Zhengui Xia - Publications

Affiliations: 
Toxicology University of Washington, Seattle, Seattle, WA 
Area:
Neuronal Apoptosis and stem cell biology

62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Wang H, Abel GM, Storm DR, Xia Z. Cadmium Exposure Impairs Adult Hippocampal Neurogenesis. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 31271426 DOI: 10.1093/toxsci/kfz152  0.76
2019 Zhang L, Chen X, Sindreu C, Lu S, Storm DR, Zweifel LS, Xia Z. Dynamics of a hippocampal neuronal ensemble encoding trace fear memory revealed by in vivo Ca2+ imaging. Plos One. 14: e0219152. PMID 31269057 DOI: 10.1371/journal.pone.0219152  0.76
2018 Giurisato E, Xu Q, Lonardi S, Telfer B, Russo I, Pearson A, Finegan KG, Wang W, Wang J, Gray NS, Vermi W, Xia Z, Tournier C. Myeloid ERK5 deficiency suppresses tumor growth by blocking protumor macrophage polarization via STAT3 inhibition. Proceedings of the National Academy of Sciences of the United States of America. PMID 29507229 DOI: 10.1073/pnas.1707929115  0.72
2017 Engstrom AK, Snyder JM, Maeda N, Xia Z. Correction to: Gene-environment interaction between lead and Apolipoprotein E4 causes cognitive behavior deficits in mice. Molecular Neurodegeneration. 12: 81. PMID 29100536 DOI: 10.1186/s13024-017-0223-7  0.72
2017 Wang H, Zhang L, Abel GM, Storm DR, Xia Z. Cadmium exposure impairs cognition and olfactory memory in male C57BL/6 mice. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 29029324 DOI: 10.1093/toxsci/kfx202  0.76
2017 Engstrom AK, Xia Z. Lead exposure in late adolescence through adulthood impairs short-term spatial memory and the neuronal differentiation of adult-born cells in C57BL/6 male mice. Neuroscience Letters. PMID 28970130 DOI: 10.1016/j.neulet.2017.09.060  0.72
2017 Choi WS, Kim HW, Tronche F, Palmiter RD, Storm DR, Xia Z. Conditional deletion of Ndufs4 in dopaminergic neurons promotes Parkinson's disease-like non-motor symptoms without loss of dopamine neurons. Scientific Reports. 7: 44989. PMID 28327638 DOI: 10.1038/srep44989  0.76
2017 Engstrom AK, Snyder JM, Maeda N, Xia Z. Gene-environment interaction between lead and Apolipoprotein E4 causes cognitive behavior deficits in mice. Molecular Neurodegeneration. 12: 14. PMID 28173832 DOI: 10.1186/s13024-017-0155-2  0.72
2017 Wang H, Engstrom AK, Xia Z. Cadmium impairs the survival and proliferation of cultured adult subventricular neural stem cells through activation of the JNK and p38 MAP kinases. Toxicology. PMID 28163110 DOI: 10.1016/j.tox.2017.01.013  0.76
2015 Zou J, Wang W, Pan YW, Abel GM, Storm DR, Xia Z. Conditional Inhibition of Adult Neurogenesis by Inducible and Targeted Deletion of ERK5 MAP Kinase Is Not Associated with Anxiety/Depression-Like Behaviors(1,2). Eneuro. 2. PMID 26464972 DOI: 10.1523/ENEURO.0014-14.2015  0.76
2015 Kim HW, Choi WS, Sorscher N, Park HJ, Tronche F, Palmiter RD, Xia Z. Genetic reduction of mitochondrial complex I function does not lead to loss of dopamine neurons in vivo. Neurobiology of Aging. PMID 26070241 DOI: 10.1016/j.neurobiolaging.2015.05.008  1
2015 Wang W, Lu S, Li T, Pan YW, Zou J, Abel GM, Xu L, Storm DR, Xia Z. Inducible activation of ERK5 MAP kinase enhances adult neurogenesis in the olfactory bulb and improves olfactory function. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 7833-49. PMID 25995470 DOI: 10.1523/JNEUROSCI.3745-14.2015  1
