Dennis Clegg - Publications

Affiliations: 
University of California, Santa Barbara, Santa Barbara, CA, United States 

62/200 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Pollalis D, Georgescu C, Wren JD, Tombulyan G, Leung JM, Lo PA, Bloemhof CM, Lee RH, Bae E, Bailey JK, Pennington BO, Khan AI, Kelly KR, Yeh AK, Sundaram KS, ... ... Clegg DO, et al. Rescuing Photoreceptors in RPE Dysfunction-Driven Retinal Degeneration: The Role of Small Extracellular Vesicles Secreted from Retinal Pigment Epithelium. Biorxiv : the Preprint Server For Biology. PMID 38645051 DOI: 10.1101/2024.04.09.588773  0.418
2024 Leung J, Pollalis D, Nair GKG, Bailey JK, Pennington BO, Khan AI, Kelly KR, Yeh AK, Sundaram KS, Clegg DO, Peng CC, Xu L, Lee SY. Isolation and Characterization of Extracellular Vesicles Through Orthogonal Approaches for the Development of Intraocular EV Therapy. Investigative Ophthalmology & Visual Science. 65: 6. PMID 38466285 DOI: 10.1167/iovs.65.3.6  0.759
2023 Fortress AM, Miyagishima KJ, Reed AA, Temple S, Clegg DO, Tucker BA, Blenkinsop TA, Harb G, Greenwell TN, Ludwig TE, Bharti K. Stem cell sources and characterization in the development of cell-based products for treating retinal disease: An NEI Town Hall report. Stem Cell Research & Therapy. 14: 53. PMID 36978104 DOI: 10.1186/s13287-023-03282-y  0.358
2022 Zhang T, Huang X, Liu S, Bai X, Zhu X, Clegg DO, Jiang M, Sun X. Determining the optimal stage for cryopreservation of human embryonic stem cell-derived retinal pigment epithelial cells. Stem Cell Research & Therapy. 13: 454. PMID 36064625 DOI: 10.1186/s13287-022-03141-2  0.426
2022 Faynus MA, Bailey JK, Pennington BO, Katsura M, Proctor DA, Yeh AK, Menon S, Choi DG, Lebkowski JS, Johnson LV, Clegg DO. Microcarrier-Based Culture of Human Pluripotent Stem-Cell-Derived Retinal Pigmented Epithelium. Bioengineering (Basel, Switzerland). 9. PMID 35877348 DOI: 10.3390/bioengineering9070297  0.799
2021 Pennington BO, Bailey JK, Faynus MA, Hinman C, Hee MN, Ritts R, Nadar V, Zhu D, Mitra D, Martinez-Camarillo JC, Lin TC, Thomas BB, Hinton DR, Humayun MS, Lebkowski J, ... ... Clegg DO, et al. Xeno-free cryopreservation of adherent retinal pigmented epithelium yields viable and functional cells in vitro and in vivo. Scientific Reports. 11: 6286. PMID 33737600 DOI: 10.1038/s41598-021-85631-6  0.379
2019 Kashani AH, Martynova A, Koss M, Brant R, Zhu DH, Lebkowski J, Hinton D, Clegg D, Humayun MS. Subretinal Implantation of a Human Embryonic Stem Cell-Derived Retinal Pigment Epithelium Monolayer in a Porcine Model. Advances in Experimental Medicine and Biology. 1185: 569-574. PMID 31884672 DOI: 10.1007/978-3-030-27378-1_93  0.363
2019 Kashani AH, Uang J, Mert M, Rahhal F, Chan C, Avery RL, Dugel P, Chen S, Lebkowski J, Clegg DO, Hinton DR, Humayun MS. Surgical Method for Implantation of a Biosynthetic Retinal Pigment Epithelium Monolayer for Geographic Atrophy: Experience from a Phase 1/2a Study. Ophthalmology. Retina. PMID 31786135 DOI: 10.1016/J.Oret.2019.09.017  0.315
2018 Foltz LP, Howden SE, Thomson JA, Clegg DO. Functional Assessment of Patient-Derived Retinal Pigment Epithelial Cells Edited by CRISPR/Cas9. International Journal of Molecular Sciences. 19. PMID 30572641 DOI: 10.3390/Ijms19124127  0.397
2018 Foltz LP, Clegg DO. Patient-derived induced pluripotent stem cells for modelling genetic retinal dystrophies. Progress in Retinal and Eye Research. PMID 30217765 DOI: 10.1016/j.preteyeres.2018.09.002  0.396
2018 Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Dang W, Lin CM, Mitra D, Zhu D, Thomas BB, Hikita ST, Pennington BO, Johnson LV, Clegg DO, Hinton DR, et al. A bioengineered retinal pigment epithelial monolayer for advanced, dry age-related macular degeneration. Science Translational Medicine. 10. PMID 29618560 DOI: 10.1126/Scitranslmed.Aao4097  0.758
2017 Foltz LP, Clegg DO. Rapid, Directed Differentiation of Retinal Pigment Epithelial Cells from Human Embryonic or Induced Pluripotent Stem Cells. Journal of Visualized Experiments : Jove. PMID 29155780 DOI: 10.3791/56274  0.378
2017 Lin TC, Seiler MJ, Zhu D, Falabella P, Hinton DR, Clegg DO, Humayun MS, Thomas BB. Assessment of Safety and Functional Efficacy of Stem Cell-Based Therapeutic Approaches Using Retinal Degenerative Animal Models. Stem Cells International. 2017: 9428176. PMID 28928775 DOI: 10.1155/2017/9428176  0.363
2016 Croze RH, Thi WJ, Clegg DO. ROCK Inhibition Promotes Attachment, Proliferation, and Wound Closure in Human Embryonic Stem Cell-Derived Retinal Pigmented Epithelium. Translational Vision Science & Technology. 5: 7. PMID 27917311 DOI: 10.1167/tvst.5.6.7  0.421
2016 Clevenger TN, Luna G, Boctor D, Fisher SK, Clegg DO. Cell-mediated remodeling of biomimetic encapsulating hydrogels triggered by adipogenic differentiation of adipose stem cells. Journal of Tissue Engineering. 7: 2041731416670482. PMID 27733898 DOI: 10.1177/2041731416670482  0.311
2016 Koss MJ, Falabella P, Stefanini FR, Pfister M, Thomas BB, Kashani AH, Brant R, Zhu D, Clegg DO, Hinton DR, Humayun MS. Subretinal implantation of a monolayer of human embryonic stem cell-derived retinal pigment epithelium: a feasibility and safety study in Yucatán minipigs. Graefe's Archive For Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Fur Klinische Und Experimentelle Ophthalmologie. PMID 27335025 DOI: 10.1007/S00417-016-3386-Y  0.331
2016 Thomas BB, Zhu D, Zhang L, Thomas PB, Hu Y, Nazari H, Stefanini F, Falabella P, Clegg DO, Hinton DR, Humayun MS. Survival and Functionality of hESC-Derived Retinal Pigment Epithelium Cells Cultured as a Monolayer on Polymer Substrates Transplanted in RCS Rats. Investigative Ophthalmology & Visual Science. 57: 2877-2887. PMID 27233037 DOI: 10.1167/Iovs.16-19238  0.31
2016 Leach LL, Croze RH, Hu Q, Nadar VP, Clevenger TN, Pennington BO, Gamm DM, Clegg DO. Induced Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium: A Comparative Study Between Cell Lines and Differentiation Methods. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. PMID 27182743 DOI: 10.1089/jop.2016.0022  0.384
2016 Pennington BO, Clegg DO. Pluripotent Stem Cell-Based Therapies in Combination with Substrate for the Treatment of Age-Related Macular Degeneration. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. PMID 26889704 DOI: 10.1089/jop.2015.0153  0.384
2016 Lopez P, Aguilar T, Wu R, Krishnan A, Kong D, Patel J, Javier H, Dang W, Wong D, Zhu D, Dodd J, Shad Y, Humayun M, Hinton D, Clegg D, et al. 445. cGMP Compliant Production for Human Embryonic Stem Cell Derived Retinal Pigment Epithelial Cells on a Synthetic Substrate for the Treatment of Non-Neovascular Age-Related Macular Degeneration for Phase I Clinical Study Molecular Therapy. 24: S176. DOI: 10.1016/S1525-0016(16)33254-3  0.367
