Dennis Clegg - Publications

Affiliations: 
University of California, Santa Barbara, Santa Barbara, CA, United States 

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Dang W, Lin CM, Mitra D, Zhu D, Thomas BB, Hikita ST, Pennington BO, Johnson LV, Clegg DO, Hinton DR, et al. A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration. Science Translational Medicine. 10. PMID 29618560 DOI: 10.1126/scitranslmed.aao4097  0.84
2016 Leach LL, Croze RH, Hu Q, Nadar VP, Clevenger TN, Pennington BO, Gamm DM, Clegg DO. Induced Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium: A Comparative Study Between Cell Lines and Differentiation Methods. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. PMID 27182743 DOI: 10.1089/jop.2016.0022  0.36
2016 Clevenger TN, Hinman CR, Ashley Rubin RK, Smither K, Burke DJ, Hawker CJ, Messina D, van Epps D, Clegg DO. Vitronectin-based, biomimetic encapsulating hydrogel scaffolds support adipogenesis of adipose stem cells. Tissue Engineering. Part A. PMID 26956095 DOI: 10.1089/ten.TEA.2015.0550  0.84
2016 Pennington BO, Clegg DO. Pluripotent Stem Cell-Based Therapies in Combination with Substrate for the Treatment of Age-Related Macular Degeneration. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. PMID 26889704 DOI: 10.1089/jop.2015.0153  0.36
2015 Nazari H, Zhang L, Zhu D, Chader GJ, Falabella P, Stefanini F, Rawland T, Clegg DO, Kashani AH, Hinton DR, Humayun MS. Stem cell based therapies for age-related macular degeneration: the promises and the challenges. Progress in Retinal and Eye Research. PMID 26113213 DOI: 10.1016/j.preteyeres.2015.06.004  0.84
2015 Forest DL, Johnson LV, Clegg DO. Cellular models and therapies for age-related macular degeneration. Disease Models & Mechanisms. 8: 421-7. PMID 26035859 DOI: 10.1242/dmm.017236  0.44
2015 Leach LL, Clegg DO. Concise Review: Making Stem Cells Retinal: Methods for Deriving Retinal Pigment Epithelium and Implications for Patients With Ocular Disease. Stem Cells (Dayton, Ohio). 33: 2363-73. PMID 25809736 DOI: 10.1002/stem.2010  0.84
2015 Leach LL, Buchholz DE, Nadar VP, Lowenstein SE, Clegg DO. Canonical/β-catenin Wnt pathway activation improves retinal pigmented epithelium derivation from human embryonic stem cells. Investigative Ophthalmology & Visual Science. 56: 1002-13. PMID 25604686 DOI: 10.1167/iovs.14-15835  0.76
2015 Pennington BO, Clegg DO, Melkoumian ZK, Hikita ST. Defined culture of human embryonic stem cells and xeno-free derivation of retinal pigmented epithelial cells on a novel, synthetic substrate. Stem Cells Translational Medicine. 4: 165-77. PMID 25593208 DOI: 10.5966/sctm.2014-0179  0.84
2014 Pennington BO, Sears D, Clegg DO. Interactive Hangman teaches amino acid structures and abbreviations. Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology. 42: 495-500. PMID 25345852 DOI: 10.1002/bmb.20826  0.84
2014 Hu Q, Chen R, Teesalu T, Ruoslahti E, Clegg DO. Reprogramming human retinal pigmented epithelial cells to neurons using recombinant proteins. Stem Cells Translational Medicine. 3: 1526-34. PMID 25298373 DOI: 10.5966/sctm.2014-0038  0.84
2014 Croze RH, Buchholz DE, Radeke MJ, Thi WJ, Hu Q, Coffey PJ, Clegg DO. ROCK Inhibition Extends Passage of Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium. Stem Cells Translational Medicine. 3: 1066-78. PMID 25069775 DOI: 10.5966/sctm.2014-0079  0.84
