Steven M Rothman - Publications

Affiliations: 
Washington University, Saint Louis, St. Louis, MO 

43/155 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Yang XF, Schmidt BF, Rode DL, Rothman SM. Optical suppression of experimental seizures in rat brain slices. Epilepsia. 51: 127-35. PMID 19674053 DOI: 10.1111/j.1528-1167.2009.02252.x  0.323
2008 Xu L, Rensing N, Yang XF, Zhang HX, Thio LL, Rothman SM, Weisenfeld AE, Wong M, Yamada KA. Leptin inhibits 4-aminopyridine- and pentylenetetrazole-induced seizures and AMPAR-mediated synaptic transmission in rodents. The Journal of Clinical Investigation. 118: 272-80. PMID 18097472 DOI: 10.1172/JCI33009  0.305
2007 Zeng LH, Xu L, Rensing NR, Sinatra PM, Rothman SM, Wong M. Kainate seizures cause acute dendritic injury and actin depolymerization in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 11604-13. PMID 17959803 DOI: 10.1523/JNEUROSCI.0983-07.2007  0.35
2007 Rothman SM, Perry G, Yang XF, Hyrc K, Schmidt BF. Optical suppression of seizure-like activity with an LED. Epilepsy Research. 74: 201-9. PMID 17448638 DOI: 10.1016/j.eplepsyres.2007.03.009  0.326
2006 Yang XF, Kennedy BR, Lomber SG, Schmidt RE, Rothman SM. Cooling produces minimal neuropathology in neocortex and hippocampus. Neurobiology of Disease. 23: 637-43. PMID 16828292 DOI: 10.1016/J.Nbd.2006.05.006  0.307
2006 Griffey MA, Wozniak D, Wong M, Bible E, Johnson K, Rothman SM, Wentz AE, Cooper JD, Sands MS. CNS-directed AAV2-mediated gene therapy ameliorates functional deficits in a murine model of infantile neuronal ceroid lipofuscinosis. Molecular Therapy : the Journal of the American Society of Gene Therapy. 13: 538-47. PMID 16364693 DOI: 10.1016/J.Ymthe.2005.11.008  0.321
2005 Burton JM, Peebles GA, Binder DK, Rothman SM, Smyth MD. Transcortical cooling inhibits hippocampal-kindled seizures in the rat. Epilepsia. 46: 1881-7. PMID 16393153 DOI: 10.1111/j.1528-1167.2005.00299.x  0.313
2005 Yang XF, Ouyang Y, Kennedy BR, Rothman SM. Cooling blocks rat hippocampal neurotransmission by a presynaptic mechanism: observations using 2-photon microscopy. The Journal of Physiology. 567: 215-24. PMID 15961429 DOI: 10.1113/jphysiol.2005.088948  0.329
2004 Chang JH, Yang XF, Zempel JM, Rothman SM. The unilateral cobalt wire model of neocortical epilepsy: a method of producing subacute focal seizures in rodents. Epilepsy Research. 61: 153-60. PMID 15451016 DOI: 10.1016/j.eplepsyres.2004.07.012  0.307
2004 Griffey M, Wozniak D, Wong M, Rothman S, Bible E, Cooper J, Vogler C, Sands M. AAV-mediated gene therapy causes functional improvements in a murine model of infantile neuronal ceroid lipofuscinosis (INCL, Batten disease) Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.05.065  0.309
2003 Yang XF, Chang JH, Rothman SM. Long-lasting anticonvulsant effect of focal cooling on experimental neocortical seizures. Epilepsia. 44: 1500-5. PMID 14636319 DOI: 10.1111/j.0013-9580.2003.23003.x  0.317
2002 Xia S, Cai ZY, Thio LL, Kim-Han JS, Dugan LL, Covey DF, Rothman SM. The estrogen receptor is not essential for all estrogen neuroprotection: new evidence from a new analog. Neurobiology of Disease. 9: 282-93. PMID 11950274 DOI: 10.1006/Nbdi.2002.0478  0.361
2001 Yang XF, Rothman SM. Focal cooling rapidly terminates experimental neocortical seizures. Annals of Neurology. 49: 721-6. PMID 11409423 DOI: 10.1002/ana.1021  0.321
2000 Hill MW, Wong M, Amarakone A, Rothman SM. Rapid cooling aborts seizure-like activity in rodent hippocampal-entorhinal slices. Epilepsia. 41: 1241-8. PMID 11051118 DOI: 10.1111/J.1528-1157.2000.Tb04601.X  0.315
2000 Werth JL, Deshmukh M, Cocabo J, Johnson EM, Rothman SM. Reversible physiological alterations in sympathetic neurons deprived of NGF but protected from apoptosis by caspase inhibition or Bax deletion. Experimental Neurology. 161: 203-11. PMID 10683286 DOI: 10.1006/Exnr.1999.7241  0.315
1999 Hill MW, de la Cruz MA, Covey DF, Rothman SM. Effects of anticonvulsant lactams on in vitro seizures in the hippocampal slice preparation. Epilepsy Research. 37: 121-31. PMID 10510978 DOI: 10.1016/S0920-1211(99)00041-8  0.454
1998 Hill MW, Reddy PA, Covey DF, Rothman SM. Contribution of subsaturating GABA concentrations to IPSCs in cultured hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 5103-11. PMID 9651194  0.322
1998 Hill MW, Reddy PA, Covey DF, Rothman SM. Inhibition of voltage-dependent sodium channels by the anticonvulsant gamma-aminobutyric acid type A receptor modulator, 3-benzyl-3-ethyl-2-piperidinone. The Journal of Pharmacology and Experimental Therapeutics. 285: 1303-9. PMID 9618437  0.337
