Adam J. Shaywitz, Ph.D. - Publications

Affiliations: 
2002 Harvard University, Cambridge, MA, United States 
Area:
Neuronal Transcription & Translation, Plasticity, Development, Synapse

16 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Jones SA, Bialer M, Parini R, Martin K, Wang H, Yang K, Shaywitz AJ, Harmatz P. Safety and clinical activity of elosulfase alfa in pediatric patients with Morquio A syndrome (mucopolysaccharidosis IVA) less than 5 years. Pediatric Research. PMID 26331768 DOI: 10.1038/pr.2015.169  0.84
2015 Body JJ, Bone HG, de Boer RH, Stopeck A, Van Poznak C, Damião R, Fizazi K, Henry DH, Ibrahim T, Lipton A, Saad F, Shore N, Takano T, Shaywitz AJ, Wang H, et al. Hypocalcaemia in patients with metastatic bone disease treated with denosumab. European Journal of Cancer (Oxford, England : 1990). PMID 26093811 DOI: 10.1016/j.ejca.2015.05.016  0.84
2015 Burton BK, Berger KI, Lewis GD, Tarnopolsky M, Treadwell M, Mitchell JJ, Muschol N, Jones SA, Sutton VR, Pastores GM, Lau H, Sparkes R, Genter F, Shaywitz AJ, Harmatz P. Safety and physiological effects of two different doses of elosulfase alfa in patients with morquio a syndrome: A randomized, double-blind, pilot study. American Journal of Medical Genetics. Part A. PMID 26069231 DOI: 10.1002/ajmg.a.37172  0.84
2015 Dias C, Abosaleem B, Crispino C, Gao B, Shaywitz A. Tolerability of High-Volume Subcutaneous Injections of a Viscous Placebo Buffer: A Randomized, Crossover Study in Healthy Subjects. Aaps Pharmscitech. PMID 25693652 DOI: 10.1208/s12249-015-0288-y  0.84
2015 Schweighardt B, Tompkins T, Lau K, Jesaitis L, Qi Y, Musson DG, Farmer P, Haller C, Shaywitz AJ, Yang K, O'Neill CA. Immunogenicity of Elosulfase Alfa, an Enzyme Replacement Therapy in Patients With Morquio A Syndrome: Results From MOR-004, a Phase III Trial. Clinical Therapeutics. 37: 1012-1021.e6. PMID 25487082 DOI: 10.1016/j.clinthera.2014.11.005  0.84
2014 Qi Y, Musson DG, Schweighardt B, Tompkins T, Jesaitis L, Shaywitz AJ, Yang K, O'Neill CA. Pharmacokinetic and pharmacodynamic evaluation of elosulfase alfa, an enzyme replacement therapy in patients with Morquio A syndrome. Clinical Pharmacokinetics. 53: 1137-47. PMID 25234648 DOI: 10.1007/s40262-014-0173-y  0.84
2014 Nelson OL, Jansen HT, Galbreath E, Morgenstern K, Gehring JL, Rigano KS, Lee J, Gong J, Shaywitz AJ, Vella CA, Robbins CT, Corbit KC. Grizzly bears exhibit augmented insulin sensitivity while obese prior to a reversible insulin resistance during hibernation. Cell Metabolism. 20: 376-82. PMID 25100064 DOI: 10.1016/j.cmet.2014.07.008  0.84
2013 Wu N, Zheng B, Shaywitz A, Dagon Y, Tower C, Bellinger G, Shen CH, Wen J, Asara J, McGraw TE, Kahn BB, Cantley LC. AMPK-dependent degradation of TXNIP upon energy stress leads to enhanced glucose uptake via GLUT1. Molecular Cell. 49: 1167-75. PMID 23453806 DOI: 10.1016/j.molcel.2013.01.035  0.84
2012 Dias CS, Shaywitz AJ, Wasserman SM, Smith BP, Gao B, Stolman DS, Crispino CP, Smirnakis KV, Emery MG, Colbert A, Gibbs JP, Retter MW, Cooke BP, Uy ST, Matson M, et al. Effects of AMG 145 on low-density lipoprotein cholesterol levels: results from 2 randomized, double-blind, placebo-controlled, ascending-dose phase 1 studies in healthy volunteers and hypercholesterolemic subjects on statins. Journal of the American College of Cardiology. 60: 1888-98. PMID 23083772 DOI: 10.1016/j.jacc.2012.08.986  0.84
2008 Shaywitz AJ, Courtney KD, Patnaik A, Cantley LC. PI3K enters beta-testing. Cell Metabolism. 8: 179-81. PMID 18762017 DOI: 10.1016/j.cmet.2008.08.011  0.84
2002 Shaywitz AJ, Dove SL, Greenberg ME, Hochschild A. Analysis of phosphorylation-dependent protein-protein interactions using a bacterial two-hybrid system. Science's Stke : Signal Transduction Knowledge Environment. 2002: pl11. PMID 12138210 DOI: 10.1126/stke.2002.142.pl11  0.84
2002 Kornhauser JM, Cowan CW, Shaywitz AJ, Dolmetsch RE, Griffith EC, Hu LS, Haddad C, Xia Z, Greenberg ME. CREB transcriptional activity in neurons is regulated by multiple, calcium-specific phosphorylation events. Neuron. 34: 221-33. PMID 11970864 DOI: 10.1016/S0896-6273(02)00655-4  0.84
2001 West AE, Chen WG, Dalva MB, Dolmetsch RE, Kornhauser JM, Shaywitz AJ, Takasu MA, Tao X, Greenberg ME. Calcium regulation of neuronal gene expression. Proceedings of the National Academy of Sciences of the United States of America. 98: 11024-31. PMID 11572963 DOI: 10.1073/pnas.191352298  0.84
2000 Shaywitz AJ, Dove SL, Kornhauser JM, Hochschild A, Greenberg ME. Magnitude of the CREB-dependent transcriptional response is determined by the strength of the interaction between the kinase-inducible domain of CREB and the KIX domain of CREB-binding protein. Molecular and Cellular Biology. 20: 9409-22. PMID 11094091 DOI: 10.1128/MCB.20.24.9409-9422.2000  0.84
1999 Shaywitz AJ, Greenberg ME. CREB: a stimulus-induced transcription factor activated by a diverse array of extracellular signals. Annual Review of Biochemistry. 68: 821-61. PMID 10872467 DOI: 10.1146/annurev.biochem.68.1.821  0.84
1998 Tao X, Finkbeiner S, Arnold DB, Shaywitz AJ, Greenberg ME. Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism. Neuron. 20: 709-26. PMID 9581763 DOI: 10.1016/S0896-6273(00)81010-7  0.84
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