Michael T. Heneka - Publications

Affiliations: 
University of Bonn, Bonn, Nordrhein-Westfalen, Germany 
Area:
Neurodegeneration

176 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Teipel SJ, Kuper-Smith JO, Bartels C, Brosseron F, Buchmann M, Buerger K, Catak C, Janowitz D, Dechent P, Dobisch L, Ertl-Wagner B, Fließbach K, Haynes JD, Heneka MT, Kilimann I, et al. Multicenter Tract-Based Analysis of Microstructural Lesions within the Alzheimer's Disease Spectrum: Association with Amyloid Pathology and Diagnostic Usefulness. Journal of Alzheimer's Disease : Jad. PMID 31594223 DOI: 10.3233/JAD-190446  0.4
2019 Berron D, Cardenas-Blanco A, Bittner D, Metzger CD, Spottke A, Heneka MT, Fließbach K, Schneider A, Teipel SJ, Wagner M, Speck O, Jessen F, Düzel E. Higher CSF tau levels are related to hippocampal hyperactivity and object mnemonic discrimination in older adults. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31541019 DOI: 10.1523/JNEUROSCI.1279-19.2019  0.4
2019 Wijasa TS, Sylvester M, Brocke-Ahmadinejad N, Schwartz S, Santarelli F, Gieselmann V, Klockgether T, Brosseron F, Heneka MT. Quantitative proteomics of synaptosome S-nitrosylation in Alzheimer's disease. Journal of Neurochemistry. PMID 31520481 DOI: 10.1111/jnc.14870  0.72
2019 Karsak M, Glebov K, Scheffold M, Bajaj T, Kawalia A, Karaca I, Rading S, Kornhuber J, Peters O, Diez-Fairen M, Frölich L, Hüll M, Wiltfang J, Scherer M, Riedel-Heller S, ... ... Heneka MT, et al. A rare heterozygous TREM2 coding variant identified in familial clustering of dementia affects an intrinsically disordered protein region and function of TREM2. Human Mutation. PMID 31464095 DOI: 10.1002/humu.23904  0.48
2019 Miebach L, Wolfsgruber S, Polcher A, Peters O, Menne F, Luther K, Incesoy E, Priller J, Spruth E, Altenstein S, Buerger K, Catak C, Janowitz D, Perneczky R, Utecht J, ... ... Heneka MT, et al. Which features of subjective cognitive decline are related to amyloid pathology? Findings from the DELCODE study. Alzheimer's Research & Therapy. 11: 66. PMID 31366409 DOI: 10.1186/s13195-019-0515-y  0.4
2019 Tejera D, Mercan D, Sanchez-Caro JM, Hanan M, Greenberg D, Soreq H, Latz E, Golenbock D, Heneka MT. Systemic inflammation impairs microglial Aβ clearance through NLRP3 inflammasome. The Embo Journal. e101064. PMID 31359456 DOI: 10.15252/embj.2018101064  0.68
2019 Nitsch L, Zimmermann J, Krauthausen M, Hofer MJ, Saggu R, Petzold GC, Heneka MT, Getts DR, Becker A, Campbell IL, Müller M. CNS-Specific Synthesis of Interleukin 23 Induces a Progressive Cerebellar Ataxia and the Accumulation of Both T and B Cells in the Brain: Characterization of a Novel Transgenic Mouse Model. Molecular Neurobiology. PMID 31154574 DOI: 10.1007/s12035-019-1640-0  0.44
2019 Franzmeier N, Ren J, Damm A, Monté-Rubio G, Boada M, Ruiz A, Ramirez A, Jessen F, Düzel E, Rodríguez Gómez O, Benzinger T, Goate A, Karch CM, Fagan AM, McDade E, ... ... Heneka MT, et al. The BDNF SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease. Molecular Psychiatry. PMID 30899092 DOI: 10.1038/s41380-019-0404-6  0.4
2019 Herrera-Rivero M, Santarelli F, Brosseron F, Kummer MP, Heneka MT. Dysregulation of TLR5 and TAM Ligands in the Alzheimer's Brain as Contributors to Disease Progression. Molecular Neurobiology. PMID 30852796 DOI: 10.1007/s12035-019-1540-3  1
2019 Heneka MT, McManus RM, Latz E. Author Correction: Inflammasome signalling in brain function and neurodegenerative disease. Nature Reviews. Neuroscience. PMID 30742056 DOI: 10.1038/s41583-019-0137-1  0.68
2019 Wolfsgruber S, Molinuevo JL, Wagner M, Teunissen CE, Rami L, Coll-Padrós N, Bouwman FH, Slot RER, Wesselman LMP, Peters O, Luther K, Buerger K, Priller J, Laske C, Teipel S, ... ... Heneka MT, et al. Prevalence of abnormal Alzheimer's disease biomarkers in patients with subjective cognitive decline: cross-sectional comparison of three European memory clinic samples. Alzheimer's Research & Therapy. 11: 8. PMID 30654834 DOI: 10.1186/s13195-018-0463-y  0.4
2018 Hu X, Teunissen C, Spottke A, Heneka MT, Düzel E, Peters O, Li S, Priller J, Bürger K, Teipel S, Laske C, Verfaillie S, Barkhof F, Coll-Padrós N, Rami L, et al. Smaller medial temporal lobe volumes in individuals with subjective cognitive decline and biomarker evidence of Alzheimer's disease-Data from three memory clinic studies. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30321506 DOI: 10.1016/j.jalz.2018.09.002  0.4
2018 Heneka MT, McManus RM, Latz E. Inflammasome signalling in brain function and neurodegenerative disease. Nature Reviews. Neuroscience. PMID 30206330 DOI: 10.1038/s41583-018-0055-7  0.68
2018 Tzeng TC, Hasegawa Y, Iguchi R, Cheung A, Caffrey DR, Thatcher EJ, Mao W, Germain G, Tamburro ND, Okabe S, Heneka MT, Latz E, Futai K, Golenbock DT. Inflammasome-derived cytokine IL18 suppresses amyloid-induced seizures in Alzheimer-prone mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 30127003 DOI: 10.1073/pnas.1801802115  0.68
2018 Teipel SJ, Metzger C, Brosseron F, Buerger K, Brueggen K, Catak C, Diesing D, Dobisch L, Fliebach K, Franke C, Heneka M, Kilimann I, Kofler B, Menne F, Peters O, et al. Multicenter Resting State Functional Connectivity in Prodromal and Dementia Stages of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 29914027 DOI: 10.3233/JAD-180106  0.4
2018 Kalinin S, González-Prieto M, Scheiblich H, Lisi L, Kusumo H, Heneka MT, Madrigal JLM, Pandey SC, Feinstein DL. Transcriptome analysis of alcohol-treated microglia reveals downregulation of beta amyloid phagocytosis. Journal of Neuroinflammation. 15: 141. PMID 29759078 DOI: 10.1186/s12974-018-1184-7  1
2018 Enkirch SJ, Traschütz A, Müller A, Widmann CN, Gielen GH, Heneka MT, Jurcoane A, Schild HH, Hattingen E. The ERICA Score: An MR Imaging-based Visual Scoring System for the Assessment of Entorhinal Cortex Atrophy in Alzheimer Disease. Radiology. 171888. PMID 29514015 DOI: 10.1148/radiol.2018171888  0.52
2018 Brosseron F, Traschütz A, Widmann CN, Kummer MP, Tacik P, Santarelli F, Jessen F, Heneka MT. Characterization and clinical use of inflammatory cerebrospinal fluid protein markers in Alzheimer's disease. Alzheimer's Research & Therapy. 10: 25. PMID 29482610 DOI: 10.1186/s13195-018-0353-3  1
2018 Franzmeier N, Düzel E, Jessen F, Buerger K, Levin J, Duering M, Dichgans M, Haass C, Suárez-Calvet M, Fagan AM, Paumier K, Benzinger T, Masters CL, Morris JC, Perneczky R, ... ... Heneka MT, et al. Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer's disease. Brain : a Journal of Neurology. PMID 29462334 DOI: 10.1093/brain/awy008  0.4