1998 Werth JL, Park TS, Silbergeld DL, Rothman SM. Excitotoxic swelling occurs in oxygen and glucose deprived human cortical slices. Brain Research. 782: 248-54. PMID 9519270 DOI: 10.1016/S0006-8993(97)01286-9  0.374
1998 Canney DJ, Lu HF, McKeon AC, Yoon KW, Xu K, Holland KD, Rothman SM, Ferrendelli JA, Covey DF. Structure-activity studies of fluoroalkyl-substituted gamma-butyrolactone and gamma-thiobutyrolactone modulators of GABA(A) receptor function. Bioorganic & Medicinal Chemistry. 6: 43-55. PMID 9502104 DOI: 10.1016/S0968-0896(97)10006-2  0.549
1998 Hill MW, Reddy PA, Covey DF, Rothman SM. Contribution of Subsaturating GABA Concentrations to IPSCs in Cultured Hippocampal Neurons The Journal of Neuroscience. 18: 5103-5111. DOI: 10.1523/Jneurosci.18-14-05103.1998  0.318
1997 Hyrc K, Handran SD, Rothman SM, Goldberg MP. Ionized intracellular calcium concentration predicts excitotoxic neuronal death: observations with low-affinity fluorescent calcium indicators. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 6669-77. PMID 9254679 DOI: 10.1523/Jneurosci.17-17-06669.1997  0.319
1997 Williams KL, Tucker JB, White G, Weiss DS, Ferrendelli JA, Covey DF, Krause JE, Rothman SM. Lactone modulation of the gamma-aminobutyric acid A receptor: evidence for a positive modulatory site. Molecular Pharmacology. 52: 114-9. PMID 9224820 DOI: 10.1124/Mol.52.1.114  0.412
1997 Reddy PA, Woodward KE, McIlheran SM, Hsiang BC, Latifi TN, Hill MW, Rothman SM, Ferrendelli JA, Covey DF. Synthesis and anticonvulsant activities of 3,3-dialkyl- and 3-alkyl-3-benzyl-2-piperidinones (delta-valerolactams) and hexahydro-2H-azepin-2-ones (epsilon-caprolactams). Journal of Medicinal Chemistry. 40: 44-9. PMID 9016327 DOI: 10.1021/Jm960561U  0.376
1996 Mathews GC, Bolos-Sy AM, Covey DF, Rothman SM, Ferrendelli JA. Physiological comparison of alpha-ethyl-alpha-methyl-gamma-thiobutyrolactone with benzodiazepine and barbiturate modulators of GABAA receptors. Neuropharmacology. 35: 123-36. PMID 8734480 DOI: 10.1016/0028-3908(95)00180-8  0.37
1995 Holland KD, Mathews GC, Bolos-Sy AM, Tucker JB, Reddy PA, Covey DF, Ferrendelli JA, Rothman SM. Dual modulation of the gamma-aminobutyric acid type A receptor/ionophore by alkyl-substituted gamma-butyrolactones. Molecular Pharmacology. 47: 1217-23. PMID 7603463  0.323
1994 Peterson EM, Xu K, Holland KD, McKeon AC, Rothman SM, Ferrendelli JA, Covey DF. Alpha-spirocyclopentyl- and alpha-spirocyclopropyl-gamma-butyrolactones: conformationally constrained derivatives of anticonvulsant and convulsant alpha,alpha-disubstituted gamma-butyrolactones. Journal of Medicinal Chemistry. 37: 275-86. PMID 8295215 DOI: 10.1021/Jm00028A011  0.394
1994 Moudy AM, Yamada KA, Rothman SM. Rapid desensitization determines the pharmacology of glutamate neurotoxicity. Neuropharmacology. 33: 953-62. PMID 7845551 DOI: 10.1016/0028-3908(94)90153-8  0.375
1994 Rothman SM. Excitotoxic neuronal death: Mechanisms and clinical relevance Seminars in the Neurosciences. 6: 315-322. DOI: 10.1006/smns.1994.1040  0.343
1993 Yoon KW, Covey DF, Rothman SM. Multiple mechanisms of picrotoxin block of GABA-induced currents in rat hippocampal neurons. The Journal of Physiology. 464: 423-39. PMID 8229811 DOI: 10.1113/Jphysiol.1993.Sp019643  0.59
1993 Rothman SM, Yamada KA, Lancaster N. Nordihydroguaiaretic acid attenuates NMDA neurotoxicity--action beyond the receptor. Neuropharmacology. 32: 1279-88. PMID 7509052 DOI: 10.1016/0028-3908(93)90022-U  0.373
1992 Yamada KA, Rothman SM. Diazoxide blocks glutamate desensitization and prolongs excitatory postsynaptic currents in rat hippocampal neurons. The Journal of Physiology. 458: 409-23. PMID 1302270 DOI: 10.1113/Jphysiol.1992.Sp019424  0.428
1991 Yoon KW, Rothman SM. Adenosine inhibits excitatory but not inhibitory synaptic transmission in the hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 1375-80. PMID 1851219 DOI: 10.1523/Jneurosci.11-05-01375.1991  0.57
1991 Holland KD, Yoon KW, Ferrendelli JA, Covey DF, Rothman SM. Gamma-butyrolactone antagonism of the picrotoxin receptor: comparison of a pure antagonist and a mixed antagonist/inverse agonist. Molecular Pharmacology. 39: 79-84. PMID 1846222  0.545
1991 Dubinsky JM, Rothman SM. Intracellular calcium concentrations during "chemical hypoxia" and excitotoxic neuronal injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 11: 2545-51. PMID 1678427 DOI: 10.1523/Jneurosci.11-08-02545.1991  0.325
