immunity does not result in experimental autoimmune encephalomyelitis and can protect against the disease in adulthood. Journal of Neuroimmunology. 187: 20-30. PMID 17482277 DOI: 10.1016/J.Jneuroim.2007.04.001  0.505
2006 Murthy AK, Cong Y, Murphey C, Guentzel MN, Forsthuber TG, Zhong G, Arulanandam BP. Chlamydial protease-like activity factor induces protective immunity against genital chlamydial infection in transgenic mice that express the human HLA-DR4 allele. Infection and Immunity. 74: 6722-9. PMID 17015458 DOI: 10.1128/Iai.01119-06  0.738
2006 Macaubas C, Wahlstrom J, Galvão da Silva AP, Forsthuber TG, Sønderstrup G, Kwok WW, DeKruyff RH, Umetsu DT. Allergen-specific MHC class II tetramer+ cells are detectable in allergic, but not in nonallergic, individuals. Journal of Immunology (Baltimore, Md. : 1950). 176: 5069-77. PMID 16585604 DOI: 10.4049/Jimmunol.176.8.5069  0.458
2006 Kort JJ, Kawamura K, Fugger L, Weissert R, Forsthuber TG. Efficient presentation of myelin oligodendrocyte glycoprotein peptides but not protein by astrocytes from HLA-DR2 and HLA-DR4 transgenic mice. Journal of Neuroimmunology. 173: 23-34. PMID 16386804 DOI: 10.1016/J.Jneuroim.2005.11.014  0.53
2006 Macaubas C, Wahlstrom J, Galvao da Silva AP, Forsthuber T, Sonderstrup G, Kwok W, DeKruyff R, Dale U. F.5. Allergen Specific Class II Tetramer Positive Cells in the Peripheral Blood of Allergic and Nonallergic Individuals Clinical Immunology. 119: S52. DOI: 10.1016/J.Clim.2006.04.045  0.302
2005 Hofstetter HH, Karulin AY, Forsthuber TG, Ott PA, Tary-Lehmann M, Lehmann PV. The cytokine signature of MOG-specific CD4 cells in the EAE of C57BL/6 mice. Journal of Neuroimmunology. 170: 105-14. PMID 16257061 DOI: 10.1016/J.Jneuroim.2005.09.004  0.455
2005 Nekrasova T, Shive C, Gao Y, Kawamura K, Guardia R, Landreth G, Forsthuber TG. ERK1-deficient mice show normal T cell effector function and are highly susceptible to experimental autoimmune encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 175: 2374-80. PMID 16081808 DOI: 10.4049/Jimmunol.175.4.2374  0.495
2005 Hofstetter HH, Targoni OS, Karulin AY, Forsthuber TG, Tary-Lehmann M, Lehmann PV. Does the frequency and avidity spectrum of the neuroantigen-specific T cells in the blood mirror the autoimmune process in the central nervous system of mice undergoing experimental allergic encephalomyelitis? Journal of Immunology (Baltimore, Md. : 1950). 174: 4598-605. PMID 15814682 DOI: 10.4049/Jimmunol.174.8.4598  0.522
2004 Klehmet J, Shive C, Guardia-Wolff R, Petersen I, Spack EG, Boehm BO, Weissert R, Forsthuber TG. T cell epitope spreading to myelin oligodendrocyte glycoprotein in HLA-DR4 transgenic mice during experimental autoimmune encephalomyelitis. Clinical Immunology (Orlando, Fla.). 111: 53-60. PMID 15093552 DOI: 10.1016/J.Clim.2003.12.012  0.492
2004 Denkinger M, Shive CL, Pantenburg B, Forsthuber TG. Suramin has adjuvant properties and promotes expansion of antigen-specific Th1 and Th2 cells in vivo. International Immunopharmacology. 4: 15-24. PMID 14975356 DOI: 10.1016/J.Intimp.2003.09.004  0.456