2015 Zhao T, Zhang ZN, Westenskow PD, Todorova D, Hu Z, Lin T, Rong Z, Kim J, He J, Wang M, Clegg DO, Yang YG, Zhang K, Friedlander M, Xu Y. Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells. Cell Stem Cell. 17: 353-9. PMID 26299572 DOI: 10.1016/J.Stem.2015.07.021  0.362
2015 Nazari H, Zhang L, Zhu D, Chader GJ, Falabella P, Stefanini F, Rawland T, Clegg DO, Kashani AH, Hinton DR, Humayun MS. Stem cell based therapies for age-related macular degeneration: the promises and the challenges. Progress in Retinal and Eye Research. PMID 26113213 DOI: 10.1016/J.Preteyeres.2015.06.004  0.392
2015 Forest DL, Johnson LV, Clegg DO. Cellular models and therapies for age-related macular degeneration. Disease Models & Mechanisms. 8: 421-7. PMID 26035859 DOI: 10.1242/Dmm.017236  0.364
2015 Leach LL, Clegg DO. Concise Review: Making Stem Cells Retinal: Methods for Deriving Retinal Pigment Epithelium and Implications for Patients With Ocular Disease. Stem Cells (Dayton, Ohio). 33: 2363-73. PMID 25809736 DOI: 10.1002/stem.2010  0.407
2015 Leach LL, Buchholz DE, Nadar VP, Lowenstein SE, Clegg DO. Canonical/β-catenin Wnt pathway activation improves retinal pigmented epithelium derivation from human embryonic stem cells. Investigative Ophthalmology & Visual Science. 56: 1002-13. PMID 25604686 DOI: 10.1167/iovs.14-15835  0.318
2015 Pennington BO, Clegg DO, Melkoumian ZK, Hikita ST. Defined culture of human embryonic stem cells and xeno-free derivation of retinal pigmented epithelial cells on a novel, synthetic substrate. Stem Cells Translational Medicine. 4: 165-77. PMID 25593208 DOI: 10.5966/Sctm.2014-0179  0.785
2014 Hu Q, Chen R, Teesalu T, Ruoslahti E, Clegg DO. Reprogramming human retinal pigmented epithelial cells to neurons using recombinant proteins. Stem Cells Translational Medicine. 3: 1526-34. PMID 25298373 DOI: 10.5966/Sctm.2014-0038  0.378
2014 Croze RH, Buchholz DE, Radeke MJ, Thi WJ, Hu Q, Coffey PJ, Clegg DO. ROCK Inhibition Extends Passage of Pluripotent Stem Cell-Derived Retinal Pigmented Epithelium. Stem Cells Translational Medicine. 3: 1066-78. PMID 25069775 DOI: 10.5966/sctm.2014-0079  0.393
2014 Croze RH, Clegg DO. Differentiation of pluripotent stem cells into retinal pigmented epithelium. Developments in Ophthalmology. 53: 81-96. PMID 24732763 DOI: 10.1159/000357361  0.365
2014 Clegg D. Stem cell strategies for retinal disease Journal of Vision. 14: 3-3. DOI: 10.1167/14.15.3  0.458
2013 Buchholz DE, Pennington BO, Croze RH, Hinman CR, Coffey PJ, Clegg DO. Rapid and efficient directed differentiation of human pluripotent stem cells into retinal pigmented epithelium. Stem Cells Translational Medicine. 2: 384-93. PMID 23599499 DOI: 10.5966/sctm.2012-0163  0.39
2013 Rowland TJ, Blaschke AJ, Buchholz DE, Hikita ST, Johnson LV, Clegg DO. Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins. Journal of Tissue Engineering and Regenerative Medicine. 7: 642-53. PMID 22514096 DOI: 10.1002/Term.1458  0.82
2012 Hu Y, Liu L, Lu B, Zhu D, Ribeiro R, Diniz B, Thomas PB, Ahuja AK, Hinton DR, Tai YC, Hikita ST, Johnson LV, Clegg DO, Thomas BB, Humayun MS. A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer. Ophthalmic Research. 48: 186-91. PMID 22868580 DOI: 10.1159/000338749  0.772
2012 Rowland TJ, Buchholz DE, Clegg DO. Pluripotent human stem cells for the treatment of retinal disease. Journal of Cellular Physiology. 227: 457-66. PMID 21520078 DOI: 10.1002/Jcp.22814  0.707
2010 Gupta N, Lin BF, Campos LM, Dimitriou MD, Hikita ST, Treat ND, Tirrell MV, Clegg DO, Kramer EJ, Hawker CJ. A versatile approach to high-throughput microarrays using thiol-ene chemistry. Nature Chemistry. 2: 138-45. PMID 21124405 DOI: 10.1038/Nchem.1328  0.721
2010 Hu Q, Friedrich AM, Johnson LV, Clegg DO. Memory in induced pluripotent stem cells: reprogrammed human retinal-pigmented epithelial cells show tendency for spontaneous redifferentiation. Stem Cells (Dayton, Ohio). 28: 1981-91. PMID 20882530 DOI: 10.1002/Stem.531  0.374
2010 Kolhar P, Kotamraju VR, Hikita ST, Clegg DO, Ruoslahti E. Synthetic surfaces for human embryonic stem cell culture. Journal of Biotechnology. 146: 143-6. PMID 20132848 DOI: 10.1016/J.Jbiotec.2010.01.016  0.764
2010 Rowland TJ, Miller LM, Blaschke AJ, Doss EL, Bonham AJ, Hikita ST, Johnson LV, Clegg DO. Roles of integrins in human induced pluripotent stem cell growth on Matrigel and vitronectin. Stem Cells and Development. 19: 1231-40. PMID 19811096 DOI: 10.1089/Scd.2009.0328  0.823
2010 Buchholz DE, Hikita ST, Radeke MJ, Blashke KE, Johnson LV, Clegg DO. Stem cell derived retinal pigment Epithelium for the treatment of age-related Macular degeneration Journal of Vision. 8: 47-47. DOI: 10.1167/8.17.47  0.78
2009 Carr AJ, Vugler AA, Hikita ST, Lawrence JM, Gias C, Chen LL, Buchholz DE, Ahmado A, Semo M, Smart MJ, Hasan S, da Cruz L, Johnson LV, Clegg DO, Coffey PJ. Protective effects of human iPS-derived retinal pigment epithelium cell transplantation in the retinal dystrophic rat. Plos One. 4: e8152. PMID 19997644 DOI: 10.1371/Journal.Pone.0008152  0.812
2009 Buchholz DE, Hikita ST, Rowland TJ, Friedrich AM, Hinman CR, Johnson LV, Clegg DO. Derivation of functional retinal pigmented epithelium from induced pluripotent stem cells. Stem Cells (Dayton, Ohio). 27: 2427-34. PMID 19658190 DOI: 10.1002/Stem.189  0.827
2008 Hikita ST, Kosik KS, Clegg DO, Bamdad C. MUC1* mediates the growth of human pluripotent stem cells. Plos One. 3: e3312. PMID 18833326 DOI: 10.1371/Journal.Pone.0003312  0.763
2007 Dunkle ET, Zaucke F, Clegg DO. Thrombospondin-4 and matrix three-dimensionality in axon outgrowth and adhesion in the developing retina. Experimental Eye Research. 84: 707-17. PMID 17320079 DOI: 10.1016/J.Exer.2006.12.014  0.753
2006 Hikita ST, Vistica BP, Jones HR, Keswani JR, Watson MM, Ericson VR, Ayoub GS, Gery I, Clegg DO. Osteopontin is proinflammatory in experimental autoimmune uveitis. Investigative Ophthalmology & Visual Science. 47: 4435-43. PMID 17003437 DOI: 10.1167/Iovs.06-0064  0.749
2005 Wingerd KL, Wayne WC, Jackson DY, Clegg DO. Involvement of alpha4 integrins in maintenance of cardiac sympathetic axons. Autonomic Neuroscience : Basic & Clinical. 122: 58-68. PMID 16181811 DOI: 10.1016/J.Autneu.2005.08.006  0.792
2005 Putzke AP, Hikita ST, Clegg DO, Rothman JH. Essential kinase-independent role of a Fer-like non-receptor tyrosine kinase in Caenorhabditis elegans morphogenesis. Development (Cambridge, England). 132: 3185-95. PMID 15958510 DOI: 10.1242/Dev.01900  0.762
2004 Leu ST, Jacques SA, Wingerd KL, Hikita ST, Tolhurst EC, Pring JL, Wiswell D, Kinney L, Goodman NL, Jackson DY, Clegg DO. Integrin alpha4beta1 function is required for cell survival in developing retina. Developmental Biology. 276: 416-30. PMID 15581875 DOI: 10.1016/J.Ydbio.2004.09.003  0.815