2018 Jessen F, Spottke A, Boecker H, Brosseron F, Buerger K, Catak C, Fliessbach K, Franke C, Fuentes M, Heneka MT, Janowitz D, Kilimann I, Laske C, Menne F, Nestor P, et al. Design and first baseline data of the DZNE multicenter observational study on predementia Alzheimer's disease (DELCODE). Alzheimer's Research & Therapy. 10: 15. PMID 29415768 DOI: 10.1186/s13195-017-0314-2  0.4
2017 Venegas C, Kumar S, Franklin BS, Dierkes T, Brinkschulte R, Tejera D, Vieira-Saecker A, Schwartz S, Santarelli F, Kummer MP, Griep A, Gelpi E, Beilharz M, Riedel D, Golenbock DT, ... ... Heneka MT, et al. Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer's disease. Nature. 552: 355-361. PMID 29293211 DOI: 10.1038/nature25158  1
2017 Ardura-Fabregat A, Boddeke EWGM, Boza-Serrano A, Brioschi S, Castro-Gomez S, Ceyzériat K, Dansokho C, Dierkes T, Gelders G, Heneka MT, Hoeijmakers L, Hoffmann A, Iaccarino L, Jahnert S, Kuhbandner K, et al. Targeting Neuroinflammation to Treat Alzheimer's Disease. Cns Drugs. PMID 29260466 DOI: 10.1007/s40263-017-0483-3  0.32
2017 Traschütz A, Kummer MP, Schwartz S, Heneka MT. Variability and temporal dynamics of novel object recognition in aging male C57BL/6 mice. Behavioural Processes. PMID 29155004 DOI: 10.1016/j.beproc.2017.11.009  1
2017 Labzin LI, Heneka MT, Latz E. Innate Immunity and Neurodegeneration. Annual Review of Medicine. PMID 29106805 DOI: 10.1146/annurev-med-050715-104343  0.68
2017 Scheiblich H, Schlütter A, Golenbock DT, Latz E, Martinez-Martinez P, Heneka MT. Activation of the NLRP3 inflammasome in microglia: The role of ceramide. Journal of Neurochemistry. PMID 28940479 DOI: 10.1111/jnc.14225  0.68
2017 Müller S, Preische O, Göpfert JC, Yañez VAC, Joos TO, Boecker H, Düzel E, Falkai P, Priller J, Buerger K, Catak C, Janowitz D, Heneka MT, Brosseron F, Nestor P, et al. Tau plasma levels in subjective cognitive decline: Results from the DELCODE study. Scientific Reports. 7: 9529. PMID 28842559 DOI: 10.1038/s41598-017-08779-0  0.4
2017 Wijasa TS, Sylvester M, Brocke-Ahmadinejad N, Kummer MP, Brosseron F, Gieselmann V, Heneka MT. Proteome profiling of s-nitrosylated synaptosomal proteins by isobaric mass tags. Journal of Neuroscience Methods. PMID 28789995 DOI: 10.1016/j.jneumeth.2017.08.005  1
2017 Netea MG, Balkwill F, Chonchol M, Cominelli F, Donath MY, Giamarellos-Bourboulis EJ, Golenbock D, Gresnigt MS, Heneka MT, Hoffman HM, Hotchkiss R, Joosten LAB, Kastner DL, Korte M, Latz E, et al. A guiding map for inflammation. Nature Immunology. 18: 826-831. PMID 28722720 DOI: 10.1038/ni.3790  0.68
2017 Zimmermann J, Emrich M, Krauthausen M, Saxe S, Nitsch L, Heneka MT, Campbell IL, Müller M. IL-17A Promotes Granulocyte Infiltration, Myelin Loss, Microglia Activation, and Behavioral Deficits During Cuprizone-Induced Demyelination. Molecular Neurobiology. PMID 28084589 DOI: 10.1007/s12035-016-0368-3  0.44
2016 van der Zee J, Gijselinck I, Van Mossevelde S, Perrone F, Dillen L, Heeman B, Bäumer V, Engelborghs S, De Bleecker J, Baets J, Gelpi E, Rojas-García R, Clarimón J, Lleó A, Diehl-Schmid J, ... ... Heneka MT, et al. TBK1 Mutation Spectrum in an Extended European Patient Cohort With Frontotemporal Dementia and Amyotrophic Lateral Sclerosis. Human Mutation. PMID 28008748 DOI: 10.1002/humu.23161  0.4
2016 Zimmer S, Grebe A, Bakke SS, Bode N, Halvorsen B, Ulas T, Skjelland M, De Nardo D, Labzin LI, Kerksiek A, Hempel C, Heneka MT, Hawxhurst V, Fitzgerald ML, Trebicka J, et al. Cyclodextrin promotes atherosclerosis regression via macrophage reprogramming. Science Translational Medicine. 8: 333ra50. PMID 27053774 DOI: 10.1126/scitranslmed.aad6100  1
2016 Suárez-Calvet M, Kleinberger G, Araque Caballero MÁ, Brendel M, Rominger A, Alcolea D, Fortea J, Lleó A, Blesa R, Gispert JD, Sánchez-Valle R, Antonell A, Rami L, Molinuevo JL, Brosseron F, ... ... Heneka MT, et al. sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers. Embo Molecular Medicine. PMID 26941262 DOI: 10.15252/emmm.201506123  1
2015 Traschütz A, Tzaridis T, Penner AH, Kuchelmeister K, Urbach H, Hattingen E, Heneka MT. Reduction of microbleeds by immunosuppression in a patient with Aβ-related vascular inflammation. Neurology® Neuroimmunology & Neuroinflammation. 2: e165. PMID 26516630 DOI: 10.1212/NXI.0000000000000165  1
2015 Willem M, Tahirovic S, Busche MA, Ovsepian SV, Chafai M, Kootar S, Hornburg D, Evans LD, Moore S, Daria A, Hampel H, Müller V, Giudici C, Nuscher B, Wenninger-Weinzierl A, ... ... Heneka MT, et al. η-Secretase processing of APP inhibits neuronal activity in the hippocampus. Nature. PMID 26322584 DOI: 10.1038/nature14864  1
2015 Hong GS, Schwandt T, Stein K, Schneiker B, Kummer MP, Heneka MT, Kitamura K, Kalff JC, Wehner S. Effects of macrophage-dependent peroxisome proliferator-activated receptor γ signalling on adhesion formation after abdominal surgery in an experimental model. The British Journal of Surgery. PMID 26313905 DOI: 10.1002/bjs.9907  1
2015 Bach JP, Gold M, Mengel D, Hattesohl A, Lubbe D, Schmid S, Tackenberg B, Rieke J, Maddula S, Baumbach JI, Nell C, Boeselt T, Michelis J, Alferink J, Heneka M, et al. Measuring Compounds in Exhaled Air to Detect Alzheimer's Disease and Parkinson's Disease. Plos One. 10: e0132227. PMID 26168044 DOI: 10.1371/journal.pone.0132227  1
2015 Heneka MT, Fink A, Doblhammer G. Effect of pioglitazone medication on the incidence of dementia. Annals of Neurology. 78: 284-94. PMID 25974006 DOI: 10.1002/ana.24439  1
2015 Heilmann S, Drichel D, Clarimon J, Fernández V, Lacour A, Wagner H, Thelen M, Hernández I, Fortea J, Alegret M, Blesa R, Mauleón A, Roca MR, Kornhuber J, Peters O, ... ... Heneka MT, et al. PLD3 in non-familial Alzheimer's disease. Nature. 520: E3-5. PMID 25832411 DOI: 10.1038/nature14039  1
2015 Schmidt R, Hofer E, Bouwman FH, Buerger K, Cordonnier C, Fladby T, Galimberti D, Georges J, Heneka MT, Hort J, Laczó J, Molinuevo JL, O'Brien JT, Religa D, Scheltens P, et al. EFNS-ENS/EAN Guideline on concomitant use of cholinesterase inhibitors and memantine in moderate to severe Alzheimer's disease. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 22: 889-98. PMID 25808982 DOI: 10.1111/ene.12707  1
2015 Heneka MT, Carson MJ, El Khoury J, Landreth GE, Brosseron F, Feinstein DL, Jacobs AH, Wyss-Coray T, Vitorica J, Ransohoff RM, Herrup K, Frautschy SA, Finsen B, Brown GC, Verkhratsky A, et al. Neuroinflammation in Alzheimer's disease. The Lancet. Neurology. 14: 388-405. PMID 25792098 DOI: 10.1016/S1474-4422(15)70016-5  1
