Michael Ewers - Publications

Affiliations: 
Ludwig Maximilian University Munich, München, Bayern, Germany 
Area:
Alzheimer's disease, MRI, biomarker, PET,

227 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Blömeke L, Rehn F, Pils M, Kraemer-Schulien V, Cousin A, Kutzsche J, Bujnicki T, Freiesleben SD, Schneider LS, Preis L, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, ... ... Ewers M, et al. Blood-based quantification of Aβ oligomers indicates impaired clearance from brain in ApoE ε4 positive subjects. Communications Medicine. 4: 262. PMID 39658587 DOI: 10.1038/s43856-024-00690-w  0.377
2024 Luan Y, Rubinski A, Biel D, Otero Svaldi D, Alonzo Higgins I, Shcherbinin S, Pontecorvo M, Franzmeier N, Ewers M. Tau-network mapping of domain-specific cognitive impairment in Alzheimer's disease. Neuroimage. Clinical. 44: 103699. PMID 39509992 DOI: 10.1016/j.nicl.2024.103699  0.376
2024 Vermunt L, Sutphen CL, Dicks E, de Leeuw DM, Allegri RF, Berman SB, Cash DM, Chhatwal JP, Cruchaga C, Day GS, Ewers M, Farlow MR, Fox NC, Ghetti B, Graff-Radford NR, et al. Axonal damage and inflammation response are biological correlates of decline in small-world values: a cohort study in autosomal dominant Alzheimer's disease. Brain Communications. 6: fcae357. PMID 39440304 DOI: 10.1093/braincomms/fcae357  0.325
2024 Wang X, Freiesleben SD, Schneider LS, Preis L, Priller J, Spruth EJ, Altenstein S, Schneider A, Fliessbach K, Wiltfang J, Hansen N, Jessen F, Rostamzadeh A, Duzel E, Glanz W, ... ... Ewers M, et al. Association of Neurogranin and BACE1 With Clinical Cognitive Decline in Individuals With Subjective Cognitive Decline. Neurology. 103: e209806. PMID 39303184 DOI: 10.1212/WNL.0000000000209806  0.392
2024 Lorenzini L, Maranzano A, Ingala S, Collij LE, Tranfa M, Blennow K, Di Perri C, Foley C, Fox NC, Frisoni GB, Haller S, Martinez-Lage P, Mollison D, O'Brien J, Payoux P, ... ... Ewers M, et al. Association of Vascular Risk Factors and Cerebrovascular Pathology With Alzheimer Disease Pathologic Changes in Individuals Without Dementia. Neurology. 103: e209801. PMID 39288341 DOI: 10.1212/WNL.0000000000209801  0.431
2024 Lorenzini L, Collij LE, Tesi N, Vilor-Tejedor N, Ingala S, Blennow K, Foley C, Frisoni GB, Haller S, Holstege H, van der van der Lee S, Martinez-Lage P, Marioni RE, McCartney DL, O' Brien J, ... ... Ewers M, et al. Alzheimer's disease genetic pathways impact cerebrospinal fluid biomarkers and imaging endophenotypes in non-demented individuals. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 39073684 DOI: 10.1002/alz.14096  0.357
2024 Shao K, Hu X, Kleineidam L, Stark M, Altenstein S, Amthauer H, Boecker H, Buchert R, Buerger K, Butryn M, Cai Y, Cai Y, Cosma NC, Chen G, Chen Z, ... ... Ewers M, et al. Amyloid and SCD jointly predict cognitive decline across Chinese and German cohorts. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 39072956 DOI: 10.1002/alz.14119  0.43
2024 Arenaza-Urquijo EM, Boyle R, Casaletto K, Anstey KJ, Vila-Castelar C, Colverson A, Palpatzis E, Eissman JM, Kheng Siang Ng T, Raghavan S, Akinci M, Vonk JMJ, Machado LS, Zanwar PP, Shrestha HL, ... ... Ewers M, et al. Sex and gender differences in cognitive resilience to aging and Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38967222 DOI: 10.1002/alz.13844  0.378
2024 Vogelgsang J, Hansen N, Stark M, Wagner M, Klafki H, Morgado BM, Jahn-Brodmann A, Schott B, Esselmann H, Bauer C, Schuchhardt J, Kleineidam L, Wolfsgruber S, Peters O, Schneider LS, ... ... Ewers M, et al. Plasma amyloid beta X-42/X-40 ratio and cognitive decline in suspected early and preclinical Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 38940303 DOI: 10.1002/alz.13909  0.321
2024 Tranfa M, Lorenzini L, Collij LE, Vállez García D, Ingala S, Pontillo G, Pieperhoff L, Maranzano A, Wolz R, Haller S, Blennow K, Frisoni G, Sudre CH, Chételat G, Ewers M, et al. Alzheimer's Disease and Small Vessel Disease Differentially Affect White Matter Microstructure. Annals of Clinical and Translational Neurology. PMID 38757392 DOI: 10.1002/acn3.52071  0.395
2024 Dörner M, Seebach K, Heneka MT, Menze I, von Känel R, Euler S, Schreiber F, Arndt P, Neumann K, Hildebrand A, John AC, Tyndall A, Kirchebner J, Tacik P, Jansen R, ... ... Ewers M, et al. Inferior Frontal Sulcal Hyperintensities on Brain MRI Are Associated with Amyloid Positivity beyond Age-Results from the Multicentre Observational DELCODE Study. Diagnostics (Basel, Switzerland). 14. PMID 38732354 DOI: 10.3390/diagnostics14090940  0.382
2024 Blömeke L, Rehn F, Kraemer-Schulien V, Kutzsche J, Pils M, Bujnicki T, Lewczuk P, Kornhuber J, Freiesleben SD, Schneider LS, Preis L, Priller J, Spruth EJ, Altenstein S, Lohse A, ... ... Ewers M, et al. Aβ oligomers peak in early stages of Alzheimer's disease preceding tau pathology. Alzheimer's & Dementia (Amsterdam, Netherlands). 16: e12589. PMID 38666085 DOI: 10.1002/dad2.12589  0.41
2024 Baumeister H, Vogel JW, Insel PS, Kleineidam L, Wolfsgruber S, Stark M, Gellersen HM, Yakupov R, Schmid MC, Lüsebrink F, Brosseron F, Ziegler G, Freiesleben SD, Preis L, Schneider LS, ... ... Ewers M, et al. A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings. Brain : a Journal of Neurology. PMID 38654513 DOI: 10.1093/brain/awae118  0.414
2024 Deike K, Decker A, Scheyhing P, Harten J, Zimmermann N, Paech D, Peters O, Freiesleben SD, Schneider LS, Preis L, Priller J, Spruth E, Altenstein S, Lohse A, Fliessbach K, ... ... Ewers M, et al. Machine Learning-Based Perivascular Space Volumetry in Alzheimer Disease. Investigative Radiology. PMID 38652067 DOI: 10.1097/RLI.0000000000001077  0.435
2024 Hayek D, Ziegler G, Kleineidam L, Brosseron F, Nemali A, Vockert N, Ravichandran KA, Betts MJ, Peters O, Schneider LS, Wang X, Priller J, Altenstein S, Schneider A, Fliessbach K, ... ... Ewers M, et al. Different inflammatory signatures based on CSF biomarkers relate to preserved or diminished brain structure and cognition. Molecular Psychiatry. PMID 38216727 DOI: 10.1038/s41380-023-02387-3  0.408
2024 Franzmeier N, Dehsarvi A, Steward A, Biel D, Dewenter A, Roemer SN, Wagner F, Groß M, Brendel M, Moscoso A, Arunachalam P, Blennow K, Zetterberg H, Ewers M, Schöll M. Elevated CSF GAP-43 is associated with accelerated tau accumulation and spread in Alzheimer's disease. Nature Communications. 15: 202. PMID 38172114 DOI: 10.1038/s41467-023-44374-w  0.352
2023 Rubinski A, Dewenter A, Zheng L, Franzmeier N, Stephenson H, Deming Y, Duering M, Gesierich B, Denecke J, Pham AV, Bendlin B, Ewers M. Florbetapir PET-assessed demyelination is associated with faster tau accumulation in an APOE ε4-dependent manner. European Journal of Nuclear Medicine and Molecular Imaging. PMID 38049659 DOI: 10.1007/s00259-023-06530-8  0.7
2023 Steward A, Biel D, Dewenter A, Roemer S, Wagner F, Dehsarvi A, Rathore S, Otero Svaldi D, Higgins I, Brendel M, Dichgans M, Shcherbinin S, Ewers M, Franzmeier N. ApoE4 and Connectivity-Mediated Spreading of Tau Pathology at Lower Amyloid Levels. Jama Neurology. PMID 37930695 DOI: 10.1001/jamaneurol.2023.4038  0.424
2023 Teipel SJ, Dyrba M, Levin F, Altenstein S, Berger M, Beyle A, Brosseron F, Buerger K, Burow L, Dobisch L, Ewers M, Fliessbach K, Frommann I, Glanz W, Goerss D, et al. Cognitive Trajectories in Preclinical and Prodromal Alzheimer's Disease Related to Amyloid Status and Brain Atrophy: A Bayesian Approach. Journal of Alzheimer's Disease Reports. 7: 1055-1076. PMID 37849637 DOI: 10.3233/ADR-230027  0.448
2023 Zheng L, Rubinski A, Denecke J, Luan Y, Smith R, Strandberg O, Stomrud E, Ossenkoppele R, Svaldi DO, Higgins IA, Shcherbinin S, Pontecorvo MJ, Hansson O, Franzmeier N, Ewers M. Combined Connectomics, MAPT Gene Expression, and Amyloid Deposition to Explain Regional Tau Deposition in Alzheimer Disease. Annals of Neurology. PMID 37837382 DOI: 10.1002/ana.26818  0.319
2023 Stark M, Wolfsgruber S, Kleineidam L, Frommann I, Altenstein S, Bartels C, Brosseron F, Buerger K, Burow L, Butryn M, Ewers M, Fliessbach K, Gabelin T, Glanz W, Goerss D, et al. Relevance of Minor Neuropsychological Deficits in Patients With Subjective Cognitive Decline. Neurology. PMID 37821235 DOI: 10.1212/WNL.0000000000207844  0.366
2023 Waschkies KF, Soch J, Darna M, Richter A, Altenstein S, Beyle A, Brosseron F, Buchholz F, Butryn M, Dobisch L, Ewers M, Fliessbach K, Gabelin T, Glanz W, Goerss D, et al. Machine learning-based classification of Alzheimer's disease and its at-risk states using personality traits, anxiety, and depression. International Journal of Geriatric Psychiatry. 38: e6007. PMID 37800601 DOI: 10.1002/gps.6007  0.404
2023 Daamen M, Scheef L, Li S, Grothe MJ, Gaertner FC, Buchert R, Buerger K, Dobisch L, Drzezga A, Essler M, Ewers M, Fliessbach K, Herrera Melendez AL, Hetzer S, Janowitz D, et al. Cortical Amyloid Burden Relates to Basal Forebrain Volume in Subjective Cognitive Decline. Journal of Alzheimer's Disease : Jad. PMID 37638433 DOI: 10.3233/JAD-230141  0.415
2023 Bernal J, Schreiber S, Menze I, Ostendorf A, Pfister M, Geisendörfer J, Nemali A, Maass A, Yakupov R, Peters O, Preis L, Schneider L, Herrera AL, Priller J, Spruth EJ, ... ... Ewers M, et al. Arterial hypertension and β-amyloid accumulation have spatially overlapping effects on posterior white matter hyperintensity volume: a cross-sectional study. Alzheimer's Research & Therapy. 15: 97. PMID 37226207 DOI: 10.1186/s13195-023-01243-4  0.343