1991 Yoon KW, Rothman SM. The modulation of rat hippocampal synaptic conductances by baclofen and gamma-aminobutyric acid. The Journal of Physiology. 442: 377-90. PMID 1665862 DOI: 10.1113/Jphysiol.1991.Sp018798  0.588
1990 Holland KD, Ferrendelli JA, Covey DF, Rothman SM. Physiological regulation of the picrotoxin receptor by gamma-butyrolactones and gamma-thiobutyrolactones in cultured hippocampal neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 1719-27. PMID 2355246 DOI: 10.1523/Jneurosci.10-06-01719.1990  0.392
1990 Holland KD, Canney DJ, Rothman SM, Ferrendelli JA, Covey DF. Physiological modulation of the GABA receptor by convulsant and anticonvulsant barbiturates in cultured rat hippocampal neurons. Brain Research. 516: 147-50. PMID 2163720 DOI: 10.1016/0006-8993(90)90910-4  0.434
1990 Michaels RL, Rothman SM. Glutamate neurotoxicity in vitro: antagonist pharmacology and intracellular calcium concentrations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 10: 283-92. PMID 1967639 DOI: 10.1523/Jneurosci.10-01-00283.1990  0.375
1990 Yoon KW, Canney DJ, Covey DF, Rothman SM. Modulation of the picrotoxin receptor by fluorinated ethyl, methyl-butyrolactones. The Journal of Pharmacology and Experimental Therapeutics. 255: 248-55. PMID 1698968  0.558
1989 Yamada KA, Rothman SM. Glutamine currents in hippocampal neurons are attributable to contaminating glutamate. Brain Research. 498: 351-4. PMID 2571397 DOI: 10.1016/0006-8993(89)91115-3  0.37
1987 Rothman SM, Olney JW. Excitotoxity and the NMDA receptor Trends in Neurosciences. 10: 299-302. DOI: 10.1016/0166-2236(87)90177-9  0.385
1986 Rothman SM, Olney JW. Glutamate and the pathophysiology of hypoxic--ischemic brain damage. Annals of Neurology. 19: 105-11. PMID 2421636 DOI: 10.1002/Ana.410190202  0.363
Low-probability matches (unlikely to be authored by this person)
1995 Dugan LL, Sensi SL, Canzoniero LM, Handran SD, Rothman SM, Lin TS, Goldberg MP, Choi DW. Mitochondrial production of reactive oxygen species in cortical neurons following exposure to N-methyl-D-aspartate. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 15: 6377-88. PMID 7472402 DOI: 10.1523/Jneurosci.15-10-06377.1995  0.299
1995 Rothman SM, Olney JW. Excitotoxicity and the NMDA receptor--still lethal after eight years. Trends in Neurosciences. 18: 57-8. PMID 7537407 DOI: 10.1016/0166-2236(95)80017-V  0.296
1996 Reddy PA, Hsiang BC, Latifi TN, Hill MW, Woodward KE, Rothman SM, Ferrendelli JA, Covey DF. 3,3-Dialkyl- and 3-alkyl-3-benzyl-substituted 2-pyrrolidinones: a new class of anticonvulsant agents. Journal of Medicinal Chemistry. 39: 1898-906. PMID 8627613 DOI: 10.1021/Jm9600196  0.294
2002 Yang XF, Chang JH, Rothman SM. Intracerebral temperature alterations associated with focal seizures. Epilepsy Research. 52: 97-105. PMID 12458026 DOI: 10.1016/S0920-1211(02)00193-6  0.291
2003 Rothman S, Yang X. Local Cooling: A Therapy for Intractable Neocortical Epilepsy Epilepsy Currents. 3: 153-156. PMID 15346164 DOI: 10.1046/J.1535-7597.2003.03501.X  0.288
2005 Rothman SM, Smyth MD, Yang XF, Peterson GP. Focal cooling for epilepsy: an alternative therapy that might actually work. Epilepsy & Behavior : E&B. 7: 214-21. PMID 16046277 DOI: 10.1016/j.yebeh.2005.05.021  0.287
1989 Yamada KA, Dubinsky JM, Rothman SM. Quantitative physiological characterization of a quinoxalinedione non-NMDA receptor antagonist. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 9: 3230-6. PMID 2571688  0.284
1985 Rothman SM, Samaie M. Physiology of excitatory synaptic transmission in cultures of dissociated rat hippocampus. Journal of Neurophysiology. 54: 701-13. PMID 2864404  0.282
1983 Rothman SM, Bischoff R. Electrophysiology of Duchenne dystrophy myotubes in tissue culture. Annals of Neurology. 13: 176-9. PMID 6830176 DOI: 10.1002/ana.410130212  0.281
2014 Rothman SM, Glass HC, Chang T, Sullivan JE, Bonifacio SL, Shellhaas RA. Risk factors for EEG seizures in neonates treated with hypothermia: a multicenter cohort study. Neurology. 83: 1773-4. PMID 25367061 DOI: 10.1212/01.wnl.0000456637.05253.24  0.278
1987 Clark GD, Rothman SM. Blockade of excitatory amino acid receptors protects anoxic hippocampal slices. Neuroscience. 21: 665-71. PMID 2888040 DOI: 10.1016/0306-4522(87)90027-3  0.276
2012 Meehan AL, Yang X, Yuan LL, Rothman SM. Levetiracetam has an activity-dependent effect on inhibitory transmission. Epilepsia. 53: 469-76. PMID 22292611 DOI: 10.1111/j.1528-1167.2011.03392.x  0.276
