| Year |
Citation |
Score |
| 2024 |
Waldherr SM, Han M, Saxton AD, Vadset TA, McMillan PJ, Wheeler JM, Liachko NF, Kraemer BC. Endoplasmic reticulum unfolded protein response transcriptional targets of XBP-1s mediate rescue from tauopathy. Communications Biology. 7: 903. PMID 39060347 DOI: 10.1038/s42003-024-06570-2 |
0.34 |
|
| 2023 |
Kow RL, Black AH, Henderson BP, Kraemer BC. Sut-6/NIPP1 modulates tau toxicity. Human Molecular Genetics. PMID 37000013 DOI: 10.1093/hmg/ddad049 |
0.382 |
|
| 2023 |
McMillan PJ, Benbow SJ, Uhrich R, Saxton A, Baum M, Strovas T, Wheeler JM, Baker J, Liachko NF, Keene CD, Latimer CS, Kraemer BC. Tau-RNA complexes inhibit microtubule polymerization and drive disease-relevant conformation change. Brain : a Journal of Neurology. PMID 36732296 DOI: 10.1093/brain/awad032 |
0.396 |
|
| 2022 |
Eck RJ, Kow RL, Black AH, Liachko NF, Kraemer BC. SPOP loss of function protects against tauopathy. Proceedings of the National Academy of Sciences of the United States of America. 120: e2207250120. PMID 36574656 DOI: 10.1073/pnas.2207250120 |
0.333 |
|
| 2022 |
Kow RL, Black AH, Saxton AD, Liachko NF, Kraemer BC. Loss of aly/ALYREF suppresses toxicity in both tau and TDP-43 models of neurodegeneration. Geroscience. PMID 35122183 DOI: 10.1007/s11357-022-00526-2 |
0.449 |
|
| 2021 |
McMillan PJ, Strovas TJ, Baum M, Mitchell BK, Eck RJ, Hendricks N, Wheeler JM, Latimer CS, Keene CD, Kraemer BC. Pathological tau drives ectopic nuclear speckle scaffold protein SRRM2 accumulation in neuron cytoplasm in Alzheimer's disease. Acta Neuropathologica Communications. 9: 117. PMID 34187600 DOI: 10.1186/s40478-021-01219-1 |
0.442 |
|
| 2020 |
Kow RL, Strovas TJ, McMillan PJ, Jacobi AM, Behlke MA, Saxton AD, Latimer CS, Keene CD, Kraemer BC. Distinct Poly(A) nucleases have differential impact on sut-2 dependent tauopathy phenotypes. Neurobiology of Disease. 147: 105148. PMID 33184027 DOI: 10.1016/j.nbd.2020.105148 |
0.386 |
|
| 2020 |
Baker JD, Uhrich RL, Strovas TJ, Saxton AD, Kraemer BC. AlphaScreen Identifies MSUT2 Inhibitors for Tauopathy-Targeting Therapeutic Discovery. Slas Discovery : Advancing Life Sciences R & D. 2472555220958387. PMID 32981422 DOI: 10.1177/2472555220958387 |
0.317 |
|
| 2020 |
Baker JD, Uhrich RL, Strovas TJ, Saxton AD, Kraemer BC. Targeting pathological tau by small molecule inhibition of the poly(A):MSUT2 RNA-protein interaction. Acs Chemical Neuroscience. PMID 32589834 DOI: 10.1021/acschemneuro.0c00214 |
0.472 |
|
| 2020 |
Lee EG, Tulloch J, Chen S, Leong L, Saxton AD, Kraemer B, Darvas M, Keene CD, Shutes-David A, Todd K, Millard S, Yu CE. Redefining transcriptional regulation of the APOE gene and its association with Alzheimer's disease. Plos One. 15: e0227667. PMID 31978088 DOI: 10.1371/Journal.Pone.0227667 |
0.328 |
|
| 2020 |
Baker JD, Kraemer BC. Inhibition of the MSUT2: RNA interaction for the treatment of tauopathies Alzheimer's & Dementia. 16. DOI: 10.1002/alz.047632 |
0.317 |
|
| 2019 |
Wheeler JM, McMillan P, Strovas TJ, Liachko NF, Amlie-Wolf A, Kow RL, Klein RL, Szot P, Robinson L, Guthrie C, Saxton A, Kanaan NM, Raskind M, Peskind E, Trojanowski JQ, ... ... Kraemer B, et al. Activity of the poly(A) binding protein MSUT2 determines susceptibility to pathological tau in the mammalian brain. Science Translational Medicine. 11. PMID 31852801 DOI: 10.1126/Scitranslmed.Aao6545 |
0.326 |
|
| 2019 |