2023 Lorenzini L, Ingala S, Collij LE, Wottschel V, Haller S, Blennow K, Frisoni G, Chételat G, Payoux P, Lage-Martinez P, Ewers M, Waldman A, Wardlaw J, Ritchie C, Gispert JD, et al. Eigenvector centrality dynamics are related to Alzheimer's disease pathological changes in non-demented individuals. Brain Communications. 5: fcad088. PMID 37151225 DOI: 10.1093/braincomms/fcad088  0.351
2023 Yildirim Z, Delen F, Berron D, Baumeister H, Ziegler G, Schütze H, Glanz W, Dobisch L, Peters O, Freiesleben SD, Schneider LS, Priller J, Spruth EJ, Schneider A, Fliessbach K, ... ... Ewers M, et al. Brain reserve contributes to distinguishing preclinical Alzheimer's stages 1 and 2. Alzheimer's Research & Therapy. 15: 43. PMID 36855049 DOI: 10.1186/s13195-023-01187-9  0.313
2023 Gaubert M, Dell'Orco A, Lange C, Garnier-Crussard A, Zimmermann I, Dyrba M, Duering M, Ziegler G, Peters O, Preis L, Priller J, Spruth EJ, Schneider A, Fliessbach K, Wiltfang J, ... ... Ewers M, et al. Performance evaluation of automated white matter hyperintensity segmentation algorithms in a multicenter cohort on cognitive impairment and dementia. Frontiers in Psychiatry. 13: 1010273. PMID 36713907 DOI: 10.3389/fpsyt.2022.1010273  0.364
2023 Brosseron F, Maass A, Kleineidam L, Ravichandran KA, Kolbe CC, Wolfsgruber S, Santarelli F, Häsler LM, McManus R, Ising C, Röske S, Peters O, Cosma NC, Schneider LS, Wang X, ... ... Ewers M, et al. Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer's disease: results from the DELCODE study. Alzheimer's Research & Therapy. 15: 13. PMID 36631909 DOI: 10.1186/s13195-022-01118-0  0.396
2023 Biel D, Suárez-Calvet M, Hager P, Rubinski A, Dewenter A, Steward A, Roemer S, Ewers M, Haass C, Brendel M, Franzmeier N. sTREM2 is associated with amyloid-related p-tau increases and glucose hypermetabolism in Alzheimer's disease. Embo Molecular Medicine. e16987. PMID 36620941 DOI: 10.15252/emmm.202216987  0.408
2022 Rubinski A, Frerich S, Malik R, Franzmeier N, Ramirez A, Dichgans M, Ewers M. Polygenic Effect on Tau Pathology Progression in Alzheimer's Disease. Annals of Neurology. PMID 36571564 DOI: 10.1002/ana.26588  0.414
2022 Kleineidam L, Wolfsgruber S, Weyrauch AS, Zulka LE, Forstmeier S, Roeske S, van den Bussche H, Kaduszkiewicz H, Wiese B, Weyerer S, Werle J, Fuchs A, Pentzek M, Brettschneider C, König HH, ... ... Ewers M, et al. Midlife occupational cognitive requirements protect cognitive function in old age by increasing cognitive reserve. Frontiers in Psychology. 13: 957308. PMID 36571008 DOI: 10.3389/fpsyg.2022.957308  0.322
2022 Ersoezlue E, Rauchmann BS, Schneider-Axmann T, Wagner M, Ballarini T, Tato M, Utecht J, Kurz C, Papazov B, Guersel S, Burow L, Koller G, Stöcklein S, Keeser D, Bartels C, ... ... Ewers M, et al. Lifelong experiences as a proxy of cognitive reserve moderate the association between connectivity and cognition in Alzheimer's disease. Neurobiology of Aging. 122: 33-44. PMID 36476760 DOI: 10.1016/j.neurobiolaging.2022.05.015  0.448
2022 Steward A, Biel D, Brendel M, Dewenter A, Roemer S, Rubinski A, Luan Y, Dichgans M, Ewers M, Franzmeier N. Functional network segregation is associated with attenuated tau spreading in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 36433865 DOI: 10.1002/alz.12867  0.404
2022 Biel D, Luan Y, Brendel M, Hager P, Dewenter A, Moscoso A, Otero Svaldi D, Higgins IA, Pontecorvo M, Römer S, Steward A, Rubinski A, Zheng L, Schöll M, Shcherbinin S, ... Ewers M, et al. Combining tau-PET and fMRI meta-analyses for patient-centered prediction of cognitive decline in Alzheimer's disease. Alzheimer's Research & Therapy. 14: 166. PMID 36345046 DOI: 10.1186/s13195-022-01105-5  0.347
2022 Pichet Binette A, Franzmeier N, Spotorno N, Ewers M, Brendel M, Biel D, Strandberg O, Janelidze S, Palmqvist S, Mattsson-Carlgren N, Smith R, Stomrud E, Ossenkoppele R, Hansson O. Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer's disease. Nature Communications. 13: 6635. PMID 36333294 DOI: 10.1038/s41467-022-34129-4  0.413
2022 Nemy M, Dyrba M, Brosseron F, Buerger K, Dechent P, Dobisch L, Ewers M, Fliessbach K, Glanz W, Goerss D, Heneka MT, Hetzer S, Incesoy EI, Janowitz D, Kilimann I, et al. Cholinergic white matter pathways along the Alzheimer's disease continuum. Brain : a Journal of Neurology. PMID 36288546 DOI: 10.1093/brain/awac385  0.405
2022 Rubinski A, Franzmeier N, Dewenter A, Luan Y, Smith R, Strandberg O, Ossenkoppele R, Dichgans M, Hansson O, Ewers M. Higher levels of myelin are associated with higher resistance against tau pathology in Alzheimer's disease. Alzheimer's Research & Therapy. 14: 139. PMID 36153607 DOI: 10.1186/s13195-022-01074-9  0.384
2022 Rauchmann BS, Brendel M, Franzmeier N, Trappmann L, Zaganjori M, Ersoezlue E, Morenas-Rodriguez E, Guersel S, Burow L, Kurz C, Haeckert J, Tatò M, Utecht J, Papazov B, Pogarell O, ... ... Ewers M, et al. Microglial Activation and Connectivity in Alzheimer Disease and Aging. Annals of Neurology. PMID 36053756 DOI: 10.1002/ana.26465  0.377
2022 Frontzkowski L, Ewers M, Brendel M, Biel D, Ossenkoppele R, Hager P, Steward A, Dewenter A, Römer S, Rubinski A, Buerger K, Janowitz D, Binette AP, Smith R, Strandberg O, et al. Earlier Alzheimer's disease onset is associated with tau pathology in brain hub regions and facilitated tau spreading. Nature Communications. 13: 4899. PMID 35987901 DOI: 10.1038/s41467-022-32592-7  0.455
2022 Dewenter A, Jacob MA, Cai M, Gesierich B, Hager P, Kopczak A, Biel D, Ewers M, Tuladhar AM, de Leeuw FE, Dichgans M, Franzmeier N, Duering M. Disentangling the effects of Alzheimer's and small vessel disease on white matter fibre tracts. Brain : a Journal of Neurology. PMID 35859352 DOI: 10.1093/brain/awac265  0.339
2022 Ali M, Sung YJ, Wang F, Fernández MV, Morris JC, Fagan AM, Blennow K, Zetterberg H, Heslegrave A, Johansson PM, Svensson J, Nellgård B, Lleó A, Alcolea D, Clarimon J, ... ... Ewers M, et al. Leveraging large multi-center cohorts of Alzheimer disease endophenotypes to understand the role of Klotho heterozygosity on disease risk. Plos One. 17: e0267298. PMID 35617280 DOI: 10.1371/journal.pone.0267298  0.435
2022 Jessen F, Wolfsgruber S, Kleineindam L, Spottke A, Altenstein S, Bartels C, Berger M, Brosseron F, Daamen M, Dichgans M, Dobisch L, Ewers M, Fenski F, Fliessbach K, Freiesleben SD, et al. Subjective cognitive decline and stage 2 of Alzheimer disease in patients from memory centers. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 35451563 DOI: 10.1002/alz.12674  0.406
2022 Bellenguez C, Küçükali F, Jansen IE, Kleineidam L, Moreno-Grau S, Amin N, Naj AC, Campos-Martin R, Grenier-Boley B, Andrade V, Holmans PA, Boland A, Damotte V, van der Lee SJ, Costa MR, ... ... Ewers M, et al. New insights into the genetic etiology of Alzheimer's disease and related dementias. Nature Genetics. PMID 35379992 DOI: 10.1038/s41588-022-01024-z  0.396
2022 Morenas-Rodríguez E, Li Y, Nuscher B, Franzmeier N, Xiong C, Suárez-Calvet M, Fagan AM, Schultz S, Gordon BA, Benzinger TLS, Hassenstab J, McDade E, Feederle R, Karch CM, Schlepckow K, ... ... Ewers M, et al. Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study. The Lancet. Neurology. 21: 329-341. PMID 35305339 DOI: 10.1016/S1474-4422(22)00027-8  0.46
2021 Brosseron F, Maass A, Kleineidam L, Ravichandran KA, González PG, McManus RM, Ising C, Santarelli F, Kolbe CC, Häsler LM, Wolfsgruber S, Marquié M, Boada M, Orellana A, de Rojas I, ... ... Ewers M, et al. Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer's disease. Neuron. PMID 34995486 DOI: 10.1016/j.neuron.2021.12.016  0.441
2021 Teipel SJ, Dyrba M, Ballarini T, Brosseron F, Bruno D, Buerger K, Cosma NC, Dechent P, Dobisch L, Düzel E, Ewers M, Fliessbach K, Haynes JD, Janowitz D, Kilimann I, et al. Association of Cholinergic Basal Forebrain Volume and Functional Connectivity with Markers of Inflammatory Response in the Alzheimer's Disease Spectrum. Journal of Alzheimer's Disease : Jad. PMID 34924387 DOI: 10.3233/JAD-215196  0.39
2021 Neitzel J, Franzmeier N, Rubinski A, Dichgans M, Brendel M, Malik R, Ewers M. KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer's disease. Nature Communications. 12: 3825. PMID 34158479 DOI: 10.1038/s41467-021-23755-z  0.427
2021 de Rojas I, Moreno-Grau S, Tesi N, Grenier-Boley B, Andrade V, Jansen IE, Pedersen NL, Stringa N, Zettergren A, Hernández I, Montrreal L, Antúnez C, Antonell A, Tankard RM, Bis JC, ... ... Ewers M, et al. Common variants in Alzheimer's disease and risk stratification by polygenic risk scores. Nature Communications. 12: 3417. PMID 34099642 DOI: 10.1038/s41467-021-22491-8  0.31
2021 Franzmeier N, Ossenkoppele R, Brendel M, Rubinski A, Smith R, Kumar A, Mattsson-Carlgren N, Strandberg O, Duering M, Buerger K, Dichgans M, Hansson O, Ewers M. The BIN1 rs744373 Alzheimer's disease risk SNP is associated with faster Aβ-associated tau accumulation and cognitive decline. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 34060233 DOI: 10.1002/alz.12371  0.357
2021 Ingala S, De Boer C, Masselink LA, Vergari I, Lorenzini L, Blennow K, Chételat G, Di Perri C, Ewers M, van der Flier WM, Fox NC, Gispert JD, Haller S, Molinuevo JL, Muniz-Terrera G, et al. Application of the ATN classification scheme in a population without dementia: Findings from the EPAD cohort. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33811742 DOI: 10.1002/alz.12292  0.301