2004 Wingerd KL, Goodman NL, Leu ST, Clegg DO. Expression and function of integrin alpha4beta1 and vascular cell adhesion molecule-1 (VCAM-1) during sympathetic innervation of the heart. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 231: 359-69. PMID 15366013 DOI: 10.1002/Dvdy.20120  0.804
2003 Hikita ST, Cann GM, Wingerd KL, Mullick LH, Wayne WC, Webb SW, Clegg DO. Integrin alpha4beta1 (VLA-4) expression and activity in retinal and peripheral neurons. Molecular and Cellular Neurosciences. 23: 427-39. PMID 12837626 DOI: 10.1016/S1044-7431(03)00065-4  0.796
2003 Clegg DO, Wingerd KL, Hikita ST, Tolhurst EC. Integrins in the development, function and dysfunction of the nervous system. Frontiers in Bioscience : a Journal and Virtual Library. 8: d723-50. PMID 12700040 DOI: 10.2741/1020  0.798
2002 Wingerd KL, Goodman NL, Tresser JW, Smail MM, Leu ST, Rohan SJ, Pring JL, Jackson DY, Clegg DO. Alpha 4 integrins and vascular cell adhesion molecule-1 play a role in sympathetic innervation of the heart. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 10772-80. PMID 12486170  0.791
2001 Leonoudakis D, Mailliard W, Wingerd K, Clegg D, Vandenberg C. Inward rectifier potassium channel Kir2.2 is associated with synapse-associated protein SAP97. Journal of Cell Science. 114: 987-98. PMID 11181181  0.759
2000 Clegg DO, Mullick LH, Wingerd KL, Lin H, Atienza JW, Bradshaw AD, Gervin DB, Cann GM. Adhesive events in retinal development and function: the role of integrin receptors. Results and Problems in Cell Differentiation. 31: 141-56. PMID 10929405 DOI: 10.1007/978-3-540-46826-4_8  0.832
1998 Kil SH, Krull CE, Cann G, Clegg D, Bronner-Fraser M. The alpha4 subunit of integrin is important for neural crest cell migration. Developmental Biology. 202: 29-42. PMID 9758701 DOI: 10.1006/Dbio.1998.8985  0.421
1996 Cann GM, Bradshaw AD, Gervin DB, Hunter AW, Clegg DO. Widespread expression of beta1 integrins in the developing chick retina: evidence for a role in migration of retinal ganglion cells. Developmental Biology. 180: 82-96. PMID 8948576 DOI: 10.1006/Dbio.1996.0286  0.692
1996 Smith BE, Bradshaw AD, Choi ES, Rouselle P, Wayner EA, Clegg DO. Human SY5Y neuroblastoma cell interactions with laminin isoforms: neurite outgrowth on laminin-5 is mediated by integrin alpha 3 beta 1. Cell Adhesion and Communication. 3: 451-62. PMID 8807189 DOI: 10.3109/15419069609081022  0.649
1995 Setty S, Anderson SS, Wayner EA, Kim Y, Clegg DO, Tsilibary EC. Glucose-induced alteration of integrin expression and function in cultured human mesangial cells. Cell Adhesion and Communication. 3: 187-200. PMID 8846021 DOI: 10.3109/15419069509081286  0.328
1995 Bradshaw AD, McNagny KM, Gervin DB, Cann GM, Graf T, Clegg DO. Integrin alpha 2 beta 1 mediates interactions between developing embryonic retinal cells and collagen. Development (Cambridge, England). 121: 3593-602. PMID 8582273  0.456
1985 Clegg DO, Koshland DE. Identification of a bacterial sensing protein and effects of its elevated expression Journal of Bacteriology. 162: 398-405. PMID 2984180 DOI: 10.1128/Jb.162.1.398-405.1985  0.36
1984 Clegg DO, Koshland DE. The role of a signaling protein in bacterial sensing: Behavioral effects of increased gene expression Proceedings of the National Academy of Sciences of the United States of America. 81: 5056-5060. PMID 6089173 DOI: 10.1073/Pnas.81.16.5056  0.364
1982 Wang EA, Mowry KL, Clegg DO, Koshland DE. Tandem duplication and multiple functions of a receptor gene in bacterial chemotaxis. The Journal of Biological Chemistry. 257: 4673-6. PMID 6279644  0.347
1981 Wang JYJ, Clegg DO, Koshland DE. Molecular cloning and amplification of the adenylate cyclase gene Proceedings of the National Academy of Sciences of the United States of America. 78: 4684-4688. PMID 6272270 DOI: 10.1073/Pnas.78.8.4684  0.341
Low-probability matches (unlikely to be authored by this person)
2016 Brant Fernandes RA, Koss MJ, Falabella P, Stefanini FR, Maia M, Diniz B, Ribeiro R, Hu Y, Hinton D, Clegg DO, Chader G, Humayun MS. An Innovative Surgical Technique for Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Pigmented Epithelium in Yucatan Mini Pigs: Preliminary Results. Ophthalmic Surgery, Lasers & Imaging Retina. 47: 342-351. PMID 27065374 DOI: 10.3928/23258160-20160324-07  0.3
2014 Zhao T, Zhang Zn, Westenskow PD, Todorova D, Hu Z, Lin T, Rong Z, Kim J, He J, Wang M, Clegg DO, Yang Yg, Zhang K, Friedlander M, Xu Y. Humanized Mice Reveal Differential Immunogenicity of Cells Derived from Autologous Induced Pluripotent Stem Cells Cell Stem Cell. DOI: 10.1016/j.stem.2015.07.021  0.297
2016 Clevenger TN, Hinman CR, Ashley Rubin RK, Smither K, Burke DJ, Hawker CJ, Messina D, van Epps D, Clegg DO. Vitronectin-based, biomimetic encapsulating hydrogel scaffolds support adipogenesis of adipose stem cells. Tissue Engineering. Part A. PMID 26956095 DOI: 10.1089/Ten.Tea.2015.0550  0.29
2016 Clevenger TN, Luna G, Fisher SK, Clegg DO. Strategies for bioengineered scaffolds that support adipose stem cells in regenerative therapies. Regenerative Medicine. PMID 27484203 DOI: 10.2217/rme-2016-0064  0.286
2002 Mey A, Gandrillon O, McNagny KM, Clegg DO, Samarut J. The v-erbA oncogene blocks expression of alpha2/beta1 integrin a normal inhibitor of erythroid progenitor proliferation. Oncogene. 21: 2864-72. PMID 11973646 DOI: 10.1038/sj.onc.1205411  0.286
1991 Choi ESH, Sullivan PD, Clegg DO. Evidence against a laminin receptor role for calsequestrin Biochemical and Biophysical Research Communications. 174: 1208-1216. PMID 1825466 DOI: 10.1016/0006-291X(91)91550-V  0.282
2016 Huang X, Hu Q, Lai Y, Morales DP, Clegg DO, Reich NO. Light-Patterned RNA Interference of 3D-Cultured Human Embryonic Stem Cells. Advanced Materials (Deerfield Beach, Fla.). PMID 27787919 DOI: 10.1002/Adma.201603318  0.281
2023 Shlosberg Y, Faynus MA, Huang A, Carlini AS, Clegg DO, Kaner RB. Mammalian Fuel Cells Produce Electric Current. Acs Applied Materials & Interfaces. PMID 37450569 DOI: 10.1021/acsami.3c06019  0.28
2022 Kashani AH, Lebkowski JS, Hinton DR, Zhu D, Faynus MA, Chen S, Rahhal FM, Avery RL, Salehi-Had H, Chan C, Palejwala N, Ingram A, Dang W, Lin CM, Mitra D, ... ... Clegg DO, et al. Survival of an HLA-mismatched, bioengineered RPE implant in dry age-related macular degeneration. Stem Cell Reports. PMID 35120620 DOI: 10.1016/j.stemcr.2022.01.001  0.277
2021 Kashani AH, Lebkowski JS, Rahhal FM, Avery RL, Salehi-Had H, Chen S, Chan C, Palejwala N, Ingram A, Dang W, Lin CM, Mitra D, Pennington BO, Hinman C, Faynus MA, ... ... Clegg DO, et al. One-Year Follow-Up in a Phase 1/2a Clinical Trial of an Allogeneic RPE Cell Bioengineered Implant for Advanced Dry Age-Related Macular Degeneration. Translational Vision Science & Technology. 10: 13. PMID 34613357 DOI: 10.1167/tvst.10.10.13  0.266