Waldherr SM, Strovas TJ, Vadset TA, Liachko NF, Kraemer BC. Constitutive XBP-1s-mediated activation of the endoplasmic reticulum unfolded protein response protects against pathological tau. Nature Communications. 10: 4443. PMID 31570707 DOI: 10.1038/s41467-019-12070-3 |
0.382 |
|
| 2016 |
Guerrero EN, Wang H, Mitra J, Hegde PM, Stowell SE, Liachko NF, Kraemer BC, Garruto RM, Rao KS, Hegde ML. TDP-43/FUS in motor neuron disease: Complexity and challenges. Progress in Neurobiology. PMID 27693252 DOI: 10.1016/J.Pneurobio.2016.09.004 |
0.37 |
|
| 2016 |
Liachko NF, Saxton AD, McMillan PJ, Strovas TJ, Currey HN, Taylor LM, Wheeler JM, Oblak AL, Ghetti B, Montine TJ, Keene CD, Raskind MA, Bird TD, Kraemer BC. The phosphatase calcineurin regulates pathological TDP-43 phosphorylation. Acta Neuropathologica. PMID 27473149 DOI: 10.1007/S00401-016-1600-Y |
0.396 |
|
| 2015 |
Jablonski AM, Lamitina T, Liachko NF, Sabatella M, Lu J, Zhang L, Ostrow LW, Gupta P, Wu CY, Doshi S, Mojsilovic-Petrovic J, Lans H, Wang J, Kraemer B, Kalb RG. Loss of RAD-23 Protects Against Models of Motor Neuron Disease by Enhancing Mutant Protein Clearance. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 14286-306. PMID 26490867 DOI: 10.1523/Jneurosci.0642-15.2015 |
0.413 |
|
| 2015 |
Chen X, McCueF HV, Wong SQ, Kashyap SS, Kraemer BC, Barclay JW, Burgoyne RD, Morgan A. Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression. Molecular Neurodegeneration. 10: 51. PMID 26419537 DOI: 10.1186/S13024-015-0046-3 |
0.376 |
|
| 2014 |
Liachko NF, McMillan PJ, Strovas TJ, Loomis E, Greenup L, Murrell JR, Ghetti B, Raskind MA, Montine TJ, Bird TD, Leverenz JB, Kraemer BC. The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43. Plos Genetics. 10: e1004803. PMID 25473830 DOI: 10.1371/Journal.Pgen.1004803 |
0.348 |
|
| 2014 |
Salado IG, Redondo M, Bello ML, Perez C, Liachko NF, Kraemer BC, Miguel L, Lecourtois M, Gil C, Martinez A, Perez DI. Protein kinase CK-1 inhibitors as new potential drugs for amyotrophic lateral sclerosis. Journal of Medicinal Chemistry. 57: 2755-72. PMID 24592867 DOI: 10.1021/Jm500065F |
0.323 |
|
| 2013 |
Yu CE, Cudaback E, Foraker J, Thomson Z, Leong L, Lutz F, Gill JA, Saxton A, Kraemer B, Navas P, Keene CD, Montine T, Bekris LM. Epigenetic signature and enhancer activity of the human APOE gene. Human Molecular Genetics. 22: 5036-47. PMID 23892237 DOI: 10.1093/Hmg/Ddt354 |
0.334 |
|
| 2013 |
Korvatska O, Strand NS, Berndt JD, Strovas T, Chen DH, Leverenz JB, Kiianitsa K, Mata IF, Karakoc E, Greenup JL, Bonkowski E, Chuang J, Moon RT, Eichler EE, Nickerson DA, ... ... Kraemer BC, et al. Altered splicing of ATP6AP2 causes X-linked parkinsonism with spasticity (XPDS). Human Molecular Genetics. 22: 3259-68. PMID 23595882 DOI: 10.1093/Hmg/Ddt180 |
0.423 |
|
| 2013 |
Liachko NF, McMillan PJ, Guthrie CR, Bird TD, Leverenz JB, Kraemer BC. CDC7 inhibition blocks pathological TDP-43 phosphorylation and neurodegeneration. Annals of Neurology. 74: 39-52. PMID 23424178 DOI: 10.1002/Ana.23870 |
0.33 |
|
| 2013 |
McCormick AV, Wheeler JM, Guthrie CR, Liachko NF, Kraemer BC. Dopamine D2 receptor antagonism suppresses tau aggregation and neurotoxicity. Biological Psychiatry. 73: 464-71. PMID 23140663 DOI: 10.1016/J.Biopsych.2012.08.027 |
0.312 |
|
| 2013 |
Chen X, Kraemer B, Barclay J, Burgoyne R, Morgan A. Using Caenorhabditis elegans to fight human neurodegenerative diseases Molecular Neurodegeneration. 8: P12. DOI: 10.1186/1750-1326-8-S1-P12 |
0.355 |
|
| 2012 |