2015 Heneka MT, Golenbock DT, Latz E. Innate immunity in Alzheimer's disease. Nature Immunology. 16: 229-36. PMID 25689443 DOI: 10.1038/ni.3102  1
2015 Kurzwelly D, Krüger S, Biskup S, Heneka MT. A distinct clinical phenotype in a German kindred with motor neuron disease carrying a CHCHD10 mutation. Brain : a Journal of Neurology. PMID 25681414 DOI: 10.1093/brain/awv014  1
2015 Krauthausen M, Kummer MP, Zimmermann J, Reyes-Irisarri E, Terwel D, Bulic B, Heneka MT, Müller M. CXCR3 promotes plaque formation and behavioral deficits in an Alzheimer's disease model. The Journal of Clinical Investigation. 125: 365-78. PMID 25500888 DOI: 10.1172/JCI66771  1
2015 Meiberth D, Scheef L, Wolfsgruber S, Boecker H, Block W, Träber F, Erk S, Heneka MT, Jacobi H, Spottke A, Walter H, Wagner M, Hu X, Jessen F. Cortical thinning in individuals with subjective memory impairment. Journal of Alzheimer's Disease : Jad. 45: 139-46. PMID 25471190 DOI: 10.3233/JAD-142322  1
2015 Kummer MP, Schwarzenberger R, Sayah-Jeanne S, Dubernet M, Walczak R, Hum DW, Schwartz S, Axt D, Heneka MT. Pan-PPAR modulation effectively protects APP/PS1 mice from amyloid deposition and cognitive deficits. Molecular Neurobiology. 51: 661-71. PMID 24838579 DOI: 10.1007/s12035-014-8743-4  1
2015 Lindlau A, Widmann CN, Putensen C, Jessen F, Semmler A, Heneka MT. Predictors of hippocampal atrophy in critically ill patients. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 22: 410-5. PMID 24724819 DOI: 10.1111/ene.12443  1
2015 Traschütz A, Heneka MT. Neuroinflammation in Neurodegenerative Disease | Neuroinflammation bei neurodegenerativen Erkrankungen Aktuelle Neurologie. 42: 402-410. DOI: 10.1055/s-0035-1552714  1
2015 Rosengarten B, Heneka MT, Axer H. Current aspects of sepsis therapy on neurointensive care units: part 2: Sepsis-related encephalopathy | Aktuelle Therapie der Sepsis auf der neurologischen Intensivstation: Teil 2: Septische Enzephalopathie Aktuelle Neurologie. 42: 148-155. DOI: 10.1055/s-0034-1387632  1
2015 Draffin JE, Knafo S, Heneka MT. Alzheimer's Disease and Mechanism-Based Attempts to Enhance Cognition Cognitive Enhancement: Pharmacologic, Environmental and Genetic Factors. 193-231. DOI: 10.1016/B978-0-12-417042-1.00009-7  1
2015 Herrera-Rivero M, Heneka MT, Papadopoulos V. Translocator protein and new targets for neuroinflammation Clinical and Translational Imaging. 3: 391-402. DOI: 10.1007/s40336-015-0151-x  1
2015 Hong GS, Schwandt T, Stein K, Schneiker B, Kummer MP, Heneka MT, Kitamura K, Kalff JC, Wehner S. Effects of macrophage-dependent peroxisome proliferator-activated receptor γ signalling on adhesion formation after abdominal surgery in an experimental model British Journal of Surgery. DOI: 10.1002/bjs.9907  1
2014 Widmann CN, Schewe JC, Heneka MT. Sepsis-associated encephalopathy versus sepsis-induced encephalopathy--authors' reply. The Lancet. Neurology. 13: 968-9. PMID 25231518 DOI: 10.1016/S1474-4422(14)70204-2  1
2014 Heneka MT. Macrophages derived from infiltrating monocytes mediate autoimmune myelin destruction. The Journal of Experimental Medicine. 211: 1500. PMID 25071159 DOI: 10.1084/jem.2118insight1  1
2014 Thelen M, Razquin C, Hernández I, Gorostidi A, Sánchez-Valle R, Ortega-Cubero S, Wolfsgruber S, Drichel D, Fliessbach K, Duenkel T, Damian M, Heilmann S, Slotosch A, Lennarz M, Seijo-Martínez M, ... ... Heneka MT, et al. Investigation of the role of rare TREM2 variants in frontotemporal dementia subtypes. Neurobiology of Aging. 35: 2657.e13-9. PMID 25042114 DOI: 10.1016/j.neurobiolaging.2014.06.018  1
2014 Kummer MP, Heneka MT. Truncated and modified amyloid-beta species. Alzheimer's Research & Therapy. 6: 28. PMID 25031638 DOI: 10.1186/alzrt258  1
2014 Ramirez A, van der Flier WM, Herold C, Ramonet D, Heilmann S, Lewczuk P, Popp J, Lacour A, Drichel D, Louwersheimer E, Kummer MP, Cruchaga C, Hoffmann P, Teunissen C, Holstege H, ... ... Heneka MT, et al. SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease. Human Molecular Genetics. 23: 6644-58. PMID 25027320 DOI: 10.1093/hmg/ddu372  1
2014 Gockel I, Becker J, Wouters MM, Niebisch S, Gockel HR, Hess T, Ramonet D, Zimmermann J, Vigo AG, Trynka G, de León AR, de la Serna JP, Urcelay E, Kumar V, Franke L, ... ... Heneka MT, et al. Common variants in the HLA-DQ region confer susceptibility to idiopathic achalasia. Nature Genetics. 46: 901-4. PMID 24997987 DOI: 10.1038/ng.3029  1
2014 Kleinberger G, Yamanishi Y, Suárez-Calvet M, Czirr E, Lohmann E, Cuyvers E, Struyfs H, Pettkus N, Wenninger-Weinzierl A, Mazaheri F, Tahirovic S, Lleó A, Alcolea D, Fortea J, Willem M, ... ... Heneka MT, et al. TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis. Science Translational Medicine. 6: 243ra86. PMID 24990881 DOI: 10.1126/scitranslmed.3009093  1
2014 Kummer MP, Hammerschmidt T, Martinez A, Terwel D, Eichele G, Witten A, Figura S, Stoll M, Schwartz S, Pape HC, Schultze JL, Weinshenker D, Heneka MT, Urban I. Ear2 deletion causes early memory and learning deficits in APP/PS1 mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 8845-54. PMID 24966384 DOI: 10.1523/JNEUROSCI.4027-13.2014  1
2014 Heneka MT, Kummer MP, Latz E. Innate immune activation in neurodegenerative disease. Nature Reviews. Immunology. 14: 463-77. PMID 24962261 DOI: 10.1038/nri3705  1
2014 Krauthausen M, Saxe S, Zimmermann J, Emrich M, Heneka MT, Müller M. CXCR3 modulates glial accumulation and activation in cuprizone-induced demyelination of the central nervous system. Journal of Neuroinflammation. 11: 109. PMID 24930935 DOI: 10.1186/1742-2094-11-109  1
2014 van der Zee J, Van Langenhove T, Kovacs GG, Dillen L, Deschamps W, Engelborghs S, Mat?j R, Vandenbulcke M, Sieben A, Dermaut B, Smets K, Van Damme P, Merlin C, Laureys A, Van Den Broeck M, ... ... Heneka MT, et al. Rare mutations in SQSTM1 modify susceptibility to frontotemporal lobar degeneration. Acta Neuropathologica. 128: 397-410. PMID 24899140 DOI: 10.1007/s00401-014-1298-7  1
2014 Widmann CN, Heneka MT. Long-term cerebral consequences of sepsis. The Lancet. Neurology. 13: 630-6. PMID 24849863 DOI: 10.1016/S1474-4422(14)70017-1  1
2014 Brosseron F, Krauthausen M, Kummer M, Heneka MT. Body fluid cytokine levels in mild cognitive impairment and Alzheimer's disease: a comparative overview. Molecular Neurobiology. 50: 534-44. PMID 24567119 DOI: 10.1007/s12035-014-8657-1  1