2023 Conrad JV, Meyer S, Ramesh PS, Neira JA, Rusteika M, Mamott D, Duffin B, Bautista M, Zhang J, Hiles E, Higgins EM, Steill J, Freeman J, Ni Z, Liu S, ... ... Clegg DO, et al. Efficient derivation of transgene-free porcine induced pluripotent stem cells enables in vitro modeling of species-specific developmental timing. Stem Cell Reports. PMID 37949072 DOI: 10.1016/j.stemcr.2023.10.009  0.26
2022 Chirikian O, Feinstein S, Faynus MA, Kim AA, Lane K, Torres G, Pham J, Singh Z, Nguyen A, Thomas D, Clegg DO, Wu JC, Pruitt BL. The effects of xeno-free cryopreservation on the contractile properties of human iPSC derived cardiomyocytes. Journal of Molecular and Cellular Cardiology. PMID 35461823 DOI: 10.1016/j.yjmcc.2022.04.010  0.258
2023 Humayun MS, Clegg DO, Dayan MS, Kashani AH, Rahhal FM, Avery RL, Salehi-Had H, Chen S, Chan C, Palejwala N, Ingram A, Mitra D, Pennington BO, Hinman C, Faynus MA, et al. Long-term Follow-Up of Subjects in a Phase 1/2a Clinical Trial of Stem Cell-Derived Bioengineered Retinal Pigment Epithelium Implant for Geographic Atrophy. Ophthalmology. PMID 38160882 DOI: 10.1016/j.ophtha.2023.12.028  0.256
2015 Huang X, Hu Q, Braun GB, Pallaoro A, Morales DP, Zasadzinski J, Clegg DO, Reich NO. Light-activated RNA interference in human embryonic stem cells. Biomaterials. 63: 70-9. PMID 26086448 DOI: 10.1016/J.Biomaterials.2015.06.006  0.255
2002 Leu ST, Batni S, Radeke MJ, Johnson LV, Anderson DH, Clegg DO. Drusen are Cold Spots for Proteolysis: Expression of Matrix Metalloproteinases and Their Tissue Inhibitor Proteins in Age-related Macular Degeneration. Experimental Eye Research. 74: 141-54. PMID 11878827 DOI: 10.1006/Exer.2001.1112  0.254
1998 Lin H, Clegg DO. Integrin αvβ5 participates in the binding of photoreceptor rod outer segments during phagocytosis by cultured human retinal pigment epithelium Investigative Ophthalmology and Visual Science. 39: 1703-1712. PMID 9699560  0.245
1990 Muller SR, Sullivan PD, Clegg DO, Feinstein SC. Efficient transfection and expression of heterologous genes in PC12 cells Dna and Cell Biology. 9: 221-229. PMID 2187480  0.244
1986 Large TH, Bodary SC, Clegg DO, Weskamp G, Otten U, Reichardt LF. Nerve growth factor gene expression in the developing rat brain. Science (New York, N.Y.). 234: 352-5. PMID 3764415 DOI: 10.1126/Science.3764415  0.243
2017 Gornalusse GG, Hirata RK, Funk SE, Riolobos L, Lopes VS, Manske G, Prunkard D, Colunga AG, Hanafi LA, Clegg DO, Turtle C, Russell DW. HLA-E-expressing pluripotent stem cells escape allogeneic responses and lysis by NK cells. Nature Biotechnology. PMID 28504668 DOI: 10.1038/Nbt.3860  0.235
2010 Neveu P, Kye MJ, Qi S, Buchholz DE, Clegg DO, Sahin M, Park IH, Kim KS, Daley GQ, Kornblum HI, Shraiman BI, Kosik KS. MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states. Cell Stem Cell. 7: 671-81. PMID 21112562 DOI: 10.1016/J.Stem.2010.11.012  0.232
1996 Clegg DO, Cann GM, Bradshaw AD, Gervin DB, Hunter AW. Role of β1 integrins in retinal development Investigative Ophthalmology and Visual Science. 37: S693.  0.223
2001 Culley B, Murphy J, Babaie J, Nguyen D, Pagel A, Rousselle P, Clegg DO. Laminin-5 promotes neurite outgrowth from central and peripheral chick embryonic neurons Neuroscience Letters. 301: 83-86. PMID 11248428 DOI: 10.1016/S0304-3940(01)01615-9  0.218
1994 Choi ESH, Rettig WJ, Wayner EA, Srour ML, Clegg DO. Functional identification of integrin laminin receptors that mediate process outgrowth by human SY5Y neuroblastoma cells Journal of Neuroscience Research. 37: 475-488. PMID 8021971  0.216
1996 Lin H, Clegg DO. Arg-Gly-Asp containing peptide inhibits ROS phagocytosis by cultured human RPE Investigative Ophthalmology and Visual Science. 37: S378.  0.205
2014 Lapid K, Lim A, Clegg DJ, Zeve D, Graff JM. Oestrogen signalling in white adipose progenitor cells inhibits differentiation into brown adipose and smooth muscle cells. Nature Communications. 5: 5196. PMID 25330806 DOI: 10.1038/Ncomms6196  0.18
1998 Setty S, Kim Y, Fields GB, Clegg DO, Wayner EA, Tsilibary EC. Interactions of type IV collagen and its domains with human mesangial cells Journal of Biological Chemistry. 273: 12244-12249. PMID 9575174 DOI: 10.1074/jbc.273.20.12244  0.175
2000 Clegg DO. Novel roles for integrins in the nervous system Molecular Cell Biology Research Communications. 3: 1-7. PMID 10683310 DOI: 10.1006/mcbr.1999.0175  0.172
1996 Gervin DB, Cann GM, Clegg DO. Temporal and spatial regulation of integrin vitronectin receptor mRNAs in the embryonic chick retina Investigative Ophthalmology and Visual Science. 37: 1084-1096. PMID 8631624  0.172
2016 Clegg DO. Regenerating Perfection. Journal of Ocular Pharmacology and Therapeutics : the Official Journal of the Association For Ocular Pharmacology and Therapeutics. PMID 27214692 DOI: 10.1089/jop.2016.29013.doclegg  0.17
2017 Siegel KR, Clevenger TN, Clegg DO, Proctor DA, Proctor CS. Adipose Stem Cells Incorporated in Fibrin Clot Modulate Expression of Growth Factors. Arthroscopy : the Journal of Arthroscopic & Related Surgery : Official Publication of the Arthroscopy Association of North America and the International Arthroscopy Association. PMID 29100775 DOI: 10.1016/j.arthro.2017.08.250  0.167
1993 Volpe P, Gorza L, Brini M, Sacchetto R, Ausoni S, Clegg DO. Expression of the calsequestrin gene in chicken cerebellum Purkinje neurons Biochemical Journal. 294: 487-490. PMID 8373363  0.161
2010 Irani BG, Donato J, Olson DP, Lowell BB, Sacktor TC, Reyland ME, Tolson KP, Zinn AR, Ueta Y, Sakata I, Zigman JM, Elias CF, Clegg DJ. Distribution and neurochemical characterization of protein kinase C-theta and -delta in the rodent hypothalamus. Neuroscience. 170: 1065-79. PMID 20691763 DOI: 10.1016/J.Neuroscience.2010.07.064  0.159
2019 Toh H, Smolentsev A, Bozadjian RV, Keeley PW, Lockwood MD, Sadjadi R, Clegg DO, Blodi BA, Coffey PJ, Reese BE, Thomson JA. Vascular changes in diabetic retinopathy-a longitudinal study in the Nile rat. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 31101854 DOI: 10.1038/S41374-019-0264-3  0.157
2015 Waters EM, Thompson LI, Patel P, Gonzales AD, Ye HZ, Filardo EJ, Clegg DJ, Gorecka J, Akama KT, McEwen BS, Milner TA. G-protein-coupled estrogen receptor 1 is anatomically positioned to modulate synaptic plasticity in the mouse hippocampus. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 2384-97. PMID 25673833 DOI: 10.1523/Jneurosci.1298-14.2015  0.155
1993 Clegg DO. Characterization of a β-nerve growth factor expression vector for mammalian cells Gene. 130: 291-296. PMID 8395451 DOI: 10.1016/0378-1119(93)90434-5  0.152
