Eric Verdin, M.D. - Publications

Affiliations: 
Neuroscience University of California, San Francisco, San Francisco, CA 
Area:
Neuroscience

165 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Wood JG, Schwer B, Wickremesinghe PC, Hartnett DA, Burhenn L, Garcia M, Li M, Verdin E, Helfand SL. Sirt4 is a mitochondrial regulator of metabolism and lifespan in Drosophila melanogaster. Proceedings of the National Academy of Sciences of the United States of America. PMID 29378963 DOI: 10.1073/pnas.1720673115  0.4
2017 Ramachandran D, Clara R, Fedele S, Hu J, Lackzo E, Huang JY, Verdin E, Langhans W, Mansouri A. Intestinal SIRT3 overexpression in mice improves whole body glucose homeostasis independent of body weight. Molecular Metabolism. 6: 1264-1273. PMID 29031725 DOI: 10.1016/j.molmet.2017.07.009  0.32
2016 Besnard E, Hakre S, Kampmann M, Lim HW, Hosmane NN, Martin A, Bassik MC, Verschueren E, Battivelli E, Chan J, Svensson JP, Gramatica A, Conrad RJ, Ott M, Greene WC, ... ... Verdin E, et al. The mTOR Complex Controls HIV Latency. Cell Host & Microbe. 20: 785-797. PMID 27978436 DOI: 10.1016/j.chom.2016.11.001  0.36
2016 Shirakawa K, Wang L, Man N, Maksimoska J, Sorum AW, Lim HW, Lee IS, Shimazu T, Newman JC, Schröder S, Ott M, Marmorstein R, Meier J, Nimer S, Verdin E. Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity. Elife. 5. PMID 27244239 DOI: 10.7554/eLife.11156  0.36
2016 Alhazzazi TY, Kamarajan P, Xu Y, Ai T, Chen L, Verdin E, Kapila YL. A Novel Sirtuin-3 Inhibitor, LC-0296, Inhibits Cell Survival and Proliferation, and Promotes Apoptosis of Head and Neck Cancer Cells. Anticancer Research. 36: 49-60. PMID 26722027  0.76
2015 Verdin E. NAD⁺ in aging, metabolism, and neurodegeneration. Science (New York, N.Y.). 350: 1208-13. PMID 26785480 DOI: 10.1126/science.aac4854  0.76
2015 Wiley CD, Velarde MC, Lecot P, Liu S, Sarnoski EA, Freund A, Shirakawa K, Lim HW, Davis SS, Ramanathan A, Gerencser AA, Verdin E, Campisi J. Mitochondrial Dysfunction Induces Senescence with a Distinct Secretory Phenotype. Cell Metabolism. PMID 26686024 DOI: 10.1016/j.cmet.2015.11.011  0.76
2015 Sundaresan NR, Bindu S, Pillai VB, Samant S, Pan Y, Huang JY, Gupta M, Nagalingam RS, Wolfgeher D, Verdin E, Gupta MP. SIRT3 blocks aging-associated tissue fibrosis in mice by deacetylating and activating GSK3β. Molecular and Cellular Biology. PMID 26667039 DOI: 10.1128/MCB.00586-15  0.76
2015 Rafati H, Parra M, Hakre S, Moshkin Y, Verdin E, Mahmoudi T. Correction: Repressive LTR Nucleosome Positioning by the BAF Complex Is Required for HIV Latency. Plos Biology. 13: e1002302. PMID 26569493 DOI: 10.1371/journal.pbio.1002302  0.76
2015 Min SW, Chen X, Tracy TE, Li Y, Zhou Y, Wang C, Shirakawa K, Minami SS, Defensor E, Mok SA, Sohn PD, Schilling B, Cong X, Ellerby L, Gibson BW, ... ... Verdin E, et al. Critical role of acetylation in tau-mediated neurodegeneration and cognitive deficits. Nature Medicine. PMID 26390242 DOI: 10.1038/nm.3951  0.76
2015 Nishida Y, Rardin MJ, Carrico C, He W, Sahu AK, Gut P, Najjar R, Fitch M, Hellerstein M, Gibson BW, Verdin E. SIRT5 Regulates both Cytosolic and Mitochondrial Protein Malonylation with Glycolysis as a Major Target. Molecular Cell. PMID 26073543 DOI: 10.1016/j.molcel.2015.05.022  0.76
2015 Chavez L, Calvanese V, Verdin E. HIV Latency Is Established Directly and Early in Both Resting and Activated Primary CD4 T Cells. Plos Pathogens. 11: e1004955. PMID 26067822 DOI: 10.1371/journal.ppat.1004955  0.6
2015 Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnölzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, ... ... Verdin E, et al. SIRT1 deacetylates RORγt and enhances Th17 cell generation. The Journal of Experimental Medicine. 212: 973. PMID 25987725 DOI: 10.1084/jem.2013237805062015c  0.36
2015 Lim HW, Kang SG, Ryu JK, Schilling B, Fei M, Lee IS, Kehasse A, Shirakawa K, Yokoyama M, Schnölzer M, Kasler HG, Kwon HS, Gibson BW, Sato H, Akassoglou K, ... ... Verdin E, et al. SIRT1 deacetylates RORγt and enhances Th17 cell generation. The Journal of Experimental Medicine. 212: 607-17. PMID 25918343 DOI: 10.1084/jem.20132378  0.76
2015 Ruelas DS, Chan JK, Oh E, Heidersbach AJ, Hebbeler AM, Chavez L, Verdin E, Rape M, Greene WC. MicroRNA-155 Reinforces HIV Latency. The Journal of Biological Chemistry. 290: 13736-48. PMID 25873391 DOI: 10.1074/jbc.M115.641837  0.76
2015 Zhang Y, Bharathi SS, Rardin MJ, Uppala R, Verdin E, Gibson BW, Goetzman ES. SIRT3 and SIRT5 regulate the enzyme activity and cardiolipin binding of very long-chain acyl-CoA dehydrogenase. Plos One. 10: e0122297. PMID 25811481 DOI: 10.1371/journal.pone.0122297  0.76
2015 Dahabieh MS, Battivelli E, Verdin E. Understanding HIV latency: the road to an HIV cure. Annual Review of Medicine. 66: 407-21. PMID 25587657 DOI: 10.1146/annurev-med-092112-152941  0.76
2015 Verdin E, Ott M. 50 years of protein acetylation: from gene regulation to epigenetics, metabolism and beyond. Nature Reviews. Molecular Cell Biology. 16: 258-64. PMID 25549891 DOI: 10.1038/nrm3931  0.76
2015 Chavez L, Calvanese V, Verdin E. HIV Latency Is Established Directly and Early in Both Resting and Activated Primary CD4 T Cells Plos Pathogens. 11. DOI: 10.1371/journal.ppat.1004955  0.76