2014 Peter J, Scheef L, Abdulkadir A, Boecker H, Heneka M, Wagner M, Koppara A, Klöppel S, Jessen F. Gray matter atrophy pattern in elderly with subjective memory impairment Alzheimer's and Dementia. 10: 99-108. PMID 23867795 DOI: 10.1016/j.jalz.2013.05.1764  1
2014 Malhotra A, Younesi E, Gündel M, Müller B, Heneka MT, Hofmann-Apitius M. ADO: a disease ontology representing the domain knowledge specific to Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 10: 238-46. PMID 23830913 DOI: 10.1016/j.jalz.2013.02.009  1
2013 Gaikwad SM, Heneka MT. Studying M1 and M2 states in adult microglia. Methods in Molecular Biology (Clifton, N.J.). 1041: 185-97. PMID 23813380 DOI: 10.1007/978-1-62703-520-0_18  1
2013 Chalermpalanupap T, Kinkead B, Hu WT, Kummer MP, Hammerschmidt T, Heneka MT, Weinshenker D, Levey AI. Targeting norepinephrine in mild cognitive impairment and Alzheimer's disease. Alzheimer's Research & Therapy. 5: 21. PMID 23634965 DOI: 10.1186/alzrt175  1
2013 Molinuevo JL, Gispert JD, Dubois B, Heneka MT, Lleo A, Engelborghs S, Pujol J, de Souza LC, Alcolea D, Jessen F, Sarazin M, Lamari F, Balasa M, Antonell A, Rami L. The AD-CSF-index discriminates Alzheimer's disease patients from healthy controls: a validation study. Journal of Alzheimer's Disease : Jad. 36: 67-77. PMID 23524657 DOI: 10.3233/JAD-130203  1
2013 Zimmermann J, Krauthausen M, Hofer MJ, Heneka MT, Campbell IL, Müller M. CNS-targeted production of IL-17A induces glial activation, microvascular pathology and enhances the neuroinflammatory response to systemic endotoxemia. Plos One. 8: e57307. PMID 23468966 DOI: 10.1371/journal.pone.0057307  1
2013 Okroglic S, Widmann CN, Urbach H, Scheltens P, Heneka MT. Clinical symptoms and risk factors in cerebral microangiopathy patients. Plos One. 8: e53455. PMID 23393549 DOI: 10.1371/journal.pone.0053455  1
2013 Heneka MT, Kummer MP, Stutz A, Delekate A, Schwartz S, Vieira-Saecker A, Griep A, Axt D, Remus A, Tzeng TC, Gelpi E, Halle A, Korte M, Latz E, Golenbock DT. NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice. Nature. 493: 674-8. PMID 23254930 DOI: 10.1038/nature11729  1
2013 Semmler A, Widmann CN, Okulla T, Urbach H, Kaiser M, Widman G, Mormann F, Weide J, Fliessbach K, Hoeft A, Jessen F, Putensen C, Heneka MT. Persistent cognitive impairment, hippocampal atrophy and EEG changes in sepsis survivors. Journal of Neurology, Neurosurgery, and Psychiatry. 84: 62-9. PMID 23134661 DOI: 10.1136/jnnp-2012-302883  1
2013 van der Zee J, Gijselinck I, Dillen L, Van Langenhove T, Theuns J, Engelborghs S, Philtjens S, Vandenbulcke M, Sleegers K, Sieben A, Bäumer V, Maes G, Corsmit E, Borroni B, Padovani A, ... ... Heneka MT, ... ... Heneka MT, ... ... Heneka MT, et al. A pan-European study of the C9orf72 repeat associated with FTLD: geographic prevalence, genomic instability, and intermediate repeats. Human Mutation. 34: 363-73. PMID 23111906 DOI: 10.1002/humu.22244  1
2013 Hammerschmidt T, Kummer MP, Terwel D, Martinez A, Gorji A, Pape HC, Rommelfanger KS, Schroeder JP, Stoll M, Schultze J, Weinshenker D, Heneka MT. Selective loss of noradrenaline exacerbates early cognitive dysfunction and synaptic deficits in APP/PS1 mice. Biological Psychiatry. 73: 454-63. PMID 22883210 DOI: 10.1016/j.biopsych.2012.06.013  1
2013 Semmler A, Okulla T, Kaiser M, Seifert B, Heneka MT. Long-term neuromuscular sequelae of critical illness. Journal of Neurology. 260: 151-7. PMID 22820684 DOI: 10.1007/s00415-012-6605-4  1
2013 Rapic S, Backes H, Viel T, Kummer MP, Monfared P, Neumaier B, Vollmar S, Hoehn M, Van der Linden A, Heneka MT, Jacobs AH. Imaging microglial activation and glucose consumption in a mouse model of Alzheimer's disease. Neurobiology of Aging. 34: 351-4. PMID 22651996 DOI: 10.1016/j.neurobiolaging.2012.04.016  1
2012 Kummer MP, Vogl T, Axt D, Griep A, Vieira-Saecker A, Jessen F, Gelpi E, Roth J, Heneka MT. Mrp14 deficiency ameliorates amyloid β burden by increasing microglial phagocytosis and modulation of amyloid precursor protein processing. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17824-9. PMID 23223301 DOI: 10.1523/JNEUROSCI.1504-12.2012  1
2012 Yamanaka M, Ishikawa T, Griep A, Axt D, Kummer MP, Heneka MT. PPARγ/RXRα-induced and CD36-mediated microglial amyloid-β phagocytosis results in cognitive improvement in amyloid precursor protein/presenilin 1 mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 17321-31. PMID 23197723 DOI: 10.1523/JNEUROSCI.1569-12.2012  1
2012 Scheef L, Spottke A, Daerr M, Joe A, Striepens N, Kölsch H, Popp J, Daamen M, Gorris D, Heneka MT, Boecker H, Biersack HJ, Maier W, Schild HH, Wagner M, et al. Glucose metabolism, gray matter structure, and memory decline in subjective memory impairment. Neurology. 79: 1332-9. PMID 22914828 DOI: 10.1212/WNL.0b013e31826c1a8d  1
2012 Dupuis L, Dengler R, Heneka MT, Meyer T, Zierz S, Kassubek J, Fischer W, Steiner F, Lindauer E, Otto M, Dreyhaupt J, Grehl T, Hermann A, Winkler AS, Bogdahn U, et al. A randomized, double blind, placebo-controlled trial of pioglitazone in combination with riluzole in amyotrophic lateral sclerosis. Plos One. 7: e37885. PMID 22715372 DOI: 10.1371/journal.pone.0037885  1
2012 Parpura V, Heneka MT, Montana V, Oliet SH, Schousboe A, Haydon PG, Stout RF, Spray DC, Reichenbach A, Pannicke T, Pekny M, Pekna M, Zorec R, Verkhratsky A. Glial cells in (patho)physiology. Journal of Neurochemistry. 121: 4-27. PMID 22251135 DOI: 10.1111/j.1471-4159.2012.07664.x  1
2012 Kummer MP, Hülsmann C, Hermes M, Axt D, Heneka MT. Nitric oxide decreases the enzymatic activity of insulin degrading enzyme in APP/PS1 mice. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 7: 165-72. PMID 22227962 DOI: 10.1007/s11481-011-9339-7  1
2012 Liu S, Liu Y, Hao W, Wolf L, Kiliaan AJ, Penke B, Rübe CE, Walter J, Heneka MT, Hartmann T, Menger MD, Fassbender K. TLR2 is a primary receptor for Alzheimer's amyloid β peptide to trigger neuroinflammatory activation. Journal of Immunology (Baltimore, Md. : 1950). 188: 1098-107. PMID 22198949 DOI: 10.4049/jimmunol.1101121  1
2012 Rey NL, Jardanhazi-Kurutz D, Terwel D, Kummer MP, Jourdan F, Didier A, Heneka MT. Locus coeruleus degeneration exacerbates olfactory deficits in APP/PS1 transgenic mice. Neurobiology of Aging. 33: 426.e1-11. PMID 21109328 DOI: 10.1016/j.neurobiolaging.2010.10.009  1
2011 Heneka MT, Reyes-Irisarri E, Hüll M, Kummer MP. Impact and Therapeutic Potential of PPARs in Alzheimer's Disease. Current Neuropharmacology. 9: 643-50. PMID 22654722 DOI: 10.2174/157015911798376325  1