2021 Rubinski A, Tosun D, Franzmeier N, Neitzel J, Frontzkowski L, Weiner M, Ewers M. Lower cerebral perfusion is associated with tau-PET in the entorhinal cortex across the Alzheimer's continuum. Neurobiology of Aging. 102: 111-118. PMID 33765424 DOI: 10.1016/j.neurobiolaging.2021.02.003  0.408
2021 Ewers M, Luan Y, Frontzkowski L, Neitzel J, Rubinski A, Dichgans M, Hassenstab J, Gordon BA, Chhatwal JP, Levin J, Schofield P, Benzinger TLS, Morris JC, Goate A, Karch CM, et al. Segregation of functional networks is associated with cognitive resilience in Alzheimer's disease. Brain : a Journal of Neurology. PMID 33725114 DOI: 10.1093/brain/awab112  0.439
2020 Biechele G, Wind K, Blume T, Sacher C, Beyer L, Eckenweber F, Franzmeier N, Ewers M, Zott B, Lindner S, Gildehaus FJ, von Ungern-Sternberg B, Tahirovic S, Willem M, Bartenstein P, et al. Microglial Activation in the Right Amygdala-Entorhinal-Hippocampal Complex is Associated with Preserved Spatial Learning in App mice. Neuroimage. 117707. PMID 33385560 DOI: 10.1016/j.neuroimage.2020.117707  0.306
2020 Franzmeier N, Dewenter A, Frontzkowski L, Dichgans M, Rubinski A, Neitzel J, Smith R, Strandberg O, Ossenkoppele R, Buerger K, Duering M, Hansson O, Ewers M. Patient-centered connectivity-based prediction of tau pathology spread in Alzheimer's disease. Science Advances. 6. PMID 33246962 DOI: 10.1126/sciadv.abd1327  0.344
2020 Bartrés-Faz D, Arenaza-Urquijo E, Ewers M, Belleville S, Chételat G, Franzmeier N, Gonneaud J, de Echevarri JMG, Okonkwo O, Schultz S, Valenzuela M, Stern Y, Vemuri P. Theoretical frameworks and approaches used within the Reserve, Resilience and Protective Factors professional interest area of the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12115. PMID 33204812 DOI: 10.1002/dad2.12115  0.304
2020 Rubinski A, Franzmeier N, Neitzel J, Ewers M. FDG-PET hypermetabolism is associated with higher tau-PET in mild cognitive impairment at low amyloid-PET levels. Alzheimer's Research & Therapy. 12: 133. PMID 33076977 DOI: 10.1186/s13195-020-00702-6  0.377
2020 Franzmeier N, Suárez-Calvet M, Frontzkowski L, Moore A, Hohman TJ, Morenas-Rodriguez E, Nuscher B, Shaw L, Trojanowski JQ, Dichgans M, Kleinberger G, Haass C, Ewers M. Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration. Molecular Neurodegeneration. 15: 57. PMID 33032659 DOI: 10.1186/s13024-020-00407-2  0.387
2020 Finsterwalder S, Vlegels N, Gesierich B, Araque Caballero MÁ, Weaver NA, Franzmeier N, Georgakis MK, Konieczny MJ, Koek HL, Karch CM, Graff-Radford NR, Salloway S, Oh H, Allegri RF, Chhatwal JP, ... ... Ewers M, et al. Small vessel disease more than Alzheimer's disease determines diffusion MRI alterations in memory clinic patients. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32808747 DOI: 10.1002/Alz.12150  0.447
2020 Ewers M, Biechele G, Suárez-Calvet M, Sacher C, Blume T, Morenas-Rodriguez E, Deming Y, Piccio L, Cruchaga C, Kleinberger G, Shaw L, Trojanowski JQ, Herms J, Dichgans M, et al. Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation. Embo Molecular Medicine. e12308. PMID 32790063 DOI: 10.15252/Emmm.202012308  0.713
2020 Schultz SA, Strain JF, Adedokun A, Wang Q, Preische O, Kuhle J, Flores S, Keefe S, Dincer A, Ances BM, Berman SB, Brickman AM, Cash DM, Chhatwal J, Cruchaga C, ... Ewers M, et al. Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease. Neurobiology of Disease. 104960. PMID 32522711 DOI: 10.1016/J.Nbd.2020.104960  0.371
2020 Caballero MÁA, Song Z, Rubinski A, Duering M, Dichgans M, Park DC, Ewers M. Age-dependent amyloid deposition is associated with white matter alterations in cognitively normal adults during the adult life span. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32147939 DOI: 10.1002/Alz.12062  0.475
2020 Gesierich B, Tuladhar AM, Ter Telgte A, Wiegertjes K, Konieczny MJ, Finsterwalder S, Hübner M, Pirpamer L, Koini M, Abdulkadir A, Franzmeier N, Norris DG, Marques JP, Zu Eulenburg P, Ewers M, et al. Alterations and test-retest reliability of functional connectivity network measures in cerebral small vessel disease. Human Brain Mapping. PMID 32087047 DOI: 10.1002/Hbm.24967  0.347
2020 Franzmeier N, Koutsouleris N, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, Duering M, Dichgans M, Levin J, Gordon BA, Lim YY, Masters CL, Rossor M, Fox NC, ... ... Ewers M, et al. Predicting sporadic Alzheimer's disease progression via inherited Alzheimer's disease-informed machine-learning. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 32043733 DOI: 10.1002/Alz.12032  0.497
2020 Franzmeier N, Neitzel J, Rubinski A, Smith R, Strandberg O, Ossenkoppele R, Hansson O, Ewers M. Functional brain architecture is associated with the rate of tau accumulation in Alzheimer's disease. Nature Communications. 11: 347. PMID 31953405 DOI: 10.1038/s41467-019-14159-1  0.434
2019 Ewers M. Reserve in Alzheimer's disease: update on the concept, functional mechanisms and sex differences. Current Opinion in Psychiatry. PMID 31789678 DOI: 10.1097/Yco.0000000000000574  0.41
2019 Ewers M, Franzmeier N, Suárez-Calvet M, Morenas-Rodriguez E, Caballero MAA, Kleinberger G, Piccio L, Cruchaga C, Deming Y, Dichgans M, Trojanowski JQ, Shaw LM, Weiner MW, Haass C. Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease. Science Translational Medicine. 11. PMID 31462511 DOI: 10.1126/Scitranslmed.Aav6221  0.758
2019 Deming Y, Filipello F, Cignarella F, Cantoni C, Hsu S, Mikesell R, Li Z, Del-Aguila JL, Dube U, Farias FG, Bradley J, Budde J, Ibanez L, Fernandez MV, Blennow K, ... ... Ewers M, et al. The gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk. Science Translational Medicine. 11. PMID 31413141 DOI: 10.1126/Scitranslmed.Aau2291  0.717
2019 Beyer L, Schnabel J, Kazmierczak P, Ewers M, Schönecker S, Prix C, Meyer-Wilmes J, Unterrainer M, Catak C, Pogarell O, Perneczky R, Albert NL, Bartenstein P, Danek A, Buerger K, et al. Neuronal injury biomarkers for assessment of the individual cognitive reserve in clinically suspected Alzheimer's disease. Neuroimage. Clinical. 24: 101949. PMID 31398553 DOI: 10.1016/j.nicl.2019.101949  0.37
2019 Bischof GN, Ewers M, Franzmeier N, Grothe MJ, Hoenig M, Kocagoncu E, Neitzel J, Rowe JB, Strafella A, Drzezga A, van Eimeren T. Connectomics and molecular imaging in neurodegeneration. European Journal of Nuclear Medicine and Molecular Imaging. PMID 31292699 DOI: 10.1007/S00259-019-04394-5  0.308
2019 Neitzel J, Franzmeier N, Rubinski A, Ewers M. Left frontal connectivity attenuates the adverse effect of entorhinal tau pathology on memory. Neurology. 93: e347-e357. PMID 31235661 DOI: 10.1212/Wnl.0000000000007822  0.36
2019 Sun Y, Wang X, Wang Y, Dong H, Lu J, Scheininger T, Ewers M, Jessen F, Zuo XN, Han Y. Anxiety correlates with cortical surface area in subjective cognitive decline: APOE ε4 carriers versus APOE ε4 non-carriers. Alzheimer's Research & Therapy. 11: 50. PMID 31159873 DOI: 10.1186/S13195-019-0505-0  0.452
2019 Franzmeier N, Rubinski A, Neitzel J, Ewers M. The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory. Nature Communications. 10: 1766. PMID 30992433 DOI: 10.1038/S41467-019-09564-5  0.402
2019 Franzmeier N, Ren J, Damm A, Monté-Rubio G, Boada M, Ruiz A, Ramirez A, Jessen F, Düzel E, Rodríguez Gómez O, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, ... ... Ewers M, et al. The BDNF SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease. Molecular Psychiatry. PMID 30899092 DOI: 10.1038/S41380-019-0404-6  0.522
2019 Perneczky R, Kempermann G, Korczyn AD, Matthews FE, Ikram MA, Scarmeas N, Chetelat G, Stern Y, Ewers M. Translational research on reserve against neurodegenerative disease: consensus report of the International Conference on Cognitive Reserve in the Dementias and the Alzheimer's Association Reserve, Resilience and Protective Factors Professional Interest Area working groups. Bmc Medicine. 17: 47. PMID 30808345 DOI: 10.1186/S12916-019-1283-Z  0.408
2019 Franzmeier N, Rubinski A, Neitzel J, Kim Y, Damm A, Na DL, Kim HJ, Lyoo CH, Cho H, Finsterwalder S, Duering M, Seo SW, Ewers M. Functional connectivity associated with tau levels in ageing, Alzheimer's, and small vessel disease. Brain : a Journal of Neurology. PMID 30770704 DOI: 10.1093/Brain/Awz026  0.524
2019 Suárez-Calvet M, Morenas-Rodríguez E, Kleinberger G, Schlepckow K, Caballero MÁA, Franzmeier N, Capell A, Fellerer K, Nuscher B, Eren E, Levin J, Deming Y, Piccio L, Karch CM, Cruchaga C, ... ... Ewers M, et al. Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid-β pathology. Molecular Neurodegeneration. 14: 1. PMID 30630532 DOI: 10.1186/S13024-018-0301-5  0.732
2019 Ewers M, Franzmeier N, Suárez-Calvet M, Morenas E, Piccio L, Cruchaga C, Robles Y, Trojanowski JQ, Shaw LM, Weiner MW, Haass C. O3-12-05: Increased Csf Soluble Trem2 Is Associated With Ameliorated Longitudinal Cognitive And Clinical Decline In Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4694  0.48
2019 Franzmeier N, Neitzel J, Rubinski A, Ewers M, Initiative ADN. Ic-P-026: Functional Brain Architecture Predicts Longitudinal Tau Spreading In Alzheimer'S Disease Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.4188  0.424
2019 Wolfsgruber S, Kleineidam L, Peters O, Buerger K, Ewers M, Priller J, Laske C, Teipel SJ, Schneider A, Spottke A, Heneka MT, Wiltfang J, Jessen F, Wagner M. P3-447: Minor Neuropsychological Deficits In Cognitively Normal Older Individuals With Subjective Cognitive Decline: Results From The Delcode Study Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3481  0.364