2014 Brown KD, Maqsood S, Huang JY, Pan Y, Harkcom W, Li W, Sauve A, Verdin E, Jaffrey SR. Activation of SIRT3 by the NAD⁺ precursor nicotinamide riboside protects from noise-induced hearing loss. Cell Metabolism. 20: 1059-68. PMID 25470550 DOI: 10.1016/j.cmet.2014.11.003  0.76
2014 Newman JC, Verdin E. β-hydroxybutyrate: much more than a metabolite. Diabetes Research and Clinical Practice. 106: 173-81. PMID 25193333 DOI: 10.1016/j.diabres.2014.08.009  0.76
2014 Choudhary C, Weinert BT, Nishida Y, Verdin E, Mann M. The growing landscape of lysine acetylation links metabolism and cell signalling. Nature Reviews. Molecular Cell Biology. 15: 536-50. PMID 25053359 DOI: 10.1038/nrm3841  0.76
2014 Verdin E. The many faces of sirtuins: Coupling of NAD metabolism, sirtuins and lifespan. Nature Medicine. 20: 25-7. PMID 24398962 DOI: 10.1038/nm.3447  0.76
2014 Manson McManamy ME, Hakre S, Verdin EM, Margolis DM. Therapy for latent HIV-1 infection: the role of histone deacetylase inhibitors. Antiviral Chemistry & Chemotherapy. 23: 145-9. PMID 24318952 DOI: 10.3851/IMP2551  0.76
2014 Colin L, Verdin E, Van Lint C. HIV-1 chromatin, transcription, and the regulatory protein Tat. Methods in Molecular Biology (Clifton, N.J.). 1087: 85-101. PMID 24158816 DOI: 10.1007/978-1-62703-670-2_8  0.76
2014 Newman JC, Verdin E. Ketone bodies as signaling metabolites. Trends in Endocrinology and Metabolism: Tem. 25: 42-52. PMID 24140022 DOI: 10.1016/j.tem.2013.09.002  0.76
2013 Spina CA, Anderson J, Archin NM, Bosque A, Chan J, Famiglietti M, Greene WC, Kashuba A, Lewin SR, Margolis DM, Mau M, Ruelas D, Saleh S, Shirakawa K, Siliciano RF, ... ... Verdin E, et al. An in-depth comparison of latent HIV-1 reactivation in multiple cell model systems and resting CD4+ T cells from aviremic patients. Plos Pathogens. 9: e1003834. PMID 24385908 DOI: 10.1371/journal.ppat.1003834  0.76
2013 Rardin MJ, He W, Nishida Y, Newman JC, Carrico C, Danielson SR, Guo A, Gut P, Sahu AK, Li B, Uppala R, Fitch M, Riiff T, Zhu L, Zhou J, ... ... Verdin E, et al. SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks. Cell Metabolism. 18: 920-33. PMID 24315375 DOI: 10.1016/j.cmet.2013.11.013  0.76
2013 Ho L, Titus AS, Banerjee KK, George S, Lin W, Deota S, Saha AK, Nakamura K, Gut P, Verdin E, Kolthur-Seetharam U. SIRT4 regulates ATP homeostasis and mediates a retrograde signaling via AMPK. Aging. 5: 835-49. PMID 24296486  0.76
2013 Novis CL, Archin NM, Buzon MJ, Verdin E, Round JL, Lichterfeld M, Margolis DM, Planelles V, Bosque A. Reactivation of latent HIV-1 in central memory CD4⁺ T cells through TLR-1/2 stimulation. Retrovirology. 10: 119. PMID 24156240 DOI: 10.1186/1742-4690-10-119  0.76
2013 Gut P, Verdin E. The nexus of chromatin regulation and intermediary metabolism. Nature. 502: 489-98. PMID 24153302 DOI: 10.1038/nature12752  0.76
2013 Bharathi SS, Zhang Y, Mohsen AW, Uppala R, Balasubramani M, Schreiber E, Uechi G, Beck ME, Rardin MJ, Vockley J, Verdin E, Gibson BW, Hirschey MD, Goetzman ES. Sirtuin 3 (SIRT3) protein regulates long-chain acyl-CoA dehydrogenase by deacetylating conserved lysines near the active site. The Journal of Biological Chemistry. 288: 33837-47. PMID 24121500 DOI: 10.1074/jbc.M113.510354  0.76
2013 Calvanese V, Chavez L, Laurent T, Ding S, Verdin E. Dual-color HIV reporters trace a population of latently infected cells and enable their purification. Virology. 446: 283-92. PMID 24074592 DOI: 10.1016/j.virol.2013.07.037  0.76
2013 Alhazzazi TY, Kamarajan P, Verdin E, Kapila YL. Sirtuin-3 (SIRT3) and the Hallmarks of Cancer. Genes & Cancer. 4: 164-71. PMID 24020007 DOI: 10.1177/1947601913486351  0.76
2013 Verdin E, Ott M. Acetylphosphate: a novel link between lysine acetylation and intermediary metabolism in bacteria. Molecular Cell. 51: 132-4. PMID 23870140 DOI: 10.1016/j.molcel.2013.07.006  0.76
2013 Jing E, O'Neill BT, Rardin MJ, Kleinridders A, Ilkeyeva OR, Ussar S, Bain JR, Lee KY, Verdin EM, Newgard CB, Gibson BW, Kahn CR. Sirt3 regulates metabolic flexibility of skeletal muscle through reversible enzymatic deacetylation. Diabetes. 62: 3404-17. PMID 23835326 DOI: 10.2337/db12-1650  0.76
2013 Kang SG, Liu WH, Lu P, Jin HY, Lim HW, Shepherd J, Fremgen D, Verdin E, Oldstone MB, Qi H, Teijaro JR, Xiao C. MicroRNAs of the miR-17∼92 family are critical regulators of T(FH) differentiation. Nature Immunology. 14: 849-57. PMID 23812097 DOI: 10.1038/ni.2648  0.76
2013 Ott M, Verdin E. Three rules for HIV latency: location, location, and location. Cell Host & Microbe. 13: 625-6. PMID 23768485 DOI: 10.1016/j.chom.2013.05.016  0.76
2013 Gut P, Verdin E. Rejuvenating SIRT1 activators. Cell Metabolism. 17: 635-7. PMID 23663735 DOI: 10.1016/j.cmet.2013.04.016  0.76
2013 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW. Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proceedings of the National Academy of Sciences of the United States of America. 110: 6601-6. PMID 23576753 DOI: 10.1073/pnas.1302961110  0.76
2013 Shirakawa K, Chavez L, Hakre S, Calvanese V, Verdin E. Reactivation of latent HIV by histone deacetylase inhibitors. Trends in Microbiology. 21: 277-85. PMID 23517573 DOI: 10.1016/j.tim.2013.02.005  0.76
2013 Merksamer PI, Liu Y, He W, Hirschey MD, Chen D, Verdin E. The sirtuins, oxidative stress and aging: an emerging link. Aging. 5: 144-50. PMID 23474711  0.76