2015 Engstrom A, Wang H, Xia Z. Lead decreases cell survival, proliferation, and neuronal differentiation of primary cultured adult neural precursor cells through activation of the JNK and p38 MAP kinases. Toxicology in Vitro : An International Journal Published in Association With Bibra. 29: 1146-55. PMID 25967738 DOI: 10.1016/j.tiv.2015.05.001  0.76
2015 Luo J, Chen X, Pan YW, Lu S, Xia Z, Storm DR. The type 3 adenylyl cyclase is required for the survival and maturation of newly generated granule cells in the olfactory bulb. Plos One. 10: e0122057. PMID 25807252 DOI: 10.1371/journal.pone.0122057  1
2015 Yu AK, Song L, Murray KD, van der List D, Sun C, Shen Y, Xia Z, Cortopassi GA. Mitochondrial complex I deficiency leads to inflammation and retinal ganglion cell death in the Ndufs4 mouse. Human Molecular Genetics. 24: 2848-60. PMID 25652399 DOI: 10.1093/hmg/ddv045  0.44
2015 Zou J, Wang W, Pan YW, Lu S, Xia Z. Methods to measure olfactory behavior in mice. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. 63: 11.18.1-11.18.21. PMID 25645244 DOI: 10.1002/0471140856.tx1118s63  1
2015 Choi WS, Kim HW, Xia Z. JNK inhibition of VMAT2 contributes to rotenone-induced oxidative stress and dopamine neuron death. Toxicology. 328: 75-81. PMID 25496994 DOI: 10.1016/j.tox.2014.12.005  1
2014 Choi WS, Xia Z. Maneb-induced dopaminergic neuronal death is not affected by loss of mitochondrial complex I activity: results from primary mesencephalic dopaminergic neurons cultured from individual Ndufs4+/+ and Ndufs4-/- mouse embryos. Neuroreport. 25: 1350-5. PMID 25275677 DOI: 10.1097/WNR.0000000000000271  0.52
2014 Wang W, Pan YW, Zou J, Li T, Abel GM, Palmiter RD, Storm DR, Xia Z. Genetic activation of ERK5 MAP kinase enhances adult neurogenesis and extends hippocampus-dependent long-term memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 2130-47. PMID 24501354 DOI: 10.1523/JNEUROSCI.3324-13.2014  1
2013 Chen X, Xia Z, Storm DR. Electroolfactogram (EOG) Recording in the Mouse Main Olfactory Epithelium. Bio-Protocol. 3. PMID 27430002  0.76
2013 Zou J, Storm DR, Xia Z. Conditional deletion of ERK5 MAP kinase in the nervous system impairs pheromone information processing and pheromone-evoked behaviors. Plos One. 8: e76901. PMID 24130808 DOI: 10.1371/journal.pone.0076901  1
2013 Pan YW, Storm DR, Xia Z. Role of adult neurogenesis in hippocampus-dependent memory, contextual fear extinction and remote contextual memory: new insights from ERK5 MAP kinase. Neurobiology of Learning and Memory. 105: 81-92. PMID 23871742 DOI: 10.1016/j.nlm.2013.07.011  1
2013 Choi WS, Kim HW, Xia Z. Preparation of primary cultured dopaminergic neurons from mouse brain. Methods in Molecular Biology (Clifton, N.J.). 1018: 61-9. PMID 23681617 DOI: 10.1007/978-1-62703-444-9_6  0.52
2013 Pan YW, Wang W, Xia Z. Assessment of adult neurogenesis in mice. Current Protocols in Toxicology / Editorial Board, Mahin D. Maines (Editor-in-Chief) ... [Et Al.]. Unit12.20. PMID 23670864 DOI: 10.1002/0471140856.tx1220s56  1
2013 Li T, Pan YW, Wang W, Abel G, Zou J, Xu L, Storm DR, Xia Z. Targeted deletion of the ERK5 MAP kinase impairs neuronal differentiation, migration, and survival during adult neurogenesis in the olfactory bulb. Plos One. 8: e61948. PMID 23630619 DOI: 10.1371/journal.pone.0061948  1