Watkins GR, Wang N, Mazalouskas MD, Gomez RJ, Guthrie CR, Kraemer BC, Schweiger S, Spiller BW, Wadzinski BE. Monoubiquitination promotes calpain cleavage of the protein phosphatase 2A (PP2A) regulatory subunit α4, altering PP2A stability and microtubule-associated protein phosphorylation. The Journal of Biological Chemistry. 287: 24207-15. PMID 22613722 DOI: 10.1074/Jbc.M112.368613 |
0.405 |
|
| 2012 |
Lim MA, Selak MA, Xiang Z, Krainc D, Neve RL, Kraemer BC, Watts JL, Kalb RG. Reduced activity of AMP-activated protein kinase protects against genetic models of motor neuron disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 1123-41. PMID 22262909 DOI: 10.1523/Jneurosci.6554-10.2012 |
0.355 |
|
| 2011 |
Guthrie CR, Kraemer BC. Proteasome inhibition drives HDAC6-dependent recruitment of tau to aggresomes Journal of Molecular Neuroscience. 45: 32-41. PMID 21340680 DOI: 10.1007/S12031-011-9502-X |
0.375 |
|
| 2010 |
Liachko NF, Guthrie CR, Kraemer BC. Phosphorylation promotes neurotoxicity in a Caenorhabditis elegans model of TDP-43 proteinopathy Journal of Neuroscience. 30: 16208-16219. PMID 21123567 DOI: 10.1523/Jneurosci.2911-10.2010 |
0.396 |
|
| 2010 |
Wheeler JM, Guthrie CR, Kraemer BC. The role of MSUT-2 in tau neurotoxicity: A target for neuroprotection in tauopathy? Biochemical Society Transactions. 38: 973-976. PMID 20658987 DOI: 10.1042/Bst0380973 |
0.325 |
|
| 2010 |
Kraemer BC, Schuck T, Wheeler JM, Robinson LC, Trojanowski JQ, Lee VM, Schellenberg GD. Loss of murine TDP-43 disrupts motor function and plays an essential role in embryogenesis. Acta Neuropathologica. 119: 409-19. PMID 20198480 DOI: 10.1007/S00401-010-0659-0 |
0.319 |
|
| 2009 |
Guthrie CR, Schellenberg GD, Kraemer BC. SUT-2 potentiates tau-induced neurotoxicity in Caenorhabditis elegans. Human Molecular Genetics. 18: 1825-38. PMID 19273536 DOI: 10.1093/Hmg/Ddp099 |
0.51 |
|
| 2007 |
Kraemer BC, Schellenberg GD. SUT-1 enables tau-induced neurotoxicity in C. elegans. Human Molecular Genetics. 16: 1959-71. PMID 17576746 DOI: 10.1093/Hmg/Ddm143 |
0.503 |
|
| 2007 |
MacMorris M, Kumar M, Lasda E, Larsen A, Kraemer B, Blumenthal T. A novel family of C. elegans snRNPs contains proteins associated with trans-splicing. Rna (New York, N.Y.). 13: 511-20. PMID 17283210 DOI: 10.1261/Rna.426707 |
0.578 |
|
| 2006 |
Kraemer BC, Burgess JK, Chen JH, Thomas JH, Schellenberg GD. Molecular pathways that influence human tau-induced pathology in Caenorhabditis elegans. Human Molecular Genetics. 15: 1483-96. PMID 16600994 DOI: 10.1093/Hmg/Ddl067 |
0.375 |
|
| 2006 |
Kraemer BC, McMillan P, Strovas TC, Keene D, Schellenberg GD, Wheeler JM. P2-171: THE POLY(A) BINDING PROTEIN MSUT2 MODULATES GLIOSIS IN TAUOPATHY Alzheimer's & Dementia. 14: P734-P734. DOI: 10.1016/J.Jalz.2018.06.858 |
0.315 |
|
| 2003 |
Kraemer BC, Zhang B, Leverenz JB, Thomas JH, Trojanowski JQ, Schellenberg GD. Neurodegeneration and defective neurotransmission in a Caenorhabditis elegans model of tauopathy. Proceedings of the National Academy of Sciences of the United States of America. 100: 9980-5. PMID 12872001 DOI: 10.1073/Pnas.1533448100 |
0.311 |
|
| 2002 |
Eckmann CR, Kraemer B, Wickens M, Kimble J. GLD-3, a bicaudal-C homolog that inhibits FBF to control germline sex determination in C. elegans. Developmental Cell. 3: 697-710. PMID 12431376 DOI: 10.1016/S1534-5807(02)00322-2 |
0.698 |
|
| 2000 |