2013 Wirth M, Karaca S, Wenzel D, Ho L, Tishkoff D, Lombard DB, Verdin E, Urlaub H, Jedrusik-Bode M, Fischle W. Mitochondrial SIRT4-type proteins in Caenorhabditis elegans and mammals interact with pyruvate carboxylase and other acetylated biotin-dependent carboxylases. Mitochondrion. 13: 705-20. PMID 23438705 DOI: 10.1016/j.mito.2013.02.002  0.76
2013 Boehm D, Calvanese V, Dar RD, Xing S, Schroeder S, Martins L, Aull K, Li PC, Planelles V, Bradner JE, Zhou MM, Siliciano RF, Weinberger L, Verdin E, Ott M. BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism. Cell Cycle (Georgetown, Tex.). 12: 452-62. PMID 23255218 DOI: 10.4161/cc.23309  0.76
2013 Shimazu T, Hirschey MD, Newman J, He W, Shirakawa K, Le Moan N, Grueter CA, Lim H, Saunders LR, Stevens RD, Newgard CB, Farese RV, de Cabo R, Ulrich S, Akassoglou K, ... Verdin E, et al. Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. Science (New York, N.Y.). 339: 211-4. PMID 23223453 DOI: 10.1126/science.1227166  0.76
2013 Gut P, Baeza-Raja B, Andersson O, Hasenkamp L, Hsiao J, Hesselson D, Akassoglou K, Verdin E, Hirschey MD, Stainier DY. Whole-organism screening for gluconeogenesis identifies activators of fasting metabolism. Nature Chemical Biology. 9: 97-104. PMID 23201900 DOI: 10.1038/nchembio.1136  0.76
2012 Sinclair D, Verdin E. The longevity of sirtuins. Cell Reports. 2: 1473-4. PMID 23273894 DOI: 10.1016/j.celrep.2012.12.004  0.76
2012 Weir HJ, Murray TK, Kehoe PG, Love S, Verdin EM, O'Neill MJ, Lane JD, Balthasar N. CNS SIRT3 expression is altered by reactive oxygen species and in Alzheimer's disease. Plos One. 7: e48225. PMID 23139766 DOI: 10.1371/journal.pone.0048225  0.76
2012 Kasler HG, Lim HW, Mottet D, Collins AM, Lee IS, Verdin E. Nuclear export of histone deacetylase 7 during thymic selection is required for immune self-tolerance. The Embo Journal. 31: 4453-65. PMID 23103766 DOI: 10.1038/emboj.2012.295  0.76
2012 Newman JC, He W, Verdin E. Mitochondrial protein acylation and intermediary metabolism: regulation by sirtuins and implications for metabolic disease. The Journal of Biological Chemistry. 287: 42436-43. PMID 23086951 DOI: 10.1074/jbc.R112.404863  0.76
2012 Bonezzi K, Belotti D, North BJ, Ghilardi C, Borsotti P, Resovi A, Ubezio P, Riva A, Giavazzi R, Verdin E, Taraboletti G. Inhibition of SIRT2 potentiates the anti-motility activity of taxanes: implications for antineoplastic combination therapies. Neoplasia (New York, N.Y.). 14: 846-54. PMID 23019416 DOI: 10.1593/neo.12728  0.76
2012 Pan Y, Nishida Y, Wang M, Verdin E. Metabolic regulation, mitochondria and the life-prolonging effect of rapamycin: a mini-review. Gerontology. 58: 524-30. PMID 22947849 DOI: 10.1159/000342204  0.76
2012 He W, Newman JC, Wang MZ, Ho L, Verdin E. Mitochondrial sirtuins: regulators of protein acylation and metabolism. Trends in Endocrinology and Metabolism: Tem. 23: 467-76. PMID 22902903 DOI: 10.1016/j.tem.2012.07.004  0.76
2012 Deeks SG, Autran B, Berkhout B, Benkirane M, Cairns S, Chomont N, Chun TW, Churchill M, Di Mascio M, Katlama C, Lafeuillade A, Landay A, Lederman M, Lewin SR, ... ... Verdin E, et al. Towards an HIV cure: a global scientific strategy. Nature Reviews. Immunology. 12: 607-14. PMID 22814509 DOI: 10.1038/nri3262  0.76
2012 Kamarajan P, Alhazzazi TY, Danciu T, D'silva NJ, Verdin E, Kapila YL. Receptor-interacting protein (RIP) and Sirtuin-3 (SIRT3) are on opposite sides of anoikis and tumorigenesis. Cancer. 118: 5800-10. PMID 22674009 DOI: 10.1002/cncr.27655  0.76
2012 Jang YC, Liu Y, Hayworth CR, Bhattacharya A, Lustgarten MS, Muller FL, Chaudhuri A, Qi W, Li Y, Huang JY, Verdin E, Richardson A, Van Remmen H. Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD. Aging Cell. 11: 770-82. PMID 22672615 DOI: 10.1111/j.1474-9726.2012.00843.x  0.76
2012 Deeks SG, Verdin E, McCune JM. Immunosenescence and HIV. Current Opinion in Immunology. 24: 501-6. PMID 22658763 DOI: 10.1016/j.coi.2012.05.004  0.76
2012 Ismail H, Mofarrahi M, Echavarria R, Harel S, Verdin E, Lim HW, Jin ZG, Sun J, Zeng H, Hussain SN. Angiopoietin-1 and vascular endothelial growth factor regulation of leukocyte adhesion to endothelial cells: role of nuclear receptor-77. Arteriosclerosis, Thrombosis, and Vascular Biology. 32: 1707-16. PMID 22628435 DOI: 10.1161/ATVBAHA.112.251546  0.76
2012 Schilling B, Rardin MJ, MacLean BX, Zawadzka AM, Frewen BE, Cusack MP, Sorensen DJ, Bereman MS, Jing E, Wu CC, Verdin E, Kahn CR, Maccoss MJ, Gibson BW. Platform-independent and label-free quantitation of proteomic data using MS1 extracted ion chromatograms in skyline: application to protein acetylation and phosphorylation. Molecular & Cellular Proteomics : McP. 11: 202-14. PMID 22454539 DOI: 10.1074/mcp.M112.017707  0.76
2012 Hakre S, Chavez L, Shirakawa K, Verdin E. HIV latency: experimental systems and molecular models. Fems Microbiology Reviews. 36: 706-16. PMID 22372374 DOI: 10.1111/j.1574-6976.2012.00335.x  0.76
2012 Kwon HS, Lim HW, Wu J, Schnölzer M, Verdin E, Ott M. Three novel acetylation sites in the Foxp3 transcription factor regulate the suppressive activity of regulatory T cells. Journal of Immunology (Baltimore, Md. : 1950). 188: 2712-21. PMID 22312127 DOI: 10.4049/jimmunol.1100903  0.76
2012 Fritz KS, Galligan JJ, Hirschey MD, Verdin E, Petersen DR. Mitochondrial acetylome analysis in a mouse model of alcohol-induced liver injury utilizing SIRT3 knockout mice. Journal of Proteome Research. 11: 1633-43. PMID 22309199 DOI: 10.1021/pr2008384  0.76