2013 Li T, Wang W, Pan YW, Xu L, Xia Z. A hydroxylated metabolite of flame-retardant PBDE-47 decreases the survival, proliferation, and neuronal differentiation of primary cultured adult neural stem cells and interferes with signaling of ERK5 MAP kinase and neurotrophin 3. Toxicological Sciences : An Official Journal of the Society of Toxicology. 134: 111-24. PMID 23564643 DOI: 10.1093/toxsci/kft083  1
2013 Wang W, Pan YW, Wietecha T, Zou J, Abel GM, Kuo CT, Xia Z. Extracellular signal-regulated kinase 5 (ERK5) mediates prolactin-stimulated adult neurogenesis in the subventricular zone and olfactory bulb. The Journal of Biological Chemistry. 288: 2623-31. PMID 23223235 DOI: 10.1074/jbc.M112.401091  1
2012 Pan YW, Storm DR, Xia Z. The maintenance of established remote contextual fear memory requires ERK5 MAP kinase and ongoing adult neurogenesis in the hippocampus. Plos One. 7: e50455. PMID 23189204 DOI: 10.1371/journal.pone.0050455  1
2012 Pan YW, Kuo CT, Storm DR, Xia Z. Inducible and targeted deletion of the ERK5 MAP kinase in adult neurogenic regions impairs adult neurogenesis in the olfactory bulb and several forms of olfactory behavior. Plos One. 7: e49622. PMID 23185386 DOI: 10.1371/journal.pone.0049622  1
2012 Chen X, Xia Z, Storm DR. Stimulation of electro-olfactogram responses in the main olfactory epithelia by airflow depends on the type 3 adenylyl cyclase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 15769-78. PMID 23136416 DOI: 10.1523/JNEUROSCI.2180-12.2012  1
2012 Xia Z, Storm DR. Role of signal transduction crosstalk between adenylyl cyclase and MAP kinase in hippocampus-dependent memory. Learning & Memory (Cold Spring Harbor, N.Y.). 19: 369-74. PMID 22904367 DOI: 10.1101/lm.027128.112  1
2012 Pan YW, Zou J, Wang W, Sakagami H, Garelick MG, Abel G, Kuo CT, Storm DR, Xia Z. Inducible and conditional deletion of extracellular signal-regulated kinase 5 disrupts adult hippocampal neurogenesis. The Journal of Biological Chemistry. 287: 23306-17. PMID 22645146 DOI: 10.1074/jbc.M112.344762  1
2012 Pan YW, Chan GC, Kuo CT, Storm DR, Xia Z. Inhibition of adult neurogenesis by inducible and targeted deletion of ERK5 mitogen-activated protein kinase specifically in adult neurogenic regions impairs contextual fear extinction and remote fear memory. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6444-55. PMID 22573667 DOI: 10.1523/JNEUROSCI.6076-11.2012  1
2012 Zou J, Pan YW, Wang Z, Chang SY, Wang W, Wang X, Tournier C, Storm DR, Xia Z. Targeted deletion of ERK5 MAP kinase in the developing nervous system impairs development of GABAergic interneurons in the main olfactory bulb and behavioral discrimination between structurally similar odorants. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 4118-32. PMID 22442076 DOI: 10.1523/JNEUROSCI.6260-11.2012  1
2011 Choi WS, Klintworth HM, Xia Z. JNK3-mediated apoptotic cell death in primary dopaminergic neurons. Methods in Molecular Biology (Clifton, N.J.). 758: 279-92. PMID 21815073 DOI: 10.1007/978-1-61779-170-3_19  1
2011 Choi WS, Palmiter RD, Xia Z. Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model. The Journal of Cell Biology. 192: 873-82. PMID 21383081 DOI: 10.1083/jcb.201009132  1