1999 Lin H, Clegg DO, Lal R. Imaging real-time proteolysis of single collagen I molecules with an atomic force microscope Biochemistry. 38: 9956-9963. PMID 10433702 DOI: 10.1021/bi990800q  0.145
2013 Frazão R, Cravo RM, Donato J, Ratra DV, Clegg DJ, Elmquist JK, Zigman JM, Williams KW, Elias CF. Shift in Kiss1 cell activity requires estrogen receptor α. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 2807-20. PMID 23407940 DOI: 10.1523/Jneurosci.1610-12.2013  0.144
1998 Chen CH, Clegg DO, Hansma HG. Structures and dynamic motion of laminin-1 as observed by atomic force microscopy Biochemistry. 37: 8262-8267. PMID 9609723 DOI: 10.1021/bi973097j  0.143
1988 Clegg DO, Helder JC, Hann BC, Hall DE, Reichardt LF. Amino acid sequence and distribution of mRNA encoding a major skeletal muscle laminin binding protein: an extracellular matrix-associated protein with an unusual COOH-terminal polyaspartate domain. The Journal of Cell Biology. 107: 699-705. PMID 3417769 DOI: 10.1083/Jcb.107.2.699  0.143
1990 Choi ESH, Clegg DO. Identification and developmental expression of a chicken calsequestrin homolog Developmental Biology. 142: 169-177. PMID 2227093 DOI: 10.1016/0012-1606(90)90160-K  0.143
1989 Clegg DO, Large TH, Bodary SC, Reichardt LF. Regulation of nerve growth factor mRNA levels in developing rat heart ventricle is not altered by sympathectomy. Developmental Biology. 134: 30-7. PMID 2471662 DOI: 10.1016/0012-1606(89)90075-4  0.126
1995 Raichman M, Panzeri MC, Clementi E, Papazafiri P, Eckley M, Clegg DO, Villa A, Meldolesi J. Differential localization and functional role of calsequestrin in growing and differentiated myoblasts. The Journal of Cell Biology. 128: 341-54. PMID 7844148 DOI: 10.1083/Jcb.128.3.341  0.122
2013 Fuente-Martin E, Garcia-Caceres C, Morselli E, Clegg DJ, Chowen JA, Finan B, Brinton RD, Tschöp MH. Estrogen, astrocytes and the neuroendocrine control of metabolism. Reviews in Endocrine & Metabolic Disorders. 14: 331-8. PMID 24009071 DOI: 10.1007/S11154-013-9263-7  0.122
2023 Toh H, Smolentsev A, Sadjadi R, Clegg D, Yan J, Stewart R, Thomson JA, Jiang P. Transcriptomic clock predicts vascular changes of prodromal diabetic retinopathy. Scientific Reports. 13: 12968. PMID 37563287 DOI: 10.1038/s41598-023-40328-w  0.121
2011 Xu Y, Nedungadi TP, Zhu L, Sobhani N, Irani BG, Davis KE, Zhang X, Zou F, Gent LM, Hahner LD, Khan SA, Elias CF, Elmquist JK, Clegg DJ. Distinct hypothalamic neurons mediate estrogenic effects on energy homeostasis and reproduction. Cell Metabolism. 14: 453-65. PMID 21982706 DOI: 10.1016/J.Cmet.2011.08.009  0.121
2010 Zheng Q, Zhu J, Shanabrough M, Borok E, Benoit SC, Horvath TL, Clegg DJ, Reizes O. Enhanced anorexigenic signaling in lean obesity resistant syndecan-3 null mice. Neuroscience. 171: 1032-40. PMID 20923696 DOI: 10.1016/J.Neuroscience.2010.09.060  0.12
2015 Zhu L, Xu P, Cao X, Yang Y, Hinton AO, Xia Y, Saito K, Yan X, Zou F, Ding H, Wang C, Yan C, Saha P, Khan SA, Zhao J, ... ... Clegg DJ, et al. The ERα-PI3K Cascade in Pro-opiomelanocortin Progenitor Neurons Regulates Feeding and Glucose Balance in Female Mice. Endocrinology. en20151660. PMID 26375425 DOI: 10.1210/En.2015-1660  0.119
1997 Anderson DH, Johnson LV, Clegg DO. Exposure of ROS to serum facilitates ros phagocytosis by cultured human RPE Investigative Ophthalmology and Visual Science. 38: S329.  0.116
2016 Saito K, He Y, Yang Y, Zhu L, Wang C, Xu P, Hinton AO, Yan X, Zhao J, Fukuda M, Tong Q, Clegg DJ, Xu Y. PI3K in the ventromedial hypothalamic nucleus mediates estrogenic actions on energy expenditure in female mice. Scientific Reports. 6: 23459. PMID 26988598 DOI: 10.1038/Srep23459  0.113
2015 Xu P, Cao X, He Y, Zhu L, Yang Y, Saito K, Wang C, Yan X, Hinton AO, Zou F, Ding H, Xia Y, Yan C, Shu G, Wu SP, ... ... Clegg DJ, et al. Estrogen receptor-α in medial amygdala neurons regulates body weight. The Journal of Clinical Investigation. 125: 2861-76. PMID 26098212 DOI: 10.1172/Jci80941  0.112
1991 Villa A, Podini P, Clegg DO, Pozzan T, Meldolesi J. Intracellular Ca2+ stores in chicken Purkinje neurons: differential distribution of the low affinity-high capacity Ca2+ binding protein, calsequestrin, of Ca2+ ATPase and of the ER lumenal protein, Bip. The Journal of Cell Biology. 113: 779-91. PMID 1827445 DOI: 10.1083/Jcb.113.4.779  0.11
2014 Palmer BF, Clegg DJ. Oxygen sensing and metabolic homeostasis. Molecular and Cellular Endocrinology. 397: 51-8. PMID 25132648 DOI: 10.1016/J.Mce.2014.08.001  0.109
2014 Frank A, Brown LM, Clegg DJ. The role of hypothalamic estrogen receptors in metabolic regulation. Frontiers in Neuroendocrinology. 35: 550-7. PMID 24882636 DOI: 10.1016/J.Yfrne.2014.05.002  0.109
2014 Cao X, Xu P, Oyola MG, Xia Y, Yan X, Saito K, Zou F, Wang C, Yang Y, Hinton A, Yan C, Ding H, Zhu L, Yu L, Yang B, ... ... Clegg DJ, et al. Estrogens stimulate serotonin neurons to inhibit binge-like eating in mice. The Journal of Clinical Investigation. 124: 4351-62. PMID 25157819 DOI: 10.1172/Jci74726  0.107
2016 Hinton AO, He Y, Xia Y, Xu P, Yang Y, Saito K, Wang C, Yan X, Shu G, Henderson A, Clegg DJ, Khan SA, Reynolds C, Wu Q, Tong Q, et al. Estrogen Receptor-α in the Medial Amygdala Prevents Stress-Induced Elevations in Blood Pressure in Females. Hypertension. PMID 27091896 DOI: 10.1161/Hypertensionaha.116.07175  0.105
2022 Toh H, Yang C, Formenti G, Raja K, Yan L, Tracey A, Chow W, Howe K, Bergeron LA, Zhang G, Haase B, Mountcastle J, Fedrigo O, Fogg J, Kirilenko B, ... ... Clegg DO, et al. A haplotype-resolved genome assembly of the Nile rat facilitates exploration of the genetic basis of diabetes. Bmc Biology. 20: 245. PMID 36344967 DOI: 10.1186/s12915-022-01427-8  0.104
2015 Hevener AL, Clegg DJ, Mauvais-Jarvis F. Impaired estrogen receptor action in the pathogenesis of the metabolic syndrome. Molecular and Cellular Endocrinology. PMID 26033249 DOI: 10.1016/J.Mce.2015.05.020  0.098
2013 Mauvais-Jarvis F, Clegg DJ, Hevener AL. The role of estrogens in control of energy balance and glucose homeostasis. Endocrine Reviews. 34: 309-38. PMID 23460719 DOI: 10.1210/Er.2012-1055  0.097
2014 Morselli E, Fuente-Martin E, Finan B, Kim M, Frank A, Garcia-Caceres C, Navas CR, Gordillo R, Neinast M, Kalainayakan SP, Li DL, Gao Y, Yi CX, Hahner L, Palmer BF, ... ... Clegg DJ, et al. Hypothalamic PGC-1α protects against high-fat diet exposure by regulating ERα. Cell Reports. 9: 633-45. PMID 25373903 DOI: 10.1016/J.Celrep.2014.09.025  0.096
2002 Hansma HG, Clegg DO, Kokkoli E, Oroudjev E, Tirrell M. Analysis of matrix dynamics by atomic force microscopy. Methods in Cell Biology. 69: 163-93. PMID 12070991 DOI: 10.1016/S0091-679X(02)69012-0  0.096
2011 Ford J, Hajibeigi A, Long M, Hahner L, Gore C, Hsieh JT, Clegg D, Zerwekh J, Öz OK. GPR30 deficiency causes increased bone mass, mineralization, and growth plate proliferative activity in male mice Journal of Bone and Mineral Research. 26: 298-307. PMID 20734455 DOI: 10.1002/Jbmr.209  0.091