2012 Peixoto P, Castronovo V, Matheus N, Polese C, Peulen O, Gonzalez A, Boxus M, Verdin E, Thiry M, Dequiedt F, Mottet D. HDAC5 is required for maintenance of pericentric heterochromatin, and controls cell-cycle progression and survival of human cancer cells Cell Death and Differentiation. 19: 1239-1252. PMID 22301920 DOI: 10.1038/cdd.2012.3  0.76
2012 Streeper RS, Grueter CA, Salomonis N, Cases S, Levin MC, Koliwad SK, Zhou P, Hirschey MD, Verdin E, Farese RV. Deficiency of the lipid synthesis enzyme, DGAT1, extends longevity in mice. Aging. 4: 13-27. PMID 22291164  0.76
2012 Gallastegui E, Marshall B, Vidal D, Sanchez-Duffhues G, Collado JA, Alvarez-Fernández C, Luque N, Terme JM, Gatell JM, Sánchez-Palomino S, Muñoz E, Mestres J, Verdin E, Jordan A. Combination of biological screening in a cellular model of viral latency and virtual screening identifies novel compounds that reactivate HIV-1. Journal of Virology. 86: 3795-808. PMID 22258251 DOI: 10.1128/JVI.05972-11  0.76
2012 Schröder S, Cho S, Zeng L, Zhang Q, Kaehlcke K, Mak L, Lau J, Bisgrove D, Schnölzer M, Verdin E, Zhou MM, Ott M. Two-pronged binding with bromodomain-containing protein 4 liberates positive transcription elongation factor b from inactive ribonucleoprotein complexes. The Journal of Biological Chemistry. 287: 1090-9. PMID 22084242 DOI: 10.1074/jbc.M111.282855  0.76
2012 Maurer B, Rumpf T, Scharfe M, Stolfa DA, Schmitt ML, He W, Verdin E, Sippl W, Jung M. Inhibitors of the NAD+-dependent protein desuccinylase and demalonylase sirt5 Acs Medicinal Chemistry Letters. 3: 1050-1053. DOI: 10.1021/ml3002709  0.76
2011 Rafati H, Parra M, Hakre S, Moshkin Y, Verdin E, Mahmoudi T. Repressive LTR nucleosome positioning by the BAF complex is required for HIV latency. Plos Biology. 9: e1001206. PMID 22140357 DOI: 10.1371/journal.pbio.1001206  0.76
2011 Hirschey MD, Shimazu T, Huang JY, Schwer B, Verdin E. SIRT3 regulates mitochondrial protein acetylation and intermediary metabolism. Cold Spring Harbor Symposia On Quantitative Biology. 76: 267-77. PMID 22114326 DOI: 10.1101/sqb.2011.76.010850  0.76
2011 Peng C, Lu Z, Xie Z, Cheng Z, Chen Y, Tan M, Luo H, Zhang Y, He W, Yang K, Zwaans BM, Tishkoff D, Ho L, Lombard D, He TC, ... ... Verdin E, et al. The first identification of lysine malonylation substrates and its regulatory enzyme. Molecular & Cellular Proteomics : McP. 10: M111.012658. PMID 21908771 DOI: 10.1074/mcp.M111.012658  0.76
2011 Jing E, Emanuelli B, Hirschey MD, Boucher J, Lee KY, Lombard D, Verdin EM, Kahn CR. Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production. Proceedings of the National Academy of Sciences of the United States of America. 108: 14608-13. PMID 21873205 DOI: 10.1073/pnas.1111308108  0.76
2011 Hirschey MD, Shimazu T, Jing E, Grueter CA, Collins AM, Aouizerat B, Stančáková A, Goetzman E, Lam MM, Schwer B, Stevens RD, Muehlbauer MJ, Kakar S, Bass NM, Kuusisto J, ... ... Verdin E, et al. SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome. Molecular Cell. 44: 177-90. PMID 21856199 DOI: 10.1016/j.molcel.2011.07.019  0.76
2011 Hirschey MD, Shimazu T, Capra JA, Pollard KS, Verdin E. SIRT1 and SIRT3 deacetylate homologous substrates: AceCS1,2 and HMGCS1,2 Aging. 3: 635-642. PMID 21701047  0.76
2011 Alhazzazi TY, Kamarajan P, Verdin E, Kapila YL. SIRT3 and cancer: tumor promoter or suppressor? Biochimica Et Biophysica Acta. 1816: 80-8. PMID 21586315 DOI: 10.1016/j.bbcan.2011.04.004  0.76
2011 Alhazzazi TY, Kamarajan P, Joo N, Huang JY, Verdin E, D'Silva NJ, Kapila YL. Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer. Cancer. 117: 1670-8. PMID 21472714 DOI: 10.1002/cncr.25676  0.76
2011 Kasler HG, Young BD, Mottet D, Lim HW, Collins AM, Olson EN, Verdin E. Histone deacetylase 7 regulates cell survival and TCR signaling in CD4/CD8 double-positive thymocytes. Journal of Immunology (Baltimore, Md. : 1950). 186: 4782-93. PMID 21398603 DOI: 10.4049/jimmunol.1001179  0.76
2011 Hakre S, Chavez L, Shirakawa K, Verdin E. Epigenetic regulation of HIV latency. Current Opinion in Hiv and Aids. 6: 19-24. PMID 21242889 DOI: 10.1097/COH.0b013e3283412384  0.76
2011 Chávez L, Kauder S, Verdin E. In vivo, in vitro, and in silico analysis of methylation of the HIV-1 provirus. Methods (San Diego, Calif.). 53: 47-53. PMID 20670606 DOI: 10.1016/j.ymeth.2010.05.009  0.76
2010 Qiu X, Brown K, Hirschey MD, Verdin E, Chen D. Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation. Cell Metabolism. 12: 662-7. PMID 21109198 DOI: 10.1016/j.cmet.2010.11.015  0.76
2010 Shimazu T, Hirschey MD, Hua L, Dittenhafer-Reed KE, Schwer B, Lombard DB, Li Y, Bunkenborg J, Alt FW, Denu JM, Jacobson MP, Verdin E. SIRT3 deacetylates mitochondrial 3-hydroxy-3-methylglutaryl CoA synthase 2 and regulates ketone body production. Cell Metabolism. 12: 654-61. PMID 21109197 DOI: 10.1016/j.cmet.2010.11.003  0.76
2010 Verdin E, Hirschey MD, Finley LW, Haigis MC. Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling. Trends in Biochemical Sciences. 35: 669-75. PMID 20863707 DOI: 10.1016/j.tibs.2010.07.003  0.76
2010 Baur JA, Chen D, Chini EN, Chua K, Cohen HY, de Cabo R, Deng C, Dimmeler S, Gius D, Guarente LP, Helfand SL, Imai S, Itoh H, Kadowaki T, Koya D, ... ... Verdin E, et al. Dietary restriction: standing up for sirtuins. Science (New York, N.Y.). 329: 1012-3; author reply. PMID 20798296 DOI: 10.1126/science.329.5995.1012  0.76