1987 Rothman SM, Thurston JH, Hauhart RE, Clark GD, Solomon JS. Ketamine protects hippocampal neurons from anoxia in vitro. Neuroscience. 21: 673-8. PMID 2819768 DOI: 10.1016/0306-4522(87)90028-5  0.27
2002 Xiao AY, Wei L, Xia S, Rothman S, Yu SP. Ionic mechanism of ouabain-induced concurrent apoptosis and necrosis in individual cultured cortical neurons Journal of Neuroscience. 22: 1350-1362. PMID 11850462 DOI: 10.1523/Jneurosci.22-04-01350.2002  0.266
1994 Mathews GC, Bolos-Sy AM, Holland KD, Isenberg KE, Covey DF, Ferrendelli JA, Rothman SM. Developmental alteration in GABAA receptor structure and physiological properties in cultured cerebellar granule neurons. Neuron. 13: 149-58. PMID 8043274 DOI: 10.1016/0896-6273(94)90465-0  0.265
2012 Yang X, Rode DL, Peterka DS, Yuste R, Rothman SM. Optical control of focal epilepsy in vivo with caged γ-aminobutyric acid. Annals of Neurology. 71: 68-75. PMID 22275253 DOI: 10.1002/ana.22596  0.265
1984 Rothman S. Synaptic release of excitatory amino acid neurotransmitter mediates axonic neuronal death Journal of Neuroscience. 4: 1884-1891. PMID 6737044  0.26
1995 Moudy AM, Handran SD, Goldberg MP, Ruffin N, Karl I, Kranz-Eble P, DeVivo DC, Rothman SM. Abnormal calcium homeostasis and mitochondrial polarization in a human encephalomyopathy. Proceedings of the National Academy of Sciences of the United States of America. 92: 729-33. PMID 7846043 DOI: 10.1073/pnas.92.3.729  0.246
1999 Rothman SM. Mutations of the mitochondrial genome: clinical overview and possible pathophysiology of cell damage. Biochemical Society Symposium. 66: 111-22. PMID 10989662 DOI: 10.1042/Bss0660111  0.235
1987 Rothman SM, Thurston JH, Hauhart RE. Delayed neurotoxicity of excitatory amino acids in vitro. Neuroscience. 22: 471-80. PMID 3670595 DOI: 10.1016/0306-4522(87)90347-2  0.235
1997 Handran SD, Werth JL, DeVivo DC, Rothman SM. Mitochondrial morphology and intracellular calcium homeostasis in cytochrome oxidase-deficient human fibroblasts. Neurobiology of Disease. 3: 287-98. PMID 9173926 DOI: 10.1006/nbdi.1996.0125  0.233
1992 Rothman SM. Excitotoxins: possible mechanisms of action. Annals of the New York Academy of Sciences. 648: 132-9. PMID 1353327 DOI: 10.1111/J.1749-6632.1992.Tb24531.X  0.228
1978 Levisohn PM, Mikhael MA, Rothman SM. Cerebrovascular changes in neurofibromatosis. Developmental Medicine and Child Neurology. 20: 789-93. PMID 103764 DOI: 10.1111/J.1469-8749.1978.Tb15311.X  0.223
1985 Rothman SM. The neurotoxicity of excitatory amino acids is produced by passive chloride influx. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 5: 1483-9. PMID 3925091  0.222
1986 Rothman SM, Fulling KH, Nelson JS. Sickle cell anemia and central nervous system infarction: a neuropathological study. Annals of Neurology. 20: 684-90. PMID 3813497 DOI: 10.1002/ana.410200606  0.219
2005 Rensing N, Ouyang Y, Yang XF, Yamada KA, Rothman SM, Wong M. In vivo imaging of dendritic spines during electrographic seizures. Annals of Neurology. 58: 888-98. PMID 16240365 DOI: 10.1002/ana.20658  0.214
1983 Rothman SM. Synaptic activity mediates death of hypoxic neurons. Science (New York, N.Y.). 220: 536-7. PMID 6836300  0.214
2004 Rothman SM. Pediatric neurology's midlife crisis. Neurology. 62: 845-6. PMID 15037678 DOI: 10.1212/Wnl.62.6.845  0.213
2011 Meehan AL, Yang X, McAdams BD, Yuan L, Rothman SM. A new mechanism for antiepileptic drug action: vesicular entry may mediate the effects of levetiracetam. Journal of Neurophysiology. 106: 1227-39. PMID 21653714 DOI: 10.1152/jn.00279.2011  0.21
2009 Rothman SM. The therapeutic potential of focal cooling for neocortical epilepsy. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 6: 251-7. PMID 19332317 DOI: 10.1016/j.nurt.2008.12.002  0.21
1988 Rothman S. Noncompetitive N-methyl-D-aspartate antagonists affect multiple ionic currents Journal of Pharmacology and Experimental Therapeutics. 246: 137-142. PMID 2455788  0.21
1983 Shaywitz BA, Shaywitz SE, Byrne T, Cohen DJ, Rothman S. Attention deficit disorder: Quantitative analysis of CT Neurology. 33: 1500-1503. PMID 6685244 DOI: 10.1212/Wnl.33.11.1500  0.209
1979 Rothman SM, Nelson JS, DeVivo DC, Coxe WS. Congenital astrocytoma presenting with intracerebral hematoma. Case report. Journal of Neurosurgery. 51: 237-9. PMID 448433 DOI: 10.3171/Jns.1979.51.2.0237  0.199
1986 Rothman SM. Glutamate and anoxic neuronal death in vitro. Advances in Experimental Medicine and Biology. 203: 687-95. PMID 2878576  0.198
1980 Rothman SM, Nelson JS. Spinal cord infarction in a patient with sickle cell anemia. Neurology. 30: 1072-6. PMID 7191498 DOI: 10.1212/Wnl.30.10.1072  0.198