2010 Brown LM, Gent L, Davis K, Clegg DJ. Metabolic impact of sex hormones on obesity. Brain Research. 1350: 77-85. PMID 20441773 DOI: 10.1016/J.Brainres.2010.04.056  0.089
2013 Brown LM, Clegg DJ. Estrogen and leptin regulation of endocrinological features of anorexia nervosa. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 38: 237. PMID 23147480 DOI: 10.1038/Npp.2012.176  0.083
2014 Palmer BF, Clegg DJ. Ascent to altitude as a weight loss method: the good and bad of hypoxia inducible factor activation. Obesity (Silver Spring, Md.). 22: 311-7. PMID 23625659 DOI: 10.1002/Oby.20499  0.083
2015 Palmer BF, Clegg DJ. An Emerging Role of Natriuretic Peptides: Igniting the Fat Furnace to Fuel and Warm the Heart. Mayo Clinic Proceedings. PMID 26518101 DOI: 10.1016/j.mayocp.2015.08.006  0.081
2015 Neinast MD, Frank AP, Zechner JF, Li Q, Vishvanath L, Palmer BF, Aguirre V, Gupta RK, Clegg DJ. Activation of natriuretic peptides and the sympathetic nervous system following Roux-en-Y gastric bypass is associated with gonadal adipose tissues browning. Molecular Metabolism. 4: 427-36. PMID 25973390 DOI: 10.1016/J.Molmet.2015.02.006  0.081
2015 Palmer BF, Clegg DJ. The sexual dimorphism of obesity. Molecular and Cellular Endocrinology. 402: 113-9. PMID 25578600 DOI: 10.1016/J.Mce.2014.11.029  0.081
2014 Kim M, Neinast MD, Frank AP, Sun K, Park J, Zehr JA, Vishvanath L, Morselli E, Amelotte M, Palmer BF, Gupta RK, Scherer PE, Clegg DJ. ERα upregulates Phd3 to ameliorate HIF-1 induced fibrosis and inflammation in adipose tissue. Molecular Metabolism. 3: 642-51. PMID 25161887 DOI: 10.1016/J.Molmet.2014.05.007  0.081
2011 Miller KL, Clegg DO. Glucosamine and chondroitin sulfate. Rheumatic Diseases Clinics of North America. 37: 103-18. PMID 21220090 DOI: 10.1016/j.rdc.2010.11.007  0.077
2014 Davis KE, Carstens EJ, Irani BG, Gent LM, Hahner LM, Clegg DJ. Sexually dimorphic role of G protein-coupled estrogen receptor (GPER) in modulating energy homeostasis. Hormones and Behavior. 66: 196-207. PMID 24560890 DOI: 10.1016/J.Yhbeh.2014.02.004  0.076
2014 Picard A, Rouch C, Kassis N, Moullé VS, Croizier S, Denis RG, Castel J, Coant N, Davis K, Clegg DJ, Benoit SC, Prévot V, Bouret S, Luquet S, Le Stunff H, et al. Hippocampal lipoprotein lipase regulates energy balance in rodents. Molecular Metabolism. 3: 167-76. PMID 24634821 DOI: 10.1016/J.Molmet.2013.11.002  0.076
2000 Lin H, Lal R, Clegg DO. Imaging and mapping heparin-binding sites on single fibronectin molecules with atomic force microscopy Biochemistry. 39: 3192-3196. PMID 10727210 DOI: 10.1021/bi991624o  0.071
2011 Davis JF, Choi DL, Clegg DJ, Benoit SC. Signaling through the ghrelin receptor modulates hippocampal function and meal anticipation in mice. Physiology & Behavior. 103: 39-43. PMID 21036184 DOI: 10.1016/J.Physbeh.2010.10.017  0.069
2013 Davis KE, D Neinast M, Sun K, M Skiles W, D Bills J, A Zehr J, Zeve D, D Hahner L, W Cox D, M Gent L, Xu Y, V Wang Z, A Khan S, Clegg DJ. The sexually dimorphic role of adipose and adipocyte estrogen receptors in modulating adipose tissue expansion, inflammation, and fibrosis. Molecular Metabolism. 2: 227-42. PMID 24049737 DOI: 10.1016/J.Molmet.2013.05.006  0.069
2010 Weisman M, Learch TJ, Baraliakos X, Chandran V, Gladman DD, Raychaudhuri SP, Xu H, Collantes-Estévez E, Vázquez-Mellado J, Mease PJ, Sieper J, Deodhar AA, Colbert RA, Clegg DO. Current controversies in spondyloarthritis: SPARTAN. The Journal of Rheumatology. 37: 2617-23. PMID 21123334 DOI: 10.3899/Jrheum.100890  0.067
2011 Espinoza LR, Reveille JD, Clegg DO. Prologue: 2010 Spondyloarthritis research and therapy network (SPARTAN) annual research and education meeting American Journal of the Medical Sciences. 341: 266-268. PMID 21372664 DOI: 10.1097/MAJ.0b013e31820f8b13  0.065
2011 Davis JF, Choi DL, Schurdak JD, Fitzgerald MF, Clegg DJ, Lipton JW, Figlewicz DP, Benoit SC. Leptin regulates energy balance and motivation through action at distinct neural circuits. Biological Psychiatry. 69: 668-74. PMID 21035790 DOI: 10.1016/J.Biopsych.2010.08.028  0.065
2012 Castañeda TR, Abplanalp W, Um SH, Pfluger PT, Schrott B, Brown K, Grant E, Carnevalli L, Benoit SC, Morgan DA, Gilham D, Hui DY, Rahmouni K, Thomas G, Kozma SC, ... Clegg DJ, et al. Metabolic control by S6 kinases depends on dietary lipids. Plos One. 7: e32631. PMID 22412899 DOI: 10.1371/Journal.Pone.0032631  0.064
2015 Mayor RS, Finch KE, Zehr J, Morselli E, Neinast MD, Frank AP, Hahner LD, Wang J, Rakheja D, Palmer BF, Rosenfeld CR, Savani RC, Clegg DJ. Maternal high fat diet is associated with impaired fetal lung development. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00105.2015. PMID 26092997 DOI: 10.1152/Ajplung.00105.2015  0.064
2015 Bowers CA, Saad D, Clegg DO, Ng P, Clayton F, Haydoura S, Schmidt RH. Rapidly Fatal Internal Carotid Artery Mycotic Aneurysm Rupture in a Rheumatoid Patient Taking a TNF-α Inhibitor: Case Report and Literature Review. Journal of Neurological Surgery. Part a, Central European Neurosurgery. 76: 249-54. PMID 25045858 DOI: 10.1055/s-0034-1372435  0.063
2013 Walsh JA, Duffin KC, Krueger GG, Clegg DO. Limitations in screening instruments for psoriatic arthritis: A comparison of instruments in patients with psoriasis Journal of Rheumatology. 40: 287-293. PMID 23378465 DOI: 10.3899/jrheum.120836  0.063
2012 Manno RL, Bingham CO, Paternotte S, Gossec L, Halhol H, Giacovelli G, Rovati L, Mazzuca SA, Clegg DO, Shi H, Tajana Messi E, Lanzarotti A, Dougados M. OARSI-OMERACT initiative: Defining thresholds for symptomatic severity and structural changes in disease modifying osteoarthritis drug (DMOAD) clinical trials Osteoarthritis and Cartilage. 20: 93-101. PMID 22178465 DOI: 10.1016/j.joca.2011.11.013  0.062
2015 Frank AP, Zechner JF, Clegg DJ. Gastric Bypass Surgery but not Caloric Restriction Improves Reproductive Function in Obese Mice. Obesity Surgery. PMID 26667161 DOI: 10.1007/S11695-015-2009-8  0.062
2011 Park CJ, Zhao Z, Glidewell-Kenney C, Lazic M, Chambon P, Krust A, Weiss J, Clegg DJ, Dunaif A, Jameson JL, Levine JE. Genetic rescue of nonclassical ERα signaling normalizes energy balance in obese Erα-null mutant mice. The Journal of Clinical Investigation. 121: 604-12. PMID 21245576 DOI: 10.1172/Jci41702  0.061
2010 Brown LM, Clegg DJ. Central effects of estradiol in the regulation of food intake, body weight, and adiposity. The Journal of Steroid Biochemistry and Molecular Biology. 122: 65-73. PMID 20035866 DOI: 10.1016/J.Jsbmb.2009.12.005  0.059
2014 Park J, Morley TS, Kim M, Clegg DJ, Scherer PE. Obesity and cancer--mechanisms underlying tumour progression and recurrence. Nature Reviews. Endocrinology. 10: 455-65. PMID 24935119 DOI: 10.1038/Nrendo.2014.94  0.058