2010 Choi WS, Abel G, Klintworth H, Flavell RA, Xia Z. JNK3 mediates paraquat- and rotenone-induced dopaminergic neuron death. Journal of Neuropathology and Experimental Neurology. 69: 511-20. PMID 20418776 DOI: 10.1097/NEN.0b013e3181db8100  1
2009 Wang Z, Li V, Chan GC, Phan T, Nudelman AS, Xia Z, Storm DR. Adult type 3 adenylyl cyclase-deficient mice are obese. Plos One. 4: e6979. PMID 19750222 DOI: 10.1371/journal.pone.0006979  1
2009 Klintworth H, Garden G, Xia Z. Rotenone and paraquat do not directly activate microglia or induce inflammatory cytokine release. Neuroscience Letters. 462: 1-5. PMID 19559752 DOI: 10.1016/j.neulet.2009.06.065  1
2009 Cundiff P, Liu L, Wang Y, Zou J, Pan YW, Abel G, Duan X, Ming GL, Englund C, Hevner R, Xia Z. ERK5 MAP kinase regulates neurogenin1 during cortical neurogenesis. Plos One. 4: e5204. PMID 19365559 DOI: 10.1371/journal.pone.0005204  1
2008 Choi WS, Kruse SE, Palmiter RD, Xia Z. Mitochondrial complex I inhibition is not required for dopaminergic neuron death induced by rotenone, MPP+, or paraquat. Proceedings of the National Academy of Sciences of the United States of America. 105: 15136-41. PMID 18812510 DOI: 10.1073/pnas.0807581105  1
2008 Faigle R, Liu L, Cundiff P, Funa K, Xia Z. Opposing effects of retinoid signaling on astrogliogenesis in embryonic day 13 and 17 cortical progenitor cells. Journal of Neurochemistry. 106: 1681-98. PMID 18564368 DOI: 10.1111/j.1471-4159.2008.05525.x  0.96
2008 Cai B, Xia Z. p38 MAP kinase mediates arsenite-induced apoptosis through FOXO3a activation and induction of Bim transcription. Apoptosis : An International Journal On Programmed Cell Death. 13: 803-10. PMID 18465250 DOI: 10.1007/s10495-008-0218-5  1
2007 Wang Y, Liu L, Xia Z. Brain-derived neurotrophic factor stimulates the transcriptional and neuroprotective activity of myocyte-enhancer factor 2C through an ERK1/2-RSK2 signaling cascade. Journal of Neurochemistry. 102: 957-66. PMID 17630987 DOI: 10.1111/j.1471-4159.2007.04606.x  1
2007 Cude K, Wang Y, Choi HJ, Hsuan SL, Zhang H, Wang CY, Xia Z. Regulation of the G2-M cell cycle progression by the ERK5-NFkappaB signaling pathway. The Journal of Cell Biology. 177: 253-64. PMID 17452529 DOI: 10.1083/jcb.200609166  1
2007 Klintworth H, Newhouse K, Li T, Choi WS, Faigle R, Xia Z. Activation of c-Jun N-terminal protein kinase is a common mechanism underlying paraquat- and rotenone-induced dopaminergic cell apoptosis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 97: 149-62. PMID 17324951 DOI: 10.1093/toxsci/kfm029  1
2006 Wang Y, Su B, Xia Z. Brain-derived neurotrophic factor activates ERK5 in cortical neurons via a Rap1-MEKK2 signaling cascade. The Journal of Biological Chemistry. 281: 35965-74. PMID 17003042 DOI: 10.1074/jbc.M605503200  1
2006 Cai B, Chang SH, Becker EB, Bonni A, Xia Z. p38 MAP kinase mediates apoptosis through phosphorylation of BimEL at Ser-65. The Journal of Biological Chemistry. 281: 25215-22. PMID 16818494 DOI: 10.1074/jbc.M512627200  1
2006 Liu L, Cundiff P, Abel G, Wang Y, Faigle R, Sakagami H, Xu M, Xia Z. Extracellular signal-regulated kinase (ERK) 5 is necessary and sufficient to specify cortical neuronal fate. Proceedings of the National Academy of Sciences of the United States of America. 103: 9697-702. PMID 16766652 DOI: 10.1073/pnas.0603373103  1