2011 Krauthausen M, Ellis SL, Zimmermann J, Sarris M, Wakefield D, Heneka MT, Campbell IL, Müller M. Opposing roles for CXCR3 signaling in central nervous system versus ocular inflammation mediated by the astrocyte-targeted production of IL-12. The American Journal of Pathology. 179: 2346-59. PMID 21925471 DOI: 10.1016/j.ajpath.2011.07.041  1
2011 Kummer MP, Hermes M, Delekarte A, Hammerschmidt T, Kumar S, Terwel D, Walter J, Pape HC, König S, Roeber S, Jessen F, Klockgether T, Korte M, Heneka MT. Nitration of tyrosine 10 critically enhances amyloid β aggregation and plaque formation. Neuron. 71: 833-44. PMID 21903077 DOI: 10.1016/j.neuron.2011.07.001  1
2011 Mildner A, Schlevogt B, Kierdorf K, Böttcher C, Erny D, Kummer MP, Quinn M, Brück W, Bechmann I, Heneka MT, Priller J, Prinz M. Distinct and non-redundant roles of microglia and myeloid subsets in mouse models of Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 11159-71. PMID 21813677 DOI: 10.1523/JNEUROSCI.6209-10.2011  1
2011 Mattsson N, Andreasson U, Persson S, Arai H, Batish SD, Bernardini S, Bocchio-Chiavetto L, Blankenstein MA, Carrillo MC, Chalbot S, Coart E, Chiasserini D, Cutler N, Dahlfors G, Duller S, ... ... Heneka MT, et al. The Alzheimer's Association external quality control program for cerebrospinal fluid biomarkers. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 7: 386-395.e6. PMID 21784349 DOI: 10.1016/j.jalz.2011.05.2243  1
2011 Juckel G, Manitz MP, Brüne M, Friebe A, Heneka MT, Wolf RJ. Microglial activation in a neuroinflammational animal model of schizophrenia--a pilot study. Schizophrenia Research. 131: 96-100. PMID 21752601 DOI: 10.1016/j.schres.2011.06.018  1
2011 Terwel D, Steffensen KR, Verghese PB, Kummer MP, Gustafsson JÅ, Holtzman DM, Heneka MT. Critical role of astroglial apolipoprotein E and liver X receptor-α expression for microglial Aβ phagocytosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7049-59. PMID 21562267 DOI: 10.1523/JNEUROSCI.6546-10.2011  1
2011 Kumar S, Rezaei-Ghaleh N, Terwel D, Thal DR, Richard M, Hoch M, Mc Donald JM, Wüllner U, Glebov K, Heneka MT, Walsh DM, Zweckstetter M, Walter J. Extracellular phosphorylation of the amyloid β-peptide promotes formation of toxic aggregates during the pathogenesis of Alzheimer's disease. The Embo Journal. 30: 2255-65. PMID 21527912 DOI: 10.1038/emboj.2011.138  1
2011 Terwel D, Löschmann YN, Schmidt HH, Schöler HR, Cantz T, Heneka MT. Neuroinflammatory and behavioural changes in the Atp7B mutant mouse model of Wilson's disease. Journal of Neurochemistry. 118: 105-12. PMID 21517843 DOI: 10.1111/j.1471-4159.2011.07278.x  1
2011 Heneka MT, Kummer MP, Weggen S, Bulic B, Multhaup G, Münter L, Hüll M, Pflanzner T, Pietrzik CU. Molecular mechanisms and therapeutic application of NSAIDs and derived compounds in Alzheimer's disease. Current Alzheimer Research. 8: 115-31. PMID 21345168  1
2011 Jardanhazi-Kurutz D, Kummer MP, Terwel D, Vogel K, Thiele A, Heneka MT. Distinct adrenergic system changes and neuroinflammation in response to induced locus ceruleus degeneration in APP/PS1 transgenic mice. Neuroscience. 176: 396-407. PMID 21129451 DOI: 10.1016/j.neuroscience.2010.11.052  1
2011 Perez Nievas BG, Hammerschmidt T, Kummer MP, Terwel D, Leza JC, Heneka MT. Restraint stress increases neuroinflammation independently of amyloid β levels in amyloid precursor protein/PS1 transgenic mice. Journal of Neurochemistry. 116: 43-52. PMID 21044080 DOI: 10.1111/j.1471-4159.2010.07083.x  1
2011 Gaikwad SM, Widmann CN, Heneka MT. Sepsis–induced neuronal dysfunction and death Brain Disorders in Critical Illness: Mechanisms, Diagnosis, and Treatment. 200-207. DOI: 10.1017/CBO9781139248822.024  1
2010 Fleisher-Berkovich S, Filipovich-Rimon T, Ben-Shmuel S, Hülsmann C, Kummer MP, Heneka MT. Distinct modulation of microglial amyloid β phagocytosis and migration by neuropeptides (i). Journal of Neuroinflammation. 7: 61. PMID 20937084 DOI: 10.1186/1742-2094-7-61  1
2010 Tamboli IY, Barth E, Christian L, Siepmann M, Kumar S, Singh S, Tolksdorf K, Heneka MT, Lütjohann D, Wunderlich P, Walter J. Statins promote the degradation of extracellular amyloid {beta}-peptide by microglia via stimulation of exosome-associated insulin-degrading enzyme (IDE) secretion. The Journal of Biological Chemistry. 285: 37405-14. PMID 20876579 DOI: 10.1074/jbc.M110.149468  1
2010 Heneka MT, O'Banion MK, Terwel D, Kummer MP. Neuroinflammatory processes in Alzheimer's disease. Journal of Neural Transmission (Vienna, Austria : 1996). 117: 919-47. PMID 20632195 DOI: 10.1007/s00702-010-0438-z  1
2010 Heneka MT. [Course modifying therapy of Alzheimer's dementia]. Der Nervenarzt. 81: 807-8, 810-4. PMID 20567962 DOI: 10.1007/s00115-010-3000-1  1
2010 Heneka MT, Nadrigny F, Regen T, Martinez-Hernandez A, Dumitrescu-Ozimek L, Terwel D, Jardanhazi-Kurutz D, Walter J, Kirchhoff F, Hanisch UK, Kummer MP. Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine. Proceedings of the National Academy of Sciences of the United States of America. 107: 6058-63. PMID 20231476 DOI: 10.1073/pnas.0909586107  1
2010 Jardanhazi-Kurutz D, Kummer MP, Terwel D, Vogel K, Dyrks T, Thiele A, Heneka MT. Induced LC degeneration in APP/PS1 transgenic mice accelerates early cerebral amyloidosis and cognitive deficits. Neurochemistry International. 57: 375-82. PMID 20144675 DOI: 10.1016/j.neuint.2010.02.001  1
2010 Schlachetzki JC, Fiebich BL, Haake E, de Oliveira AC, Candelario-Jalil E, Heneka MT, Hüll M. Norepinephrine enhances the LPS-induced expression of COX-2 and secretion of PGE2 in primary rat microglia. Journal of Neuroinflammation. 7: 2. PMID 20064241 DOI: 10.1186/1742-2094-7-2  1
2010 Heneka MT, Rodríguez JJ, Verkhratsky A. Neuroglia in neurodegeneration. Brain Research Reviews. 63: 189-211. PMID 19944719 DOI: 10.1016/j.brainresrev.2009.11.004  1
2009 Weberpals M, Hermes M, Hermann S, Kummer MP, Terwel D, Semmler A, Berger M, Schäfers M, Heneka MT. NOS2 gene deficiency protects from sepsis-induced long-term cognitive deficits. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 14177-84. PMID 19906966 DOI: 10.1523/JNEUROSCI.3238-09.2009  1
2009 Jäger S, Leuchtenberger S, Martin A, Czirr E, Wesselowski J, Dieckmann M, Waldron E, Korth C, Koo EH, Heneka M, Weggen S, Pietrzik CU. alpha-secretase mediated conversion of the amyloid precursor protein derived membrane stub C99 to C83 limits Abeta generation. Journal of Neurochemistry. 111: 1369-82. PMID 19804379 DOI: 10.1111/j.1471-4159.2009.06420.x  1