2014 Croze RH, Clegg DO. Differentiation of pluripotent stem cells into retinal pigmented epithelium. Developments in Ophthalmology. 53: 81-96. PMID 24732763 DOI: 10.1159/000357361  0.84
2013 Buchholz DE, Pennington BO, Croze RH, Hinman CR, Coffey PJ, Clegg DO. Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium. Stem Cells Translational Medicine. 2: 384-93. PMID 23599499 DOI: 10.5966/sctm.2012-0163  0.84
2013 Rowland TJ, Blaschke AJ, Buchholz DE, Hikita ST, Johnson LV, Clegg DO. Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins. Journal of Tissue Engineering and Regenerative Medicine. 7: 642-53. PMID 22514096 DOI: 10.1002/term.1458  0.84
2012 Hu Y, Liu L, Lu B, Zhu D, Ribeiro R, Diniz B, Thomas PB, Ahuja AK, Hinton DR, Tai YC, Hikita ST, Johnson LV, Clegg DO, Thomas BB, Humayun MS. A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer. Ophthalmic Research. 48: 186-91. PMID 22868580 DOI: 10.1159/000338749  0.84
2012 Rowland TJ, Buchholz DE, Clegg DO. Pluripotent human stem cells for the treatment of retinal disease. Journal of Cellular Physiology. 227: 457-66. PMID 21520078 DOI: 10.1002/jcp.22814  0.84
2010 Gupta N, Lin BF, Campos LM, Dimitriou MD, Hikita ST, Treat ND, Tirrell MV, Clegg DO, Kramer EJ, Hawker CJ. A versatile approach to high-throughput microarrays using thiol-ene chemistry. Nature Chemistry. 2: 138-45. PMID 21124405 DOI: 10.1038/nchem.478  0.84
2010 Neveu P, Kye MJ, Qi S, Buchholz DE, Clegg DO, Sahin M, Park IH, Kim KS, Daley GQ, Kornblum HI, Shraiman BI, Kosik KS. MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states. Cell Stem Cell. 7: 671-81. PMID 21112562 DOI: 10.1016/j.stem.2010.11.012  0.84
2010 Hu Q, Friedrich AM, Johnson LV, Clegg DO. Memory in induced pluripotent stem cells: reprogrammed human retinal-pigmented epithelial cells show tendency for spontaneous redifferentiation. Stem Cells (Dayton, Ohio). 28: 1981-91. PMID 20882530 DOI: 10.1002/stem.531  0.84
2010 Kolhar P, Kotamraju VR, Hikita ST, Clegg DO, Ruoslahti E. Synthetic surfaces for human embryonic stem cell culture. Journal of Biotechnology. 146: 143-6. PMID 20132848 DOI: 10.1016/j.jbiotec.2010.01.016  0.84
2010 Rowland TJ, Miller LM, Blaschke AJ, Doss EL, Bonham AJ, Hikita ST, Johnson LV, Clegg DO. Roles of integrins in human induced pluripotent stem cell growth on Matrigel and vitronectin. Stem Cells and Development. 19: 1231-40. PMID 19811096 DOI: 10.1089/scd.2009.0328  0.84
2009 Carr AJ, Vugler AA, Hikita ST, Lawrence JM, Gias C, Chen LL, Buchholz DE, Ahmado A, Semo M, Smart MJ, Hasan S, da Cruz L, Johnson LV, Clegg DO, Coffey PJ. Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat. Plos One. 4: e8152. PMID 19997644 DOI: 10.1371/journal.pone.0008152  0.84
2009 Buchholz DE, Hikita ST, Rowland TJ, Friedrich AM, Hinman CR, Johnson LV, Clegg DO. Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells. Stem Cells (Dayton, Ohio). 27: 2427-34. PMID 19658190 DOI: 10.1002/stem.189  0.84
2008 Hikita ST, Kosik KS, Clegg DO, Bamdad C. MUC1* mediates the growth of human pluripotent stem cells. Plos One. 3: e3312. PMID 18833326 DOI: 10.1371/journal.pone.0003312  0.84
2007 Dunkle ET, Zaucke F, Clegg DO. Thrombospondin-4 and matrix three-dimensionality in axon outgrowth and adhesion in the developing retina. Experimental Eye Research. 84: 707-17. PMID 17320079 DOI: 10.1016/j.exer.2006.12.014  0.84