2006 Hsuan SL, Klintworth HM, Xia Z. Basic fibroblast growth factor protects against rotenone-induced dopaminergic cell death through activation of extracellular signal-regulated kinases 1/2 and phosphatidylinositol-3 kinase pathways. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 4481-91. PMID 16641227 DOI: 10.1523/JNEUROSCI.4922-05.2006  1
2005 Tang X, Wang X, Gong X, Tong M, Park D, Xia Z, Mao Z. Cyclin-dependent kinase 5 mediates neurotoxin-induced degradation of the transcription factor myocyte enhancer factor 2. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 4823-34. PMID 15888658 DOI: 10.1523/JNEUROSCI.1331-05.2005  1
2005 Xia Z, Storm DR. The role of calmodulin as a signal integrator for synaptic plasticity. Nature Reviews. Neuroscience. 6: 267-76. PMID 15803158 DOI: 10.1038/nrn1647  1
2004 Chang SH, Poser S, Xia Z. A novel role for serum response factor in neuronal survival. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 24: 2277-85. PMID 14999078 DOI: 10.1523/JNEUROSCI.4868-03.2004  1
2004 Newhouse K, Hsuan SL, Chang SH, Cai B, Wang Y, Xia Z. Rotenone-induced apoptosis is mediated by p38 and JNK MAP kinases in human dopaminergic SH-SY5Y cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 79: 137-46. PMID 14976342 DOI: 10.1093/toxsci/kfh089  1
2004 Caughlan A, Newhouse K, Namgung U, Xia Z. Chlorpyrifos induces apoptosis in rat cortical neurons that is regulated by a balance between p38 and ERK/JNK MAP kinases. Toxicological Sciences : An Official Journal of the Society of Toxicology. 78: 125-34. PMID 14691213 DOI: 10.1093/toxsci/kfh038  0.76
2003 Liu L, Cavanaugh JE, Wang Y, Sakagami H, Mao Z, Xia Z. ERK5 activation of MEF2-mediated gene expression plays a critical role in BDNF-promoted survival of developing but not mature cortical neurons. Proceedings of the National Academy of Sciences of the United States of America. 100: 8532-7. PMID 12826611 DOI: 10.1073/pnas.1332804100  1
2003 Poser S, Impey S, Xia Z, Storm DR. Brain-derived neurotrophic factor protection of cortical neurons from serum withdrawal-induced apoptosis is inhibited by cAMP. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 4420-7. PMID 12805282  1
2002 Hetman M, Hsuan SL, Habas A, Higgins MJ, Xia Z. ERK1/2 antagonizes glycogen synthase kinase-3beta-induced apoptosis in cortical neurons. The Journal of Biological Chemistry. 277: 49577-84. PMID 12393899 DOI: 10.1074/jbc.M111227200  1
2002 Ghahremani MH, Keramaris E, Shree T, Xia Z, Davis RJ, Flavell R, Slack RS, Park DS. Interaction of the c-Jun/JNK pathway and cyclin-dependent kinases in death of embryonic cortical neurons evoked by DNA damage. The Journal of Biological Chemistry. 277: 35586-96. PMID 12091388 DOI: 10.1074/jbc.M204362200  1
2002 Kornhauser JM, Cowan CW, Shaywitz AJ, Dolmetsch RE, Griffith EC, Hu LS, Haddad C, Xia Z, Greenberg ME. CREB transcriptional activity in neurons is regulated by multiple, calcium-specific phosphorylation events. Neuron. 34: 221-33. PMID 11970864 DOI: 10.1016/S0896-6273(02)00655-4  1
2002 Zhu Y, Mao XO, Sun Y, Xia Z, Greenberg DA. p38 Mitogen-activated protein kinase mediates hypoxic regulation of Mdm2 and p53 in neurons. The Journal of Biological Chemistry. 277: 22909-14. PMID 11948180 DOI: 10.1074/jbc.M200042200  0.32
2002 Xia Z, Storm DR. CaRF: a neuronal transcription factor that CaREs. Neuron. 33: 315-6. PMID 11832218 DOI: 10.1016/S0896-6273(02)00578-0  1
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