2015 Yang X, Meehan AL, Rothman SM, Dubinsky JM. Seletracetam enhances short term depression in vitro. Epilepsy Research. 117: 17-22. PMID 26320080 DOI: 10.1016/j.eplepsyres.2015.08.006  0.198
2013 Rothman SM. Pediatric neuroenhancement: ethical, legal, social, and neurodevelopmental implications. Neurology. 81: 1558. PMID 24145884 DOI: 10.1212/01.Wnl.0000437277.02794.3A  0.196
2002 Schechtman KB, Gray DL, Baty JD, Rothman SM. Decision-making for termination of pregnancies with fetal anomalies: analysis of 53,000 pregnancies. Obstetrics and Gynecology. 99: 216-22. PMID 11814500 DOI: 10.1016/S0029-7844(01)01673-8  0.194
2009 Yang XF, Rothman SM. Levetiracetam has a time- and stimulation-dependent effect on synaptic transmission. Seizure. 18: 615-9. PMID 19651528 DOI: 10.1016/j.seizure.2009.07.004  0.189
2002 Yang XF, Duffy DW, Morley RE, Rothman SM. Neocortical seizure termination by focal cooling: temperature dependence and automated seizure detection. Epilepsia. 43: 240-5. PMID 11906508 DOI: 10.1046/j.1528-1157.2002.33301.x  0.186
2015 Yang X, Bognar J, He T, Mohammed M, Niespodziany I, Wolff C, Esguerra M, Rothman SM, Dubinsky JM. Brivaracetam augments short-term depression and slows vesicle recycling. Epilepsia. 56: 1899-909. PMID 26515103 DOI: 10.1111/Epi.13223  0.185
2013 D'Ambrosio R, Eastman CL, Darvas F, Fender JS, Verley DR, Farin FM, Wilkerson HW, Temkin NR, Miller JW, Ojemann J, Rothman SM, Smyth MD. Mild passive focal cooling prevents epileptic seizures after head injury in rats. Annals of Neurology. 73: 199-209. PMID 23225633 DOI: 10.1002/Ana.23764  0.177
2007 Yang XF, Weisenfeld A, Rothman SM. Prolonged exposure to levetiracetam reveals a presynaptic effect on neurotransmission. Epilepsia. 48: 1861-9. PMID 17521346 DOI: 10.1111/j.1528-1167.2006.01132.x  0.174
1992 Rothman S. Mechanisms of excitotoxic neuronal death Experimental Eye Research. 55: 181. DOI: 10.1016/0014-4835(92)90832-D  0.153
2002 Xia S, Lampe PA, Deshmukh M, Yang A, Brown BS, Rothman SM, Johnson EM, Yu SP. Multiple channel interactions explain the protection of sympathetic neurons from apoptosis induced by nerve growth factor deprivation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 114-22. PMID 11756494 DOI: 10.1523/Jneurosci.22-01-00114.2002  0.15
1996 Rothman SM, Yamada KA, Covey DF. Thiazide derivatives block rapid AMPA receptordesensitization European Neuropsychopharmacology. 6: 152. DOI: 10.1016/0924-977X(96)88007-2  0.149
2015 Smyth MD, Han RH, Yarbrough CK, Patterson EE, Yang XF, Miller JW, Rothman SM, D'Ambrosio R. Temperatures Achieved in Human and Canine Neocortex During Intraoperative Passive or Active Focal Cooling. Therapeutic Hypothermia and Temperature Management. 5: 95-103. PMID 25902001 DOI: 10.1089/Ther.2014.0025  0.149
2011 Smyth MD, Rothman SM. Focal cooling devices for the surgical treatment of epilepsy. Neurosurgery Clinics of North America. 22: 533-46, vii. PMID 21939851 DOI: 10.1016/j.nec.2011.07.011  0.148
2013 Rothman SM, Mattson MP. Activity-dependent, stress-responsive BDNF signaling and the quest for optimal brain health and resilience throughout the lifespan. Neuroscience. 239: 228-40. PMID 23079624 DOI: 10.1016/J.Neuroscience.2012.10.014  0.141
1990 Choi DW, Rothman SM. The role of glutamate neurotoxicity in hypoxic-ischemic neuronal death. Annual Review of Neuroscience. 13: 171-82. PMID 1970230 DOI: 10.1146/Annurev.Ne.13.030190.001131  0.134
2008 Rothman SM. Beyond Prediction - Focal Cooling and Optical Activation to Terminate Focal Seizures Seizure Prediction in Epilepsy: From Basic Mechanisms to Clinical Applications. 269-282. DOI: 10.1002/9783527625192.ch21  0.132
1981 Rothman S, Cowan WM. A scanning electron microscope study of the in vitro development of dissociated hippocampal cells. The Journal of Comparative Neurology. 195: 141-55. PMID 7204649 DOI: 10.1002/cne.901950108  0.131
2010 Moore BM, Rothman SM, Clark HB, Vehe RK, Laguna TA. Epilepsy: an anticipatory presentation of pediatric Wegener's granulomatosis. Pediatric Neurology. 43: 49-52. PMID 20682204 DOI: 10.1016/J.Pediatrneurol.2010.03.014  0.129
2012 Mohammed HS, Kaufman CB, Limbrick DD, Steger-May K, Grubb RL, Rothman SM, Weisenberg JL, Munro R, Smyth MD. Impact of epilepsy surgery on seizure control and quality of life: a 26-year follow-up study. Epilepsia. 53: 712-20. PMID 22313356 DOI: 10.1111/J.1528-1167.2011.03398.X  0.124