2019 Rubinski A, Franzmeier N, Neitzel J, Ewers M. P3-327: Tau Pathology Is Associated With Perfusion Deficits In The Entorhinal Cortex In Non-Demented Subjects Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.3359  0.364
2019 Neitzel J, Franzmeier N, Rubinski A, Ewers M. P2-357: Structural And Functional Connectivity Modulate The Association Between The Rate Of Regional Amyloid-Pet Change And Tau-Pet Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2764  0.347
2019 Franzmeier N, Rubinski A, Neitzel J, Ewers M, Initiative ADN. Ic-P-053: The Bin1 Rs744373 Snp Is A Risk Factor For Developing Tau Pathology Independent Of Amyloid Alzheimers & Dementia. 15. DOI: 10.1016/J.Jalz.2019.06.2546  0.317
2018 Babulal GM, Quiroz YT, Albensi BC, Arenaza-Urquijo E, Astell AJ, Babiloni C, Bahar-Fuchs A, Bell J, Bowman GL, Brickman AM, Chételat G, Ciro C, Cohen AD, Dilworth-Anderson P, Dodge HH, ... ... Ewers M, et al. Perspectives on ethnic and racial disparities in Alzheimer's disease and related dementias: Update and areas of immediate need. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30555031 DOI: 10.1016/J.Jalz.2018.09.009  0.424
2018 Suárez-Calvet M, Capell A, Araque Caballero MÁ, Morenas-Rodríguez E, Fellerer K, Franzmeier N, Kleinberger G, Eren E, Deming Y, Piccio L, Karch CM, Cruchaga C, Paumier K, Bateman RJ, Fagan AM, ... ... Ewers M, et al. CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline. Embo Molecular Medicine. PMID 30482868 DOI: 10.15252/Emmm.201809712  0.763
2018 Ten Kate M, Ingala S, Schwarz AJ, Fox NC, Chételat G, van Berckel BNM, Ewers M, Foley C, Gispert JD, Hill D, Irizarry MC, Lammertsma AA, Molinuevo JL, Ritchie C, Scheltens P, et al. Secondary prevention of Alzheimer's dementia: neuroimaging contributions. Alzheimer's Research & Therapy. 10: 112. PMID 30376881 DOI: 10.1186/S13195-018-0438-Z  0.467
2018 Jung NY, Cho H, Kim YJ, Kim HJ, Lee JM, Park S, Kim ST, Kim EJ, Kim JS, Moon SH, Lee JH, Ewers M, Na DL, Seo SW. The impact of education on cortical thickness in amyloid-negative subcortical vascular dementia: cognitive reserve hypothesis. Alzheimer's Research & Therapy. 10: 103. PMID 30261914 DOI: 10.1186/S13195-018-0432-5  0.432
2018 Araque Caballero MÁ, Suárez-Calvet M, Duering M, Franzmeier N, Benzinger T, Fagan AM, Bateman RJ, Jack CR, Levin J, Dichgans M, Jucker M, Karch C, Masters CL, Morris JC, Weiner M, ... ... Ewers M, et al. White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer's disease. Brain : a Journal of Neurology. PMID 30239611 DOI: 10.1093/Brain/Awy229  0.436
2018 Stern Y, Arenaza-Urquijo EM, Bartrés-Faz D, Belleville S, Cantilon M, Chetelat G, Ewers M, Franzmeier N, Kempermann G, Kremen WS, Okonkwo O, Scarmeas N, Soldan A, Udeh-Momoh C, Valenzuela M, et al. Whitepaper: Defining and investigating cognitive reserve, brain reserve, and brain maintenance. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30222945 DOI: 10.1016/J.Jalz.2018.07.219  0.345
2018 Kim Y, Jang H, Joo Kim S, Hyun Cho S, Eun Kim S, Kim ST, Jin Kim H, Hwan Moon S, Ewers M, Im K, Kwon H, Na LD, Won Seo S. Vascular Effects on Depressive Symptoms in Cognitive Impairment. Journal of Alzheimer's Disease : Jad. PMID 30056427 DOI: 10.3233/Jad-180394  0.419
2018 Duering M, Konieczny MJ, Tiedt S, Baykara E, Tuladhar AM, Leijsen EV, Lyrer P, Engelter ST, Gesierich B, Achmüller M, Barro C, Adam R, Ewers M, Dichgans M, Kuhle J, et al. Serum Neurofilament Light Chain Levels Are Related to Small Vessel Disease Burden. Journal of Stroke. 20: 228-238. PMID 29886723 DOI: 10.5853/Jos.2017.02565  0.335
2018 Franzmeier N, Düzel E, Jessen F, Buerger K, Levin J, Duering M, Dichgans M, Haass C, Suárez-Calvet M, Fagan AM, Paumier K, Benzinger T, Masters CL, Morris JC, Perneczky R, ... ... Ewers M, et al. Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease. Brain : a Journal of Neurology. PMID 29462334 DOI: 10.1093/Brain/Awy008  0.531
2018 Duering M, Finsterwalder S, Baykara E, Tuladhar AM, Gesierich B, Konieczny MJ, Malik R, Franzmeier N, Ewers M, Jouvent E, Biessels GJ, Schmidt R, de Leeuw FE, Pasternak O, Dichgans M. Free water determines diffusion alterations and clinical status in cerebral small vessel disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 29406155 DOI: 10.1016/J.Jalz.2017.12.007  0.355
2018 Caballero MAA, Park DC, Song Z, Levin J, Bateman RJ, Morris JC, Jucker M, Danek A, Yakushev I, Benzinger TLS, Ewers M, Dian. O4-04-05: Fiber-Tract-Specific Decline In White-Matter Integrity During The Adult Lifespan And Preclinical Alzheimer'S Disease: Results From The Dallas Lifespan Brain Study And Dian Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2931  0.372
2018 Miebach L, Wolfsgruber S, Frommann I, Roeske S, Oliver P, Buerger K, Nestor P, Ewers M, Laske C, Priller J, Schneider A, Spottke A, Heneka M, Teipel SJ, Wiltfang J, et al. F4-08-04: Subjective Cognitive Decline, As Measured With A Structured Interview, Is Related To Amyloid Pathology In Cognitively Healthy Older Adults Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.2895  0.375
2018 Roeske S, Wolfsgruber S, Kleineidam L, Zulka L, Buerger K, Ewers M, Laske C, Nestor P, Peters O, Priller J, Schneider A, Spottke A, Ramirez A, Heneka M, Teipel SJ, et al. P3-591: A German Version Of The Lifetime Of Experiences Questionnaire (Leq) To Measure Cognitive Reserve: Validation Results From The Delcode Study Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.1957  0.319
2018 Wolfsgruber S, Kleineidam L, Roeske S, Zulka L, Buerger K, Ewers M, Christoph L, Peters O, Priller J, Nestor P, Schneider A, Spottke A, Ramirez A, Heneka M, Wiltfang J, et al. P1-028: Occupational Cognitive Requirements Are An Important Proxy Measure Of Cognitive Reserve: Evidence From The Agecode And Delcode Studies Alzheimers & Dementia. 14. DOI: 10.1016/J.Jalz.2018.06.029  0.349
2017 Franzmeier N, Hartmann JC, Taylor AN, Araque Caballero MA, Simon-Vermot L, Buerger K, Kambeitz-Ilankovic LM, Ertl-Wagner B, Mueller C, Catak C, Janowitz D, Stahl R, Dichgans M, Duering M, Ewers M. Left Frontal Hub Connectivity during Memory Performance Supports Reserve in Aging and Mild Cognitive Impairment. Journal of Alzheimer's Disease : Jad. PMID 28731448 DOI: 10.3233/JAD-170360  0.3
2017 Brendel M, Kleinberger G, Probst F, Jaworska A, Overhoff F, Blume T, Albert NL, Carlsen J, Lindner S, Gildehaus FJ, Ozmen L, Suárez-Calvet M, Bartenstein P, Baumann K, Ewers M, et al. Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis. Frontiers in Aging Neuroscience. 9: 8. PMID 28197095 DOI: 10.3389/Fnagi.2017.00008  0.31
2017 Franzmeier N, Duering M, Weiner M, Dichgans M, Ewers M. Left frontal cortex connectivity underlies cognitive reserve in prodromal Alzheimer disease. Neurology. PMID 28188306 DOI: 10.1212/Wnl.0000000000003711  0.498
2017 Teipel SJ, Wohlert A, Metzger C, Grimmer T, Sorg C, Ewers M, Meisenzahl E, Klöppel S, Borchardt V, Grothe MJ, Walter M, Dyrba M. Multicenter stability of resting state fMRI in the detection of Alzheimer's disease and amnestic MCI. Neuroimage. Clinical. 14: 183-194. PMID 28180077 DOI: 10.1016/J.Nicl.2017.01.018  0.504
2017 Araque Caballero MÁ, Klöppel S, Dichgans M, Ewers M. Spatial Patterns of Longitudinal Gray Matter Change as Predictors of Concurrent Cognitive Decline in Amyloid Positive Healthy Subjects. Journal of Alzheimer's Disease : Jad. 55: 343-358. PMID 27662291 DOI: 10.3233/Jad-160327  0.541
2017 Franzmeier N, Wolfsgruber S, Ramirez A, Wagner M, Buerger K, Dichgans M, Heneka M, Falkai P, Teipel SJ, Wiltfang J, Priller J, Laske C, Schneider A, Spottke A, Duzel E, ... ... Ewers M, et al. [IC-P-030]: CONNECTIVITY OF THE LEFT FRONTAL CORTEX ATTENUATES DETRIMENTAL EFFECTS OF CSF-TAU ON MEMORY IN PRECLINICAL AND CLINICAL ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P28-P28. DOI: 10.1016/J.Jalz.2017.06.2302  0.423
2017 Ren J, Ye W, Plant C, Araque Caballero MA, Wackersreuther B, Böhm C, Ewers M. [P3-384]: AUTOMATED DETECTION OF EARLY STAGE AD BASED ON COMBINATIONS OF MRI, FDG-PET AND NEUROPSYCHOLOGICAL TESTS Alzheimer's & Dementia. 13: P1106-P1107. DOI: 10.1016/J.Jalz.2017.06.1600  0.364
2017 Franzmeier N, Wolfsgruber S, Ramirez A, Wagner M, Buerger K, Dichgans M, Heneka M, Falkai P, Teipel SJ, Wiltfang J, Priller J, Laske C, Schneider A, Spottke A, Duzel E, ... ... Ewers M, et al. [P2-550]: CONNECTIVITY OF THE LEFT FRONTAL CORTEX ATTENUATES DETRIMENTAL EFFECTS OF CSF-TAU ON MEMORY IN PRECLINICAL AND CLINICAL ALZHEIMER's DISEASE Alzheimer's & Dementia. 13: P854-P855. DOI: 10.1016/j.jalz.2017.06.1208  0.334
2016 Teipel SJ, Grothe MJ, Metzger CD, Grimmer T, Sorg C, Ewers M, Franzmeier N, Meisenzahl E, Klöppel S, Borchardt V, Walter M, Dyrba M. Robust Detection of Impaired Resting State Functional Connectivity Networks in Alzheimer's Disease Using Elastic Net Regularized Regression. Frontiers in Aging Neuroscience. 8: 318. PMID 28101051 DOI: 10.3389/Fnagi.2016.00318  0.428
2016 Franzmeier N, Buerger K, Teipel S, Stern Y, Dichgans M, Ewers M. Cognitive reserve moderates the association between functional network anti-correlations and memory in MCI. Neurobiology of Aging. PMID 28017480 DOI: 10.1016/J.Neurobiolaging.2016.11.013  0.351