2003 Fingerle-Rowson G, Petrenko O, Metz CN, Forsthuber TG, Mitchell R, Huss R, Moll U, Müller W, Bucala R. The p53-dependent effects of macrophage migration inhibitory factor revealed by gene targeting. Proceedings of the National Academy of Sciences of the United States of America. 100: 9354-9. PMID 12878730 DOI: 10.1073/Pnas.1533295100  0.345
2003 Denkinger CM, Denkinger M, Kort JJ, Metz C, Forsthuber TG. In vivo blockade of macrophage migration inhibitory factor ameliorates acute experimental autoimmune encephalomyelitis by impairing the homing of encephalitogenic T cells to the central nervous system. Journal of Immunology (Baltimore, Md. : 1950). 170: 1274-82. PMID 12538686 DOI: 10.4049/Jimmunol.170.3.1274  0.529
2003 Hofstetter HH, Sewell DL, Liu F, Sandor M, Forsthuber T, Lehmann PV, Fabry Z. Autoreactive T cells promote post-traumatic healing in the central nervous system. Journal of Neuroimmunology. 134: 25-34. PMID 12507769 DOI: 10.1016/S0165-5728(02)00358-2  0.411
2002 Ebhardt MB, Shive CL, Guardia R, Gapin L, Boehm BO, Forsthuber TG. Immunological adjuvants efficiently induce antigen-specific T cell responses in old mice: implications for vaccine adjuvant development in aged individuals. Cellular Immunology. 215: 87-97. PMID 12142040 DOI: 10.1016/S0008-8749(02)00005-9  0.428
2002 Weissert R, Kuhle J, de Graaf KL, Wienhold W, Herrmann MM, Müller C, Forsthuber TG, Wiesmüller KH, Melms A. High immunogenicity of intracellular myelin oligodendrocyte glycoprotein epitopes. Journal of Immunology (Baltimore, Md. : 1950). 169: 548-56. PMID 12077287 DOI: 10.4049/Jimmunol.169.1.548  0.482
2002 Hofstetter HH, Shive CL, Forsthuber TG. Pertussis toxin modulates the immune response to neuroantigens injected in incomplete Freund's adjuvant: induction of Th1 cells and experimental autoimmune encephalomyelitis in the presence of high frequencies of Th2 cells. Journal of Immunology (Baltimore, Md. : 1950). 169: 117-25. PMID 12077236 DOI: 10.4049/Jimmunol.169.1.117  0.511
2001 Forsthuber TG, Shive CL, Wienhold W, de Graaf K, Spack EG, Sublett R, Melms A, Kort J, Racke MK, Weissert R. T cell epitopes of human myelin oligodendrocyte glycoprotein identified in HLA-DR4 (DRB1*0401) transgenic mice are encephalitogenic and are presented by human B cells. Journal of Immunology (Baltimore, Md. : 1950). 167: 7119-25. PMID 11739534 DOI: 10.4049/Jimmunol.167.12.7119  0.496
2001 Targoni OS, Baus J, Hofstetter HH, Hesse MD, Karulin AY, Boehm BO, Forsthuber TG, Lehmann PV. Frequencies of neuroantigen-specific T cells in the central nervous system versus the immune periphery during the course of experimental allergic encephalomyelitis. Journal of Immunology (Baltimore, Md. : 1950). 166: 4757-64. PMID 11254738 DOI: 10.4049/Jimmunol.166.7.4757  0.485
2000 Benson JM, Campbell KA, Guan Z, Gienapp IE, Stuckman SS, Forsthuber T, Whitacre CC. T-cell activation and receptor downmodulation precede deletion induced by mucosally administered antigen. The Journal of Clinical Investigation. 106: 1031-8. PMID 11032863 DOI: 10.1172/Jci10738  0.534
2000 Shive CL, Hofstetter H, Arredondo L, Shaw C, Forsthuber TG. The enhanced antigen-specific production of cytokines induced by pertussis toxin is due to clonal expansion of T cells and not to altered effector functions of long-term memory cells. European Journal of Immunology. 30: 2422-31. PMID 10940934 DOI: 10.1002/1521-4141(2000)30:8<2422::Aid-Immu2422>3.0.Co;2-H  0.469