2012 Rothman SM, Griffioen KJ, Wan R, Mattson MP. Brain-derived neurotrophic factor as a regulator of systemic and brain energy metabolism and cardiovascular health. Annals of the New York Academy of Sciences. 1264: 49-63. PMID 22548651 DOI: 10.1111/J.1749-6632.2012.06525.X  0.099
2012 Rothman SM. Regarding the beautiful and ethereal neurological exam. Annals of Neurology. 71: 432. PMID 22451208 DOI: 10.1002/ana.23534  0.096
2009 Rothman SM, Huang Z, Lee KE, Weisshaar CL, Winkelstein BA. Cytokine mRNA expression in painful radiculopathy. The Journal of Pain : Official Journal of the American Pain Society. 10: 90-9. PMID 18848809 DOI: 10.1016/J.Jpain.2008.07.008  0.095
1978 Carpenter S, Karpati G, Rothman S, Watters G, Andermann F. Pathological involvement of primary sensory neurons in Werdnig-Hoffmann disease Acta Neuropathologica. 42: 91-97. PMID 654890 DOI: 10.1007/BF00690973  0.095
2007 Hilderbrand JK, Peterson GP, Rothman SM. Development of phase change heat spreader for treatment of intractable neocortical epilepsy Heat Transfer Engineering. 28: 282-291. DOI: 10.1080/01457630601117872  0.093
2013 Griffioen KJ, Rothman SM, Ladenheim B, Wan R, Vranis N, Hutchison E, Okun E, Cadet JL, Mattson MP. Dietary energy intake modifies brainstem autonomic dysfunction caused by mutant α-synuclein. Neurobiology of Aging. 34: 928-35. PMID 22883907 DOI: 10.1016/J.Neurobiolaging.2012.07.008  0.091
2007 Rothman SM, Winkelstein BA. Chemical and mechanical nerve root insults induce differential behavioral sensitivity and glial activation that are enhanced in combination. Brain Research. 1181: 30-43. PMID 17920051 DOI: 10.1016/J.Brainres.2007.08.064  0.082
2010 Rothman SM, Nicholson KJ, Winkelstein BA. Time-dependent mechanics and measures of glial activation and behavioral sensitivity in a rodent model of radiculopathy. Journal of Neurotrauma. 27: 803-14. PMID 20121422 DOI: 10.1089/Neu.2009.1045  0.082
2010 Rothman SM, Winkelstein BA. Cytokine antagonism reduces pain and modulates spinal astrocytic reactivity after cervical nerve root compression. Annals of Biomedical Engineering. 38: 2563-76. PMID 20309734 DOI: 10.1007/S10439-010-0012-8  0.079
2012 Okun E, Barak B, Saada-Madar R, Rothman SM, Griffioen KJ, Roberts N, Castro K, Mughal MR, Pita MA, Stranahan AM, Arumugam TV, Mattson MP. Evidence for a developmental role for TLR4 in learning and memory. Plos One. 7: e47522. PMID 23071817 DOI: 10.1371/Journal.Pone.0047522  0.078
2011 Orchard PJ, Lund T, Miller W, Rothman SM, Raymond G, Nascene D, Basso L, Cloyd J, Tolar J. Chitotriosidase as a biomarker of cerebral adrenoleukodystrophy. Journal of Neuroinflammation. 8: 144. PMID 22014002 DOI: 10.1186/1742-2094-8-144  0.077
2010 Miller WP, Rothman S, Nascene D, Kivisto T, Defor T, Lund T, Tolar J, Orchard P. Outcomes Following Allogeneic Hematopoietic Stem Cell Transplantation for Childhood Cerebral Variant Adrenoleukodystrophy: A Modern, Single-Institution Experience Blood. 116: 3543-3543. DOI: 10.1182/BLOOD.V116.21.3543.3543  0.075
2002 Butler RN, Fossel M, Harman SM, Heward CB, Olshansky SJ, Perls TT, Rothman DJ, Rothman SM, Warner HR, West MD, Wright WE. Is there an antiaging medicine? The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 57: B333-8. PMID 12196485 DOI: 10.1093/Gerona/57.9.B333  0.075
2013 Rothman SM, Griffioen KJ, Vranis N, Ladenheim B, Cong WN, Cadet JL, Haran J, Martin B, Mattson MP. Neuronal expression of familial Parkinson's disease A53T α-synuclein causes early motor impairment, reduced anxiety and potential sleep disturbances in mice. Journal of Parkinson's Disease. 3: 215-29. PMID 23938351 DOI: 10.3233/Jpd-120130  0.075
2012 Texel SJ, Camandola S, Ladenheim B, Rothman SM, Mughal MR, Unger EL, Cadet JL, Mattson MP. Ceruloplasmin deficiency results in an anxiety phenotype involving deficits in hippocampal iron, serotonin, and BDNF. Journal of Neurochemistry. 120: 125-34. PMID 22035068 DOI: 10.1111/J.1471-4159.2011.07554.X  0.074
2009 Rothman SM, Guarino BB, Winkelstein BA. Spinal microglial proliferation is evident in a rat model of painful disc herniation both in the presence of behavioral hypersensitivity and following minocycline treatment sufficient to attenuate allodynia. Journal of Neuroscience Research. 87: 2709-17. PMID 19382225 DOI: 10.1002/Jnr.22090  0.071
2005 Rothman SM, Kreider RA, Winkelstein BA. Spinal neuropeptide responses in persistent and transient pain following cervical nerve root injury. Spine. 30: 2491-6. PMID 16284585 DOI: 10.1097/01.Brs.0000186316.38111.4B  0.064