2009 Papi A, Tatenhorst L, Terwel D, Hermes M, Kummer MP, Orlandi M, Heneka MT. PPARgamma and RXRgamma ligands act synergistically as potent antineoplastic agents in vitro and in vivo glioma models. Journal of Neurochemistry. 109: 1779-90. PMID 19457135 DOI: 10.1111/j.1471-4159.2009.06111.x  1
2009 Heneka MT. Noradrenergic denervation facilitates the release of acetylcholine and serotonin in the hippocampus: towards a mechanism underlying upregulations described in MCI patients. Experimental Neurology. 217: 237-9. PMID 19328200 DOI: 10.1016/j.expneurol.2009.03.013  1
2008 Tamboli IY, Prager K, Thal DR, Thelen KM, Dewachter I, Pietrzik CU, St George-Hyslop P, Sisodia SS, De Strooper B, Heneka MT, Filippov MA, Müller U, van Leuven F, Lütjohann D, Walter J. Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 12097-106. PMID 19005074 DOI: 10.1523/JNEUROSCI.2635-08.2008  1
2008 Seufert S, Coras R, Tränkle C, Zlotos DP, Blümcke I, Tatenhorst L, Heneka MT, Hahnen E. PPAR Gamma Activators: Off-Target Against Glioma Cell Migration and Brain Invasion. Ppar Research. 2008: 513943. PMID 18815619 DOI: 10.1155/2008/513943  1
2008 Semmler A, Hermann S, Mormann F, Weberpals M, Paxian SA, Okulla T, Schäfers M, Kummer MP, Klockgether T, Heneka MT. Sepsis causes neuroinflammation and concomitant decrease of cerebral metabolism. Journal of Neuroinflammation. 5: 38. PMID 18793399 DOI: 10.1186/1742-2094-5-38  1
2008 Kummer MP, Heneka MT. PPARs in Alzheimer's Disease. Ppar Research. 2008: 403896. PMID 18645613 DOI: 10.1155/2008/403896  1
2008 Landreth G, Jiang Q, Mandrekar S, Heneka M. PPARgamma agonists as therapeutics for the treatment of Alzheimer's disease. Neurotherapeutics : the Journal of the American Society For Experimental Neurotherapeutics. 5: 481-9. PMID 18625459 DOI: 10.1016/j.nurt.2008.05.003  1
2008 Winkeler A, Waerzeggers Y, Klose A, Monfared P, Thomas AV, Schubert M, Heneka MT, Jacobs AH. Imaging noradrenergic influence on amyloid pathology in mouse models of Alzheimer's disease. European Journal of Nuclear Medicine and Molecular Imaging. 35: S107-13. PMID 18219484 DOI: 10.1007/s00259-007-0710-0  1
2008 Jiang Q, Heneka M, Landreth GE. The role of peroxisome proliferator-activated receptor-gamma (PPARgamma) in Alzheimer's disease: therapeutic implications. Cns Drugs. 22: 1-14. PMID 18072811  1
2007 Thees C, Kaiser M, Scholz M, Semmler A, Heneka MT, Baumgarten G, Hoeft A, Putensen C. Cerebral haemodynamics and carbon dioxide reactivity during sepsis syndrome. Critical Care (London, England). 11: R123. PMID 18045492 DOI: 10.1186/cc6185  1
2007 Heneka MT, Landreth GE, Hüll M. Drug insight: effects mediated by peroxisome proliferator-activated receptor-gamma in CNS disorders. Nature Clinical Practice. Neurology. 3: 496-504. PMID 17805244 DOI: 10.1038/ncpneuro0586  1
2007 Heneka MT, Landreth GE. PPARs in the brain. Biochimica Et Biophysica Acta. 1771: 1031-45. PMID 17569578 DOI: 10.1016/j.bbalip.2007.04.016  1
2007 Winkeler A, Sena-Esteves M, Paulis LE, Li H, Waerzeggers Y, Rückriem B, Himmelreich U, Klein M, Monfared P, Rueger MA, Heneka M, Vollmar S, Hoehn M, Fraefel C, Graf R, et al. Switching on the lights for gene therapy. Plos One. 2: e528. PMID 17565381 DOI: 10.1371/journal.pone.0000528  1
2007 Kummer C, Winkeler A, Dittmar C, Bauer B, Rueger MA, Rueckriem B, Heneka MT, Vollmar S, Wienhard K, Fraefel C, Heiss WD, Jacobs AH. Multitracer positron emission tomographic imaging of exogenous gene expression mediated by a universal herpes simplex virus 1 amplicon vector. Molecular Imaging. 6: 181-92. PMID 17532884 DOI: 10.2310/7290.2007.00015  1
2007 Rueger MA, Kracht LW, Hilker R, Thiel A, Sobesky J, Winkeler A, Thomas AV, Heneka MT, Graf R, Herholz K, Heiss WD, Jacobs AH. Role of in vivo imaging of the central nervous system for developing novel drugs. The Quarterly Journal of Nuclear Medicine and Molecular Imaging : Official Publication of the Italian Association of Nuclear Medicine (Aimn) [and] the International Association of Radiopharmacology (Iar), [and] Section of the Society of Radiopharmaceutical Chemistry and Biology. 51: 164-81. PMID 17420717  1
2007 Jacobs AH, Rueger MA, Winkeler A, Li H, Vollmar S, Waerzeggers Y, Rueckriem B, Kummer C, Dittmar C, Klein M, Heneka MT, Herrlinger U, Fraefel C, Graf R, Wienhard K, et al. Imaging-guided gene therapy of experimental gliomas. Cancer Research. 67: 1706-15. PMID 17308112 DOI: 10.1158/0008-5472.CAN-06-2418  1
2007 Semmler A, Frisch C, Debeir T, Ramanathan M, Okulla T, Klockgether T, Heneka MT. Long-term cognitive impairment, neuronal loss and reduced cortical cholinergic innervation after recovery from sepsis in a rodent model. Experimental Neurology. 204: 733-40. PMID 17306796 DOI: 10.1016/j.expneurol.2007.01.003  1
2007 Heneka MT, O'Banion MK. Inflammatory processes in Alzheimer's disease. Journal of Neuroimmunology. 184: 69-91. PMID 17222916 DOI: 10.1016/j.jneuroim.2006.11.017  1
2007 Kalinin S, Gavrilyuk V, Polak PE, Vasser R, Zhao J, Heneka MT, Feinstein DL. Noradrenaline deficiency in brain increases beta-amyloid plaque burden in an animal model of Alzheimer's disease. Neurobiology of Aging. 28: 1206-14. PMID 16837104 DOI: 10.1016/j.neurobiolaging.2006.06.003  1
2006 Wahle T, Thal DR, Sastre M, Rentmeister A, Bogdanovic N, Famulok M, Heneka MT, Walter J. GGA1 is expressed in the human brain and affects the generation of amyloid beta-peptide. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 12838-46. PMID 17151287 DOI: 10.1523/JNEUROSCI.1982-06.2006  1
2006 Hüll M, Berger M, Heneka M. Disease-modifying therapies in Alzheimer's disease: how far have we come? Drugs. 66: 2075-93. PMID 17112302 DOI: 10.2165/00003495-200666160-00004  1
2006 Grommes C, Landreth GE, Sastre M, Beck M, Feinstein DL, Jacobs AH, Schlegel U, Heneka MT. Inhibition of in vivo glioma growth and invasion by peroxisome proliferator-activated receptor gamma agonist treatment. Molecular Pharmacology. 70: 1524-33. PMID 16887936 DOI: 10.1124/mol.106.022194  1
2006 Ambrée O, Leimer U, Herring A, Görtz N, Sachser N, Heneka MT, Paulus W, Keyvani K. Reduction of amyloid angiopathy and Abeta plaque burden after enriched housing in TgCRND8 mice: involvement of multiple pathways. The American Journal of Pathology. 169: 544-52. PMID 16877355 DOI: 10.2353/ajpath.2006.051107  1