2016 Suárez-Calvet M, Araque Caballero MÁ, Kleinberger G, Bateman RJ, Fagan AM, Morris JC, Levin J, Danek A, Ewers M, Haass C. Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injury. Science Translational Medicine. 8: 369ra178. PMID 27974666 DOI: 10.1126/Scitranslmed.Aag1767  0.466
2016 Molinuevo JL, Rabin LA, Amariglio R, Buckley R, Dubois B, Ellis KA, Ewers M, Hampel H, Klöppel S, Rami L, Reisberg B, Saykin AJ, Sikkes S, Smart CM, Snitz BE, et al. Implementation of subjective cognitive decline criteria in research studies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27825022 DOI: 10.1016/J.Jalz.2016.09.012  0.468
2016 Brueggen K, Kasper E, Dyrba M, Bruno D, Pomara N, Ewers M, Duering M, Bürger K, Teipel SJ. The Primacy Effect in Amnestic Mild Cognitive Impairment: Associations with Hippocampal Functional Connectivity. Frontiers in Aging Neuroscience. 8: 244. PMID 27818633 DOI: 10.3389/Fnagi.2016.00244  0.346
2016 Baykara E, Gesierich B, Adam R, Tuladhar AM, Biesbroek JM, Koek HL, Ropele S, Jouvent E, Chabriat H, Ertl-Wagner B, Ewers M, Schmidt R, de Leeuw FE, Biessels GJ, et al. A novel imaging marker for small vessel disease based on skeletonization of white matter tracts and diffusion histograms. Annals of Neurology. PMID 27518166 DOI: 10.1002/Ana.24758  0.399
2016 Dichgans M, Wardlaw J, Smith E, Zietemann V, Seshadri S, Sachdev P, Biessels GJ, Fazekas F, Benavente O, Pantoni L, De Leeuw FE, Norrving B, Matthews P, Chen C, ... ... Ewers M, et al. METACOHORTS for the study of vascular disease and its contribution to cognitive decline and neurodegeneration: An initiative of the Joint Programme for Neurodegenerative Disease Research. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27490018 DOI: 10.1016/J.Jalz.2016.06.004  0.425
2016 Zhang Y, Simon-Vermot L, Araque Caballero MÁ, Gesierich B, Taylor AN, Duering M, Dichgans M, Ewers M. Enhanced resting-state functional connectivity between core memory-task activation peaks is associated with memory impairment in MCI. Neurobiology of Aging. 45: 43-49. PMID 27459924 DOI: 10.1016/J.Neurobiolaging.2016.04.018  0.435
2016 Taylor AN, Kambeitz-Ilankovic L, Gesierich B, Simon-Vermot L, Franzmeier N, Araque Caballero MÁ, Müller S, Hesheng L, Ertl-Wagner B, Bürger K, Weiner MW, Dichgans M, Duering M, Ewers M. Tract-specific white matter hyperintensities disrupt neural network function in Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 27432800 DOI: 10.1016/J.Jalz.2016.06.2358  0.48
2016 Kasper E, Brueggen K, Grothe MJ, Bruno D, Pomara N, Unterauer E, Duering M, Ewers M, Teipel S, Buerger K. Neuronal Correlates of Serial Position Performance in Amnestic Mild Cognitive Impairment. Neuropsychology. PMID 27182709 DOI: 10.1037/Neu0000287  0.368
2016 Suárez-Calvet M, Kleinberger G, Araque Caballero MÁ, Brendel M, Rominger A, Alcolea D, Fortea J, Lleó A, Blesa R, Gispert JD, Sánchez-Valle R, Antonell A, Rami L, Molinuevo JL, Brosseron F, ... ... Ewers M, et al. sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers. Embo Molecular Medicine. PMID 26941262 DOI: 10.15252/Emmm.201506123  0.519
2016 Haass C, Suárez-Calvet M, Kleinberger G, Caballero MÁA, Ewers M. Csf Strem2 Levels Increase In Early Stages Of Autosomal Dominant Alzheimer’S Disease (Adad) And Are Associated With Markers Of Neuronal Injury Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.690  0.305
2016 Wohlert A, Dyrba M, Heine C, Grothe MJ, Grimmer T, Sorg C, Ewers M, Meisenzahl E, Klöppel S, Borchardt V, Walter M, Teipel SJ. Altered Functional Connectivity Of The Default Mode Network In Alzheimer’S Dementia And Mild Cognitive Impairment: Results From A Large-Scale Multicenter Resting-State Fmri Study Alzheimers & Dementia. 12: 945. DOI: 10.1016/J.Jalz.2016.06.1944  0.373
2016 Ewers M, Suarez-Calvet M, Caballero MAA, Kleinberger G, Fagan AM, Moulder KL, Benzinger TLS, Haass C. Csf Levels Of Strem2 Are Associated With Greater Frontal Cortical Thickness During Advanced Disease Stages In Autosomal Dominant Alzheimer Disease Alzheimers & Dementia. 12. DOI: 10.1016/J.Jalz.2016.06.145  0.439
2016 Teipel SJ, Wohlert A, Heine C, Grothe MJ, Grimmer T, Sorg C, Ewers M, Meisenzahl E, Klöppel S, Borchardt V, Walter M, Dyrba M. Functional Connectivity In Alzheimer’S Dementia And Mild Cognitive Impairment: A Large-Scale Multicenter Resting-State Fmri Study Alzheimers & Dementia. 12: 38. DOI: 10.1016/J.Jalz.2016.06.055  0.387
2016 Franzmeier N, Ewers M. Left Prefrontal Global Connectivity Enhances Cognitive Reserve In Alzheimer’S Disease Alzheimers & Dementia. 12: 170. DOI: 10.1016/J.Jalz.2016.06.052  0.38
2015 Araque Caballero MÁ, Brendel M, Delker A, Ren J, Rominger A, Bartenstein P, Dichgans M, Weiner MW, Ewers M. Mapping 3-year changes in gray matter and metabolism in Aβ-positive nondemented subjects. Neurobiology of Aging. 36: 2913-24. PMID 26476234 DOI: 10.1016/J.Neurobiolaging.2015.08.007  0.478
2015 Kim HJ, Im K, Kwon H, Lee JM, Kim C, Kim YJ, Jung NY, Cho H, Ye BS, Noh Y, Kim GH, Ko ED, Kim JS, Choe YS, Lee KH, ... ... Ewers M, et al. Clinical effect of white matter network disruption related to amyloid and small vessel disease. Neurology. 85: 63-70. PMID 26062629 DOI: 10.1212/Wnl.0000000000001705  0.41
2015 Gesierich B, Opherk C, Rosand J, Gonik M, Malik R, Jouvent E, Hervé D, Adib-Samii P, Bevan S, Pianese L, Silvestri S, Dotti MT, De Stefano N, van der Grond J, Boon EM, ... ... Ewers M, et al. APOE ɛ2 is associated with white matter hyperintensity volume in CADASIL. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 25920955 DOI: 10.1038/Jcbfm.2015.85  0.413
2015 Jekel K, Damian M, Wattmo C, Hausner L, Bullock R, Connelly PJ, Dubois B, Eriksdotter M, Ewers M, Graessel E, Kramberger MG, Law E, Mecocci P, Molinuevo JL, Nygård L, et al. Mild cognitive impairment and deficits in instrumental activities of daily living: a systematic review. Alzheimer's Research & Therapy. 7: 17. PMID 25815063 DOI: 10.1186/S13195-015-0099-0  0.387
2015 Ewers M, Mattsson N, Minthon L, Molinuevo JL, Antonell A, Popp J, Jessen F, Herukka SK, Soininen H, Maetzler W, Leyhe T, Bürger K, Taniguchi M, Urakami K, Lista S, et al. CSF biomarkers for the differential diagnosis of Alzheimer's disease. A large-scale international multicenter study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25804998 DOI: 10.1016/J.Jalz.2014.12.006  0.532
2015 Ye BS, Seo SW, Kim GH, Noh Y, Cho H, Yoon CW, Kim HJ, Chin J, Jeon S, Lee JM, Seong JK, Kim JS, Lee JH, Choe YS, Lee KH, ... ... Ewers M, et al. Amyloid burden, cerebrovascular disease, brain atrophy, and cognition in cognitively impaired patients. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 11: 494-503.e3. PMID 25048578 DOI: 10.1016/J.Jalz.2014.04.521  0.514
2015 Taylor ANW, Kambeitz-Ilankovic L, Gesierich B, Simon-Vermot L, Caballero MÁA, Müller S, Heshung L, Ertle-Wagner B, Buerger K, Weiner MW, Dichgans M, Duering M, Ewers M. Tract-specific white matter hyperintensities disrupt the default mode network in Alzheimer’s disease Alzheimers & Dementia. 11. DOI: 10.1016/J.Jalz.2015.07.072  0.3
2015 Simon-Vermot L, Zhang Y, Caballero MÁA, Gesierich B, Kambeitz-Ilankovic L, Brendel M, Rominger A, Bartenstein P, Duering M, Ewers M. Temporo-parietal hypometabolism is associated with reduced functional connectivity of the default mode network in prodromal Alzheimer's disease Alzheimers & Dementia. 11: 542. DOI: 10.1016/J.Jalz.2015.06.684  0.401
2015 Kasper E, Brüggen K, Grothe MJ, Bruno D, Pomara N, Duering M, Ewers M, Buerger K, Teipel SJ. Is hippocampal size associated with primacy recall performance in amnestic mild cognitive impairment Alzheimers & Dementia. 11: 805. DOI: 10.1016/J.Jalz.2015.06.1791  0.371
2015 Zhang Y, Caballero MÁA, Gesierich B, Taylor ANW, Simon-Vermot L, Ewers M. Increased resting state functional connectivity associated with episodic memory impairment in mild cognitive impairment Alzheimers & Dementia. 11: 66. DOI: 10.1016/J.Jalz.2015.06.116  0.358
2015 Franzmeier N, Simon-Vermot L, Caballero MÁA, Taylor ANW, Buerger K, Ewers M. Abnormally reduced anti-correlation between resting-state default mode and fronto-parietal networks is associated with memory impairment in MCI Alzheimers & Dementia. 11: 59. DOI: 10.1016/J.Jalz.2015.06.103  0.311
2015 Caballero MÁA, Klöppel S, Ewers M. Prediction of cognitive decline on the basis of longitudinal changes in whole-brain grey matter: A relevance vector regression analysis Alzheimers & Dementia. 11: 318. DOI: 10.1016/J.Jalz.2015.06.102  0.366
2014 Thal DR, Attems J, Ewers M. Spreading of amyloid, tau, and microvascular pathology in Alzheimer's disease: findings from neuropathological and neuroimaging studies. Journal of Alzheimer's Disease : Jad. 42: S421-9. PMID 25227313 DOI: 10.3233/Jad-141461  0.545
2014 Lautner R, Palmqvist S, Mattsson N, Andreasson U, Wallin A, PÃ¥lsson E, Jakobsson J, Herukka SK, Owenius R, Olsson B, Hampel H, Rujescu D, Ewers M, Landén M, Minthon L, et al. Apolipoprotein E genotype and the diagnostic accuracy of cerebrospinal fluid biomarkers for Alzheimer disease. Jama Psychiatry. 71: 1183-91. PMID 25162367 DOI: 10.1001/Jamapsychiatry.2014.1060  0.504
2014 Kljajevic V, Grothe MJ, Ewers M, Teipel S. Distinct pattern of hypometabolism and atrophy in preclinical and predementia Alzheimer's disease. Neurobiology of Aging. 35: 1973-81. PMID 24811241 DOI: 10.1016/J.Neurobiolaging.2014.04.006  0.537