2006 Hikita ST, Vistica BP, Jones HR, Keswani JR, Watson MM, Ericson VR, Ayoub GS, Gery I, Clegg DO. Osteopontin is proinflammatory in experimental autoimmune uveitis. Investigative Ophthalmology & Visual Science. 47: 4435-43. PMID 17003437 DOI: 10.1167/iovs.06-0064  0.84
2005 Wingerd KL, Wayne WC, Jackson DY, Clegg DO. Involvement of alpha4 integrins in maintenance of cardiac sympathetic axons. Autonomic Neuroscience : Basic & Clinical. 122: 58-68. PMID 16181811 DOI: 10.1016/j.autneu.2005.08.006  0.84
2005 Putzke AP, Hikita ST, Clegg DO, Rothman JH. Essential kinase-independent role of a Fer-like non-receptor tyrosine kinase in Caenorhabditis elegans morphogenesis. Development (Cambridge, England). 132: 3185-95. PMID 15958510 DOI: 10.1242/dev.01900  0.84
2004 Leu ST, Jacques SA, Wingerd KL, Hikita ST, Tolhurst EC, Pring JL, Wiswell D, Kinney L, Goodman NL, Jackson DY, Clegg DO. Integrin alpha4beta1 function is required for cell survival in developing retina. Developmental Biology. 276: 416-30. PMID 15581875 DOI: 10.1016/j.ydbio.2004.09.003  0.84
2004 Wingerd KL, Goodman NL, Leu ST, Clegg DO. Expression and function of integrin alpha4beta1 and vascular cell adhesion molecule-1 (VCAM-1) during sympathetic innervation of the heart. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 231: 359-69. PMID 15366013 DOI: 10.1002/dvdy.20120  0.84
2003 Hikita ST, Cann GM, Wingerd KL, Mullick LH, Wayne WC, Webb SW, Clegg DO. Integrin alpha4beta1 (VLA-4) expression and activity in retinal and peripheral neurons. Molecular and Cellular Neurosciences. 23: 427-39. PMID 12837626 DOI: 10.1016/S1044-7431(03)00065-4  0.84
2003 Clegg DO, Wingerd KL, Hikita ST, Tolhurst EC. Integrins in the development, function and dysfunction of the nervous system. Frontiers in Bioscience : a Journal and Virtual Library. 8: d723-50. PMID 12700040  0.84
2002 Wingerd KL, Goodman NL, Tresser JW, Smail MM, Leu ST, Rohan SJ, Pring JL, Jackson DY, Clegg DO. Alpha 4 integrins and vascular cell adhesion molecule-1 play a role in sympathetic innervation of the heart. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10772-80. PMID 12486170  0.84
2002 Hansma HG, Clegg DO, Kokkoli E, Oroudjev E, Tirrell M. Analysis of matrix dynamics by atomic force microscopy. Methods in Cell Biology. 69: 163-93. PMID 12070991 DOI: 10.1016/S0091-679X(02)69012-0  0.84
2002 Mey A, Gandrillon O, McNagny KM, Clegg DO, Samarut J. The v-erbA oncogene blocks expression of alpha2/beta1 integrin a normal inhibitor of erythroid progenitor proliferation. Oncogene. 21: 2864-72. PMID 11973646 DOI: 10.1038/sj.onc.1205411  0.84
2002 Leu ST, Batni S, Radeke MJ, Johnson LV, Anderson DH, Clegg DO. Drusen are Cold Spots for Proteolysis: Expression of Matrix Metalloproteinases and Their Tissue Inhibitor Proteins in Age-related Macular Degeneration. Experimental Eye Research. 74: 141-54. PMID 11878827 DOI: 10.1006/exer.2001.1112  0.84
2001 Culley B, Murphy J, Babaie J, Nguyen D, Pagel A, Rousselle P, Clegg DO. Laminin-5 promotes neurite outgrowth from central and peripheral chick embryonic neurons Neuroscience Letters. 301: 83-86. PMID 11248428 DOI: 10.1016/S0304-3940(01)01615-9  0.84
2001 Leonoudakis D, Mailliard W, Wingerd K, Clegg D, Vandenberg C. Inward rectifier potassium channel Kir2.2 is associated with synapse-associated protein SAP97. Journal of Cell Science. 114: 987-98. PMID 11181181  0.84