2006 Sastre M, Klockgether T, Heneka MT. Contribution of inflammatory processes to Alzheimer's disease: molecular mechanisms. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 24: 167-76. PMID 16472958 DOI: 10.1016/j.ijdevneu.2005.11.014  1
2006 Heneka MT, Ramanathan M, Jacobs AH, Dumitrescu-Ozimek L, Bilkei-Gorzo A, Debeir T, Sastre M, Galldiks N, Zimmer A, Hoehn M, Heiss WD, Klockgether T, Staufenbiel M. Locus ceruleus degeneration promotes Alzheimer pathogenesis in amyloid precursor protein 23 transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 1343-54. PMID 16452658 DOI: 10.1523/JNEUROSCI.4236-05.2006  1
2006 Sastre M, Dewachter I, Rossner S, Bogdanovic N, Rosen E, Borghgraef P, Evert BO, Dumitrescu-Ozimek L, Thal DR, Landreth G, Walter J, Klockgether T, van Leuven F, Heneka MT. Nonsteroidal anti-inflammatory drugs repress beta-secretase gene promoter activity by the activation of PPARgamma. Proceedings of the National Academy of Sciences of the United States of America. 103: 443-8. PMID 16407166 DOI: 10.1073/pnas.0503839103  1
2006 Heneka MT. Inflammation in Alzheimer's disease Clinical Neuroscience Research. 6: 247-260. DOI: 10.1016/j.cnr.2006.09.005  1
2006 Tamboli IY, Prager K, Barth E, Heneka M, Sandhoff K, Walter J. Modulation of proteolytic processing by glycosphingolipids generates amyloid β-peptide Sphingolipid Biology. 319-328. DOI: 10.1007/4-431-34200-1_25  1
2005 Heneka MT, Sastre M, Dumitrescu-Ozimek L, Dewachter I, Walter J, Klockgether T, Van Leuven F. Focal glial activation coincides with increased BACE1 activation and precedes amyloid plaque deposition in APP[V717I] transgenic mice. Journal of Neuroinflammation. 2: 22. PMID 16212664 DOI: 10.1186/1742-2094-2-22  1
2005 Klotz L, Schmidt M, Giese T, Sastre M, Knolle P, Klockgether T, Heneka MT. Proinflammatory stimulation and pioglitazone treatment regulate peroxisome proliferator-activated receptor gamma levels in peripheral blood mononuclear cells from healthy controls and multiple sclerosis patients. Journal of Immunology (Baltimore, Md. : 1950). 175: 4948-55. PMID 16210596  1
2005 Semmler A, Okulla T, Sastre M, Dumitrescu-Ozimek L, Heneka MT. Systemic inflammation induces apoptosis with variable vulnerability of different brain regions. Journal of Chemical Neuroanatomy. 30: 144-57. PMID 16122904 DOI: 10.1016/j.jchemneu.2005.07.003  1
2005 Schütz B, Reimann J, Dumitrescu-Ozimek L, Kappes-Horn K, Landreth GE, Schürmann B, Zimmer A, Heneka MT. The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 7805-12. PMID 16120782 DOI: 10.1523/JNEUROSCI.2038-05.2005  1
2005 Heneka MT, Sastre M, Dumitrescu-Ozimek L, Hanke A, Dewachter I, Kuiperi C, O'Banion K, Klockgether T, Van Leuven F, Landreth GE. Acute treatment with the PPARgamma agonist pioglitazone and ibuprofen reduces glial inflammation and Abeta1-42 levels in APPV717I transgenic mice. Brain : a Journal of Neurology. 128: 1442-53. PMID 15817521 DOI: 10.1093/brain/awh452  1
2005 Rueger MA, Winkeler A, Miletic H, Kaestle C, Richter R, Schneider G, Hilker R, Heneka MT, Ernestus RI, Hampl JA, Fraefel C, Jacobs AH. Variability in infectivity of primary cell cultures of human brain tumors with HSV-1 amplicon vectors. Gene Therapy. 12: 588-96. PMID 15674397 DOI: 10.1038/sj.gt.3302462  1
2005 Grommes C, Landreth GE, Schlegel U, Heneka MT. The nonthiazolidinedione tyrosine-based peroxisome proliferator-activated receptor gamma ligand GW7845 induces apoptosis and limits migration and invasion of rat and human glioma cells. The Journal of Pharmacology and Experimental Therapeutics. 313: 806-13. PMID 15665144 DOI: 10.1124/jpet.104.078972  1
2004 Lacombe P, Mathews PM, Schmidt SD, Breidert T, Heneka MT, Landreth GE, Feinstein DL, Galea E. Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revised. Journal of Neuroinflammation. 1: 11. PMID 15285804 DOI: 10.1186/1742-2094-1-11  1
2004 Pershadsingh HA, Heneka MT, Saini R, Amin NM, Broeske DJ, Feinstein DL. Effect of pioglitazone treatment in a patient with secondary multiple sclerosis. Journal of Neuroinflammation. 1: 3. PMID 15285799 DOI: 10.1186/1742-2094-1-3  1
2004 Grommes C, Landreth GE, Heneka MT. Antineoplastic effects of peroxisome proliferator-activated receptor gamma agonists. The Lancet. Oncology. 5: 419-29. PMID 15231248 DOI: 10.1016/S1470-2045(04)01509-8  1
2004 Dehmer T, Heneka MT, Sastre M, Dichgans J, Schulz JB. Protection by pioglitazone in the MPTP model of Parkinson's disease correlates with I kappa B alpha induction and block of NF kappa B and iNOS activation. Journal of Neurochemistry. 88: 494-501. PMID 14690537  1
2004 Schmidt S, Moric E, Schmidt M, Sastre M, Feinstein DL, Heneka MT. Anti-inflammatory and antiproliferative actions of PPAR-gamma agonists on T lymphocytes derived from MS patients. Journal of Leukocyte Biology. 75: 478-85. PMID 14657213 DOI: 10.1189/jlb.0803402  1
2003 Pedraza CE, Baltrons MA, Heneka MT, García A. Interleukin-1 beta and lipopolysaccharide decrease soluble guanylyl cyclase in brain cells: NO-independent destabilization of protein and NO-dependent decrease of mRNA. Journal of Neuroimmunology. 144: 80-90. PMID 14597101 DOI: 10.1016/j.jneuroim.2003.08.034  1
2003 Sastre M, Dewachter I, Landreth GE, Willson TM, Klockgether T, van Leuven F, Heneka MT. Nonsteroidal anti-inflammatory drugs and peroxisome proliferator-activated receptor-gamma agonists modulate immunostimulated processing of amyloid precursor protein through regulation of beta-secretase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 23: 9796-804. PMID 14586007  1
2003 Galea E, Heneka MT, Dello Russo C, Feinstein DL. Intrinsic regulation of brain inflammatory responses. Cellular and Molecular Neurobiology. 23: 625-35. PMID 14514020 DOI: 10.1023/A:1025084415833  1
2003 Klotz L, Sastre M, Kreutz A, Gavrilyuk V, Klockgether T, Feinstein DL, Heneka MT. Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARgamma) in murine primary astrocytes and neurons. Journal of Neurochemistry. 86: 907-16. PMID 12887689 DOI: 10.1046/j.1471-4159.2003.01909.x  1
2003 Harzheim M, Altenschmidt M, Heneka MT, Schröder R, Klockgether T, Schmidt S. IFN-beta1a (Rebif) modifies the expression of microfilament-associated cell-cell contacts in C6 glioma cells. Journal of Interferon & Cytokine Research : the Official Journal of the International Society For Interferon and Cytokine Research. 23: 83-9. PMID 12744773 DOI: 10.1089/107999003321455471  1