2014 Noh Y, Seo SW, Jeon S, Lee JM, Kim JH, Kim GH, Cho H, Yoon CW, Kim HJ, Ye BS, Kim ST, Choe YS, Lee KH, Kim JS, Ewers M, et al. White matter hyperintensities are associated with amyloid burden in APOE4 non-carriers. Journal of Alzheimer's Disease : Jad. 40: 877-86. PMID 24577457 DOI: 10.3233/Jad-130461  0.496
2014 Lee MJ, Seo SW, Na DL, Kim C, Park JH, Kim GH, Kim CH, Noh Y, Cho H, Kim HJ, Yoon CW, Ye BS, Chin J, Jeon S, Lee JM, ... ... Ewers M, et al. Synergistic effects of ischemia and β-amyloid burden on cognitive decline in patients with subcortical vascular mild cognitive impairment. Jama Psychiatry. 71: 412-22. PMID 24554306 DOI: 10.1001/Jamapsychiatry.2013.4506  0.486
2014 Lee JY, Park S, Mackin S, Ewers M, Chui H, Jagust W, Insel PS, Weiner MW. Differences in prefrontal, limbic, and white matter lesion volumes according to cognitive status in elderly patients with first-onset subsyndromal depression. Plos One. 9: e87747. PMID 24498184 DOI: 10.1371/Journal.Pone.0087747  0.421
2014 Grothe MJ, Ewers M, Krause B, Heinsen H, Teipel SJ. Basal forebrain atrophy and cortical amyloid deposition in nondemented elderly subjects. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: S344-53. PMID 24418052 DOI: 10.1016/J.Jalz.2013.09.011  0.509
2014 Ewers M, Brendel M, Rizk-Jackson A, Rominger A, Bartenstein P, Schuff N, Weiner MW. Reduced FDG-PET brain metabolism and executive function predict clinical progression in elderly healthy subjects. Neuroimage. Clinical. 4: 45-52. PMID 24286024 DOI: 10.1016/J.Nicl.2013.10.018  0.415
2014 Park JH, Seo SW, Kim C, Kim SH, Kim GH, Kim ST, Jeon S, Lee JM, Oh SJ, Kim JS, Choe YS, Lee KH, Shin JS, Kim CH, Noh Y, ... ... Ewers M, et al. Effects of cerebrovascular disease and amyloid beta burden on cognition in subjects with subcortical vascular cognitive impairment. Neurobiology of Aging. 35: 254-60. PMID 23932881 DOI: 10.1016/J.Neurobiolaging.2013.06.026  0.454
2014 Lista S, Garaci FG, Ewers M, Teipel S, Zetterberg H, Blennow K, Hampel H. CSF Aβ1-42 combined with neuroimaging biomarkers in the early detection, diagnosis and prediction of Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 381-92. PMID 23850330 DOI: 10.1016/J.Jalz.2013.04.506  0.515
2014 Andreasson U, Lautner R, Schott JM, Mattsson N, Hansson O, Herukka SK, Helisalmi S, Ewers M, Hampel H, Wallin A, Minthon L, Hardy J, Blennow K, Zetterberg H. CSF biomarkers for Alzheimer's pathology and the effect size of APOE É›4. Molecular Psychiatry. 19: 148-9. PMID 23419830 DOI: 10.1038/Mp.2013.18  0.5
2014 Taylor ANW, Gesierich B, Simon-Vermot L, Kambeitz-Ilankovic L, Duering M, Ewers M. The Impact Of Fiber-Tract-Specific White Matter Hyperintensities On Resting State Functional Connectivity In Alzheimer'S Disease Alzheimers & Dementia. 10. DOI: 10.1016/J.Jalz.2014.07.084  0.375
2014 Simon-Vermot L, Caballero MÁA, Gesierich B, Kambeitz-Ilankovic L, Duering M, Ewers M. Reduced Resting State Functional Connectivity Associated With Fdg-Pet Hypometabolism In Alzheimer'S Disease Alzheimers & Dementia. 10: 898. DOI: 10.1016/J.Jalz.2014.07.078  0.54
2014 Dyrba M, Ewers M, Plant C, Barkhof F, Fellgiebel A, Hausner L, Filippi M, Kirste T, Teipel SJ. P1-255: PREDICTION OF PRODROMAL AD IN MCI SUBJECTS USING MULTICENTER DTI AND MRI DATA AND MULTIPLE KERNELS SVM: AN EDSD STUDY Alzheimer's & Dementia. 10: P400-P401. DOI: 10.1016/j.jalz.2014.05.495  0.309
2014 Dyrba M, Ewers M, Plant C, Barkhof F, Fellgiebel A, Hausner L, Filippi M, Kirste T, Teipel SJ. IC-P-072: PREDICTION OF PRODROMAL AD IN MCI SUBJECTS USING MULTICENTER DTI AND MRI DATA AND MULTIPLE KERNELS SVM: AN EDSD STUDY Alzheimer's & Dementia. 10: P40-P40. DOI: 10.1016/J.Jalz.2014.05.077  0.394
2014 Caballero MÁA, Brendel M, Delker A, Ren J, Rominger A, Bartenstein P, Weiner MW, Ewers M. O3-03-03: MAPPING 3-YEAR RATES OF DECLINE IN JOINTLY ASSESSED GRAY MATTER VOLUME AND FDG-PET IN Aβ+ NON-DEMENTED SUBJECTS Alzheimer's & Dementia. 10: P212-P212. DOI: 10.1016/J.Jalz.2014.04.282  0.326
2013 Dyrba M, Ewers M, Wegrzyn M, Kilimann I, Plant C, Oswald A, Meindl T, Pievani M, Bokde AL, Fellgiebel A, Filippi M, Hampel H, Klöppel S, Hauenstein K, Kirste T, et al. Robust automated detection of microstructural white matter degeneration in Alzheimer's disease using machine learning classification of multicenter DTI data. Plos One. 8: e64925. PMID 23741425 DOI: 10.1371/Journal.Pone.0064925  0.333
2013 Park JH, Seo SW, Kim C, Kim GH, Noh HJ, Kim ST, Kwak KC, Yoon U, Lee JM, Lee JW, Shin JS, Kim CH, Noh Y, Cho H, Kim HJ, ... ... Ewers M, et al. Pathogenesis of cerebral microbleeds: In vivo imaging of amyloid and subcortical ischemic small vessel disease in 226 individuals with cognitive impairment. Annals of Neurology. 73: 584-93. PMID 23495089 DOI: 10.1002/Ana.23845  0.502
2013 Ewers M, Insel PS, Stern Y, Weiner MW. Cognitive reserve associated with FDG-PET in preclinical Alzheimer disease. Neurology. 80: 1194-201. PMID 23486873 DOI: 10.1212/Wnl.0B013E31828970C2  0.488
2013 Vermeiren AP, Bosma H, Visser PJ, Zeegers MP, Graff C, Ewers M, Frisoni GB, Frölich L, Hampel H, Jones RW, Kehoe PG, Lenoir H, Minthon L, Nobili FM, Olde Rikkert M, et al. The association between APOE ε4 and Alzheimer-type dementia among memory clinic patients is confined to those with a higher education. The DESCRIPA Study. Journal of Alzheimer's Disease : Jad. 35: 241-6. PMID 23380990 DOI: 10.3233/Jad-122182  0.438
2013 Teipel SJ, Sabri O, Grothe M, Barthel H, Prvulovic D, Buerger K, Bokde AL, Ewers M, Hoffmann W, Hampel H. Perspectives for multimodal neurochemical and imaging biomarkers in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 33: S329-47. PMID 22735677 DOI: 10.3233/Jad-2012-129030  0.527
2013 Dyrba M, Ewers M, Wegrzyn M, Plant C, Oswald A, Pievani M, Bokde A, Fellgiebel A, Filippi M, Hausner L, Barkhof F, Hampel H, Klöppel S, Hauenstein K, Kirste T, et al. P2-196: Predicting prodromal Alzheimer's disease in people with mild cognitive impairment using multicenter diffusion-tensor imaging data and machine learning algorithms Alzheimer's & Dementia. 9: P426-P426. DOI: 10.1016/J.Jalz.2013.05.841  0.404
2013 Ewers M, Grothe M, Grinberg L, Heinsen H, Teipel S. P2-195: Basal forebrain atrophy predicts clinical progression in the nondemented elderly Alzheimer's & Dementia. 9: P426-P426. DOI: 10.1016/J.Jalz.2013.05.840  0.405
2013 Andreasson U, Lautner R, Schott J, Mattsson N, Hansson O, Herukka S, Ewers M, Hampel H, Wallin A, Minthon L, Fox N, Hardy J, Blennow K, Zetterberg H. CSF biomarkers for Alzheimer's pathology and the effect size of APOE-ε4 Alzheimers & Dementia. 9: 174. DOI: 10.1016/J.Jalz.2013.05.282  0.45
2013 Kljajevic V, Grothe M, Ewers M, Teipel S. P3-105: Temporal dynamics of imaging biomarkers in predementia stages of Alzheimer's disease Alzheimer's & Dementia. 9: P590-P591. DOI: 10.1016/J.Jalz.2013.05.1176  0.401
2012 Teipel SJ, Wegrzyn M, Meindl T, Frisoni G, Bokde AL, Fellgiebel A, Filippi M, Hampel H, Klöppel S, Hauenstein K, Ewers M. Anatomical MRI and DTI in the diagnosis of Alzheimer's disease: a European multicenter study. Journal of Alzheimer's Disease : Jad. 31: S33-47. PMID 22992380 DOI: 10.3233/Jad-2012-112118  0.433
2012 O'Dwyer L, Lamberton F, Bokde AL, Ewers M, Faluyi YO, Tanner C, Mazoyer B, O'Neill D, Bartley M, Collins R, Coughlan T, Prvulovic D, Hampel H. Sexual dimorphism in healthy aging and mild cognitive impairment: a DTI study. Plos One. 7: e37021. PMID 22768288 DOI: 10.1371/Journal.Pone.0037021  0.346
2012 O'Dwyer L, Lamberton F, Bokde AL, Ewers M, Faluyi YO, Tanner C, Mazoyer B, O'Neill D, Bartley M, Collins DR, Coughlan T, Prvulovic D, Hampel H. Using support vector machines with multiple indices of diffusion for automated classification of mild cognitive impairment. Plos One. 7: e32441. PMID 22384251 DOI: 10.1371/Journal.Pone.0032441  0.363
2012 Mattsson N, Rosén E, Hansson O, Andreasen N, Parnetti L, Jonsson M, Herukka SK, van der Flier WM, Blankenstein MA, Ewers M, Rich K, Kaiser E, Verbeek MM, Olde Rikkert M, Tsolaki M, et al. Age and diagnostic performance of Alzheimer disease CSF biomarkers. Neurology. 78: 468-76. PMID 22302554 DOI: 10.1212/Wnl.0B013E3182477Eed  0.502
2012 Santos AN, Ewers M, Minthon L, Simm A, Silber RE, Blennow K, Prvulovic D, Hansson O, Hampel H. Amyloid-β oligomers in cerebrospinal fluid are associated with cognitive decline in patients with Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 29: 171-6. PMID 22214781 DOI: 10.3233/Jad-2012-111361  0.455
2012 Ewers M, Insel P, Jagust WJ, Shaw L, Trojanowski JQ, Aisen P, Petersen RC, Schuff N, Weiner MW. CSF biomarker and PIB-PET-derived beta-amyloid signature predicts metabolic, gray matter, and cognitive changes in nondemented subjects. Cerebral Cortex (New York, N.Y. : 1991). 22: 1993-2004. PMID 22038908 DOI: 10.1093/Cercor/Bhr271  0.473
2012 Bartley M, Bokde AL, Ewers M, Faluyi YO, Tobin WO, Snow A, Connolly J, Delaney C, Coughlan T, Collins DR, Hampel H, O'Neill D. Subjective memory complaints in community dwelling healthy older people: the influence of brain and psychopathology. International Journal of Geriatric Psychiatry. 27: 836-43. PMID 21953807 DOI: 10.1002/Gps.2794  0.383
2012 Ewers M, Schmitz S, Hansson O, Walsh C, Fitzpatrick A, Bennett D, Minthon L, Trojanowski JQ, Shaw LM, Faluyi YO, Vellas B, Dubois B, Blennow K, Buerger K, Teipel SJ, et al. Body mass index is associated with biological CSF markers of core brain pathology of Alzheimer's disease. Neurobiology of Aging. 33: 1599-608. PMID 21684041 DOI: 10.1016/J.Neurobiolaging.2011.05.005  0.521