2010 Yan W, Si Y, Slaymaker S, Li J, Zheng H, Young DL, Aslanian A, Saunders L, Verdin E, Charo IF. Zmynd15 encodes a histone deacetylase-dependent transcriptional repressor essential for spermiogenesis and male fertility. The Journal of Biological Chemistry. 285: 31418-26. PMID 20675388 DOI: 10.1074/jbc.M110.116418  0.76
2010 Saunders LR, Sharma AD, Tawney J, Nakagawa M, Okita K, Yamanaka S, Willenbring H, Verdin E. miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues. Aging. 2: 415-31. PMID 20634564 DOI: v2/n7/full/100176.html  0.76
2010 Trono D, Van Lint C, Rouzioux C, Verdin E, Barré-Sinoussi F, Chun TW, Chomont N. HIV persistence and the prospect of long-term drug-free remissions for hiv-infected individuals Science. 329: 174-180. PMID 20616270 DOI: 10.1126/science.1191047  0.76
2010 Ott M, Verdin E. HAT trick: p300, small molecule, inhibitor. Chemistry & Biology. 17: 417-8. PMID 20534339 DOI: 10.1016/j.chembiol.2010.05.002  0.76
2010 Shimazu T, Hirschey MD, Huang JY, Ho LT, Verdin E. Acetate metabolism and aging: An emerging connection. Mechanisms of Ageing and Development. 131: 511-6. PMID 20478325 DOI: 10.1016/j.mad.2010.05.001  0.76
2010 Parra M, Verdin E. Regulatory signal transduction pathways for class IIa histone deacetylases. Current Opinion in Pharmacology. 10: 454-60. PMID 20447866 DOI: 10.1016/j.coph.2010.04.004  0.76
2010 Blagosklonny MV, Campisi J, Sinclair DA, Bartke A, Blasco MA, Bonner WM, Bohr VA, Brosh RM, Brunet A, Depinho RA, Donehower LA, Finch CE, Finkel T, Gorospe M, Gudkov AV, ... ... Verdin E, et al. Impact papers on aging in 2009. Aging. 2: 111-21. PMID 20351400 DOI: v2/n3/full/100132.html  0.76
2010 Pagans S, Kauder SE, Kaehlcke K, Sakane N, Schroeder S, Dormeyer W, Trievel RC, Verdin E, Schnolzer M, Ott M. The Cellular lysine methyltransferase Set7/9-KMT7 binds HIV-1 TAR RNA, monomethylates the viral transactivator Tat, and enhances HIV transcription. Cell Host & Microbe. 7: 234-44. PMID 20227666 DOI: 10.1016/j.chom.2010.02.005  0.76
2010 Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, ... ... Verdin E, et al. SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation. Nature. 464: 121-5. PMID 20203611 DOI: 10.1038/nature08778  0.76
2010 Huang JY, Hirschey MD, Shimazu T, Ho L, Verdin E. Mitochondrial sirtuins. Biochimica Et Biophysica Acta. 1804: 1645-51. PMID 20060508 DOI: 10.1016/j.bbapap.2009.12.021  0.76
2010 Malik S, Jiang S, Garee JP, Verdin E, Lee AV, O'Malley BW, Zhang M, Belaguli NS, Oesterreich S. Histone deacetylase 7 and FoxA1 in estrogen-mediated repression of RPRM. Molecular and Cellular Biology. 30: 399-412. PMID 19917725 DOI: 10.1128/MCB.00907-09  0.76
2009 Blazkova J, Trejbalova K, Gondois-Rey F, Halfon P, Philibert P, Guiguen A, Verdin E, Olive D, Van Lint C, Hejnar J, Hirsch I. CpG methylation controls reactivation of HIV from latency. Plos Pathogens. 5: e1000554. PMID 19696893 DOI: 10.1371/journal.ppat.1000554  0.76
2009 Kauder SE, Bosque A, Lindqvist A, Planelles V, Verdin E. Epigenetic regulation of HIV-1 latency by cytosine methylation. Plos Pathogens. 5: e1000495. PMID 19557157 DOI: 10.1371/journal.ppat.1000495  0.76
2009 Hirschey MD, Shimazu T, Huang JY, Verdin E. Acetylation of mitochondrial proteins. Methods in Enzymology. 457: 137-47. PMID 19426866 DOI: 10.1016/S0076-6879(09)05008-3  0.76
2009 Cooper HM, Huang JY, Verdin E, Spelbrink JN. A new splice variant of the mouse SIRT3 gene encodes the mitochondrial precursor protein. Plos One. 4: e4986. PMID 19333382 DOI: 10.1371/journal.pone.0004986  0.76
2009 Saunders LR, Verdin E. Cell biology. Stress response and aging. Science (New York, N.Y.). 323: 1021-2. PMID 19229027 DOI: 10.1126/science.1170007  0.76
2009 Pintchovski SA, Peebles CL, Kim HJ, Verdin E, Finkbeiner S. The serum response factor and a putative novel transcription factor regulate expression of the immediate-early gene Arc/Arg3.1 in neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 1525-37. PMID 19193899 DOI: 10.1523/JNEUROSCI.5575-08.2009  0.76
2009 Schäfer S, Saunders L, Schlimme S, Valkov V, Wagner JM, Kratz F, Sippl W, Verdin E, Jung M. Pyridylalanine-containing hydroxamic acids as selective HDAC6 inhibitors Chemmedchem. 4: 283-290. PMID 19090524 DOI: 10.1002/cmdc.200800196  0.76
2009 Mottet D, Pirotte S, Lamour V, Hagedorn M, Javerzat S, Bikfalvi A, Bellahcène A, Verdin E, Castronovo V. HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanism. Oncogene. 28: 243-56. PMID 18850004 DOI: 10.1038/onc.2008.371  0.76
2008 Verdin E. Regulation of human immunodeficiency virus-1 latency and its reactivation Bulletin Et MéMoires De L'AcadéMie Royale De MéDecine De Belgique. 163: 355-364; discussion . PMID 19445107  0.76
2008 Uciechowska U, Schemies J, Neugebauer RC, Huda EM, Schmitt ML, Meier R, Verdin E, Jung M, Sippl W. Thiobarbiturates as sirtuin inhibitors: virtual screening, free-energy calculations, and biological testing. Chemmedchem. 3: 1965-76. PMID 18985648 DOI: 10.1002/cmdc.200800104  0.76
2008 Scott GK, Marx C, Berger CE, Saunders LR, Verdin E, Schäfer S, Jung M, Benz CC. Destabilization of ERBB2 transcripts by targeting 3' untranslated region messenger RNA associated HuR and histone deacetylase-6. Molecular Cancer Research : McR. 6: 1250-8. PMID 18644987 DOI: 10.1158/1541-7786.MCR-07-2110  0.76