2011 Hung M, Clegg DO, Greene T, Saltzman CL. Evaluation of the PROMIS physical function item bank in orthopaedic patients Journal of Orthopaedic Research. 29: 947-953. PMID 21437962 DOI: 10.1002/jor.21308  0.058
2011 Irani BG, Xiang Z, Yarandi HN, Holder JR, Moore MC, Bauzo RM, Proneth B, Shaw AM, Millard WJ, Chambers JB, Benoit SC, Clegg DJ, Haskell-Luevano C. Implication of the melanocortin-3 receptor in the regulation of food intake. European Journal of Pharmacology. 660: 80-7. PMID 21199647 DOI: 10.1016/J.Ejphar.2010.10.101  0.057
2012 Hung M, Clegg DO, Greene T, Weir C, Saltzman CL. A lower extremity physical function computerized adaptive testing instrument for orthopaedic patients. Foot & Ankle International. 33: 326-35. PMID 22735205 DOI: 10.3113/FAI.2012.0326  0.053
2013 Walsh JA, McFadden M, Woodcock J, Clegg DO, Helliwell P, Dommasch E, Gelfand JM, Krueger GG, Duffin KC. Product of the Physician Global Assessment and body surface area: A simple static measure of psoriasis severity in a longitudinal cohort Journal of the American Academy of Dermatology. 69: 931-937. PMID 24054760 DOI: 10.1016/j.jaad.2013.07.040  0.052
2013 Capstick A, Clegg D. Behind the stiff upper lip: War narratives of older men with dementia Journal of War and Culture Studies. 6: 239-254. DOI: 10.1179/1752627213Z.00000000021  0.052
2016 Clegg DL, Rodgers AC. Transitioning unmanned underwater vehicle technology from commercial use to naval Mine Countermeasures operations Oceans 2015 - Mts/Ieee Washington 0.051
2012 Soriano ER, Clegg DO, Lisse JR. Critical appraisal of the guidelines for the management of ankylosing spondylitis: disease-modifying antirheumatic drugs. The American Journal of the Medical Sciences. 343: 357-9. PMID 22543537 DOI: 10.1097/MAJ.0b013e3182513f9c  0.051
2011 Speakman JR, Levitsky DA, Allison DB, Bray MS, de Castro JM, Clegg DJ, Clapham JC, Dulloo AG, Gruer L, Haw S, Hebebrand J, Hetherington MM, Higgs S, Jebb SA, Loos RJ, et al. Set points, settling points and some alternative models: theoretical options to understand how genes and environments combine to regulate body adiposity. Disease Models & Mechanisms. 4: 733-45. PMID 22065844 DOI: 10.1242/Dmm.008698  0.051
2013 Clegg DJ, Palmer BF. Effects of an estrogen receptor α variant. The New England Journal of Medicine. 369: 1663-4. PMID 24152274 DOI: 10.1056/Nejmc1310364  0.051
2011 Benoit SC, Kemp CJ, Elias CF, Abplanalp W, Herman JP, Migrenne S, Lefevre AL, Cruciani-Guglielmacci C, Magnan C, Yu F, Niswender K, Irani BG, Holland WL, Clegg DJ. Palmitic acid mediates hypothalamic insulin resistance by altering PKC-θ subcellular localization in rodents (Journal of Clinical Investigation (2010) 120, 1 (394) DOI: 10.1172/JCI36714C1) Journal of Clinical Investigation. 121: 456. DOI: 10.1172/Jci45846  0.05
2011 Clegg D, van Wijnbergen C. Welfare institutions and the mobilization of consent: Union responses to labour market activation policies in France and the Netherlands European Journal of Industrial Relations. 17: 333-348. DOI: 10.1177/0959680111424661  0.05
2011 Meyer MR, Clegg DJ, Prossnitz ER, Barton M. Obesity, insulin resistance and diabetes: sex differences and role of oestrogen receptors. Acta Physiologica (Oxford, England). 203: 259-69. PMID 21281456 DOI: 10.1111/J.1748-1716.2010.02237.X  0.049
2022 Toh H, Bagheri A, Dewey C, Stewart R, Yan L, Clegg D, Thomson JA, Jiang P. A Nile rat transcriptomic landscape across 22 organs by ultra-deep sequencing and comparative RNA-seq pipeline (CRSP). Computational Biology and Chemistry. 102: 107795. PMID 36436489 DOI: 10.1016/j.compbiolchem.2022.107795  0.049
2010 Reveille JD, Clegg DO. Prologue: 2009 Joint meeting of Spondyloarthritis Research and Therapy Network (SPARTAN) and International Genetics of Ankylosing Spondylitis (IGAS) Journal of Rheumatology. 37: 2604-2605. PMID 21123332 DOI: 10.3899/jrheum.100888  0.048
2012 Clasen J, Clegg D. Unemployment protection and labour market change in Europe: Towards 'triple integration'? Regulating the Risk of Unemployment: National Adaptations to Post-Industrial Labour Markets in Europe. DOI: 10.1093/acprof:oso/9780199592296.003.0001  0.047
2012 Clegg DJ. Minireview: the year in review of estrogen regulation of metabolism. Molecular Endocrinology (Baltimore, Md.). 26: 1957-60. PMID 23051593 DOI: 10.1210/Me.2012-1284  0.047
2012 Hung M, Nickisch F, Beals TC, Greene T, Clegg DO, Saltzman CL. New paradigm for patient-reported outcomes assessment in foot & ankle research: Computerized adaptive testing Foot and Ankle International. 33: 621-626. PMID 22995227 DOI: 10.3113/FAI.2012.0621  0.047
2011 Gossec L, Paternotte S, Bingham CO, Clegg DO, Coste P, Conaghan PG, Davis AM, Giacovelli G, Gunther KP, Hawker G, Hochberg MC, Jordan JM, Katz JN, Kloppenburg M, Lanzarotti A, et al. OARSI/OMERACT initiative to define states of severity and indication for joint replacement in hip and knee osteoarthritis. An OMERACT 10 Special Interest Group. The Journal of Rheumatology. 38: 1765-9. PMID 21807799 DOI: 10.3899/Jrheum.110403  0.045
2010 Plaas A, Clegg DO, Sandy J. Response to Letter to the Editor: 'About oral absorption and human pharmacokinetics of chondroitin sulfate' Osteoarthritis and Cartilage. 18: 1106-1107. DOI: 10.1016/J.Joca.2010.05.011  0.044
2013 Caplan L, Clegg DO, Inman RD. Ankylosing spondylitis clinical registries: principles, practices and possibilities. The American Journal of the Medical Sciences. 345: 437-9. PMID 23841118 DOI: 10.1097/Maj.0B013E3182937335  0.044
2011 Holland WL, Bikman BT, Wang LP, Yuguang G, Sargent KM, Bulchand S, Knotts TA, Shui G, Clegg DJ, Wenk MR, Pagliassotti MJ, Scherer PE, Summers SA. Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice. The Journal of Clinical Investigation. 121: 1858-70. PMID 21490391 DOI: 10.1172/Jci43378  0.043
2023 Anderson BJ, Curtis AM, Jen A, Thomson JA, Clegg DO, Jiang P, Coon JJ, Overmyer KA, Toh H. Plasma metabolomics supports non-fasted sampling for metabolic profiling across a spectrum of glucose tolerance in the Nile rat model for type 2 diabetes. Lab Animal. 52: 269-277. PMID 37857753 DOI: 10.1038/s41684-023-01268-0  0.042
2012 Walsh JA, Duffin KC, Crim J, Clegg DO. Lower frequency of obstructive sleep apnea in spondyloarthritis patients taking TNF-inhibitors Journal of Clinical Sleep Medicine. 8: 643-648. PMID 23243397 DOI: 10.5664/jcsm.2254  0.04
2012 Krikorian R, Shidler MD, Dangelo K, Couch SC, Benoit SC, Clegg DJ. Dietary ketosis enhances memory in mild cognitive impairment. Neurobiology of Aging. 33: 425.e19-27. PMID 21130529 DOI: 10.1016/J.Neurobiolaging.2010.10.006  0.04