2012 Ewers M, Walsh C, Trojanowski JQ, Shaw LM, Petersen RC, Jack CR, Feldman HH, Bokde AL, Alexander GE, Scheltens P, Vellas B, Dubois B, Weiner M, Hampel H. Prediction of conversion from mild cognitive impairment to Alzheimer's disease dementia based upon biomarkers and neuropsychological test performance. Neurobiology of Aging. 33: 1203-14. PMID 21159408 DOI: 10.1016/J.Neurobiolaging.2010.10.019  0.474
2012 Dyrba M, Ewers M, Wegrzyn M, Plant C, Oswald A, Meindl T, Pievani M, Bokde A, Fellgiebel A, Filippi M, Hampel H, Klöppel S, Hauenstein K, Kirste T, Teipel S. P2-234: Automatic detection of Alzheimer's disease in multicenter DTI data Alzheimer's & Dementia. 8: P341-P342. DOI: 10.1016/J.Jalz.2012.05.941  0.426
2012 Lautner R, Zetterberg H, Blennow K, Wallin A, Herukka S, Hampel H, Rujescu D, Ewers M, Mattsson N, Hansson O. The effects of apolipoprotein genotype on the diagnostic accuracy of cerebroispinal fluid biomarkers for Alzheimer's disease Alzheimers & Dementia. 8: 662. DOI: 10.1016/J.Jalz.2012.05.1784  0.433
2012 Ewers M, Schuff N, Weiner M. O3-03-01: Regional FDG-PET brain metabolism is more predictive for clinical progression in cognitively normal subjects than brain atrophy Alzheimer's & Dementia. 8: P431-P432. DOI: 10.1016/J.Jalz.2012.05.1152  0.351
2012 Dyrba M, Ewers M, Wegrzyn M, Plant C, Oswald A, Meindl T, Pievani M, Bokde A, Fellgiebel A, Filippi M, Hampel H, Klöppel S, Hauenstein K, Kirste T, Teipel S. IC-P-036: Automatic detection of Alzheimer's disease in multicenter diffusion tensor imaging data Alzheimer's & Dementia. 8: P24-P25. DOI: 10.1016/J.Jalz.2012.05.068  0.368
2012 Dyrba M, Ewers M, Wegrzyn M, Kilimann I, Plant C, Oswald A, Meindl T, Pievani M, Bokde ALW, Fellgiebel A, Filippi M, Hampel H, Klöppel S, Hauenstein K, Kirste T, et al. Combining DTI and MRI for the automated detection of Alzheimer's disease using a large European multicenter dataset Lecture Notes in Computer Science (Including Subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). 7509: 18-28. DOI: 10.1007/978-3-642-33530-3_2  0.328
2011 Norberg J, Graff C, Almkvist O, Ewers M, Frisoni GB, Frölich L, Hampel H, Jones RW, Kehoe PG, Lenoir H, Minthon L, Nobili F, Olde Rikkert M, Rigaud AS, Scheltens P, et al. Regional differences in effects of APOE ε4 on cognitive impairment in non-demented subjects. Dementia and Geriatric Cognitive Disorders. 32: 135-42. PMID 21952537 DOI: 10.1159/000330492  0.456
2011 O'Dwyer L, Lamberton F, Bokde AL, Ewers M, Faluyi YO, Tanner C, Mazoyer B, O'Neill D, Bartley M, Collins DR, Coughlan T, Prvulovic D, Hampel H. Multiple indices of diffusion identifies white matter damage in mild cognitive impairment and Alzheimer's disease. Plos One. 6: e21745. PMID 21738785 DOI: 10.1371/Journal.Pone.0021745  0.476
2011 Ewers M, Frisoni GB, Teipel SJ, Grinberg LT, Amaro E, Heinsen H, Thompson PM, Hampel H. Staging Alzheimer's disease progression with multimodality neuroimaging. Progress in Neurobiology. 95: 535-46. PMID 21718750 DOI: 10.1016/J.Pneurobio.2011.06.004  0.466
2011 Ewers M, Sperling RA, Klunk WE, Weiner MW, Hampel H. Neuroimaging markers for the prediction and early diagnosis of Alzheimer's disease dementia. Trends in Neurosciences. 34: 430-42. PMID 21696834 DOI: 10.1016/J.Tins.2011.05.005  0.554
2011 O'Dwyer L, Lamberton F, Bokde AL, Ewers M, Faluyi YO, Tanner C, Mazoyer B, O'Neill D, Bartley M, Collins DR, Coughlan T, Prvulovic D, Hampel H. Using diffusion tensor imaging and mixed-effects models to investigate primary and secondary white matter degeneration in Alzheimer's disease and mild cognitive impairment. Journal of Alzheimer's Disease : Jad. 26: 667-82. PMID 21694456 DOI: 10.3233/Jad-2011-110137  0.479
2011 Koppel J, Campagne F, Vingtdeux V, Dreses-Werringloer U, Ewers M, Rujescu D, Hampel H, Gordon ML, Christen E, Chapuis J, Greenwald BS, Davies P, Marambaud P. CALHM1 P86L polymorphism modulates CSF Aβ levels in cognitively healthy individuals at risk for Alzheimer's disease. Molecular Medicine (Cambridge, Mass.). 17: 974-9. PMID 21629967 DOI: 10.2119/molmed.2011.00154  0.412
2011 Ewers M, Cheng X, Zhong Z, Nural HF, Walsh C, Meindl T, Teipel SJ, Buerger K, He P, Shen Y, Hampel H. Increased CSF-BACE1 activity associated with decreased hippocampus volume in Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 25: 373-81. PMID 21460439 DOI: 10.3233/Jad-2011-091153  0.504
2011 Shen Y, Sabbagh M, Nural H, He P, Cheng X, Ewers M, Zhong J, Leyhe T, Wallin A, Blennow K, Li R, Hampel H. P2-067: Significant elevation of plasma BACE in AD and MCI patients Alzheimer's & Dementia. 7: S328-S329. DOI: 10.1016/J.Jalz.2011.05.957  0.394
2011 Faltraco F, Prvulovic D, Ewers M, Müller J, Rujescu D, Hampel H. O3-01-07: PICALM single nucleotide polymorphisms are associated with CSF Aβ1-42 levels in patients with Alzheimer's dementia Alzheimer's & Dementia. 7: S497-S498. DOI: 10.1016/J.Jalz.2011.05.2391  0.436
2011 O'Dwyer L, Lamberton F, Bokde A, Ewers M, Tanner C, Mazoyer B, Faluyi Y, O'Neill D, Bartley M, Collins R, Coughlan T, Prvulovic D, Hampel H. Diffusion tensor imaging identifies hotspots of white matter damage in Alzheimer's disease Alzheimers & Dementia. 7. DOI: 10.1016/J.Jalz.2011.05.096  0.381
2010 Teipel SJ, Ewers M, Wolf S, Jessen F, Kölsch H, Arlt S, Luckhaus C, Schönknecht P, Schmidtke K, Heuser I, Frölich L, Ende G, Pantel J, Wiltfang J, Rakebrandt F, et al. Multicentre variability of MRI-based medial temporal lobe volumetry in Alzheimer's disease. Psychiatry Research. 182: 244-50. PMID 20493672 DOI: 10.1016/J.Pscychresns.2010.03.003  0.528
2010 Ewers M, Cheng X, Nural HF, Walsh C, Meindl T, Teipel SJ, Buerger K, Shen Y, Hampel H. Increased CSF- BACE1 Activity Associated with Decreased Hippocampus Volume in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 20421699 DOI: 10.3233/JAD-2010-091153  0.367
2010 Bokde AL, Karmann M, Born C, Teipel SJ, Omerovic M, Ewers M, Frodl T, Meisenzahl E, Reiser M, Möller HJ, Hampel H. Altered brain activation during a verbal working memory task in subjects with amnestic mild cognitive impairment. Journal of Alzheimer's Disease : Jad. 21: 103-18. PMID 20413893 DOI: 10.3233/Jad-2010-091054  0.394
2010 Plant C, Teipel SJ, Oswald A, Böhm C, Meindl T, Mourao-Miranda J, Bokde AW, Hampel H, Ewers M. Automated detection of brain atrophy patterns based on MRI for the prediction of Alzheimer's disease. Neuroimage. 50: 162-74. PMID 19961938 DOI: 10.1016/J.Neuroimage.2009.11.046  0.497
2010 Ewers M, Mielke MM, Hampel H. Blood-based biomarkers of microvascular pathology in Alzheimer's disease. Experimental Gerontology. 45: 75-9. PMID 19782124 DOI: 10.1016/J.Exger.2009.09.005  0.512
2010 Ewers M, Bokde AL, Park J, Rachakonda S, Teipel SJ, Calhoun V, Hampel H. O2-04-07: Functional connectivity changes during visual processing associated with grey matter atrophy in Alzheimer's disease Alzheimer's & Dementia. 6: S105-S106. DOI: 10.1016/J.Jalz.2010.05.328  0.393
2009 Mattsson N, Zetterberg H, Hansson O, Andreasen N, Parnetti L, Jonsson M, Herukka SK, van der Flier WM, Blankenstein MA, Ewers M, Rich K, Kaiser E, Verbeek M, Tsolaki M, Mulugeta E, et al. CSF biomarkers and incipient Alzheimer disease in patients with mild cognitive impairment. Jama. 302: 385-93. PMID 19622817 DOI: 10.1001/Jama.2009.1064  0.485
2009 Hampel H, Ewers M, Bürger K, Annas P, Mörtberg A, Bogstedt A, Frölich L, Schröder J, Schönknecht P, Riepe MW, Kraft I, Gasser T, Leyhe T, Möller HJ, Kurz A, et al. Lithium trial in Alzheimer's disease: a randomized, single-blind, placebo-controlled, multicenter 10-week study. The Journal of Clinical Psychiatry. 70: 922-31. PMID 19573486 DOI: 10.4088/Jcp.08M04606  0.417
2009 Bokde AL, Ewers M, Hampel H. Assessing neuronal networks: understanding Alzheimer's disease. Progress in Neurobiology. 89: 125-33. PMID 19560509 DOI: 10.1016/J.Pneurobio.2009.06.004  0.487
2009 Buerger K, Frisoni G, Uspenskaya O, Ewers M, Zetterberg H, Geroldi C, Binetti G, Johannsen P, Rossini PM, Wahlund LO, Vellas B, Blennow K, Hampel H. Validation of Alzheimer's disease CSF and plasma biological markers: the multicentre reliability study of the pilot European Alzheimer's Disease Neuroimaging Initiative (E-ADNI). Experimental Gerontology. 44: 579-85. PMID 19539742 DOI: 10.1016/J.Exger.2009.06.003  0.518
2009 Buerger K, Ernst A, Ewers M, Uspenskaya O, Omerovic M, Morgenthaler NG, Knauer K, Bergmann A, Hampel H. Blood-based microcirculation markers in Alzheimer's disease-diagnostic value of midregional pro-atrial natriuretic peptide/C-terminal endothelin-1 precursor fragment ratio. Biological Psychiatry. 65: 979-84. PMID 19344890 DOI: 10.1016/J.Biopsych.2009.01.032  0.389
2009 Ewers M, Walsh C, Trojanowski JQ, Shaw LM, Sheltens P, Bokde AL, Feldman H, Alexander GE, Dubois B, Hampel H. P4-332: Biomarker Based Diagnosis Of Very Mild Alzheimer's Disease: A Multicenter Study Alzheimer's & Dementia. 5: e28-e28. DOI: 10.1016/J.Jalz.2009.07.111  0.458
2009 Ewers M, Bokde ALW, Walsh C, Hampel H. Multidimensional biomarker-based diagnosis of early Alzheimer's disease Alzheimers & Dementia. 5. DOI: 10.1016/J.Jalz.2009.05.463  0.441
2009 Shen Y, Sabbagh M, Nural H, He P, Cheng X, Ewers M, Hampel H. O3-04-06: Significantly altered BACE1 levels have been found in the blood of Alzheimer's disease and MCI subjects Alzheimer's & Dementia. 5: P134-P134. DOI: 10.1016/J.Jalz.2009.05.453  0.419