2008 Wang S, Li X, Parra M, Verdin E, Bassel-Duby R, Olson EN. Control of endothelial cell proliferation and migration by VEGF signaling to histone deacetylase 7. Proceedings of the National Academy of Sciences of the United States of America. 105: 7738-43. PMID 18509061 DOI: 10.1073/pnas.0802857105  0.76
2008 Neugebauer RC, Uchiechowska U, Meier R, Hruby H, Valkov V, Verdin E, Sippl W, Jung M. Structure-activity studies on splitomicin derivatives as sirtuin inhibitors and computational prediction of binding mode. Journal of Medicinal Chemistry. 51: 1203-13. PMID 18269226 DOI: 10.1021/jm700972e  0.76
2008 Schwer B, Verdin E. Conserved metabolic regulatory functions of sirtuins. Cell Metabolism. 7: 104-12. PMID 18249170 DOI: 10.1016/j.cmet.2007.11.006  0.76
2008 Schäfer S, Saunders L, Eliseeva E, Velena A, Jung M, Schwienhorst A, Strasser A, Dickmanns A, Ficner R, Schlimme S, Sippl W, Verdin E, Jung M. Phenylalanine-containing hydroxamic acids as selective inhibitors of class IIb histone deacetylases (HDACs). Bioorganic & Medicinal Chemistry. 16: 2011-33. PMID 18054239 DOI: 10.1016/j.bmc.2007.10.092  0.76
2007 Verdin E. AROuSing SIRT1: identification of a novel endogenous SIRT1 activator. Molecular Cell. 28: 354-6. PMID 17996699 DOI: 10.1016/j.molcel.2007.10.013  0.76
2007 Lombard DB, Alt FW, Cheng HL, Bunkenborg J, Streeper RS, Mostoslavsky R, Kim J, Yancopoulos G, Valenzuela D, Murphy A, Yang Y, Chen Y, Hirschey MD, Bronson RT, Haigis M, ... ... Verdin E, et al. Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation. Molecular and Cellular Biology. 27: 8807-14. PMID 17923681 DOI: 10.1128/MCB.01636-07  0.76
2007 North BJ, Verdin E. Interphase nucleo-cytoplasmic shuttling and localization of SIRT2 during mitosis. Plos One. 2: e784. PMID 17726514 DOI: 10.1371/journal.pone.0000784  0.76
2007 Ahuja N, Schwer B, Carobbio S, Waltregny D, North BJ, Castronovo V, Maechler P, Verdin E. Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase. The Journal of Biological Chemistry. 282: 33583-92. PMID 17715127 DOI: 10.1074/jbc.M705488200  0.76
2007 Saunders LR, Verdin E. Sirtuins: critical regulators at the crossroads between cancer and aging. Oncogene. 26: 5489-504. PMID 17694089 DOI: 10.1038/sj.onc.1210616  0.76
2007 Bisgrove DA, Mahmoudi T, Henklein P, Verdin E. Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription. Proceedings of the National Academy of Sciences of the United States of America. 104: 13690-5. PMID 17690245 DOI: 10.1073/pnas.0705053104  0.76
2007 North BJ, Verdin E. Mitotic regulation of SIRT2 by cyclin-dependent kinase 1-dependent phosphorylation. The Journal of Biological Chemistry. 282: 19546-55. PMID 17488717 DOI: 10.1074/jbc.M702990200  0.76
2007 Kasler HG, Verdin E. Histone deacetylase 7 functions as a key regulator of genes involved in both positive and negative selection of thymocytes. Molecular and Cellular Biology. 27: 5184-200. PMID 17470548 DOI: 10.1128/MCB.02091-06  0.76
2007 Pagan JK, Arnold J, Hanchard KJ, Kumar R, Bruno T, Jones MJ, Richard DJ, Forrest A, Spurdle A, Verdin E, Crossley M, Fanciulli M, Chenevix-Trench G, Young DB, Khanna KK. A novel corepressor, BCoR-L1, represses transcription through an interaction with CtBP. The Journal of Biological Chemistry. 282: 15248-57. PMID 17379597 DOI: 10.1074/jbc.M700246200  0.76
2007 Barrett A, Santangelo S, Tan K, Catchpole S, Roberts K, Spencer-Dene B, Hall D, Scibetta A, Burchell J, Verdin E, Freemont P, Taylor-Papadimitriou J. Breast cancer associated transcriptional repressor PLU-1/JARID1B interacts directly with histone deacetylases. International Journal of Cancer. Journal International Du Cancer. 121: 265-75. PMID 17373667 DOI: 10.1002/ijc.22673  0.76
2007 Parra M, Mahmoudi T, Verdin E. Myosin phosphatase dephosphorylates HDAC7, controls its nucleocytoplasmic shuttling, and inhibits apoptosis in thymocytes. Genes & Development. 21: 638-43. PMID 17369396 DOI: 10.1101/gad.1513107  0.76
2007 Krennhrubec K, Marshall BL, Hedglin M, Verdin E, Ulrich SM. Design and evaluation of 'Linkerless' hydroxamic acids as selective HDAC8 inhibitors. Bioorganic & Medicinal Chemistry Letters. 17: 2874-8. PMID 17346959 DOI: 10.1016/j.bmcl.2007.02.064  0.76
2007 Ohnuma-Ishikawa K, Morio T, Yamada T, Sugawara Y, Ono M, Nagasawa M, Yasuda A, Morimoto C, Ohnuma K, Dang NH, Hosoi H, Verdin E, Mizutani S. Knockdown of XAB2 enhances all-trans retinoic acid-induced cellular differentiation in all-trans retinoic acid-sensitive and -resistant cancer cells. Cancer Research. 67: 1019-29. PMID 17283134 DOI: 10.1158/0008-5472.CAN-06-1638  0.76
2006 Trapp J, Jochum A, Meier R, Saunders L, Marshall B, Kunick C, Verdin E, Goekjian P, Sippl W, Jung M. Adenosine mimetics as inhibitors of NAD+-dependent histone deacetylases, from kinase to sirtuin inhibition. Journal of Medicinal Chemistry. 49: 7307-16. PMID 17149860 DOI: 10.1021/jm060118b  0.76
2006 Saunders LR, Verdin E. Ornithine decarboxylase activity in tumor cell lines correlates with sensitivity to cell death induced by histone deacetylase inhibitors. Molecular Cancer Therapeutics. 5: 2777-85. PMID 17121924 DOI: 10.1158/1535-7163.MCT-06-0298  0.76