2005 Harding JD, Piacentino V, Rothman S, Chambers S, Jessup M, Margulies KB. Prolonged repolarization after ventricular assist device support is associated with arrhythmias in humans with congestive heart failure. Journal of Cardiac Failure. 11: 227-32. PMID 15812752 DOI: 10.1016/J.Cardfail.2004.08.158  0.064
2010 Rothman SM, Mattson MP. Adverse stress, hippocampal networks, and Alzheimer's disease. Neuromolecular Medicine. 12: 56-70. PMID 19943124 DOI: 10.1007/S12017-009-8107-9  0.064
2014 Rothman SM, Griffioen KJ, Fishbein KW, Spencer RG, Makrogiannis S, Cong WN, Martin B, Mattson MP. Metabolic abnormalities and hypoleptinemia in α-synuclein A53T mutant mice. Neurobiology of Aging. 35: 1153-61. PMID 24239384 DOI: 10.1016/J.Neurobiolaging.2013.10.088  0.063
2010 REDDY PA, HSIANG BCH, LATIFI TN, HILL MW, WOODWARD KE, ROTHMAN SM, FERRENDELLI JA, COVEY DF. ChemInform Abstract: 3,3-Dialkyl- and 3-Alkyl-3-benzyl-Substituted 2-Pyrrolidinones: A New Class of Anticonvulsant Agents. Cheminform. 27: no-no. DOI: 10.1002/CHIN.199633131  0.061
2013 Rothman SM, Herdener N, Frankola KA, Mughal MR, Mattson MP. Chronic mild sleep restriction accentuates contextual memory impairments, and accumulations of cortical Aβ and pTau in a mouse model of Alzheimer's disease. Brain Research. 1529: 200-8. PMID 23856323 DOI: 10.1016/J.Brainres.2013.07.010  0.056
2011 Polgreen LE, Chahla S, Miller W, Rothman S, Tolar J, Kivisto T, Nascene D, Orchard PJ, Petryk A. Early diagnosis of cerebral X-linked adrenoleukodystrophy in boys with Addison's disease improves survival and neurological outcomes European Journal of Pediatrics. 170: 1049-1054. PMID 21279382 DOI: 10.1007/s00431-011-1401-1  0.054
2011 Rothman SM, Ma LH, Whiteside GT, Winkelstein BA. Inflammatory cytokine and chemokine expression is differentially modulated acutely in the dorsal root ganglion in response to different nerve root compressions. Spine. 36: 197-202. PMID 20714281 DOI: 10.1097/Brs.0B013E3181Ce4F4D  0.051
2004 Bale JF, Rothman SM. Pediatric neurology's midlife crisis [6] (multiple letters) Neurology. 63: 1342. PMID 15477579  0.048
2012 Rothman SM, Herdener N, Camandola S, Texel SJ, Mughal MR, Cong WN, Martin B, Mattson MP. 3xTgAD mice exhibit altered behavior and elevated Aβ after chronic mild social stress. Neurobiology of Aging. 33: 830.e1-12. PMID 21855175 DOI: 10.1016/J.Neurobiolaging.2011.07.005  0.048
2011 Miller WP, Rothman SM, Nascene D, Kivisto T, DeFor TE, Ziegler RS, Eisengart J, Leiser K, Raymond G, Lund TC, Tolar J, Orchard PJ. Outcomes after allogeneic hematopoietic cell transplantation for childhood cerebral adrenoleukodystrophy: the largest single-institution cohort report. Blood. 118: 1971-8. PMID 21586746 DOI: 10.1182/Blood-2011-01-329235  0.048
2014 Kawamoto EM, Cutler RG, Rothman SM, Mattson MP, Camandola S. TLR4-dependent metabolic changes are associated with cognitive impairment in an animal model of type 1 diabetes. Biochemical and Biophysical Research Communications. 443: 731-7. PMID 24342620 DOI: 10.1016/J.Bbrc.2013.12.039  0.048
2001 Alavi A, Chamberlain J, Cherrington AD, Convit A, Craft S, Cryer PE, Davis SN, Davison S, De Leon M, DeRosa M, Drucker D, Albert M, Evans M, Feldman E, Fischbach GD, ... ... Rothman SM, et al. Workshop on hypoglycemia and the brain Diabetes Technology and Therapeutics. 3: 469-516. DOI: 10.1089/15209150152607259  0.043
2013 Rothman SM, Brudney KF, Adair W, Rothman DJ. Medical communication companies and industry grants. Jama. 310: 2554-8. PMID 24346991 DOI: 10.1001/Jama.2013.281638  0.042
1981 Milbrandt JD, Heintz NH, White WC, Rothman SM, Hamlin JL. Methotrexate-resistant Chinese hamster ovary cells have amplified a 135-kilobase-pair region that includes the dihydrofolate reductase gene. Proceedings of the National Academy of Sciences of the United States of America. 78: 6043-7. PMID 6273843 DOI: 10.1073/pnas.78.10.6043  0.04
2012 Rothman SM, Mattson MP. Sleep disturbances in Alzheimer's and Parkinson's diseases. Neuromolecular Medicine. 14: 194-204. PMID 22552887 DOI: 10.1007/S12017-012-8181-2  0.037
2002 Rothman SM. Stroke in children: Freud's first analysis. Lancet. 360: 1526-7. PMID 12443585 DOI: 10.1016/S0140-6736(02)11576-5  0.037
2000 Butler RN, Fossel M, Pan CX, Rothman DJ, Rothman SM. Anti-aging medicine. 2. Efficacy and safety of hormones and antioxidants. Geriatrics. 55: 48-52, 55-6, 58. PMID 10909406  0.035
1980 Rothman DJ, Rothman SM. The conflict over children's rights. The Hastings Center Report. 10: 7-10. PMID 7204011 DOI: 10.2307/3560920  0.032