2009 Ewers M. S2-01-04: Association between CSF phosphorylated tau and risk factors of Alzheimer's disease Alzheimer's & Dementia. 5: P93-P93. DOI: 10.1016/J.Jalz.2009.05.248  0.435
2009 Ewers M, Faluyi Y, Buerger K, Teipel SJ, Bokde AL, Hampel H. P2-075: Lower body mass index associated with higher CSF levels of tau pathology in Alzheimer's Disease Alzheimer's & Dementia. 5: P284-P284. DOI: 10.1016/J.Jalz.2009.04.385  0.442
2009 Bokde A, Ewers M, Faluyi Y, Delaney C, Khattack A, Collins R, Kerskens C, Coughlan T, Nibrihain S, Daly I, Swanwick G, O'Neill D, Hampel H. P3-083: Alterations in activation between mild cognitive impaired subjects during a working memory task and resting coherent network Alzheimer's & Dementia. 5: P366-P366. DOI: 10.1016/J.Jalz.2009.04.1159  0.342
2009 Bokde A, Ewers M, Lopez-Bayo P, Born C, Meindl T, Teipel SJ, Reiser M, Moeller H, Hampel H. Functional connectivity alterations of visual processing in Alzheimer's disease Alzheimers & Dementia. 5. DOI: 10.1016/J.Jalz.2009.04.092  0.398
2008 Ewers M, Zhong Z, Bürger K, Wallin A, Blennow K, Teipel SJ, Shen Y, Hampel H. Increased CSF-BACE 1 activity is associated with ApoE-epsilon 4 genotype in subjects with mild cognitive impairment and Alzheimer's disease. Brain : a Journal of Neurology. 131: 1252-8. PMID 18334538 DOI: 10.1093/Brain/Awn034  0.527
2008 Ewers M, Bokde AL, Teipel SJ, Beil S, Born C, Reiser M, Hampel H. P1-242: Altered hippocampus functional connectivity in the recognition memory network corrected for grey matter atrophy in mild cognitive impairment Alzheimer's & Dementia. 4: T286-T286. DOI: 10.1016/J.Jalz.2008.05.831  0.368
2008 Hampel H, Ewers M, Zhong Z, Bürger K, Wallin A, Du Y, Blennow K, Shen Y. O3-02-03: Alteration of beta secretase (BACE1) functional candidate biomarkers in subjects with mild cognitive impairment and Alzheimer's disease Alzheimer's & Dementia. 4: T160-T160. DOI: 10.1016/J.Jalz.2008.05.416  0.452
2008 Teipel SJ, Ewers M, Wolf S, Jessen F, Peters O, Born C, Kornhuber J, Hampel H. IC-P2-141: Multicentre variability of MRI-based medial temporal lobe volumetry in Alzheimer's disease: A longitudinal study Alzheimer's & Dementia. 4: T62-T63. DOI: 10.1016/J.Jalz.2008.05.2595  0.402
2008 Hampel H, Ewers M, Bürger K, Annas P, Mörtberg A, Bogstedt A, Frölich L, Schröder J, Schönknecht P, Riepe M, Kraft I, Gasser T, Leyhe T, Kurz A, Basun H. P4-369: Lithium trial in Alzheimer's disease: A randomized, single-blinded, placebo-controlled, parallel group multicentre 10-week study Alzheimer's & Dementia. 4: T782-T782. DOI: 10.1016/J.Jalz.2008.05.2440  0.352
2008 Li R, Zhong J, Chen X, Song Y, Lee T, Pierce N, Ewers M, Blennow K, Hampel H. P3-083: Beta-secretase levels changed in mild cognitive impairment patients' brains and cerebral spinal fluid Alzheimer's & Dementia. 4: T542-T542. DOI: 10.1016/J.Jalz.2008.05.1647  0.364
2008 Ewers M, Zhong Z, Bürger K, Wallin A, Blennow K, Teipel SJ, Shen Y, Hampel H. P3-069: Increased CSF-BACE1 activity is associated with APOE-ϵ4 genotype in subjects with mild cognitive impairment and Alzheimer's disease Alzheimer's & Dementia. 4: T538-T538. DOI: 10.1016/J.Jalz.2008.05.1633  0.521
2007 Ewers M, Buerger K, Teipel SJ, Scheltens P, Schröder J, Zinkowski RP, Bouwman FH, Schönknecht P, Schoonenboom NS, Andreasen N, Wallin A, DeBernardis JF, Kerkman DJ, Heindl B, Blennow K, et al. Multicenter assessment of CSF-phosphorylated tau for the prediction of conversion of MCI. Neurology. 69: 2205-12. PMID 18071141 DOI: 10.1212/01.Wnl.0000286944.22262.Ff  0.46
2007 Teipel SJ, Born C, Ewers M, Bokde AL, Reiser MF, Möller HJ, Hampel H. Multivariate deformation-based analysis of brain atrophy to predict Alzheimer's disease in mild cognitive impairment. Neuroimage. 38: 13-24. PMID 17827035 DOI: 10.1016/J.Neuroimage.2007.07.008  0.497
2007 Buerger K, Alafuzoff I, Ewers M, Pirttilä T, Zinkowski R, Hampel H. No correlation between CSF tau protein phosphorylated at threonine 181 with neocortical neurofibrillary pathology in Alzheimer's disease. Brain : a Journal of Neurology. 130: e82. PMID 17615094 DOI: 10.1093/Brain/Awm140  0.455
2007 Zhong Z, Ewers M, Teipel S, Bürger K, Wallin A, Blennow K, He P, McAllister C, Hampel H, Shen Y. Levels of beta-secretase (BACE1) in cerebrospinal fluid as a predictor of risk in mild cognitive impairment. Archives of General Psychiatry. 64: 718-26. PMID 17548753 DOI: 10.1001/Archpsyc.64.6.718  0.439
2007 Teipel SJ, Ewers M, Reisig V, Schweikert B, Hampel H, Happich M. Long-term cost-effectiveness of donepezil for the treatment of Alzheimer's disease. European Archives of Psychiatry and Clinical Neuroscience. 257: 330-6. PMID 17404699 DOI: 10.1007/S00406-007-0727-1  0.367
2007 Yamamori H, Khatoon S, Grundke-Iqbal I, Blennow K, Ewers M, Hampel H, Iqbal K. Tau in cerebrospinal fluid: a sensitive sandwich enzyme-linked immunosorbent assay using tyramide signal amplification. Neuroscience Letters. 418: 186-9. PMID 17400380 DOI: 10.1016/J.Neulet.2007.03.022  0.402
2007 Sydykova D, Stahl R, Dietrich O, Ewers M, Reiser MF, Schoenberg SO, Möller HJ, Hampel H, Teipel SJ. Fiber connections between the cerebral cortex and the corpus callosum in Alzheimer's disease: a diffusion tensor imaging and voxel-based morphometry study. Cerebral Cortex (New York, N.Y. : 1991). 17: 2276-82. PMID 17164468 DOI: 10.1093/Cercor/Bhl136  0.429
2006 Buerger K, Ewers M, Pirttilä T, Zinkowski R, Alafuzoff I, Teipel SJ, DeBernardis J, Kerkman D, McCulloch C, Soininen H, Hampel H. CSF phosphorylated tau protein correlates with neocortical neurofibrillary pathology in Alzheimer's disease. Brain : a Journal of Neurology. 129: 3035-41. PMID 17012293 DOI: 10.1093/Brain/Awl269  0.455
2006 Ewers M, Teipel SJ, Dietrich O, Schönberg SO, Jessen F, Heun R, Scheltens P, van de Pol L, Freymann NR, Moeller HJ, Hampel H. Multicenter assessment of reliability of cranial MRI. Neurobiology of Aging. 27: 1051-9. PMID 16169126 DOI: 10.1016/J.Neurobiolaging.2005.05.032  0.407
2006 Teipel S, Ewers M, Dietrich O, Schoenberg S, Jessen F, Heun R, Freymann N, Möller HJ, Hampel H. [Reliability of multicenter magnetic resonance imaging. Results of a phantom test and in vivo measurements by the German Dementia Competence Network]. Der Nervenarzt. 77: 1086-92, 1094-5. PMID 15986259 DOI: 10.1007/S00115-005-1948-Z  0.413
2006 Hampel H, Ewers M, Born C, Stefan SO, Teipel SJ. P1-337: Mapping of neuronatomical changes associated with APOE genotype in Alzheimer's disease Alzheimer's & Dementia. 2: S196-S196. DOI: 10.1016/j.jalz.2006.05.715  0.319
2006 Ewers M, Hampel H, Born C, Schoenberg SO, Moeller H, Teipel SJ. IC-P-065: Mapping of neuronatomical changes associated with ApoE genotype in Alzheimer's disease Alzheimer's & Dementia. 2: S679-S679. DOI: 10.1016/J.Jalz.2006.05.2270  0.403
2006 Ewers M, Teipel SJ, Born C, Moeller H, Hampel H. IC-P-060: Multicenter voxel-based morphometry of regional grey matter changes in Alzheimer's disease and MCI Alzheimer's & Dementia. 2: S677-S677. DOI: 10.1016/J.Jalz.2006.05.2265  0.436
2006 Ewers M, Teipel SJ, Born C, Möller H, Hampel H. S3-01-03: Multi center MR imaging of dementia Alzheimer's & Dementia. 2: S46-S46. DOI: 10.1016/J.Jalz.2006.05.162  0.333
2006 Ewers M, Teipel SJ, Born C, Moeller H, Hampel H. P2-323: Multicenter voxel-based morphometry of regional grey matter changes and manual volumetry in Alzheimer's disease and MCI Alzheimer's & Dementia. 2: S336-S336. DOI: 10.1016/J.Jalz.2006.05.1163  0.472
2005 Buerger K, Ewers M, Andreasen N, Zinkowski R, Ishiguro K, Vanmechelen E, Teipel SJ, Graz C, Blennow K, Hampel H. Phosphorylated tau predicts rate of cognitive decline in MCI subjects: a comparative CSF study. Neurology. 65: 1502-3. PMID 16275849 DOI: 10.1212/01.Wnl.0000183284.92920.F2  0.499
2005 Buerger K, Teipel SJ, Zinkowski R, Sunderland T, Andreasen N, Blennow K, Ewers M, DeBernardis J, Shen Y, Kerkman D, Du Y, Hampel H. Increased levels of CSF phosphorylated tau in apolipoprotein E epsilon4 carriers with mild cognitive impairment. Neuroscience Letters. 391: 48-50. PMID 16165272 DOI: 10.1016/J.Neulet.2005.08.030  0.518
2005 Hampel H, Haslinger A, Scheloske M, Padberg F, Fischer P, Unger J, Teipel SJ, Neumann M, Rosenberg C, Oshida R, Hulette C, Pongratz D, Ewers M, Kretzschmar HA, Möller HJ. Pattern of interleukin-6 receptor complex immunoreactivity between cortical regions of rapid autopsy normal and Alzheimer's disease brain. European Archives of Psychiatry and Clinical Neuroscience. 255: 269-78. PMID 15565298 DOI: 10.1007/S00406-004-0558-2  0.319
2005 Hampel H, Ewers M, Bokde A, Teipel S. [S1-01-02]: MRI-based methods for diagnosing and measuring progression of AD Alzheimer's & Dementia. 1: S7-S7. DOI: 10.1016/J.Jalz.2005.06.056  0.424
2005 Ewers M, Teipel SJ, Hampel H. Update of structural MRI-based methods for the early detection of Alzheimer's disease | Aktuelle entwicklungen der strukturellen MRT zur frühdiagnostik der Alzheimer-demenz Nervenheilkunde. 24: 113-119.  0.359
2004 Ewers M, Teipel SJ, Hartman V, Bokde A, Drzega A, Schwaiger M, Leinsinger G, Möller H, Hampel H. P3-057 Frontal cortical response to audiovisual stimulation during 18FDG PET in patients with Alzheimer disease and depressive symptoms Neurobiology of Aging. 25: S367. DOI: 10.1016/S0197-4580(04)81209-0  0.349
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