2006 Schwer B, Bunkenborg J, Verdin RO, Andersen JS, Verdin E. Reversible lysine acetylation controls the activity of the mitochondrial enzyme acetyl-CoA synthetase 2. Proceedings of the National Academy of Sciences of the United States of America. 103: 10224-9. PMID 16788062 DOI: 10.1073/pnas.0603968103  0.76
2006 Mahmoudi T, Parra M, Vries RG, Kauder SE, Verrijzer CP, Ott M, Verdin E. The SWI/SNF chromatin-remodeling complex is a cofactor for Tat transactivation of the HIV promoter. The Journal of Biological Chemistry. 281: 19960-8. PMID 16687403 DOI: 10.1074/jbc.M603336200  0.76
2006 Williams SA, Chen LF, Kwon H, Ruiz-Jarabo CM, Verdin E, Greene WC. NF-kappaB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation. The Embo Journal. 25: 139-49. PMID 16319923 DOI: 10.1038/sj.emboj.7600900  0.76
2005 Olaharski AJ, Rine J, Marshall BL, Babiarz J, Zhang L, Verdin E, Smith MT. The flavoring agent dihydrocoumarin reverses epigenetic silencing and inhibits sirtuin deacetylases Plos Genetics. 1: e77. PMID 16362078 DOI: 10.1371/journal.pgen.0010077  0.76
2005 Bisgrove D, Lewinski M, Bushman F, Verdin E. Molecular mechanisms of HIV-1 proviral latency. Expert Review of Anti-Infective Therapy. 3: 805-14. PMID 16207172 DOI: 10.1586/14787210.3.5.805  0.76
2005 North BJ, Schwer B, Ahuja N, Marshall B, Verdin E. Preparation of enzymatically active recombinant class III protein deacetylases. Methods (San Diego, Calif.). 36: 338-45. PMID 16091304 DOI: 10.1016/j.ymeth.2005.03.004  0.76
2005 Wittich S, Scherf H, Xie C, Heltweg B, Dequiedt F, Verdin E, Gerhäuser C, Jung M. Effect of inhibitors of histone deacetylase on the induction of cell differentiation in murine and human erythroleukemia cell lines Anti-Cancer Drugs. 16: 635-643. PMID 15930892 DOI: 10.1097/00001813-200507000-00008  0.76
2005 Lewinski MK, Bisgrove D, Shinn P, Chen H, Hoffmann C, Hannenhalli S, Verdin E, Berry CC, Ecker JR, Bushman FD. Genome-wide analysis of chromosomal features repressing human immunodeficiency virus transcription. Journal of Virology. 79: 6610-9. PMID 15890899 DOI: 10.1128/JVI.79.11.6610-6619.2005  0.76
2005 Jayakumar P, Berger I, Autschbach F, Weinstein M, Funke B, Verdin E, Goldsmith MA, Keppler OT. Tissue-resident macrophages are productively infected ex vivo by primary X4 isolates of human immunodeficiency virus type 1. Journal of Virology. 79: 5220-6. PMID 15795306 DOI: 10.1128/JVI.79.8.5220-5226.2005  0.76
2005 Waltregny D, Glénisson W, Tran SL, North BJ, Verdin E, Colige A, Castronovo V. Histone deacetylase HDAC8 associates with smooth muscle alpha-actin and is essential for smooth muscle cell contractility. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 966-8. PMID 15772115 DOI: 10.1096/fj.04-2303fje  0.76
2005 Pagans S, Pedal A, North BJ, Kaehlcke K, Marshall BL, Dorr A, Hetzer-Egger C, Henklein P, Frye R, McBurney MW, Hruby H, Jung M, Verdin E, Ott M. SIRT1 regulates HIV transcription via Tat deacetylation. Plos Biology. 3: e41. PMID 15719057 DOI: 10.1371/journal.pbio.0030041  0.76
2005 Parra M, Kasler H, McKinsey TA, Olson EN, Verdin E. Protein kinase D1 phosphorylates HDAC7 and induces its nuclear export after T-cell receptor activation Journal of Biological Chemistry. 280: 13762-13770. PMID 15623513 DOI: 10.1074/jbc.M413396200  0.76
2004 Waltregny D, North B, Van Mellaert F, De Leval J, Verdin E, Castronovo V. Screening of histone deacetylases (HDAC) expression in human prostate cancer reveals distinct class I HDAC profiles between epithelial and stromal cells European Journal of Histochemistry. 48: 273-290. PMID 15590418  0.76
2004 Heltweg B, Dequiedt F, Marshall BL, Brauch C, Yoshida M, Nishino N, Verdin E, Jung M. Subtype selective substrates for histone deacetylases Journal of Medicinal Chemistry. 47: 5235-5243. PMID 15456267 DOI: 10.1021/jm0497592  0.76
2004 Williams SA, Chen LF, Kwon H, Fenard D, Bisgrove D, Verdin E, Greene WC. Prostratin antagonizes HIV latency by activating NF-kappaB. The Journal of Biological Chemistry. 279: 42008-17. PMID 15284245 DOI: 10.1074/jbc.M402124200  0.76
2004 Waltregny D, De Leval L, Glénisson W, Ly Tran S, North BJ, Bellahcène A, Weidle U, Verdin E, Castronovo V. Expression of histone deacetylase 8, a class I histone deacetylase, is restricted to cells showing smooth muscle differentiation in normal human tissues. The American Journal of Pathology. 165: 553-64. PMID 15277229 DOI: 10.1016/S0002-9440(10)63320-2  0.76
2004 Ott M, Dorr A, Hetzer-Egger C, Kaehlcke K, Schnolzer M, Henklein P, Cole P, Zhou MM, Verdin E. Tat acetylation: a regulatory switch between early and late phases in HIV transcription elongation. Novartis Foundation Symposium. 259: 182-93; discussion 1. PMID 15171254  0.76
2004 Verdin E, Dequiedt F, Kasler H, Olson, Mabadevan, Marks, Berger. HDAC7 regulates apoptosis in developing thymocytes Novartis Foundation Symposium. 259: 115-131. PMID 15171250  0.76
2004 North BJ, Verdin E. Sirtuins: Sir2-related NAD-dependent protein deacetylases. Genome Biology. 5: 224. PMID 15128440 DOI: 10.1186/gb-2004-5-5-224  0.76
2004 Verdin E, Dequiedt F, Fischle W, Frye R, Marshall B, North B. Measurement of Mammalian Histone Deacetylase Activity Methods in Enzymology. 377: 180-196. PMID 14979025 DOI: 10.1016/S0076-6879(03)77010-4  0.76
2003 Kaehlcke K, Dorr A, Hetzer-Egger C, Kiermer V, Henklein P, Schnoelzer M, Loret E, Cole PA, Verdin E, Ott M. Acetylation of Tat defines a cyclinT1-independent step in HIV transactivation. Molecular Cell. 12: 167-76. PMID 12887902 DOI: 10.1016/S1097-2765(03)00245-4  0.76
