| Year |
Citation |
Score |
| 2010 |
Yang XF, Schmidt BF, Rode DL, Rothman SM. Optical suppression of experimental seizures in rat brain slices. Epilepsia. 51: 127-35. PMID 19674053 DOI: 10.1111/j.1528-1167.2009.02252.x |
0.323 |
|
| 2008 |
Xu L, Rensing N, Yang XF, Zhang HX, Thio LL, Rothman SM, Weisenfeld AE, Wong M, Yamada KA. Leptin inhibits 4-aminopyridine- and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents. The Journal of Clinical Investigation. 118: 272-80. PMID 18097472 DOI: 10.1172/JCI33009 |
0.305 |
|
| 2007 |
Zeng LH, Xu L, Rensing NR, Sinatra PM, Rothman SM, Wong M. Kainate seizures cause acute dendritic injury and actin depolymerization in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11604-13. PMID 17959803 DOI: 10.1523/JNEUROSCI.0983-07.2007 |
0.35 |
|
| 2007 |
Rothman SM, Perry G, Yang XF, Hyrc K, Schmidt BF. Optical suppression of seizure-like activity with an LED. Epilepsy Research. 74: 201-9. PMID 17448638 DOI: 10.1016/j.eplepsyres.2007.03.009 |
0.326 |
|
| 2006 |
Yang XF, Kennedy BR, Lomber SG, Schmidt RE, Rothman SM. Cooling produces minimal neuropathology in neocortex and hippocampus. Neurobiology of Disease. 23: 637-43. PMID 16828292 DOI: 10.1016/J.Nbd.2006.05.006 |
0.307 |
|
| 2006 |
Griffey MA, Wozniak D, Wong M, Bible E, Johnson K, Rothman SM, Wentz AE, Cooper JD, Sands MS. CNS-directed AAV2-mediated gene therapy ameliorates functional deficits in a murine model of infantile neuronal ceroid lipofuscinosis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 538-47. PMID 16364693 DOI: 10.1016/J.Ymthe.2005.11.008 |
0.321 |
|
| 2005 |
Burton JM, Peebles GA, Binder DK, Rothman SM, Smyth MD. Transcortical cooling inhibits hippocampal-kindled seizures in the rat. Epilepsia. 46: 1881-7. PMID 16393153 DOI: 10.1111/j.1528-1167.2005.00299.x |
0.313 |
|
| 2005 |
Yang XF, Ouyang Y, Kennedy BR, Rothman SM. Cooling blocks rat hippocampal neurotransmission by a presynaptic mechanism: observations using 2-photon microscopy. The Journal of Physiology. 567: 215-24. PMID 15961429 DOI: 10.1113/jphysiol.2005.088948 |
0.329 |
|
| 2004 |
Chang JH, Yang XF, Zempel JM, Rothman SM. The unilateral cobalt wire model of neocortical epilepsy: a method of producing subacute focal seizures in rodents. Epilepsy Research. 61: 153-60. PMID 15451016 DOI: 10.1016/j.eplepsyres.2004.07.012 |
0.307 |
|
| 2004 |
Griffey M, Wozniak D, Wong M, Rothman S, Bible E, Cooper J, Vogler C, Sands M. AAV-mediated gene therapy causes functional improvements in a murine model of infantile neuronal ceroid lipofuscinosis (INCL, Batten disease) Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.05.065 |
0.309 |
|
| 2003 |
Yang XF, Chang JH, Rothman SM. Long-lasting anticonvulsant effect of focal cooling on experimental neocortical seizures. Epilepsia. 44: 1500-5. PMID 14636319 DOI: 10.1111/j.0013-9580.2003.23003.x |
0.317 |
|
| 2002 |
Xia S, Cai ZY, Thio LL, Kim-Han JS, Dugan LL, Covey DF, Rothman SM. The estrogen receptor is not essential for all estrogen neuroprotection: new evidence from a new analog. Neurobiology of Disease. 9: 282-93. PMID 11950274 DOI: 10.1006/Nbdi.2002.0478 |
0.361 |
|
| 2001 |
Yang XF, Rothman SM. Focal cooling rapidly terminates experimental neocortical seizures. Annals of Neurology. 49: 721-6. PMID 11409423 DOI: 10.1002/ana.1021 |
0.321 |
|
| 2000 |
Hill MW, Wong M, Amarakone A, Rothman SM. Rapid cooling aborts seizure-like activity in rodent hippocampal-entorhinal slices. Epilepsia. 41: 1241-8. PMID 11051118 DOI: 10.1111/J.1528-1157.2000.Tb04601.X |
0.315 |
|
| 2000 |
Werth JL, Deshmukh M, Cocabo J, Johnson EM, Rothman SM. Reversible physiological alterations in sympathetic neurons deprived of NGF but protected from apoptosis by caspase inhibition or Bax deletion. Experimental Neurology. 161: 203-11. PMID 10683286 DOI: 10.1006/Exnr.1999.7241 |