Kraemer B, Zhang B, SenGupta D, Fields S, Wickens M. Using the yeast three-hybrid system to detect and analyze RNA-protein interactions. Methods in Enzymology. 328: 297-321. PMID 11075352 DOI: 10.1016/S0076-6879(00)28404-8 |
0.707 |
|
| 2000 |
Luitjens C, Gallegos M, Kraemer B, Kimble J, Wickens M. CPEB proteins control two key steps in spermatogenesis in C. elegans. Genes & Development. 14: 2596-609. PMID 11040214 DOI: 10.1101/Gad.831700 |
0.425 |
|
| 2000 |
Zhang B, Kraemer B, SenGupta D, Fields S, Wickens M. Yeast three-hybrid system to detect and analyze RNA-protein interactions. Methods in Enzymology. 318: 399-419. PMID 10890002 DOI: 10.1016/S0076-6879(00)18066-8 |
0.682 |
|
| 1999 |
Zhang B, Kraemer B, SenGupta D, Fields S, Wickens M. Yeast three-hybrid system to detect and analyze interactions between RNA and protein. Methods in Enzymology. 306: 93-113. PMID 10432449 DOI: 10.1016/S0076-6879(99)06007-3 |
0.71 |
|
| 1999 |
Lee Eg, Yeo A, Kraemer B, Wickens M, Linial ML. The gag domains required for avian retroviral RNA encapsidation determined by using two independent assays. Journal of Virology. 73: 6282-92. PMID 10400719 DOI: 10.1128/Jvi.73.8.6282-6292.1999 |
0.667 |
|
| 1996 |
SenGupta DJ, Zhang B, Kraemer B, Pochart P, Fields S, Wickens M. A three-hybrid system to detect RNA-protein interactions in vivo. Proceedings of the National Academy of Sciences of the United States of America. 93: 8496-501. PMID 8710898 DOI: 10.1073/Pnas.93.16.8496 |
0.716 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2024 |
Xu H, Qiu Q, Hu P, Hoxha K, Jang E, O'Reilly M, Kim C, He Z, Marotta N, Changolkar L, Zhang B, Wu H, Schellenberg GD, Kraemer B, Luk KC, et al. MSUT2 regulates tau spreading via adenosinergic signaling mediated ASAP1 pathway in neurons. Acta Neuropathologica. 147: 55. PMID 38472475 DOI: 10.1007/s00401-024-02703-3 |
0.289 |
|
| 2014 |
Boyd JD, Lee-Armandt JP, Feiler MS, Zaarur N, Liu M, Kraemer B, Concannon JB, Ebata A, Wolozin B, Glicksman MA. A high-content screen identifies novel compounds that inhibit stress-induced TDP-43 cellular aggregation and associated cytotoxicity. Journal of Biomolecular Screening. 19: 44-56. PMID 24019256 DOI: 10.1177/1087057113501553 |
0.284 |
|
| 2020 |
McMillan P, Wheeler J, Gatlin RE, Taylor L, Strovas T, Baum M, Bird TD, Latimer C, Keene CD, Kraemer BC, Liachko NF. Adult onset pan-neuronal human tau tubulin kinase 1 expression causes severe cerebellar neurodegeneration in mice. Acta Neuropathologica Communications. 8: 200. PMID 33228809 DOI: 10.1186/s40478-020-01073-7 |
0.273 |
|
| 2019 |
Liachko NF, Saxton AD, McMillan PJ, Strovas TJ, Keene CD, Bird TD, Kraemer BC. Genome wide analysis reveals heparan sulfate epimerase modulates TDP-43 proteinopathy. Plos Genetics. 15: e1008526. PMID 31834878 DOI: 10.1371/Journal.Pgen.1008526 |
0.268 |
|
| 2024 |
Riordan R, Saxton A, Han M, McMillan PJ, Kow RL, Liachko NF, Kraemer BC. TMEM106B C-terminal fragments aggregate and drive neurodegenerative proteinopathy in transgenic Caenorhabditis elegans. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 39711302 DOI: 10.1002/alz.14468 |
0.266 |
|
| 2020 |
Rojas-Prats E, Martinez-Gonzalez L, Gonzalo-Consuegra C, Liachko NF, Perez C, Ramírez D, Kraemer BC, Martin-Requero Á, Perez DI, Gil C, de Lago E, Martinez A. Targeting nuclear protein TDP-43 by cell division cycle kinase 7 inhibitors: A new therapeutic approach for amyotrophic lateral sclerosis. European Journal of Medicinal Chemistry. 112968. PMID 33139113 DOI: 10.1016/j.ejmech.2020.112968 |