2013 Tanner K, Roy N, Merrill RM, Kendall K, Miller KL, Clegg DO, Heller A, Houtz DR, Elstad M. Comparing nebulized water versus saline after laryngeal desiccation challenge in Sjögren's Syndrome. The Laryngoscope. 123: 2787-92. PMID 23674107 DOI: 10.1002/Lary.24148  0.039
2015 Clegg D. The Demise of Tax Credits Political Quarterly. 86: 493-499. DOI: 10.1111/1467-923X.12203  0.038
2010 Sawitzke AD, Shi H, Finco MF, Dunlop DD, Harris CL, Singer NG, Bradley JD, Silver D, Jackson CG, Lane NE, Oddis CV, Wolfe F, Lisse J, Furst DE, Bingham CO, ... ... Clegg DO, et al. Clinical efficacy and safety of glucosamine, chondroitin sulphate, their combination, celecoxib or placebo taken to treat osteoarthritis of the knee: 2-year results from GAIT. Annals of the Rheumatic Diseases. 69: 1459-64. PMID 20525840 DOI: 10.1136/ard.2009.120469  0.037
2012 Clasen J, Clegg D. The transformation of unemployment protection in Europe Regulating the Risk of Unemployment: National Adaptations to Post-Industrial Labour Markets in Europe. DOI: 10.1093/acprof:oso/9780199592296.003.0017  0.037
2012 Clasen J, Clegg D. Regulating the Risk of Unemployment: National Adaptations to Post-Industrial Labour Markets in Europe Regulating the Risk of Unemployment: National Adaptations to Post-Industrial Labour Markets in Europe. 1-432. DOI: 10.1093/acprof:oso/9780199592296.001.0001  0.036
2016 Palmer BF, Clegg DJ. Achieving the Benefits of a High-Potassium, Paleolithic Diet, Without the Toxicity. Mayo Clinic Proceedings. PMID 26948054 DOI: 10.1016/j.mayocp.2016.01.012  0.034
2011 Clegg DJ, Gotoh K, Kemp C, Wortman MD, Benoit SC, Brown LM, D'Alessio D, Tso P, Seeley RJ, Woods SC. Consumption of a high-fat diet induces central insulin resistance independent of adiposity. Physiology & Behavior. 103: 10-6. PMID 21241723 DOI: 10.1016/J.Physbeh.2011.01.010  0.034
2012 Clegg D. France: Integration versus dualization Regulating the Risk of Unemployment: National Adaptations to Post-Industrial Labour Markets in Europe. DOI: 10.1093/acprof:oso/9780199592296.003.0003  0.032
2014 Pennington BO, Sears D, Clegg DO. Interactive Hangman teaches amino acid structures and abbreviations. Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology. 42: 495-500. PMID 25345852 DOI: 10.1002/bmb.20826  0.028
2013 Clasen J, Clegg D. Adapting Labour Market Policy to a Transformed Employment Structure: The Politics of 'Triple Integration' The Politics of the New Welfare State. DOI: 10.1093/acprof:oso/9780199645244.003.0007  0.027
2014 Clegg D. Convergence from below? The reform of minimum income protection in France and the UK Journal of International and Comparative Social Policy. 30: 147-164. DOI: 10.1080/21699763.2014.938683  0.025
2016 Frank AP, Clegg DJ. JAMA PATIENT PAGE. Dietary Guidelines for Americans--Eat Less Sugar. Jama. 315: 1196. PMID 26978223 DOI: 10.1001/Jama.2016.0968  0.024
2014 Clegg D, Young-Mason J. Art, body, and soul, part 2: a conversation with David Clegg. Clinical Nurse Specialist Cns. 28: 121-5. PMID 24504040 DOI: 10.1097/Nur.0000000000000027  0.023
2014 Walsh JA, McFadden ML, Morgan MD, Sawitzke AD, Duffin KC, Krueger GG, Clegg DO. Work productivity loss and fatigue in psoriatic arthritis. The Journal of Rheumatology. 41: 1670-4. PMID 25028377 DOI: 10.3899/jrheum.140259  0.023
2015 Nazarian S, Clegg D, Chang S, Kuriakose J. Difficult diagnosis: internal herniation of the terminal ileum through the foramen of Winslow into the lesser sac. Bmj Case Reports. 2015. PMID 26682837 DOI: 10.1136/bcr-2015-212269  0.022
2015 Palmer BF, Clegg DJ. Electrolyte and Acid-Base Disturbances in Patients with Diabetes Mellitus. The New England Journal of Medicine. 373: 548-59. PMID 26244308 DOI: 10.1056/Nejmra1503102  0.022
2013 Randall JC, Winkler TW, Kutalik Z, Berndt SI, Jackson AU, Monda KL, Kilpeläinen TO, Esko T, Mägi R, Li S, Workalemahu T, Feitosa MF, Croteau-Chonka DC, Day FR, Fall T, ... ... Clegg DJ, et al. Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits. Plos Genetics. 9: e1003500. PMID 23754948 DOI: 10.1371/Journal.Pgen.1003500  0.02
2014 Deodhar A, Reveille JD, van den Bosch F, Braun J, Burgos-Vargas R, Caplan L, Clegg DO, Colbert RA, Gensler LS, van der Heijde D, van der Horst-Bruinsma IE, Inman RD, Maksymowych WP, Mease PJ, Raychaudhuri S, et al. The concept of axial spondyloarthritis: joint statement of the spondyloarthritis research and treatment network and the Assessment of SpondyloArthritis international Society in response to the US Food and Drug Administration's comments and concerns. Arthritis & Rheumatology (Hoboken, N.J.). 66: 2649-56. PMID 25154344 DOI: 10.1002/Art.38776  0.02
2015 Morselli E, Frank AP, Palmer BF, Rodriguez-Navas C, Criollo A, Clegg DJ. A sexually dimorphic hypothalamic response to chronic high-fat diet consumption International Journal of Obesity. DOI: 10.1038/ijo.2015.114  0.016
2012 Kunkel GA, Cannon GW, Clegg DO. Combined structural and synovial assessment for Improved ultrasound Discrimination of rheumatoid, osteoarthritic, and normal joints: A pilot study Open Rheumatology Journal. 6: 199-206. DOI: 10.2174/1874312901206010199  0.016
2015 Clasen J, Clegg D, Goerne A. Comparative Social Policy Analysis and Active Labour Market Policy: Putting Quality before Quantity Journal of Social Policy. 45: 21-38. DOI: 10.1017/S0047279415000434  0.015
2015 Palmer BF, Clegg DJ. Hyperkalemia. Jama. 314: 2405-6. PMID 26647263 DOI: 10.1001/jama.2015.9230  0.014
2014 Assassi S, Weisman MH, Lee M, Savage L, Diekman L, Graham TA, Rahbar MH, Schall JI, Gensler LS, Deodhar AA, Clegg DO, Colbert RA, Reveille JD. New population-based reference values for spinal mobility measures based on the 2009-2010 National Health and Nutrition Examination Survey. Arthritis & Rheumatology (Hoboken, N.J.). 66: 2628-37. PMID 24782356 DOI: 10.1002/Art.38692  0.01
2015 Palmer BF, Clegg DJ. Electrolyte and Acid-Base Disturbances in Diabetes Mellitus. The New England Journal of Medicine. 373: 2482-3. PMID 26672863 DOI: 10.1056/NEJMc1511638  0.01
2015 Walsh JA, Zhou X, Clegg DO, Teng C, Cannon GW, Sauer B. Mortality in American Veterans with the HLA-B27 gene. The Journal of Rheumatology. 42: 638-44. PMID 25684766 DOI: 10.3899/jrheum.140675  0.01
2014 Clegg D. Themed section: Reforming minimum income protection in Europe Journal of International and Comparative Social Policy. 30: 127. DOI: 10.1080/21699763.2014.938946  0.01
2014 Reizes O, Benoit SC, Clegg DJ. Neuroregulation of appetite Treatment of the Obese Patient. 3-22. DOI: 10.1007/978-1-4939-1203-2_1  0.01
2010 Clegg D. From insurance or insertion to rights and responsibilities: The shifting logics of unemployment protection in France Human Rights and Social Policy: a Comparative Analysis of Values and Citizenship in Oecd Countries. 83-100.  0.01
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