0.315 |
|
| 1999 |
Hill MW, de la Cruz MA, Covey DF, Rothman SM. Effects of anticonvulsant lactams on in vitro seizures in the hippocampal slice preparation. Epilepsy Research. 37: 121-31. PMID 10510978 DOI: 10.1016/S0920-1211(99)00041-8 |
0.454 |
|
| 1998 |
Hill MW, Reddy PA, Covey DF, Rothman SM. Contribution of subsaturating GABA concentrations to IPSCs in cultured hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5103-11. PMID 9651194 |
0.322 |
|
| 1998 |
Hill MW, Reddy PA, Covey DF, Rothman SM. Inhibition of voltage-dependent sodium channels by the anticonvulsant gamma-aminobutyric acid type A receptor modulator, 3-benzyl-3-ethyl-2-piperidinone. The Journal of Pharmacology and Experimental Therapeutics. 285: 1303-9. PMID 9618437 |
0.337 |
|
| 1998 |
Werth JL, Park TS, Silbergeld DL, Rothman SM. Excitotoxic swelling occurs in oxygen and glucose deprived human cortical slices. Brain Research. 782: 248-54. PMID 9519270 DOI: 10.1016/S0006-8993(97)01286-9 |
0.374 |
|
| 1998 |
Canney DJ, Lu HF, McKeon AC, Yoon KW, Xu K, Holland KD, Rothman SM, Ferrendelli JA, Covey DF. Structure-activity studies of fluoroalkyl-substituted gamma-butyrolactone and gamma-thiobutyrolactone modulators of GABA(A) receptor function. Bioorganic & Medicinal Chemistry. 6: 43-55. PMID 9502104 DOI: 10.1016/S0968-0896(97)10006-2 |
0.549 |
|
| 1998 |
Hill MW, Reddy PA, Covey DF, Rothman SM. Contribution of Subsaturating GABA Concentrations to IPSCs in Cultured Hippocampal Neurons The Journal of Neuroscience. 18: 5103-5111. DOI: 10.1523/Jneurosci.18-14-05103.1998 |
0.318 |
|
| 1997 |
Hyrc K, Handran SD, Rothman SM, Goldberg MP. Ionized intracellular calcium concentration predicts excitotoxic neuronal death: observations with low-affinity fluorescent calcium indicators. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 6669-77. PMID 9254679 DOI: 10.1523/Jneurosci.17-17-06669.1997 |
0.319 |
|
| 1997 |
Williams KL, Tucker JB, White G, Weiss DS, Ferrendelli JA, Covey DF, Krause JE, Rothman SM. Lactone modulation of the gamma-aminobutyric acid A receptor: evidence for a positive modulatory site. Molecular Pharmacology. 52: 114-9. PMID 9224820 DOI: 10.1124/Mol.52.1.114 |
0.412 |
|
| 1997 |
Reddy PA, Woodward KE, McIlheran SM, Hsiang BC, Latifi TN, Hill MW, Rothman SM, Ferrendelli JA, Covey DF. Synthesis and anticonvulsant activities of 3,3-dialkyl- and 3-alkyl-3-benzyl-2-piperidinones (delta-valerolactams) and hexahydro-2H-azepin-2-ones (epsilon-caprolactams). Journal of Medicinal Chemistry. 40: 44-9. PMID 9016327 DOI: 10.1021/Jm960561U |
0.376 |
|
| 1996 |
Mathews GC, Bolos-Sy AM, Covey DF, Rothman SM, Ferrendelli JA. Physiological comparison of alpha-ethyl-alpha-methyl-gamma-thiobutyrolactone with benzodiazepine and barbiturate modulators of GABAA receptors. Neuropharmacology. 35: 123-36. PMID 8734480 DOI: 10.1016/0028-3908(95)00180-8 |
0.37 |
|
| 1995 |
Holland KD, Mathews GC, Bolos-Sy AM, Tucker JB, Reddy PA, Covey DF, Ferrendelli JA, Rothman SM. Dual modulation of the gamma-aminobutyric acid type A receptor/ionophore by alkyl-substituted gamma-butyrolactones. Molecular Pharmacology. 47: 1217-23. PMID 7603463 |
0.323 |
|
| 1994 |
Peterson EM, Xu K, Holland KD, McKeon AC, Rothman SM, Ferrendelli JA, Covey DF. Alpha-spirocyclopentyl- and alpha-spirocyclopropyl-gamma-butyrolactones: conformationally constrained derivatives of anticonvulsant and convulsant alpha,alpha-disubstituted gamma-butyrolactones. Journal of Medicinal Chemistry. 37: 275-86. PMID 8295215 DOI: 10.1021/Jm00028A011 |
0.394 |
|
| 1994 |