2003 Heneka MT, Gavrilyuk V, Landreth GE, O'Banion MK, Weinberg G, Feinstein DL. Noradrenergic depletion increases inflammatory responses in brain: effects on IkappaB and HSP70 expression. Journal of Neurochemistry. 85: 387-98. PMID 12675915  1
2002 Feinstein DL, Heneka MT, Gavrilyuk V, Dello Russo C, Weinberg G, Galea E. Noradrenergic regulation of inflammatory gene expression in brain. Neurochemistry International. 41: 357-65. PMID 12176079 DOI: 10.1016/S0197-0186(02)00049-9  1
2002 Breidert T, Callebert J, Heneka MT, Landreth G, Launay JM, Hirsch EC. Protective action of the peroxisome proliferator-activated receptor-gamma agonist pioglitazone in a mouse model of Parkinson's disease. Journal of Neurochemistry. 82: 615-24. PMID 12153485 DOI: 10.1046/j.1471-4159.2002.00990.x  1
2002 Baltrons MA, Pedraza CE, Heneka MT, García A. Beta-amyloid peptides decrease soluble guanylyl cyclase expression in astroglial cells. Neurobiology of Disease. 10: 139-49. PMID 12127152 DOI: 10.1006/nbdi.2002.0492  1
2002 Feinstein DL, Galea E, Gavrilyuk V, Brosnan CF, Whitacre CC, Dumitrescu-Ozimek L, Landreth GE, Pershadsingh HA, Weinberg G, Heneka MT. Peroxisome proliferator-activated receptor-gamma agonists prevent experimental autoimmune encephalomyelitis. Annals of Neurology. 51: 694-702. PMID 12112074 DOI: 10.1002/ana.10206  1
2002 Zander T, Kraus JA, Grommes C, Schlegel U, Feinstein D, Klockgether T, Landreth G, Koenigsknecht J, Heneka MT. Induction of apoptosis in human and rat glioma by agonists of the nuclear receptor PPARgamma. Journal of Neurochemistry. 81: 1052-60. PMID 12065618 DOI: 10.1046/j.1471-4159.2002.00899.x  1
2002 Gavrilyuk V, Dello Russo C, Heneka MT, Pelligrino D, Weinberg G, Feinstein DL. Norepinephrine increases I kappa B alpha expression in astrocytes. The Journal of Biological Chemistry. 277: 29662-8. PMID 12050158 DOI: 10.1074/jbc.M203256200  1
2002 Heneka MT, Galea E, Gavriluyk V, Dumitrescu-Ozimek L, Daeschner J, O'Banion MK, Weinberg G, Klockgether T, Feinstein DL. Noradrenergic depletion potentiates beta -amyloid-induced cortical inflammation: implications for Alzheimer's disease. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 2434-42. PMID 11923407  1
2002 Murphy P, Sharp A, Shin J, Gavrilyuk V, Dello Russo C, Weinberg G, Sharp FR, Lu A, Heneka MT, Feinstein DL. Suppressive effects of ansamycins on inducible nitric oxide synthase expression and the development of experimental autoimmune encephalomyelitis. Journal of Neuroscience Research. 67: 461-70. PMID 11835313 DOI: 10.1002/jnr.10139  1
2001 Landreth GE, Heneka MT. Anti-inflammatory actions of peroxisome proliferator-activated receptor gamma agonists in Alzheimer's disease. Neurobiology of Aging. 22: 937-44. PMID 11755002 DOI: 10.1016/S0197-4580(01)00296-2  1
2001 Heneka MT, Wiesinger H, Dumitrescu-Ozimek L, Riederer P, Feinstein DL, Klockgether T. Neuronal and glial coexpression of argininosuccinate synthetase and inducible nitric oxide synthase in Alzheimer disease. Journal of Neuropathology and Experimental Neurology. 60: 906-16. PMID 11556547  1
2001 Heneka MT, Sharp A, Murphy P, Lyons JA, Dumitrescu L, Feinstein DL. The heat shock response reduces myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in mice. Journal of Neurochemistry. 77: 568-79. PMID 11299319 DOI: 10.1046/j.1471-4159.2001.00260.x  1
2001 Heneka MT, Feinstein DL. Expression and function of inducible nitric oxide synthase in neurons. Journal of Neuroimmunology. 114: 8-18. PMID 11240010 DOI: 10.1016/S0165-5728(01)00246-6  1
2001 Heneka MT, Landreth GE, Feinstein DL. Role for peroxisome proliferator-activated receptor-gamma in Alzheimer's disease. Annals of Neurology. 49: 276. PMID 11220752  1
2000 Heneka MT, Klockgether T, Feinstein DL. Peroxisome proliferator-activated receptor-gamma ligands reduce neuronal inducible nitric oxide synthase expression and cell death in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 6862-7. PMID 10995830  1
2000 Heneka MT, Sharp A, Klockgether T, Gavrilyuk V, Feinstein DL. The heat shock response inhibits NF-kappaB activation, nitric oxide synthase type 2 expression, and macrophage/microglial activation in brain. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 20: 800-11. PMID 10826530 DOI: 10.1097/00004647-200005000-00006  1
2000 Heneka MT, Dumitrescu L, Löschmann PA, Wüllner U, Klockgether T. Temporal, regional, and cell-specific changes of iNOS expression after intrastriatal microinjection of interferon gamma and bacterial lipopolysaccharide. Journal of Chemical Neuroanatomy. 18: 167-79. PMID 10781735 DOI: 10.1016/S0891-0618(00)00041-7  1
1999 Heneka MT, Feinstein DL, Galea E, Gleichmann M, Wüllner U, Klockgether T. Peroxisome proliferator-activated receptor gamma agonists protect cerebellar granule cells from cytokine-induced apoptotic cell death by inhibition of inducible nitric oxide synthase. Journal of Neuroimmunology. 100: 156-68. PMID 10695726 DOI: 10.1016/S0165-5728(99)00192-7  1
1999 Heneka MT, Schmidlin A, Wiesinger H. Induction of argininosuccinate synthetase in rat brain glial cells after striatal microinjection of immunostimulants. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 19: 898-907. PMID 10458597 DOI: 10.1097/00004647-199908000-00009  1
1998 Schulz JB, Weller M, Matthews RT, Heneka MT, Groscurth P, Martinou JC, Lommatzsch J, von Coelln R, Wüllner U, Löschmann PA, Beal MF, Dichgans J, Klockgether T. Extended therapeutic window for caspase inhibition and synergy with MK-801 in the treatment of cerebral histotoxic hypoxia. Cell Death and Differentiation. 5: 847-57. PMID 10203688 DOI: 10.1038/sj.cdd.4400420  1
1998 Heneka MT, Löschmann PA, Gleichmann M, Weller M, Schulz JB, Wüllner U, Klockgether T. Induction of nitric oxide synthase and nitric oxide-mediated apoptosis in neuronal PC12 cells after stimulation with tumor necrosis factor-alpha/lipopolysaccharide. Journal of Neurochemistry. 71: 88-94. PMID 9648854  1
1997 Löschmann PA, Wüllner U, Heneka MT, Schulz JB, Kunow M, Wachtel H, Klockgether T. Differential interaction of competitive NMDA and AMPA antagonists with selective dopamine D-1 and D-2 agonists in a rat model of Parkinson's disease. Synapse (New York, N.Y.). 26: 381-91. PMID 9215597 DOI: 10.1002/(SICI)1098-2396(199708)26:4<381::AID-SYN6>3.0.CO;2-2  1
1997 Heneka MT, Löschmann PA, Osswald H. Polymerized hemoglobin restores cardiovascular and kidney function in endotoxin-induced shock in the rat. The Journal of Clinical Investigation. 99: 47-54. PMID 9011575 DOI: 10.1172/JCI119132  1
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