0.263 |
|
| 2016 |
Meabon JS, Huber BR, Cross DJ, Richards TL, Minoshima S, Pagulayan KF, Li G, Meeker KD, Kraemer BC, Petrie EC, Raskind MA, Peskind ER, Cook DG. Repetitive blast exposure in mice and combat veterans causes persistent cerebellar dysfunction. Science Translational Medicine. 8: 321ra6. PMID 26764157 DOI: 10.1126/Scitranslmed.Aaa9585 |
0.253 |
|
| 2011 |
Guthrie CR, Greenup L, Leverenz JB, Kraemer BC. MSUT2 is a determinant of susceptibility to tau neurotoxicity Human Molecular Genetics. 20: 1989-1999. PMID 21355046 DOI: 10.1093/hmg/ddr079 |
0.251 |
|
| 2013 |
Huber BR, Meabon JS, Martin TJ, Mourad PD, Bennett R, Kraemer BC, Cernak I, Petrie EC, Emery MJ, Swenson ER, Mayer C, Mehic E, Peskind ER, Cook DG. Blast exposure causes early and persistent aberrant phospho- and cleaved-tau expression in a murine model of mild blast-induced traumatic brain injury. Journal of Alzheimer's Disease : Jad. 37: 309-23. PMID 23948882 DOI: 10.3233/Jad-130182 |
0.249 |
|
| 2021 |
Saxton AD, Kraemer BC. Human Ubiquilin 2 and TDP-43 co-pathology drives neurodegeneration in transgenic C. elegans. G3 (Bethesda, Md.). PMID 33963840 DOI: 10.1093/g3journal/jkab158 |
0.248 |
|
| 2012 |
Wheeler JM, Guthrie CR, Kraemer BC. Potential neuroprotective strategies against tauopathy Biochemical Society Transactions. 40: 656-660. PMID 22817711 DOI: 10.1042/Bst20120017 |
0.248 |
|
| 2024 |
Han M, Saxton A, Currey H, Waldherr SM, Liachko NF, Kraemer BC. Transgenic Dendra2::tau expression allows in vivo monitoring of tau proteostasis in C. elegans. Disease Models & Mechanisms. PMID 38469687 DOI: 10.1242/dmm.050473 |
0.248 |
|
| 2024 |
Stanley TR, Otero EM, Knight AL, Saxton AD, Ding X, Borgen M, Kraemer BC, Kim Guisbert KS, Guisbert E. Activation of the heat shock response as a therapeutic strategy for tau toxicity. Disease Models & Mechanisms. 17. PMID 39352120 DOI: 10.1242/dmm.050635 |
0.245 |
|
| 2016 |
Huber BR, Meabon JS, Hoffer ZS, Zhang J, Hoekstra JG, Pagulayan KF, McMillan PJ, Mayer CL, Banks WA, Kraemer BC, Raskind MA, McGavern DB, Peskind ER, Cook DG. Blast Exposure Causes Dynamic Microglial/Macrophage Responses and Microdomains of Brain Microvessel Dysfunction. Neuroscience. PMID 26777891 DOI: 10.1016/J.Neuroscience.2016.01.022 |
0.239 |
|
| 2011 |
Wang DB, Gitcho MA, Kraemer BC, Klein RL. Genetic strategies to study TDP-43 in rodents and to develop preclinical therapeutics for amyotrophic lateral sclerosis. The European Journal of Neuroscience. 34: 1179-88. PMID 21777407 DOI: 10.1111/j.1460-9568.2011.07803.x |
0.227 |
|
| 2020 |
Benbow SJ, Strovas TJ, Darvas M, Saxton A, Kraemer BC. Synergistic toxicity between tau and amyloid drives neuronal dysfunction and neurodegeneration in transgenic C. elegans. Human Molecular Genetics. PMID 31943011 DOI: 10.1093/Hmg/Ddz319 |
0.217 |
|
| 2019 |
Mitra J, Guerrero EN, Hegde PM, Liachko NF, Wang H, Vasquez V, Gao J, Pandey A, Taylor JP, Kraemer BC, Wu P, Boldogh I, Garruto RM, Mitra S, Rao KS, et al. Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects. Proceedings of the National Academy of Sciences of the United States of America. PMID 30770445 DOI: 10.1073/Pnas.1818415116 |
0.201 |
|
| 2024 |
Jadhav VS, Stair JG, Eck RJ, Smukowski SN, Currey HN, Toscano LG, Hincks JC, Latimer CS, Valdmanis PN, Kraemer BC, Liachko NF. Transcriptomic evaluation of tau and TDP-43 synergism shows tauopathy predominance and reveals potential modulating targets. Neurobiology of Disease. 193: 106441. PMID 38378122 DOI: 10.1016/j.nbd.2024.106441 |