Moudy AM, Yamada KA, Rothman SM. Rapid desensitization determines the pharmacology of glutamate neurotoxicity. Neuropharmacology. 33: 953-62. PMID 7845551 DOI: 10.1016/0028-3908(94)90153-8 |
0.375 |
|
| 1994 |
Rothman SM. Excitotoxic neuronal death: Mechanisms and clinical relevance Seminars in the Neurosciences. 6: 315-322. DOI: 10.1006/smns.1994.1040 |
0.343 |
|
| 1993 |
Yoon KW, Covey DF, Rothman SM. Multiple mechanisms of picrotoxin block of GABA-induced currents in rat hippocampal neurons. The Journal of Physiology. 464: 423-39. PMID 8229811 DOI: 10.1113/Jphysiol.1993.Sp019643 |
0.59 |
|
| 1993 |
Rothman SM, Yamada KA, Lancaster N. Nordihydroguaiaretic acid attenuates NMDA neurotoxicity--action beyond the receptor. Neuropharmacology. 32: 1279-88. PMID 7509052 DOI: 10.1016/0028-3908(93)90022-U |
0.373 |
|
| 1992 |
Yamada KA, Rothman SM. Diazoxide blocks glutamate desensitization and prolongs excitatory postsynaptic currents in rat hippocampal neurons. The Journal of Physiology. 458: 409-23. PMID 1302270 DOI: 10.1113/Jphysiol.1992.Sp019424 |
0.428 |
|
| 1991 |
Yoon KW, Rothman SM. Adenosine inhibits excitatory but not inhibitory synaptic transmission in the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 1375-80. PMID 1851219 DOI: 10.1523/Jneurosci.11-05-01375.1991 |
0.57 |
|
| 1991 |
Holland KD, Yoon KW, Ferrendelli JA, Covey DF, Rothman SM. Gamma-butyrolactone antagonism of the picrotoxin receptor: comparison of a pure antagonist and a mixed antagonist/inverse agonist. Molecular Pharmacology. 39: 79-84. PMID 1846222 |
0.545 |
|
| 1991 |
Dubinsky JM, Rothman SM. Intracellular calcium concentrations during "chemical hypoxia" and excitotoxic neuronal injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 2545-51. PMID 1678427 DOI: 10.1523/Jneurosci.11-08-02545.1991 |
0.325 |
|
| 1991 |
Yoon KW, Rothman SM. The modulation of rat hippocampal synaptic conductances by baclofen and gamma-aminobutyric acid. The Journal of Physiology. 442: 377-90. PMID 1665862 DOI: 10.1113/Jphysiol.1991.Sp018798 |
0.588 |
|
| 1990 |
Holland KD, Ferrendelli JA, Covey DF, Rothman SM. Physiological regulation of the picrotoxin receptor by gamma-butyrolactones and gamma-thiobutyrolactones in cultured hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 1719-27. PMID 2355246 DOI: 10.1523/Jneurosci.10-06-01719.1990 |
0.392 |
|
| 1990 |
Holland KD, Canney DJ, Rothman SM, Ferrendelli JA, Covey DF. Physiological modulation of the GABA receptor by convulsant and anticonvulsant barbiturates in cultured rat hippocampal neurons. Brain Research. 516: 147-50. PMID 2163720 DOI: 10.1016/0006-8993(90)90910-4 |
0.434 |
|
| 1990 |
Michaels RL, Rothman SM. Glutamate neurotoxicity in vitro: antagonist pharmacology and intracellular calcium concentrations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 283-92. PMID 1967639 DOI: 10.1523/Jneurosci.10-01-00283.1990 |
0.375 |
|
| 1990 |
Yoon KW, Canney DJ, Covey DF, Rothman SM. Modulation of the picrotoxin receptor by fluorinated ethyl, methyl-butyrolactones. The Journal of Pharmacology and Experimental Therapeutics. 255: 248-55. PMID 1698968 |
0.558 |
|
| 1989 |
Yamada KA, Rothman SM. Glutamine currents in hippocampal neurons are attributable to contaminating glutamate. Brain Research. 498: 351-4. PMID 2571397 DOI: 10.1016/0006-8993(89)91115-3 |
0.37 |
|
| 1987 |
Rothman SM, Olney JW. Excitotoxity and the NMDA receptor Trends in Neurosciences. 10: 299-302. DOI: 10.1016/0166-2236(87)90177-9 |
0.385 |
|
| 1986 |
Rothman SM, Olney JW. Glutamate and the pathophysiology of hypoxic--ischemic brain damage. Annals of Neurology. 19: 105-11. PMID 2421636 DOI: 10.1002/Ana.410190202 |
0.363 |
|
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