2000 Clegg DO, Mullick LH, Wingerd KL, Lin H, Atienza JW, Bradshaw AD, Gervin DB, Cann GM. Adhesive events in retinal development and function: the role of integrin receptors. Results and Problems in Cell Differentiation. 31: 141-56. PMID 10929405  0.84
2000 Lin H, Lal R, Clegg DO. Imaging and mapping heparin-binding sites on single fibronectin molecules with atomic force microscopy Biochemistry. 39: 3192-3196. PMID 10727210 DOI: 10.1021/bi991624o  0.84
2000 Clegg DO. Novel roles for integrins in the nervous system Molecular Cell Biology Research Communications. 3: 1-7. PMID 10683310 DOI: 10.1006/mcbr.1999.0175  0.84
1999 Lin H, Clegg DO, Lal R. Imaging real-time proteolysis of single collagen I molecules with an atomic force microscope Biochemistry. 38: 9956-9963. PMID 10433702 DOI: 10.1021/bi990800q  0.84
1998 Kil SH, Krull CE, Cann G, Clegg D, Bronner-Fraser M. The alpha4 subunit of integrin is important for neural crest cell migration. Developmental Biology. 202: 29-42. PMID 9758701 DOI: 10.1006/dbio.1998.8985  0.84
1998 Lin H, Clegg DO. Integrin αvβ5 participates in the binding of photoreceptor rod outer segments during phagocytosis by cultured human retinal pigment epithelium Investigative Ophthalmology and Visual Science. 39: 1703-1712. PMID 9699560  0.84
1998 Chen CH, Clegg DO, Hansma HG. Structures and dynamic motion of laminin-1 as observed by atomic force microscopy Biochemistry. 37: 8262-8267. PMID 9609723 DOI: 10.1021/bi973097j  0.84
1998 Setty S, Kim Y, Fields GB, Clegg DO, Wayner EA, Tsilibary EC. Interactions of type IV collagen and its domains with human mesangial cells Journal of Biological Chemistry. 273: 12244-12249. PMID 9575174 DOI: 10.1074/jbc.273.20.12244  0.84
1997 Anderson DH, Johnson LV, Clegg DO. Exposure of ROS to serum facilitates ros phagocytosis by cultured human RPE Investigative Ophthalmology and Visual Science. 38: S329.  0.84
1996 Cann GM, Bradshaw AD, Gervin DB, Hunter AW, Clegg DO. Widespread expression of beta1 integrins in the developing chick retina: evidence for a role in migration of retinal ganglion cells. Developmental Biology. 180: 82-96. PMID 8948576 DOI: 10.1006/dbio.1996.0286  0.84
1996 Gervin DB, Cann GM, Clegg DO. Temporal and spatial regulation of integrin vitronectin receptor mRNAs in the embryonic chick retina Investigative Ophthalmology and Visual Science. 37: 1084-1096. PMID 8631624  0.84
1996 Lin H, Clegg DO. Arg-Gly-Asp containing peptide inhibits ROS phagocytosis by cultured human RPE Investigative Ophthalmology and Visual Science. 37: S378.  0.84
1996 Clegg DO, Cann GM, Bradshaw AD, Gervin DB, Hunter AW. Role of β1 integrins in retinal development Investigative Ophthalmology and Visual Science. 37: S693.  0.84
1995 Setty S, Anderson SS, Wayner EA, Kim Y, Clegg DO, Tsilibary EC. Glucose-induced alteration of integrin expression and function in cultured human mesangial cells. Cell Adhesion and Communication. 3: 187-200. PMID 8846021 DOI: 10.3109/15419069509081286  0.84
1995 Bradshaw AD, McNagny KM, Gervin DB, Cann GM, Graf T, Clegg DO. Integrin alpha 2 beta 1 mediates interactions between developing embryonic retinal cells and collagen. Development (Cambridge, England). 121: 3593-602. PMID 8582273  0.84