2011 Rothman SM, Raveis VH, Friedman A, Rothman DJ. Health advocacy organizations and the pharmaceutical industry: an analysis of disclosure practices. American Journal of Public Health. 101: 602-9. PMID 21233424 DOI: 10.2105/Ajph.2010.300027  0.032
2010 PETERSON EM, XU K, HOLLAND KD, MCKEON AC, ROTHMAN SM, FERRENDELLI JA, COVEY DF. ChemInform Abstract: α-Spirocyclopentyl- and α-Spirocyclopropyl-γ- butyrolactones: Conformationally Constrained Derivatives of Anticonvulsant and Convulsant α,α-Disubstituted γ- Butyrolactones. Cheminform. 25: no-no. DOI: 10.1002/chin.199420140  0.028
2006 Rothman SM, Rothman DJ. The hidden cost of organ sale. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. 6: 1524-8. PMID 16827852 DOI: 10.1111/J.1600-6143.2006.01325.X  0.028
2007 Macha M, Gupta D, Molina E, Palma J, Rothman S. Congenital heart disease manifested as acute abdominal pain. International Journal of Cardiology. 118: e92-3. PMID 17434625 DOI: 10.1016/j.ijcard.2007.01.039  0.026
2013 Rothman DJ, Rothman SM. When money talks. The Spine Journal : Official Journal of the North American Spine Society. 13: 998-1000. PMID 24029134 DOI: 10.1016/J.Spinee.2013.07.001  0.024
2012 Utz J, Ziegler R, Rothman S, Diethelm-Okita B, Whitley C. AIM, a Multi-Targeted, Combination Oral Therapy for the Gangliosidoses Molecular Genetics and Metabolism. 105: S61. DOI: 10.1016/J.Ymgme.2011.11.163  0.023
2007 Rothman SM, Rozario N, Rothman DJ. What body parts do we owe each other? Society. 44: 24-29. DOI: 10.1007/S12115-007-9004-1  0.023
2000 Butler RN, Fossel M, Pan CX, Rothman D, Rothman SM. Anti-aging medicine. What makes it different from geriatrics? Geriatrics. 55: 36, 39-43. PMID 10872344  0.022
2009 Rothman SM, Rothman DJ. Marketing HPV vaccine: implications for adolescent health and medical professionalism. Jama. 302: 781-6. PMID 19690311 DOI: 10.1001/Jama.2009.1179  0.02
2011 Smith JR, Rothman SM, Janmey PA, Winkelstein BA. Spinal PAR1 RNA levels are regulated by mechanical & inflammatory cues in painful nerve root compression Asme 2011 Summer Bioengineering Conference, Sbc 2011. 983-984. DOI: 10.1115/SBC2011-53084  0.017
1998 Rothman SM, Brenner P, Rouse F, Heywood J, Foley K. A community-based clinical selective in end-of-life care. Journal of Palliative Medicine. 1: 257-64. PMID 15859836 DOI: 10.1089/jpm.1998.1.257  0.016
2011 Rothman SM. Health advocacy organizations and evidence-based medicine. Jama. 305: 2569-70. PMID 21693747 DOI: 10.1001/jama.2011.866  0.014
2011 Rothman SM. Evidence-based practice and health advocacy organizations - Reply Jama - Journal of the American Medical Association. 306: 1444-1445. DOI: 10.1001/jama.2011.1406  0.014
2014 Rothman SM. Financial relationships between medical communication companies and industry--reply. Jama. 311: 1692-3. PMID 24756523 DOI: 10.1001/jama.2014.2331  0.013
2006 Brandt-Rauf SI, Raveis VH, Drummond NF, Conte JA, Rothman SM. Ashkenazi Jews and breast cancer: the consequences of linking ethnic identity to genetic disease. American Journal of Public Health. 96: 1979-88. PMID 17018815 DOI: 10.2105/AJPH.2005.083014  0.012
2016 Rothman SM, Alander SW. Neuroimaging Rates for Closed Head Trauma in a Community Hospital. Pediatric Emergency Care. PMID 27055166 DOI: 10.1097/PEC.0000000000000683  0.01
2009 Rothman SM, Rothman DJ. In reply Jama - Journal of the American Medical Association. 302: 261. DOI: 10.1001/Jama.2009.1887  0.01
1998 Simon MW, Simon NP, Rothman SM, Lee BCP. Bulging anterior fontanel Archives of Pediatrics and Adolescent Medicine. 152: 608. PMID 9641721  0.01
1998 Rothman SM, Lee BC. What bulges under a bulging fontanel? Archives of Pediatrics & Adolescent Medicine. 152: 100-1. PMID 9452720  0.01
1997 Rothman DJ, Rose E, Awaya T, Cohen B, Daar A, Dzemeshkevich SL, Lee CJ, Munro R, Reyes H, Rothman SM, Schoen KF, Scheper-Hughes N, Shapira Z, Smit H. The Bellagio Task Force report on transplantation, bodily integrity, and the International Traffic in Organs. Transplantation Proceedings. 29: 2739-45. PMID 9290810 DOI: 10.1016/S0041-1345(97)00577-0  0.01
1993 Rothman SM. Seek and hide: public health departments and persons with tuberculosis, 1890-1940. The Journal of Law, Medicine & Ethics : a Journal of the American Society of Law, Medicine & Ethics. 21: 289-95. PMID 8167803  0.01
1985 Rothman SM. Going public: historical perspectives on working women. American Journal of Psychoanalysis. 45: 167-75. PMID 4037154  0.01
1977 Rothman SM. Sterilizing the poor. Society. 14: 36-40. PMID 11661391 DOI: 10.1007/BF02695147  0.01
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