0.195 |
|
| 2017 |
Kow RL, Sikkema C, Wheeler JM, Wilkinson CW, Kraemer BC. Dopa Decarboxylase Modulates Tau Toxicity. Biological Psychiatry. PMID 28751068 DOI: 10.1016/J.Biopsych.2017.06.007 |
0.191 |
|
| 2018 |
Wong SQ, Pontifex MG, Phelan MM, Pidathala C, Kraemer BC, Barclay JW, Berry NG, O'Neill PM, Burgoyne RD, Morgan A. α-Methyl-α-phenylsuccinimide ameliorates neurodegeneration in a C. elegans model of TDP-43 proteinopathy. Neurobiology of Disease. PMID 29940336 DOI: 10.1016/J.Nbd.2018.06.013 |
0.188 |
|
| 2023 |
Currey HN, Kraemer BC, Liachko NF. loss of function mutants protect against tau-driven shortened lifespan and hyperactive pharyngeal pumping in a model of tau toxicity. Micropublication Biology. 2023. PMID 37602280 DOI: 10.17912/micropub.biology.000844 |
0.183 |
|
| 2022 |
Latimer CS, Stair JG, Hincks JC, Currey HN, Bird TD, Keene CD, Kraemer BC, Liachko NF. TDP-43 promotes tau accumulation and selective neurotoxicity in bigenic C. elegans. Disease Models & Mechanisms. PMID 35178571 DOI: 10.1242/dmm.049323 |
0.183 |
|
| 2018 |
Taylor LM, McMillan PJ, Liachko NF, Strovas TJ, Ghetti B, Bird TD, Dirk Keene C, Kraemer BC. Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration. Molecular Neurodegeneration. 13: 7. PMID 29409526 DOI: 10.1186/S13024-018-0237-9 |
0.176 |
|
| 2015 |
Wheeler JM, McMillan PJ, Hawk M, Iba M, Robinson L, Xu GJ, Dombroski BA, Jeong D, Dichter MA, Juul H, Loomis E, Raskind M, Leverenz JB, Trojanowski JQ, Lee VM, ... ... Kraemer BC, et al. High copy wildtype human 1N4R tau expression promotes early pathological tauopathy accompanied by cognitive deficits without progressive neurofibrillary degeneration. Acta Neuropathologica Communications. 3: 33. PMID 26041339 DOI: 10.1186/S40478-015-0210-6 |
0.171 |
|
| 2011 |
McMillan PJ, Kraemer BC, Robinson L, Leverenz JB, Raskind M, Schellenberg G. Truncation of tau at E391 promotes early pathologic changes in transgenic mice. Journal of Neuropathology and Experimental Neurology. 70: 1006-19. PMID 22002427 DOI: 10.1097/Nen.0B013E31823557Fb |
0.163 |
|
| 2021 |
Eck RJ, Kraemer BC, Liachko NF. Regulation of TDP-43 phosphorylation in aging and disease. Geroscience. PMID 34032984 DOI: 10.1007/s11357-021-00383-5 |
0.154 |
|
| 2024 |
Logsdon AF, Foresi B, Hu SJ, Quah E, Meuret CJ, Le JP, Hendrickson AS, Redford IK, Kumar A, Phan BA, Doan TP, Noonan C, Hendricks NE, Wheeler JM, Kraemer BC, et al. Perineuronal net deglycosylation associates with tauopathy-induced gliosis and neurodegeneration. Journal of Neurochemistry. PMID 38317026 DOI: 10.1111/jnc.16067 |
0.151 |
|
| 2024 |
Eck RJ, Stair JG, Kraemer BC, Liachko NF. Simple models to understand complex disease: 10 years of progress from models of amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Frontiers in Neuroscience. 17: 1300705. PMID 38239833 DOI: 10.3389/fnins.2023.1300705 |
0.15 |
|
| 2024 |
Riordan R, Saxton A, McMillan PJ, Kow RL, Liachko NF, Kraemer BC. TMEM106B C-terminal fragments aggregate and drive neurodegenerative proteinopathy. Biorxiv : the Preprint Server For Biology. PMID 38915598 DOI: 10.1101/2024.06.11.598478 |
0.144 |
|
| 2021 |
Latimer CS, Keene CD, Kraemer BC, Liachko NF. TDP-43 promotes pathological tau phosphorylation and selective neurotoxicity in C. elegans. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 17: e058137. PMID 34971207 DOI: 10.1002/alz.058137 |
0.136 |
|
| 2007 |