2003 Heltweg B, Dequiedt F, Verdin E, Jung M. Nonisotopic substrate for assaying both human zinc and NAD+-dependent histone deacetylases Analytical Biochemistry. 319: 42-48. PMID 12842105 DOI: 10.1016/S0003-2697(03)00276-8  0.76
2003 Dequiedt F, Kasler H, Fischle W, Kiermer V, Weinstein M, Herndier BG, Verdin E. HDAC7, a thymus-specific class II histone deacetylase, regulates Nur77 transcription and TCR-mediated apoptosis. Immunity. 18: 687-98. PMID 12753745 DOI: 10.1016/S1074-7613(03)00109-2  0.76
2003 Verdin E, Dequiedt F, Kasler HG. Class II histone deacetylases: versatile regulators. Trends in Genetics : Tig. 19: 286-93. PMID 12711221 DOI: 10.1016/S0168-9525(03)00073-8  0.76
2003 Jordan A, Bisgrove D, Verdin E. HIV reproducibly establishes a latent infection after acute infection of T cells in vitro Embo Journal. 22: 1868-1877. PMID 12682019 DOI: 10.1093/emboj/cdg188  0.76
2003 Pion M, Jordan A, Biancotto A, Dequiedt F, Gondois-Rey F, Rondeau S, Vigne R, Hejnar J, Verdin E, Hirsch I. Transcriptional suppression of in vitro-integrated human immunodeficiency virus type 1 does not correlate with proviral DNA methylation. Journal of Virology. 77: 4025-32. PMID 12634362 DOI: 10.1128/JVI.77.7.4025-4032.2003  0.76
2003 North BJ, Marshall BL, Borra MT, Denu JM, Verdin E. The human Sir2 ortholog, SIRT2, is an NAD+-dependent tubulin deacetylase. Molecular Cell. 11: 437-44. PMID 12620231 DOI: 10.1016/S1097-2765(03)00038-8  0.76
2002 Schwer B, North BJ, Frye RA, Ott M, Verdin E. The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase. The Journal of Cell Biology. 158: 647-57. PMID 12186850 DOI: 10.1083/jcb.200205057  0.76
2002 Dorr A, Kiermer V, Pedal A, Rackwitz HR, Henklein P, Schubert U, Zhou MM, Verdin E, Ott M. Transcriptional synergy between Tat and PCAF is dependent on the binding of acetylated Tat to the PCAF bromodomain. The Embo Journal. 21: 2715-23. PMID 12032084 DOI: 10.1093/emboj/21.11.2715  0.76
2002 Mujtaba S, He Y, Zeng L, Farooq A, Carlson JE, Ott M, Verdin E, Zhou MM. Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain. Molecular Cell. 9: 575-86. PMID 11931765 DOI: 10.1016/S1097-2765(02)00483-5  0.76
2002 Murphy JC, Fischle W, Verdin E, Sinclair JH. Control of cytomegalovirus lytic gene expression by histone acetylation Embo Journal. 21: 1112-1120. PMID 11867539 DOI: 10.1093/emboj/21.5.1112  0.76
2002 Deroanne CF, Bonjean K, Servotte S, Devy L, Colige A, Clausse N, Blacher S, Verdin E, Foidart JM, Nusgens BV, Castronovo V. Histone deacetylases inhibitors as anti-angiogenic agents altering vascular endothelial growth factor signaling Oncogene. 21: 427-436. PMID 11821955 DOI: 10.1038/sj/onc/1205108  0.76
2002 Borra MT, O'Neill FJ, Jackson MD, Marshall B, Verdin E, Foltz KR, Denu JM. Conserved enzymatic production and biological effect of O-acetyl-ADP-ribose by silent information regulator 2-like NAD+-dependent deacetylases. The Journal of Biological Chemistry. 277: 12632-41. PMID 11812793 DOI: 10.1074/jbc.M111830200  0.76
2002 Fischle W, Dequiedt F, Hendzel MJ, Guenther MG, Lazar MA, Voelter W, Verdin E. Enzymatic activity associated with class II HDACs is dependent on a multiprotein complex containing HDAC3 and SMRT/N-CoR. Molecular Cell. 9: 45-57. PMID 11804585 DOI: 10.1016/S1097-2765(01)00429-4  0.76
2001 Chen LF, Fischle W, Verdin E, Greene WC. Duration of nuclear NF-κB action regulated by reversible acetylation Science. 293: 1653-1657. PMID 11533489 DOI: 10.1126/science.1062374  0.76
2001 Kruhlak MJ, Hendzel MJ, Fischle W, Bertos NR, Hameed S, Yang XJ, Verdin E, Bazett-Jones DP. Regulation of Global Acetylation in Mitosis through Loss of Histone Acetyltransferases and Deacetylases from Chromatin Journal of Biological Chemistry. 276: 38307-38319. PMID 11479283 DOI: 10.1074/jbc.M100290200  0.76
2001 Fischle W, Kiermer V, Dequiedt F, Verdin E. The emerging role of class II histone deacetylases Biochemistry and Cell Biology. 79: 337-348. PMID 11467747 DOI: 10.1139/bcb-79-3-337  0.76
2001 Fischle W, Dequiedt F, Fillion M, Hendzel MJ, Voelter W, Verdin E. Human HDAC7 Histone Deacetylase Activity is Associated with HDAC3 in Vivo Journal of Biological Chemistry. 276: 35826-35835. PMID 11466315 DOI: 10.1074/jbc.M104935200  0.76
2001 Geenen V, Verdin E. Egg-cell complex, molecular embryology, human genome, then, human proteome | Complexe cellule-oeuf, embryologie moléculaire, génome humain, puis, protéome humain Revue MéDicale De LièGe. 56: 170. PMID 11338789  0.76
2001 Jordan A, Defechereux P, Verdin E. The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation Embo Journal. 20: 1726-1738. PMID 11285236 DOI: 10.1093/emboj/20.7.1726  0.76
2001 Thébault S, Verdin E, Lu J, McKinsey TA, Zhang CL, Olson NE. Regulation of skeletal myogenesis by association of the MEF2 transcription factor with class II histone deacetylases Chemtracts. 14: 720-726.  0.76
2001 Jordan A, Verdin E. Towards a molecular understanding of the silencing of transcription by heterochromatin: Methylation of histone H3 lysine 9 creates a binding site for HP1 protein. Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain - Role of histone H3 lysine 9 methylation in epigenetic control of heterochromatin assembly Chemtracts. 14: 582-588.  0.76
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