2000 Lovett-Racke AE, Smith ME, Arredondo LR, Bittner PS, Ratts RB, Shive CL, Forsthuber TG, Racke MK. Developmentally regulated gene expression of Th2 cytokines in the brain Brain Research. 870: 27-35. PMID 10869498 DOI: 10.1016/S0006-8993(00)02398-2  0.395
2000 Heeger PS, Forsthuber T, Shive C, Biekert E, Genain C, Hofstetter HH, Karulin A, Lehmann PV. Revisiting tolerance induced by autoantigen in incomplete Freund's adjuvant. Journal of Immunology (Baltimore, Md. : 1950). 164: 5771-81. PMID 10820255 DOI: 10.4049/Jimmunol.164.11.5771  0.509
1998 Lehmann PV, Targoni OS, Forsthuber TG. Shifting T-cell activation thresholds in autoimmunity and determinant spreading. Immunological Reviews. 164: 53-61. PMID 9795763 DOI: 10.1111/J.1600-065X.1998.Tb01207.X  0.513
1998 Gross DM, Forsthuber T, Tary-Lehmann M, Etling C, Ito K, Nagy ZA, Field JA, Steere AC, Huber BT. Identification of LFA-1 as a candidate autoantigen in treatment-resistant Lyme arthritis. Science (New York, N.Y.). 281: 703-6. PMID 9685265 DOI: 10.1126/Science.281.5377.703  0.399
1998 Etling C, Forsthuber T. Pertussis toxin enhances differentiation and induces cytokine class switching of antigen-specific T cells Journal of Neuroimmunology. 90: 81. DOI: 10.1016/S0165-5728(98)91664-2  0.354
1996 Tian J, Atkinson MA, Clare-Salzler M, Herschenfeld A, Forsthuber T, Lehmann PV, Kaufman DL. Nasal administration of glutamate decarboxylase (GAD65) peptides induces Th2 responses and prevents murine insulin-dependent diabetes Journal of Experimental Medicine. 183: 1561-1567. PMID 8666914 DOI: 10.1084/Jem.183.4.1561  0.472
1996 Forsthuber T, Yip HC, Lehmann PV. Induction of TH1 and TH2 immunity in neonatal mice. Science (New York, N.Y.). 271: 1728-30. PMID 8596934 DOI: 10.1126/Science.271.5256.1728  0.426
1995 Forsthuber T, Cheng H, Karulin A, Lehmann P. Neonatal or adult injection of MBP in IFA induces a vigorous TH2-type T cell response** Journal of Neuroimmunology. 66-66. DOI: 10.1016/0165-5728(95)99089-2  0.4
1993 Kaufman DL, Clare-Salzler M, Tian J, Forsthuber T, Ting GS, Robinson P, Atkinson MA, Sercarz EE, Tobin AJ, Lehmann PV. Spontaneous loss of T-cell tolerance to glutamic acid decarboxylase in murine insulin-dependent diabetes. Nature. 366: 69-72. PMID 7694152 DOI: 10.1038/366069A0  0.44
1993 Lehmann PV, Sercarz EE, Forsthuber T, Dayan CM, Gammon G. Determinant spreading and the dynamics of the autoimmune T-cell repertoire. Immunology Today. 14: 203-8. PMID 7686009 DOI: 10.1016/0167-5699(93)90163-F  0.352
1993 Lehmann PV, Forsthuber T, Miller A, Sercarz EE. T cell responses to cryptic determinants of myelin basic protein are revealed after immunization with a dominant peptide of the molecule Journal of Neuroimmunology. 43: 209. DOI: 10.1016/0165-5728(93)90116-G  0.447
1992 Lehmann PV, Forsthuber T, Miller A, Sercarz EE. Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen. Nature. 358: 155-7. PMID 1377368 DOI: 10.1038/358155A0  0.547
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