Kraemer B, Schellenberg GD. Using Caenorhabditis elegans models of neurodegenerative disease to identify neuroprotective strategies. International Review of Neurobiology. 77: 219-46. PMID 17178476 DOI: 10.1016/S0074-7742(06)77007-6 |
0.135 |
|
| 2019 |
Latimer CS, Burke BT, Liachko NF, Currey HN, Kilgore MD, Gibbons LE, Henriksen J, Darvas M, Domoto-Reilly K, Jayadev S, Grabowski TJ, Crane PK, Larson EB, Kraemer BC, Bird TD, et al. Resistance and resilience to Alzheimer's disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort. Acta Neuropathologica Communications. 7: 9. PMID 31174609 DOI: 10.1186/S40478-019-0743-1 |
0.135 |
|
| 2019 |
Taylor LM, McMillan PJ, Kraemer BC, Liachko NF. Tau tubulin kinases in proteinopathy. The Febs Journal. PMID 31034749 DOI: 10.1111/febs.14866 |
0.13 |
|
| 2020 |
Benbow SJ, Strovas TJ, Darvas M, Saxton A, Kraemer BC. Synergistic toxicity between tau and amyloid drives neuronal dysfunction and neurodegeneration in transgenic
Caenorhabditis elegans Alzheimer's & Dementia. 16. DOI: 10.1002/alz.047426 |
0.13 |
|
| 2014 |
Dohi K, Kraemer BC, Erickson MA, McMillan PJ, Kovac A, Flachbartova Z, Hansen KM, Shah GN, Sheibani N, Salameh T, Banks WA. Molecular hydrogen in drinking water protects against neurodegenerative changes induced by traumatic brain injury. Plos One. 9: e108034. PMID 25251220 DOI: 10.1371/Journal.Pone.0108034 |
0.125 |
|
| 2016 |
Keene CD, Darvas M, Kraemer B, Liggitt D, Sigurdson C, Ladiges W. Neuropathological assessment and validation of mouse models for Alzheimer's disease: applying NIA-AA guidelines. Pathobiology of Aging & Age Related Diseases. 6: 32397. PMID 27317189 |
0.122 |
|
| 2015 |
Kraemer BC, Strovas TC, Liachko N, McMillan P. Tau tubulin kinases promote proteinopathy in both ftld-tau and FTLD-TDP-43 Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.07.164 |
0.121 |
|
| 2025 |
Eck RJ, Valdmanis PN, Liachko NF, Kraemer BC. Alternative 3' UTR polyadenylation is disrupted in the rNLS8 mouse model of ALS/FTLD. Molecular Brain. 18: 1. PMID 39810199 DOI: 10.1186/s13041-025-01174-1 |
0.12 |
|
| 2010 |
Kraemer BC, Guthrie CR, Liachko NR, Wheeler JM. O1-04-05: TDP-43 loss of function and gain of toxic function mutations cause motor dysfunction in animal models Alzheimer's & Dementia. 6: S77-S77. DOI: 10.1016/J.Jalz.2010.05.229 |
0.114 |
|
| 2020 |
Reed M, Kraemer B. Decision letter: Alzheimer’s disease risk gene BIN1 induces Tau-dependent network hyperexcitability Elife. DOI: 10.7554/Elife.57354.Sa1 |
0.112 |
|
| 2016 |
Taylor L, McMillan P, Liachko N, Strovas TC, Kraemer BC. Tau Tubulin Kinase Activation Coincides With Neuropathology In Dementia Alzheimers & Dementia. 12: 392. DOI: 10.1016/J.Jalz.2016.06.740 |
0.11 |
|
| 2018 |
Weeks JC, Roberts WM, Leasure C, Suzuki BM, Robinson KJ, Currey H, Wangchuk P, Eichenberger RM, Saxton AD, Bird TD, Kraemer BC, Loukas A, Hawdon JM, Caffrey CR, Liachko NF. Sertraline, Paroxetine, and Chlorpromazine Are Rapidly Acting Anthelmintic Drugs Capable of Clinical Repurposing. Scientific Reports. 8: 975. PMID 29343694 DOI: 10.1038/S41598-017-18457-W |
0.108 |
|
| 2004 |
Kraemer BC, Thomas JH, Schellenberg GD. O1-04-02 Genetic modifiers of pathological TAU in Caenorhabidits elegans Neurobiology of Aging. 25: S16-S17. DOI: 10.1016/S0197-4580(04)80053-8 |
0.087 |
|
| 2021 |
Baker JD, Uhrich RL, Kraemer GC, Love JE, Kraemer BC. A drug repurposing screen identifies hepatitis C antivirals as inhibitors of the SARS-CoV2 main protease. Plos One. 16: e0245962. PMID 33524017 DOI: 10.1371/journal.pone.0245962 |