1995 Raichman M, Panzeri MC, Clementi E, Papazafiri P, Eckley M, Clegg DO, Villa A, Meldolesi J. Differential localization and functional role of calsequestrin in growing and differentiated myoblasts. The Journal of Cell Biology. 128: 341-54. PMID 7844148 DOI: 10.1083/jcb.128.3.341  0.84
1994 Choi ESH, Rettig WJ, Wayner EA, Srour ML, Clegg DO. Functional identification of integrin laminin receptors that mediate process outgrowth by human SY5Y neuroblastoma cells Journal of Neuroscience Research. 37: 475-488. PMID 8021971  0.84
1993 Clegg DO. Characterization of a β-nerve growth factor expression vector for mammalian cells Gene. 130: 291-296. PMID 8395451 DOI: 10.1016/0378-1119(93)90434-5  0.84
1993 Volpe P, Gorza L, Brini M, Sacchetto R, Ausoni S, Clegg DO. Expression of the calsequestrin gene in chicken cerebellum Purkinje neurons Biochemical Journal. 294: 487-490. PMID 8373363  0.84
1991 Villa A, Podini P, Clegg DO, Pozzan T, Meldolesi J. Intracellular Ca2+ stores in chicken Purkinje neurons: differential distribution of the low affinity-high capacity Ca2+ binding protein, calsequestrin, of Ca2+ ATPase and of the ER lumenal protein, Bip. The Journal of Cell Biology. 113: 779-91. PMID 1827445  0.84
1991 Choi ESH, Sullivan PD, Clegg DO. Evidence against a laminin receptor role for calsequestrin Biochemical and Biophysical Research Communications. 174: 1208-1216. PMID 1825466 DOI: 10.1016/0006-291X(91)91550-V  0.84
1990 Choi ESH, Clegg DO. Identification and developmental expression of a chicken calsequestrin homolog Developmental Biology. 142: 169-177. PMID 2227093 DOI: 10.1016/0012-1606(90)90160-K  0.84
1990 Muller SR, Sullivan PD, Clegg DO, Feinstein SC. Efficient transfection and expression of heterologous genes in PC12 cells Dna and Cell Biology. 9: 221-229. PMID 2187480  0.84
1989 Clegg DO, Large TH, Bodary SC, Reichardt LF. Regulation of nerve growth factor mRNA levels in developing rat heart ventricle is not altered by sympathectomy. Developmental Biology. 134: 30-7. PMID 2471662 DOI: 10.1016/0012-1606(89)90075-4  0.84
1988 Clegg DO, Helder JC, Hann BC, Hall DE, Reichardt LF. Amino acid sequence and distribution of mRNA encoding a major skeletal muscle laminin binding protein: an extracellular matrix-associated protein with an unusual COOH-terminal polyaspartate domain. The Journal of Cell Biology. 107: 699-705. PMID 3417769  0.84
1986 Large TH, Bodary SC, Clegg DO, Weskamp G, Otten U, Reichardt LF. Nerve growth factor gene expression in the developing rat brain. Science (New York, N.Y.). 234: 352-5. PMID 3764415  0.84
1985 Clegg DO, Koshland DE. Identification of a bacterial sensing protein and effects of its elevated expression Journal of Bacteriology. 162: 398-405. PMID 2984180  0.84
1984 Clegg DO, Koshland DE. The role of a signaling protein in bacterial sensing: Behavioral effects of increased gene expression Proceedings of the National Academy of Sciences of the United States of America. 81: 5056-5060. PMID 6089173  0.84
1982 Wang EA, Mowry KL, Clegg DO, Koshland DE. Tandem duplication and multiple functions of a receptor gene in bacterial chemotaxis. The Journal of Biological Chemistry. 257: 4673-6. PMID 6279644  0.84
1981 Wang JYJ, Clegg DO, Koshland DE. Molecular cloning and amplification of the adenylate cyclase gene Proceedings of the National Academy of Sciences of the United States of America. 78: 4684-4688. PMID 6272270  0.84
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