0.086 |
|
| 2019 |
Urfer SR, Latimer CS, Ladiges W, Keene CD, Benbow S, Harrison B, Promislow DEL, Kaeberlein M, Kraemer BC, Wang A, Guscetti F, Darvas M. Cross species application of quantitative neuropathology assays developed for clinical Alzheimer's disease samples. Pathobiology of Aging & Age Related Diseases. 9: 1657768. PMID 31528297 DOI: 10.1080/20010001.2019.1657768 |
0.082 |
|
| 2015 |
Chen X, McCue HV, Wong SQ, Kashyap SS, Kraemer BC, Barclay JW, Burgoyne RD, Morgan A. Erratum to: Ethosuximide ameliorates neurodegenerative disease phenotypes by modulating DAF-16/FOXO target gene expression. Molecular Neurodegeneration. 10: 54. PMID 26496836 DOI: 10.1186/s13024-015-0051-6 |
0.077 |
|
| 2008 |
Kraemer BC. P1-024: Loss of SUT-2 prevents Tau neurotoxicity Alzheimer's & Dementia. 4: T212-T212. DOI: 10.1016/j.jalz.2008.05.609 |
0.072 |
|
| 2013 |
Huber BR, Meabon J, Mourad P, Bennett R, Kraemer B, Cernak I, Swenson E, Mayer C, Petrie E, Cook D, Peskind E. O1-07-03: Mild blast exposure induces early and persistent aberrant phospho- and cleaved tau expression in mice Alzheimer's & Dementia. 9: P141-P141. DOI: 10.1016/J.Jalz.2013.04.088 |
0.07 |
|
| 2016 |
Liachko N, Saxton A, Strovas TC, McMillan P, Kraemer BC. P4-089: Calcineurin Protects Against Pathological TDP-43 Accumulation in Frontotemporal Lobar Degeneration Alzheimer's & Dementia. 12: P1046-P1046. DOI: 10.1016/j.jalz.2016.06.2178 |
0.068 |
|
| 2019 |
Sillitoe RV, Schneider-Maunoury S, Kraemer B. Decision letter: TTBK2 and primary cilia are essential for the connectivity and survival of cerebellar Purkinje neurons Elife. DOI: 10.7554/Elife.51166.Sa1 |
0.067 |
|
| 2012 |
Kraemer B, Guthrie C, Wheeler J. O1-07-04: Identifying protective strategies against tau neurotoxicity Alzheimer's & Dementia. 8: P97-P98. DOI: 10.1016/J.Jalz.2012.05.242 |
0.062 |
|
| 2010 |
Kraemer B, Guthrie C, Leverenz J. P1-150: Tau neurotoxicity and MSUT2 Alzheimer's & Dementia. 6: S217-S217. DOI: 10.1016/j.jalz.2010.05.699 |
0.059 |
|
| 2012 |
Anisimov VN, Bartke A, Barzilai N, Batin MA, Blagosklonny MV, Brown-Borg H, Budovskaya Y, Campisi J, Friguet B, Fraifeld V, Franceschi C, Gems D, Gladyshev V, Gorbunova V, Gudkov AV, ... ... Kraemer B, et al. The second international conference "genetics of aging and longevity". Aging. 4: 305-17. PMID 22661237 |
0.05 |
|
| 2015 |
Peskind ER, Kraemer B, Zhang J. Biofluid Biomarkers of Mild Traumatic Brain Injury: Whither Plasma Tau. Jama Neurology. PMID 26237033 DOI: 10.1001/jamaneurol.2015.1789 |
0.048 |
|
| 2015 |
Peskind ER, Kraemer B, Zhang J. Biofluid biomarkers of mild traumatic brain injury Jama Neurology. 72: 1103-1105. PMID 26237199 DOI: 10.1001/Jamaneurol.2015.1743 |
0.023 |
|
| 2017 |
Kraemer BC, Schellenberg GD, Wheeler J, Dirk Keene C, McMillan P, Strovas TC. [O2-18-05]: PREVENTING TAUOPATHY BY TARGETING MSUT2 Alzheimer's & Dementia. 13: P604-P604. DOI: 10.1016/J.Jalz.2017.07.251 |
0.021 |
|
| 2014 |
Dohi K, Kovac A, Erickson M, Kraemer BC, Ogawa T, Banks WA. Hydrogen in Drinking Water Reduces Brain Edema after Traumatic Brain Injury in Mice Free Radical Biology and Medicine. 76: S22. DOI: 10.1016/j.freeradbiomed.2014.10.471 |
0.016 |
|
| 2006 |
Kraemer BC, Thomas JH, Schellenberg GD. O2-04-08 Alzheimers & Dementia. 2. DOI: 10.1016/J.Jalz.2006.05.136 |
0.01 |
|
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